The current invention relates to a pharmaceutical composition for local or parenteral administration, more specifically an
injectable solution comprising of an
amino acid composition dissolved in purified
hyaluronic acid or a salt or ester thereof, wherein said
hyaluronic acid has a molecular weight between 500 kDa and 4000 kDa and wherein said
injectable solution comprises a pH between 6.4 and 7.8. In a further aspect, the present invention also relates to use of aforementioned pharmaceutical composition in the treatment of a
musculoskeletal disease, such as
osteoarthritis, in a subject.