810 results about "Streptococcus" patented technology

The invention discloses a SnO2 / SnS2 / AgS nano material with piezoelectric electro-catalytic tooth whitening and sterilizing performance and a preparation method and application thereof, and the preparation method comprises the following steps: (1) dripping a silver nitrate aqueous solution into a prepared SnO2 / SnS2 nano material aqueous dispersion, carrying out hydro-thermal treatment for 2 hours, centrifuging, washing and drying to obtain a SnO2 / SnS2 / Ag2S ternary semiconductor heterojunction nano material; (2) food indigo is adopted to simulate tooth surface pigments, piezoelectric electro-catalytic degradation is carried out by using the SnO2 / SnS2 / Ag2S ternary semiconductor heterojunction nanomaterial, and the pigment degradation efficiency can reach 95% or above; (3) the SnO2 / SnS2 / Ag2S heterojunction nanomaterial is used for piezoelectric electro-catalysis treatment of the streptococcus mutans pellicle, and the antibacterial rate of the pellicle can reach 90% or above; and (4) compared with a 3% H2O2 aqueous solution for treating the enamel surface structure, the SnO2 / SnS2 / Ag2S nano-material piezoelectric electro-catalysis treatment of teeth has small damage to the enamel surface structure. According to the invention, more nano materials with tooth whitening and sterilizing performance and the preparation method thereof are provided, so that the problems of single variety, single preparation method, low electron-hole separation efficiency and large side effect of the existing tooth whitening and sterilizing nano materials are solved.

The invention provides a preparation method and application of casei paracasei IOB413 after-generation powder, and relates to the field of microorganisms. Tartary buckwheat is used as a solid-state fermentation culture medium, and the lactobacillus paracasei IOB413 is fermented and then crushed to prepare the lactobacillus paracasei IOB413 after-generation powder with high flavone content. The flavonoid content of the metagenic powder prepared by the method is far higher than that in tartary buckwheat and casei paracasei IOB413, the levels of tumor necrosis factor alpha (TNF-alpha) and interleukin (IL-6) can be reduced, the level of anti-inflammatory factor interleukin (IL-10) can be increased, the gingival index and the dental plaque index can be reduced, the growth of streptococcus mutans can be inhibited to a certain extent, and the metagenic powder can be used for preventing and treating the dental plaque. The oral micro-ecology is improved.

The present invention discloses a mutant strain of Streptomyces parvum and its application in producing glutathione, belonging to the field of genetic engineering. The present invention successfully constructs a mutant strain of Streptomyces parvum by overexpressing the glnA gene in Streptomyces parvum; wherein the nucleotide sequence of the glnA gene is shown in SEQ ID NO: 1. Experiments have shown that compared with the wild-type Streptomyces parvum, the mutant strain of Streptomyces parvum can significantly increase the content of glutathione and glucose in the fermentation product, and can also improve the utilization efficiency of ammonia nitrogen during the fermentation process. The present invention provides new strain resources and methods for mass production of bacterial-derived glutathione, and provides new agricultural antibiotic resources and strategies for preventing and controlling a variety of plant diseases.

The invention relates to the technical field of microorganisms, in particular to a viable bacterium preparation of a lactobacillus paracasei strain as well as a preparation method and application of the viable bacterium preparation. The viable bacterium preparation comprises a lactobacillus paracasei strain and auxiliary materials, and the preservation number of the lactobacillus paracasei strain is CGMCC (China General Microbiological Culture Collection Center) No.27974. The viable bacterium preparation can inhibit the growth of streptococcus mutans, reduce the formation of a dental plaque biofilm caused by the streptococcus mutans, reduce the content of a mature dental plaque biofilm, inhibit the level of water-insoluble exopolysaccharides generated by the streptococcus mutans, reduce the expression quantity of cariogenic genes gtfB, gtfC, gtfD, ftf and LuxS of the streptococcus mutans, improve the cariogenic activity of the streptococcus mutans and improve the cariogenic activity of the streptococcus mutans. The adhesion rate of streptococcus mutans on a hydroxyapatite tooth model is reduced, and a beneficial in-vitro probiotic function is achieved.

The invention relates to the technical field of gene engineering, in particular to a nucleic acid composition, a kit and a detection method for simultaneously and rapidly detecting 16 respiratory tract pathogens. The method specifically comprises the following steps: detecting influenza A virus, influenza B virus, novel coronavirus (ORF1ab gene, N gene), haemophilus influenzae, universal human parainfluenza virus, respiratory syncytial virus, human metapneumovirus, enterovirus, mycoplasma pneumoniae, group A streptococcus, bordetella pertussis, common coronavirus, rhinovirus, bocavirus and adenovirus; a forward primer, a reverse primer and a specific fluorescent probe of streptococcus pneumoniae. Through the PCR reaction, whether respiratory tract pathogens exist or not can be rapidly detected from a specimen at the same time, typing identification of 16 respiratory tract pathogens is carried out at the same time, and compared with a single fluorescent quantitative PCR method, the method is more convenient and rapid, and the cost is lower.

The invention discloses an antibacterial peptide SAMP4 or a derivative thereof, a pharmaceutical composition and application, and belongs to the technical field of biology, the amino acid sequence of the antibacterial peptide SAMP4 is as shown in SEQ ID NO: 1, and the antibacterial peptide SAMP4 has a broad-spectrum antibacterial effect and can be used for preparing antibacterial peptide SAMP4. The compound has a strong bacteriostatic effect on various gram-positive bacteria such as staphylococcus aureus, enterococcus and streptococcus and various gram-negative bacteria such as escherichia coli, acinetobacter baumannii and pseudomonas aeruginosa, and is strong in antibacterial activity, wide in antibacterial spectrum and low in toxicity. The invention also provides a derivative and a salt of the antibacterial peptide SAMP4 and application of the antibacterial peptide SAMP4 and the derivative and the salt of the antibacterial peptide SAMP4 to research, development and preparation of various antibacterial products or / and antibacterial drugs and treatment of bacterial infectious diseases, and the antibacterial peptide SAMP4 and the derivative and the salt of the antibacterial peptide SAMP4 are remarkable in advantages and wide in application prospect.

The invention discloses a lactobacillus delbrueckii subsp. Lactis TG001 and application thereof in improving oral health, and belongs to the technical field of probiotic application, the preservation number of the lactobacillus delbrueckii subsp. Lactis TG001 is CCTCC NO: M 20241941, the preservation place is China Center for Type Culture Collection in Wuhan, and the preservation date is September 9, 2024. The lactobacillus delbrueckii subsp. Lactis TG001 has a good inhibition effect on common oral pathogens such as streptococcus mutans and porphyromonas gingivalis, particularly can inhibit the growth of cariogenic bacteria streptococcus mutans by generating hydrogen peroxide and remove biofilm formation, and has good tolerance to antibacterial substances in an oral environment. Therefore, the oral cavity diseases such as dental caries, periodontitis and ozostomia can be prevented, the micro-ecological environment of the oral cavity is effectively improved, meanwhile, the peculiar smell of the oral cavity is relieved, and good application prospects are achieved in preparation of products for preventing and / or treating the oral cavity diseases such as dental caries and periodontitis.

The invention provides a nucleic acid composition for respiratory tract pathogen detection and application thereof, and relates to the technical field of biology. The invention provides a nucleic acid detection composition which has high specificity and can be used for detecting various respiratory pathogens. The composition can be used for detecting influenza B virus, influenza A virus H1N1, influenza A virus H3N2, novel coronavirus N gene, novel coronavirus O gene, respiratory syncytial virus, I-type parainfluenza virus, II-type parainfluenza virus, III-type parainfluenza virus, IV-type parainfluenza virus, rhinovirus, adenovirus, haemophilus influenzae, and the like. The kit has 15 pathogens including streptococcus pneumoniae and staphylococcus aureus, the lower detection limit can be as low as 20 copies / reaction, and the kit plays an important role in rapid detection of respiratory tract pathogens.

The invention relates to a preparation method of a tricholoma matsutake fermentation product with anti-wrinkle and firming effects as well as a product and application of the tricholoma matsutake fermentation product. The preparation method comprises the following steps: mixing a composite plant extract, a carbon source, inorganic salt and water, then sterilizing to obtain a sterilized culture medium, inoculating a composite probiotic agent into the medium, and carrying out fermentation culture to obtain the tricholoma matsutake fermentation product with anti-wrinkle and firming effects. Centrifuging, filtering and sterilizing the culture product to obtain a tricholoma matsutake fermentation product; the bacterial strains in the compound probiotic agent comprise a combination of streptococcus thermophilus, a lactobacillus paracasei YK-L003 bacterial strain and a saccharomyces cerevisiae YK-S001 bacterial strain. According to the invention, specific strains are subjected to compounding and combined fermentation, and the fermentation product filtrate obtained after fermentation treatment of the three strains has an excellent skin conditioning effect, can effectively improve the skin state and resist and weaken wrinkles, and has an excellent effect when being applied to moisturizing and anti-wrinkle cosmetics.

The invention discloses a composition for treating insomnia. Comprising probiotic compounds: lactobacillus plantarum, bifidobacterium lactis, lactobacillus crispatus, lactobacillus acidophilus, lactobacillus rhamnosus, bifidobacterium bifidum, lactobacillus reuteri, lactobacillus casei, lactobacillus bulgaricus, lactobacillus fermentum, lactobacillus gasseri, lactococcus lactis, bifidobacterium longum, lactobacillus salivarius, bifidobacterium breve, streptococcus thermophilus and lactobacillus paracasei; lactobacillus helveticus; and traditional Chinese medicine components and prebiotics. Probiotics are matched with traditional Chinese medicines with homology of medicine and food, and corresponding prebiotics are supplemented, so that the balance of intestinal flora can be adjusted and information transmission between intestines and cranial nerves can be promoted through the synergistic effect of the probiotics and the corresponding prebiotics, and then gastrointestinal inflammation, ulcer, helicobacter pylori infection, constipation and insomnia are treated or improved; and treating or improving spleen and stomach disharmony, liver qi stagnation, excessive heart fire, fire excess from yin deficiency, heart-kidney disharmony caused by emotion, pressure, diseases and the like, and insomnia caused by the symptoms.

The invention relates to a plant lactobacillus with hypoglycemic ability, and an application, a product and a method thereof, and belongs to the technical field of microorganisms. The invention provides a lactobacillus plantarum strain Lp116 with the capability of reducing blood sugar, and the preservation number of the lactobacillus plantarum strain Lp116 is CCTCC (China Center for Type Culture Collection) NO: M 20241784. The invention also provides an application of the strain Lp116 in preparation of hypoglycemic drugs or health-care foods with an auxiliary hypoglycemic function or bacteriostatic agents or non-treatment-destination bacteriostasis, and a product and a method based on the strain Lp116. The strain Lp116 disclosed by the invention has a relatively strong inhibition effect on escherichia coli, staphylococcus aureus, salmonella, streptococcus pharyngobuccal inflammation and streptococcus pseudopneumoniae, and can effectively achieve the effects of reducing blood sugar and regulating intestinal flora.

Provided herein is a pleuromutilin derivative containing a cycloalkyl group and preparation method and application thereof. Specifically, the pleuromutilin is reacted with p-toluenesulfonyl chloride to obtain an intermediate I, and the intermediate I is reacted with 1-amino-2-methylpropane-2-thiol hydrochloride to obtain an intermediate II, and then the intermediate II is reacted with cycloalkylcarbonyl chloride to obtain a target derivative. The synthesis process of these derivatives is simple, with a high yield and simple purification. These derivatives can effectively inhibit activities of Staphylococcus aureus and Streptococcus, and have superior activities to the marketed Tiamulin, and they also have good antibacterial activities against drug-resistant bacteria. In particular, the treatment effect of the derivative 2 of the target derivative is significantly superior to the clinical drugs Tiamulin and Valnemulin. They are suitable as new antibacterial drugs for prevention and treatment of infectious diseases caused by bacteria in humans or animals.

The present invention relates to the screening of functional probiotics and its application, and specifically provides a strain of Lactobacillus casei RH99 that produces high extracellular polysaccharides and relieves vaginitis, and its preservation number is CGMCC No.32108. The Lactobacillus casei can inhibit the growth of Gardnerella, Candida albicans, and Peptostreptococcus and their biofilm generation ability; the extracellular polysaccharides produced by it have a significant promoting effect on the biofilm formation of Lactobacillus casei itself. RH99 is inoculated into the vagina, and its strain, the metabolites (exocellular polysaccharides) produced, and the core monosaccharide (D-mannitol) can all inhibit the colonization of pathogenic bacteria and promote the colonization of lactic acid bacteria; and RH99 can also relieve vaginitis by inhibiting inflammatory factors. It can be seen that RH99 can inhibit the growth of pathogenic bacteria + inhibit biofilm formation + inhibit pathogenic bacteria adhesion + inhibit the level of inflammatory factors through key core metabolites, and realize the all-round inhibition of four-in-one.

The invention provides cheese and a preparation method thereof, and the preparation method comprises the following steps: carrying out first fermentation on a base material containing raw milk in the presence of a basic leavening agent, and inactivating the basic leavening agent to obtain a first fermentation system; wherein the basic leavening agent comprises lactobacillus bulgaricus and / or streptococcus thermophilus; and carrying out second fermentation on the first fermentation system in the presence of medium-temperature bacteria to obtain the cheese. The method can shorten the fermentation time and improve the cheese production efficiency.

The invention relates to a preparation method of a rice leavening with a scalp care effect and a product and application thereof, the preparation method comprises the following steps: mixing a rice raw material, a plant raw material, water, a magnesium salt, a sodium salt and Tween, sterilizing to obtain a fermentation medium, inoculating a compound microbial agent into the fermentation medium, and fermenting to obtain the rice leavening with the scalp care effect. After the fermentation liquid is finished, sterilizing and filtering to obtain a rice leavening; wherein the compound microbial agent comprises a first microbial strain and a second microbial strain; the strains in the first microbial strain comprise a combination of streptococcus thermophilus, bifidobacterium breve and a plant lactobacillus YK-L002 strain; and the second microbial strain comprises a trichosporon YK-S004 strain. According to the invention, specific strains are subjected to compounding and combined fermentation, and the fermentation product filtrate obtained after fermentation treatment of four bacteria has excellent hair care and nourishing effects, and can effectively condition the scalp micro-ecological environment and nourish the hair quality.

The invention relates to plant fermented oil for cosmetics and a preparation method of the plant fermented oil. The preparation method comprises the following steps: S1, fungus cultivation; s2, fungus selection: respectively taking single colonies of the cultured escherichia coli, staphylococcus aureus, lactobacillus lactis and streptococcus lactis; s3, bacteriostatic concentration selection: adding mixtures of cortex albiziae oil and schisandra chinensis oil with different concentrations, detecting the survival rate of the fungi, and recording the concentration with the lowest survival rate of the fungi; s4, performing fermentation; and S5, post-processing. On the basis of fermentation of conventional vegetable oil, a mixture of cortex albiziae oil and fructus schizandrae oil is added, so that the fermentation time of the plant fermentation oil is shortened to a certain extent compared with the traditional fermentation time, and the fermentation efficiency is greatly improved; moreover, the fermented oil can keep better antibacterial activity at a lower temperature, so that the phenomena of low activity and uncontrollable product of the fermented vegetable oil caused by high-temperature sterilization are avoided.

The invention relates to a skin-cleaning composition and application thereof in cleaning cream, and belongs to the technical field of daily chemicals, the skin-cleaning composition comprises the following raw materials: plant fermentation liquor, a chrysanthemum artemisia extract, silk amino acid, cetyl alcohol ethyl hexanoate, PEG-20 glyceryl triisostearate and soapberry seed oil; the preparation method of the plant fermentation liquid comprises the following steps: S1, pretreating part of the raw materials; s2, activating and culturing the strain; and S3, adjusting the pH value of the mixed solution A, performing temperature-controlled sterilization, cooling, adding mannase, performing temperature-controlled enzymolysis, performing enzyme deactivation after enzymolysis is completed, so as to obtain a mixed solution B, cooling, adding a lactobacillus acidophilus fermentation seed solution and a streptococcus thermophilus fermentation seed solution, performing temperature-controlled standing fermentation, performing temperature-controlled sterilization and speed-controlled centrifugation after fermentation is completed, taking supernate, and performing 0.22 mu m membrane microfiltration, so as to obtain the plant fermentation liquor. The raw materials of the skin-cleaning composition provided by the invention have a synergistic effect, so that the skin-cleaning composition has the effects of moisturizing and whitening while effectively cleaning the skin.

The invention provides a probiotic composition for preventing and / or inhibiting oral pathogens as well as a derivative product, a preparation method and application of the probiotic composition, and belongs to the technical field of oral care. The probiotic composition comprises the following bacterial strains in parts by mass: 90 to 0.45 part of a lactobacillus rhamnosus bacterial strain A2114, 10 to 0.3 part of a plant lactobacillus bacterial strain A2124, 80 to 0.4 part of a pediococcus pentosaceus bacterial strain A2135, 250 to 0.25 part of a lactobacillus reuteri bacterial strain A21350, and 40 to 0.2 part of a plant lactobacillus bacterial strain A2109. The probiotic composition or the metabolite thereof can effectively inhibit oral pathogens such as streptococcus mutans, porphyromonas gingivalis, helicobacter pylori, escherichia coli and staphylococcus aureus. Therefore, the probiotic composition or the metabolite thereof shows a good application prospect in the aspects of preventing and relieving oral problems such as decayed teeth, periodontitis and ozostomia.

The invention belongs to the technical field of biological medicines, and relates to streptococcus thermophilus with a rare ginsenoside conversion effect and application of the streptococcus thermophilus. The strain is Streptococcus thermophilus 17140, the Streptococcus thermophilus 17140 is preserved in the Guangdong Microbial Culture Collection Center (GDMCC) on September 23, 2024, and the preservation number of the Streptococcus thermophilus 17140 is GDMCC NO.65173. The invention further discloses a preparation method of the Streptococcus thermophilus 17140. The strain disclosed by the invention has good functions of fermenting and converting various ginsenosides and notoginsenoside and generating rare ginsenosides.

The invention provides an Auricularia auricula polysaccharide, its application and preparation method thereof, which belong to the technical field of improving polysaccharide. After being degreased, the Auricularia auricula is subjected to preliminary enzymolysis under the effect of helicase, is further subjected to deep enzymolysis under the effect of complex enzyme through synergetic ultrasound-assisted degradation and extraction with H2O2, and is subjected to mixed fermentation by Lactobacillus bulgaricus, Streptococcus thermophilus and Bifidobacterium longum, the obtained fermented Auricularia auricula polysaccharide is subjected to a phosphorylation reaction under the effect of a phosphorylation reagent, and after further deproteinization and decolorization, the obtained fermented Auricularia auricula polysaccharide is chelated with zinc salt to obtain a polysaccharide-zinc compound, and the amount of the extracted Auricularia auricula polysaccharide is improved. The finished product of the invention has the effects of reducing blood sugar and blood fat, regulating total cholesterol and effectively improving HDL cholesterol.

The invention belongs to the technical field of microorganism mutation breeding, and particularly relates to a nisin high-yield mutant strain with enhanced production performance. The mutant strain is specifically lactococcus lactis 2686, and the preservation number of the mutant strain is CCTCC (China Center for Type Culture Collection) NO: M 2023219. The strain has relatively high osmotic pressure tolerance, can still normally grow and produce nisin when the osmotic pressure is higher than 0.66 osM / kg H2O, meanwhile, the strain has excellent nisin production capacity, the titer reaches 9834 IU / mL when the strain is fermented in a shake flask for 21 hours, and the titer reaches 21000 IU / mL when the strain is fermented in a fermentation tank for 22 hours. The method is high in yield, good in stability, low in production cost and suitable for further industrial application.

The invention belongs to the technical field of probiotic particles, and particularly relates to probiotic particles for improving intestinal functions as well as a preparation method and application of the probiotic particles. The probiotic particles capable of improving the intestinal function comprise a probiotic core, a first embedding layer, a second embedding layer and a third embedding layer, the probiotic inner core is prepared from plant lactobacillus, bifidobacterium animalis, lactobacillus acidophilus, bifidobacterium longum, lactobacillus paracasei, lactobacillus rhamnosus, lactobacillus fermentum, lactobacillus helveticus, streptococcus thermophilus, plant lactobacillus, lactobacillus helveticus and lactobacillus rhamnosus. According to the present invention, the twelve probiotics are contained, and the latest three-layer embedding technology is adopted so as to enhance the storage property and the digestive tract tolerance, such that the product can maintain the beneficial bacterium activity for a long time without refrigeration, and the product is suitable for the crowd with the alteration of the intestinal flora.

The invention provides a Lactobacillus casei GG002, a bacteriocin solution of the Lactobacillus casei GG002, freeze-dried powder of the Lactobacillus casei GG002 and application of the bacteriocin solution and the freeze-dried powder of the Lactobacillus casei GG002 to treatment of oral ulcer, and belongs to the technical field of microorganisms. The invention finds that the lactobacillus casei GG002 can inhibit streptococcus mutans, fusobacterium nucleatum and porphyromonas gingivalis, and has the effect of treating oral ulcer. The invention further provides a bacteriocin solution, freeze-dried powder and metagen of the casei casei GG002, and the bacteriocin solution, the freeze-dried powder and the metagen can be used for effectively treating the oral ulcer.

The invention relates to the technical field of microbial identification, in particular to an identification method of a streptococcus thermophilus CICC 6063 strain and development and application of a strain level primer of the streptococcus thermophilus CICC 6063 strain. The invention provides an application of a nucleotide sequence as shown in SEQ ID NO: 1 in identification of a streptococcus thermophilus CICC 6063 strain. The invention provides an identification method of a streptococcus thermophilus CICC 6063 strain. The method comprises the following steps: extracting genome DNA of a to-be-detected strain, designing a primer aiming at a nucleotide sequence shown in SEQ ID NO: 1, amplifying the genome DNA, and judging whether the to-be-detected strain is the streptococcus thermophilus CICC 6063 strain or not by comparing the length of an actual amplification product with the length of a target amplification product and the condition of polymorphic site basic groups. The invention provides a simple and rapid method for identifying a streptococcus thermophilus CICC 6063 strain by utilizing a specific conserved gene sequence of streptococcus. The primer pair provided by the invention can be used for rapidly and accurately identifying the CICC 6063 strain on the strain level.

The invention discloses a strain of Planococcus rifitococcus 8-4 and application thereof, belongs to the field of microorganisms, and provides the Planococcus rifitococcus 8-4 with the preservation number of CGMCC (China General Microbiological Culture Collection Center) No.31311. The invention further discloses a preparation method of the Planococcus rifitococcus 8-4 and application of the Planococcus rifitococcus 8-4. The strain can tolerate 120 g / L of NaCl, and has potential plant growth promoting capabilities of producing IAA, forming a biological membrane and the like; the strain is inoculated to the rhizosphere of the potted tomato, and the growth index of the tomato can be improved under the stress of 450mM salinity. The strain can be used for preparing a functional microbial fertilizer, is used for enhancing the salt stress resistance of crops and improving the crop yield of saline-alkali soil, and has very important significance on improvement of the saline-alkali soil.

The invention discloses a streptococcus suis type 2 gene deletion strain as well as a construction method and application thereof, and belongs to the technical field of biological products. According to the invention, the B9H0105210 gene in the genome of the streptococcus suis serotype 2 SC19 is deleted in a homologous recombination manner for the first time, the hydrogen peroxide and nitric oxide stress resistance of the constructed streptococcus suis serotype 2 gene deleted strain is reduced, and the pathogenicity to mice is obviously weakened; moreover, the growth performance of the streptococcus suis type 2 gene-deleted strain is not greatly different from that of a wild strain SC19, the condition of gene recovery does not exist after continuous passage, and the streptococcus suis type 2 gene-deleted strain has an application prospect as an attenuated live vaccine, has a good immune protection effect on different genotypes of streptococcus suis such as the streptococcus suis type 2 strain SC19 and streptococcus suis type 2 P1 / 7, and has a good application prospect. And a certain cross immune protection performance is achieved.

The invention relates to a preparation method of a white truffle fermentation product with an anti-oxidation effect as well as a product and application of the white truffle fermentation product. The preparation method comprises the following steps: mixing a composite plant extract, inorganic salt, water and a composite probiotic agent for fermentation culture, and centrifuging, filtering and sterilizing a culture product to obtain the white truffle fermentation product, the strains in the compound probiotic agent comprise a combination of streptococcus thermophilus, saccharomyces cerevisiae boulardii, a plant lactobacillus YK-L002 strain and a saccharomyces cerevisiae YK-S001 strain. According to the invention, specific strains are subjected to compounding and combined fermentation, and the fermentation product filtrate obtained after fermentation treatment of four bacteria has an excellent skin conditioning effect, can effectively improve the skin state, significantly resist oxidation and resist and weaken wrinkles, and has an excellent effect when being applied to moisturizing and anti-oxidation cosmetics.

The invention relates to the technical field of microorganisms, in particular to an antibacterial bacillus subtilis subsp. Deserticola strain and application thereof.Bacillus subtilis subsp. Deserticola D7-HSJ9 is obtained from mangrove forest rhizosphere soil by the applicant, and it is detected that the strain has good salt resistance, alkali resistance and antibacterial characteristics, and the bacillus subtilis subsp. Deserticola D7-HSJ9 can be used as a bacillus subtilis subsp. Deserticola strain. According to the present invention, the bacterial strain has characteristics of good antibacterial effect, particularly good antibacterial effect on streptococcus iniae, and good antibacterial effect on a plurality of pathogenic bacteria such as photobacterium dama subspecies, aeromonas salmonicida, staphylococcus aureus and the like, such that the bacterial strain can effectively replace the antibiotic so as to improve the prevention and control of fish diseases, and a good germplasm resource is provided for later preparation of microecological preparation products.

The invention relates to the technical field of microorganisms, in particular to a lactobacillus paracasei strain as well as a fermentation product and application thereof. The preservation number of the lactobacillus paracasei strain is CGMCC (China General Microbiological Culture Collection Center) No.27974. The Lactobacillus paracasei can inhibit the growth of Streptococcus mutans, reduce the formation of a dental plaque biofilm caused by Streptococcus mutans, reduce the content of a mature dental plaque biofilm, inhibit the level of water-insoluble exopolysaccharides generated by Streptococcus mutans, and reduce the expression quantity of cariogenic genes gtfB, gtfC, gtfD, ftf and LuxS of Streptococcus mutans, and can be used for fermentation production of fermented milk. And oat milk and other fermentation products.

The invention belongs to the technical field of microorganisms, and relates to a strain of herbaspirillum as well as a fermentation method and application thereof. The invention provides a strain of brassica juncea, the brassica juncea is brassica juncea YLHb25.7, the brassica juncea is named as Herbaspiril huttiense, the brassica juncea is preserved in China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.35297. The invention also provides a preparation method of the brassica juncea. The herbispirillum sp. YLHb25.7 disclosed by the invention has the capabilities of producing ACC deaminase, producing IAA and fixing nitrogen, and has good drought resistance and saline-alkaline tolerance. The herbaspirillum sp. YLHb25.7 and the fermentation product thereof can promote the growth of wheat and corn, can be used as a microbial agent or bacterial fertilizer, and can be applied to the agricultural market.