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383 results about "Physiological saline" patented technology

Physiological saline. n. A sterile solution of sodium chloride that is isotonic to body fluids, used to maintain living tissue temporarily and as a solvent for parenterally administered drugs.

Direct in-scope suction system

The invention disclosed in this document presents a novel direct in-scope suction system designed for the retrieval of calculus fragments within the body. This system comprises two key components: a calculus fragments retrieval device and a pump unit. The calculus fragments retrieval device features a body with a single working channel that includes both an irrigation port and a suction port, which are connected to respective irrigation and suction pumps via elastomer-based rubber tubes. This setup allows for the controlled infusion of saline solution into the body lumens during lithotripsy procedures, ensuring clear visibility and fragment clearance. The retrieval device includes a trigger lever connected to a pincher tab. When the operator presses the trigger lever, the suction port is opened by releasing the pinched suction tube, increasing pressure inside the body.
Owner:BIORAD MEDISYS PTE LTD

Device and method for measuring cross sectional area of tendon

The invention belongs to the technical field of medical instrument evaluation, particularly relates to a tendon cross-sectional area measuring device and a tendon cross-sectional area measuring method, and provides the tendon cross-sectional area measuring device and the tendon cross-sectional area measuring method on the basis of a volumetric method and a die forming technology. The long and thin cylindrical measuring cylinder is used for containing normal saline, the pressure sensor is used for measuring the hydraulic pressure change caused by the fact that the tendon is immersed in the normal saline, then the liquid volume change is obtained, and the average cross sectional area of the tendon under the corresponding displacement is obtained based on the displacement of the tendon immersed in the liquid. Further, the minimum point of the tendon cross section area is accurately measured, and a reference is provided for a later tensile test.
Owner:SHANDONG INST OF MEDICAL DEVICES & DRUG PACKAGING INSPECTION

Use of exercise-induced sweat extract for the preparation of a medicament for the treatment, prevention or alleviation of depression, anxiety

PendingCN122376622AHigh dosesHealthy subjects
The application provides an application of a motion-induced sweat extract in preparation of a medicine for treating, relieving or preventing depression and / or anxiety, and belongs to the field of biological medicine. Specifically, sweat is induced by making a healthy subject perform aerobic exercise of a specific intensity (such as 60%-80% of maximum heart rate), the sweat is collected and eluted by physiological saline, centrifuged and filtered to obtain a biologically active sweat extract. The extract is analyzed by transcriptomics and reverse transcription method to predict the anti-depression potential, and it is proved by in-vivo animal experiments that the extract can significantly improve the anhedonia, behavioral despair and anxiety-like behavior of a depression model mouse, and the effect of a high dose is equivalent to that of a first-line drug fluoxetine. The preparation raw material provided by the application is natural and safe, the preparation process is simple and the cost is low, and a new, easy-to-promote alternative strategy is provided for the prevention and treatment of depression.
Owner:WUHAN SPORTS UNIV

A consumable delivery device

PendingCN122440965ACatheterGuide wires
The application discloses a kind of consumable conveying devices, comprising: guide wire conveying unit, guide wire is contained in guide wire coil and passes between the pair of guide wire guide wheels, with the rotation of guide wire guide wheel, guide wire is driven forward or backward to retreat;And catheter / stent conveying unit, catheter / stent is contained in catheter / stent coil and passes between the pair of catheter / stent guide wheels, with the rotation of catheter / stent guide wheel, catheter / stent is driven forward or backward to retreat;Wherein the proximal end of guide wire coil is provided with guide wire wetting section, at guide wire wetting section, the upper end side wall of guide wire coil is provided with drop opening, heparin or physiological saline is dropped through drop opening, to wet guide wire in guide wire coil.The application conveys guide wire, catheter / stent and other medical instruments by conveying device, improves the efficiency of guide wire, catheter or stent into human body, reduces the pollution in the preoperative preparation process of guide wire, catheter or stent, and then simplifies the operation of doctor.
Owner:J ROBOTICS MEDICAL LTD

Coronary sinus balloon counterpulsation catheter

PCT designated stageWO2026016841A1Blood pumpsIntravenous devicesCoronary sinusBalloon catheter
Provided in the present invention is a coronary sinus balloon counterpulsation catheter, comprising a catheter body and a balloon. The catheter body is provided with a first channel and a second channel that extend through the catheter body along the axial direction thereof. The first channel is eccentric to the catheter body. A cross-section of the second channel comprises a first contour line and a second contour line. The first contour line is at least a part of a first circle. The second contour line is at least a part of a second circle. The first contour line is closer to the first channel than the second contour line, and concave sides of the first contour line and the second contour line both face the first channel. The width of the second channel satisfies a predetermined relationship. The balloon is in sealed connection with a distal outer peripheral surface of the catheter body and is in communication with the second channel. The arrangement mode of the first channel and the second channel enables a filling liquid flowing in the second channel to have a relatively low resistance and a relatively high flow rate. In this way, the coronary sinus balloon counterpulsation catheter can use a liquid such as normal saline instead of a gas as a filling medium, thereby avoiding the occurrence of air embolism caused by balloon rupture and improving the safety of use.
Owner:SHANGHAI MICROPORT RHYTHM MEDTECH CO LTD

Hydrogen-containing normal saline high-tightness vacuum hydrogen locking packaging preparation method

The invention provides a hydrogen-containing normal saline high-tightness vacuum hydrogen locking packaging preparation method, which belongs to the technical field of medical liquid packaging, and comprises the following steps: pressurizing prepared hydrogen by using a hydrogen booster pump so as to store high-pressure hydrogen; high-pressure hydrogen is rapidly filled into the high-pressure pressure tank to permeate into the single bottle of normal saline, the residual hydrogen is recycled for cyclic utilization, bottled hydrogen-containing normal saline is obtained and put into a composite aluminum foil bag to be subjected to vacuumizing treatment and heat sealing treatment, a high-sealing-performance vacuum hydrogen locking aluminum foil bag packaging piece is obtained, and a finished product is detected. And quickly freezing qualified products, and refrigerating and storing the qualified products to complete hydrogen locking preparation. High-pressure hydrogen permeates into a single bottle of normal saline, the traditional hydrogen permeation period of several hours is shortened to dozens of seconds, the composite aluminum foil bag is vacuumized and subjected to heat sealing treatment, hydrogen escape is effectively inhibited, the quality guarantee effect is remarkable, the process operation is simple, the hydrogen is recycled, the cost is saved, and the method is suitable for mass production.
Owner:左国云

Extraction and purification method of hemin

ActiveCN121537395AOrganic chemistrySodium acetateHemin
The invention relates to the technical field of heme purification, in particular to a heme extraction and purification method. Comprising the following steps: taking fresh animal blood, centrifugally collecting lower red blood cell precipitate, adding normal saline, uniformly mixing and washing; adding an ethanol solution with the concentration of 1-10%, uniformly mixing, and ultrasonically crushing for 15-60 seconds under the power of 300-800W to obtain erythrocyte crushing liquid; adding an acidic acetone solution into the erythrocyte crushing liquid, uniformly mixing, extracting at normal temperature, centrifuging, and collecting supernate to obtain an acidic acetone extracting solution; slowly adding a NaOH solution to adjust the pH value; adding sodium acetate, stirring, standing, taking precipitate, washing and drying to obtain a crude product; filling a silica gel column; loading the crude product, eluting with an eluent, and collecting an elution component containing a target product; the eluent comprises dichloromethane, methanol and formic acid; and removing the mobile phase in the elution component. The method has the advantages of simple process, low cost, environmental friendliness and capability of obtaining a high-purity product.
Owner:JILIN AGRICULTURAL UNIV

Transcervical access systems for intrauterine fluid exchange, e.g., placement of hydrogels formed in situ.

PendingJP2026123216ACol uterinEndoluminal surgery
This invention provides a transcervical access system for moving fluids transcervically. [Solution] The transcervical access system 100 is effective in transferring a wide range of fluids into the uterine cavity, including the delivery of a hydrogel precursor, saline solution, and imaging fluid. The transcervical access system 100 is also effective in removing fluids, such as residual bodily fluids, residual fluids from procedures, or tissue from the uterine cavity. The transcervical access system 100 includes a flow limiter, such as an outflow limiter 106 and / or a cervical plug. A method of using the transcervical access system 100 involves using the transcervical access system 100 to transcervically access the uterine cavity and to install the hydrogel. The transcervical access system 100 and related methods are useful in preventing adhesions after intrauterine procedures by providing a biodegradable hydrogel within the uterine cavity, including the cervix.
Owner:PRAMAND LLC

Small-cavity surgical robot with anti-blocking mechanism

The invention provides a small-cavity surgical robot with an anti-blocking mechanism, and relates to the technical field of surgical robotics.The small-cavity surgical robot comprises a mechanical arm, an operation platform is rotationally installed on the mechanical arm, an operation instrument used for conducting an operation on a patient is arranged on the operation platform, and a fixing frame is fixedly installed on the operation platform; a circular space between the inner pipe and the outer pipe is divided into two independent areas, the two independent areas are matched with the two connecting pipelines on the outer pipe and the connected micro peristaltic pump, and therefore the inner pipe and the outer pipe can be separated into two independent areas. By means of the design, normal saline and a low-concentration heparin solution can be conveyed respectively, the washing requirement in a conventional operation is met, anticoagulation treatment can be provided for an operation scene with the high blood coagulation risk, the application range of the surgical robot is greatly widened, surgical operation is more targeted and flexible, and the surgical robot is suitable for being popularized and used. And individual differences of different patients can be effectively handled.
Owner:SUN YAT SEN UNIV

Contrast agent filtering device for coronary artery surgery and use method of contrast agent filtering device

The invention discloses a contrast agent filtering device for coronary surgery and a using method thereof, the device is integrally in a plastic bag shape and comprises a filtering bag body, the bottom of the filtering bag body is provided with a transfusion connector and a blood transfusion connector which are provided with sealing covers, and an inner opening is sleeved with a filter screen support with a filter screen; the filter bag body is divided into a filter area and an adsorption particle storage area through a middle seal, a flushing connector and a hanging hole are arranged at the top, and the filter bag body can be matched with a vibration disc for use. The use method comprises the steps that blood containing a contrast agent is extracted and input into the filtering area, the middle seal is opened through pressing, the blood makes full contact with the adsorption particles through vibration or manual extrusion so as to adsorb the contrast agent, then the filtered blood is infused back, and residual plasma can be infused back after being diluted with normal saline. The device is simple in structure, low in cost and easy and convenient to operate, the filtering effect is improved by 30% compared with the prior art, the adsorption rate reaches 75%-85%, contrast agents in blood can be effectively removed, damage to the kidney of a patient is reduced, and the device is particularly suitable for blood treatment of the patient after coronary angiography.
Owner:BEIJING ZKSK TECH

A fabric yellowing agent and a method of fabric yellowing

The application discloses a fabric yellowing reagent and a fabric yellowing method, and relates to the technical field of daily chemical products. 5 The fabric yellowing reagent comprises 1-3% of histidine solution and a bacterial suspension with a bacterial concentration of 1*10 5 CFU / mL-9*10 The bacteria are a mixture of one or more of Staphylococcus epidermidis and Micrococcus luteus; the solvent of the histidine solution is normal saline containing 0.15-1% of trypsin peptone; and the solvent of the bacterial suspension is normal saline containing 0.1-0.2% of trypsin soybean peptone liquid culture medium. The fabric yellowing reagent can be used for simulating fabric yellowing, and has good operability, reproducibility and data reliability.
Owner:GUANGZHOU LIBY ENTERPRISE GROUP CO LTD

Anaerobic denitrifying bacterial agent as well as preparation method and application thereof

The invention discloses an anaerobic denitrifying bacterial agent as well as a preparation method and application thereof, and belongs to the technical field of water environment treatment. The anaerobic denitrifying bacterium agent is prepared from the following components in parts by weight: 15 to 30 parts of sterile water, 15 to 60 parts of normal saline, 5 to 10 parts of micro-capsule embedded anaerobic denitrifying bacteria, 5 to 20 parts of a porous composite modified carrier, 10 to 30 parts of a carbon source, 4 to 7 parts of nutrient elements, 2.5 to 4 parts of a buffering agent and 1 to 5 parts of a stabilizer, the micro-capsule embedded anaerobic denitrifying bacteria are obtained by embedding anaerobic denitrifying bacteria with an alginic acid gel solution and a calcium chloride solution; the porous composite modified carrier is obtained by crosslinking modified nano iron oxide, modified nano titanium dioxide, a functional polymer solution and glutaraldehyde. The anaerobic denitrifying bacterial agent provided by the invention can effectively improve the efficiency of treating nitrogen pollution of a water body.
Owner:CHENGDU XINBOAO OIL & GAS ENG TECH SERVICE CO LTD

An endoscopic spine surgery patch

ActiveCN224387531Uavoid running aroundavoid runningSuture equipmentsInternal osteosythesisSpinal columnEndoscopic Procedure
The utility model discloses a kind of endoscope surgery pasting film, it is related to medical supplies technical field, including first film, second film, water baffle and liquid collecting and guiding bag.The bottom surface of first film is used to paste on skin.Second film is located on the top surface of first film, and the accommodating cavity that is formed with upward protrusion between second film and first film.Water baffle is located in accommodating cavity, and the region formed by surrounding water baffle is used to accommodate liquid.Liquid collecting and guiding bag is connected with one side of second film, and the bag opening of liquid collecting and guiding bag is towards the opening of water baffle, so that the liquid in the region formed by surrounding water baffle can flow into liquid collecting and guiding bag.In the process of operation by doctor, water baffle can be resisted by second film with physiological saline and patient's blood and other liquids, that is, water baffle plays a blocking role to liquid, so that liquid in the process of operation all stays in the region formed by surrounding water baffle, avoid the pollution of the surrounding environment of operation area.
Owner:THE FIFTH AFFILIATED HOSPITAL SUN YAT SEN UNIV

Disposable automatic fascia pressure measuring instrument

The invention relates to the technical field of fascia pressure measuring instruments, in particular to a disposable automatic fascia pressure measuring instrument which comprises a measuring instrument shell, a control mechanism is fixedly connected to the bottom end of the interior of the measuring instrument shell, a suction mechanism is fixedly connected to one side of the interior of the measuring instrument shell, and an injection mechanism is installed on the other side of the interior of the measuring instrument shell. When air in the fascia chamber is evacuated, in order to inject normal saline and monitor the pressure in the fascia chamber, a first gear is driven to rotate through rotation of a first motor, so that the first gear is conveniently driven to rotate in the rotating process, and the normal saline is injected into the fascia chamber; and a first gear rotates to be meshed with a first gear rack, so that a first push rod at one end of the first gear rack is driven to be pulled, the first push rod drives a first piston to be pulled in a suction cylinder, and the suction cylinder pumps out air in a fascia chamber through a first conveying pipe.
Owner:SHENZHEN NANSHAN DISTRICT PEOPLES HOSPITAL

Syringe with priming indicator

Syringes are provided that include a syringe body defining a syringe cavity, a syringe port, and an indicator window, a medication plunger disposed within the syringe cavity and defining a medication chamber in the syringe cavity, a priming indicator comprising a first indicator portion and a second indicator portion, the priming indicator coupled to a plunger shaft of the medication plunger, wherein the priming indicator presents the first indicator portion through the indicator window in an unprimed position and presents the second indicator portion through the indicator window in a primed position, and a saline plunger disposed on the plunger shaft, the saline plunger disposed within the syringe cavity and defining a saline chamber in the syringe cavity. Medication delivery systems and methods to deliver medication via medication delivery systems are also provided.
Owner:CAREFUSION 303 INC

Preparation method of intestinal canal filling temperature-sensitive gel injection for gastrointestinal anastomosis guided by ultrasonic endoscope

PendingCN121754738ASurgeryPyrrolidinonesBiology
The invention discloses a preparation method of an intestinal canal filling temperature-sensitive gel injection for gastrointestinal anastomosis guided by an ultrasonic endoscope, and belongs to the technical field of regenerative medicine. According to the specific method, poloxamer, chitosan, polycarbophil, polyvinylpyrrolidone, iohexol and methylene blue are utilized to construct the novel intestinal canal filling temperature-sensitive gel injection. The injection can be injected into the anastomotic intestinal segment of the small intestine by using a conventional nasobiliary drainage tube which is clinically used at present, and the injection becomes viscous immediately under the action of the pH value of the small intestine after injection, so that the injection is inhibited from spreading all around. Meanwhile, the injection is quickly converted into high-strength hydrogel under the action of body temperature, and the hydrogel is adhered to small intestine mucosa to inhibit gel sliding. Therefore, the injection can form a section of gel on a target small intestine section, local immobilization filling and supporting of the target small intestine section are achieved, development can be achieved, the operation difficulty of intestinal tube puncture and stent placement in gastrointestinal anastomosis guided by an ultrasonic endoscope can be greatly reduced, the operation efficiency and the success rate are improved, and the operation cost is reduced. The dosage is less than that of normal saline which is conventionally used clinically, and the effect is better. Moreover, the gel temperature can be reduced by injecting low-temperature normal saline after the operation, so that the gel is thoroughly dissolved into a solution and discharged out of the body, and the phenomenon that the gel remains in the intestinal canal after the operation to cause obstruction is avoided. Therefore, the novel intestinal canal filling temperature-sensitive gel injection has very important clinical practical application value for gastrointestinal anastomosis guided by an ultrasonic endoscope.
Owner:SHENGJING HOSPITAL OF CHINA MEDICAL UNIVERSITY

Aspirator for cleaning secretions of ears and noses

The utility model provides an aspirator for ear and nose secretion cleaning, which comprises a cabinet, an operating table is fixedly mounted at the top of the cabinet, a first guide cavity and a second guide cavity are respectively arranged in the operating table, a guide chamber and a collection chamber are respectively arranged in the cabinet, and the first guide cavity and the second guide cavity are communicated with each other. A saline water barrel and a collecting assembly are arranged in the collecting chamber, a flow dividing assembly is fixedly installed in the guiding and conveying chamber, the output end of the flow dividing assembly penetrates through the first guiding and conveying cavity and is provided with an injection head in a butt joint mode, and the input end of the flow dividing assembly is connected with the saline water barrel; the input end of the collecting assembly is in butt joint with a recoil assembly. According to the utility model, normal saline in the saline water barrel is extracted through the back flushing assembly, so that the suction operation can be realized, meanwhile, the saline water can be fed into the suction pipeline, not only can sucked foreign matters be discharged in an auxiliary manner, but also the interior of the suction pipe can be continuously flushed, and the inner wall of the suction pipe is prevented from being bonded and blocked.
Owner:THE SECOND AFFILIATED HOSPITAL OF ANHUI MEDICAL UNIV

Enteric cavity inner segment filling controllable device for T stage before colon cancer operation

The invention relates to the technical field of medical instruments, in particular to an enteric cavity segment filling controllable device for colon cancer preoperative T staging, which comprises a central mandrel, a flexible head end cap is arranged at the foremost end of the central mandrel, and a near-end balloon inflating pipeline, a far-end balloon inflating pipeline and a main pipeline which are mutually independent are arranged in the central mandrel; the near-end balloon is arranged on the central mandrel in a sleeving manner and is communicated with the near-end balloon inflating pipeline; the far-end balloon is arranged on the central mandrel in a sleeving manner, is positioned on the far side of the near-end balloon and is communicated with the far-end balloon inflating pipeline; at least two main pipeline lateral holes are formed in the tube wall of the central mandrel between the near-end balloon and the far-end balloon, are communicated with the main pipeline and are used for injecting a contrast agent or normal saline into the closed enteric cavity section between the two balloons. The near-end balloon and the far-end balloon are synchronously filled at the two ends of a target intestinal segment to form a closed segment, and a contrast agent is uniformly injected through lateral opening, so that the intestinal wall is fully expanded and does not collapse, and the display definition of the five-layer structure of the intestinal wall is remarkably improved.
Owner:AFFILIATED ZHONGSHAN HOSPITAL OF DALIAN UNIV

Hematocele-preventing drainage device for neurosurgery department

The invention discloses an anti-hematocele drainage device for the neurosurgery department in the technical field of medical instruments, and the anti-hematocele drainage device for the neurosurgery department comprises a fixing box, a drainage assembly, a cleaning liquid conveying assembly, a dredging assembly and a rotary adjusting assembly.The drainage device is characterized in that drainage is started through a drainage channel located on the lower portion, and the drainage channel located on the upper portion is closed and connected with a flushing branch pipe; normal saline is conveyed to the flushing branch pipe through the cleaning liquid conveying assembly, the interior of the drainage channel located above is flushed, the dredging assembly is driven to dredge and smash tissue debris flushed down from drainage objects and waste liquid, blockage is prevented, and after dredging is conducted for a period of time, the rotary adjusting assembly is driven to drive the movable drainage pipe to rotate, so that the drainage effect is improved. The positions of the two drainage channels are adjusted, the interior of the other channel can be flushed while one channel is used for drainage, the positions of the two drainage channels are rotated and switched after flushing, clogged drainage objects during drainage are flushed out while continuous drainage operation is kept, and the problem that the drainage efficiency is affected due to blockage can be effectively prevented.
Owner:JILIN UNIV FIRST HOSPITAL

Color-changeable pressure-measuring urinary catheterization device

ActiveCN224141271USensorsUrological function evaluationUrethral catheterizationUrethra
The utility model relates to a variable-color pressure-measuring catheterization device, and relates to the technical field of pressure-measuring catheterization devices.The variable-color pressure-measuring catheterization device comprises a catheter and a pressure-measuring tube, one end of the catheter is connected with a urine bag, and a first communicating valve is arranged at the end, close to the urine bag, of the catheter; the end, close to the urethra, of the urethral catheter is communicated with a first connecting pipe and a second connecting pipe, the first connecting pipe is used for inputting normal saline into the urethral catheter, the second connecting pipe is used for being communicated with the pressure measuring pipe, the first connecting pipe is provided with a second communicating valve, and the second connecting pipe is provided with a second communicating valve. A third communication valve is arranged at the end, away from the end connected with the second connecting pipe, of the pressure measuring pipe, and a connecting assembly connected with the pressure measuring pipe is arranged on the second connecting pipe. The pressure measuring device has the advantages that the pressure of a patient can be conveniently measured, the discomfort of the patient caused by the pressure measuring device is reduced, and meanwhile the pressure measuring device can be conveniently detached.
Owner:MEIOU WEIKE MEDICAL WUHAN CO LTD

Streptococcus oral cavity ZRSOR-5 as well as related products, method and application thereof

PendingCN122012326ABacteriaMicroorganism based processesMicroorganismLung Inflammations
The invention provides oral streptococcus ZRSOR-5 as well as a related product, a method and application thereof. The preservation number of the streptococcus oral cavity ZRSOR-5 provided by the invention in the Guangdong Microbial Culture Collection Center is GDMCC No: 65352, and the preservation number of the streptococcus oral cavity ZRSOR-5 provided by the invention is CGMCC No: 65352. Experiments prove that the SOR preparation is prepared by diluting the SOR preparation with normal saline and inhaling the SOR preparation into mice in advance, so that the survival rate of influenza virus infected mice can be remarkably increased, and lung inflammation and virus load can be reduced. When the ZRSOR-5 preparation provided by the invention is used in advance, pneumonia caused by influenza viruses can be resisted.
Owner:CHINA JAPAN FRIENDSHIP HOSPITAL

A method for preparing CCR2+ gamma delta T cells with anti-tumor activity and migration ability

The application discloses a preparation method of CCR2+ gamma delta T cells with anti-tumor activity and migration ability, and belongs to the technical field of cells; the method comprises the following steps: step (1), PBMC of peripheral blood of a healthy person is extracted, inoculated into complete culture medium, and added with zoledronic acid, IL-15 and metformin, and then is cultured in a T25 culture bottle; step (2), complete culture medium is supplemented, the cell concentration is adjusted, and then the cells are transferred into a T75 culture bottle for culture; step (3), complete culture medium is supplemented, the cell concentration is adjusted, glucocorticoid and nicotinamide are added, and then the cells are transferred into a T150 culture bottle for culture; step (4), cells are collected at D6, rinsed with normal saline, resuspended with complete culture medium, the cell concentration is adjusted, and then the cells are inoculated into a T300 culture bottle for culture; and step (5), complete culture medium is supplemented every two days from D8 to D16, the cell concentration is maintained, and then the cells are harvested at D16 to obtain CCR2+ gamma delta T cells.
Owner:BEIJING WEICHUANG BOJING BIOTECHNOLOGY CO LTD

A cefminox sodium preparation for injection and a method for preparing the same

ActiveCN117899014BSodium lactateVITAMIN B12 INJECTION
This invention provides an injectable cefminox sodium preparation and its preparation method, belonging to the field of pharmaceutical preparation technology. The preparation, by weight, comprises: 1 part of refined cefminox sodium, 0.5 parts of sodium lactate Ringer's solution, 0.2 parts of vitamin B12 injection, 0.1-0.3 parts of a modified composite antioxidant, and 3 parts of physiological saline. The preparation method of the modified composite antioxidant is as follows: S1, add 1 part by weight of poloxamer to 20 parts by weight of distilled water and stir for 6-8 minutes to obtain a solution; S2, after passing 1 part by weight of natural vitamin C through a 100-mesh sieve, mix it into the solution obtained in S1, and sonicate for 10-15 minutes to obtain a vitamin C solution; S3, mix 0.5 parts by weight of vitamin D into the vitamin C solution obtained in S2, and sonicate for 15-20 minutes to obtain the modified composite antioxidant. The formulation of this invention exhibits excellent stability and stable content of cefminox sodium when exposed to environments of 35℃±2℃, 65%±5%RH and natural light, ensuring the safety and reliability of medication.
Owner:上海欣峰制药有限公司

Treatment process of hydrophilic implant

The invention relates to the technical field of metal surface treatment, in particular to a treatment process of a hydrophilic implant. According to the process, the implant is sequentially subjected to sand blasting and acid etching, compound acid solution activation, gradient alkaline neutralization, multi-stage ultrasonic cleaning, low-temperature plasma modification, nitrogen protection ultraviolet radiation and normal saline sealing storage treatment. Through a multi-step synergistic effect, a stable hydrophilic micro-nano structure is constructed on the surface of the implant, a large number of Ti-OH hydrophilic groups are formed, carbon and hydrogen atom adsorption is effectively isolated, and the problems that the hydrophilicity of an existing implant is prone to loss, osteoblast climbing is difficult, and the healing period is long are solved. The implant treated by the process is durable and stable in hydrophilicity, the healing period after implantation is shortened to about one month, the planting survival rate is remarkably increased, the process is green and safe, and industrial production can be realized.
Owner:CHANGZHOU RUITIKE MEDICAL INSTR CO LTD

Sulfonated gelatin microspheres and preparation method thereof

PendingCN121422287ASurgical adhesivesGelatin microspheresFreeze-drying
The invention relates to the technical field of interventional medicine, in particular to sulfonated gelatin microspheres and a preparation method thereof. The preparation method comprises the following steps: adding gelatin into a buffer solution, heating, stirring and dissolving to obtain a water phase, adding a dispersing agent into an oil phase matrix solution, stirring to obtain an oil phase, transferring the water phase into the oil phase, stirring, and cooling to obtain gel microspheres; the preparation method comprises the following steps: primarily cleaning gel microspheres, putting the gel microspheres into a freezing medium for freeze drying, then adding the freeze-dried gel microspheres into normal saline, adding a cross-linking agent for a cross-linking reaction, then adding a sulfonation reagent, a catalyst and an initiator for a sulfonation reaction, and finally, carrying out secondary cleaning on the microspheres after the sulfonation reaction is finished, so as to obtain the hydrogel. The sulfonated gelatin microspheres are obtained. According to the preparation method, the cross-linked microspheres are firstly prepared, then the cross-linked microspheres are subjected to sulfonation treatment, the reaction conditions are mild, the process is simple, amplified production is easier to perform, the microspheres (45 [mu] m) with very small particle sizes can be obtained, and the adhesion condition is avoided.
Owner:JIANGSU MEDNOVO MEDICAL GRP CO LTD

Sputum suction tube flushing device

ActiveCN224222237ULimit rotationConvenient to observe the injection statusHollow article cleaningSurgeryBiomedical engineering
The utility model provides a sputum suction tube flushing device, and belongs to the technical field of sputum suction tubes. The sputum suction tube flushing device comprises a flushing assembly and an adjusting assembly, the flushing assembly comprises a bottom plate, a driving part, a sliding rod, a piston, an injection tube, a liquid suction tube, a flushing tube and a one-way valve, the driving part is arranged at the bottom of the bottom plate, and the adjusting assembly comprises an elastic part, a sliding ring and a positioning rod. By arranging the bottom plate, the driving piece, the sliding rod, the piston, the injection pipe, the liquid suction pipe, the flushing pipe and the one-way valve, the one-way valve is adopted to control the liquid suction pipe and the flushing pipe to flow liquid in one way, the situation that a sputum suction pipe needs to be disassembled to repeatedly suck and supplement normal saline for continuous flushing can be avoided, steps are reduced, and efficiency is improved; by arranging the elastic piece, the sliding ring and the positioning rod, the sliding ring can be rotated to drive the injection tube to rotate to adjust the positions of the liquid suction tube and the flushing tube, the device adapts to adjustment of the positions of different patients or sputum suction tubes, and practicability is improved.
Owner:SUZHOU JINSHENG PLASTIC CO LTD

Inlet marine fish pathogenic parasite sampling and detecting device

The invention belongs to the technical field of parasite sampling, particularly relates to an imported marine fish pathogenic parasite sampling and detecting device, and provides the following scheme aiming at the problems of low manual sampling efficiency, inaccurate positioning and easy sample damage in existing marine fish parasite quarantine. Comprising a sampling base, a movable supporting plate, a sampling area identification assembly, a sampling pipe and a negative pressure separation assembly. The sampling area identification assembly can losslessly and accurately position a suspected parasite infection area in a fish body. The sampling pipe is provided with an annular gas guide cavity and an annular liquid guide cavity, sterile gas and normal saline can be sprayed cooperatively, and minimally invasive and efficient stripping and recycling of insect bodies are achieved. The negative pressure separation assembly adopts a double-chamber design, a micro-filtration membrane is arranged in the negative pressure separation assembly, a sample can be shunted and independently treated in single operation, and a negative pressure liquid extraction pipe of the negative pressure separation assembly has an automatic valve function of negative pressure ventilation and normal pressure closing, so that subsequent in-situ fixation is facilitated. According to the invention, the whole process automation from precise minimally invasive sampling to automatic separation and fixation is realized.
Owner:CHANGCHUN CUSTOMS TECH CENT

Disposable electric pressurizing flushing and sucking pipe

A disposable electric pressurizing flushing and sucking pipe comprises a handle and a flushing and sucking pipe, the flushing and sucking pipe is fixedly mounted in one end of the handle, and the other end of the handle is connected with a normal saline connector and a waste liquid and negative pressure connector, and is characterized in that an electric pump and a lithium battery for supplying power to the electric pump are mounted in the handle; the inlet end of the electric pump is communicated with the normal saline connector through a first flushing connecting pipe, the outlet end of the electric pump is communicated with one way of the four-way connector through a second flushing connecting pipe, and the other three way of the four-way connector is connected with one end of the second suction connecting pipe, one end of the flushing suction pipe and one end of the anti-blocking flushing device. The other end of the second suction connecting pipe is communicated with the waste liquid and negative pressure connecting port, and a flow control valve is installed on the second suction connecting pipe and / or the second flushing connecting pipe. The device is simple in structure and convenient to manufacture and use, and the problem of insufficient flushing pressure is fundamentally solved.
Owner:HAIZE INST FOR APPLIED MEDICAL RES (WUXI) LTD

Scalpel facilitating waste discharge

The invention discloses a scalpel facilitating waste discharge, and relates to the field of medical instruments. The scalpel facilitating waste discharge comprises a scalpel holder, an outer scalpel assembly and an inner scalpel assembly. The outer cutter assembly comprises an outer cutter pipe, an inner cavity, a waste containing opening, a waste discharging opening and a water spraying module. The inner knife assembly comprises an inner knife tube, a driving module, a first communicating port and a second communicating port; the inner cutter pipe can shield the waste containing opening or be separated from the waste containing opening in the sliding stroke of the inner cutter pipe, and when the inner cutter pipe shields the waste containing opening, the second communicating opening communicates with the waste discharging opening. According to the scalpel, cut tissue chips can be directly discharged from the waste discharge port, the whole scalpel does not need to be taken out, the operation efficiency is improved, and secondary injury to a patient can be prevented; meanwhile, before the scalpel extends into the body of a patient, air in the inner cavity can be emptied through normal saline sprayed out of the water spraying module, and air blockage caused by the fact that the air enters the ventricle is effectively prevented.
Owner:SUZHOU SANSHENG EVERYTHING MEDICAL TECH CO LTD