282 results about "Cryoablation" patented technology

Embodiments herein relate to a cryoablation probe including a pre-cooler fluid circuit; a working fluid circuit; a vacuum circuit; and a shaft. The shaft includes a supply tube and a return tube surrounding the supply tube. The return tube includes a first polymer layer, wherein the first polymer layer is configured to contain fluid from the working fluid circuit; a reinforcement layer, and a second polymer layer. Other embodiments are also included herein.

In an embodiment, a cryoablation probe includes a shaft, where the shaft has a supply tube, a return tube surrounding the supply tube, an insulated portion, wherein a vacuum circuit runs through the insulated portion between the return tube and an insulating shaft, and an expansion chamber extending distally to the insulated portion. The probe further includes a distal tip configured to seal a distal end of the return tube. The distal tip has a tip portion extending distally from the distal end of the return tube and a plug portion configured to be inserted inside of the return tube. The probe includes a compressive element surrounding the return tube and the plug portion of the distal tip, configured to seal the distal tip to the return tube.

In an embodiment, a method for detecting leaks in a shaft of a cryoablation system includes placing a vacuum pump in fluid communication with a return tube and a supply tube; pulling a vacuum within the supply tube and the return tube; after pulling the vacuum for a predetermined amount of time, measuring a vacuum pressure within the supply tube and the return tube; and analysis of the vacuum pressure to assist with identifying leaks in the system.

In an embodiment, a cryoablation shaft is included having a working fluid circuit; a vacuum circuit; an insulated portion, wherein the vacuum circuit runs through the insulated portion; and an expansion chamber; a supply tube having a distal outlet in the expansion chamber, wherein fluid from the working fluid circuit travels distally down the cryoablation shaft through supply tube and expands in the expansion chamber; and a guidewire lumen including a metallic tube and a polymer sleeve configured to surround at least a portion of the metallic tube.

The invention belongs to the technical field of medical instruments, and particularly relates to a cryoablation catheter and an ablation system.The cryoablation catheter comprises an inner catheter body and an outer catheter body, the outer catheter body is coaxially arranged on the outer side of the inner catheter body in a sleeving mode, and the inner catheter body is configured to be of a multi-cavity structure; the multiple plugging assemblies are arranged on the outer side of the inner catheter; wherein in the initial state, the multiple plugging assemblies and the inner catheter are located in the outer catheter, and in the working state, the multiple plugging assemblies and the inner wall of the intestinal tract jointly form an ablation closed space. The cryoablation catheter is guided to a target position through the guide wire, the closed ablation space is formed through cooperation of the plugging assembly and the inner wall of the cavity, a freezing medium is input into the closed ablation space to conduct cryoablation on the inner wall of the cavity, an available treatment scheme is provided for patients suffering from type 2 diabetes, obesity or other cavity lesions, and meanwhile the treatment effect is improved. The device has the advantages of small trauma, less pain of patients, low surgical risk and the like.

The present invention discloses a cryoablation needle with an adjustable J-T slot position, including: a vacuum wall, a J-T slot and a J-T slot adjusting apparatus, wherein the vacuum wall includes: a needle rod and an inner tube; the needle rod is provided with a needle tip at a far end; the inner tube penetrates through the needle rod, and an interlayer is formed between the inner tube and the needle rod; the J-T slot penetrates through the inner tube; a far end of the J-T slot is capable of being switched between at least two adjusting positions relative to the vacuum wall, the two adjusting positions including: a first adjusting position and a second adjusting position; the first adjusting position is located in a target area; and the second adjusting position is located in a vacuum insulation area.

The utility model provides a flexible cryoablation catheter. The flexible cryoablation catheter comprises a needle; the far end of the flexible pipeline is connected with the needle head, the flexible pipeline sequentially wraps a vacuum forming layer, a first air return pipeline and a first air inlet pipeline from outside to inside in the radial direction, the first air inlet pipeline is used for introducing a freezing medium, a gap is formed between the far end of the first air inlet pipeline and the needle head, and the first air return pipeline is communicated with the first air inlet pipeline. A freezing medium is led out from the first air inlet pipeline through the gap and is recycled through the first air return pipeline; and the vacuum forming layer is connected with a vacuumizing device, so that when the vacuumizing device works, the vacuum forming layer forms vacuum. According to the flexible cryoablation catheter, the technical problem that a metal hard rod of a probe cannot be bent to enter along with a natural orifice and can only enter through puncture of a needle head is solved. And the conditions of injury, bleeding and the like caused by puncture of the skin are avoided.

The invention relates to the technical field of medical instruments, in particular to a cryoablation needle based on radio frequency rewarming, the medical instrument comprises a needle body, a capillary catheter, a first air inlet pipe, a second air inlet pipe, a needle tube, an insulating tube, a vacuum tube and a radio frequency welding wire, and after the needle body on the needle tube is led into tissue by an operator, the needle body is heated to be cooled; the tissue is frozen after air is injected through the first air inlet pipe and the second air inlet pipe to be cooled, then the tissue is rapidly heated under the action of the radio frequency welding line on the needle tube and is inactivated after multiple times of circulation, treatment is completed, meanwhile, internal redundant tissue fluid is automatically and rapidly guided out through the capillary catheter, secondary infection is avoided, and the device is simple in structure and convenient to operate. The problem of treatment of diseased tissues is effectively solved, and the device has good practicability and economical efficiency and is beneficial to popularization and use of equipment.

The invention relates to a cryoablation catheter with a supporting device, which comprises a sheath tube, an air inlet tube, an air return tube, a guide wire cavity tube, a bag body, the supporting device and a handle, the far end of the sheath tube is fixedly connected with the near end of the bag body, the near end of the sheath tube is fixedly connected with the handle, the far end of the bag body is fixedly connected with the far end of the guide wire cavity tube, and the bag body is fixedly connected with the handle. The supporting device is composed of an inner supporting piece and an outer supporting piece, the inner supporting piece is arranged in the bag body, the outer supporting piece is arranged outside the bag body, the supporting device is of a self-expanding structure, when the supporting device is converted from a compressed state to an expanded state, the inner supporting piece supports the inner wall of the bag body, and the outer supporting piece supports the outer wall of the bag body. The capsule body is tightly attached to a target area, the outer supporting piece is supported on the inner wall of a blood vessel, and a blood flow channel is established between the outer side of the capsule body and the inner wall of the blood vessel.

The invention relates to a cryoablation system, a cryoablation catheter and a control method of the cryoablation catheter. The cryoablation catheter comprises a slender body, an expandable assembly and a temperature measuring assembly, the expandable assembly is arranged at the far end of the slender body, and the expandable assembly can block a vein mouth when in an expanded structure; the slender body comprises an outer tube and a main body tube, the outer tube and the main body tube define an airflow channel, the main body tube is provided with a first conveying channel, the airflow channel is communicated with the expandable assembly, and the first conveying channel penetrates through the main body tube and is used for conveying mild liquid to veins; the temperature measuring assembly is arranged on the expandable assembly and can detect the temperature of the vein mouth so as to judge the effectiveness of plugging of the expandable assembly. Thus, the temperature measuring assembly on the expandable assembly is used for measuring temperature changes to judge the blocking state, the usage amount of contrast agents and X-rays can be reduced, the specific leakage position can be judged, ablation treatment can be conveniently carried out in the later period, and the treatment effect is guaranteed.

A cryoprobe includes a needle defining an internal cavity, a cryogen conduit positioned in the internal cavity, an adjustable insulating sleeve positioned in the inner cavity radially outward of the cryogen conduit, and a heater configured to heat the needle to predetermined temperature.

Disclosed are a freezing and electric ablation combined ablation system, an ablation needle, and a control method. The ablation system (100) comprises: a control module (150), and a freezing module (112) and an electric ablation module (121) connected thereto. The freezing module (112) and the electric ablation module (121) are connected to the ablation needle. The freezing module (112) freezes the target tissue to below 0 °C by means of a cryoablation needle, and performs cryoablation and / or freezing fixation and / or freezing anesthesia on the target tissue (240); the electric ablation module (121) is at least connected to two electrodes (11) insulated from each other, the at least one electrode part is located in a shallow freezing area (210) or can be converted into a deep freezing area (220) of the shallow freezing area, and the electric ablation module (121) performs electric ablation on the target tissue (240) by means of the electrodes (11). The freezing and electric ablation synergistically act on the same target tissue (240). By selectively controlling the temperature of the freezing area, effective electric ablation is carried out on the outer edge range of the freezing area.

The invention discloses an adjustable targeting area type cryoablation needle with a heating function and a novel refrigerant hole structure, and belongs to the technical field of interventional medical instruments, the adjustable targeting area type cryoablation needle comprises a needle rod, a vacuum wall, a J-T groove, a J-T groove sleeve and an adjusting device; the vacuum wall is sleeved with the needle rod, the area from the far end of the needle rod to the far end of the vacuum wall is a target area, the area of the vacuum wall is a vacuum heat insulation area, and the vacuum wall comprises a vacuum wall outer pipe and a vacuum wall inner pipe; the J-T groove is formed in the vacuum wall inner tube, the far end of the J-T groove is located in the far end of the needle rod, and a side hole is formed in the side wall of the J-T groove; the J-T groove is sleeved with the J-T groove sleeve; the J-T groove sleeve and the vacuum wall are fixed together through a connecting piece and can move synchronously and axially. And the adjusting device is used for adjusting the length of the target area. By innovatively designing the arrangement of the cooling ablation air holes and the heat conduction isolation layer, more accurate control over the cryoablation range is achieved, and the safety and effectiveness of cryoablation interventional therapy are improved.

The embodiment of the utility model discloses a cryoablation catheter and a cryoablation system. The cryoablation catheter comprises a transmission assembly, an intervention assembly and an ablation assembly which are sequentially connected and communicated, the transmission assembly conveys a variable-temperature working medium into the ablation assembly through the intervention assembly for ablation operation, and the variable-temperature working medium flows back from the intervention assembly and the transmission assembly in sequence after being subjected to heat exchange through the ablation assembly and is output; the transmission assembly comprises a transmission liquid inlet pipe which is connected and communicated with the intervention assembly; the transmission pressure relief pipe is arranged outside the transmission liquid inlet pipe in a sleeving mode to form a pressure relief channel, a pressure relief hole is formed in the transmission liquid inlet pipe, and the pressure relief hole communicates with the transmission pressure relief pipe; the transmission air return pipe is connected and communicated with the intervention assembly, and the transmission pressure relief pipe is sleeved with the transmission air return pipe to form an air return channel. According to the cryoablation catheter, the pressure relief hole is formed, so that the freezing medium can be continuously, rapidly and stably conveyed into the ablation assembly from the intervention assembly to be pre-cooled, the pre-cooling temperature is rapidly reached, the pre-cooling efficiency is effectively improved, the pressure relief hole is formed in the conveying liquid inlet pipe, and the machining difficulty and the machining cost are reduced.

The embodiment of the utility model relates to the technical field of cryotherapy, in particular to a cryoablation system which comprises a freezing module, a rewarming module and an ablation module. The freezing module and the rewarming module are respectively connected and communicated with the ablation module, the freezing module conveys a cold working medium into the ablation module for cooling ablation consumables in the ablation module, and the rewarming module conveys a hot working medium into the ablation module for heating the ablation consumables in the ablation module. The liquid nitrogen conveying device has the advantages that heat exchange between liquid nitrogen and air is achieved through the heat transfer pipe, so that nitrogen is generated and used for providing pressure for conveying the liquid nitrogen, arrangement of an electrical structure for heating or pressurizing is reduced, equipment cost is reduced, meanwhile, use of electrical components is reduced, stability of equipment is improved, and the possibility of faults is reduced.

A probe for performing a cryoablation treatment that includes a handle with a heater configured to heat a fluid and a needle connected to the handle and extending therefrom to a distal end. The needle includes a pathway configured to move the fluid from the handle toward the distal end to heat the needle.

A system and method are presented for treating targeted tissue using cryoablation. A linear endobronchial ultrasound (EBUS) device is positioned adjacent the targeted tissue and is used to guide a percutaneously inserted cryoprobe into the targeted tissue. The EBUS device is partially rotated in order to create multiple image slices that are combined together. To overcome the acoustic shadow created by the ice ball, a 3D model is created of the ice ball based on the locations identified on visible portion of the ice ball's peripheral surface. These locations are mirrored across an axis defined for the cryoprobe to define an approximate location for the hidden, non-visible periphery. This model is then displayed along with the location of the targeted tissue and an indication of the killing zone of the ice ball defined by a selected isotherm.

A method of positioning a cryoprobe includes receiving a cryoprobe repositioning selector indicating a desire to reposition a cryoprobe relative to a target tissue; obtaining cryoprobe operating information from one or more sensors positioned in the cryoprobe, wherein the cryoprobe operating information characterizes one or more operating parameters of the cryoprobe; energizing a heater in the cryoprobe to heat a tip of the cryoprobe to a predetermined cautery temperature threshold; and displaying a cautery indicator when the tip of the cryoprobe is greater than or equal to the cautery temperature threshold.

Methods and systems for cryoablation cooling are disclosed. According to one aspect, a cryoablation cooling system includes cooling equipment having at least one operating parameter. The cryoablation cooling system also includes at least one external environment sensor, each of the at least one external environment sensors being configured to measure an environmental parameter external to the cooling equipment. At least one equipment sensor is included to measure an operating parameter of the cooling equipment. The cryoablation cooling system further includes a sub-cooler control system configured to determine an adjustment to at least one operating parameter of the cooling equipment to obtain a target cooling power based at least in part on the at least one measured external environmental parameter and the at least one measured operating parameter.

The utility model relates to a balloon catheter and a cryoablation system. The balloon catheter comprises an outer tube, an inner tube, a balloon, a pull wire and a handle. The inner tube is sleeved with the outer tube, and the far end of the outer tube is fixedly connected with the near end of the balloon. The far end part of the inner tube is exposed out of the outer tube, and the far end of the inner tube is fixedly connected with the far end of the balloon; an air inlet cavity and an air return cavity which are respectively communicated with fluid of the balloon are arranged between the inner tube and the outer tube; the far end of the pull wire is fixed to the far end of the balloon, the near end of the pull wire extends out of the body, and the pull wire is used for controlling bending deformation of the balloon; the handle is connected to the near end of the outer tube and provided with an air inlet connector and an air return connector which are communicated with the air inlet cavity and the air return cavity respectively. The bending degree of the balloon can be adjusted through the pull wire, the balloon can be suitable for being attached to blood vessel walls of various shapes, and blood flow cannot be blocked.

The present application relates to a cryoablation system, a cryoablation catheter (10) and a control method therefor. The cryoablation catheter (10) comprises an elongated body (100), an expandable assembly (200) and a temperature measuring assembly (300). The expandable assembly (200) is arranged at the distal end of the elongated body (100); and when the expandable assembly (200) is in an expanded configuration, the expandable assembly can block a venous orifice portion (510). The elongated body (100) comprises an outer tube (110) and a main body tube (120), the outer tube (110) and the main body tube (120) enclosing an airflow channel (130); the main body tube (120) is provided with a first delivery channel; the airflow channel (130) is in communication with the expandable assembly (200); and the first delivery channel penetrates through the main body tube (120) and is used for delivering a mild liquid to a vein (50). The temperature measuring assembly (300) is provided on the expandable assembly (200) and can measure the temperature of the venous orifice portion (510), so as to determine the effectiveness of the blocking achieved by the expandable assembly (200).

The invention discloses an ablation system and method for a cardiovascular balloon. The system comprises a multi-section temperature control balloon, a cooling rate control module, a flow control module, a pressure adjusting module, an intelligent feedback control module and a safety protection module. The method comprises the following steps: initializing a multi-section temperature control balloon, and deploying a cooling rate control module, a flow control module, a pressure regulation module, an intelligent feedback control module and a safety protection module; the initial temperature Ti, 0 of each section is obtained, the low temperature related to the treatment target is set as the target temperature Ti, target, and the refrigerant flow Fi, 0 and the initial pressure Pi, 0 of each section are initialized; in the real-time control stage of the freezing process, impedance change of cardiovascular tissue is monitored in real time to judge the freezing effect, and various control parameters in the cryoablation process are predicted and adjusted according to constantly changing real-time data; and monitoring whether abnormal temperature change or abnormal pressure change exists between the freezing balloon and the cardiovascular tissue, and if the abnormal temperature change or abnormal pressure change occurs, performing emergency treatment.

The invention discloses a cryoablation needle, and relates to the field of medical equipment, the cryoablation needle comprises a handle, a needle rod, a first air inlet pipe assembly, an air return pipe, a connecting sleeve, a sealing head, a clamping sleeve type compression joint and a second air inlet pipe assembly, the interior of the needle rod is arranged to be of a cavity structure with one end open, and one end of the connecting sleeve is fixedly connected with the handle; the sealing head is arranged on the needle rod in a sleeving mode and is in threaded sealing connection with the inserting end of the connecting sleeve, the air inlet end of the air return pipe is arranged in an air return channel of the connecting sleeve, and the cavity of the needle rod, the air return channel of the connecting sleeve and the air return pipe jointly form an air return channel. The air outlet end of the second air inlet pipe assembly is fixedly connected to the open end of the air return channel of the connecting sleeve and used for being in butt joint with the air inlet end of the first air inlet pipe assembly, and the clamping sleeve type compression connector is fixedly connected to the end of the telescopic structure of the connecting sleeve. The length of the needle rod exposed out of the body of a patient can be adjusted according to actual needs, and meanwhile the connection sealing performance of the needle rod is improved.

Embodiments herein relate to cryoablation systems. In an embodiment, a cryosurgery system includes a closed-loop working fluid circuit configured to contain a working fluid. The system can include a compressor configured to increase the pressure of the working fluid. The system can include a heat exchanger configured to lower the temperature of the working fluid. The system can include a cryoablation probe having a shaft having a supply tube and a return tube surrounding the supply tube. The system is configured so that, after exiting the first heat exchanger, the working fluid will enter the cryoablation probe, travel to the expansion chamber, expand in the expansion chamber at a Joule-Thomson orifice, travel to the cryoablation probe interface via the return tube, exit the cryoablation probe via the working fluid outlet, enter the compressor, and enter the first heat exchanger.

The invention discloses a cryoablation catheter system for pulmonary artery stent internal restenosis, and belongs to the field of medical instruments, the cryoablation catheter system comprises a catheter main body arranged on a guide wire, the catheter main body is provided with a treatment assembly, the treatment assembly is located at the far end of the catheter main body, the catheter main body is provided with a control handle, and the control handle is located at the far end of the catheter main body. The control handle is located at the near end of the catheter body, and the treatment assembly comprises a near-end balloon, a far-end balloon and a freezing balloon. When the near-end balloon and the far-end balloon are simultaneously full, a closed treatment cabin isolated from near-end blood flow and far-end blood flow can be formed in a blood vessel of a target treatment section, the freezing balloon is located in the treatment cabin, the closed treatment cabin thoroughly eliminates the blood flow hot pool effect, cold is prevented from being taken away by the blood flow, and the treatment effect is improved. Freezing energy is intensively acted on a diseased region, so that the ablation efficiency and accuracy are improved; meanwhile, thrombus, tissue debris and whole body blood flow which fall off in the treatment process are isolated, the risk of far-end embolism is reduced from the source, and damage to the blood vessel wall is avoided.

1. The name of the product of this design: cryoablation equipment. 2. Purpose of the product with this appearance design: used in conjunction with a cryoablation catheter for cryoablation treatment of lesions. 3. The design key point of this appearance design product lies in the combination of shape and pattern. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

The present invention provides an integrated pulse and cryoablation machine, including a pulse and cryoablation generator, a connecting cable, a refrigerant medium transmission tube, a catheter, and a balloon; the pulse and cryoablation generator has two functions of pulse and cryoablation, and pulse and cryoablation can be selected on its interface; the connecting cable connects the pulse and cryoablation generator to the catheter to transmit pulse energy, and the refrigerant medium transmission tube delivers the refrigerant generated by the pulse and cryoablation generator to the balloon; the balloon surrounds the catheter, the end of the catheter extends from the far end of the balloon and folds back to surround the outer surface of the balloon, and a plurality of groups of electrodes are provided on the catheter for use as pulse electrodes and extracting electrocardiographic signals; when pulse ablation is selected, discharge occurs between the electrodes to achieve pulse ablation; when cryoablation is selected, the refrigerant is transmitted to the far end of the balloon to produce a freezing effect, and the electrodes extract electrocardiographic signals. The present invention realizes the selective use of pulse and cryoablation and is safer.

The embodiments of the present invention relate to the field of cryoablation and disclose a cryoablation temperature prediction method, device, electronic device and storage medium, including: constructing a vascular network diagram based on the vascular centerline in the three-dimensional imaging data before the cryoablation operation, the nodes in the vascular network diagram represent the vascular bifurcation points, and the blood edges represent the vascular connection relationship; during the cryoablation process, using a pre-trained temperature prediction model to predict the temperature field of the target sampling point, the temperature prediction model includes a physical information neural network and a graph neural network; the physical information neural network uses the biological heat conduction equation as a constraint condition to predict the temperature field of the target sampling point, and the graph neural network is used to predict the blood perfusion coefficient of each node in the vascular network diagram to determine the blood perfusion coefficient contained in the biological heat conduction equation, which solves the problem of real-time prediction of cryoablation temperature in accordance with physical laws, so that the results conform to physical laws and meet the real-time requirements during the operation.

Embodiments herein relate to cryoablation systems. In an embodiment, a cryosurgery system includes a closed-loop working fluid circuit configured to contain a working fluid. The system can include a compressor configured to increase the pressure of the working fluid. The system can include a heat exchanger configured to lower the temperature of the working fluid. The system can include a cryoablation probe having a shaft having a supply tube and a return tube surrounding the supply tube. The system is configured so that, after exiting the first heat exchanger, the working fluid will enter the cryoablation probe, travel to the expansion chamber, expand in the expansion chamber at a Joule-Thomson orifice, travel to the cryoablation probe interface via the return tube, exit the cryoablation probe via the working fluid outlet, enter the compressor, and enter the first heat exchanger.

The application relates to the technical field of medical devices, in particular to a lung tumor treatment device based on irreversible electroporation and cryoablation, which comprises a single needle for generating high-voltage electric pulses, an ice knife for conveying cold gas medium and a CT display module for displaying CT images in real time, comprises a puncture sleeve, the puncture sleeve is provided with a sliding groove, the single needle and the ice knife are in gap cooperation with the sliding groove; a needle head is detachably connected in the sliding groove, the puncture sleeve is communicated with a conveying pipe, and the puncture sleeve is provided with an outlet for discharging the cold gas medium at one end; the sliding groove is also communicated with a collection mechanism for collecting external tissues, and the collection mechanism is used for collecting the external tissues based on the pushing of the needle head, the single needle and the ice knife; the application is convenient for switching surgical tools, reduces the damage to the surrounding tissues in the body during the treatment of lung ground glass nodules, and guarantees the removal effect of the lung ground glass nodules.