4 results about "Streptococcus pyogenes" patented technology

This invention discloses a strain of Bifidobacterium animalis subspecies TRT-2A with allergy-relieving effects and its extracellular vesicle applications. The strain TRT-2A is deposited at the China Center for Type Culture Collection (CCTCC) on November 21, 2025, with accession number CCTCC NO:M 20252645. This strain is highly acid-resistant and exhibits good tolerance to artificial gastric and intestinal fluids. It effectively inhibits bacteria, particularly Streptococcus pyogenes, Streptococcus agalactiae, and / or Escherichia coli. Experimental results show that this strain can alleviate hormone-dependent dermatitis and effectively improve dermatitis symptoms such as erythema and desquamation. Furthermore, extracellular vesicles prepared using TRT-2A can effectively improve skin elasticity and reduce wrinkles. Therefore, the Bifidobacterium animalis subspecies TRT-2A of this invention has multiple functions and is worthy of further promotion and application.

The application discloses a super-sensitive detection composition of aquatic product pathogenic bacteria and an application and a detection method thereof, and belongs to the technical field of biotechnology.The composition comprises an amplification primer with a sequence shown as SEQ ID No.1-2, a hairpin probe H1 with a fluorescent group and a quenching group modified on a nucleotide sequence shown as SEQ ID No.3, and a hairpin probe H2 with a sequence shown as SEQ ID No.4.Compared with conventional detection technologies such as a bacterial culture method, an instrument analysis method, a molecular biology method and an immunology method, the application provides a set of amplification primers and hairpin probes based on HCR, has higher specificity when detecting escherichia coli of aquatic products, and can avoid the influence of staphylococcus aureus, streptococcus pyogenes, pseudomonas aeruginosa and salmonella; meanwhile, the application has better sensitivity, and the detection limit can reach 0.4 CFU / mL; in addition, compared with other hairpin probes, the application can avoid false positives and improve reaction efficiency.

The application discloses a private part care spray capable of balancing private part microecology, removing peculiar smell, killing bacteria and resisting viruses, and belongs to the technical field of private part care and disinfection materials. The private part care spray is prepared by compounding 3.8-6.5 parts of a modified edible bactericide, 3.2-5.5 parts of food-grade lactic acid, 2.2-3.0 parts of modified food-grade gentian root extract and the rest food-grade deionized water. The activity and stability of raw materials are improved through the processes of β-cyclodextrin inclusion modification of the bactericide and compounding of the modified product with the modified food-grade gentian root extract. The product has a killing rate of 99.9% on Neisseria gonorrhoeae, Gardnerella vaginalis, Bacteroides, Streptococcus pyogenes, Candida albicans, Staphylococcus epidermidis, Escherichia coli and Pseudomonas aeruginosa, an inactivation rate of 99.99% on herpes simplex virus SHV-2 and HPV16 virus, an ammonia removal rate of 95%, a peculiar smell inhibition duration of 48 h and a mucous membrane irritation level of 0, and the preparation process is simple and suitable for industrial production.

This invention belongs to the field of probiotic screening and application technology, specifically relating to a strain of *Bifidobacterium longum* subsp. *longum* and probiotic pellets containing this strain, as well as their applications. The *Bifidobacterium longum* subsp. *longum* has the accession number CCTCC NO: M2026130 and can significantly inhibit the growth of *Streptococcus pyogenes*, and can efficiently flocculate with *Streptococcus pyogenes*. The probiotic pellets provided by this invention have strong acid resistance, enteric solubility, and storage stability, and can be widely used for the prevention or treatment of *Streptococcus pyogenes*-induced colonic polyps and colon cancer, showing broad prospects.