152 results about "Cervix" patented technology

The utility model relates to a cervical conization knife, and belongs to the field of gynecological operation instruments. Comprising a knife handle and a detachable blade. And the front end 2 of the knife handle tilts and forms an angle with the longitudinal axis of the handheld end 1 of the knife handle. According to different angles between the longitudinal axis of the front end 2 of the scalpel handle and the longitudinal axis of the handheld end 1 of the scalpel handle, the scalpel is divided into three models of A, B and C which are respectively at angles of 27 degrees, 31 degrees and 37 degrees. The cross section of the blade body is arc-shaped, the radian is consistent with that of the cervix uteri, the arc length is 1 / 8 of the circumference of the cervix uteri, namely 1cm, the two sides of the blade are both blade faces 3, the front ends of the blade faces 3 converge to enable the blade tip 4 to be an arc-shaped triangle, the rear end 5 of the blade is a parallel blunt face, and the longitudinal axis of the blade is provided with scales 6. Compared with a traditional cold knife, the novel cervical cold knife can be applied to gynecology cervical cold knife conization, surgical operation is facilitated, a cut cone can be regular, cervical injury is reduced, and the shape and the function of the cervix are reserved to the maximum extent.

The utility model provides an adjustable cold knife for cervical conization, which belongs to the field of medical instruments and comprises a handle, an adjusting component for adjusting the depth of the knife is slidably mounted in the handle, and an excision component for cervical conization is hinged to the top of the adjusting component. When the control sliding block is pushed slightly, the cutter bar can stably slide along the limiting groove and extend out of the handle, the limiting groove provides stable guidance for sliding of the control sliding block, it is ensured that the control sliding block always keeps linear movement, and then the cutter bar moves accurately without errors; therefore, it is guaranteed that the cutting depth is accurate, the whole operation process is simple, convenient and rapid, the adjusting precision is extremely high, and adjustment can be conducted according to different operation requirements.

The invention provides equipment, a method and a system for evaluating prognosis of cervical cancer, squamous carcinoma and adenocarcinoma and application of the equipment, the method and the system, and belongs to the technical field of medical evaluation. Two biomarkers, namely adenylate kinase 4 and cavernous malformation 2 protein, for evaluating prognosis of cervical squamous cell carcinoma and adenocarcinoma are obtained through multivariate statistical analysis, difference screening, COX regression analysis and other biosignal analysis methods. Based on the biomarker, evaluation equipment, a computer execution method, a computer system and the like for evaluating the prognosis of cervical squamous cell carcinoma and adenocarcinoma are constructed, and the evaluation equipment, the computer execution method, the computer system and the like are used for accurately judging the prognosis condition of a cervical cancer patient.

The invention provides a uterine cavity balloon supporting device and a preparation method, which are used for solving the problem that in the prior art, when a supporting head is used, cervical injury is easily caused. The catheter comprises a first catheter body, a second catheter body and a supporting head made of flexible materials. The supporting head is made of the flexible material, when the expansion medium is conveyed into the supporting head through the conveying channel formed between the inner side wall of the second catheter and the inner side wall of the first catheter, the supporting head can deform and expand to be in the uterine cavity shape, the supporting head can support the uterine cavity, and intrauterine adhesion is prevented. After use, the supporting head can be attached to the first catheter by drawing out the expansion medium in the supporting head, so that the supporting head can be taken out of the human body conveniently. Therefore, the situation that the uterine cavity is scalded due to the fact that liquid with different temperatures is input, and the supporting head is still in an expanded state after use, so that when the supporting head is taken out, the supporting head clamps the cervix uteri, the supporting head is inconvenient to take out and the cervix uteri is injured is avoided.

The invention discloses a cervix uteri and vagina exfoliated cell sampling device for self-sampling HPV (human papillomavirus) detection, which comprises a handle, one end of the handle is fixedly connected with a spherical head body, a sampling brush head is fixedly arranged on the outer side of one end of the spherical head body of the handle, and sampling brushes are uniformly arranged on the surface of the spherical head body. The outer side of the handle is sleeved with a slidable telescopic sleeve shell, and when sampling operation needs to be carried out, the telescopic sleeve shell can slide away from one side of the sampling brush head and one side of the sampling brush brush by sliding the telescopic sleeve shell, so that the sampling brush head and the sampling brush brush are exposed to be used for collecting cervical and vagina exfoliated cells; in a non-sampling state, the sampling brush head and the sampling brush can be sleeved with the telescopic sleeve shell, so that a protection effect is achieved; compared with a traditional sampling brush or cotton swab, the contact area between the sampling brush or cotton swab and the cervix uteri and the vagina wall is greatly increased, the area where pathological cells possibly exist can be covered more comprehensively, the risk of missing sampling is reduced, and the accuracy of a detection result is improved.

The invention relates to the technical field of biological detection, and discloses a reagent composition and a kit for detecting cervical cancer and precancerous lesions of cervical cancer and application of the reagent composition and the kit. The reagent composition provided by the invention is used for detecting the methylation degree of a specific marker gene, and the detection sensitivity and specificity of cervical cancer and high-grade cervical cancer precancerous lesions are at a relatively high level. When the reagent composition is used for screening cervical cancer and precancerous lesions of HPV positive people, compared with conventional cytological detection, the colposcope referral rate is greatly reduced, meanwhile, the detection times for definite diagnosis of high-grade cervical lesions or cervical cancer are reduced, and the waste of medical resources and the examination burden of patients are reduced.

An inflatable speculum device for more comfortably and conveniently expanding the vaginal cavity to facilitate visualization of the cervix includes a tube having an interior space. The tube is made of a resiliently deformable material wherein the tube is configured to inflate. A hose is couplable to the tube and is in environmental communication with the interior space of the tube. A pump is fluidly coupled to the hose wherein activation of the pump moves air into the interior space of the tube through the hose thereby inflating the tube. The tube fits within a body cavity of a user whereby the tube is configured to dilate the body cavity when the tube inflates.

The invention relates to the technical field of medical information, in particular to a placenta position detection system and method based on MRI, and the method comprises the steps: obtaining target MRI image data, carrying out the image segmentation of the target MRI image data, and extracting the three-dimensional models of a placenta, a uterus and a cervix; based on the three-dimensional model, identifying the position relationship between the placenta and the cervix uteri, judging the type of the placenta, and evaluating the placenta implantation risk to generate risk early warning information; and displaying a three-dimensional visual model of the placenta and the uterus, and marking a high-risk area on the three-dimensional visual model based on the risk early warning information. The placenta position detection efficiency, precision and automation are improved, full-process automatic detection can be achieved, and personal errors are reduced.

There is provided a computer system and a computer-implemented method for prediction of parameters indicative of the risk of spontaneous preterm birth (sPTB) for a subject under assessment, the method being executed by at least one hardware processor and comprising the steps of: providing one or more ultrasound images comprising medical image data representative of the anatomical structure and appearance of at least a part of a cervix of the subject; providing a plurality of segmentations of the medical image data each representative of one or more features of the anatomical structure and appearance of the at least a part of the cervix of the subject; and utilizing i) the medical image data, ii) spatial information associated with the medical image data and iii) one or more of the segmentations in a classifier model to determine a prediction metric indicative of the likelihood of sPTB for the subject.

This invention provides a transcervical access system for moving fluids transcervically. [Solution] The transcervical access system 100 is effective in transferring a wide range of fluids into the uterine cavity, including the delivery of a hydrogel precursor, saline solution, and imaging fluid. The transcervical access system 100 is also effective in removing fluids, such as residual bodily fluids, residual fluids from procedures, or tissue from the uterine cavity. The transcervical access system 100 includes a flow limiter, such as an outflow limiter 106 and / or a cervical plug. A method of using the transcervical access system 100 involves using the transcervical access system 100 to transcervically access the uterine cavity and to install the hydrogel. The transcervical access system 100 and related methods are useful in preventing adhesions after intrauterine procedures by providing a biodegradable hydrogel within the uterine cavity, including the cervix.

The utility model discloses a kind of hysteroscope liquid leakage prevention structures, including center cylinder base, the both ends of center cylinder base are fixedly connected with end fixed ring, the outer end array of two sides the end fixed ring is fixedly connected with multiple elastic supporting pieces, and the outer end of multiple elastic supporting pieces of same side is equipped with silica gel outer cover, two sides The outer side of elastic supporting piece is fixedly connected with operating slip ring and insertion stop seat respectively, and the outer end of two sides silica gel outer cover is fixedly connected with the outer edge of corresponding side operating slip ring and insertion stop seat.In insertion, small in diameter, it is convenient to set, and will not cause damage to cervix, can effectively solve the problem of clinical surgeon encountered in hysteroscopy surgery in uterine cavity liquid leakage, reduce operation time and surgical complications, improve operation efficiency and safety.

1. The name of the design product: disposable uterine cavity imaging catheter. 2. The use of the design product: through the cervix into the uterine cavity, for the diagnosis and auxiliary operation of uterine cavity diseases. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view 1.

The present application relates to in situ model modeling method, especially for a kind of non-invasive cervical cancer in situ model modeling method of mouse, including selecting several 8 weeks old BALB / c-nude mouse, all mice are divided into non-invasive group and operation group, the age, weight of two groups of mice are compared, and there is no statistically significant difference;Non-invasive group is widened with the cotton stick of diameter 3mm and wipes dry vagina, the tumor block with luciferase fluorescence is immersed in modified hydrogel, after heating and making modified hydrogel solidification, the tissue glue mixed with hard gypsum in modified hydrogel is dropped on the surface of modified hydrogel and quickly inserted into vagina, when there is obstruction, stop deepening, pause 30s and wait for tissue glue to be completely dry, when tumor block is fixed in cervix, it is modeling completion;Operation group first opens abdominal cavity, and tumor tissue of same size is sutured on cervix.This kind of non-invasive cervical cancer in situ model modeling method of mouse, using non-invasive method to replace operation method to establish non-invasive cervical cancer in situ model, can reduce the pain of mouse, reduce experimental difficulty.

The invention relates to the technical field of medical instruments, in particular to a cervicitis treatment drug delivery device which comprises a cabinet. A dosing mechanism for dosing is mounted on the inner side wall of the cabinet body, a cleaning mechanism for cleaning the dosing mechanism is mounted on the inner bottom wall of the cabinet body, and a dispensing mechanism for dispensing is mounted on the inner top wall of the cabinet body; in the using process of the device, the drug administration barrel is inserted into the vagina of a patient, then the micro motor is started to drive the sector plate to rotate, and drugs are discharged through the drug administration hole, so that the drugs are directly scattered to the cervix uteri, drug waste caused by the fact that the drugs are scattered into the vagina in the drug administration process is avoided, the drugs are effectively applied to the patient, treatment of the patient is facilitated, and time and labor are saved; and the labor intensity of medical staff is reduced.

The invention relates to the technical field of ultrasonic image analysis, and discloses an image detection method and system for prolonging the second birth process of double-fetal vaginal delivery and SPPH risk based on ultrasonic Speckle-tracing, and the method comprises the steps: obtaining an ultrasonic two-dimensional gray-scale image sequence; marking a conjoint analysis area between the cervical wall and the front and rear walls of the vagina; constructing a joint area displacement field; constructing a joint region strain trajectory; extracting parturition process characteristic indexes; and executing risk assessment through a fuzzy rule. The technical problem that in the prior art, risk judgment depends on clinical experience, and especially under the condition that continuous stretching occurs on the cervix uteri and vagina combined wall in the second birth process of double-fetal vaginal delivery, early recognition of the evolution process of the tissue from reversible stretching to irreversible instability is difficult to achieve is solved. Due to the fact that joint area displacement field modeling and logarithmic nonlinear strain analysis are introduced, quantitative characterization and continuous risk description of the mechanical behavior of the tissue in the labor process are achieved.

The invention patent is titled "Dragon and Cypress Gel," belonging to the pharmaceutical category. The main components of Dragon and Cypress Gel are: Phellodendron bark, earthworm, dragon's blood, Oldenlandia diffusa, Sophora flavescens, and Bletilla striata. In recent years, research on cervicitis and cervical lesions has shown good results using external treatments of traditional Chinese medicine. Vaginal cervical medications are characterized by high local drug concentration, low dosage, and safety and effectiveness, receiving high clinical evaluation. The vagina and cervix have abundant capillaries and lymphatic vessels, and lack clearly defined nerve endings, resulting in minimal pain stimulation for patients during administration. This makes it an effective drug release site for specific diseases such as cervicitis and vaginitis. Traditional Chinese medicine gels are a novel type of external preparation of traditional Chinese medicine. They are made by dissolving or uniformly dispersing traditional Chinese medicine in a gel. These gels adhere tightly to the treatment site for a relatively long time, exhibiting good bioadhesion, and are simple to prepare. It is suitable for use on skin, mucous membranes and cavities. It not only avoids the first-pass effect of enzymes and acids in the gastrointestinal tract that exists in oral administration, but also reduces the adverse reactions of drugs. It has the characteristics of good spreadability, non-greasy feeling, easy to wash off, good transdermal absorption, and comfortable use.

Embodiments of the present application provide a method for determining a region of interest in an ultrasound image and an ultrasound imaging device. The method comprises: acquiring a uterine ultrasound image and displaying the uterine ultrasound image via a display interface; determining first feature points of the endometrium in the uterine ultrasound image, the first feature points comprising a feature point located at the cervix and a feature point located at the fundus; automatically connecting the first feature points comprising the feature points of the cervix and the fundus according to the direction of the endometrium to form an endometrial boundary line of the endometrium; and determining the region in the uterine ultrasound image between at least the endometrial boundary lines as the region of interest. This application can improve the accuracy and efficiency of determining a region of interest that aligns with the endometrial / junctional zone morphology.

The present invention describes a method of treating a high level of squamous intraepithelial lesion (HSIL) associated with human papilloma virus (HPV) type 16 or HPV type 18 of the cervix. The described methods include assessing the presence or absence of miRNA and isomiRs thereof in one or more biological samples.

The present application relates to the medical instrument related technical field, especially the sterile latex vaginal flusher, including holding shell group, water storage tank, multi-section pipe group, linkage assembly, three-leaf plate, locking assembly, the present application is through the step-by-step movement of multi-section pipe group and human structure self-adaptive design, solve the existing rigid flusher fragile mucosa friction causes the problem of pain.In the insertion and flushing process can conform to the physiological structure of vagina, reduce the mechanical friction and stimulation to hyperemic mucosa, effectively reduce the pain of patients, at the same time, through the cooperation of three-leaf plate and locking assembly, the insertion depth is accurately limited, prevent the pipe head from hitting the cervix and causing severe pain, so that the treatment effect is guaranteed, the physiological pain and psychological burden of patients are reduced to the greatest extent.

Antibody drug conjugate (ADC) comprising a drug moiety conjugated to antibody or antigen binding fragments thereof that bind to TROP2 disclosed herein, as well as methods of use thereof. Methods of use include, without limitation, cancer therapies and diagnostics. The ADC of the disclosure can bind to certain cancer cell surfaces. Exemplary targets of the ADC disclosed herein can include carcinomas, such as lung cancer, breast cancer, head-and-neck cancer, esophagus cancer, stomach cancer, bladder cancer, pancreatic cancer, colorectal cancer, cervix cancer, endometrial cancer, ovarian cancer, laryngeal cancer, prostate cancer, thyroid cancer and oral cancer.

A menstrual insert includes a flexible, ultra-absorbent pad that conforms to the vaginal anatomy, including the cervix. The insert is designed to be leak-resistant, body-adaptive, and undetectable during wear. A retrieval loop or string allows for safe removal. The insert may be infused with medicinal agents for pH balance or anti-inflammatory relief. It can be inserted manually or using an applicator with a plunger mechanism. The applicator facilitates precise placement and easy removal, ensuring maximum comfort and effectiveness.

The invention relates to the technical field of gynecological sampling, and discloses a gynecological secretion sampling swab and detection device.The gynecological secretion sampling swab comprises a handheld rod, a brush head and a flocking head, the brush head is arranged at one end of the handheld rod and used for collecting secretion at the cervix uteri of a patient, and the flocking head is arranged on the outer surface of the handheld rod and arranged in an arc shape; the sampling end of the flocking head is close to the brush head so as to be used for collecting secretions at the uterus and the fornix of a patient; by arranging a double-sampling structure with the brush head and the arc-shaped flocking head, secretion collection of the cervix uteri and the fornix uteri can be completed at the same time in single operation, and the device has the advantages that secretion samples of the cervix uteri and the fornix uteri can be obtained at the same time through single sampling, and the sampling efficiency is improved.

The application discloses a gel preparation preparation method for improving cervical HPV infection and establishing a preventive barrier, relates to the technical field of gel preparation, and aims to solve the technical problems that the existing treatment methods are mostly focused on treating infected patients, and there are obvious deficiencies in the prevention of HPV infection, especially in establishing an effective preventive barrier in uninfected people, including: a crushing mechanism, which is mainly used for crushing raw materials, the crushing mechanism comprises a cabinet body, a cabinet door is arranged on one side of the cabinet body, a crushing barrel is arranged in the cabinet door, and a rotating motor matched with the crushing barrel is arranged on the cabinet door; a reverse osmosis mechanism, which is mainly used for controlling the osmotic pressure of the gel. The application has the advantages of activating local immune cells of the cervix, promoting cytokine secretion, enhancing the immune clearance ability of the body to HPV virus, providing long-acting preventive protection for the cervix, and reducing the risk of HPV infection.

1. The name of the product of this design: Vaginal speculum (multi-leaf synchronous expansion and contraction type). 2. Application of this product design: For examination of the interior of the vagina, cervix and related parts. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The utility model relates to the technical field of vaginal dilators, in particular to a vaginal dilator with a medicine applying function, which is characterized in that a supporting mechanism extends into the vagina of a patient, the supporting mechanism opens the vagina of the patient, medicine is discharged into a medicine applying mechanism through a conveying mechanism, and then the medicine is sprayed into the vagina of the patient through the medicine applying mechanism. Medicine is applied to the vagina and the cervix uteri of a patient, so that the practicability of equipment is improved; comprising a supporting mechanism; the device further comprises a medicine feeding mechanism and a conveying mechanism, the medicine feeding mechanism is installed on the supporting mechanism, and the conveying mechanism is installed on the medicine feeding mechanism. The supporting mechanism supports the vagina of a patient, the conveying mechanism conveys medicine, and the medicine applying mechanism applies medicine to the vagina and the cervix uteri of the patient.

The utility model discloses a cervix uteri sampling device. The cervix uteri sampling device comprises an operating rod, a first sampling structure and a second sampling structure, the operating rod is provided with a first end and a second end which are opposite in the first direction, the first sampling structure comprises a first base body and a plurality of first brushes, the first base body is inserted into the first end in an interference mode in the first direction, the first brushes are arranged in the direction surrounding the first direction, and the first brushes are arranged on the peripheral side of the first base body. The second sampling structure comprises two second base bodies which are oppositely arranged in the second direction and a plurality of second brushes, the two second base bodies are connected, the two second base bodies are integrally arranged on the periphery of the first end in a sliding and sleeving mode, and the second brushes are arranged on the sides, away from the second end, of the second base bodies; according to the cervix uteri sampling device, sampling personnel can sample the cervix uteri inside the cervix uteri and the cervix uteri fornix at the same time, the sampling operation difficulty is small, and the sampling position accuracy is high.

Systems, devices, and methods are provided that control, support, and / or elongate a cervix to treat pregnancy complications and / or delay an onset of labor so that a gestational period for a fetus may be extended, thereby preventing preterm labor and delivery of the fetus. The systems and devices may be made by assembling a molded component configured to have a main body with a groove therein and a flange. During manufacturing, the flange may be inserted into the groove and bonded therein to form a cervical cuff balloon and a positioning balloon may be attached to an external surface of the main body. The molded component may further include an inflation media conduit in communication with the cervical cuff balloon.

The invention provides a leakproof hysteroscope, and relates to the field of medical instruments, the leakproof hysteroscope comprises a main pipe, one end of the main pipe is fixedly connected with an extension pipe, the surface of the extension pipe is sleeved with an air bag part, the top of the outer arc surface of one end of the air bag part is provided with a liquid inlet pipe, the middle of the main pipe is movably clamped with a support, and one end of the liquid inlet pipe is movably clamped on the support; connecting pieces are fixedly connected to the bottoms of the outer surfaces of the main pipes. Through the arrangement of the support, the air bag part, the liquid inlet pipe, the water stop ball, the connecting rod, the temporary storage part and the flowing groove, liquid injection operation on the device is achieved, the air bag part is effectively expanded, the inner wall of the cervix uteri is gradually extruded and attached, then the gap between the cervix uteri and the device is reduced, medium leakage is effectively avoided, and the problem that in the prior art, in the using process, medium leakage is caused is solved. Cervical relaxation of a patient is very easy to occur due to fetus, normal delivery, uterine curettage or multiple induced abortion times, frequent perineal examination, delivery injury and the like, and the problem of medium leakage is very easy to occur due to the fact that the number of the cervical relaxation is combined with cervical hypertrophy.

The invention provides a HPV mRNA lipid nanoparticle vaccine, comprising an open reading frame encoding a fusion protein of E2, E6 and E7 antigens of a high-risk HPV antigen. The invention also provides a method for treating and preventing HPV infection related diseases such as cervical cancer, cervical precancerous lesions, high-grade intraepithelial lesions of the cervix, high-grade squamous intraepithelial lesions (HSIL) or cervical intraepithelial neoplasia (CIN).

An imaging device may during a pelvic examination, illuminate a tissue with a blue light, the tissue including at least one of a cervix uteri or vaginal wall. The blue light has a wavelength of between 390 nm and 480 nm and is selected to induce fluorescence in at least one biomarker in cells of the tissue, resulting in fluoresced tissue. An imaging device may capture an image of the tissue including the fluoresced tissue. An imaging device may identify, in the image, an indication of cancer based on the fluoresced tissue.