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1665 results about "Lesion" patented technology

A lesion is any damage or abnormal change in the tissue of an organism, usually caused by disease or trauma. Lesion is derived from the Latin laesio "injury". Lesions may occur in plants as well as animals.

Agricultural pest early warning method and system based on big data

The invention provides an agricultural pest early warning method and system based on big data, and the method comprises the steps: firstly obtaining a crop leaf image set of a target farmland region from farmland image big data, and carrying out the leaf region segmentation of the crop leaf image set, so as to distinguish a healthy region from a potential lesion region; performing disease feature extraction on the potential lesion area image to generate a key disease feature set, performing abnormal state detection on the key disease feature set by using a pre-trained disease and pest recognition model, determining a disease and pest type and predicting a diffusion trend of the disease and pest type; and finally, based on the disease and insect pest type identification and the diffusion trend prediction data, generating a disease and insect pest early warning instruction containing geographic positioning information, and sending the instruction to a farmland management system to trigger prevention and control response operation, thereby realizing accurate monitoring and early warning of crop diseases and insect pests.
Owner:CHENGDU PAIWO ZHITONG TECH CO LTD

Coronary angiography image blood vessel segmentation system based on multi-scale feature fusion

The invention discloses a coronary angiography image blood vessel segmentation system based on multi-scale feature fusion. According to the invention, through the innovative design of the adaptive morphological sensing module, the system can dynamically analyze the anatomical structure characteristics of the blood vessel: the differentiable morphological operation layer converts the corrosion expansion operation into a learnable feature extraction process, so that the network can autonomously identify the gradient change and boundary trend of the blood vessel wall; the dynamic nuclear adaptation mechanism adjusts the scale and direction of morphological operation in real time according to the local blood vessel diameter and curvature characteristics, interference of surrounding tissues in a main blood vessel area can be inhibited, and continuous expression can be enhanced for capillary branches. Through deep fusion of dissection driving and data driving, the topological structure integrity of a segmentation result at a blood vessel bifurcation point and a narrow lesion area is remarkably improved, and the common problems of blood vessel fracture and misconnection in a traditional method are effectively avoided.
Owner:SOUTHWEAT UNIV OF SCI & TECH

Ultrasonic image diagnosis system and method

The invention relates to the technical field of sound wave measurement, in particular to an ultrasonic image diagnosis system and method.According to the ultrasonic image diagnosis system and method, matching between reflection characteristics and tissue characteristics is made to have the self-adaptive learning ability through a deep neural network, the targeted recognition effect is improved in the aspect of signal classification, and based on the judgment result of the reflection characteristics, the diagnosis accuracy is improved. When boundary partitioning is carried out on a tissue area, the edge structure is judged by using the combination of three parameters of gray range, gradient direction and texture continuity, contour fuzziness caused by single index judgment is avoided, and the boundary partitioning accuracy is improved by extracting a gray distribution center, an amplitude change track and an edge area continuous change sequence. And the region positioning result is input into a support vector machine, accurate recognition of lesion properties is realized according to boundary classification comparison of morphological structure quantitative features and historical benign and malignant feature data, secondary verification of the structural form is performed after the image is formed, and the diagnosis integrity and the judgment confidence are effectively improved.
Owner:THE FIRST AFFILIATED HOSPITAL OF FUJIAN MEDICAL UNIV

Bone joint lesion area automatic labeling method and system based on image processing

The invention discloses a bone joint lesion area automatic labeling method and system based on image processing, and belongs to the field of bone joint lesion area labeling. According to the invention, a bone joint reflection signal is obtained by combining the polarization-state-adjustable laser light source with polarization-sensitive optical coherence tomography, and a three-dimensional birefringence distribution diagram is generated through matrix analysis. And after non-local mean filtering is carried out on the distribution map, a lesion edge contour is extracted based on a dynamic gradient amplitude, and a binary mask is generated. Mask pixels are converted into network nodes containing space coordinates, gradient directions and birefringence, and a topological network is constructed based on the Euclidean distance of adjacent pixels. The weight is calculated through the node intersection density and the birefringence, and a graph attention network is utilized to aggregate multi-layer features to extract lesion topological features. The features are mapped to a three-dimensional space to construct a lesion probability distribution field, an interactive labeling result is generated through contour surface extraction and transparency mixed rendering, and the accuracy of labeling the complex lesion area of the bone joint can be improved.
Owner:LIAONING MEDICAL LETTER TECH CO LTD

Colorectal lesion multi-modal classification method based on pathological attention and multi-instance learning

A colorectal lesion multi-modal classification method based on pathological attention and multi-instance learning constructs an efficient automatic diagnosis model by fusing visual features and a textual prototype defined by pathology experts. The method comprises the following steps: collecting histopathological image data, segmenting the histopathological image data into standardized image blocks, and extracting visual features by using a pre-training feature extraction network after color standardization and noise processing; a multi-instance learning framework and a pathological attention mechanism are combined, feature space distribution of a text prototype is adjusted in a self-adaptive mode through a dynamic prototype optimization module, and optimization targets of visual clustering and cross-modal semantic alignment are balanced by adopting a gradient perception double-loss dynamic weighting strategy; and after the model is trained in stages, the generalization performance is verified in an external data set. According to the method, the classification precision is remarkably improved, the method can adapt to dyeing difference and tissue heterogeneity without pixel-level labeling, the accuracy rate in cross-center verification is superior to that of an existing reference model, and the efficiency of pathological diagnosis is greatly improved.
Owner:TSINGHUA SHENZHEN INTERNATIONAL GRADUATE SCHOOL

Electronic clinical medical assessment method and system for ophthalmology diagnosis and treatment scheme

The invention provides an electronic clinical medical assessment method and system for an ophthalmology diagnosis and treatment scheme, and relates to the technical field of medical information, and the method comprises the steps: 1, carrying out the multi-scale edge detection calculation of an input ophthalmology image-text mixed medical record image, and obtaining a medical record image; the method comprises the following steps: extracting a boundary contour of a text labeling area and a hand-drawn lesion schematic diagram through adaptive threshold segmentation and morphological closed operation, and establishing a coordinate mapping table containing text block circumscribed rectangular coordinates, geometric positions of key anatomical mark points of the schematic diagram and symbol spacing characteristics; 2, constructing a two-channel attention gating network based on the coordinate mapping table, fusing the semantic features of the text region and the morphological features of the schematic diagram through a dynamic weight distribution strategy, and generating a multi-modal fusion feature matrix with a spatial alignment relationship; according to the method, through multi-modal feature fusion, triangular verification region confidence regulation and control and three-dimensional topology modeling, analysis and structured output of ophthalmology image-text medical records are realized, and the spatial alignment of diagnosis and treatment information is improved.
Owner:PEOPLES HOSPITAL OF INNER MONGOLIA AUTONOMOUS REGION

Real-time recognition and positioning method and system for breast duct inner wall lesion based on optical fiber imaging

The invention provides a real-time breast duct inner wall lesion recognition and positioning method and system based on optical fiber imaging, and relates to the technical field of medical image processing, and the method comprises the steps: obtaining a breast duct inner wall image sequence, extracting a displacement vector field, decomposing the displacement vector field into a dominant frequency and residual components, analyzing the dominant frequency phase to obtain a tissue motion period, an abnormal displacement area is screened from the residual error to establish a tissue anomaly map, an area descriptor is constructed through local wavelet coefficient analysis, a lesion core area is determined through density clustering, and finally the range and the expansion direction of a lesion area are determined through a multi-scale radial basis function and isoline analysis. According to the invention, real-time accurate identification and positioning of the lesion of the inner wall of the breast duct can be realized.
Owner:BEIJING ZHONGYAN HAIKANG TECH CO LTD

Image segmentation labeling method and system based on machine learning

The invention provides an image segmentation labeling method and system based on machine learning, and relates to the technical field of computer vision, and the method comprises the steps: dynamically selecting three detection points in a key region of a segmentation boundary based on the boundary form of an initial segmentation result, and constructing a dynamic triangular mesh unit; calculating a geometric characteristic value according to the vertex coordinates of the dynamic triangular mesh unit, wherein the geometric characteristic value comprises a proportional relation between the area and the side length of the triangular mesh unit; comparing the geometric characteristic value with a preset threshold range, and if the geometric characteristic value exceeds the threshold range, generating a boundary coordinate correction parameter; and adjusting boundary coordinates of the lung region segmentation result according to the correction parameter, and generating a corrected lung region segmentation result. Through end-to-end operation from image acquisition to lesion marking, the workload of doctors is reduced, and based on the segmentation result, the lesion marking unit can accurately position the lesion position.
Owner:SHANGHAI XIAOLING NETWORK TECH CO LTD

Oral tooth lesion AI auxiliary diagnosis system

The invention discloses an oral tooth lesion AI auxiliary diagnosis system, which belongs to the field of artificial intelligence and comprises an image acquisition module, a three-dimensional modeling module, a lesion marking module, a dual-channel feature extraction module, a cross-modal diagnosis reasoning module, a lesion evolution trend prediction module and a dynamic risk level generation module. The image acquisition module utilizes multi-frequency structured light and a polarization camera to cooperatively acquire oral images; the three-dimensional modeling module is used for reconstructing an upper and lower jaw three-dimensional structure based on edge constraint splicing point clouds and registering images to form double-view fusion data; the lesion labeling module fuses expert labeling and weak supervision pseudo labels to generate joint labels; the dual-channel module extracts skeleton and texture features; the reasoning module realizes cross-modal semantic coupling through an image-text co-occurrence graph; the evolution prediction module models a lesion change path based on the time reversal causal network; and the risk module outputs a five-level risk and re-injects the embedded vector to strengthen prediction. The beneficial effects are that diagnosis intelligence and clinical decision support level are obviously improved.
Owner:BEIJING FUAN NETWORK TECHNOLOGY CO LTD

Picture generation method based on multi-scale features

The invention relates to the technical field of picture generation, in particular to a picture generation method based on multi-scale features. The method comprises the following steps: firstly, collecting medical images, patient data and lesion stage information under different equipment and acquisition parameters, after screening preprocessing, constructing and training a multi-scale VQ-VAE model, introducing an attention mechanism, and adopting adaptive codebook updating and multi-codebook fusion quantification; then, a hierarchical autoregression model based on a Transform decoder is constructed and trained, and lesion stage information is fused into the hierarchical autoregression model; and finally, inputting specific lesion stage information, generating a multi-scale discrete index sequence through a hierarchical autoregression model, converting the multi-scale discrete index sequence into a codeword vector through a multi-scale VQ-VAE model, and finally generating a simulated medical image. According to the scheme, the multi-scale VQ-VAE model is utilized to encode the input image into the multi-scale discrete feature representation, and meanwhile, the autoregression model is applied to the discrete hidden space of the VQ-VAE, so that the distribution of the discrete representation sequence can be effectively modeled, and the medical image with higher quality and more realistic sense can be generated.
Owner:DATA TRANSMISSION GRP

Assessment method of diabetic foot based on wound image recognition

The invention discloses a diabetic foot assessment method based on wound image recognition. The method comprises the following steps: processing a foot infrared thermal imaging image to generate a temperature anomaly graph; fusing the foot wound image and the temperature anomaly graph to generate a fused image; constructing a foot blood flow analysis model, extracting a blood flow influence factor, and correcting the fused image through the blood flow influence factor; and constructing a joint assessment model, taking the corrected fusion image and historical data of the diabetic foot patient as input of the joint assessment model, predicting a risk assessment level of the diabetic foot, and outputting a disease assessment result of the diabetic foot patient according to the risk assessment level. According to the method, multi-modal medical image fusion analysis is realized, the accuracy of wound area positioning and pathological state expression is improved, the accuracy of lesion area recognition is improved, the illness worsening risk can be predicted in advance, clinical decision can be assisted, the risk of serious complications such as amputation of a patient is reduced, and the prognosis and life quality of the patient are improved.
Owner:FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA

Multi-modal large language model for generating hepatocellular carcinoma key pathological diagnosis report

The invention provides a multi-modal large language model for generating a hepatocellular carcinoma key pathological diagnosis report, a framework main body is a visual coding module, and a multi-modal feature alignment module, a multi-head low-rank attention mechanism, an enhanced medical MoE mechanism and a structured output decoding layer are also introduced. The visual coding module is constructed on the basis of a Swin Transform architecture, visual pre-training is completed on hepatocellular carcinoma MRI data, and after a task specific classification head is stripped, a trunk feature extraction network is reserved to serve as an image modal representation encoder. The multi-modal feature alignment module guides the model to learn a cross-modal semantic mapping relation between a hepatocellular carcinoma MRI image and a key pathological diagnosis report language, image modal input is a visual feature sequence, and text modal output is a structured description text; and the structured output decoding layer generates six types of liver cancer focus attributes. According to the method, the pre-operative multi-parameter and multi-stage enhanced MRI image is utilized, and the open-source large model is finely adjusted to generate a matched liver cancer postoperative pathology report.
Owner:MENGCHAO HEPATOBILIARY HOSPITAL OF FUJIAN MEDICAL UNIV

Multi-modal fusion anorectal data visualization analysis method and system

The invention relates to the technical field of data visualization, in particular to a multi-modal fusion anorectal data visualization analysis method and system, and the method comprises the following steps: synchronously collecting an anorectal image and a pressure signal, aligning a timestamp, carrying out the preprocessing, outputting a standardized image and a coded physiological signal, and extracting edge and texture features. After LSTM coding, splicing with image features, and fusing into a joint feature map; generating a multi-scale heat map by the feature pyramid network, and coarsely positioning a lesion; after boundary optimization, U-Net recovers details, and a pixel-level lesion probability graph is output; superposing the Jet color gradation to the original image in a semitransparent manner, and marking a pressure abnormal time period; and performing weighted scoring to generate a fourth-level clinical suggestion. According to the anorectal disease diagnosis method, through multi-modal space-time alignment, multi-scale feature fusion, boundary optimization and a quantitative scoring system, the problems of data splitting, insufficient precision and low efficiency of a traditional method are solved, a high-precision and high-robustness intelligent diagnosis tool is provided for anorectal diseases, and the scientificity and efficiency of clinical decision making are remarkably improved.
Owner:南通市中医院(南通市中医研究所)

Method for intelligently describing liver space-occupying lesion ultrasonic image content by using LLM

The invention relates to the technical field of medical image processing, and discloses a method for intelligently describing liver space-occupying lesion ultrasonic image content by using LLM. A liver ultrasonic image sequence, a patient historical medical record text and a blood biochemical index vector are obtained through a multi-modal data acquisition module, and features are extracted through a cross-modal contrast learning network to generate embedded vectors and align the embedded vectors. And inputting the aligned image embedding vector into a dynamic context sensing decoder, and generating a description text semantic mark sequence by using a layered multi-head attention mechanism. The confidence coefficient is evaluated through an uncertainty calibration module, and the text is optimized through a post-processing reordering mechanism when the confidence coefficient is lower than a threshold value. A real-time interaction optimization mechanism is further arranged, and the model is updated according to feedback of doctors. According to the method, multi-modal data are fused, description accuracy and reliability are improved, text quality is optimized, clinical requirements are met, and liver disease diagnosis is assisted.
Owner:THE FIRST AFFILIATED HOSPITAL OF WENZHOU MEDICAL UNIV

Cervical LSIL progress risk prediction method and system based on multi-modal time sequence fusion

The invention discloses a cervical LSIL progress risk prediction method and system based on multi-modal time sequence fusion, and the method comprises the steps: collecting multi-modal data, and carrying out the standardization processing; extracting dynamic change characteristics in continuous annual TCT liquid-based pictures through a convolutional neural network, and positioning a high-risk cell region; carrying out interval sensing position coding on HPV detection records, constructing an inter-modal causal attention mechanism, and establishing a time sequence causal relationship between HPV infection events and cell abnormal evolution; a discrete time competition risk model is adopted, the progression, regression and maintenance probabilities of different time periods in the future after primary diagnosis are synchronously output, a time-varying covariable LSTM is introduced, and the weight of patient features changing along with time is dynamically updated; and generating a cell evolution thermodynamic diagram, marking a high-risk area space-time evolution path, outputting a time influence curve, and marking a key risk accumulation time window. According to the invention, accurate quantitative evaluation of the cervical low-level lesion progress risk is realized.
Owner:NANJING DRUM TOWER HOSPITAL

Retinochoroidal disease course structure change monitoring system based on artificial intelligence

The invention relates to the technical field of medical image processing and artificial intelligence, and discloses an artificial intelligence-based retinochoroid disease course structure change monitoring system, which comprises an image acquisition unit, a feature extraction unit, a lesion segmentation unit and the like. The image acquisition unit acquires retina optical coherence tomography sequence image data and fundus color image data; the feature extraction unit extracts a retina choroidal structure feature tensor through a three-dimensional convolutional neural network; the lesion segmentation unit outputs a lesion area probability distribution diagram by using a U-Net segmentation network; the time sequence alignment unit is used for registering the multi-time-point images to generate a displacement change matrix; the dynamic analysis unit extracts related indexes; an abnormal scoring unit constructs a disease course progress score; the decision grading unit outputs disease course stage classification labels; the multi-modal fusion unit fuses the multi-modal features; the report generation unit generates a structured disease course monitoring report. And favorable support is provided for diagnosis and treatment of ophthalmic diseases and illness state tracking.
Owner:TIANJIN EYE HOSPITAL

Embedded electroencephalogram signal acquisition device and system

The invention relates to the field of biomedical engineering, and discloses an embedded electroencephalogram signal collecting device and system.The device comprises a power management module, a plurality of electrode assemblies, a control module and a storage and communication module; through a control module designed by a system on chip SoC and a multi-electrode assembly in contact with intracranial nerves, the embedded electroencephalogram signal acquisition device which is in multi-level cooperation, supports user-defined sampling parameters and self-adaptive strategies and meets individual requirements of different focus monitoring scenes is constructed. High-precision distributed acquisition and self-adaptive processing of intracranial electroencephalogram signals are realized; a multi-electrode assembly is adopted, each assembly is provided with a plurality of contacts, the limitation of traditional single-point collection is broken through, different nerve areas are covered through the spatially distributed contact layout, and the focus positioning capacity is improved; the acquisition module effectively eliminates power supply ground wire interference and electromagnetic noise by using a differential amplification and common-mode rejection technology, and eliminates power frequency interference by combining band-pass and notch filtering to ensure the quality of an original signal.
Owner:HANGZHOU NUOWEI MEDICAL TECH CO LTD

Diabetic retina image classification method and system based on deep learning

The invention discloses a diabetes retina image classification method and system based on deep learning, and relates to the technical field of image classification, and the specific steps are as follows: collecting and preprocessing a retina image data set, and constructing a training data set; constructing an initial image classification model based on a deep neural network, and performing iterative training on the initial image classification model by using the training data set to obtain an image classification model; the initial image classification model takes a pre-trained OfficientNet network as a backbone network, and integrates a feature pyramid network structure, a lesion attention module and a classification module; and obtaining a to-be-classified image, preprocessing the to-be-classified image, inputting the preprocessed to-be-classified image into the image classification model, and outputting a classification result. According to the method, the dependence of the model on a specific data source is reduced by using a data enhancement strategy, the diagnostic performance and stability of the model on unseen retina images are improved, and the universality of clinical application is enhanced.
Owner:ZHEJIANG NORMAL UNIV

Osteoporosis prediction method and system based on centrum CT image

The invention provides an osteoporosis prediction method and system based on a centrum CT image, and the method comprises the steps: obtaining a patient centrum CT image, and carrying out the preprocessing of the image, and obtaining standardized three-dimensional voxel data; performing spatial resampling on the original data to a uniform resolution; constructing a hierarchical feature extraction network for centrum bone structure perception, and designing a non-uniform sampling mechanism for centrum density distribution; constructing an intervertebral biomechanical conduction diagram network; designing an osteoporosis specific loss function; and outputting a grading prediction result containing confidence, generating probability distribution of each grade through a softmax function, and generating a visual thermodynamic diagram of the lesion area. Through time sequence consistency constraint, the system can analyze image changes of the same patient at different time points and evaluate the treatment effect and the disease progress. The dynamic monitoring ability provides a powerful tool for long-term management of chronic osteoporosis, and is helpful for timely adjustment of treatment schemes and improvement of prognosis of patients.
Owner:NANJING WANGSHI INTELLIGENT TECHNOLOGY CO LTD

Endoscope image intelligent evaluation method for ulcerative colitis

The invention relates to an intelligent endoscope image evaluation method for ulcerative colitis, and the method comprises the steps: synchronously collecting video streams and three-dimensional point cloud data of a colonic mucosa through an endoscope system equipped with a structured light depth sensor, and constructing a three-dimensional coordinate system based on a colon anatomy trend; based on the three-dimensional point cloud data, constructing a complex topological structure on the surface of the colonic mucosa, and calculating a continuous homology feature set of the lesion area; and based on the persistent homology feature set, constructing a multi-scale graph neural network model of ulcerative colitis and Crohn disease specificity. By implementing the scheme, the structural and topological modeling of the colon mucosa lesion area can be realized, and the morphological characteristic difference between ulcerative colitis and Crohn's disease can be effectively captured. The multi-scale graph neural network fuses macroanatomical segmentation and micropathology features, efficient distinguishing of continuous and jumping lesions is achieved, finally, an intelligent and visual endoscope evaluation report is generated, and the accuracy and real-time performance of auxiliary diagnosis in an operation are improved.
Owner:SHENZHEN ZRT CO LTD

Delivery plan evaluation system

System and methods are described for developing a delivery plan for a pulsed field ablation device for treating an arrhythmia. A method runs a lesion development simulation based on cardiac characteristics and a treatment plan that specifies a delivery plan and a target location to generate a simulated lesion having lesion characteristics. The method initializes a three-dimensional (3D) mesh representing a heart based on cardiac characteristics. The vertices of the 3D mesh are associated with cardiac tissue characteristics with some of the associated with cardiac tissue characteristics representing an arrhythmia source. The method adjusts the cardiac tissue characteristics of vertices of the 3D mesh to reflect the effect of an ablation resulting in formation of the simulated lesion. The method runs a lesion evaluation simulation based on the 3D mesh with the adjusted cardiac tissue characteristics to determine whether the simulated lesion would be effective at treating the arrhythmia.
Owner:THE VEKTOR GRP INC

Colon polyp segmentation method based on multi-frequency guiding attention network

The invention relates to a colon polyp segmentation method based on a multi-frequency attention guiding network, and the method comprises the steps: inputting a polyp image into a backbone network through constructing the multi-frequency attention guiding network, and extracting the feature information of different layers; a multi-frequency attention guiding module is constructed to obtain high-frequency edge details and a low-frequency global structure by means of partial features, and boundary features are optimized by combining a feature enhancement space attention module. Further, an iteration content guiding attention mechanism is introduced, and attention distribution is dynamically adjusted according to different areas, especially for lesion areas with fuzzy boundaries and complex forms. According to the method, the limitation of the polyp when the boundary is fuzzy and the form is complex is overcome, a multi-stage loss and output aggregation strategy is adopted in training, and high-precision recognition and segmentation of the polyp area are achieved.
Owner:GUILIN UNIV OF ELECTRONIC TECH

AI-based lung perfusion evaluation system

The invention relates to the technical field of lung perfusion, in particular to an AI-based lung perfusion evaluation system, which comprises an image quality screening module, a blood vessel positioning analysis module, a blood flow velocity measurement module, a blood vessel anomaly analysis module and an anomaly response module, and is characterized in that the image quality screening module monitors the pixel density of an image and the variation amplitude of color gradient. According to the method, through real-time image definition evaluation and screening, the image selection process is optimized, it is ensured that all the images used for analysis reach the high-quality standard, the gray level change and the edge contour of the blood vessel are automatically calculated, the potential lesion area is accurately positioned and marked, more detailed blood vessel structure analysis is provided, and the accuracy of blood vessel analysis is improved. In addition, the system can rapidly analyze the speed deviation of the blood vessel segment, timely identify the abnormal blood flow, effectively improve the judgment speed of diseases such as pulmonary embolism or pulmonary hypertension, enhance the efficiency of coping with emergency medical conditions through automatic abnormal detection and recording, improve the accuracy and speed of judgment, and support more effective clinical decisions.
Owner:THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV

Tumor space-occupying brain network neural image alignment method based on multi-modal fusion

The invention discloses a tumor space-occupying brain network neural image alignment method based on multi-modal fusion, and belongs to the technical field of medical image processing and artificial intelligence crossing. The method comprises the following core steps of multi-modal image heterogeneous feature decoupling, tumor occupation deformation field modeling, functional network topological structure maintenance, cross-modal feature adversarial alignment, dynamic deformation constraint optimization and clinical interpretability verification, and construction of a three-dimensional non-rigid registration network based on a double attention mechanism. And differential homeomorphic mapping of a tumor focus area and normal brain tissue is realized through the cascaded spatial transformation module. Aiming at the problems of insufficient multi-modal feature alignment and brain network topology distortion in the prior art, the invention provides a function connection constrained cross-modal fusion strategy, a graph convolution network is adopted to encode resting state function connection features, and network node displacement caused by tumor occupation is dynamically corrected in combination with deformable convolution and a bidirectional feature competition mechanism; a space consistency loss function based on white matter fiber bundle tracing is designed, and through diffusion tensor imaging feature guide structure-function bimodal joint optimization, the problems of insufficient registration precision in a focus area and whole brain network connection distortion of a traditional method are solved. Experiments show that the registration precision of the method in glioma cases reaches 0.82 mm and is improved by 37% compared with that of a traditional method, and dissection-function consistency of functional network reconstruction around tumors is remarkably improved.
Owner:UNIV OF ELECTRONICS SCI & TECH OF CHINA

Pathological image segmentation method and device based on category labels and readable storage medium thereof

The invention provides a pathology image segmentation method and device based on category labels and a readable storage medium, and the method comprises the steps: segmenting a full-view digital pathology (WSI) image, and extracting a feature map containing local textures and global semantics through a ResNet, ViT or a pathology-dedicated pre-training large model UNI; calculating the contribution degree of an image block to a classification result through an attention mechanism, and extracting the actual influence of features on a classification decision in combination with gradient analysis; and fusing the two weights by adopting a sorting weighting strategy, generating a lesion area mask through Gaussian blur and Otsu method threshold segmentation, and finally superposing the lesion area mask to an original image to output an interpretable segmentation result. According to the method, weak supervision segmentation can be realized only through slice-level labels, the labeling cost is remarkably reduced, the positioning precision is improved through complementary fusion of attention and gradient information, a visual and visual lesion area is generated, the model transparency and clinical practicability are enhanced, and the method is suitable for various pathological image analysis scenes.
Owner:SHENZHEN SHENGQIANG TECH

Characterization of lesions via determination of vascular metrics using MRI data

ActiveUS20250272828A1Image enhancementMagnetic measurementsDynamic contrast-enhanced MRIMalignancy
Disclosed are approaches to non-invasively characterize a tumor or other lesion in a region of interest (ROI) based on various analyses of magnetic resonance imaging (MRI) data. The MRI data may correspond to ultrafast dynamic contrast enhanced MRI (DCE-MRI) and high spatial resolution DCE-MRI scans, and diffusion-weighted MRI (DW-MRI) scans of the ROI. Vasculature metrics may be determined, and tumor-associated blood flow velocity and / or tumor interstitial pressure may be obtained using the vasculature metrics as inputs to a computational fluid dynamics model. A combination of morphological vascular metrics and functional vascular metrics may be used to characterize the tumor. Malignancy, aggressiveness, treatment response, and other features of tumors or other lesions, in the breast or other regions of a patient, may be characterized through disclosed analyses of MRI data.
Owner:UNIVERSITY OF CHICAGO +1

Splicing method and splicing device for digestive tract magnetic control capsule endoscope images

The invention provides a splicing method and a splicing device for a magnetic control capsule endoscope image of a digestive tract. The method comprises the following steps: screening out a candidate lesion area image sequence from an original alimentary canal image sequence collected by a magnetic control capsule endoscope; preprocessing the candidate lesion area image sequence to obtain a preprocessed candidate lesion area image sequence; performing feature extraction on the preprocessed candidate lesion area image sequence based on an OfficientLoFTR improved model, further performing feature matching on the preprocessed candidate lesion area image sequence to obtain matched feature point pairs, and performing image registration processing on each image of the preprocessed candidate lesion area image sequence according to the matched feature point pairs to obtain a pre-processed candidate lesion area image sequence; the improved model can improve the accuracy of feature detection and matching, a good foundation is laid for subsequent image registration and image fusion, image registration can be carried out by combining global homography transformation and local thin plate spline transformation, and the problem of non-rigid deformation is solved.
Owner:ZHEJIANG SHITONG ROBOT TECH CO LTD

Application of RcWRKY31 gene in enhancing resistance of Chinese rose to gray mold

The invention discloses an application of an RcWRKY31 gene in enhancing the resistance of Chinese rose to gray mold. The nucleotide sequence of the RcWRKY31 gene is as shown in SEQ ID NO. 1. The RcWRKY31 gene is silenced and overexpressed in petals which are good in Chinese rose growth state and free of botrytis cinerea infection, and research results show that the petals treated by the silent RcWRKY31 gene are larger in scab area and lower in resistance to botrytis cinerea; the resistance of petals treated by overexpression of the RcWRKY31 gene to gray mold is enhanced.
Owner:FLOWER RES INST OF YUNNAN ACAD OF AGRI SCI

Myopic macular traction lesion grading method and system

The invention relates to the technical field of medical image classification, in particular to a myopic macular traction lesion grading method and system. The method comprises the following steps: taking a convolutional neural network, a direction perception attention module and a classifier which are connected in sequence as an MTM classification model; a direction perception attention module extracts weight information of a space position through a direction perception space attention module, and a channel attention module is used for extracting weight information of a channel; an MTM classification model is used as a backbone network, direction perception attention modules and auxiliary branches which are connected in sequence are arranged after first M-1 feature coding stages of a convolutional neural network, and a self-distillation model is constructed; by combining a structural knowledge distillation strategy based on multi-stage feature fusion, a historical knowledge distillation strategy based on a linear growth mechanism and a category perception comparison learning strategy, multi-angle feature information interaction is fully utilized, multi-angle information collaborative optimization is realized, and the classification precision of the MTM classification model is effectively improved.
Owner:SUZHOU UNIV

Control method, system and equipment of throat intelligent surgical robot and medium

The invention discloses a control method, system and equipment of an intelligent throat surgical robot and a medium. According to the scheme, a three-dimensional tissue model is constructed according to visual image data, laser imaging data and tomography image data; determining lesion data according to the historical lesion data and the tomography image data, superposing the lesion data and the three-dimensional tissue model, and determining a target operation model; determining prediction trajectory data according to the tomography image data and the physiological motion data; planning a path according to the predicted trajectory data, the target operation model and the constraint condition, and controlling the operation robot to perform an operation according to the planned path; through multi-modal data fusion, a three-dimensional tissue model is established to improve the surgical accuracy; the data are analyzed to determine the lesion direction, the motion trail of the organ tissue is predicted, the three-dimensional tissue model is integrated for path planning, the interference of physiological activities of the organ tissue on the operation is avoided, and the safety of the operation is improved. The embodiment of the invention can be widely applied to the field of intelligent robots.
Owner:THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIV