81 results about "Proteus" patented technology

The invention discloses application of a Harmine derivative to preparation of antibacterial medicines. The bacteria is selected from Acinetobacter, Bacillus, Campylobacter, Chlamydia, Chlamydia trachomatis, Clostridium, Citrobacter, Escherichia, enterohemorrhagic escherichia coli, enteric bacteria, Enterococcus, Francisella, Haemophilus, helicobacter, Klebsiella Bacillus, Lester monocytogenes, Moraxella, Mycobacterium, Neisseria, proteus, Pseudomonas, Salmonella, shewanella oneidensis, Shigella, Stenotrophomonas, Staphylococcus, Streptococcus and Yersinia.

The invention discloses a pseudomonas proteus znuA gene stable silencing strain and application. The pseudomonas proteus znuA gene stable silencing strain is constructed through a gene silencing technology, then the pathogenicity of the znuA gene stable silencing strain to epinephelus coioides is determined through an artificial infection experiment, transcriptome data of spleens of the epinephelus coioides infected by a wild strain and the znuA gene stable silencing strain is analyzed by utilizing a dual RNA-seq technology, meanwhile, transcriptome data of hosts and pathogenic bacteria is researched, the function of a znuA gene in interaction of pseudomonas proteus and the epinephelus coioides is discussed from the transcriptome level, and then the influence of the znuA gene on the toxicity of the pseudomonas proteus is disclosed. The constructed strain has the advantages that the pathogenicity to the epinephelus coioides is remarkably reduced, and the transcriptome data of the pseudomonas proteus and the epinephelus coioides in the infected spleens can be remarkably changed, so that the strain can be used for researching the pathogenic mechanism of the pseudomonas proteus.

The invention discloses a method for preparing a natural red jujube skin pigment and application of the natural red jujube skin pigment. The method comprises the following steps of: removing jujube flesh from red jujubes to obtain red jujube skin; drying the red jujube skin, crushing, leaching in a weak base solution, and filtering to obtain a red jujube skin pigment stock solution; and concentrating, drying and crushing the red jujube skin pigment stock solution to obtain powdered natural red jujube skin pigment. According to the method, a process is simple and low in cost and is suitable for large-scale production; and the powdered red jujube skin pigment ensures the stability and wide application of the pigment. The prepared natural red jujube skin pigment has the antibacterial activity on gram-positive bacteria of staphylococcus aureus, listeria monocytogenes, lactobacillus, alicyclobacillus and the like and on gram negative bacteria of escherichia coli, proteus, shigella dysenteriae, pneumobacillus, acinetobacter and the like.

The invention discloses a method for planting rhizoma polygonati. The method comprises following steps: land selection, land preparation, rhizome selection and treatment, rhizome planting, field management and harvesting. In the treatment of rhizomes, potassium hydroxide solution is first used to sterilize the rhizomes, and then self-made treatment liquid is used to soak the rhizomes and further sterilize the rhizomes, so as to improve the antibacterial ability of rhizomes. The cortex moutan in the self-made treatment liquid contains gallic acid, which has a strong inhibitory effect on variousfungi such as Bacillus subtilis and Proteus. The composition contains grapefruit peel, elsholtzia splendens leaf and pearl plum, and the volatile oil of the three also has a strong smoke-killing effect on pests and colonies. The rhizome of Polygonatum sibiricum is sterilized with potassium hydroxide solution and then soaked in self-made treatment liquid to kill harmful bacteria and microorganismscarried by rhizome of Polygonatum sibiricum, which greatly enhanced its antibacterial ability, avoided the rot and mildew of rhizome, and increased the rate of seedling emergence.

The inventiona relates to bromo-2, 4í»-dihydroxyl diphenyl ether compound and its synthesizing method, using 2-methoxy phenol and 4-methoxy chlorobenzene as raw materials, and it is an antimicrobial obtained by three-step reaction, and has better antimicrobial activity to Escherichia coli, catarrh diplococcus, Staphylococcus aureus, Staphylococcus Albus, bacillus proteus, etc. and avoids producing highly toxic dioxin compound in the producing and using course, avoiding environmental pollution and damaging human health; and also overcomes the shortages that natural bromic2, 4í»-dihydroxyl diphenyl ether antimicrobial can form highly toxic dioxin compound in use on certain conditions, and the natural bromic2, 4í»-dihydroxyl diphenyl ether antimicrobial has limited source, complex extracting course and high cost..

The invention discloses a compound bacterial agent for promoting the growth of the flathorned soldier fly larvae and its application. The composite bacterial agent for promoting the growth of the soldier fly larvae provided by the invention comprises: Cochlear bacterium ( Kocuria marina ) FE01, Lysinibacillus boronitolerans FE04, Proteus mirabilis ( Proteus mirabilis ) FE08 and Bacillus subtilis BSF‑CL is used to promote the growth of soldier flies in the process of converting soldier flies into chicken manure, which is safe and environmentally friendly. By adding the agent to the chicken manure containing soldier flies, the weight gain of soldier flies can be increased by 28.57% compared with the conversion system without adding bacteria. Benefits have great economic value.

The invention discloses a traditional Chinese medicine preparation for damp-heat detoxifcation and consists of honeysuckle, dandelion, field pennycress, radix scutellariae, raw coix seed, alisma orientale, red paeonia, lightyellow sophora root and tail of angelica sinensis. The traditional Chinese medicine preparation is prepared by scientific processing technique; by adopting traditional Chinese medicine theory, the traditional Chinese medicine preparation can treat purulent inflammation caused by the retention of damp-heat internally, exogenous affection of pathogenic damp-heat and toxicity and stagnation on the skin, which is proved by clinical application. The honeysuckle, dandelion, field pennycress has the function of clearing away heat and detoxifcation, radix scutellariae can clear away lung heat, red paeonia and tail of angelica sinensis can cool the blood and activate the blood circulation, and raw coix seed and lightyellow sophora root can clear away heat, strengthen the spleen and remove dampness. The invention is a pure traditional Chinese medicine preparation, and has remarkable inhibitory effect on staphylococcus, colon bacillus, streptococcus, pneumococci, meningococcus, proteus and pseudomonas aeruginosa. Furthermore, the invention has convenient therapy and significant clinical effect and diseases are not likely to recur after curing.

The invention discloses a heparin lyase mutant and a recombinant expression method thereof, belonging to the technical field of bioengineering. The heparin lyase III provided by the invention has higher catalytic efficiency and thermal stability, and the catalytic efficiency of the mutant S264F / Y490K / D321N is 1.68 times higher than that of the original strain, which is more conducive to the preparation of low molecular weight heparin. The invention also performs heterologous recombination expression on the heparin lyase III from the Bacteroides proteus, and the intracellular enzyme activity can reach more than 4000U / L.