162 results about "Cryoablation" patented technology

In an embodiment, a cryoablation probe includes a shaft, where the shaft has a supply tube, a return tube surrounding the supply tube, an insulated portion, wherein a vacuum circuit runs through the insulated portion between the return tube and an insulating shaft, and an expansion chamber extending distally to the insulated portion. The probe further includes a distal tip configured to seal a distal end of the return tube. The distal tip has a tip portion extending distally from the distal end of the return tube and a plug portion configured to be inserted inside of the return tube. The probe includes a compressive element surrounding the return tube and the plug portion of the distal tip, configured to seal the distal tip to the return tube.

A cryoprobe includes a needle defining an internal cavity, a cryogen conduit positioned in the internal cavity, an adjustable insulating sleeve positioned in the inner cavity radially outward of the cryogen conduit, and a heater configured to heat the needle to predetermined temperature.

The invention discloses an adjustable targeting area type cryoablation needle with a heating function and a novel refrigerant hole structure, and belongs to the technical field of interventional medical instruments, the adjustable targeting area type cryoablation needle comprises a needle rod, a vacuum wall, a J-T groove, a J-T groove sleeve and an adjusting device; the vacuum wall is sleeved with the needle rod, the area from the far end of the needle rod to the far end of the vacuum wall is a target area, the area of the vacuum wall is a vacuum heat insulation area, and the vacuum wall comprises a vacuum wall outer pipe and a vacuum wall inner pipe; the J-T groove is formed in the vacuum wall inner tube, the far end of the J-T groove is located in the far end of the needle rod, and a side hole is formed in the side wall of the J-T groove; the J-T groove is sleeved with the J-T groove sleeve; the J-T groove sleeve and the vacuum wall are fixed together through a connecting piece and can move synchronously and axially. And the adjusting device is used for adjusting the length of the target area. By innovatively designing the arrangement of the cooling ablation air holes and the heat conduction isolation layer, more accurate control over the cryoablation range is achieved, and the safety and effectiveness of cryoablation interventional therapy are improved.

A probe for performing a cryoablation treatment that includes a handle with a heater configured to heat a fluid and a needle connected to the handle and extending therefrom to a distal end. The needle includes a pathway configured to move the fluid from the handle toward the distal end to heat the needle.

A method of positioning a cryoprobe includes receiving a cryoprobe repositioning selector indicating a desire to reposition a cryoprobe relative to a target tissue; obtaining cryoprobe operating information from one or more sensors positioned in the cryoprobe, wherein the cryoprobe operating information characterizes one or more operating parameters of the cryoprobe; energizing a heater in the cryoprobe to heat a tip of the cryoprobe to a predetermined cautery temperature threshold; and displaying a cautery indicator when the tip of the cryoprobe is greater than or equal to the cautery temperature threshold.

The invention discloses a cryoablation needle, and relates to the field of medical equipment, the cryoablation needle comprises a handle, a needle rod, a first air inlet pipe assembly, an air return pipe, a connecting sleeve, a sealing head, a clamping sleeve type compression joint and a second air inlet pipe assembly, the interior of the needle rod is arranged to be of a cavity structure with one end open, and one end of the connecting sleeve is fixedly connected with the handle; the sealing head is arranged on the needle rod in a sleeving mode and is in threaded sealing connection with the inserting end of the connecting sleeve, the air inlet end of the air return pipe is arranged in an air return channel of the connecting sleeve, and the cavity of the needle rod, the air return channel of the connecting sleeve and the air return pipe jointly form an air return channel. The air outlet end of the second air inlet pipe assembly is fixedly connected to the open end of the air return channel of the connecting sleeve and used for being in butt joint with the air inlet end of the first air inlet pipe assembly, and the clamping sleeve type compression connector is fixedly connected to the end of the telescopic structure of the connecting sleeve. The length of the needle rod exposed out of the body of a patient can be adjusted according to actual needs, and meanwhile the connection sealing performance of the needle rod is improved.

Embodiments herein relate to cryoablation systems. In an embodiment, a cryosurgery system includes a closed-loop working fluid circuit configured to contain a working fluid. The system can include a compressor configured to increase the pressure of the working fluid. The system can include a heat exchanger configured to lower the temperature of the working fluid. The system can include a cryoablation probe having a shaft having a supply tube and a return tube surrounding the supply tube. The system is configured so that, after exiting the first heat exchanger, the working fluid will enter the cryoablation probe, travel to the expansion chamber, expand in the expansion chamber at a Joule-Thomson orifice, travel to the cryoablation probe interface via the return tube, exit the cryoablation probe via the working fluid outlet, enter the compressor, and enter the first heat exchanger.

The invention discloses a cryoablation catheter system for pulmonary artery stent internal restenosis, and belongs to the field of medical instruments, the cryoablation catheter system comprises a catheter main body arranged on a guide wire, the catheter main body is provided with a treatment assembly, the treatment assembly is located at the far end of the catheter main body, the catheter main body is provided with a control handle, and the control handle is located at the far end of the catheter main body. The control handle is located at the near end of the catheter body, and the treatment assembly comprises a near-end balloon, a far-end balloon and a freezing balloon. When the near-end balloon and the far-end balloon are simultaneously full, a closed treatment cabin isolated from near-end blood flow and far-end blood flow can be formed in a blood vessel of a target treatment section, the freezing balloon is located in the treatment cabin, the closed treatment cabin thoroughly eliminates the blood flow hot pool effect, cold is prevented from being taken away by the blood flow, and the treatment effect is improved. Freezing energy is intensively acted on a diseased region, so that the ablation efficiency and accuracy are improved; meanwhile, thrombus, tissue debris and whole body blood flow which fall off in the treatment process are isolated, the risk of far-end embolism is reduced from the source, and damage to the blood vessel wall is avoided.

The embodiments of the present invention relate to the field of cryoablation and disclose a cryoablation temperature prediction method, device, electronic device and storage medium, including: constructing a vascular network diagram based on the vascular centerline in the three-dimensional imaging data before the cryoablation operation, the nodes in the vascular network diagram represent the vascular bifurcation points, and the blood edges represent the vascular connection relationship; during the cryoablation process, using a pre-trained temperature prediction model to predict the temperature field of the target sampling point, the temperature prediction model includes a physical information neural network and a graph neural network; the physical information neural network uses the biological heat conduction equation as a constraint condition to predict the temperature field of the target sampling point, and the graph neural network is used to predict the blood perfusion coefficient of each node in the vascular network diagram to determine the blood perfusion coefficient contained in the biological heat conduction equation, which solves the problem of real-time prediction of cryoablation temperature in accordance with physical laws, so that the results conform to physical laws and meet the real-time requirements during the operation.

Embodiments herein relate to cryoablation systems. In an embodiment, a cryosurgery system includes a closed-loop working fluid circuit configured to contain a working fluid. The system can include a compressor configured to increase the pressure of the working fluid. The system can include a heat exchanger configured to lower the temperature of the working fluid. The system can include a cryoablation probe having a shaft having a supply tube and a return tube surrounding the supply tube. The system is configured so that, after exiting the first heat exchanger, the working fluid will enter the cryoablation probe, travel to the expansion chamber, expand in the expansion chamber at a Joule-Thomson orifice, travel to the cryoablation probe interface via the return tube, exit the cryoablation probe via the working fluid outlet, enter the compressor, and enter the first heat exchanger.

The application relates to the technical field of medical devices, in particular to a lung tumor treatment device based on irreversible electroporation and cryoablation, which comprises a single needle for generating high-voltage electric pulses, an ice knife for conveying cold gas medium and a CT display module for displaying CT images in real time, comprises a puncture sleeve, the puncture sleeve is provided with a sliding groove, the single needle and the ice knife are in gap cooperation with the sliding groove; a needle head is detachably connected in the sliding groove, the puncture sleeve is communicated with a conveying pipe, and the puncture sleeve is provided with an outlet for discharging the cold gas medium at one end; the sliding groove is also communicated with a collection mechanism for collecting external tissues, and the collection mechanism is used for collecting the external tissues based on the pushing of the needle head, the single needle and the ice knife; the application is convenient for switching surgical tools, reduces the damage to the surrounding tissues in the body during the treatment of lung ground glass nodules, and guarantees the removal effect of the lung ground glass nodules.

Provided in the present invention is a cryoablation system, which comprises a gas source, a rewarming tubing, a freezing tubing, and an output connector. The rewarming tubing is connected in parallel to the freezing tubing, the freezing tubing comprises a heat exchanger, a working medium flows in from an inlet end of the heat exchanger and then flows out from an outlet end of the heat exchanger after being converted into a freezing working medium in the heat exchanger, and the outlet end of the heat exchanger is in communication with the output connector. The cryoablation system further comprises a check valve; an inlet end of the check valve is in communication with the output connector, and an outlet end of the check valve is in communication with the inlet end of the heat exchanger. When the pressure surges, the check valve opens, so that part of the freezing tubing is in communication with part of the rewarming tubing to form a gas-venting circuit, thereby relieving the pressure surge caused by the phase change of the freezing working medium within the tubings.

The present application provides a working fluid pre-cooling system for cryoablation, comprising a first pressure vessel, a second pressure vessel, a first pipeline, and a second pipeline. The first pressure vessel is used to store liquid-phase cryogenic working fluid; the second pressure vessel is used to store gaseous working fluid; the second pipeline is connected between the first pressure vessel and the second pressure vessel; the first pipeline is connected between the first pressure vessel and the cryoablation device to transport the liquid-phase cryogenic working fluid to the cryoablation device during the ablation process. The first pipeline has an inner and outer double-layer structure. During pre-cooling, the liquid-phase cryogenic working fluid flows from the first pressure vessel through the inner layer of the first pipeline, the outer layer of the first pipeline, the second pipeline, and finally to the second pressure vessel. This system can effectively reduce the vaporization of the working fluid caused by temperature differences and eliminate air blockage. The working fluid in the outer layer acts as an isolation layer to limit heat exchange between the working fluid in the inner layer and the air, thereby extending the cryoablation time. Corresponding pipelines for recovering the working fluid are also provided, which is environmentally friendly and economical.

The application provides a disposable cryoablation catheter, which comprises an internal hollow tube body, a freezing system and a freezing unit, the freezing unit comprises a plurality of split freezing groups which are independently connected with the freezing system, and each split freezing group comprises a split fiber tube, the split fiber tube comprises a treatment section, a connecting section and a straight tube section which are sequentially arranged from a distal end to a proximal end, and the connecting section is a bendable section; an end of the tube body close to the freezing system is externally provided with a handle, and a driving distal end of the handle is connected with the connecting section, the device drives the distal treatment section to be distributed in an outward expansion mode and freely adjusted through axial and circumferential driving of the handle, the bending movement of the distal treatment section is realized in a manually controllable state, the adaptability of the cryoablation catheter to a tumor surface is improved, meanwhile, overflow of the cold source to the parts which do not need to be treated in the action range can be avoided, and the device has better safety protection significance.

A method for providing thermal conductivity data relating to an anatomical structure, comprises: receiving first spectral computed tomography data relating to the anatomical structure; calculating a fat map of the anatomical structure and a water map of the anatomical structure based on the first spectral computed tomography data; calculating the thermal conductivity data relating to the anatomical structure based on the fat map and the water map; and providing the thermal conductivity data.

A method for treatment of volume of interest (VOI), for example tumor, comprising a device for application of therapy in multi sites in a pre-defined volumetric array through a single needle insertion into the body. Therapies applied by this method include injection of therapeutic agents, including cytotoxic, immunologic and biologic drugs or drug combinations; radioactive substances; thermal ablation including radiofrequency ablation, microwave ablation, or cryoablation. The method addresses the problem of inadequate distribution of therapy throughout the VOI through a single needle insertion.

1. The name of the design product: low-temperature surgical system host (RY-300). 2. The use of the design product: for controlling refrigerant and heat medium, real-time display of refrigeration temperature, monitoring the pressure of refrigerant and heat medium, controlling disposable sterile cryoablation needle, realizing the effect of freezing and heating, and then ablating the target tissue. 3. The design points of the design product: in the external shape of the product. 4. The picture or photo that best indicates the design points: perspective view.

The application belongs to the technical field of medical devices, and particularly relates to a kind of cryoablation catheter and ablation system, the cryoablation catheter includes inner catheter and outer catheter, the outer catheter is coaxially sleeved on the outside of inner catheter, the inner catheter is configured as a multi-lumen structure, further comprising: a plurality of sealing components, a plurality of the sealing components are arranged on the outside of inner catheter;Wherein, in the initial state, a plurality of the sealing components and inner catheter are located in the inside of outer catheter, in the working state, a plurality of the sealing components and intestinal wall form an ablation closed space together. The application guides the cryoablation catheter to the target position through the guide wire, forms the ablation closed space through the cooperation of sealing components and lumen wall, inputs the cryogenic medium into the ablation closed space to freeze and ablate the lumen wall, provides a usable treatment plan for type 2 diabetes, obesity or other lumen lesion patients, and has the advantages of small trauma, less pain for patients, low surgical risk, etc.

The invention discloses a laser freezing denudation device and method for a non-solid sample, and relates to the technical field of laser denudation-inductively coupled plasma mass spectrometry detection, the laser freezing denudation device comprises a sample cell main body, a heat dissipation end, a temperature sensing line, a liquid inlet liquid nitrogen pipeline, a silver objective table, a sample moving device and a multifunctional sample groove; wherein the heat dissipation end, the temperature sensing line and the liquid nitrogen inlet pipeline are sequentially arranged outside the sample cell main body side by side; the silver objective table and the multifunctional sample tank are arranged in the sample cell main body; a rotatable part of the sample moving device is arranged outside the sample cell main body; and the silver objective table is connected with the heat dissipation end, the temperature sensing line and the liquid nitrogen inlet pipeline. The device can effectively control the sample temperature, improve the data quality of fluid inclusion and biological sample test, provide an efficient and direct detection means without pretreatment for formation water and trace solution element-isotope analysis, and has the advantages of low instrument equipment and experiment cost, and strong economical efficiency and operability.

A cryoprobe assembly includes a needle, a flexible conduit, and a handle portion configured to couple the needle to the flexible conduit to create a cryogen flow path. The flexible conduit includes a counterflow heat exchanger to transfer thermal energy from supply cryogen to return cryogen prior to reaching the needle in order to achieve a predetermined temperature during Joule-Thompson expansion in the needle.

A cryoablation tool may include a catheter. The catheter may have a shaft having: a proximal end, a distal end, a shaft wall extending between the proximal end and the distal end, the shaft wall having an outer surface and an inner surface and a vacuum gap defined therebetween that forms a vacuum chamber, the inner surface of the shaft wall being gas permeable, a shaft lumen bounded by the inner surface of the shaft wall, the shaft lumen for carrying a cryogen gas, and the vacuum chamber having a proximal opening connectable to a vacuum source, the proximal opening establishing vacuum communication between the vacuum chamber and the vacuum source.

A system for performing cryoablation treatments includes at least one computing device that is configured to obtain cryoablation operating information from one or more sensors coupled to a cryoablation treatment apparatus and to obtain patient information from one or more patient monitoring apparatuses. The computing device also obtains ice formation information characterizing one or more characteristics of an iceball produced by the cryoablation treatment apparatus and compares the ice formation information to an ice formation plan. If the ice formation information differs from the ice formation plan, the computing device adjusts one or more operating parameters of the cryoablation treatment apparatus.

The application discloses a kind of frozen ablation catheter and its working method, comprising: frozen probe, first channel and second channel being communicated with frozen probe;Wherein, to form the shunt channel of first channel and second channel between first channel and second channel, shunt channel forms shunt inlet at first channel, and shunt channel forms shunt outlet at second channel;When refrigerant enters second channel from first channel through shunt channel, local low pressure is formed at shunt outlet.The application carries out different degrees of shunt in advance to high-speed flowing refrigerant, uses the local low pressure area formed by the entrainment phenomenon generated by high-speed fluid to determine whether the balloon of frozen probe exists breakage leakage by monitoring the pressure change in catheter.

The cryoablation system of the present application includes first, second, and third pressure vessels and a cryoablation device; a first pipeline for supplying liquid working fluid is connected between the first pressure vessel and the cryoablation device; a second pipeline and an eighth pipeline for reflux liquid working fluid during pre-cooling are connected between the second pressure vessel and the first pipeline, and a fourth pipeline for outputting pressure to the first pressure vessel is connected between the second pressure vessel and the first pressure vessel; the third pressure vessel is unidirectionally connected to the first pressure vessel and is connected to the second pressure vessel through a fifth pipeline to provide gaseous working fluid; a seventh pipeline for recovering the working fluid passing through the cryoablation device is connected between the second pressure vessel and the cryoablation device, and the seventh pipeline is connected to the second pressure vessel through the eighth pipeline after intersecting with the second pipeline; the second pressure vessel is connected to the cryoablation device through the sixth pipeline, thereby improving safety of use and reducing working fluid consumption.

Systems and methods for cryoablation. One example system includes an interior portion, an exterior portion and a treatment element. The system includes a first loop in the interior portion of the system, the first loop having a first controller, at least one valve, and a first sensor; a second loop in the interior portion of the system, the second loop having a second controller, and at least one valve, and a second sensor; a pressurized coolant supply in fluid communication with the first loop and the second loop; and a temperature sensor disposed on the exterior portion of the system, the temperature sensor being configured to monitor the temperature on the exterior portion of the system.

1. Name of the product in this design: Disposable sterile cryoablation needle. 2. Purpose of this product design: To monitor the temperature of ablation needle in real time using a disposable sterile cryoablation needle, and to achieve freezing and heating effects by using the cold and heat media transmitted by the low-temperature surgical system, thereby performing cryoablation treatment on the target tissue. 3. The key design features of this product are its external shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

Medical devices and related methods useful for cryoablation are described. The medical device may include a shaft defining a lumen and having a distal end portion that includes an inflatable balloon; and a tube movable along the lumen. The tube may be in fluid communication with the balloon and configured to supply a cryogenic fluid to a needle closing a distal end of the shaft and to the balloon. The medical device may be movable between a first configuration in which a distal end of the tube abuts a proximal end of the needle while the balloon is deflated, and a second configuration in which the distal end of the tube is proximal to the balloon, wherein supplying the cryogenic fluid through the tube inflates the balloon in the second configuration.

The present invention relates to a medical device (1) for cryotherapy, comprising a catheter (3) for cryoablation. The catheter (3) has an at least partly flexible, tubular shaft (5) for introducing the catheter (3) into a bodily vessel, the shaft (5) comprising a first lumen (23) for transporting a coolant to a distal end (11) of the shaft (5) and a second lumen (25) for removing the coolant from the distal end (11) of the shaft (5). The first lumen (23) is connected to a proximal end of the shaft (5) having a coolant source (21). The catheter (3) further comprises an expandable cooling chamber (29). This cooling chamber (29) is arranged at the distal end (11) of the shaft (5) and encloses an end portion of the distal end (11) of the shaft (5) and / or a first lumen portion of the first lumen (23) assigned to an end portion of the distal end (11) of the shaft (5). The coolant is suppliable to the cooling chamber (29) via the first lumen (23) and by means of at least one nozzle (33). The coolant is removable from the cooling channel (29) via the second lumen (25). Thermal energy is transferable via an outer wall (29b) of the expanded cooling chamber (29) such that a cryotherapy is performable at a treatment location. According to the invention, the end portion at the distal end (11) of the shaft (5) comprises a heat transfer element (27) which has an inner element (39) and an outer element (41) enclosing, in particular in the form of a hat, cap or cladding, the inner element (39), wherein the first lumen portion of the first lumen (23), which has a helical or rotationally asymmetric shape, is formed by the interaction of the inner element (39) and the outer element (41). Moreover, the at least one nozzle (33) uses the Joule-Thomson effect. At least one part of the end portion at the distal end (11) of the shaft (5) is in thermally conductive contact with the interior (29a) of the cooling chamber (29). This is done to cool the coolant guided in the first lumen (23) by the coolant supplied to the interior (29a) of the cooling chamber (29).

The application discloses a cryoablation catheter with controllable ablation range, which is capable of adjusting the effective cryoablation length of a balloon by adjusting the position of a displacement block, i.e. the displacement block is relatively movable on the length of the balloon, the balloon at the blocked position cannot be expanded (the expansion of the balloon is limited by the displacement block), the balloon at the unblocked position can be normally expanded (after being filled with refrigerant), and the effective cryoablation length (expandable part) of the balloon can be adjusted, so that the effective ablation range of the cryoablation balloon can be changed.

The utility model relates to a cryoablation catheter with a supporting device, which comprises a sheath tube, an air inlet tube, an air return tube, a guide wire cavity tube, a bag body, the supporting device and a handle, the far end of the sheath tube is fixedly connected with the near end of the bag body, the near end of the sheath tube is fixedly connected with the handle, the far end of the bag body is fixedly connected with the far end of the guide wire cavity tube, and the bag body is fixedly connected with the handle. The supporting device is composed of an inner supporting piece and an outer supporting piece, the inner supporting piece is arranged in the bag body, the outer supporting piece is arranged outside the bag body, the supporting device is of a self-expanding structure, when the supporting device is converted from a compressed state to an expanded state, the inner supporting piece supports the inner wall of the bag body, and the outer supporting piece supports the outer wall of the bag body. The capsule body is tightly attached to a target area, the outer supporting piece is supported on the inner wall of a blood vessel, and a blood flow channel is established between the outer side of the capsule body and the inner wall of the blood vessel.