259 results about "Drugs solution" patented technology

The invention relates to the technical field of pharmaceutical preparations, and provides a minoxidil film coating agent as well as a preparation method and application thereof. The minoxidil film coating agent provided by the invention comprises 40-60% of propylene glycol, 3-7% of polyvinyl alcohol, 20-30% of ethanol, 1-7% of minoxidil and the balance of water. According to the invention, propylene glycol is taken as a solvent, a plasticizer and a transdermal absorption enhancer, polyvinyl alcohol is taken as a film-forming material, and ethanol is taken as a volatile agent, after administration, ethanol is volatilized to promote film formation of polyvinyl alcohol, and propylene glycol enhances the plasticity of the formed film, so that the effect of reducing liquid medicine loss is achieved, the local medicine concentration is increased, and the bioavailability is improved. The minoxidil liniment disclosed by the invention has excellent skin permeability, can effectively convey a medicine to a required part, and can ensure that the medicine is released at a fixed position of the skin and is accurately administered in a medicine release process, so that the stimulation of liquid medicine flow to other parts is reduced, and a good treatment effect is achieved.

The present application discloses an ultra-high-speed jet drug delivery device, which relates to the field of drug delivery technology and includes: a jet parameter setting module for determining the direction and speed of the jet according to the drug delivery requirements; a high-energy current module for generating high-energy current to make the metal wire reach a high-temperature state instantly, driving the drug solution to form a high-speed fluid; a nozzle for converting the high-speed fluid into a jet according to the direction and speed of the jet determined by the jet parameter setting module; a sensor module for monitoring the distribution of the drug solution in the body in real time; and a precision delivery module for controlling the jet parameter setting module in real time to adjust the direction and speed of the jet according to the distribution of the drug solution in the body and the drug delivery requirements. In the present application, electric explosion technology is used to form a high-speed jet, providing powerful kinetic energy to effectively penetrate human tissue, achieve precise drug delivery to deep target areas, and combine with sensors to ensure that the drug jet is accurately delivered to deep tissues.

The invention belongs to the technical field of anhydrous emulsions, and discloses an anhydrous self-emulsifying drug-loaded emulsion based on a deep eutectic solvent and a preparation method thereof.The preparation method comprises the following steps that 1, betaine and a hydrogen bond donor are mixed, the deep eutectic solvent is prepared through a mixed heating method, a drug is dissolved in the deep eutectic solvent, and a drug solution is prepared; the hydrogen bond donor is levulinic acid or lactic acid; (2) mixing Tween 80 and Span 80 according to a mass ratio of (1-2): 1 to obtain a surfactant, adding absolute ethyl alcohol as a co-emulsifier, adding isopropyl myristate, and uniformly stirring and mixing to obtain a dispersion liquid; and (3) dropwise adding the drug solution in the step (1) into the dispersion liquid in the step (2), and stirring at the same time to finally form the anhydrous self-emulsifying drug-loaded emulsion. According to the invention, the loading capacity, the stability and the bioavailability of the medicine can be obviously improved; in addition, the efficiency of transdermal drug delivery of the emulsion is high, and the emulsion can be applied to skin external preparations.

A system and method for enhanced aerosol drug delivery during high flow nasal cannula (HFNC) therapy. The system comprises a breath enhanced jet nebulizer (BEJN) connected to a high flow medical breathing gas supply supplying breathing gas to the BEJN at flow rates of 5 L / min to 60 L / min, a nebulization gas supply, a drug infusion device that supplies a drug solution to the nebulizer for the delivery of nebulized drug to a patient. All the breathing gas and nebulized drug solution delivered to the patient passes through the BEJN. The rate of drug delivery increases with increases in the flow rate of the medical breathing gas supply and increases in infusion pump flow rates. The drug solution infusion rate is between 5 mL / hour and 50 mL / hour. This system and method enable efficient aerosol drug delivery to patients during HFNC therapy for prolonged periods, improving treatment outcomes.

The utility model discloses a biopharmaceutical sampler which comprises a sampling barrel, a push rod, a sealing plug, a sampling opening, a measuring scale, a protective cover, a sealing mechanism, a filter layer, a cleaning brush, scale marks, an exhaust valve and a fixing ring, the biopharmaceutical sampling device is reasonable and simple in structure, low in production cost, convenient to install and complete in function, the biopharmaceutical sampling amount can be accurately controlled through the arranged measuring scale and scale marks, and the accuracy of experimental data is improved; impurities in liquid medicine are effectively filtered through the filter layer, the purity of sampling is ensured, and the accuracy of follow-up detection and analysis is facilitated; the inner wall of the sampling barrel is convenient to clean through the cleaning brush, cross contamination among different samples is avoided, and independence and accuracy of sampling each time are guaranteed.

The invention relates to the technical field of extracellular vesicles, in particular to an extracellular vesicle active drug loading method which comprises the following preparation steps: S1, collecting cell supernatant, collecting the cell supernatant under the condition of 4 DEG C, and performing multi-stage centrifugation to remove impurities to obtain purified extracellular vesicles; s2, dissolving a target drug in a corresponding solvent to prepare a drug solution with the concentration of 0.1-5 mg / mL; s3, mixing the purified extracellular vesicles obtained in S1 with the medicine solution obtained in S2 according to the volume ratio of 1: 1, and performing low-frequency ultrasonic treatment in a pulse mode under the ice bath condition of 4 DEG C; s4, incubating the mixed system subjected to ultrasonic treatment at 37 DEG C for 25-35 minutes, and meanwhile, adding a cholesterol solution with the final concentration of 0.005-0.01% to assist membrane repair; the problems of contradiction between the drug loading efficiency and the integrity of the extracellular vesicles, poor drug universality, low purification efficiency and insufficient application stability in the existing active drug loading technology of the extracellular vesicles are specifically solved through the whole process optimization of precise purification, efficient drug loading, directional repair and deep refining.

The invention discloses a pH response hydrogel microneedle, which comprises a microneedle substrate, microneedle tips are arranged on the microneedle substrate, the height of the microneedle tips is 100-1600 microns, the diameter of the tip ends of the microneedle tips is 5-15 microns, and the density of the microneedle tips is 200-1000 pieces per square centimeter. The preparation method comprises the following steps: preparing a hyaluronic acid solution for the microneedle substrate, preparing a methacrylated chondroitin sulfate solution for the microneedle tip, preparing methacrylated orthoester, preparing orthoester, preparing a non-steroidal anti-inflammatory drug solution, preparing a microneedle tip solution, preparing the microneedle and demolding the microneedle to prepare the complete soluble microneedle patch. The invention has the advantages of high drug efficiency, high efficiency in dissolving fat / water drugs, and long-acting slow release.

The invention discloses an intelligent drug delivery and release system based on a micro-fluidic technology, which comprises a micro-fluidic chip, a fluid chip used for accurately controlling and analyzing a micro volume, a micro-machined channel and a micro-machined cavity, a liquid medicine storage device used for mixing, separating, reacting and detecting fluids on a micro scale, a liquid medicine storage device used for storing and managing drugs and a liquid medicine release device used for releasing the drugs. A micro-cavity is arranged in the body, a total liquid storage device and a fluid control module are arranged on the outer side of the body and used for accurately controlling the flowing and releasing speed of a medicine solution, and a monitoring sensor is used for monitoring concentration indexes of medicine in the body of a patient in real time and used for monitoring physiological parameters and medicine concentration; the micro-fluidic chip, the liquid medicine storage device, the fluid control module, the monitoring sensor, the control module, the power supply module and the connecting pipeline are matched for use, the liquid medicine storage device and the fluid control module obtain the medicine concentration, the release amount and the conveying rate of the medicine are calculated, and it can be guaranteed that the medicine concentration of a diseased area is stable.

The invention discloses radiopharmaceutical split charging equipment and a split charging method. The equipment comprises an upper shell and a lower shell, a base used for containing a stock solution bottle distribution tank is arranged at the bottom of the lower shell, a cover opening mechanism used for opening a tank cover of the stock solution bottle distribution tank and a needling mechanism used for extracting stock solution in a stock solution bottle are arranged above the base, and a horizontal sliding mechanism is arranged at the bottom of the base. The driving mechanism is used for driving the base to slide to the position under the uncovering mechanism and the needling mechanism. A stock solution extracting needle is fixed to the needling mechanism and used for extracting stock solution in a stock solution bottle and then transferring the stock solution into a liquid medicine diluting bottle in the upper shell, and then split charging is achieved through a liquid medicine split charging and transferring guide pipe in the upper shell. Opening of a stock solution bottle distribution tank and extraction of stock solution in a stock solution bottle can be sequentially achieved in the lower shell through the uncovering mechanism and the needling mechanism, the stock solution distribution tank and the stock solution in the stock solution bottle can be matched with a liquid medicine subpackaging and transferring guide pipe in the upper shell, all-directional protection subpackaging is achieved, the protection effect in the whole process is good, and harm to medical staff is greatly reduced.

An information management system (10) comprises a drug solution administration device (12) and an information management device (14). The drug solution administration device comprises a transmission control unit (104) that transmits information acquired using a sensor (86) provided to the drug solution administration device to the information management device. The information management device comprises a reception control unit (124) that receives the information transmitted by the transmission control unit and a determination unit (128) that, on the basis of the information received by the reception control unit, determines whether a drug solution administration amount has reached a predetermined required administration amount.

The invention relates to the technical field of atomizers, in particular to an intelligent atomization control system for medicine dosage homogenization, which comprises a temperature feedback control module, a laser granularity measurement module, an airflow fluctuation compensation module, a flow regulation module and a data analysis module. By intelligently controlling the flow, granularity, airflow and temperature of liquid medicine, accurate adjustment of the atomization process can be achieved, it is ensured that medicine is evenly and stably released in the whole treatment process, waste of the liquid medicine is remarkably reduced, the medicine utilization rate is increased, and by monitoring the temperature change in real time, the atomization effect is improved. The flow is adjusted to cope with the influence of temperature fluctuation on the liquid medicine flow characteristic and the atomization effect, medicine conveying stability in different environments is guaranteed, meanwhile, based on particle size control, airflow and flow can be adjusted in time to guarantee consistency of atomized particles, uneven medicine dosage caused by particle size fluctuation is avoided, and through airflow fluctuation compensation, the atomization effect is improved. It can be ensured that the influence on medicine flow is minimized when airflow is unstable, and dosage instability is avoided.

A pyridine amide compound-containing composition and a pharmaceutical composition, a preparation method therefor and a use thereof. The composition comprises an active ingredient and at least one matrix material, wherein the active ingredient is a compound represented by formula I or a pharmaceutically acceptable salt, a stereoisomer, a solvate, an isotopically labeled compound, a polymorph, a metabolite or a prodrug thereof. The composition has a high drug loading capacity, improves drug solubility, and has good stability. The in vivo bioavailability of the composition can reach the same level of bioavailability as that of a clear drug solution.

Provided is a drug solution administration device (1) for administering a drug solution filled in a reservoir (18), the drug solution administration device (1) comprising a pump body (10) provided with: a pump for transporting the drug solution filled in the reservoir (18); a rechargeable battery (42) for supplying power for driving the pump; a measurement unit (76) for measuring the remaining charge of the rechargeable battery (42); and a control unit (71). If the remaining charge of the rechargeable battery (42) measured by the measurement unit (76) is greater than a predetermined threshold value, the control unit (71) notifies a user that the rechargeable battery (42) is fully charged.

The present application belongs to the technical field of pharmaceutical preparations, and specifically provides a compound SYN045 soft capsule and a preparation method thereof. The present application adopts a fixed proportion of plant oil and polyoxyethylene glyceryl oleate combination to prepare the content, which helps to reduce the degradation of SYN045 in the content drug solution, ensures the stability of the active ingredient, and obtains a compound SYN045 soft capsule with good drug dissolution, high drug content, low impurity generation, and high bioavailability. Further, through prescription optimization of the soft capsule shell, a fixed proportion of plasticizer is selected, the mass ratio of glycerol and sorbitol is 1:2-3, the transfer of the compound SYN045 to the soft capsule shell is reduced, and thus the quality stability problem of the soft capsule preparation product during drug storage is solved.

The invention discloses a coating preparation method capable of regulating and controlling the morphology of a coating. The coating preparation method is used for spraying on an instrument. A drug solution used in the preparation method of the coating comprises at least one solvent, a drug active ingredient and an excipient in a preset proportion are added into the solvent, when only one solvent is used, the solvent is a polar and high-volatility solvent A, stirring and ultrasonic oscillation are carried out at room temperature so as to uniformly dissolve the solvent A, and the drug solution is obtained, when the medicine solution is sprayed, the spraying flow and the moving speed of a spray head are adjusted through external spraying equipment according to a preset standard so as to spray at least one layer of medicine solution on an external instrument, and therefore the preset coating morphology is formed on the surface of the instrument through the medicine. The method has the advantages that the microstructure of the coating can be controlled to improve the stability of the coating; therefore, the release effect of the medicine is ensured, and the release behavior and the tissue retention time of the medicine in various lumen stenosis diseases can meet the delivery requirements required by clinical treatment.

This invention discloses a multi-stage dosing device and method for a concentrated liquid flocculation tank, relating to the technical field of dosing equipment. It includes: a fixed frame, disposed on the top of the tank, with a track rod fixedly connected to the end of the fixed frame, and a housing slidably connected to the track rod; a ring-shaped airbag fixedly connected to the top edge of the housing; a dosing device, arranged in a circumferential array on the housing, comprising: a ring pipe, with a delivery pipe circumferentially connected to the ring pipe, one end of the delivery pipe connected to the ring pipe and the other end fixedly connected to the housing and extending into the tank; an inlet device for supplying the drug solution to the ring pipe; and a slow-release device, arranged in a circumferential array on the housing, with an opening and closing device on the housing for adjusting the drug output of the slow-release device.

The invention provides a special lung atomization therapeutic apparatus for the internal medicine of traditional Chinese medicine, and relates to the technical field of medical instruments, the special lung atomization therapeutic apparatus comprises an atomizer body, an atomization tank, a mist discharging pipe and a connecting pipe, the connecting pipe is inserted into a connecting plug at the bottom end of the atomization tank, and the other end of the connecting pipe is inserted into the air outlet end of the atomizer body; the double-cavity isolation type atomization tank is adopted, and aiming at the scene that salbutamol sulfate, budesonide and the like are compatible but need to be dosed for several times, through the design of the upper-layer independent medicine storage cavity, the lower-layer independent medicine storage cavity and the isolation gas circuit, the medicine can be dosed for several times, and the medicine can be dosed for several times. After the first liquid medicine is atomized, treatment is not required to be interrupted to replace a container or detach an air pipe, and the second medicine can be quickly switched only by cleaning the mask, so that the problems of tedious operation and treatment interruption of fractional atomization of a single medicine tank are solved, and tiny physical and chemical influence possibly caused by advanced mixing of a large amount of liquid medicine is avoided; and meanwhile, the operation time in the emergency scene is remarkably shortened.

The invention belongs to the technical field of medicines, and discloses a betahistine mesylate oral soluble film agent for treating meniere disease, meniere syndrome and vertigo symptoms caused by vertigo and a preparation process thereof, the preparation process comprises the following steps: (1) adding betahistine mesylate into purified water; (2) adding glycerol, citric acid, sucralose, liquid orange-flavored essence and sunset yellow into the raw material medicine solution; (3) taking HPMC-E15, dispersing the HPMC-E15 in purified water, and adding HPC-LXF for thickening; (4) adding the medicine-containing solution into the blank glue solution; (5) degassing; (6) coating; and (7) cutting and packaging. Compared with a common tablet, the oral soluble film disclosed by the invention has a higher release rate, and can enter a body through a sublingual vein way in addition to a conventional gastrointestinal tract absorption way after being dissolved in an oral cavity, so that the bioavailability is increased; under the condition of stability acceleration, the compound has a better impurity level, and the preparation process is simple to operate, high in repeatability and suitable for industrial large-scale production.

The invention relates to a preparation method of a tranexamic acid hydrogel microneedle. The preparation method comprises the following steps: 1) preparing a PDMS microneedle female template; 2) preparing a blank hydrogel microneedle; 3) preparation of the drug-containing hydrogel microneedle: dissolving tranexamic acid and derivatives or analogues thereof in ultrapure water, with the content range of the tranexamic acid and derivatives or analogues thereof being 0.1-30 mg / tablet, and preparing a drug solution with the mass concentration of the tranexamic acid and derivatives or analogues thereof being 0.1 g / mL, and (3) uniformly pouring the medicine solution into the blank hydrogel microneedle mold prepared in the step (2), then drying and forming at 37 DEG C, and finally, demolding the dried microneedle from the mold to obtain the tranexamic acid hydrogel microneedle. According to the tranexamic acid hydrogel microneedle, tranexamic acid can directly reach a skin basal layer, the tranexamic acid hydrogel microneedle can load and deliver more tranexamic acid, the treatment effect is remarkably enhanced, long-time slow release is achieved, and the tranexamic acid hydrogel microneedle has remarkable social and economic benefits.

The application discloses a breath actuated inhaler. The inhaler comprises a main housing having a suction port at a distal end, a canister storing a drug solution and disposed axially within the main housing, and a force retention unit attached to the main housing and engaged with the canister, comprising an upper housing having an air intake structure disposed at a proximal end, the air inlet structure and the suction port form an air circulation path, so that the force maintaining unit responds to inhalation of a user to start the tank; wherein the air inlet structure comprises at least two holes with main openings, and the at least two holes are annularly arranged at the near end of the upper shell in an end-to-end connection mode, so that the main openings of all the holes cannot be completely covered when fingers are placed on the end face of the near end during inhalation of a user.

To provide a personal dialysis machine that allows for visual confirmation of the remaining amount of concentrated dialysis solution with a simple configuration, while suppressing cost increases. [Solution] The personal dialysis machine 100 includes drug solution tanks 95, 96 and drug solution solenoid valves 81, 82 for storing drug solution for cleaning the piping 5, and concentrate tanks 93, 94 and concentrate solenoid valves 83, 84 for storing concentrate for dialysis fluid, and includes a drug solution concentrate usage determination unit 51 that determines the amount of at least one of the drug solution and concentrate that has been drawn up by the pump 86, a drug solution concentrate remaining amount calculation unit 52 that calculates the remaining amount of drug solution concentrate based on the amount determined by the drug solution concentrate usage determination unit 51, a drug solution concentrate remaining amount determination unit 55 that determines whether the remaining amount of drug solution concentrate is less than a predetermined standard amount, and a display unit 60 that displays a fact if the remaining amount of drug solution concentrate is less than a predetermined standard amount.

A cleaning / disinfecting device 1 comprises: a device body 2 capable of holding a drug solution bottle unit 7 to which are attached first to third color labels 19a -19c; a non-contact type color sensor 9 that detects each color of the first to third color labels 19a -19c in accordance with the position of the drug solution bottle unit 7 which moves inside the device body 2; and a processor 10a that determines the position of the drug solution bottle unit 7 on the basis of a detection signal from the color sensor 9.

The utility model discloses a portable medicine atomization device which comprises a pipe body shell, a bearing groove is formed in the top end of the pipe body shell, a containing tank is assembled on the bearing groove, a butt joint opening is formed in one side of the containing tank, and a sealing cover is arranged at the top of the containing tank. An ultrasonic wafer is arranged in the center of the containing tank, and an ultrasonic conduction groove is formed in the top end of the center of the pipe body shell and connected with the ultrasonic wafer. The utility model relates to the technical field of atomization equipment, and the portable medicine atomization equipment adopts an ultrasonic atomization mode to atomize liquid medicine, is simple in structure, is smaller in structure and convenient to carry compared with a high-pressure atomization mode, further divides a containing tank into a medicine containing groove and a vent groove through a sealing plate integrally arranged on the containing tank, and is convenient to carry. Through the arrangement of the double one-way valves, when a person breathes, medicine atomization jet flow is blocked and started, and a user can better adapt to the rhythm of atomization breathing.

In one embodiment, a method includes obtaining a measurement representative of an electrical impedance within a fluid channel of an implantable medical device; and processing the measurements to determine whether the implantable medical device is perfused for implantation in a recipient. The implantable medical device may include: an implantable drug reservoir having a loading port for receiving a drug solution; a drug delivery lumen having at least one release port and configured to be implanted within a recipient; and an intermediate drug lumen extending from the implantable drug reservoir to the drug delivery lumen to form a fluid path between the loading port and the at least one release port. The implantable medical device is configured to be infused with a drug prior to implantation in a recipient. The fluid path is electrically discontinuous in the absence of the conductive solution.

The utility model relates to the technical field of medicine feeders, in particular to a portable medicine feeder for mental patients, which comprises a tube body, a push plate is arranged on the inner side wall of the tube body, one end of the push plate is fixedly connected with a storage frame, and a storage rod is slidably connected into the storage frame. According to the portable medicine feeder for the mental patient, through the arrangement of the storage frame, the storage rod, a limiting sliding block and a limiting clamping block, when the portable medicine feeder is used, a user can manually push the storage rod, the storage rod moves to drive the limiting sliding block to slide in the storage frame, and after the storage rod is pushed to a certain position, the limiting clamping block can be clamped into a groove hole in the storage frame; the storage rod is fixed in the storage frame, so that the overall length of the device is adjusted, the effect of carrying the device is achieved, and the situation that when a user carries the device into a bag, articles in the bag are prone to squeezing the device, liquid medicine is prone to seeping, and subsequent normal medicine feeding is affected is avoided.

The invention discloses a montelukast sodium granular preparation and a preparation method thereof, and the preparation method comprises the following steps: dissolving montelukast sodium and mannitol in purified water in proportion to obtain a liquid medicine; and spraying the liquid medicine on the surface of spray-dried mannitol in a fluidized state, drying, and finishing to obtain the montelukast sodium granules. The montelukast sodium granular preparation prepared by the preparation method has the characteristics of good stability, few types of auxiliary materials, low production cost, high production efficiency, high bioavailability and the like, and is more suitable for children to use and industrial production.

The utility model belongs to the technical field of biological medicine extraction tools, and particularly relates to a biological medicine extraction device which comprises a heating container, a medicine loading assembly is connected to the inner side of the heating container in a sleeved mode, the medicine loading assembly comprises a filter cylinder body, a connecting cylinder and a plugging cover, and a connecting ring is fixed to the bottom of the filter cylinder body. A filter cone is fixed to the inner wall of the connecting ring, a supporting rod is fixed to the bottom of the connecting ring, a connecting cylinder is fixed to the top of the filter cylinder body, and a plugging cover is inserted into the inner side of the connecting cylinder. The inner side of the filter cylinder body is filled with medicine materials, through the arranged filter cylinder body, the situation that residues of the medicine materials enter external liquid can be avoided, inconvenience caused by the fact that medicine liquid needs to be filtered or a heating container needs to be cleaned subsequently is avoided, meanwhile, the space of the inner side of the filter cylinder body is large, the liquid can make full contact with the filled medicine materials, and the medicine materials are not prone to falling off. And medicine residues can be cleaned by taking out the filter cartridge main body subsequently.

The invention discloses a rosaxostat orally disintegrating tablet and a preparation method thereof. The preparation method of the orally disintegrating tablet is selected from one of a freeze-drying method, a tabletting method and a melting method. The prescription of the freeze-drying method comprises the rosaxostat or rosaxostat salt, a skeleton supporting agent, an adhesive, a suspending aid and a surfactant. According to the preparation formula and the preparation process, the defect that the content uniformity of the prepared tablets is poor due to the fact that the uniformity of intermediate liquid medicine is poor in the preparation process can be overcome, and the disintegration time limit of the rosaxostat orally disintegrating tablets, especially the rosaxostat freeze-dried orally disintegrating tablets, is further prolonged; the medicine is especially suitable for old people, children, patients with dysphagia and people with inconvenience in taking water to take medicine; the bioavailability is high; the rosaxostat orally disintegrating tablet is simple in material, moderate in tablet weight, good in appearance, good in taste, fast in disintegration, simple in preparation process and suitable for industrial mass production.

The invention discloses a mesalazine microcrystalline capsule and a preparation method thereof, and belongs to the technical field of microcapsules. The mesalazine microcrystal capsule comprises an HPMCAS shell, and mesalazine microcrystals are loaded in the HPMCAS shell. The preparation method comprises the following steps: dissolving mesalazine in dimethyl sulfoxide to obtain a medicine solution, dissolving HPMCAS in ethyl acetate to obtain an anti-solvent, adding the medicine solution into the anti-solvent, and carrying out ultrasonication to obtain mesalazine microcrystals; the preparation method comprises the following steps: dissolving HPMCAS in ethyl acetate to obtain a shell material solution, dispersing mesalazine microcrystals in the shell material solution to obtain an oil phase, and dispersing the oil phase in a water phase by adopting a microfluidic technology to prepare the mesalazine microcrystal capsule. The mesalazine microcrystal is good in monodispersity and can release a large number of drugs in a concentrated mode. In the preparation process, the organic solvent in the oil-phase liquid drops is continuously diffused into the external continuous-phase fluid, the concentration of the shell material is increased until the shell material is cured into a shell, and the microcapsules with uniform particle sizes are prepared.

The utility model relates to the technical field of infusion apparatuses, in particular to an infusion apparatus with a filtering and dosing structure, which comprises an upper infusion tube, a filter cartridge, a lower infusion tube, a coarse filter layer, a fine filter layer, an ultrafiltration layer and a flushing component, the filter cartridge is connected with the upper infusion tube, the lower infusion tube is connected with the filter cartridge, the coarse filter layer is connected with the filter cartridge, the fine filter layer is connected with the coarse filter layer, and the ultrafiltration layer is connected with the flushing component. The ultra-filtration layer is connected with the fine filtration layer, the flushing component is arranged on the filter cartridge, the coarse filtration layer is used for intercepting large-particle impurities, the fine filtration layer is used for further filtering small particles, and finally, the ultra-filtration layer is made of a nano-scale filtration material, so that the purity of a liquid medicine solution is ensured; the filtered liquid medicine is input into a human body through the lower infusion tube and the connecting needle head, so that the influence of impurities in the liquid medicine on the human body is avoided.