616 results about "Injection solution" patented technology

The invention relates to the technical field of medical materials, in particular to an injection composition for endoscopic submucosal dissection and a preparation method and application thereof. The injection composition is prepared from the following raw materials: 1 to 5 w / v percent of sodium hydroxymethyl starch, 0.1 to 10 w / v percent of acetylcysteine, 0.2 to 4 w / v percent of polyvinylpyrrolidone, 0.001 to 0.1 w / v percent of coloring agent and the balance of phosphate buffer solution. The injection composition disclosed by the invention can be directly injected under mucous membranes, plays a role in upheaving diseased regions, has the advantages of long maintenance time and high upheaving degree, and has the effects of stopping bleeding and promoting wound healing.

A pen-type full-automatic precision injection system, comprising: a support table (1), an injection assembly (2), a connecting device (3), a control console (4), and a control switch (5). The control console (4) is arranged on the support table (1), the injection assembly (2) is connected to the control console (4) by means of the connecting device (3), and the control switch (5) can control the injection assembly (2) by means of the control console (4). The injection assembly (2) comprises an auxiliary positioning device (21), a housing (22), a drug storage device (23), a first movement assembly (24), and a second movement assembly (25). The auxiliary positioning device (21) is connected to a left wall of the housing (22). The first movement assembly (24) can drive an outer barrel (231) of the drug storage device (23) to move left and right, an injection needle (232) of the drug storage device (23) can penetrate through the housing (22) and the auxiliary positioning device (21) to pierce the skin of a human body, and the second movement assembly (25) can push a pushing rod (233) of the drug storage device (23) to move to push an injection liquid into the human body. The pen-type full-automatic precision injection system can achieve functions such as automatic injection, adjustment of the injection depth, precise control over the needle piercing depth, precise control over the injection dose, precise control over the injection rate, bubble detection, and pressure detection during injection.

The invention provides a diphenhydramine hydrochloride injection and a preparation method thereof. According to the preparation method, the diphenhydramine hydrochloride injection with stable pH value, stable chemical property and sterility assurance level SAL less than or equal to 10 <-6 > can be obtained by controlling the material of a liquid medicine pipeline and the water resistance of a medium borosilicate glass ampoule. The diphenhydramine hydrochloride injection does not contain preservatives and cannot generate safety risks.

The invention belongs to the field of medicine, and relates to application of polydocanol in preparation of medicine for treating bromhidrosis through dispersion gridding subcutaneous multipoint continuous injection application, the polydocanol is a polydocanol injection, and each milliliter of the injection contains 5-30 mg of polydocanol. The invention further provides a medicine for treating bromhidrosis through dispersion gridding subcutaneous multipoint continuous injection application. The medicine comprises polydocanol and pharmaceutically acceptable auxiliary materials. The invention has the advantages of small trauma, simplicity and convenience in operation, high safety, longer treatment effect maintenance time and the like, and the long-term relieving effective rate is greater than 80%.

The invention belongs to the field of chemical medicine analysis, and particularly relates to a method for determining the content of impurities in phloroglucinol trimethyl ether. According to the method provided by the invention, the excessive methylation impurities (2, 4, 6-trimethoxytoluene, 2, 4, 6-trimethoxyxylene and 2, 4, 6-trimethoxytrimethylbenzene) generated in the methylation process can be detected, and the excessive methylation impurities are prevented from being further transferred and existing in a phloroglucinol trimethyl ether raw material medicine and a final product phloroglucinol injection preparation. Researches on specificity, accuracy, precision, limit of detection, limit of quantitation, linear range, durability and the like of the method prove that the method is suitable for measuring the content of the over-methylated impurities in the phloroglucinol trimethyl ether.

The invention relates to the technical field of analytical chemistry, and particularly discloses an HPLC (High Performance Liquid Chromatography) detection method for related impurities in a vitamin B6 injection. The invention provides an HPLC detection method for related impurities in vitamin B6 injection. The HPLC detection method comprises the following steps: carrying out separation detection on a to-be-detected sample by adopting a chromatographic column taking octadecylsilane chemically bonded silica as a filler and a mobile phase gradient elution method; the mobile phase A is 0.04% sodium pentane sulfonate solution-methanol with the volume ratio of 95: 5, and the pH value of the 0.04% sodium pentane sulfonate solution is adjusted to 3.0 by adopting phosphoric acid; the mobile phase B is methanol. The HPLC detection method provided by the invention can detect 13 impurities in the vitamin B6 injection at the same time, the detection specificity is high, the sensitivity is high, the separation degree is good, and the quality of the vitamin B6 injection can be effectively controlled when the detection method is applied to production of the vitamin B6 injection.

The invention discloses an oxytetracycline injection and a preparation method thereof, and relates to the technical field of pharmaceutical preparations, the oxytetracycline is firstly micronized, then sprayed with water, frozen, heated and dried, soaked in a solution containing a surfactant, taken out and dried, and pretreated oxytetracycline is obtained; s2, water for injection is taken and heated, an antioxidant is added for dissolution, then a complexing agent is added, stirring is performed for dissolution, and a first solution is obtained; adding an organic solvent into the first solution, heating, adding the pretreated oxytetracycline, stirring and dissolving to obtain a second solution; adding a stabilizer into the second solution, and adjusting the pH value; and then supplementing the water for injection to obtain the injection. The oxytetracycline raw medicine powder is micronized to a specific particle size range, then freeze drying is performed to make the oxytetracycline raw medicine powder loose and porous, and compatibilization of the surfactant is further combined, so that the solubility and the stability of the oxytetracycline raw medicine powder are greatly improved in the subsequent injection preparation process.

The invention provides a silibinin mixed micelle injection as well as a preparation method and application thereof, and belongs to the technical field of pharmaceutical preparations. The cholate / lecithin mixed micelle system constructed by adopting specific cholic acid and phospholipid has good stability, can be well compatible with the silibinin so as to well encapsulate the silibinin, can obviously improve the solubility of the silibinin, has higher safety under the condition of ensuring the stability of the silibinin, and can be used for preparing a medicine for treating the silibinin. Therefore, the bioavailability of the silibinin is greatly improved. According to the invention, a shearing dispersion method is adopted to prepare the mixed micelles, and the mixed micelles with high drug loading capacity, clarification and good stability for silibinin are formed by destroying and shearing the raw and auxiliary materials in a molecular level, so that the mixed micelles have better physical and chemical stability, the drug quality is easier to control, the process is more simplified, the clinical medication is safer and the cost is lower; and the accessibility of the medicine is improved.

The invention relates to the technical field of drug analysis and detection, and particularly discloses a method for detecting the residual quantity of glucose in an irinotecan hydrochloride liposome injection. According to the method, irinotecan hydrochloride in the liposome is fully separated from small molecular substances such as glucose and sodium chloride by adopting an ultrafiltration method, then, a Waters XBridge BEH HILIC chromatographic column is adopted, a mixed solution of an acetate buffer solution with the pH value of 3.8-4.2 and acetonitrile is used as a mobile phase, and the content of irinotecan hydrochloride in the liposome is detected in an isocratic elution mode by adopting a high performance liquid chromatography method. The effective separation of glucose, sodium chloride, 4-hydroxyethylpiperazine, sucrose octasulfate potassium and other substances is realized, and the condition of the glucose residue in the irinotecan hydrochloride liposome is accurately detected. The invention provides a reliable guarantee for improving and better controlling the quality of the irinotecan hydrochloride liposome injection product, and has very important significance for improving the medication safety.

The invention belongs to the technical field of medicines, and particularly relates to a posterior pituitary injection and a preparation method thereof. The posterior pituitary injection comprises the following raw materials in concentration: 6 units / ml of posterior pituitary powder, 1-5 mg / ml of trichlorobutanol and pharmaceutically acceptable acid, wherein the dosage of the pharmaceutically acceptable acid ensures that the pH value of the posterior pituitary injection is adjusted to 3.0-4.0. The invention further provides a preparation method of the posterior pituitary injection. According to the invention, the dissolving capacity of the auxiliary material trichlorobutyl alcohol in water can be improved, so that trichlorobutyl alcohol cannot be separated out under the condition of normal temperature or refrigeration. According to the invention, the quality of a medicinal preparation and the safety of medication can be better ensured, and the method has a good application prospect.

The invention discloses a terbinafine hydrochloride needleless injection, a transdermal injection for treating superficial fungal infection and an administration device of the transdermal injection, belongs to the technical field of pharmaceutical preparations, and successfully develops the terbinafine hydrochloride needleless injection which takes benzyl alcohol and ethanol as auxiliary materials, the invention provides a terbinafine hydrochloride needleless injection or an injection administration device thereof, which is used for preparing the terbinafine hydrochloride needleless injection, and proves that a prescription containing low-concentration ethanol can have good safety and excellent infiltration and absorption promoting capability, and the medicine can quickly reach a focus part and has long effective action time. The invention also provides the administration device of the terbinafine hydrochloride needleless injection or the injection thereof. According to the dosing device, the replaceable injection head and the injection assembly are used, cross infection can be reduced, and the purity of liquid medicine is kept.

The invention provides a preparation method of an edaravone and dextroborneol injection, the injection comprises edaravone, dextroborneol, propylene glycol and sodium pyrosulfite, in the preparation process, the propylene glycol accounting for 60%-85% of the prescription dosage and water accounting for 5%-25% of the prescription dosage are injected into a liquid preparation tank according to the volume ratio, the mixture is heated to 50-60 DEG C, edaravone is added and stirred to be dissolved, and the edaravone and dextroborneol injection is prepared. The preparation method comprises the following steps: dissolving propylene glycol in the remaining prescription dosage, adding dextroborneol which is dissolved by propylene glycol in the remaining prescription dosage in advance, uniformly stirring, adding water which is close to a constant volume, cooling to 25 DEG C or below, adding sodium pyrosulfite, adjusting the pH value to 4.0-5.0, and fixing the volume to a full volume. According to the preparation method of the edaravone dextroborneol injection, auxiliary materials in a specific proportion are matched with the preparation steps, the problem that raw material medicines are extremely easy to separate out in the preparation process is solved, the requirement of the preparation process for an industrial liquid preparation tank is low, industrial operation is convenient, and the preparation cost is low.

The invention mainly relates to a method for determining related substances of doxofylline injection, using high performance liquid chromatography, using octadecylsilane bonded silica gel as a filler; mobile phase A is a phosphoric acid aqueous solution with a pH of 1.5-3.5, and mobile phase B is acetonitrile, and gradient elution is performed. The detection method can completely separate impurities 1-9 in doxofylline injection, with a separation degree greater than 1.5, good system applicability, and the method has high specificity, accuracy and reproducibility, etc., is easy to operate, has no damage to the chromatographic column, and can be used for analysis, detection and quality control of doxofylline injection in industrial production.

The invention discloses a dexmedetomidine and propofol combined reagent and a combination method, and relates to the technical field of combined use of anesthetic drugs. According to the method, firstly, dexmedetomidine is subjected to intravenous pump injection within 5-15 minutes according to the dosage of 0.5-1.0 mu g / kg, propofol is given within 2 minutes after the dexmedetomidine is subjected to general anesthesia, and the dosage of the propofol can be reduced by 10%-50% compared with that of propofol which is independently used. Through pretreatment of dexmedetomidine, the anesthetic effect of propofol can be enhanced, adverse reactions such as blood pressure drop and respiratory depression can be effectively reduced, and anesthetic safety and controllability are improved. The combined reagent comprises independent containers for respectively loading the dexmedetomidine injection and the propofol emulsion, and can be packaged by adopting a double-cavity pre-filled injector, and sequential injection is realized through a controllable opening mechanism, so that unstable emulsification and titer change caused by physical mixing of medicines are avoided.

An anti-aging injection composition, an anti-aging injection, and use thereof. The anti-aging injection composition contains hyaluronic acid or a salt thereof, glycine, proline, lysine hydrochloride, and leucine, which can synergistically promote the generation of collagen and elastin in the skin, thereby helping to correct skin wrinkles, improve skin elasticity, and enhance skin radiance. The anti-aging injection composition can be used to prepare an anti-aging injection, which has the effect of resisting skin aging.

The invention provides a tigorasone fumarate injection and a preparation method thereof, and belongs to the technical field of medicines. The injection provided by the invention is prepared from tigorasone fumarate, a pH (Potential of Hydrogen) regulator and water for injection. The tegorasone fumarate injection has various medicine applications of inhibiting gastric acid secretion, promoting gastric ulcer healing and preventing reflux esophagitis. The injection can tolerate terminal sterilization, and is high in safety and good in stability.

The invention provides an urapidil hydrochloride injection and a preparation method thereof, and particularly relates to the field of medicines. The urapidil hydrochloride composition comprises the following components in w / v: 0.4-0.6% of urapidil hydrochloride; 9-11% of a stabilizer; 0.03 to 0.05 percent of anhydrous disodium hydrogen phosphate; 0.1-0.3% of sodium dihydrogen phosphate monohydrate, and the balance of water for injection, which is supplemented to 100%. The defects in the prior art are overcome, the cost is saved, meanwhile, the impurity level of the urapidil hydrochloride injection after sterilization is reduced, the liquid medicine temperature is reduced in the liquid preparation and filling processes, meanwhile, the inert gas is filled, the influence of metal ions in a production assembly is greatly reduced, and the production efficiency is improved. The levels of impurities C and D in the finished product after the urapidil hydrochloride injection is sterilized are reduced; the prepared urapidil hydrochloride injection is low in impurity level and high in stability, the quality of the urapidil hydrochloride injection meets the requirements of current laws and regulations, and the urapidil hydrochloride injection is superior to a reference preparation.

The present invention discloses an N-acetylcysteine xylitol injection and its preparation method, which comprises raw materials with the following mass-volume ratios: 0.020 - 0.035 g / mL of N-acetylcysteine, 0.015 - 0.030 g / mL of xylitol, 0.005 - 0.010 g / mL of pH regulator, and the balance being injection water. The method of the present invention can reduce the oxidation and degradation of N-acetylcysteine during the preparation of the medicinal solution by controlling the dissolution concentration, temperature and range of the residual headspace oxygen amount of N-acetylcysteine, and selecting a pH regulator with an appropriate concentration to control the pH value of the medicinal solution and controlling the preparation time, thereby improving the stability of the product quality and controlling the generation of related substances. The present invention significantly improves the quality stability of the N-acetylcysteine xylitol injection, ensures the safety of patients' medication, and makes the product have broad application prospects and value.

The invention provides a method for improving product quality by optimizing a posterior pituitary injection purification process, and belongs to the technical field of medicines. According to the method, glacial acetic acid is adopted as a dissolving medium, and the influence of the concentration of glacial acetic acid, the extraction temperature and the filtering condition on the posterior pituitary injection is investigated, so that visible foreign matters and macromolecular substances are effectively removed, and the potency, the specific activity and the potency ratio of the product are improved. Besides, the method is simple to operate, ensures the stability and curative effect of the product, is suitable for industrial production of the posterior pituitary injection, and has important significance for improving the drug quality and meeting clinical requirements.

The utility model relates to the technical field of flushing and sealing tubes, and provides an automatic medicine injection flushing and sealing tube device capable of adding medicine, the automatic medicine injection flushing and sealing tube device comprises a double-cavity injector, two medicine adding devices and a tube pushing device, the double-cavity injector is provided with two injection cavities, the two injection cavities are used for containing injection liquid, the two medicine adding devices are communicated with the two injection cavities respectively, the two medicine adding devices are used for containing medicine, and the tube pushing device is used for pushing the medicine into the double-cavity injector. The tube pushing device is detachably connected with the double-cavity injector, and the tube pushing device is used for driving the double-cavity injector to perform injection. According to the double-cavity injector, the tube pushing device and the medicine adding devices are arranged, so that the double-cavity injector can be driven by the double-cavity injector to push the tube, automatic tube washing and tube sealing or injection can be achieved, the same or different medicines can be added into the two injection cavities through the two medicine adding devices communicated with the two injection cavities respectively in the using process, and the double-cavity injector is convenient to use. Therefore, the use requirements of medical staff in different scenes can be flexibly met.

The invention provides a vitamin B6 injection and a preparation method thereof, and particularly relates to the field of medicines. Comprising 10 g of vitamin B6, a proper amount of a pH regulator, a proper amount of nitrogen and the balance of water for injection, the volume is fixed to 100 ML, and the pH is 2.0-3.0. The method comprises the following steps: S1, adding 70% of injection water into a liquid preparation tank, controlling the water temperature to be less than 40 DEG C, and filling nitrogen into the liquid preparation tank and a pipeline; s2, weighing the vitamin B6 according to the prescription dosage, putting the vitamin B6 into a liquid preparation tank, and stirring for 30-60 minutes at the temperature of 10-40 DEG C to dissolve the vitamin B6; s3, adding a pH (Potential of Hydrogen) regulator with the concentration of 0.01 mol / L to 1 mol / L into the solution obtained in the S2; adjusting the pH (Potential of Hydrogen) to 2.0 to 2.8; s4, fixing the volume of the solution obtained in S3 to 100% of the total volume, and stirring for 15-30 minutes after fixing the volume; s5, sterilizing and filtering the stirred solution, and filling nitrogen; and S6, sterilizing the filled and sealed sample at 121 DEG C for 12 minutes to finally obtain the vitamin B6 injection product. Degradation of related substances of liquid medicine is reduced by controlling a liquid medicine production process, and the more stable vitamin B6 injection is obtained.

The invention discloses a liquid chromatography method for measuring 5-hydroxymethylfurfural in a calcium gluconate and sodium chloride injection. The method comprises the following steps: measuring the calcium gluconate and sodium chloride injection as a test solution; weighing 5-hydroxymethylfurfural, and adding water to dilute the 5-hydroxymethylfurfural to form a reference solution; carrying out continuous sample introduction on the liquid chromatograph by using the reference substance solution to obtain a system applicability solution chromatogram; when the chromatogram of the applicable solution of the system meets the standard, measuring the test solution and the reference solution, respectively injecting the test solution and the reference solution into a liquid chromatograph, and recording the chromatograms; the content of 5-hydroxymethylfurfural in the calcium gluconate and sodium chloride injection is obtained through a 5-hydroxymethylfurfural content calculation formula. The method has the advantages of strong specificity, high sensitivity, good precision, strong durability and the like, and can quantitatively detect 5-hydroxymethylfurfural in the calcium gluconate and sodium chloride injection, so that the safety of clinical medication of the calcium gluconate and sodium chloride injection is improved.

The utility model discloses a ribavirin injection batching device which comprises a main body tank, a cover plate is arranged at the upper end of the main body tank, a rubber sealing gasket is connected to the lower end of the cover plate through a pipeline, the rubber sealing gasket is arranged in the main body tank, a feeding port is formed in the cover plate and the rubber sealing gasket in a penetrating mode, and the feeding port is communicated with the interior of the main body tank. A flow guide assembly is arranged in the main body tank, a transmission bin is formed in the main body tank, a transmission assembly is arranged in the transmission bin and used in cooperation with the flow guide assembly, and a discharging port and an observation window are fixedly connected to the surface of the main body tank. By means of the design, a complete vertical stirring channel is formed, the solution is effectively mixed, it is ensured that the formula is uniform, and at the moment, the second flow guide fan synchronously runs to assist the solution above to be distributed to the bottom to be redistributed.

The invention discloses a method for simultaneously determining N-sodium laureth sarcosinate and phenol red residues in an injection based on a UPLC-MS / MS (Ultra Performance Liquid Chromatography-Mass Spectrometry / Mass Spectrometry) method. According to the method, on the basis of an ultra-high performance liquid chromatography-tandem triple quadrupole mass spectrometer, a 5mM ammonium acetate solution (containing 10% acetonitrile) is taken as a phase A, a 0.2% acetic acid acetonitrile solution is taken as a phase B, a Waters Acquity UPLCBEH C18 column is selected, ESI is taken as a mass spectrometry detection ion source, and the two process residues in the injection are accurately quantified at the same time in a negative ion scanning and multi-reaction monitoring mode. The method is simple in pretreatment, high in detection sensitivity and good in reproducibility, and can be used for corresponding injection process residue identification and quality control.

This invention belongs to the pharmaceutical field and discloses a rubitetidine pharmaceutical composition, its preparation method, and its application. The pharmaceutical composition includes rubitetidine, an organic acid, and additives, wherein: rubitetidine has crystal forms including crystal form C and / or crystal form D; the additives include a lyophilization protectant or a solution stabilizer; the lyophilization protectant is a saccharide compound and / or its derivative; and the solution stabilizer is an alcohol compound. This invention focuses on rubitetidine crystal form C and rubitetidine crystal form D, and prepares a lyophilized rubitetidine formulation by adding specific organic acids and lyophilization protectants. This formulation exhibits good solubility and stability. Furthermore, by adding specific organic acids and solution stabilizers, a rubitetidine injection solution with similarly good solubility and stability can be prepared without adding lyophilization protectants or using a lyophilization-free process, optimizing the process steps and solving the problems of long production cycles and cumbersome reconstitution operations associated with traditional products.

The invention relates to a dexamethasone sodium phosphate injection and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations. The preparation method comprises the following steps: 1, sequentially adding glycerol, edetate disodium and dexamethasone sodium phosphate into water for injection according to a weight ratio of (20-25): (0.08-0.12): (4-6), mixing and dissolving, and introducing nitrogen until the dissolved oxygen content is less than or equal to 1mg / L to obtain a liquid medicine 1; step 2, adding a pH regulator into the liquid medicine 1 to regulate the pH value to 7.0-8.5 to obtain liquid medicine 2; and step 3, filtering, filling and sealing the liquid medicine 2, and controlling the residual oxygen content to be less than or equal to 5% to obtain the dexamethasone sodium phosphate injection. Wherein the whole preparation process is protected by inert gas. According to the preparation method of the dexamethasone sodium phosphate injection provided by the invention, the prescription composition of an original drug does not need to be changed, and the prepared dexamethasone sodium phosphate injection can be stably stored at room temperature by adjusting a specific pH range, keeping filling of an inactive gas until the dissolved oxygen content is less than or equal to 1mg / L in the whole preparation process and controlling the residual oxygen content to be less than or equal to 5%.

The utility model relates to transfusion bottle technical field discloses a self -discharge formula glucose injection transfusion bottle bottle body, including bottle body and the pendant of fixed on bottle body, bottle body is by bottle body, bottle neck section and bottle mouth section is composed, the inner wall of bottle neck section is fixedly connected with the liquid lifting subassembly, the first envelope is equipped with in the bottle mouth section, the side wall of first envelope is fixedly connected with the support cover, one end of support cover and liquid lifting subassembly is through sliding arrangement. In the utility model, when only a small amount of glucose injection is left in the bottle body, the elasticity of the isolating sleeve makes the contraction sliding sleeve slide upward along the outer wall of the support cover, lifting the liquid level of the glucose injection in the bottle body, greatly reducing the residue of the glucose injection in the bottle body. By setting the protective cover, T-shaped column and the second through hole, the first envelope is protected and further fixed. The protective cover does not need to be removed when the infusion device needle is inserted.

The invention discloses a method for detecting anions in a phlegm-heat-clearing injection, the detection method comprises the following steps: a test solution and a reference solution are taken for detection, the phlegm-heat-clearing injection is composed of scutellaria baicalensis, bear gall powder, cornu gorais, honeysuckle, fructus forsythiae and propylene glycol; chromatographic conditions of the detection are as follows: an anion exchange chromatographic column is adopted, an eluent is an acid aqueous solution, an alkali aqueous solution and / or a buffer salt aqueous solution, the flow velocity is 0.1-2.0 ml / min, the column temperature is 20-40 DEG C, a detector is an electrical conductivity detector, the detection mode is suppression electrical conductivity detection, and the sample size is 10-40 [mu] l; and obtaining the content information of the anions in the phlegm-heat clearing injection according to the detection result. The method disclosed by the invention is simple, convenient, efficient and rapid, and provides a theoretical basis for the quality control of the phlegm-heat clearing injection and the deep research of a pharmacodynamic material basis by detecting the content of the anions.

Stable, injectable pharmaceutical compositions are provided, which are useful as ready-to-dilute (RTD) or ready-to-use (RTU) liquid injectable compositions comprising bendamustine or a pharmaceutically acceptable salt thereof, and which are suitable for intravenous administration. Preferably, solution formulations comprise (a) bendamustine, or pharmaceutically acceptable salts, solvates, or hydrates thereof, (b) at least one pharmaceutically acceptable non-aqueous solvent; (c) optionally, at least one pharmaceutically acceptable excipient, and (d) optionally, a pH adjuster, where the pharmaceutical composition is antioxidant-free, and formulated as a ready-to-dilute or ready-to-use liquid composition suitable for parenteral administration. The invention further relates to methods for manufacturing stable, antioxidant-free injectable solutions of bendamustine.

This invention discloses a carbetocin injection solution and its preparation process. The raw materials for the carbetocin injection solution include at least carbetocin, methionine, disodium edetate, an antibacterial agent, a pH adjuster, and a solvent. The pH of the carbetocin injection solution is 4.0-4.5. The concentration of carbetocin is 50 μg / ml-80 μg / ml, the concentration of methionine is 10 mg / ml-20 mg / ml, the concentration of disodium edetate is 5 mg / ml-10 mg / ml, and the concentration of the antibacterial agent is 2 mg / ml-3 mg / ml. By controlling the concentrations of carbetocin, methionine, disodium edetate, and the antibacterial agent, and simultaneously adjusting the pH of the injection solution to 4.0-4.5, this invention eliminates the need for nitrogen purging during the preparation process, thereby enabling the prepared carbetocin injection solution to exhibit high antioxidant properties and stability, allowing for long-term storage at room temperature.