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999 results about "Physiological saline" patented technology

Physiological saline. n. A sterile solution of sodium chloride that is isotonic to body fluids, used to maintain living tissue temporarily and as a solvent for parenterally administered drugs.

Portable wound surface protection brace and application method thereof

The invention discloses a portable wound surface protection brace and an application method thereof, and belongs to the technical field of medical instruments. The brace is of a cylindrical structure, is made of EVA materials, has flexibility, non-toxic characteristics and good supporting performance and is externally wrapped with cotton cloth and provided with ventilation through holes, high-density cotton strips are fixed to the two ends of the inner wall to form a hollow structure, and the circumference of the outer wall can be adjusted through at least three sets of bandages with hook-and-loop fasteners. And an antibacterial coating is added, so that clinical application is expanded. During application, a wound surface is subjected to liquid extraction and hydrogen peroxide cleaning in the earlier stage and then covered with insulin mixed normal saline gauze, and the dressing is prevented from making contact with clothes in cooperation with a brace; and smearing mupirocin ointment in the later stage and performing infrared irradiation, and continuously using the brace to keep the wound dry and zero contact. The brace can be repeatedly used, can adapt to various wound types and patient body types, effectively solves the problems of wound adhesion and friction in traditional nursing, creates a high-oxygen healing environment, remarkably shortens wound healing time, relieves pain of patients and improves life quality, and has good clinical application and popularization value.
Owner:PSYCHIATRIC HOSPITAL OF TUJIA & MIAO AUTONOMOUS PREFECTURE IN XIANGXI

Ureter structure with air bag

The utility model discloses a ureter structure with an air bag, and aims to solve the problems that 0.5 mL of normal saline needs to be injected into the air bag to jack up the air bag to enable the surface of the air bag to be smooth after the normal saline is pumped out when a ureter is pulled out in the prior art, the pain of a patient is prevented from being increased due to the fact that wrinkles of the air bag rub the urethral wall, and the workload is increased due to the increase of operation steps of nurses. And the catheter pulling speed is reduced. The urinary catheter comprises a urinary catheter body, a hose connector is mounted at the left end of the urinary catheter body, an air groove is formed in the outer surface of the urinary catheter body, a positioning air bag is fixedly connected to the inner wall of the air groove, an air channel is formed in the urinary catheter body and communicated with the air groove, and an air bag connector is fixedly connected to the outer surface of the urinary catheter body. Through the design, normal saline in the positioning air bag is quantitatively retained to support the positioning air bag so as to prevent the positioning air bag from wrinkling, the normal saline does not need to be injected into the positioning air bag for the second time, and the workload of medical staff is reduced.
Owner:GUANGZHOU ORTHOPEDIC HOSPITAL

Combined bioprosthetic valve material anti-calcification method and bioprosthetic valve material

The invention relates to the field of biomedical materials, and particularly discloses a combined biovalve material anti-calcification method and a biovalve material. A combined bioprosthetic valve material anti-calcification method comprises the following steps: taking an animal-derived biological material, cleaning, removing adipose tissue, cutting a precordial region part to obtain a pericardium material, and storing the pericardium material in ice normal saline for later use; mixing the pericardium material and the decellularized treatment fluid A, oscillating and cleaning; adding the pericardium material into the decellularized treatment solution B, oscillating and cleaning; carrying out crosslinking treatment by utilizing a glutaraldehyde pericardium material; adding the crosslinked pericardium material into a reducing agent solution, oscillating and cleaning; the method comprises the following steps: putting a pericardium material into a glycerol-ethanol mixed solution or a glycerol-isopropanol mixed solution, and soaking for more than 24 hours; according to the anti-calcification method, on the basis that the mechanical property of the valve material is effectively maintained, the anti-calcification performance is improved, and the durability of the valve material is improved.
Owner:QINGDAO GUOKE XINJIAN TECHNOLOGY CO LTD

Subperitoneal hepatic vein blood flow blocking device

InactiveCN120227101AOcculdersVeinSaline injection
The invention relates to the technical field of medical treatment, and discloses an intraperitoneal hepatic vein blood flow blocking device which comprises a drainage tension-brace mechanism, a hepatic vein blocking mechanism is arranged on the surface of the drainage tension-brace mechanism, a catheter recycling mechanism is arranged on the surface of the hepatic vein blocking mechanism, a hydraulic measuring mechanism is arranged at one end of the catheter recycling mechanism, and the hydraulic measuring mechanism is connected with the drainage tension-brace mechanism. And a normal saline injection mechanism is arranged at one end of the hydraulic measuring mechanism. According to the intraperitoneal hepatic vein blood flow blocking device, through the arrangement of the drainage pulling and supporting mechanism, the hepatic vein blocking mechanism, the catheter recycling mechanism, the hydraulic measuring mechanism and the normal saline pushing and injecting mechanism, the hepatic vein can be directly blocked through expansion of the hepatic vein blocking mechanism in the using process, and meanwhile it is guaranteed that the inferior vena cava blood flow can flow through a circulation cavity; therefore, smooth return blood circulation of the inferior vena cava is guaranteed.
Owner:SHANGHAI TENTH PEOPLES HOSPITAL

Cervical image classification method and system based on wavelet transform multi-modal fusion

The invention discloses a cervical image classification method and system based on wavelet transform multi-modal fusion, and the method comprises the steps: 1) constructing a multi-branch feature coding network, and respectively processing a cervical OCT image, a colposcope normal saline image, an iodine coating image and an acetic acid white image; 2) introducing wavelet transform to perform frequency domain decomposition on the multi-modal image, obtaining high-frequency and low-frequency components and designing a cross-frequency interaction mechanism to more effectively capture the structure and detail information of the image, and extracting each modal feature through a ResNet-18 backbone network; 3) designing a feature fusion module, performing channel stacking on the three colposcope features, compressing the three colposcope features, and cascading the three colposcope features with the OCT features to form fusion features; (4) feature dimension reduction is achieved through double full connection layers, a weighted voting multi-mode decision classification strategy is adopted, a five-fold cross validation strategy is adopted, and a weighted cross entropy loss function is combined to solve the problem of data imbalance, and (5) finally Softmax classification is carried out.
Owner:HUAZHONG NORMAL UNIV

Angiography injection device for enhancing nuclear magnetic resonance

The invention relates to the related technical field of medical instruments, in particular to a contrast injection device for enhancing nuclear magnetic resonance, which comprises a base, a mounting shell arranged at the upper part of the base, a first barrel arranged at the left upper part in the mounting shell, a second barrel arranged at the right upper part in the mounting shell, and a mixing barrel arranged in the middle of the upper part of the mounting shell, a first piston rod is arranged in the first barrel, a second piston rod is arranged in the second barrel, communicating pipes are respectively communicated between the first barrel and the mixing barrel and between the second barrel and the mixing barrel, a one-way water inlet pipe is arranged at the top of the barrel, and the one-way water inlet pipe is communicated with an external liquid storage tank. By rotating the adjusting screw rod, the adjusting screw rod drives the first wedge-shaped block to move to the position of the needed dosage, then the rodless air cylinder controls the extrusion plate to move upwards, and after the extrusion plate moves upwards and makes contact with the plate body, the piston rods move upwards to inject the contrast agent and normal saline of the corresponding dosage into the mixing barrel to be mixed.
Owner:JIANGXI BAOERAN BIOLOGICAL MEDICAL TECH CO LTD

Heparinized gelatin / sodium alginate pancreas islet packaging material with anti-fibrosis function as well as preparation method and application of heparinized gelatin / sodium alginate pancreas islet packaging material

The invention relates to a heparinized gelatin / sodium alginate pancreas islet packaging material with an anti-fibrosis function as well as a preparation method and application of the heparinized gelatin / sodium alginate pancreas islet packaging material. The preparation method comprises the following steps: adding gelatin into normal saline, soaking, performing autoclaved sterilization to obtain a gelatin solution, then adding epsilon-polylysine hydrochloride into the gelatin solution, and finally adding glutamine transaminase for reaction to obtain an epsilon-polylysine grafted gelatin solution; adding heparin into the solution, and reacting to obtain a heparinized gelatin solution; adding sodium alginate and glutamine transaminase, reacting, diluting, preparing hydrogel microspheres by adopting an electrostatic spraying method, and cross-linking to obtain the hydrogel microspheres. According to the invention, heparin molecules are incorporated into a pancreas islet packaging system, so that fibrosis at the periphery of the microspheres can be relieved, the pancreas islet cells are packaged by using the pancreas islet packaging material to prepare the biological artificial pancreas, the pancreas islet cell proliferation and insulin secretion can be promoted, and the pancreas islet packaging material has a good diabetes treatment effect.
Owner:SHANDONG UNIV

Equipment and method for detecting water locking performance of nursing pad

The invention discloses a device and method for detecting the water locking performance of a nursing pad, and relates to the field of material performance tests.The detection method comprises the following steps that S1, a nursing pad sample is fixed to a detection platform, a composite dynamic pressure sequence containing sine fluctuation, stepped pressurization and random disturbance is applied, constant-temperature liquid is injected into the sample synchronously, and the water locking amount is calculated; s2, scanning the three-dimensional distribution of liquid in real time, capturing the expansion state of a core body, triggering sudden stop when the edge leaks, and calculating the water locking efficiency; s3, taking an absorption core material, soaking the absorption core material in normal saline, performing centrifugal dewatering, and calculating the water retention capacity; and S4, constructing a three-level evaluation system output performance report. Composite multi-point pressure is adopted to simulate human body activity mechanics characteristics, a multi-mode sensing technology is combined to track the liquid three-dimensional permeation process in real time, the defects that a traditional method is single in pressure and insufficient in detection dimension are overcome, and dynamic process analysis support which cannot be achieved through traditional static detection is provided for product optimization.
Owner:JIANGSU AISHELUN MEDICAL TECH GRP CO LTD

Composition containing mesenchymal stem cells and application of composition in preparation of product for resisting premature ovarian failure

The invention belongs to the technical field of medicines, and particularly relates to a composition containing mesenchymal stem cells and application of the composition in preparation of products for resisting premature ovarian failure. The invention relates to a composition containing mesenchymal stem cells. The umbilical cord mesenchymal stem cell gel is prepared from the following components in percentage by weight: 10 percent of umbilical cord mesenchymal stem cells, 4 to 6 percent of human serum albumin stock solution, 1 to 2 percent of ginkgo biloba extract, 1 to 3 percent of coix seed oil, 2 to 2.5 percent of flavonol glycoside, 1.1 to 1.3 percent of vitamin E, 0.4 to 0.8 percent of glutathione, 0.5 to 1.5 percent of sodium hyaluronate, 0.5 to 1.0 percent of phycocyanin, 1.2 to 1.8 percent of zinc gluconate, 0.5 to 0.8 percent of heparin calcium, 0.1 to 0.3 percent of pH regulator and the balance of normal saline. The composition disclosed by the invention can be used for preparing products for resisting premature ovarian failure and has a very good effect.
Owner:深圳惠善生物科技有限公司

Method for detecting antibacterial property of worsted fabric

The invention discloses a method for detecting the antibacterial performance of a worsted fabric, and belongs to the technical field of cross fusion of textile material science and microbiological detection technology, and the method comprises the following steps: cutting a sample with a certain size and a regular shape from a to-be-detected worsted fabric, marking a plurality of different detection positions on the inner side and the outer side of the sample respectively, the method comprises the following steps: inoculating a test strain into a culture medium, placing a prepared sample in a sterile culture dish subjected to sterilization treatment, eluting each detection position marked on the inner and outer sides of the sample by using sterile normal saline, and calculating the antibacterial rates of different positions on the inner and outer sides of the sample by using a calculation formula, according to the detection method, the detection efficiency is improved, a multi-part result is obtained through a single process, and the antibacterial performance detection results of different positions on the inner side and the outer side of the worsted fabric can be obtained at the same time in the single detection process; the tedious process of single-side detection of the fabric or independent detection of the inner side and the outer side of the fabric in an existing method is avoided.
Owner:JIANGSU QIANJIAHUI TEXTILE TECH CO LTD

Salt-tolerant microbial agent as well as preparation method and application thereof

The invention discloses a salt-tolerant microbial agent as well as a preparation method and application thereof, and belongs to the technical field of fertilizers. The preparation method comprises the following steps: inoculating a microbial agent into a culture medium for culturing to obtain a bacterial suspension, and collecting thalli; resuspending the thalli by using sterile normal saline to obtain resuspended bacterial liquid; mixing the resuspended bacterial liquid with an embedding liquid to obtain a mixed liquid; dropwise adding the mixed solution into a CaCl2 solution, and curing; and drying to obtain the salt-tolerant microbial agent. The embedding liquid contains 1 to 3g / 100mL of sodium alginate and 1 to 3g / 100mL of polyvinyl alcohol. The influence of a high-salt environment on the microbial agent is isolated by utilizing a physical method, the tolerance of the microbial agent in the high-salt environment is improved, the activity and metabolism efficiency of the microbial agent are improved, and the technical bottleneck of thallus inactivation when a microbial fertilizer and a chemical fertilizer are compounded is solved.
Owner:CENT SOUTH UNIV

Direct in-scope suction system

The invention disclosed in this document presents a novel direct in-scope suction system designed for the retrieval of calculus fragments within the body. This system comprises two key components: a calculus fragments retrieval device and a pump unit. The calculus fragments retrieval device features a body with a single working channel that includes both an irrigation port and a suction port, which are connected to respective irrigation and suction pumps via elastomer-based rubber tubes. This setup allows for the controlled infusion of saline solution into the body lumens during lithotripsy procedures, ensuring clear visibility and fragment clearance. The retrieval device includes a trigger lever connected to a pincher tab. When the operator presses the trigger lever, the suction port is opened by releasing the pinched suction tube, increasing pressure inside the body.
Owner:BIORAD MEDISYS PTE LTD

Film water collection negative pressure system for antibacterial operation

The invention discloses a film water collection negative pressure system for an antibacterial operation. The film water collection negative pressure system comprises a water collection main body, a waterproof film and a negative pressure drainage tube. The shape of the water collecting main body is configured to surround a water collecting area on the outer side of a surgical incision on the body surface of a patient, and microporous structures facing the stoma of the human body are distributed on the water collecting main body; the water collecting main body and the water collecting area are covered with the waterproof thin film, the waterproof thin film is provided with a surgical operation opening corresponding to the stoma of the human body in position, and the waterproof thin film is further provided with a liquid passing hole facing the micropore structure; the head end of a tube body of the negative pressure drainage tube is connected with the micropore structure in an attached mode. And the tail end of the tube body of the negative pressure drainage tube is communicated and connected with a negative pressure source. Sterile normal saline for lavage incision can be prevented from flowing to an operating table, a bed sheet and the ground along the body of a patient, the sterile environment of an operation area is guaranteed, the risks of low body temperature, postoperative infection and the like in the operation of the patient are reduced, and the experience of the patient in the perioperative period is improved.
Owner:THE FIRST AFFILIATED HOSPITAL OF NAVAL MEDICAL UNIVERSITY OF CHINESE PEOPLES LIBERATION ARMY

Silk fibroin solution injection capable of forming gel in situ as well as preparation method and application of silk fibroin solution injection

The invention discloses a silk fibroin solution injection capable of forming gel in situ and a preparation method and application thereof.The preparation method comprises the following steps that a regenerated silk fibroin solution with the molecular weight of 100 kDa-250 kDa and a hydrogen bond breaker are evenly mixed to obtain a mixed solution, the mixed solution is subjected to quick-freezing supercooling crystallization and vacuum drying to obtain silk fibroin powder, and the silk fibroin powder is dried to obtain the silk fibroin solution injection capable of forming gel in situ. And sterilizing and dissolving in normal saline to obtain the silk fibroin solution injection. A hydrogen bond breaker is introduced into a high-molecular-weight regenerated silk fibroin solution, a beta folding structure between silk fibroin molecules is inhibited, damage to the silk fibroin molecules in the freeze-drying process is reduced through a quick-freezing and supercooling crystallization method, and aggregation of the silk fibroin molecules is further reduced; after redissolving, an injection is formed and injected into local tissues, the micromolecular hydrogen bond breaker quickly diffuses, and the large molecular weight regenerated silk fibroin recovers hydrogen bond interaction and then forms hydrogel in situ through physical crosslinking, so that in-vivo in-situ gelling of the silk fibroin is realized.
Owner:FAVORSUN MEDICAL TECH (SUZHOU) CO LTD

Preparation method of compound microbial fertilizer

The invention discloses a preparation method of a compound microbial fertilizer, and belongs to the technical field of microbial fertilizers, the preparation method comprises the steps of starch gelatinization, strain activation, shake-flask culture, immobilization, fermentation and material mixing; the immobilization comprises the following steps: centrifuging a paenibacillus polymyxa shake-flask culture, and collecting wet thalli; mixing the wet thalli with normal saline, stirring at room temperature, adding the gelatinized starch solution, and continuously stirring to obtain a mixed bacterial solution; stirring a calcium chloride aqueous solution at 30-35 DEG C, dropwise adding the mixed bacteria solution, continuously stirring after dropwise adding, filtering, and taking filter residues to obtain immobilized paenibacillus polymyxa; the compound microbial fertilizer prepared by the invention is high in viable count, and the viable count is slightly influenced by the content of each substance in the corn steep liquor.
Owner:SHANDONG SHOUGUANG JUNENG GOLDEN CORN CO LTD +2

Pulmonary tuberculosis sputum taking device

The invention discloses a pulmonary tuberculosis sputum taking device, which relates to the technical field of pulmonary tuberculosis sputum taking, specifically comprises a portable box, an adjustable sputum aspirator, a sputum storage tank, a sheath tube and a sputum taking tube, and is characterized in that a cavity for placing the adjustable sputum aspirator, a micro liquid pump, a control box, a liquid storage box and a storage drawer is formed in the portable box; the upper end and the lower end of the portable box are each fixedly provided with a fixing ring for installation of a bandage. The sputum taking tube is sleeved with the sheath tube for spraying normal saline or sodium bicarbonate solution, so that only one-time tube placement is needed in the sputum taking process, repeated tube placement is not needed, the comfort of a patient is improved, the end, making contact with the breathing inner wall of the patient, of the sputum taking tube is improved, a plurality of flexible contacts are designed, and the sputum taking tube is convenient to use. Therefore, when the sputum taking tube is in contact with the respiratory inner wall mucous membrane of a patient, the sputum taking tube is separated by the soft flexible contact, so that the end of the sputum taking tube cannot scratch the respiratory inner wall mucous membrane.
Owner:THE FIRST AFFILIATED HOSPITAL OF SHANTOU UNIV MEDICAL COLLEGE

Multi-angle operation sheath tube for arthroscopic surgery

The invention relates to the technical field of endoscopes, in particular to a multi-angle operation sheathing canal for arthroscopic surgery, which comprises an insertion tube and an observation tube arranged in the insertion tube, the insertion tube comprises an outer tube body, a protective cover arranged at the end part of the outer tube body, and a shifting and scraping part, a driving part and a cleaning part which are arranged in the insertion tube from left to right, and a spherical glass cover is clamped at the end part of the outer pipe body. According to the multi-angle operation sheathing canal for the arthroscopic surgery, a motor drives a disc and a shifting rod and drives a square frame to horizontally reciprocate, a linkage connecting rope pulls a line wheel, a volute spiral spring is utilized, a hanging strip can continuously swing, a cleaning part is synchronously triggered, a piston plate is driven to pressurize a liquid storage barrel, normal saline is forced to be injected into a hanging strip liquid passing groove through a liquid pipe, and the normal saline is injected into the hanging strip liquid passing groove; the flushing fluid is directionally sprayed from the fluid outlet hole, accurate cooperation of scraping action and flushing fluid spraying is achieved, dirt is mechanically scraped by swinging of the hanging strip, meanwhile, the observation window is scoured by high-pressure normal saline, and the cleaning efficiency is improved.
Owner:XINYI CITY PEOPLES HOSPITAL

Quick replaceable bronchoscope interventional operation robot

The invention provides a quick replaceable bronchoscope interventional operation robot. The quick replaceable bronchoscope interventional operation robot comprises a base, a bronchoscope structure, a driving device, a first supporting part and a second supporting part, the driving device is fixed on the base, one end of the bronchoscope structure is connected with the driving device, the first supporting part is connected with the bronchoscope structure, one end of the second supporting part is connected with the base, and the other end of the second supporting part is connected with the first supporting part; the bronchoscope structure comprises a bronchoscope which is arranged in a first supporting part in a penetrating manner; the shell is used for opening or closing the bronchoscope structure; a through hole is formed in the shell, is communicated with the bronchoscope and is used for introducing external normal saline into the bronchoscope. The bronchoscope structure is stably supported through the base, the first supporting part and the second supporting part, external normal saline can be introduced into the bronchoscope through the through hole in the shell, the bronchoscope can be flushed in time, it is guaranteed that the visual field of the bronchoscope is clear, and the precision and safety of an operation are improved.
Owner:SHANGHAI JIAOTONG UNIV +1

Double-sided anti-fog amplification mouth mirror

The invention relates to the technical field of medical instruments, in particular to a double-sided anti-fog amplification mouth mirror which comprises a mirror body, a rotary connecting mechanism, a micro-channel cleaning system and a handle assembly. A lens main body is formed by fixing a plane mirror (A surface) and an aspheric magnifying lens (B surface) in a back-to-back manner, and a steering engine drives a central connecting rod to realize quick switching of double functions. The lens body is further provided with a heating anti-fog module, the micro-channel system is integrated in the lens frame, the annular distribution cavity is of a double-layer independent structure, the upper layer is communicated with the inclined spraying holes, normal saline is directionally sprayed for preventing fog and removing dirt, and the surface of the lens body is clear through heating of the heating anti-fog module. And the lower layer is communicated with a suction hole to recycle dirt under negative pressure. The handle is integrated with a control button, a foot switch controls washing / suction separately, and single-hand operation is achieved. The problems of view limitation, mirror surface fogging, pollution and single function are systematically solved, and the diagnosis and treatment efficiency and accuracy are remarkably improved.
Owner:长沙市中医医院(长沙市第八医院)

Aerogel for promoting wound healing and preparation method thereof

The invention discloses an aerogel for promoting wound healing and a preparation method thereof. The preparation method of the gas comprises the following steps: (1) dissolving different matrix materials in water, normal saline or a buffer solution to obtain hydrogel with different proportions and different viscosities; and (2) fully mixing the pre-filled hydrogel obtained in the step (1) with single gas or combined gas to obtain the gel containing gas bubbles. The invention provides a preparation method of gas gel with different activities, the method is simple, the gas gel can be obtained by mixing pre-filled gel and gas, bubbles are loaded by using the viscosity of the gel, and efficient carrier gas is maintained, so that the problems of addition of a gas production material, low gas production rate, poor biocompatibility, limited production and the like in the existing gas gel technology are solved.
Owner:WUXI XISHAN NJU INSTITUTE OF APPLIED BIOTECHNOLOGY

Stem cell preparation for scalp hair follicle regeneration and preparation method thereof

The invention discloses a stem cell preparation for scalp hair follicle regeneration and a preparation method thereof, and relates to the technical field of biological agents, and the stem cell preparation comprises the following raw materials: exosome, normal saline, alpinetin extract and hydrogel. According to the stem cell preparation for scalp hair follicle regeneration and the preparation method of the stem cell preparation, mRNA, miRNA and protein carried by the exosome can act on hair follicle stem cells in a targeted mode, cell cycle related genes are activated, and cells are promoted to enter a proliferation period from a G0 period; meanwhile, by transmitting BMP, Notch and other signal molecules, hair follicle stem cells are inhibited from being differentiated into epidermal cells, the hair follicle stem cells are induced to be differentiated into hair follicle specific cells, and reconstruction of a hair follicle structure is promoted; anti-inflammatory factors in the exosome can inhibit excessive activation of fibroblasts around hair follicles, reduce collagenous fiber deposition and relieve inhibition of fibrosis on hair follicle regeneration; meanwhile, the levels of TNF-alpha, IL-6 and other proinflammatory factors are reduced, and a suitable growth environment is provided for hair follicle stem cells.
Owner:XINJIANG SAIER THOMAS BIOTECHNOLOGY CO LTD

Device and method for measuring cross sectional area of tendon

The invention belongs to the technical field of medical instrument evaluation, particularly relates to a tendon cross-sectional area measuring device and a tendon cross-sectional area measuring method, and provides the tendon cross-sectional area measuring device and the tendon cross-sectional area measuring method on the basis of a volumetric method and a die forming technology. The long and thin cylindrical measuring cylinder is used for containing normal saline, the pressure sensor is used for measuring the hydraulic pressure change caused by the fact that the tendon is immersed in the normal saline, then the liquid volume change is obtained, and the average cross sectional area of the tendon under the corresponding displacement is obtained based on the displacement of the tendon immersed in the liquid. Further, the minimum point of the tendon cross section area is accurately measured, and a reference is provided for a later tensile test.
Owner:SHANDONG INST OF MEDICAL DEVICES & DRUG PACKAGING INSPECTION

Mineralized collagen hydrogel microspheres, preparation method thereof and bone repair material

The invention relates to the technical field of medical instruments, and discloses mineralized collagen hydrogel microspheres, a preparation method thereof and a bone repair material, the mineralized collagen hydrogel microspheres are prepared from mineralized collagen and sodium alginate composite liquid through electrospray, sodium alginate serves as a carrier of mineralized collagen, the degradation rate of the mineralized collagen is remarkably reduced, and the bone repair effect is improved. Meanwhile, the gel microspheres also have a higher specific surface area, so that the attached cells can quickly form tissues; according to the bone repair material, normal saline and mineralized collagen hydrogel microspheres are used, mineralized collagen in the mineralized collagen hydrogel microspheres can remarkably improve the corrosion resistance of sodium alginate in the normal saline, and the slow release effect of hydrogel in the mineralized collagen hydrogel microspheres can be remarkably improved.
Owner:JIAXING RUIQING MEDICAL TECH CO LTD

A puncture-free hemorrhoid electrolysis therapeutic instrument and a use method thereof

The present application relates to the technical field of electrolysis therapeutic instrument, and proposes a kind of free puncture hemorrhoid electrolysis therapeutic instrument, including power supply, for providing conversion electric energy to the therapeutic instrument;Control handle, electrically connected with power supply, and the end is equipped with control display system, for grasping and controlling the size of current output;Therapeutic soft pad: electrically connected with power supply, and its upper surface is covered with medical gauze, and is placed in the lower surface of the thigh of the load end of patient, and the thigh skin is fully contacted with the medical gauze added with physiological saline, to form current loop;Free puncture detection expansion probe mechanism, installed on control handle, for tissue examination of anal part and free puncture contact hemorrhoid part, output micro-current.The beneficial effects of the present application are: no need for acupuncture treatment, can reduce the pain and bleeding of patient during treatment, improve the safety of treatment, and use conveniently, treatment is fast.
Owner:BEIJING ZHUANG ZHI MEDICAL EQUIP LTD CO

Absorbent body and absorbent article

The present invention relates to an absorber including a first water absorption layer, and a second water absorption layer laminated on the first water absorption layer, in which the first water absorption layer contains water-absorbent resin particles (I) having a water retention capacity of physiological saline of 32 to 80 g / g and a one-minute value of a lockup height of 1.6 cm or less, and the second water absorption layer contains water-absorbent resin particles (II) having a one-minute value of a lockup height of more than 1.6 cm.
Owner:SUMITOMO SEIKA CHEM CO LTD

Method for preparing fermented feed by using bovine intestinal lactobacillus

The invention belongs to the technical field of fermented feeds, and relates to a method for preparing a fermented feed by using bovine intestinal lactobacillus, and the method specifically comprises the following steps: step 1, mixing intestinal contents with pre-sterilized normal saline, filtering, and adding amino acids; 2, adjusting the pH value of the intestinal tract solution, carrying out anaerobic culture, and then mixing with an adsorption carrier to obtain a solidified microbial inoculum; step 3, mixing the feed, the curing microbial inoculum and the filtrate in the step 2, and fermenting according to three stages; 4, after fermentation is completed, drying is conducted to obtain the fermented feed; through the synergistic effect of various technologies such as specific strain screening, a multi-stage dynamic regulation and control process and compound bacteriostasis, the core problems of poor strain adaptability, low fermentation efficiency, easiness in pollution, high storage cost and the like in the existing fermented feed are systematically solved.
Owner:GANSU AGRI UNIV

Use of exercise-induced sweat extract for the preparation of a medicament for the treatment, prevention or alleviation of depression, anxiety

PendingCN122376622AHigh dosesHealthy subjects
The application provides an application of a motion-induced sweat extract in preparation of a medicine for treating, relieving or preventing depression and / or anxiety, and belongs to the field of biological medicine. Specifically, sweat is induced by making a healthy subject perform aerobic exercise of a specific intensity (such as 60%-80% of maximum heart rate), the sweat is collected and eluted by physiological saline, centrifuged and filtered to obtain a biologically active sweat extract. The extract is analyzed by transcriptomics and reverse transcription method to predict the anti-depression potential, and it is proved by in-vivo animal experiments that the extract can significantly improve the anhedonia, behavioral despair and anxiety-like behavior of a depression model mouse, and the effect of a high dose is equivalent to that of a first-line drug fluoxetine. The preparation raw material provided by the application is natural and safe, the preparation process is simple and the cost is low, and a new, easy-to-promote alternative strategy is provided for the prevention and treatment of depression.
Owner:WUHAN SPORTS UNIV

Chondrocytes for treating osteoarthritis and preparation method and application thereof

The present invention discloses chondrocytes for treating osteoarthritis, and a preparation method and application thereof, which relate to the field of biomedical technology, and include the following process: taking mesenchymal stem cells and collagen microspheres for mixing, inoculating them in a culture device for culture, adding induction culture medium for induction culture, harvesting, and obtaining chondrocytes. The present invention mixes mesenchymal stem cells with collagen microspheres so that the mesenchymal stem cells are adsorbed / inoculated on the collagen microspheres, the cells are amplified, and cultured induction is performed. The mesenchymal stem cells are induced to form chondrocytes to obtain chondrocytes, and the product is collected, resuspended in 0.9% physiological saline, and injected locally into the bone and joints. It can be used for the treatment of osteoarthritis, reducing the adverse reactions caused by the use of traditional drugs and the damage caused by surgical methods. Chondrocytes fundamentally solve the cause of osteoarthritis by repairing cartilage through cells, and have a significant therapeutic effect.
Owner:JILIN JIEXUAN LIFE TECHNOLOGY CO LTD

General surgery operation trauma nursing device

The application discloses a general surgery operation trauma nursing device and belongs to the technical field of medical devices, which comprises a body, and a separation component is arranged on the inside and outside of an operating table, wherein the separation component comprises a collecting frame which is inserted into the operating table, a scraping ring is fixedly connected to the inside of the collecting frame, a protective cover is arranged in the operating table, and a driving motor is arranged in the protective cover. The magnetic block ring is arranged to adsorb metal foreign matters, and the rotating disc accelerates the flow of liquid after rotation, so that the foreign matters and necrotic tissues are quickly separated. Since the magnet ring can adsorb the metal foreign matters during rotation, the foreign matters and necrotic tissues are separated, the foreign matters carrying the necrotic tissues are prevented from sinking into the physiological saline and being difficult to separate, and the rotating disc only accelerates the flow speed of the physiological saline during stirring of the physiological saline, so that the over-dissolution of the necrotic tissues is reduced, and the separation effect of the foreign matters and the necrotic tissues is guaranteed.
Owner:THE FIRST AFFILIATED HOSPITAL OF ARMY MEDICAL UNIV

Preparation method and application of biochar immobilized microbial agent

The invention discloses a preparation method and application of a biochar immobilized microbial agent, and relates to the technical field of immobilized microbial treatment.The preparation method mainly comprises the following steps that a bacterial strain serratia marcescens QZB-1 is activated and then centrifugally collected, and a bacterial suspension is prepared with sterile water; fully and uniformly mixing the sterilized biochar with the bacterial suspension, and oscillating for 24 hours; adding sodium alginate into the mixture, uniformly mixing, slowly dripping the mixture into a 3% calcium chloride solution by using a rubber head suction tube, and standing and cross-linking for 12 hours to prepare a biochar immobilized microbial agent; and finally, flushing away the calcium chloride solution remained on the surface of the biochar immobilized microbial agent by using sterilized normal saline, and storing in the sterilized normal saline for later use. The biochar immobilized microbial agent disclosed by the invention has relatively high removal capacity on Mn (II), and has a very good application prospect in manganese pollution treatment.
Owner:GUANGXI UNIV