205 results about "Cryoablation" patented technology

In an embodiment, a cryoablation probe includes a shaft, where the shaft has a supply tube, a return tube surrounding the supply tube, an insulated portion, wherein a vacuum circuit runs through the insulated portion between the return tube and an insulating shaft, and an expansion chamber extending distally to the insulated portion. The probe further includes a distal tip configured to seal a distal end of the return tube. The distal tip has a tip portion extending distally from the distal end of the return tube and a plug portion configured to be inserted inside of the return tube. The probe includes a compressive element surrounding the return tube and the plug portion of the distal tip, configured to seal the distal tip to the return tube.

The invention belongs to the technical field of medical instruments, and particularly relates to a cryoablation catheter and an ablation system.The cryoablation catheter comprises an inner catheter body and an outer catheter body, the outer catheter body is coaxially arranged on the outer side of the inner catheter body in a sleeving mode, and the inner catheter body is configured to be of a multi-cavity structure; the multiple plugging assemblies are arranged on the outer side of the inner catheter; wherein in the initial state, the multiple plugging assemblies and the inner catheter are located in the outer catheter, and in the working state, the multiple plugging assemblies and the inner wall of the intestinal tract jointly form an ablation closed space. The cryoablation catheter is guided to a target position through the guide wire, the closed ablation space is formed through cooperation of the plugging assembly and the inner wall of the cavity, a freezing medium is input into the closed ablation space to conduct cryoablation on the inner wall of the cavity, an available treatment scheme is provided for patients suffering from type 2 diabetes, obesity or other cavity lesions, and meanwhile the treatment effect is improved. The device has the advantages of small trauma, less pain of patients, low surgical risk and the like.

The invention relates to the technical field of medical instruments, in particular to a cryoablation needle based on radio frequency rewarming, the medical instrument comprises a needle body, a capillary catheter, a first air inlet pipe, a second air inlet pipe, a needle tube, an insulating tube, a vacuum tube and a radio frequency welding wire, and after the needle body on the needle tube is led into tissue by an operator, the needle body is heated to be cooled; the tissue is frozen after air is injected through the first air inlet pipe and the second air inlet pipe to be cooled, then the tissue is rapidly heated under the action of the radio frequency welding line on the needle tube and is inactivated after multiple times of circulation, treatment is completed, meanwhile, internal redundant tissue fluid is automatically and rapidly guided out through the capillary catheter, secondary infection is avoided, and the device is simple in structure and convenient to operate. The problem of treatment of diseased tissues is effectively solved, and the device has good practicability and economical efficiency and is beneficial to popularization and use of equipment.

The invention relates to a cryoablation system, a cryoablation catheter and a control method of the cryoablation catheter. The cryoablation catheter comprises a slender body, an expandable assembly and a temperature measuring assembly, the expandable assembly is arranged at the far end of the slender body, and the expandable assembly can block a vein mouth when in an expanded structure; the slender body comprises an outer tube and a main body tube, the outer tube and the main body tube define an airflow channel, the main body tube is provided with a first conveying channel, the airflow channel is communicated with the expandable assembly, and the first conveying channel penetrates through the main body tube and is used for conveying mild liquid to veins; the temperature measuring assembly is arranged on the expandable assembly and can detect the temperature of the vein mouth so as to judge the effectiveness of plugging of the expandable assembly. Thus, the temperature measuring assembly on the expandable assembly is used for measuring temperature changes to judge the blocking state, the usage amount of contrast agents and X-rays can be reduced, the specific leakage position can be judged, ablation treatment can be conveniently carried out in the later period, and the treatment effect is guaranteed.

A cryoprobe includes a needle defining an internal cavity, a cryogen conduit positioned in the internal cavity, an adjustable insulating sleeve positioned in the inner cavity radially outward of the cryogen conduit, and a heater configured to heat the needle to predetermined temperature.

Disclosed are a freezing and electric ablation combined ablation system, an ablation needle, and a control method. The ablation system (100) comprises: a control module (150), and a freezing module (112) and an electric ablation module (121) connected thereto. The freezing module (112) and the electric ablation module (121) are connected to the ablation needle. The freezing module (112) freezes the target tissue to below 0 °C by means of a cryoablation needle, and performs cryoablation and / or freezing fixation and / or freezing anesthesia on the target tissue (240); the electric ablation module (121) is at least connected to two electrodes (11) insulated from each other, the at least one electrode part is located in a shallow freezing area (210) or can be converted into a deep freezing area (220) of the shallow freezing area, and the electric ablation module (121) performs electric ablation on the target tissue (240) by means of the electrodes (11). The freezing and electric ablation synergistically act on the same target tissue (240). By selectively controlling the temperature of the freezing area, effective electric ablation is carried out on the outer edge range of the freezing area.

The invention discloses an adjustable targeting area type cryoablation needle with a heating function and a novel refrigerant hole structure, and belongs to the technical field of interventional medical instruments, the adjustable targeting area type cryoablation needle comprises a needle rod, a vacuum wall, a J-T groove, a J-T groove sleeve and an adjusting device; the vacuum wall is sleeved with the needle rod, the area from the far end of the needle rod to the far end of the vacuum wall is a target area, the area of the vacuum wall is a vacuum heat insulation area, and the vacuum wall comprises a vacuum wall outer pipe and a vacuum wall inner pipe; the J-T groove is formed in the vacuum wall inner tube, the far end of the J-T groove is located in the far end of the needle rod, and a side hole is formed in the side wall of the J-T groove; the J-T groove is sleeved with the J-T groove sleeve; the J-T groove sleeve and the vacuum wall are fixed together through a connecting piece and can move synchronously and axially. And the adjusting device is used for adjusting the length of the target area. By innovatively designing the arrangement of the cooling ablation air holes and the heat conduction isolation layer, more accurate control over the cryoablation range is achieved, and the safety and effectiveness of cryoablation interventional therapy are improved.

The embodiment of the utility model discloses a cryoablation catheter and a cryoablation system. The cryoablation catheter comprises a transmission assembly, an intervention assembly and an ablation assembly which are sequentially connected and communicated, the transmission assembly conveys a variable-temperature working medium into the ablation assembly through the intervention assembly for ablation operation, and the variable-temperature working medium flows back from the intervention assembly and the transmission assembly in sequence after being subjected to heat exchange through the ablation assembly and is output; the transmission assembly comprises a transmission liquid inlet pipe which is connected and communicated with the intervention assembly; the transmission pressure relief pipe is arranged outside the transmission liquid inlet pipe in a sleeving mode to form a pressure relief channel, a pressure relief hole is formed in the transmission liquid inlet pipe, and the pressure relief hole communicates with the transmission pressure relief pipe; the transmission air return pipe is connected and communicated with the intervention assembly, and the transmission pressure relief pipe is sleeved with the transmission air return pipe to form an air return channel. According to the cryoablation catheter, the pressure relief hole is formed, so that the freezing medium can be continuously, rapidly and stably conveyed into the ablation assembly from the intervention assembly to be pre-cooled, the pre-cooling temperature is rapidly reached, the pre-cooling efficiency is effectively improved, the pressure relief hole is formed in the conveying liquid inlet pipe, and the machining difficulty and the machining cost are reduced.

A probe for performing a cryoablation treatment that includes a handle with a heater configured to heat a fluid and a needle connected to the handle and extending therefrom to a distal end. The needle includes a pathway configured to move the fluid from the handle toward the distal end to heat the needle.

A system and method are presented for treating targeted tissue using cryoablation. A linear endobronchial ultrasound (EBUS) device is positioned adjacent the targeted tissue and is used to guide a percutaneously inserted cryoprobe into the targeted tissue. The EBUS device is partially rotated in order to create multiple image slices that are combined together. To overcome the acoustic shadow created by the ice ball, a 3D model is created of the ice ball based on the locations identified on visible portion of the ice ball's peripheral surface. These locations are mirrored across an axis defined for the cryoprobe to define an approximate location for the hidden, non-visible periphery. This model is then displayed along with the location of the targeted tissue and an indication of the killing zone of the ice ball defined by a selected isotherm.

A method of positioning a cryoprobe includes receiving a cryoprobe repositioning selector indicating a desire to reposition a cryoprobe relative to a target tissue; obtaining cryoprobe operating information from one or more sensors positioned in the cryoprobe, wherein the cryoprobe operating information characterizes one or more operating parameters of the cryoprobe; energizing a heater in the cryoprobe to heat a tip of the cryoprobe to a predetermined cautery temperature threshold; and displaying a cautery indicator when the tip of the cryoprobe is greater than or equal to the cautery temperature threshold.

The present application relates to a cryoablation system, a cryoablation catheter (10) and a control method therefor. The cryoablation catheter (10) comprises an elongated body (100), an expandable assembly (200) and a temperature measuring assembly (300). The expandable assembly (200) is arranged at the distal end of the elongated body (100); and when the expandable assembly (200) is in an expanded configuration, the expandable assembly can block a venous orifice portion (510). The elongated body (100) comprises an outer tube (110) and a main body tube (120), the outer tube (110) and the main body tube (120) enclosing an airflow channel (130); the main body tube (120) is provided with a first delivery channel; the airflow channel (130) is in communication with the expandable assembly (200); and the first delivery channel penetrates through the main body tube (120) and is used for delivering a mild liquid to a vein (50). The temperature measuring assembly (300) is provided on the expandable assembly (200) and can measure the temperature of the venous orifice portion (510), so as to determine the effectiveness of the blocking achieved by the expandable assembly (200).

The invention discloses an ablation system and method for a cardiovascular balloon. The system comprises a multi-section temperature control balloon, a cooling rate control module, a flow control module, a pressure adjusting module, an intelligent feedback control module and a safety protection module. The method comprises the following steps: initializing a multi-section temperature control balloon, and deploying a cooling rate control module, a flow control module, a pressure regulation module, an intelligent feedback control module and a safety protection module; the initial temperature Ti, 0 of each section is obtained, the low temperature related to the treatment target is set as the target temperature Ti, target, and the refrigerant flow Fi, 0 and the initial pressure Pi, 0 of each section are initialized; in the real-time control stage of the freezing process, impedance change of cardiovascular tissue is monitored in real time to judge the freezing effect, and various control parameters in the cryoablation process are predicted and adjusted according to constantly changing real-time data; and monitoring whether abnormal temperature change or abnormal pressure change exists between the freezing balloon and the cardiovascular tissue, and if the abnormal temperature change or abnormal pressure change occurs, performing emergency treatment.

The invention discloses a cryoablation needle, and relates to the field of medical equipment, the cryoablation needle comprises a handle, a needle rod, a first air inlet pipe assembly, an air return pipe, a connecting sleeve, a sealing head, a clamping sleeve type compression joint and a second air inlet pipe assembly, the interior of the needle rod is arranged to be of a cavity structure with one end open, and one end of the connecting sleeve is fixedly connected with the handle; the sealing head is arranged on the needle rod in a sleeving mode and is in threaded sealing connection with the inserting end of the connecting sleeve, the air inlet end of the air return pipe is arranged in an air return channel of the connecting sleeve, and the cavity of the needle rod, the air return channel of the connecting sleeve and the air return pipe jointly form an air return channel. The air outlet end of the second air inlet pipe assembly is fixedly connected to the open end of the air return channel of the connecting sleeve and used for being in butt joint with the air inlet end of the first air inlet pipe assembly, and the clamping sleeve type compression connector is fixedly connected to the end of the telescopic structure of the connecting sleeve. The length of the needle rod exposed out of the body of a patient can be adjusted according to actual needs, and meanwhile the connection sealing performance of the needle rod is improved.

Embodiments herein relate to cryoablation systems. In an embodiment, a cryosurgery system includes a closed-loop working fluid circuit configured to contain a working fluid. The system can include a compressor configured to increase the pressure of the working fluid. The system can include a heat exchanger configured to lower the temperature of the working fluid. The system can include a cryoablation probe having a shaft having a supply tube and a return tube surrounding the supply tube. The system is configured so that, after exiting the first heat exchanger, the working fluid will enter the cryoablation probe, travel to the expansion chamber, expand in the expansion chamber at a Joule-Thomson orifice, travel to the cryoablation probe interface via the return tube, exit the cryoablation probe via the working fluid outlet, enter the compressor, and enter the first heat exchanger.

The invention discloses a cryoablation catheter system for pulmonary artery stent internal restenosis, and belongs to the field of medical instruments, the cryoablation catheter system comprises a catheter main body arranged on a guide wire, the catheter main body is provided with a treatment assembly, the treatment assembly is located at the far end of the catheter main body, the catheter main body is provided with a control handle, and the control handle is located at the far end of the catheter main body. The control handle is located at the near end of the catheter body, and the treatment assembly comprises a near-end balloon, a far-end balloon and a freezing balloon. When the near-end balloon and the far-end balloon are simultaneously full, a closed treatment cabin isolated from near-end blood flow and far-end blood flow can be formed in a blood vessel of a target treatment section, the freezing balloon is located in the treatment cabin, the closed treatment cabin thoroughly eliminates the blood flow hot pool effect, cold is prevented from being taken away by the blood flow, and the treatment effect is improved. Freezing energy is intensively acted on a diseased region, so that the ablation efficiency and accuracy are improved; meanwhile, thrombus, tissue debris and whole body blood flow which fall off in the treatment process are isolated, the risk of far-end embolism is reduced from the source, and damage to the blood vessel wall is avoided.

1. The name of the product of this design: cryoablation equipment. 2. Purpose of the product with this appearance design: used in conjunction with a cryoablation catheter for cryoablation treatment of lesions. 3. The design key point of this appearance design product lies in the combination of shape and pattern. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The embodiments of the present invention relate to the field of cryoablation and disclose a cryoablation temperature prediction method, device, electronic device and storage medium, including: constructing a vascular network diagram based on the vascular centerline in the three-dimensional imaging data before the cryoablation operation, the nodes in the vascular network diagram represent the vascular bifurcation points, and the blood edges represent the vascular connection relationship; during the cryoablation process, using a pre-trained temperature prediction model to predict the temperature field of the target sampling point, the temperature prediction model includes a physical information neural network and a graph neural network; the physical information neural network uses the biological heat conduction equation as a constraint condition to predict the temperature field of the target sampling point, and the graph neural network is used to predict the blood perfusion coefficient of each node in the vascular network diagram to determine the blood perfusion coefficient contained in the biological heat conduction equation, which solves the problem of real-time prediction of cryoablation temperature in accordance with physical laws, so that the results conform to physical laws and meet the real-time requirements during the operation.

Embodiments herein relate to cryoablation systems. In an embodiment, a cryosurgery system includes a closed-loop working fluid circuit configured to contain a working fluid. The system can include a compressor configured to increase the pressure of the working fluid. The system can include a heat exchanger configured to lower the temperature of the working fluid. The system can include a cryoablation probe having a shaft having a supply tube and a return tube surrounding the supply tube. The system is configured so that, after exiting the first heat exchanger, the working fluid will enter the cryoablation probe, travel to the expansion chamber, expand in the expansion chamber at a Joule-Thomson orifice, travel to the cryoablation probe interface via the return tube, exit the cryoablation probe via the working fluid outlet, enter the compressor, and enter the first heat exchanger.

The application relates to the technical field of medical devices, in particular to a lung tumor treatment device based on irreversible electroporation and cryoablation, which comprises a single needle for generating high-voltage electric pulses, an ice knife for conveying cold gas medium and a CT display module for displaying CT images in real time, comprises a puncture sleeve, the puncture sleeve is provided with a sliding groove, the single needle and the ice knife are in gap cooperation with the sliding groove; a needle head is detachably connected in the sliding groove, the puncture sleeve is communicated with a conveying pipe, and the puncture sleeve is provided with an outlet for discharging the cold gas medium at one end; the sliding groove is also communicated with a collection mechanism for collecting external tissues, and the collection mechanism is used for collecting the external tissues based on the pushing of the needle head, the single needle and the ice knife; the application is convenient for switching surgical tools, reduces the damage to the surrounding tissues in the body during the treatment of lung ground glass nodules, and guarantees the removal effect of the lung ground glass nodules.

The invention discloses a nerve cryoablation puncture needle suite with a nerve stimulation module, and relates to the technical field of medical equipment, the nerve cryoablation puncture needle suite comprises an ultrasonic easy-to-develop puncture needle main body, and the puncture needle main body is connected with a three-way valve; the probe body is connected with the needle body, the delivery pipe is arranged on the surface of the outer end of the needle body, and the other end of the delivery pipe is communicated with the three-way valve and can be used for drug delivery. After the tail end of the needle core is connected with the nerve stimulation module, current can be quantitatively output, the tip of the needle core can stimulate nerve fibers with the diameters from small to large, nerve sensation or movement reaction can be induced, focus-related nervous tissue can be accurately targeted, tissue specificity in the treatment process is ensured, and accuracy and safety of pain treatment are improved. The refrigerating pipe is arranged at the middle end in the needle body, the vacuum cavity is formed in the inner wall of the needle body, when the refrigerating fluid is vaporized and discharged through the outlet, the refrigerating fluid which is not vaporized completely makes contact with the outlet, the filler is cooled and expands to block the outlet, and the refrigerating fluid is effectively prevented from overflowing at low temperature.

Provided in the present invention is a cryoablation system, which comprises a gas source, a rewarming tubing, a freezing tubing, and an output connector. The rewarming tubing is connected in parallel to the freezing tubing, the freezing tubing comprises a heat exchanger, a working medium flows in from an inlet end of the heat exchanger and then flows out from an outlet end of the heat exchanger after being converted into a freezing working medium in the heat exchanger, and the outlet end of the heat exchanger is in communication with the output connector. The cryoablation system further comprises a check valve; an inlet end of the check valve is in communication with the output connector, and an outlet end of the check valve is in communication with the inlet end of the heat exchanger. When the pressure surges, the check valve opens, so that part of the freezing tubing is in communication with part of the rewarming tubing to form a gas-venting circuit, thereby relieving the pressure surge caused by the phase change of the freezing working medium within the tubings.

The present application provides a working fluid pre-cooling system for cryoablation, comprising a first pressure vessel, a second pressure vessel, a first pipeline, and a second pipeline. The first pressure vessel is used to store liquid-phase cryogenic working fluid; the second pressure vessel is used to store gaseous working fluid; the second pipeline is connected between the first pressure vessel and the second pressure vessel; the first pipeline is connected between the first pressure vessel and the cryoablation device to transport the liquid-phase cryogenic working fluid to the cryoablation device during the ablation process. The first pipeline has an inner and outer double-layer structure. During pre-cooling, the liquid-phase cryogenic working fluid flows from the first pressure vessel through the inner layer of the first pipeline, the outer layer of the first pipeline, the second pipeline, and finally to the second pressure vessel. This system can effectively reduce the vaporization of the working fluid caused by temperature differences and eliminate air blockage. The working fluid in the outer layer acts as an isolation layer to limit heat exchange between the working fluid in the inner layer and the air, thereby extending the cryoablation time. Corresponding pipelines for recovering the working fluid are also provided, which is environmentally friendly and economical.

The application provides a disposable cryoablation catheter, which comprises an internal hollow tube body, a freezing system and a freezing unit, the freezing unit comprises a plurality of split freezing groups which are independently connected with the freezing system, and each split freezing group comprises a split fiber tube, the split fiber tube comprises a treatment section, a connecting section and a straight tube section which are sequentially arranged from a distal end to a proximal end, and the connecting section is a bendable section; an end of the tube body close to the freezing system is externally provided with a handle, and a driving distal end of the handle is connected with the connecting section, the device drives the distal treatment section to be distributed in an outward expansion mode and freely adjusted through axial and circumferential driving of the handle, the bending movement of the distal treatment section is realized in a manually controllable state, the adaptability of the cryoablation catheter to a tumor surface is improved, meanwhile, overflow of the cold source to the parts which do not need to be treated in the action range can be avoided, and the device has better safety protection significance.

A method for providing thermal conductivity data relating to an anatomical structure, comprises: receiving first spectral computed tomography data relating to the anatomical structure; calculating a fat map of the anatomical structure and a water map of the anatomical structure based on the first spectral computed tomography data; calculating the thermal conductivity data relating to the anatomical structure based on the fat map and the water map; and providing the thermal conductivity data.

A method for treatment of volume of interest (VOI), for example tumor, comprising a device for application of therapy in multi sites in a pre-defined volumetric array through a single needle insertion into the body. Therapies applied by this method include injection of therapeutic agents, including cytotoxic, immunologic and biologic drugs or drug combinations; radioactive substances; thermal ablation including radiofrequency ablation, microwave ablation, or cryoablation. The method addresses the problem of inadequate distribution of therapy throughout the VOI through a single needle insertion.

1. The name of the design product: low-temperature surgical system host (RY-300). 2. The use of the design product: for controlling refrigerant and heat medium, real-time display of refrigeration temperature, monitoring the pressure of refrigerant and heat medium, controlling disposable sterile cryoablation needle, realizing the effect of freezing and heating, and then ablating the target tissue. 3. The design points of the design product: in the external shape of the product. 4. The picture or photo that best indicates the design points: perspective view.

The application belongs to the technical field of medical devices, and particularly relates to a kind of cryoablation catheter and ablation system, the cryoablation catheter includes inner catheter and outer catheter, the outer catheter is coaxially sleeved on the outside of inner catheter, the inner catheter is configured as a multi-lumen structure, further comprising: a plurality of sealing components, a plurality of the sealing components are arranged on the outside of inner catheter;Wherein, in the initial state, a plurality of the sealing components and inner catheter are located in the inside of outer catheter, in the working state, a plurality of the sealing components and intestinal wall form an ablation closed space together. The application guides the cryoablation catheter to the target position through the guide wire, forms the ablation closed space through the cooperation of sealing components and lumen wall, inputs the cryogenic medium into the ablation closed space to freeze and ablate the lumen wall, provides a usable treatment plan for type 2 diabetes, obesity or other lumen lesion patients, and has the advantages of small trauma, less pain for patients, low surgical risk, etc.

The invention discloses a laser freezing denudation device and method for a non-solid sample, and relates to the technical field of laser denudation-inductively coupled plasma mass spectrometry detection, the laser freezing denudation device comprises a sample cell main body, a heat dissipation end, a temperature sensing line, a liquid inlet liquid nitrogen pipeline, a silver objective table, a sample moving device and a multifunctional sample groove; wherein the heat dissipation end, the temperature sensing line and the liquid nitrogen inlet pipeline are sequentially arranged outside the sample cell main body side by side; the silver objective table and the multifunctional sample tank are arranged in the sample cell main body; a rotatable part of the sample moving device is arranged outside the sample cell main body; and the silver objective table is connected with the heat dissipation end, the temperature sensing line and the liquid nitrogen inlet pipeline. The device can effectively control the sample temperature, improve the data quality of fluid inclusion and biological sample test, provide an efficient and direct detection means without pretreatment for formation water and trace solution element-isotope analysis, and has the advantages of low instrument equipment and experiment cost, and strong economical efficiency and operability.

A cryoprobe assembly includes a needle, a flexible conduit, and a handle portion configured to couple the needle to the flexible conduit to create a cryogen flow path. The flexible conduit includes a counterflow heat exchanger to transfer thermal energy from supply cryogen to return cryogen prior to reaching the needle in order to achieve a predetermined temperature during Joule-Thompson expansion in the needle.