74 results about "Cardiac Ablation" patented technology

The title of the invention is "using blood conductivity to control cardiac ablation". Methods and systems provide lesion size assessment for ablation in tissue, such as cardiac tissue. The lesion size assessment is based on parameters including blood conductivity, hot spot temperature, catheter tip temperature, and current data of radio frequency (RF) ablation energy used, such as power, duration, temperature, irrigation, and contact force.

Techniques for catheter path planning for a cardiac ablation procedure to treat an arrhythmia of a patient are provided. One technique receives data that includes a three-dimensional (3D) image of the heart of the patient and an electrocardiogram collected from the patient and that includes a catheter specification. The technique applies a path planning system to the 3D image, a location (e.g., source location or target location), and the catheter specification to generate a candidate path from a starting point to a target point that is based on the location. The technique outputs an indication of the candidate path to help inform the ablation procedure to treat the arrhythmia of the patient.

A medical device includes an elongate hollow shaft having a shaft proximal end, a shaft distal end, and a lumen extending along the elongate hollow shaft. A handle is disposed at the shaft proximal end. A connector assembly having a connector assembly proximal end and a connector assembly distal end, the connector assembly proximal and distal ends being opposite ends of the connector assembly. An expandable frame is detachably disposed at the connector assembly distal end, the expandable frame including a plurality of interconnected members formed of an electrically conductive material, wherein the interconnected members in a first portion of the expandable frame are coated with a dielectric layer, and wherein the interconnected members in a second portion of the expandable frame are uncoated and configured as an electrode region of the expandable frame.

The present disclosure relates to a catheter (C) for ablating a tissue comprising: at least two ablation electrodes (A1, A2) configured for applying a pulse of an electrical energy to the tissue: wherein the catheter is configured such that, in an ablation position of the catheter, the ablation electrodes (A1, A2) contact the tissue along a main axis (z) of the catheter.

A force sensor assembly for use in the field of cardiac ablation, for the ablation-based treatment of atrial fibrillation and other cardiac arrhythmias. Various embodiments of the disclosure are directed to a catheter distal force sensor for measuring catheter tip-to-endocardial wall force by measuring displacement of irradiation patterns sensed with a two-dimensional imaging sensor. The disclosed devices sense an array of irradiation pattern characteristics, including changes in size and location of irradiation shapes of the irradiation pattern. In some embodiments, multiple irradiation spots are tracked with the two-dimensional imaging sensor to infer the components of a reaction force vector acting the force sensor assembly. The disclosed force is designed to accommodate typical catheter tip dimensions, the outer diameter of these usually being less than or equal to 3 mm.

A system that enables safe cardiac pulsed field ablation by using multiple types of sensors on a patch to detect and cross-check that the heartbeat is in a safe phase to receive an ablation pulse. The patch may contain for example any or all of ECG electrodes, PPG sensors, accelerometers, and microphones. The patch may also contain one or more pulse return electrodes for unipolar ablation. A signal analyzer coupled to a pulse generator may receive sensor data from the patch and may analyze this data to determine the heartbeat phase. If data from different sensors are inconsistent, then pulse generation may be disabled as a safety feature. Otherwise, pulses may be enabled when the heartbeat is in a safe phase; for example, pulses may be excluded during the T wave.

The invention relates to the field of cardiac ablation, and provides a pair of pulse ablation forceps which comprises a forceps body and a jaw part, the jaw part is mounted on the forceps body and composed of a fixed forceps arm and a movable forceps arm parallel to the fixed forceps arm, the forceps body comprises a sliding groove, the fixed forceps arm is fixedly connected to the far end of the sliding groove, and the movable forceps arm gets close to or away from the fixed forceps arm along the sliding groove. In the extending direction of the jaw part, from the far end to the near end, n first electrodes are arranged on the movable clamp arm, n + 1 second electrodes are arranged on the fixed clamp arm, and n is larger than or equal to 2; in the direction perpendicular to the extending direction of the fixed clamp arm, the projection of each first electrode on the fixed clamp arm is located between the two second electrodes; all the first electrodes are arranged outside the sliding groove, and at least one part of the (n + 1) th second electrode is arranged in the sliding groove. According to the pulse ablation forceps, the situation of ablation leakage is avoided, meanwhile, electric arcs cannot be generated, and the ablation effect is improved.

Various aspects of the present disclosure are directed towards apparatuses, systems, and methods for electroporation ablation. The electroporation ablation catheter may include an electrode assembly comprising one or more electrodes configured to generate electric fields in target tissue in response to a plurality of electrical pulse sequences delivered in a plurality of therapy sections, and an ultrasound transducer configured to generate a first set of ultrasound signals during a first electrical pulse sequence of the plurality of electrical pulse sequences and generate a second set of ultrasound signals after an end of the first electrical pulse sequence and before a beginning of a second electrical pulse sequence, the second electrical pulse sequence being an electrical pulse sequence subsequent to the first electrical pulse sequence.

Cardiac ablation catheters include an outer balloon positioned at a distal end of the catheter and configured to have an inner balloon disposed therein. The outer balloon is inflated with a first fluid that has a temperature less than 100 degrees Celsius, while the inner balloon is inflated with heated vapor. An area of contact between the two balloons, comprising a surface area less than the total surface area of either balloon, creates a hot zone for ablating cardiac tissue through the transfer of thermal energy from the contact area to the cardiac tissue.

A gap between a plurality of ablation sites in a heart that hinders electrical propagation therethrough is found by projecting the locations of the sites in a 3-dimensional coordinate system onto a simulation plane, identifying a set of shortest 3-dimensional paths that correspond to 2-dimensional connections between pairs of the projected locations of the sites, and reporting a gap as a longest one of the set.

A catheter deploys a flexible electrode that is at least partially made of preformed hydrogel to a target location in order to provide radiofrequency catheter ablation. The catheter stores the flexible electrode, which can be deployed and retracted. The preformed hydrogel is conductive and thus can provide an interface between a conductive metal wire and a target cardiac tissue. Electric energy is applied to the portions of the cardiac tissue target tissue that are the genesis of the errant and abnormal heartbeats via the flexible electrode. The electric energy may create lesions with lower risks of steam pops and tissue perforation.

Systems and methods of automatically controlling, on a graphical user interface used by a physician, display views of an anatomic structure of a patient. Such systems and methods of automatically controlling display views of an anatomic structure of a patient can facilitate visualizing a position of a medical device relative to the anatomic structure during a medical procedure directed to the anatomic structure. In certain implementations, the systems and methods of the present disclosure provide automatic display views of a cardiac catheter relative to a three-dimensional model of a patient's heart cavity during a medical procedure such as cardiac ablation.

The invention is entitled "Breath control during cardiac ablation." The invention discloses a method for invasive cardiac treatment, the method comprising inserting a catheter into a beating heart of a patient who is anesthetically paralyzed and intubated for ventilation via a transvascular path, and temporarily stopping ventilation of the patient after the catheter is inserted. The method comprises moving the catheter between a plurality of locations of myocardial tissue of the heart with the ventilation stopped, and ablating the myocardial tissue of the heart at the plurality of locations with the ventilation stopped.

Systems, apparatuses, and methods for electroporation ablation therapy are disclosed, with a protection device for protecting electronic circuitry, devices, and / or other components from induced currents and voltages generated during a cardiac ablation procedure. A system can include an ablation device near cardiac tissue of a heart. The system can further include a signal generator configured to generate a pulse waveform, where the signal generator coupled to the ablation device and configured to repeatedly deliver the pulse waveform to the ablation device in synchrony with a set of cardiac cycles of the heart. The system can further include a protection device configured to suppress induced current and voltage in an electronic device coupled to the protection device.

The invention discloses a pulsed electric field ablation system electrode attachment detection method based on a support vector machine, and relates to the technical field of cardiac ablation, and the method comprises the following specific steps: 1, data set collection and preprocessing: recording the current frequency, the impedance amplitude difference and the phase difference between every two adjacent electrodes under different power-on frequencies, step 2, support vector machine SVM training and testing: training the support vector machine SVM through the data set to obtain an SVM nonlinear classifier; and step 3, performing electrode attaching detection. According to the method, the support vector machine SVM is trained through the multiple groups of training set sample data and the corresponding labels, the trained SVM nonlinear classifier is obtained, new data are detected by means of the trained SVM nonlinear classifier, and due to the fact that the SVM has high accuracy for the nonlinear classification problem, the accuracy of the SVM is improved. The contact state of the electrode and the tissue can be accurately judged according to a predicted value output by the trained model, and failure or misjudgment of a model detection result caused by nonlinear change of human tissue impedance is avoided.

In one exemplary mode, an apparatus includes a catheter including an electrode to provide an intracardiac electrogram (IEGM) signal and a signal used to sense impedance, an ablation energy generator configured to conduct ablative energy to the electrode of the catheter based on user input, a controller configured to sample the IEGM signal from the electrode before and after a given ablation, and sense impedance between the electrode and tissue, and a processor configured to compare the sensed impedance with a TPI threshold to determine a contact status of the electrode with respect to the tissue, render to a display an indication of the determined contact status, compute a change in the IEGM signal due to the given ablation, and adjust the TPI threshold for subsequent ablations based on the computed change in the IEGM signal due to the given ablation of the tissue with the electrode.

Various aspects of the present disclosure are directed to devices, systems, and methods that may include a cardiac ablation catheter. The cardiac ablation catheter may include a handle, a elongate shaft, and a distal assembly that includes a tip electrode, a ring electrode, and an insulator preform.

A medical device includes an elongate hollow shaft having a shaft proximal end, a shaft distal end, and a lumen extending along the elongate hollow shaft. A handle is disposed at the shaft proximal end. A connector assembly having a connector assembly proximal end and a connector assembly distal end, the connector assembly proximal and distal ends being opposite ends of the connector assembly. An expandable frame is detachably disposed at the connector assembly distal end, the expandable frame including a plurality of interconnected members formed of an electrically conductive material, wherein the interconnected members in a first portion of the expandable frame are coated with a dielectric layer, and wherein the interconnected members in a second portion of the expandable frame are uncoated and configured as an electrode region of the expandable frame.

The animated GUI displays the detection results of multiple electrodes on a ring-shaped catheter contacting adjacent tissue during cardiac ablation procedures using transparent spheres of various sizes and shapes surrounding each electrode. The design is characterized by a combination of the shape, position, and contrast of graphical elements. The design is displayed in grayscale. Protection is not sought for the specific color of the design. The red-colored area within the dashed lines in the design drawings indicates portions of the graphical user interface that do not form part of the design sought to be registered. Figure 4.1 shows the first image in a sequence of a graphical user interface for a display screen or portion thereof. Figure 4.2 shows the second image. Figure 4.3 shows the third image. Figure 4.4 shows the fourth image. Figure 4.5 shows the fifth image. Figure 4.6 shows the sixth image. Figure 4.7 shows the seventh image. 4.1) Front view; 4.2) Front view; 4.3) Front view; 4.4) Front view; 4.5) Front view; 4.6) Front view; 4.7) Front view

The invention discloses application of an Fn1-PPARbeta / delta signal channel related to a cardiac liver disease. The cardiac liver disease model is constructed according to the conditions that the liver development of young individuals is delayed due to heart injury and both adult and young individuals have serious fatty livers. In the model, the Fn1 protein level in the heart and blood is obviously increased compared with the normal level. Based on a zebra fish heart ablation means, after heart ablation injury, the heart specific knock-down Fn1 can lead to reduction of the Fn1 protein level in blood and alleviation of liver development retardation and fat deposition. Through the screening of transcriptomics, the PPARbeta / delta protein in the liver is found to be a potential downstream effect factor of Fn1. The liver specific overexpression PPARbeta / delta protein can significantly relieve abnormal phenotypes such as liver fat deposition caused by heart injury, and after the liver specific knock-down PPARbeta / delta protein, the protection effect of knock-down Fn1 on the liver disappears under the condition of heart injury. Therefore, the Fn1 protein and the PPARbeta / delta protein can be used as targets for preventing and treating the cardiac liver injury, and are used for preparing medicines for improving the cardiac liver injury, so that a new way is provided for treating the cardiac liver disease.

Systems, devices, and methods for electroporation ablation therapy are disclosed herein, with a cinch device for positioning an ablation catheter relative to tissue during a cardiac ablation procedure. In some embodiments, a distal end of a first device may be advanced into a proximal end of a first lumen of a second device. The first device may be advanced from a distal end of the first lumen and the first device may be looped around tissue of a patient. The first device may be advanced into a distal end of a second lumen of the second device. The distal end of the first device may be advanced from a proximal end of the second lumen. The proximal and distal ends of the first device may be advanced away from a proximal end of the second device to increase contact between the first device and the tissue.

Systems, devices, and methods for electroporation ablation therapy are disclosed with protection devices for isolating isolation electronic circuitry, devices, and / or other components from a set of electrodes during a cardiac ablation procedure. A system can include a first set of electrodes disposable proximate to cardiac tissue of a heart and a second set of electrodes disposable in contact with patient anatomy. The system can also include a signal generator configured to generate a pulsed waveform, where the signal generator is coupled to the first set of electrodes and configured to repeatedly deliver the pulsed waveform to the first set of electrodes. The system can also include a protection device configured to selectively couple and decouple electronic devices from the second set of electrodes.

The present invention discloses a cardiac ablation needle, and the electrode needle body is disposed through the outer sleeve. The distal end of the electrode needle body extends out of the outer sleeve. A cavity is formed in the middle of the electrode needle body, and a discharge hole is formed at the distal end of the electrode needle body. The other end of the discharge hole communicates with the cavity, and hydrogen peroxide is injected inside the cavity. It solves the problem in the prior art that for patients with a relatively large size of ventricular septal hypertrophy, the cardiac ablation needle cannot meet the requirement of accurately adjusting the position of the ablation needle after one ablation and fulfilling the function of multiple ablations. This cardiac ablation needle forms a cavity inside the electrode needle body. The hydrogen peroxide in the cavity plays a role in controlling the temperature of the electrode needle body. Secondly, through the oxidation-reduction reaction of hydrogen peroxide, a small amount of the generated oxygen enters the ventricular septal position, meeting the purpose of ultrasonic imaging, accurately imaging the position of the electrode needle body, facilitating the precise adjustment of the ablation position of the ablation needle, fulfilling multi-position ablation with one puncture, and improving the treatment effect.

The invention discloses a cardiac ablation planning method and system based on multi-modal data fusion. The method comprises the following steps: collecting multi-source heterogeneous cardiac function data, unifying coordinates, and obtaining registered cardiac function data; extracting dynamic features from the registered cardiac function data; performing cross-modal attention fusion on the dynamic features to obtain a fusion feature map; predicting the ablation possibility of each voxel on the basis of the fused feature map to obtain an ablation target point probability map generation model; dissection boundary constraint conditions are set for the ablation target point probability graph generation model, and a safe ablation target point probability graph is obtained; and constructing an ablation path energy optimization model, and calculating an ordered ablation point sequence through a path planning algorithm. The system comprises a registration module, a dynamic feature extraction module, a feature fusion module, an ablation target point probability graph generation module, a constraint module and a path planning module. According to the method, automatic and quantitative target point probability prediction can be realized, and the optimal ablation point sequence can be automatically calculated.

The present invention belongs to the technical field of medical devices, and particularly relates to a cardiac ablation pulsed electric field control device, a control method and an operation method. Among them, the cardiac ablation pulsed electric field control device includes a pulse generator and an electrode connected to each other; the electrode includes: a catheter electrode with a ring electrode at the distal end, which is connected to the positive electrode of the pulse generator. A body surface electrode, which is a strip-shaped electrode and is connected to the negative electrode of the pulse generator. The present invention adopts two groups of electrodes, namely a body surface electrode and a catheter electrode, to improve the penetration depth of the pulsed electric field and the efficiency of electroporation.

An apparatus includes a shaft, the shaft including a plurality of stepped sections along the length of the shaft. The apparatus further includes a plurality of electrodes disposed along the length of the shaft, each electrode characterized by a geometric aspect ratio of the length of the electrode to the outer diameter of the electrode. Each electrode is located at a different stepped section of the plurality of stepped sections of the shaft and includes a set of leads. Each lead of the set of leads is configured to attain an electrical voltage potential of at least about 1 kV. The geometric aspect ratio of at least one electrode of the plurality of electrodes is in the range between about 3 and about 20.

The utility model belongs to the field of microwave ablation electrodes, and particularly relates to a microwave ablation electrode for cardiac ablation, which comprises an ablation tube, a wire inlet tube is fixedly connected to the upper end of the ablation tube, a damping mechanism is arranged on the wire inlet tube, and a handle frame is fixedly connected to the upper portion of the right end of the ablation tube. A turnover frame is hinged to the interior of the handle frame, and a supporting frame is arranged on the outer side of the turnover frame. The supporting frame, the overturning frame, the first spring and other structures are additionally arranged in the handle frame, in the holding process, fingers can be inserted between the supporting frame and the handle frame, and then the supporting frame is pushed through the elastic force of the first spring to extrude the fingers between the supporting frame and the handle frame; therefore, the handle frame can be limited on the outer sides of the fingers through the elastic force of the first spring, the device can be effectively prevented from being actively held, the fatigue degree of the fingers is reduced, and the device can be more stably held.

Systems, devices, and methods for electroporation ablation therapy are disclosed, with a protection device for isolating electronic circuitry, devices, and / or other components from a set of electrodes during a cardiac ablation procedure. A system can include a first set of electrodes disposable near cardiac tissue of a heart and a second set of electrodes disposable in contact with patient anatomy. The system can further include a signal generator configured to generate a pulse waveform, where the signal generator coupled to the first set of electrodes and configured to repeatedly deliver the pulse waveform to the first set of electrodes. The system can further include a protection device configured to selectively couple and decouple an electronic device to the second set of electrodes.

The invention provides a computer readable storage medium and a pulse ablation system, when a program on the medium is executed, the following steps are executed: controlling a pulse generator to generate pulses at least according to a preset relationship among a pulse width D, a current I in a pulse circuit and a pulse frequency f in each cardiac cycle; the preset relation is I * f * lt; h; # imgabs0 # U is the voltage in the pulse circuit, S1 is the surface area of a head electrode of the ablation catheter, S2 is the sum of the surface areas of all ring electrodes of the ablation catheter, L is the distance between the head electrode and a preset plane, the plane is set to be perpendicular to the axis of the ablation catheter, the distances between the preset plane and the two ring electrodes used for forming the negative electrode are equal, and n1 and n2 are constants larger than 1; h is a constant. The computer readable storage medium is applied to the pulse ablation system, so that when the pulse generator generates pulses and is applied to cardiac ablation, generation of microbubbles and sparks can be reduced, and stimulation to the phrenic nerves is reduced under the condition that the ablation catheter is close to the phrenic nerves.

Aspects of the present disclosure relate to devices, systems, and methods that may include a cardiac ablation catheter. The cardiac ablation catheter may include a handle, an elongate shaft, and a distal assembly including a tip electrode, a ring electrode, and an insulator preform.