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265 results about "Saline solutions" patented technology

Multi-layer multifunctional hydrogel microsphere for diabetic wounds as well as preparation method and application of multi-layer multifunctional hydrogel microsphere

The invention belongs to the technical field of biomedical materials, and particularly relates to a multi-layer multifunctional hydrogel microsphere for diabetic wounds as well as a preparation method and application of the multi-layer multifunctional hydrogel microsphere. The preparation method comprises the following steps: firstly, synthesizing a chitosan derivative with proper amino and aldehyde group contents, oxidized macromolecules and modified chitin; then preparing photocuring hydrogel microspheres by utilizing a microfluidic technology, and sequentially immersing the photocuring hydrogel microspheres into an oxidized polymer solution, a modified chitin solution, a tannic acid solution and a metal salt solution, so as to construct the hydrogel microspheres with a multifunctional layer structure. The invention further provides specific application intervals of parameters such as solvents used by various solutions, concentration ranges and soaking time. The preparation method provided by the invention has expansibility and universality, various types of microspheres can be constructed for sequential release of bioactive substances, and the requirements of tissue repair are met.
Owner:THE FIRST AFFILIATED HOSPITAL OF MEDICAL COLLEGE OF XIAN JIAOTONG UNIV

Treatment method for fermenting smelly mandarin fish by coupling gradient salt control and directional inoculation

The invention discloses a treatment method for fermenting smelly mandarin fish by coupling gradient salt control and directional inoculation, which comprises the following steps of: pretreating the smelly mandarin fish, putting the smelly mandarin fish into ozone-containing water for bacteria reduction treatment, then putting the smelly mandarin fish into a salt solution for pickling, finally inoculating bacteria liquid into the pickled smelly mandarin fish for fermentation treatment, cleaning, draining, packaging and quickly freezing after fermentation is finished, and thus obtaining the smelly mandarin fish. According to the method, the fermentation production process of the smelly mandarin fish is adjusted and standardized, the microorganism content of the slaughtered smelly mandarin fish is reduced through pretreatment, then the bacteria-reduced smelly mandarin fish is pickled with a low-concentration sodium chloride aqueous solution, meanwhile, the screened strains (psychrobacter halophilus and lactobacillus plantarum) are inoculated, and compared with traditional fermentation, the method is easy to operate, low in cost and high in yield. The product quality is stable, the defective rate is low, the labor cost is saved, the speed is high, the volatile basic nitrogen of the obtained smelly mandarin fish is less than or equal to 30mg / 100g, and the peroxide value (in terms of fat) is less than or equal to 2.5 g / 100g.
Owner:JIANGNAN UNIV

Systems and methods for drug delivery

A drug delivery system includes a packaging housing a first component including at least one of a drug product, a diluent, a saline solution, or an IV stabilizing solution (“IVSS”) and a second component comprising at least one of the drug product, the diluent, the saline solution, and the IVSS, the first component being different than the second component. The first component is disposed in a first container in a storage state and the first container is positioned in a first compartment of the packaging housing. The second component is disposed in a second container in a storage state and the second container is positioned in a second compartment of the packaging housing. At least one of the first compartment and the second compartment may include an individual seal and wherein each of the individual seals and the first and second compartments are sterilized.
Owner:AMGEN INC

Direct in-scope suction system

The invention disclosed in this document presents a novel direct in-scope suction system designed for the retrieval of calculus fragments within the body. This system comprises two key components: a calculus fragments retrieval device and a pump unit. The calculus fragments retrieval device features a body with a single working channel that includes both an irrigation port and a suction port, which are connected to respective irrigation and suction pumps via elastomer-based rubber tubes. This setup allows for the controlled infusion of saline solution into the body lumens during lithotripsy procedures, ensuring clear visibility and fragment clearance. The retrieval device includes a trigger lever connected to a pincher tab. When the operator presses the trigger lever, the suction port is opened by releasing the pinched suction tube, increasing pressure inside the body.
Owner:BIORAD MEDISYS PTE LTD

Core-shell nano-enzyme composite spray gel dressing as well as preparation method and application thereof

The invention discloses a core-shell nano-enzyme composite spray gel dressing and a preparation method and application thereof.The dressing comprises a component A prepared from sodium alginate, N-isopropylacrylamide PNIPAM, core-shell nano-enzyme and curcumin and a component B of a divalent metal salt solution, and the component A and the component B are sprayed at the same time to form the core-shell nano-enzyme composite spray gel dressing. The preparation method of the core-shell nano enzyme comprises the following steps: mixing potassium ferrocyanide, ferric trichloride and polyvinylpyrrolidone to obtain a Prussian blue nano particle precursor solution; carrying out ultrasonic emulsification treatment and replacement on the curcumin core solution and the Prussian blue nanoparticle precursor solution; and freeze-drying to obtain the core-shell nano-enzyme. Through rapid ionic crosslinking of sodium alginate and divalent metal ions and the temperature-sensitive phase change characteristic of the temperature-sensitive polymer poly (N-isopropylacrylamide), the gel dressing is rapidly formed, the damaged skin is effectively covered and protected, the excellent antioxidant, anti-inflammatory and antibacterial capabilities are achieved, and the healing cycle of the radiodermatitis wound can be remarkably shortened.
Owner:THE PEOPLES HOSPITAL SHAANXI PROV

Method for separating and purifying 212Pb from thorium solution

PendingCN121944786Ahigh purityhigh chemical purityRare earth metal nitratesIsotope separationHigh concentrationPhysical chemistry
The invention belongs to the field of medical isotope separation and preparation, and particularly relates to a method for separating and purifying < 212 > Pb from a thorium solution, which comprises the following steps: 1) leacheate is introduced into a Pb selective adsorption column to pretreat the Pb selective adsorption column, and then < 232 > Th salt solution and leacheate are introduced in sequence; 2) continuously introducing a desorption solution into the Pb selective adsorption column, enabling the desorption solution passing through the Pb selective adsorption column to flow into the Th selective adsorption column, and collecting the outflowing desorption solution; a desorption solution only containing 212Pb is obtained; according to the method, the 212Pb in the high-concentration thorium solution can be separated and purified at the same time. While < 232 > Th impurity entrainment and pollution in a < 212 > Pb product are remarkably reduced, compared with a single-column process, the separation time is basically not increased. The separated 212Pb product has high radionuclide purity and chemical purity at the same time, and can meet related pharmaceutical requirements.
Owner:NANHUA UNIV

Oral capsule-like body product for resisting organ failure and aging

The invention provides an oral thylakoid product for resisting organ failure and aging, which is prepared by the following steps: extracting thylakoid from plants including spinach, arabidopsis thaliana, lettuce, cabbage, green algae or wheat seedlings, redissolving the thylakoid into a buffer salt solution A, and carrying out ultrasonic treatment for 10-20 minutes under the ultrasonic power of 200-500W to prepare a suspension; adjusting the concentration of the suspension to 0.5-2 mg / ml, and obtaining a nano capsule-like body with the particle size of 200-500 nm by using a microfluidic technology; the buffer salt solution A is prepared from 10 to 100 mmol / L of 4-hydroxyethyl piperazine ethanesulfonic acid (HEPES), 1 to 2 mmol / L of ethylenediamine tetraacetic acid (EDTA) disodium, 0.5 to 4 mmol / L of magnesium chloride (MgCl2), 1 to 10 mmol / L of ascorbic acid and 100 to 500 mmol / L of sapoeda sodium (SNAC), and the pH value of the buffer salt solution A is adjusted to 7.5 to 8.0; and the concentration of the capsule in the buffer salt solution A is 100-400 mg / mL. According to the product, self QPRT enzyme of the thylakoid is used for efficiently catalyzing de novo synthesis of NAD + of whole body tissues and organs, so that multiple physiological processes such as energy synthesis enhancement, oxidative stress reduction and inflammatory reaction relief are finally realized, organ failure is efficiently reversed, and organ aging is relieved.
Owner:PEKING UNIV

Method for synthesizing zeolite nanoparticles in phosphate-buffered saline, as well as related nanoparticles, suspensions, pharmaceutical compositions, and applications.

The present invention relates to a method for synthesizing nanoparticles comprising or containing at least one zeolite nanocrystal, comprising: - preparing a first composition / solution 1 comprising an aluminum source and a source of alkali metal M, particularly Na ions; - preparing a second composition / solution 2 comprising a silicon source and a source of alkali metal M, particularly Na ions, wherein compositions / solutions 1 and 2 contain no organic structuring agents; - mixing the two compositions / solutions 1 and 2; - crystallizing the mixture; and - separating the nanoparticles thus formed. According to the present invention, both the first composition / solution 1 and the second composition / solution 2 comprise the sources and alkaline phosphate buffer (PBS). The present invention also relates to the obtained nanoparticles and compositions comprising them.
Owner:UNIV CAEN +2

A portable hepatitis biomarker detection kit and a method for detecting hepatitis biomarkers.

This invention belongs to the field of biochemical detection and discloses a portable hepatitis biomarker detection kit. The kit contains a hydrogel; the hydrogel is obtained by dispersing hollow manganese dioxide in water to obtain an H-MnO2 dispersion, mixing the H-MnO2 dispersion with sodium alginate solution to obtain a mixed solution, and then adding a calcium salt solution to obtain the hydrogel. The hollow manganese dioxide is obtained by etching manganese Prussian blue analog nanoparticles with sodium hydroxide. The manganese Prussian blue analog nanoparticles are prepared from potassium ferricyanide, polyvinylpyrrolidone, and manganese salts. This invention utilizes the color change of hollow manganese dioxide in relation to TMB to construct a method for detecting hepatitis biomarkers using a smartphone to capture signals. This kit reduces the detection cost of hepatitis biomarkers, does not require large instruments, and is highly portable and widely applicable, possessing great potential as a novel point-of-care testing device.
Owner:CHINA PHARM UNIV

Injectable self-healing self-assembling herring sperm extract hydrogel, and preparation method and application thereof

The application discloses an injectable self-healing self-assembling protamine extract hydrogel and a preparation method and application thereof, and belongs to the technical field of hydrogel materials and wound repair. The hydrogel is prepared by mixing protamine extract and a crosslinking agent solution; the crosslinking agent solution comprises a salt solution with a final concentration of 0.01-4.5 M, 0.01-0.1 M sodium citrate and 0.01-0.1 M sodium bicarbonate; the protamine extract is mixed with the crosslinking agent solution at different proportions (1%-50%, w / v%) and is stirred at 20-35 DEG C until complete gelation; and a series of hydrogels can be prepared after multiple freeze-thaw cycles. The hydrogel prepared by the application has good self-healing, injectable characteristics, blood compatibility and tissue regeneration capacity, and has a wide application prospect.
Owner:OCEAN UNIV OF CHINA

Zedoary turmeric oil / oxidized regenerated cellulose embolization microspheres, preparation method therefor, and use thereof

The present application relates to the technical field of pharmaceutical formulations and provides zedoary turmeric oil / oxidized regenerated cellulose embolization microspheres, a preparation method therefor, and use thereof. In the present application, with zedoary turmeric oil as a core solution, a mixed solution of oxidized regenerated cellulose, sodium alginate, and gelatin as a shell layer solution, and a divalent or trivalent metal salt solution as a receiving solution, the zedoary turmeric oil / oxidized regenerated cellulose embolization microspheres are prepared by means of a coaxial electrostatic spraying method. The zedoary turmeric oil / oxidized regenerated cellulose embolization microspheres prepared in the present application have a marked core-shell structure, are uniform in size and good in sphericity, can effectively hide the pungent smell of zedoary turmeric oil, improves the stability of zedoary turmeric oil, and enables directed embolization in tumor blood vessels, thereby reducing toxic and side effects. In addition, the embolization microspheres prepared in the present application have good mechanical properties; therefore, the microspheres can effectively resist deformation under compression and prevent fragmentation within the body, enabling firm embolization of zedoary turmeric oil at the tumor vascular site.
Owner:SHANDONG SECOND MEDICAL UNIV

Transcervical access systems for intrauterine fluid exchange, e.g., placement of hydrogels formed in situ.

PendingJP2026123216ACol uterinEndoluminal surgery
This invention provides a transcervical access system for moving fluids transcervically. [Solution] The transcervical access system 100 is effective in transferring a wide range of fluids into the uterine cavity, including the delivery of a hydrogel precursor, saline solution, and imaging fluid. The transcervical access system 100 is also effective in removing fluids, such as residual bodily fluids, residual fluids from procedures, or tissue from the uterine cavity. The transcervical access system 100 includes a flow limiter, such as an outflow limiter 106 and / or a cervical plug. A method of using the transcervical access system 100 involves using the transcervical access system 100 to transcervically access the uterine cavity and to install the hydrogel. The transcervical access system 100 and related methods are useful in preventing adhesions after intrauterine procedures by providing a biodegradable hydrogel within the uterine cavity, including the cervix.
Owner:PRAMAND LLC

Equipment for settling solid particles in saline solution

The utility model relates to the technical field of brine solution sedimentation, in particular to sedimentation equipment for solid particles in brine solution, which comprises a main box body, an overflow plate is arranged in an inner cavity of the main box body, and the inner cavity of the main box body is divided into a lower-layer sedimentation cavity and an upper-layer overflow cavity by the overflow plate; and overflow ports which are distributed at intervals are formed in the overflow plate. By designing the settling equipment for the solid particles in the saline solution, which comprises the main box body, the overflow plate, the liquid inlet pipe and the liquid discharge pipe, the effective separation of the solid particles and the saline solution is realized. Overflow ports distributed on the overflow plate at intervals allow clear saline water to enter the upper overflow cavity and be discharged through a liquid discharge pipe, and solid particles sink to the bottom under the action of gravity. An upper baffle plate and a lower baffle plate are arranged in the lower settling cavity, so that the flowing time of the saline water is prolonged, the settling efficiency of solid particles is improved, and the purity of the discharged saline water solution is ensured.
Owner:HUBEI LANTIAN SALT PLANT

Aqueous solutions of dantrolene

The present invention relates to aqueous saline solutions comprising dantrolene and optionally at least one additional active ingredient, such as botulinum neurotoxin, and their use for various therapeutic and / or aesthetic purposes. The solutions can be administered in any suitable manner, but have the advantage of being particularly well-suited for intramuscular injection.
Owner:FASTOX PHARM SA

Closed preparation device for chemotherapeutic drugs

The utility model relates to the technical field of chemotherapeutic drug preparation, and discloses a closed chemotherapeutic drug preparation device, which comprises an installation cylinder, a powder bag and a liquid bottle are arranged in the installation cylinder, the powder bag and the liquid bottle are arranged up and down, a configuration structure is arranged in the installation cylinder, and the configuration structure comprises two partition plates fixed in the installation cylinder. Through the arrangement of the configuration structure, a worker puts a powder bag into the mounting cylinder, slides the powder bag into the corresponding partition plate to be clamped, inserts a first needle head into a connector of the powder bag, slides a second needle head into the partition plate above to be clamped, puts a liquid bottle into the mounting cylinder, penetrates the second needle head into the liquid bottle, and flows liquid into the powder bag through the needle heads and a conveying pipe; preliminarily mixing with the medicinal powder; then a motor is started to drive a cam to rotate and push a movable plate to lift in a reciprocating manner, vibration is applied to the powder bag under the action of a spring, dissolution and mixing of medicine powder and saline water are accelerated, rapid and uniform preparation is achieved, and the chemotherapeutic medicine preparation efficiency and effect are improved.
Owner:NANJING GENERAL HOSPITAL NANJING MILLITARY COMMAND P L A

Pester drainage and removal device

The utility model discloses a fester drainage and removal device, which belongs to the technical field of medical instruments and comprises an injector, a cleaning and drainage component for cleaning, draining and removing fester and a rotary fixing component for adhering and fixing the cleaning and drainage component. The cleaning drainage assembly comprises a double-channel cleaning assembly and a negative pressure drainage assembly, the double-channel cleaning assembly is installed on the right side of the injector, the negative pressure drainage assembly is installed on the right side of the double-channel cleaning assembly, and the rotary fixing assembly is installed on the left side of the negative pressure drainage assembly. After the double-channel cleaning assembly and the negative pressure drainage assembly are inserted into an esophageal anastomosis fistula, the rotary fixing assembly is attached to the neck, meanwhile, the negative pressure drainage assembly is rotationally fixed, and falling is prevented; the syringe extracts and injects normal saline through pipeline switching of the double-channel cleaning assembly, the negative pressure drainage assembly drains out the normal saline and pus after cleaning through negative pressure and collects the normal saline and the pus, and effective cleaning of the flaccid stoma is achieved.
Owner:CHINESE PEOPLES LIBERATION ARMY ARMY SPECIAL MEDICAL CENTER

Preparation method of plastic bone grafting material and plastic bone grafting material

The invention relates to a preparation method of a plastic bone grafting material and the plastic bone grafting material.The preparation method comprises the following steps that a, phenyl phosphate lithium salt is dissolved in a phosphoric acid buffer salt solution to obtain a mixed solution, and Ge MA is dissolved in the mixed solution to obtain a Ge MA gel solution; b, bone meal and the Ge MA gel solution are subjected to a cross-linking effect, so that the bone meal and the Ge MA gel solution are fully mixed, then light source irradiation is conducted, the bone meal hydrogel bone grafting material is obtained, and the particle size of the bone meal is 0.25-0.5 mm. According to the preparation method of the plastic bone grafting material, provided by the invention, the bone meal and the Ge MA gel solution are subjected to cross-linking and then subjected to light source irradiation, so that the bone meal and the hydrogel are uniformly mixed, the compatibility of an organic phase and a bone meal particle interface is good, and the prepared plastic bone grafting material is relatively high in plasticity and good in osteoinductivity; and the cell adhesion rate is high.
Owner:XIAN MEDICAL UNIV +1

Devices and methods for treating lung tumors

A method to treat a human patient including: advancing a catheter through a natural airway of the patient and positioning a distal portion of the catheter in the natural airway of a lung of the patient to a target region in the lung, injecting a conductive hypertonic saline solution having a concentration of at least 5% of sodium chloride by weight / volume from the distal portion of the catheter into the target region; delivering energy from the distal portion into the conductive hypertonic saline solution in the target region, wherein the energy heats the liquid in the portion of the airway, and ablating the target region with the heated liquid.
Owner:ZIDAN MEDICAL INC

Water injection connecting channel structure for bipolar electric coagulation forceps and bipolar electric coagulation forceps

The utility model relates to the technical field of medical instruments, in particular to a water injection connecting channel structure for bipolar electric coagulation forceps, which is provided with a water injection shell, the water injection shell is mounted between two forceps bodies, a water inlet and a water outlet are formed in the water injection shell, a plunger is arranged in the water injection shell, two sealing pieces are arranged on the plunger, and the two sealing pieces are connected with the water injection shell. The pressing action of the forceps body and the movement of the plunger are directly associated, flowing of normal saline is controlled by simply pressing or releasing the forceps body, the operation process is simplified, the operation burden of a doctor in an operation is reduced, the doctor does not need to distract to operate a valve, the doctor can concentrate on the operation, and the operation efficiency is improved. According to the water injection connecting channel structure for the bipolar electric coagulation forceps, through automatic control, the operation concentration is improved, human errors are reduced, a more convenient, reliable and efficient normal saline control scheme is provided for doctors, and therefore the operation quality and safety are improved.
Owner:WEIHAI SAIWEI MEDICAL TECH CO LTD

Water-based drilling fluid system capable of resisting high-concentration mixed saline solution and preparation method of water-based drilling fluid system

The invention discloses a water-based drilling fluid system resistant to a high-concentration mixed saline solution and a preparation method of the water-based drilling fluid system, and belongs to the technical field of drilling fluids. According to the water-based drilling fluid system resistant to the high-concentration mixed saline solution, the influence of cations with different valence states and an underground high-temperature and high-pressure environment on the rheological property, the filtration performance and the like of the drilling fluid is fully considered, and two high-valence cation-resistant drilling fluid filtrate reducers are introduced; the technical problems that a conventional drilling fluid is poor in rheological property, poor in filtrate loss reduction performance, poor in system stability and the like in high-concentration mixed salt water are solved. The system can meet the requirement for rapid drilling of a stratum at the ground temperature of 150 DEG C and the high salt ion concentration, can still keep good capacities of carrying rock, lubricating, blocking and preventing collapse, inhibiting clay hydration and dispersion and the like in a high-concentration mixed salt water solution, does not need precise instruments and equipment, is simple and easy to operate, low in cost and good in economical efficiency, can be prepared and used at any time, and has wide application prospects. The method is suitable for drilling conditions.
Owner:CHINA NAT PETROLEUM CORP +1

Plasticised superporous hydrogel

The invention provides a process for preparing a plasticised superporous hydrogel material comprising subjecting initial hydrogel material to treatment with an acidic solution, an optional treatment with a monovalent metal salt solution, freeze drying and plasticisation. Optionally, the process of the invention produces moulded plasticised superporous hydrogel material bodies that have one or more through-holes formed therein. The plasticised superporous hydrogel material of the present invention may be formulated as a suitable oral dosage form for use an appetite suppressant and for use to deliver a pharmaceutical and / or nutraceutical into a human or animal body.
Owner:OXFORD MEDICAL PROD LTD

Method for generating nitric oxide gas and apparatus therefor

The application discloses a method for generating nitric oxide gas, and belongs to the field of gas preparation and medical treatment, and is characterized in that the method for generating nitric oxide gas is to mix liquid medicament with solid medicament, to make the liquid medicament and the solid medicament react chemically, so as to generate nitric oxide gas with a certain concentration, the effective component of the solid medicament is nitrosyl iron sulfate, and the liquid medicament is one or a mixture of several kinds of alkali solution or slurry and salt solution or slurry. The application further discloses a corresponding device for generating nitric oxide gas.
Owner:ZHEJIANG NOXING TECHNOLOGY CO LTD

A saline infusion device suitable for PICCO

ActiveCN117547239BSaline solutionsSurgery
This invention provides an infusion device for PICCO-compatible saline solution, comprising a syringe, a sealing assembly, and a transmission mechanism. The syringe head has an inlet tube and an outlet tube communicating internally. The syringe head also has a groove connecting the inlet and outlet tubes. The sealing assembly is slidably connected within the groove and can seal either the inlet or outlet tube. The transmission assembly is rotatably mounted on the syringe head and connected to the syringe plunger. Pulling the plunger outward causes the sealing assembly to slide intermittently via the transmission assembly, moving it from sealing the outlet tube to sealing the inlet tube when pushed to its maximum distance; pushing inward reverses this process. This infusion device for PICCO-compatible saline solution allows for changing the sealing status of the inlet and outlet tubes through outward and inward pulling, respectively, eliminating the need to repeatedly move the syringe interface. The inlet tube is connected to a cold water bag, and the outlet tube is connected to a three-way connector.
Owner:ARMY MEDICAL UNIV

Method for synthesizing zeolite nanoparticles in phosphate-buffered saline - related nanoparticles, suspensions, and pharmaceutical compositions

The present invention relates to a method for synthesizing nanoparticles comprising or containing at least one zeolite nanocrystal, comprising: - preparing a first composition / solution 1 comprising an aluminum source and a source of alkali metal M, particularly K ions; - preparing a second composition / solution 2 comprising a silicon source and a source of alkali metal M, particularly K ions, wherein compositions / solutions 1 and 2 contain no organic structuring agents; - mixing the two compositions / solutions 1 and 2 together; - crystallizing the mixture; and - separating the nanoparticles thus formed. According to the present invention, both the first composition / solution 1 and the second composition / solution 2 consist of the sources and phosphate-buffered saline. The present invention also relates to a colloidal suspension of the obtained nanoparticles and a pharmaceutical composition containing the nanoparticles.
Owner:UNIV CAEN +2

A chitosan-modified clay-based aerogel wound dressing and a preparation method thereof

The present application relates to the technical field of wound dressing, and particularly relates to a chitosan modified clay-based aerogel wound dressing and a preparation method thereof. The preparation method comprises the following steps: S1: adding clay minerals into deionized water to prepare a slurry, and adding acetic acid while stirring to obtain a clay mineral slurry; S2: dissolving chitosan in an acetic acid solution to prepare a chitosan sol; S3: continuously stirring and mixing the clay mineral slurry and the chitosan sol to obtain a sol; S4: immersing the sol in a metal cation solution first, and then immersing the sol in an anion salt solution to obtain a standing product; and S5: freeze-drying the standing product to obtain a composite aerogel. The present application successfully constructs a three-dimensional porous aerogel dressing, which not only retains the strong hemostatic ability of clay, but also significantly enhances the mechanical strength and antibacterial performance, and exhibits great potential in the treatment of high-exudation complex wounds such as diabetic foot ulcers and infected wounds.
Owner:CHINA UNIV OF GEOSCIENCES (WUHAN)

Brine blending device for erythrocyte osmotic brittleness test

The utility model discloses a brine blending device for a red blood cell osmotic brittleness test. The brine blending device comprises a main shell and a position mark sensing unit, a salt water blending unit and a center alignment unit; a master controller; a to-be-loaded test tube group is placed on the bottom placing table, the center alignment unit is used for placing the to-be-loaded test tube group in the middle position, the position mark sensing unit is used for measuring and calculating the distance between the head test tube and the tail test tube of the test tube group so as to guide the horizontal moving unit to rapidly move to the position over the test tubes relative to the center of the device, and the visual camera and the injection angle adjusting assembly are used for adjusting the injection angle. The injection head is aligned with a test tube opening, and the metering pump is started to inject saline water and distilled water into the test tube according to a fixed proportion. Based on a saline water filling mode of mobile hovering injection, a horizontal moving unit is arranged to realize movement of an injection head above a test tube group, so that the problem of material resource waste caused by a traditional one-tube one-path scheme is solved; in addition, by arranging a visual camera and an ejection angle adjusting assembly, the technical risk that saline water is injected out of the test tube is avoided to a great extent.
Owner:TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH

Compositions and methods for the treatment of cellulite

Described herein are methods and formulations for treating, inhibiting, or ameliorating cellulite. Aspects described herein relate to formulations including a saline solution, reactive oxygen species, a rheology agent, an emollient, and a pH modifier and methods of using these formulations for treating, ameliorating, or inhibiting cellulite.
Owner:REOXCYN LLC

Preparation method of (R)-(1-([1, 1 '-biphenyl]-4-yl)-3-oxopropane-2-yl) tert-butyl carbamate

The invention relates to the technical field of preparation of tert-butyl carbamate, in particular to a preparation method of (R)-(1-([1, 1 '-biphenyl]-4-yl)-3-oxopropane-2-yl) tert-butyl carbamate. Comprising the following steps: S1, taking a four-mouth bottle, adding 1780 g of dichloromethane, 165 g of (R)-tert-butyl (1-([1, 1 '-biphenyl]-4-yl)-3-hydroxypropane-2-yl) carbamate, 1.6 g of TEMPO and 2 g of tetrabutylammonium bromide into the four-mouth bottle, and stirring the four-mouth bottle, the dichloromethane, the (R)-tert-butyl (1-([1, 1'-biphenyl]-4-yl)-3-hydroxypropane-2-yl) carbamate, the TEMPO and the tetrabutylammonium bromide; s2, 33.5 g of a sodium bromide solution and 146 g of clear water of a phosphoric acid mixed salt solution are added into the four-opening bottle after stirring in the step S1, and liquid in the four-opening bottle is cooled to a specified temperature; s3, sodium hypochlorite with the available chlorine content being 9-10% is dropwise added into the four-opening bottle cooled in the S2; and S4, after dripping in the step S3 is completed, preserving the heat of the liquid in the four-mouth bottle, and adding 385 g of a sodium thiosulfate solution into the bottle for quenching reaction. And S5, sampling and detecting. The pH value buffering agent of a phosphate system, namely a sodium dihydrogen phosphate-disodium hydrogen phosphate composite salt system, is used, and the yield is 90-96%.
Owner:CHONGQING JICHENG BIOMEDICAL TECHNOLOGY CO LTD

Single-phase edible microcarrier for the three-dimensional culture of stem cells for the preparation of a cultured meat product

The present invention relates to a single-phase, spherical edible microcarrier for the three-dimensional culture of stem cells intended for the preparation of cultured meat. The microcarrier comprises a homogeneous mixture of edible ionic polysaccharide (0.375-1.5%), edible protein (1-2.5%), edible polymer (0.025-0.1%) and water (95.9-98.6%). The invention also relates to a method for preparing these microcarriers by mixing three solutions: ionic polysaccharide in saline solution, edible protein in saline solution and edible polymer in water. The mixture is subjected to a process involving microspraying or electrospraying with calcium chloride in order to form spherical microcarriers of 50-300 micrometres. The design of the single-phase, spherical edible microcarrier simplifies the production of cultured meat by dispensing with the need for core-shell structures, thereby improving cell anchorage efficiency and facilitating cell recovery.
Owner:SIGMA ALIMENTOS S A DE

Method for producing caviar or a caviar-like product from live mature eggs of fish or crustaceans

A method for producing caviar or a caviar-like product from live, mature eggs of fish or crustaceans, wherein the eggs are in a fertile but unfertilized state and have a natural potassium content in the egg plasma, includes: treating the eggs in a saline solution which does not damage the eggs and subsequently treating the live, mature eggs in a solution of water and potassium in a concentration which does not damage the eggs and does not change the eggs' potassium content. The water is deionized prior to the addition of a potassium donor for forming a cationic component in the solution, the solution has a temperature that does not damage the eggs, and the eggs are treated in the solution for a duration of a potassium exposure time until an egg envelope of the eggs obtains a desired elastic stabilization.
Owner:ALFRED WEGENER INST HELMHOLTZ ZENT FUR POLAR & MEERESFORSCHUNG