246 results about "Antimicrobial action" patented technology

The invention belongs to the technical field of genetic engineering, and particularly relates to an antibacterial peptide with antibacterial and antiviral effects and application and a product thereof. The amino acid sequence of the antibacterial peptide provided by the invention has the following general formula: X1GX2FX3FX4KKFX5LFX6X7SKVLK, x1 is M or has no amino acid; x2 is one of R, G and H; x3 is one of KS, KR, HR and HH; x4 is R or L; x5 is one of KK, HH and HK; x6 is RR or KK; and X7 is I or L. The antibacterial peptide disclosed by the invention has a relatively good antibacterial effect, and shows antiviral activity on HPV16 (Human Papilloma Virus 16) and HPV18 (Human Papilloma Virus 18). Good application prospects are shown in the preparation of antibacterial or antiviral products.

The invention relates to the technical field of marine antifouling materials, in particular to a modified polyurethane marine antifouling coating based on a metal pyridine structure and a preparation method. According to the modified polyurethane marine antifouling paint based on the metal pyridine structure, polyhydric alcohols and diisocyanate monomers with different molecular weights are subjected to condensation polymerization to obtain a polyurethane prepolymer; then reacting a diaminopyridine monomer or a dihydroxypyridine monomer with a metal ion compound to obtain a chain extender with a metal pyridine structure; finally, the marine antifouling paint is prepared through the reaction between the terminal amino or hydroxyl of the metal pyridine structure chain extender and the terminal isocyanate group of the polyurethane prepolymer, the metal pyridine structure is introduced into polyurethane, the mechanical performance of the marine antifouling paint is enhanced, the marine antifouling paint is endowed with the antibacterial effect through metal ion release, and the service life of the marine antifouling paint is prolonged. Adhesion and growth of marine fouling organisms can be effectively inhibited, and an efficient and durable solution is provided for development of a polyurethane marine antifouling coating.

The present invention belongs to the field of biomedicine, and specifically relates to an antimicrobial peptide derived from lactoferrin and its application. The antimicrobial peptide derived from lactoferrin, whose amino acid sequence is shown in any one of SEQ ID NOs: 1 to 98, has a broad-spectrum antimicrobial effect, especially significant antibacterial effect against Pseudomonas putida, Rhodococcus erythropolis, Bacillus subtilis, Malassezia furfur, Cryptococcus neoformans, and Candida albicans, and has great application value.

The invention discloses an antibacterial breathable dressing patch and a preparation method thereof, and belongs to the field of medical dressings, the antibacterial breathable dressing patch comprises a Janus type dressing patch layer which is a composite film containing a hydrocolloid matrix, pH response antibacterial microspheres and bioactive glass nanoparticles; the super-hydrophobic electrostatic spinning outer layer is a super-hydrophobic electrostatic spinning fiber membrane, and the super-hydrophobic electrostatic spinning outer layer and the Janus type dressing skin-attaching layer are compounded to form an asymmetric Janus structure, intellectualization and precision of the antibacterial effect are achieved, and the risks of cytotoxicity and bacterial drug resistance possibly caused by long-term exposure to an antibacterial agent are reduced to the maximum extent; a multi-mechanism and synergistic antibacterial defense system is constructed, more comprehensive and firm protection is provided for wounds, the air permeability and moisture permeability are excellent, a dry and moist ideal healing environment is created for the wounds, the biocompatibility is good, the use safety is high, the wound healing agent is mild to human tissues, the irritation is low, the allergic reaction risk is small, the safety is high, and the wound healing effect is good. The long-term use is facilitated.

Despite the existence and deployment of a range of antimicrobial / disinfectant / sterilization technologies and products, transmission of infectious diseases remains a significant problem worldwide, continuing to cause hundreds of millions of infections and millions of deaths every year of both human beings and animals. State-of-the-art technologies suffer from several disadvantages including being discrete in space and time, being overly dependent on human skill and discipline, and in some cases having harmful side-effects to human health. This invention proposes a series of industrial grade antimicrobial product designs, and materials and methods to make them highly effective products that offer continuous antimicrobial action, with minimum dependence on human discipline and skill once deployed, and with no harmful side-effects.

The invention discloses an antibacterial nylon 6 material as well as a preparation method and application thereof, relates to the technical field of nylon materials, and solves the problem that the antibacterial property and the mechanical property of nylon are difficult to consider at the same time. The material has a structure shown as a formula (I), R1 and R2 are independently selected from one of C1-24 linear chain / branched chain aliphatic groups, substituted / unsubstituted C3-12 alicyclic hydrocarbon groups / C6-18 aryl groups / C7-30 aralkyl groups, or R1 and R2 on the same N and connected N form 5-7-membered saturated / unsaturated heterocyclic rings; and each E-group is independently selected from the structural general formula (II). Each R3 is independently selected from one of C1-24 linear chain / branched chain aliphatic groups, substituted / unsubstituted C3-12 alicyclic hydrocarbon groups, C6-18 aryl groups and C7-30 aralkyl groups; x is an integer selected from 1 to 18; m is equal to 0.01-0.50, and m + n is equal to 1. The antibacterial nylon 6 material has a broad-spectrum and efficient antibacterial effect, is lasting in antibacterial effect and excellent in mechanical property, and can be used for preparing textiles, daily necessities, building materials, packaging materials or panels. # imgabs0 #

The invention discloses toothpaste which is pasty and comprises an abrasive, a humectant, a foaming agent, water, a bacteriostatic agent povidone iodine, 0.5 wt%-5 wt% of magnesium carbonate particles and 5 wt%-15 wt% of chitosan.The toothpaste has the advantages that cross-linking points are formed through electrostatic attraction between a positively charged chitosan acid solution and negatively charged povidone iodine and silicon dioxide particles; the preparation method comprises the following steps: preparing chitosan by virtue of a sol-gel method so as to realize gelation of the chitosan, uniformly dispersing silicon dioxide particles, povidone iodine and magnesium carbonate nanoparticles in the chitosan gel to obtain pasty toothpaste with good performance, the pasty toothpaste has relatively good stability, and the gel structure can also be used as a carrier to load and slowly release povidone iodine, so that the antibacterial action time of the povidone iodine is prolonged, and long-acting antibacterial protection is provided. The toothpaste disclosed by the invention has a good cleaning effect and antibacterial performance, is suitable for more user groups, especially crowds with sensitive oral cavities, and has important market requirements and application prospects.

The invention relates to the technical field of antibacterial peptides, in particular to application of an antibacterial peptide RV-18-ack in preparation of an antifungal product. The antibacterial peptide RV-18-acy disclosed by the invention comprises a polypeptide RV-18 of which the amino acid sequence is shown as SEQ ID NO. 1. The antibacterial peptide RV-18-ack is a polypeptide capable of forming an amphiphilic alpha helical structure, can form nanoparticles in a self-assembly manner, has broad-spectrum antifungal activity, can damage fungal cell membranes in a targeted manner to play a bactericidal role, shows a relatively good antibacterial role on candida albicans, has the minimum inhibitory concentration of 2.344-75 mu M, and is free of cytotoxicity and hemolysis; besides, the antibacterial peptide RV-18-ack contains 18 amino acids, and all the amino acids are L-type amino acids, so that the production cost is greatly reduced, and the antibacterial peptide RV-18-ack is expected to become a novel broad-spectrum antifungal candidate drug and has a good application prospect in the aspect of resisting super fungi.

The present invention relates to the technical field of oral medicine and oral medical products, and in particular to a targeted nano-enzyme antibacterial agent having an oral microbiota level adaptive regulation function and a preparation method therefor. Specifically, a nitrogen-doped zeolite imidazolate framework material is used as a carrier; a bimetallic monatomic nano-enzyme is prepared by means of a pyrolysis method; and an antibacterial peptide is used as a surface anchoring body and is modified on the surface of the nano-enzyme, so that a multifunctional nano-enzyme having a high targeting colonization ability, a high-efficiency antibacterial biofilm and an antibacterial effect is obtained. Also provided are a pharmaceutical composition, an antibacterial agent, and an oral care product containing the nano-enzyme.

The invention belongs to the technical field of pet products, and particularly discloses a novel anthelmintic based on fipronil drops, which can effectively reduce the bacterial or fungal infection caused by parasites on the body surface or skin of pets by combining the antibacterial effects of fipronil, citronella extract and tripterygium wilfordii. The fipronil can quickly kill parasites, the citronella extract can further reduce breeding and contact of the parasites through a repelling effect, so that the overall effect of the medicine is accelerated, the citronella extract further reduces the secondary infection risk caused by the parasites by inhibiting growth of bacteria, and the tripterine further reduces the secondary infection risk caused by the parasites by inhibiting pathogenic microorganisms of skin. Through the synergistic effect of multiple components, the development of drug resistance of parasites to a single component can be reduced.

A preparation method for a food nanofiber film having sustained-release antibacterial activity, and a use thereof, belonging to the technical field of food packaging films. A metal-organic framework material MIL-101(Fe) is used to encapsulate natural plant essential oils, while polylactic acid and polycaprolactone are used as film-forming substrates, to prepare a food nanofiber film capable of exerting a long-term and efficient antibacterial effect; by means of encapsulating highly volatile natural plant essential oils with MIL-101(Fe), the residence time of antibacterial substances in the top space of the packaging film can be extended, increasing the utilization of the essential oils and achieving long-lasting antibacterial effects. Moreover, MIL-101(Fe) has a specific surface area of 2865 m2 / g, which can greatly improve the encapsulation rate and sustained-release effect of the plant essential oils. At the same time, the film, prepared by electrospinning, has a high specific surface area, which is conducive to increasing the encapsulation rate of the plant essential oils. This preparation method is safe, environmentally friendly, simple to operate, and easy to promote and apply.

The present disclosure relates to a sock or shoe cover having grip features comprising at least one antimicrobial agent. The plurality of grip features are arranged on a plantar surface contact face. Optionally, a plurality of antimicrobial dorsal grip features are arranged about a dorsal face of the sock or shoe cover. In certain embodiments, a sock body of the sock or shoe cover also has antimicrobial qualities. In a second aspect, a method of reducing or eliminating the transportation of microbes from footwear is provided.

Disclosed embodiments relate to wound care materials and methods that comprise a self-gelling composition, configured to form a gel upon contacting fluid. The self-gelling composition is a substantially homogeneous mixture, and comprises fluid-absorbent particles loaded with iodine-based antimicrobial agent, a dehydrated hydrogel powder, and a polymer base, configured to allow dispensing the self-gelling composition from a syringe or tube and to prevent the self-gelling composition from gelling prior to contacting fluid. The gel performs one or more of the following tasks during a wear time, when applied at the wound: absorbing fluid or exudate, releasing iodine-based antimicrobial agent, achieving antimicrobial activities at the wound, remaining structurally integral and cohesive, protecting the wound from exposure to microorganisms, and facilitating healing. After a wear time of at least three days, the gel can be removed in two pieces or less and leave less than 5% residue by weight.

The invention provides an ionic liquid antibacterial disinfectant, belongs to the technical field of medical preparations, and aims to solve the technical problem that chemical disinfectants are harmful to human bodies. The ionic liquid antibacterial disinfectant comprises an ionic liquid and deionized water, the proportion of the ionic liquid is 0.01%-100% by weight, and the proportion of the deionized water is 0%-99.99% by weight. The cation of the ionic liquid is imidazole, amine, piperidine or pyridine, and the anion of the ionic liquid is theophylline salt, mandelate, chlorine salt or dicyanide salt. The ionic liquid antibacterial disinfectant provided by the invention has a good sterilization effect, belongs to a novel antibacterial disinfectant which is non-volatile, non-irritant, healthy and environment-friendly, and has the characteristics of wide application scene, excellent sterilization effect, long antibacterial action time and environment friendliness.

The invention relates to the technical field of anti-cancer chemical drugs, in particular to a thiadiazole tetranuclear copper complex with anti-tumor and antibacterial activity and a preparation method and application of the thiadiazole tetranuclear copper complex. The chemical formula of the complex is [Cu4 (C3H3S2N2) 2 (C3H4S2N2) 4], the complex is synthesized from ligand thiadiazole and CuX, X is I or Br, and copper in the obtained complex is + 1 valence. The complex shows a good cytotoxic effect on breast cancer cells MCF-7, is likely to play a toxic effect by inducing apoptosis, ferroptosis, copper death and other ways, has a good antibacterial effect, has potential medicinal value, and is expected to be developed into a new generation of anti-tumor drugs with antibacterial properties.

The present invention relates to the technical field of dyes, and discloses a plant dye for silk fabrics and a preparation method thereof. The present invention is provided by adding turmeric dye, phellodendron dye, antibacterial liquid, quaternized chitosan and water into a stirrer, stirring at room temperature, and obtaining the plant dye for silk fabrics after the end. The antibacterial liquid and quaternized chitosan contain a large amount of quaternary ammonium salt groups, which play a good antibacterial role. The cardanol in the antibacterial liquid itself has a certain antibacterial effect, and synergistically antibacterial with the quaternary ammonium salt. The sulfur element contained in the antibacterial liquid can promote the dehydration of the polymer substrate into carbon during the heating process. This carbon layer can effectively isolate the contact between oxygen in the air and the polymer substrate, thereby achieving a flame retardant effect; the boron element can form a glassy coating covering the polymer when heated, and the coating can effectively isolate oxygen and heat, thereby protecting the internal polymer from further combustion, thereby achieving a flame retardant effect.

The present application relates to an antifungal microneedle patch and its preparation method and application, the antifungal microneedle patch includes backing layer and the needle head arranged on the surface of the backing layer;The needle head constitutes n×n array on the surface of the backing layer;The surface of the needle head includes fatty acid coating containing antibacterial drug;The inside of the needle head includes photosensitizer;The n is selected from integer.The antibacterial drug is lipophilic triazole antifungal drug.The fatty acid is selected from saturated fatty acid containing 6-12 carbon atoms.The present application innovatively combines antifungal drug itraconazole and photo-thermal agent / photosensitizer indocyanine green, loads in microneedle, can carry out painless minimally invasive local administration, through the antibacterial action, photo-thermal effect and photodynamic effect of antifungal drug released under the excitation of near-infrared light, realize the effective killing to fungi, and will not cause irreversible damage to normal tissue.

The application discloses a preparation method of honey-mediated silver nanoparticle / attapulgite composite antibacterial material, which comprises the following steps: dissolving natural honey in water to form a honey aqueous solution under stirring, dispersing attapulgite powder into the honey aqueous solution to obtain a uniform mixed solution, adding silver nitrate aqueous solution dropwise into the mixed solution, adjusting the pH of the mixed solution to 8-9, and continuously stirring the mixed solution at room temperature for 3-6 hours; and centrifuging, washing and drying the obtained product to obtain the silver nanoparticle / attapulgite composite antibacterial material. The active components in the honey are used as a reducing agent and a stabilizer, the silver nanoparticle / attapulgite composite antibacterial material is synthesized by one-step method, the preparation process is green, simple and efficient; the natural attapulgite is used as a carrier, on the one hand, the generation process of the silver nanoparticles is regulated, and the technical problem of effectively reducing the agglomeration of the silver nanoparticles is solved; and on the other hand, the biological activity is synergistically enhanced, so that the silver nanoparticles can play a more efficient antibacterial role and the application safety is improved.

The application discloses a silver / schiff base antibacterial material, a preparation method and application, and relates to the field of antibacterial materials.The silver / schiff base antibacterial material, the preparation method and the application are characterized in that, based on the large electron cloud density of the carbon-nitrogen double bond of the schiff base, silver ions in a silver nitrate solution are uniformly adsorbed on a schiff base base through the electrostatic adsorption principle; under the reduction of a reducing agent, the silver ions are reduced to nanosilver ions, and a silver / schiff base antibacterial material is obtained, in which nanosilver ions in the form of nanospheres are uniformly dispersed on the schiff base in the form of a thin sheet layer, thereby greatly improving the dispersibility of the nanosilver ions.The preparation method is simple, low in cost, and capable of batch production, and has no cytotoxicity, and has high antibacterial effects on streptococcus, pseudomonas aeruginosa and staphylococcus aureus, and has a good application prospect.

The invention discloses a rolling method for an antibacterial titanium alloy plate, relating to the technical field of titanium alloy materials. An antibacterial agent, modified chitosan and guar gum are mixed, glycerol is used as a plasticizer, and ammonium tripolyphosphate is used as a cross-linking agent to prepare an antibacterial coating, which is then coated on the surface of the titanium alloy. The alkylated chitosan has a long hydrophobic chain and is tightly cross-linked with the guar gum under the cross-linking action of sodium tripolyphosphate, thereby synergistically improving the hydrophobic effect of the coating and blocking the adhesion of moisture and bacteria. Silver nanoparticles are evenly dispersed on the surface of montmorillonite. Through the effective combination of the two antibacterial effects, the antibacterial effect of the coating is fully exerted, while also protecting the titanium alloy plate and improving its corrosion resistance.

This invention discloses a bioactive glass and its preparation method, belonging to the field of bioactive glass technology. It aims to solve the problems of insufficient synergistic effect between antibacterial efficacy and bone-promoting activity in existing materials, as well as the inability to monitor in vivo degradation processes in real time. The bioactive glass comprises 44-48 parts silica; 22-27 parts calcium oxide; 22-27 parts sodium oxide; 5-7 parts phosphorus pentoxide; 2-4 parts europium zinc complex; 10-20 parts chitosan; 1-5 parts lidocaine; and 2-5 parts dilute acetic acid solution. The addition of the europium zinc complex promotes bone formation and enhances antibacterial activity, achieving a highly efficient synergy between anti-infection and tissue regeneration. Simultaneously, it provides optical tracking capabilities, allowing for non-destructive real-time monitoring of the material's degradation behavior and tissue integration in vivo via fluorescence imaging. This invention offers superior material performance and a simple preparation process, providing an innovative solution for the repair of infected bone defects.

The invention relates to a veterinary hoof disease prevention and treatment composition as well as a preparation method and application thereof, and aims to solve the technical problems that existing commercial hoof bath lotion is limited in sterilization effect and relatively strong in local irritation, and a safe and efficient treatment medicament for treating cow hoof warts is lacked and the like. The invention provides a veterinary composition which comprises the following active ingredients: a glycyrrhizic acid compound, didecyl methyl ammonium bromide and polyhexamethylene guanidine salt, and the three components are combined, so that the composition has an antibacterial effect and an effect of promoting skin tissue repair at the same time. A series of tests prove that the traditional Chinese medicine composition can effectively inhibit animal pathogenic bacteria, prevent and / or treat animal limb and foot diseases and promote healing and repairing of ulcer injury. The medicament disclosed by the invention is suitable for preventing and treating limb and hoof diseases in a large-scale pasture, has the characteristics of high sterilization efficiency, good safety and effective treatment, and can improve the animal hoof health management level.

The invention relates to a dental and / or oral care product comprising between 0.0039% and 0.0078% by weight of nisin establishing and / or maintaining a pH of at least 4.5 in situ. Although said rather low nisin concentration does not provide an anti-bacterial effect, it is surprisingly and advantageously capable of maintaining stable pH values of at least 4.5, thereby preventing destruction of a subject's teeth enamel based on enamel demineralization effects at pH below 4.5, and said low nisin concentration advantageously further avoids dysbacteriosis, i.e. the oral microflora remains balanced, thus not leading to an increase of e.g. periodontitis associated bacteria.

The invention provides a polyolefin master batch with antibacterial and antioxidant functions and application, and belongs to the technical field of plastics. The polyolefin master batch is prepared from the following components in percentage by mass: 92 to 99 percent of polyolefin, 1 to 5 percent of titanium dioxide embedded tea polyphenol nano microspheres and 0 to 3 percent of modified nano zinc oxide. Through the structural design of the titanium dioxide embedded tea polyphenol nano-microspheres, the structure of the internal tea polyphenol is protected, in the use process, the tea polyphenol can be slowly released to achieve a continuous anti-oxidation effect, and the added nano-zinc oxide can form a heterojunction structure with the titanium dioxide embedded tea polyphenol nano-microspheres, so that the oxidation resistance of the tea polyphenol nano-microspheres is improved. The anti-ultraviolet capacity is enhanced while the antibacterial effect is achieved, and the multifunctional polyolefin master batch with the antioxidant, antibacterial and anti-ultraviolet functions is formed after the polyolefin master batch is blended with polyolefin.

Despite the existence and deployment of a range of antimicrobial / disinfectant / sterilization technologies and products, transmission of infectious diseases remains a significant problem worldwide, continuing to cause hundreds of millions of infections and millions of deaths every year of both human beings and animals. State-of-the-art technologies suffer from several disadvantages including being discrete in space and time, being overly dependent on human skill and discipline, and in some cases having harmful side-effects to human health. This invention proposes a series of industrial grade antimicrobial product designs, and materials and methods to make them highly effective products that offer continuous antimicrobial action, with minimum dependence on human discipline and skill once deployed, and with no harmful side-effects. Methods may include either or both first and second materials be formed by vapor or solution-based coating schemes and many may be antimicrobial in nature. Nanopores and / or nanotubes produce an ultra-high anti-microbially active surface area.

The utility model relates to the technical field of in-vitro positioning patches, and discloses a bacteriostatic medical image in-vitro positioning patch which comprises a lower layer, two bacteriostatic mechanisms, two sensors, two embedded cylinders and three large sticky pieces, an upper layer is fixedly arranged on the upper end face of the lower layer, a bottom layer and a breathable layer are arranged in the lower layer, and the breathable layer is fixedly arranged on the upper end face of the lower layer. A surrounding adhesive sheet is fixedly arranged at the completion position of the lower end face of the lower layer, the two bacteriostatic mechanisms comprise two outer frames, two bacteriostatic materials and four clamping blocks, and a plurality of taper holes are formed in the upper end faces of the two bacteriostatic mechanisms. According to the utility model, the bacteriostatic material is arranged in the bacteriostatic mechanism, the bacteriostatic material is made of silver ions, and nano-silver has excellent antibacterial performance and can continuously release the silver ions when being in contact with water or moisture, so that the antibacterial effect of the nano-silver is exerted; and the volatilization layers above and below the antibacterial material can prevent the antibacterial material from quickly volatilizing, so that the antibacterial effect of the positioning patch is better.

The invention discloses a novel liquid-holding particle type iodine-loaded antibacterial agent-ionic liquid gel iodine-loaded microsphere preparation method, which comprises the following steps: by taking polymethyl methacrylate as a network, a hydrophobic ionic liquid as a dispersion medium, methyl methacrylate as a monomer and azodiisobutyronitrile as an initiator, embedding molecular iodine in situ in the network, and preparing the novel liquid-holding particle type iodine-loaded antibacterial agent-ionic liquid gel iodine-loaded microsphere. The ionic liquid gel iodine-loaded microspheres are prepared. The ionic liquid cation imidazolyl group in the microbial agent can vertically act on a phospholipid bilayer on a bacterial cell membrane, and the hydrophobic end can destroy the complete structure of the cell membrane due to electrostatic interaction, so that substances outside the cell enter the cell or substances inside the cell leak out, and the cell is inactivated. Meanwhile, surface iodine in the ionic liquid gel iodine-loaded microspheres has an antibacterial effect, and the ionic liquid gel iodine-loaded microspheres and the surface iodine jointly inhibit growth of bacteria. The novel liquid-holding particle type iodine-loaded antibacterial agent-ionic liquid gel iodine-loaded microsphere is a novel solid-liquid composite polymer antibacterial material, and has the characteristics of simple preparation method, wide application range, excellent antibacterial performance and the like.

The application belongs to the technical field of genetic engineering, and particularly relates to an antibacterial peptide with antibacterial and antiviral effects, application and product thereof. The amino acid sequence of the antibacterial peptide has the following general formula: X1GX2FX3FX4KKFX5LFX6X7SKVLK; X1 is M or no amino acid; X2 is one of R, G and H; X3 is one of KS, KR, HR and HH; X4 is R or L; X5 is one of KK, HH and HK; X6 is RR or KK; and X7 is I or L. The antibacterial peptide has good antibacterial effect, and shows antiviral activity to HPV16 and HPV18. The antibacterial peptide shows good application prospect in preparation of antibacterial or antiviral products.

The invention relates to the technical field of antibacterial peptides, in particular to an antibacterial peptide RV-18-ack and application thereof in preparation of antibacterial products. The antibacterial peptide RV-18-ack provided by the invention comprises a main chain and fatty acid modified at a C end or an N end of the main chain, the amino acid sequence of the main chain is as shown in SEQ ID NO. 1. The antibacterial peptide RV-18-ack provided by the invention is a polypeptide capable of forming an amphiphilic alpha helical structure, has broad-spectrum antibacterial activity, shows a better antibacterial effect on acinetobacter baumannii, pseudomonas aeruginosa, escherichia coli and staphylococcus aureus, has the minimum inhibitory concentration of 1.17-4.69 mu M, and is free of cytotoxicity and hemolysis; all amino acids are L-type amino acids, so that the production cost is greatly reduced, and the compound is expected to become a novel broad-spectrum antibacterial candidate drug and has a good application prospect in the aspect of resisting super bacteria.

The present invention relates to a compound selected from novel triazine derivative compound, a pharmaceutically or sitologically acceptable salt thereof, a solvate thereof, or a stereoisomer thereof, and a use thereof. With a potent antibacterial effect, the amphiphilic triazine compound according to the present invention can be safely and effectively used as an excellent antibacterial composition and a therapeutic composition for microbial infectious diseases.