84 results about "Vaginal disease" patented technology

A speculum for the electropharmacological treatment of vaginal diseases has a pair of elongated blades interconnected such that an opening adapted for observation and passage of instruments is defined between the blades. There is at least one electrode connected to one of the blades on an inner face of the blade. The electrode has a proximal insulated portion and a distal uninsulated portion. To treat vaginal diseases, the speculum is placed in a vagina so that the electrode is located proximate to the vaginal disease, and a drug solution is injected into the vagina. An electric current is then applied to the electrode, which causes the migration of the drug solution toward the vaginal disease.

The invention discloses a Lactobacillus crispatus 262-1 and its application in gynecological diseases. The Lactobacillus crispatus 262-1 is a new Lactobacillus crispatus strain, and has a preservation number of CGMCCNo.6469 in China General Microbiological Culture Collection Center. The Lactobacillus crispatus 262-1 has the advantages of strong acid and H2O2 production ability, strong adherence to vaginal epithelial cells, substantial resistance on bacterial vaginal diseases and various vaginal gynecological diseases, safety, non-toxicity, good stability and long term preservation. The invention also relates to a use of the Lactobacillus crispatus 262-1 in medicines for preventing and / or treating the gynecological diseases.

The present invention relates to a pharmaceutical formulation for stimulating the growth of gram-positive bacilli and increasing the acidity in the vagina which comprises sucrose and / or maltose, to the use of certain sucrose and / or maltose, in preparing the pharmaceutical formulation for stimulating the growth of gram-positive bacilli and increasing the acidity in the vagina, in particular to a method for stimulating the growth of gram-positive bacilli and increasing the acidity in the vagina, treating the reduction of gram-positive bacilli and the lowness of acidity in vagina as well as the vaginitis and the disturbance of vaginal bacterioflora accompanying the reduction of gram-positive bacilli, especially bacterial vaginal disease.< / PTEXT>

The present invention relates to one kind of mangiferin-berberine composition with relatively high water solubility and its preparation process and medicinal application. The mangiferin-berberine composition has water solubility up to 25 mg / ml. Animal test shows that the mangiferin-berberine composition has functions of inhibiting bacteria, lowering blood sugar, diminishing inflammation, protecting liver, etc. The mangiferin-berberine composition may be used in preparing eye drops, medicine for women's vaginal diseases, medicine for lowering blood sugar and medicine for treating hepatitis.

The invention discloses a gynecological lotion and a preparation method thereof. The gynecological lotion contains the active ingredients of raw materials by weight parts: 2-3 of cloves, 3-5 of pepper, 10-15 of cnidium, 3-5 of mint, 10-15 of salvia, 7-9 of radixstemonae, 10-15 of smilax, 5-8 of white moss leather, 7-9 of sophora, 4-6 of Phellodendron, 3-5 of polygonum cuspidate, 4-6 of dandelion, 3-5 of berberine, 10-15 of fructuskochiae and 0.1-0.3 of borneol. The novel gynecological lotion consists of over ten Chinese herbs, has reasonable component prescription compatibility, can obviously reduce the number of vaginal disease-causing micro-organisms and the infection chances, and has more prominent effects of bacterial, fungal and trichomonas vaginitis caused by common micro-organisms.

The invention provides lactobacillus gasseri and application thereof for preparing vaginal bacteriostatic drugs. The lactobacillus gasseri is collected in China General Microbiological Culture Collection Center, and has a collection number of CGMCC No. 14109. Study of metabolic performance of the lactobacillus gasseri discovers that, compared with ordinary lactobacillus gasseri, the strain has high lactic acid and hydrogen peroxide production capacity, is excellent in bacteriostatic ability of pathogenic bacteria, and also has outstanding vaginal epithelial cell adhesion ability. Based on theprevious discovered novel properties, the invention further provides application of the lactobacillus gasseri in preparation of vaginal bacteriostatic drugs, so that treatment of multiple bacterial vaginal diseases can be realized. The bacterium agent disclosed by the invention has obvious effects on the bacterial vaginal diseases and is safe, non-toxic, excellent in stability and capable of beingpreserved for a long time. The invention further relates to application of the lactobacillus gasseri in medicines for preventing and / or treating gynecological diseases.

The invention provides an externally-used pharmaceutical composition for vaginal sanitation and treating gynaecologic diseases and its preparing process, wherein the medicament is prepared from bee glue extract, oil of aromatic turmeric, alkanna tinctoria extract and purple perilla seed as raw material through steps of supercritical CO2 separation and abstraction, molecular distillation, low-temperature sterilization and centrifugation, sound film separation. The medicament can be made into bottle-packed preparations or soft capsules.

The invention provides the reagent box checking the bacterial vaginal disease, it includes the dry chemic reacting setting, the diluent and the liquid showing the color; the reacting setting has three blind holes placed the reagent mat testing the chroma of excessive oxidation hydrogen, the chroma of the leucocyte ester enzyme and the active ability of the saliva acid enzyme; the regent mat testing the chroma of the excessive oxidation hydrogen is dipped in the enzyme solution containing the peroxide enzyme, the phosphate amoritizing liquid, the 4-amino antipyrine, the 3,5-double chlorine double hydroxide group dobesilate and the vitamin C and dried. The reagent mat testing the chroma of the leucocyte ester enzyme is dipped in the enzyme solution containing the 5 bromine-4 chlorin- 3 heteroauxing salt and the cane suger and is dried; the reagent mat testing the active ability of the saliva acid enzyme is dipped in the 5 bromine-4 chlorin-3 indloe nerve arginine salt, the acetic acid salt cushioning liquid and the fucose and is dried; the cushioning liquid is composed of the physiological brine and MES cushioning liquid; the liquid showing the color is the B solution fixing the purple. The entironment, the cleanliness of the procreating path of the checked and the condition of the bug inducing the bacterial vagina can be test at the same time; it has many merits such as the easy handling, the celerity and the cheap cost.

The present invention relates to a pH test glove bearing a reporter substance indicating the possible presence of vaginal affection. such as infections, in particular bacterial vaginosis, or vaginitis. This glove is easy to use, accurate and safe for the woman using it. The present invention also provides packages comprising the glove and gynecological compositions for treating vaginal affections

A method for application of natural vaginal flora transplantation in treating gynecological inflammation is characterized in that feminine dysbacteriosis is recovered by means of the opsonization of normal feminine vagina probiotics florae on feminine vaginal diseases, so that the feminine urogenital tract health is maintained. The method is also characterized in that bacteria are used as an antibacterial agent, and the micro-ecology treatment method free of drug resistance and side effects is realized by maintaining the stability of feminine lower genital tract florae; the adopted preparation is a vaginal embolism which is easy to make, convenient to use and quite low in cost.

The invention provides lactobacillus rhamnosus and application thereof to preparation of a vaginal antibacterial medicine. The lactobacillus rhamnosus is preserved in China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.14184. According to research on the metabolic performance of the lactobacillus rhamnosus, compared with the common lactobacillusrhamnosus, the lactobacillus rhamnosus has higher production capacity of lactic acid and hydrogen peroxide, has higher antibacterial capability on pathogenic bacteria and has prominent vagina epithelial cell adhesion capacity. Based on the above discovered new performance, the new application of the lactobacillus rhamnosus to preparation of the vaginal antibacterial medicine is determined, and various bacterial vaginal diseases can be treated. The lactobacillus rhamnosus has remarkable effect on the bacterial vaginal diseases, is safe, non-toxic and high in stability and can be stored for a long time. The invention also relates to application of the lactobacillus rhamnosus to medicines for preventing and / or treating gynecological diseases.

The invention provides lactobacillus reuteri and an application of the lactobacillus reuteri in preparing a vaginal antibacterial drug. The lactobacillus reuteri is collected in China General Microbiological Culture Collection Center with a collection number of CGMCC No. (China General Microbiological Culture Collection Center number) 14110. A study of metabolic performance of the lactobacillus reuteri finds that the strain has better lactic acid production capacity, very strong hydrogen peroxide generation capacity, very strong antibacterial capacity on pathogenic bacteria and excellent vaginal epithelial cell adhesive capacity compared with the common lactobacillus reuteri. Based on the above novel properties found, the novel application of the lactobacillus reuteri in preparing the vaginal antibacterial drug is determined, and treatment of multiple bacterial vaginal diseases can be achieved. The lactobacillus reuteri has a significant effect on the bacterial vaginal diseases, is safe, nontoxic and good in stability and can be stored for a long term. The invention further relates to an application of the lactobacillus reuteri in drugs for preventing and / or treating gynecological diseases.

The invention discloses lactobacillus curvatus and pharmaceutical application thereof. The lactobacillus curvatus provided by the invention specifically is lactobacillus curvatus IMC-79 which has a relatively strong capability of generating H2O2 and can effectively inhibit the growth of external pathogenic bacteria and other conditioned pathogens; and meanwhile, the lactobacillus curvatus IMC-79 also has a relatively strong effect of adhering vaginal epithelial cells to ensure that a strain is fixedly planted on the vaginal epithelium. The lactobacillus curvatus IMC-79 provided by the invention has a certain application prospect in the aspect of preventing and treating bacterial vaginal diseases.

A therapeutic composition for vaginal administration based on the generation of a biocidal anion by an enzymatic reaction catalyzed by a peroxidase. The peroxide utilized by the peroxidase enzyme can be endogenous or can be generated by the action of an oxidase enzyme on a suitable substrate. Therapeutic compositions according to the present invention are useful for the treatment of vaginal diseases and conditions, including bacterial and fungal infections.

The present invention relates to a pharmaceutical formulation for stimulating the growth of gram-positive bacilli and increasing the acidity in the vagina which comprises sucrose and / to maltose, to the use of certain sucrose and / or maltose, in preparing the pharmaceutical formulation for stimulating the growth of gram-positive bacilli and increasing the acidity in the vagina, in particular to a method of stimulating the growth of gram-positive bacilli and increasing the acidity in the vagina, treating the reduction of gram-positive bacilli and the lowness of acidity in vagina as well as the vaginitis and the disturbance of vaginal bacterioflora accompanying the reduction of gram-positive bacilli, especially bacterial vaginal disease.

The invention discloses a female genital cleaning and care solution. The female genital cleaning and care solution is prepared from the following components: 10 to 15 parts of chitosan quaternary ammonium salt hydrogel, 10 to 25 parts of itching stopping agent, 6 to 12 parts of inorganic nano antibacterial agent, 4 to 7 parts of nano lecithin and 20 to 35 parts of auxiliary agent. The cleaning andcare solution disclosed by the invention can be used for absorbing tissue fluid oozed from skin with inflammations and also can have remarkable antibacterial, anti-inflammation and repairing-promoting effects; the cleaning and care solution is easily absorbed in a percutaneous manner through an external bathing manner and genitals keep clean and sanitary; the cleaning and care solution also can be used for preventing and treating genital flora imbalance and reducing the risk of bacterial genital diseases; the multi-effects of cleaning, nutrition, sterilization and care are realized.

The invention discloses a pharmaceutical composition for treating vaginopathy which comprises the following raw material medicinal materials (by weight proportion): yellow corktree bark 200-600 parts, rheum officinale 200-600 parts, red sage root 200-600 parts, frank incense 60-120 parts, myrrh 60-120g, alkanna tinctoria 200-600 parts, gecko powder 100-300 parts and borneol 10-30 parts.

The invention discloses a vaginal fluid detection kit, which comprises a reaction device and a color developing agent, wherein the reaction device comprises a reaction hole for detecting beta-glucuronidase, a reaction hole for detecting acetylglucosaminidase, a reaction hole for detecting coagulase and a reaction hole for detecting proline aminopeptidase; when the kit is used for detecting vaginal secretion, the used diluent is normal saline. The vaginal secretion detection kit has the advantage that pathogenic bacteria or pathogens of bacterial vaginal diseases and trichomonas vaginitis can be used for assisting in the fast judgment of the vaginal disease condition. The invention also discloses a preparation method of the vaginal secretion detection kit.

The invention discloses a method for application of artificially-cultured vaginal flora transplantation in treating gynecological inflammation. According to the method, feminine dysbacteriosis is recovered by means of the opsonization of normal feminine vagina probiotics florae on feminine vaginal diseases, so that the feminine urogenital tract health is maintained. The method is characterized in that bacteria are used as an antibacterial agent, and the micro-ecology treatment method free of drug resistance and side effects is realized by maintaining the stability of feminine lower genital tract florae; the adopted preparation is a vaginal embolism which is easy to make, convenient to use and quite low in cost.

The invention discloses a medicine for treating vagina disease using biologic alive bacterium, which is made from: 15-35 weight parts of oligomerization isomaltose, 5-15 weight parts of amylaceum, and 2-5 hundred millions CFU per gram of lactobacillus delbriickii based on the total weight of the fore-mentioned two substances. The invention further discloses the preparing method of the medicine. Comparing with the traditional chemical medicine, the invention achieves the following advantages of safety in using, no poison, no harm, no irritability, high curative ratio, hardly recurrence, no drug tolerance, small single dose, rapid effect and using convenience by treating vagina disease using micro ecology theory.

The invention discloses a detection reagent card and a kit and relates to the technical field of disease detection reagents. The detection reagent card disclosed by the invention is provided with a detection groove capable of detecting neuraminidase, catalase, leucocyte esterase or a pH (Potential of Hydrogen) value index. The invention further provides a bacterial vaginal disease multi-index self-detection kit comprising the detection card and a self-heating pad. The detection of each index of the reagent card disclosed by the invention is mutually independent and is one-step reaction; an additional developing solution or stopping solution is not needed; a subject only needs to add collected vaginal secretion into the reagent card and can detect the vaginal discharge; the self-heating padis introduced into the kit and heating equipment does not need to be additionally arranged, so that detection conditions are greatly widened and the reagent card is convenient for the subjects to useat home; domestic popularization of bacterial vaginosis detection is facilitated.

The invention discloses a rigid microwave vaginoscope system used for treating common gynecopathy, belonging to the field of medical equipment. The rigid microwave vaginoscope system comprises a rigid vaginoscope and a cold light source main machine, a main camera and a monitor which are connected with the rigid vaginoscope, and the rigid vaginoscope is also provided with a microwave knife operating device used for cooperating with treatment and a micro knife system main machine used for cooperating with the microwave knife operating device. The rigid microwave vaginoscope system comprises a separating type and an integral type. As a new type medical treatment means for treating various diseases by using microwave energy for local heating, the microwave technology has wide application range, obvious curative effect, safety and no side effect. In the invention, the vaginoscope technology is organically combined with the microwave technology and serves gynecilogical operation by virtue of the characteristics of smooth incision, less bleeding and difficult infection of the microwave knife, and the diagnosis of the vaginoscope and the therapeutic action of microwave are superposed, and the cure rate and the accuracy of the operation can be increased to achieve the purpose of reducing recurrence rate. The invention can improve the medical quality and the medical safety and better overcome the defects of the traditional operation for treating vaginal diseases, thereby obtaining unexpected results.

The invention discloses a Lactobacillus crispatus 262-1 and its application in gynecological diseases. The Lactobacillus crispatus 262-1 is a new Lactobacillus crispatus strain, and has a preservation number of CGMCCNo.6469 in China General Microbiological Culture Collection Center. The Lactobacillus crispatus 262-1 has the advantages of strong acid and H2O2 production ability, strong adherence to vaginal epithelial cells, substantial resistance on bacterial vaginal diseases and various vaginal gynecological diseases, safety, non-toxicity, good stability and long term preservation. The invention also relates to a use of the Lactobacillus crispatus 262-1 in medicines for preventing and / or treating the gynecological diseases.

The invention relates to a capsule for treating women's vaginal diseases, as well as the preparing process, wherein the capsule comprises contents and hard shells, the contents include oil of aromatic turmeric, borneo camphor and auxiliary materials.

The invention provides a disposable vaginal dilator. The disposable vaginal dilator comprises an upper dilation sheet and a lower dilation sheet, wherein the upper dilation sheet is hinged to the lower dilation sheet; the upper dilation sheet comprises an upper wing and a push rod, and the push rod is integrally connected with the upper wing; an inspection hole is formed in the upper dilation sheet; the lower dilation sheet comprises a lower wing, a lower handle and a positioning rod, the lower handle is integrally connected with the lower wing, and the positioning rod is fixedly arranged on the lower handle; clamping teeth I are arranged on the side surface of the push rod, and a plurality of clamping teeth II are arranged on the side surface of the positioning rod and are buckled with the clamping teeth I. The disposable vaginal dilator has the advantages that by utilizing the principle that the clamping teeth I on the push rod can only be slide along the clamping teeth II on the positioning rod in a unidirectional way, the clamping teeth I and the clamping teeth II are respectively arranged on the side surfaces, the separating and buckling are controlled by the self elasticity of the material, and the dilation and fixation can be completed by one hand; when the dilation sheet is opened, the failure to opening due to overlarge elasticity of the push rod is avoided, the error produced in the cervix uteri or vaginal disease measuring process is reduced, and the measuring accuracy of data is guaranteed.

The invention relates to a method for preparing control-release paste medium, comprising cyclodextrin, drug, macromolecule and elasticizer. The invention uses package and macromolecule mixing technique to prepare the control-release paste medium with needed rigidity and rheological property. The invention is characterized in that it uses insoluble cellulose ethyl ether and low-permeability acrylic resin mixture medium as the skeleton control-release material, and uses cyclodextrin and ealsticizer to adjust the rheological property and drug release speed of the paste, uses glycerin and drug grind method to pack the drug. Via external release degree test, the paste which contains Minocycline Hydrochloride, polycyclic acid or the like, via slurry method (at 37Deg. C, 100rpm) can reach 20-40% in 1h, 40-60% in 3h, 50-80% in 7h, and 80-90% in 12h. The inventive paste can be used to treat mouth and vaginal diseases.

A hygienic plug prepared by activated carbon fibre with absorption to target direction has 70-95 wt.% of C content in activated carbon fibre, specific surface area of 700-1500 m2 / g and pore volume of equal or bigger than 0.45ml / g. It can be used to cure women's vaginal disease.

The invention discloses a composition composed of three kinds of lactobacillus. The composition contains a lactobacillus rhamnosus strain, a lactobacillus gasseri strain and a lactobacillus jensenii strain, and can resist bacterial vaginosis and related vaginal infection. The composition has a remarkable effect on the bacterial vaginosis and related vaginal diseases, is safe and non-toxic, has good stability, and can be stored for a long time. Compared with other commercially available preparations at present, the strains in the composition can be effectively planted, and the three kinds of lactobacillus strains can play a synergistic role; and compared with a single strain preparation, the composition composed of the three kinds of lactobacillus has the advantage that vaginal microecologycan be formed more obviously.

The invention discloses a vaginal speculum which comprises an upper duck-mouth sheet and a lower duck-mouth sheet which are connected in a hinged mode, a camera, a display and a control system. The back end of the lower duck-mouth sheet is provided with a hollow handle, the inner side wall of the lower duck-mouth sheet is provided with a protrusion which extends along the lower duck-mouth sheet to the inner side wall of the handle, a cavity is formed in the protrusion, one end of the cavity is open, the other end of the cavity is closed, the closed end of the cavity is located in the lower duck-mouth sheet, and the opening end of the cavity is located in the handle; the camera is located in the closed end of the cavity, and the control system is connected with the camera and the display. The vaginal speculum has the advantages that through the existing mature camera with a light source and a visible system, a doctor does not need to move close to the vaginal speculum to perform close diagnosis and treatment on vaginal diseases of women, and the health and safety of the doctor is guaranteed; meanwhile, a bright diagnosis and treatment environment with the larger viewing angle is achieved, therefore, no dead zone exists in vaginal disease diagnosis and treatment, and the doctor can conveniently and clearly observe a diseased part to perform symptomatic diagnosis and treatment.