49 results about "Fipronil" patented technology

The invention relates to the technical field of immunochromatography analysis, and discloses a signal enhancer of a colloidal gold immunochromatography rapid detection card and a preparation method thereof, the signal enhancer comprises a silver ion solution, a thiourea-ascorbic acid synergistic reducing agent, a pH buffer system and a surfactant stabilizing system, the signal amplification is realized by catalyzing and depositing silver nanoparticles on the surface of colloidal gold, the operation is simple and convenient, one-time addition is realized, and the reaction is completed within 5-10 minutes; the sensitivity is improved by 5-10 times, and the specificity is higher than 98%; the stability is excellent, and the storage time is 12 months at 4 DEG C; various colloidal gold rapid detection cards are universally compatible; compared with the prior art, the colloidal gold immunochromatography rapid detection card has the advantages that the cost is controllable, the single detection is increased by 0.3-0.5 yuan, and the colloidal gold immunochromatography rapid detection card is particularly suitable for ultra-sensitive detection of small molecular substances in the field of food safety, for example, the detection limit of malachite green reaches 0.1 microgram per liter, the detection limit of fipronil reaches 0.5 microgram per liter, and the application range of the colloidal gold immunochromatography rapid detection card is obviously expanded.

The invention belongs to the technical field of synthesis of organic compounds, and particularly relates to a process for preparing fipronil and an intermediate thereof. Toxic 1, 2-dichloroethane is comprehensively replaced by bio-based gamma-valerolactone, low-toxicity cyclopentyl methyl ether is matched, and N, N-dimethylformamide necessary for the process is recycled, so that consumption is greatly reduced; the continuous processes of amination, diazotization and the like are realized through a tubular reactor, a micro-reactor and a static mixer, and separation technologies such as pervaporation membrane and vacuum distillation are combined, so that the reaction time is shortened, the solvent recovery rate is increased, and the production is promoted to be continuously transformed to green. The supported FeCl3 / SiO2-NH2 catalyst disclosed by the invention can be repeatedly used, and byproducts and tail gas can be recycled and reused. In addition, diazonium salt residues are controlled to be smaller than or equal to 0.5% through near infrared spectroscopy, citric acid is subjected to stable oxidation reaction, a purification process is combined, it is ensured that the finished product is high in purity, excellent in yield and small in batch fluctuation, and efficiency and safety are both considered.

The present disclosures presents a insecticidal composition comprising a combination of active ingredients, Spiromesifen, abamectin, and Fipronil and methods of preparing and using such compositions. The present disclosure aims to provide enhanced control of a variety of insect pests affecting crops, with a synergistic effect that improves efficacy compared to individual components.

The invention discloses a mosquito prevention and control composition based on jonquil extract and application of the mosquito prevention and control composition. The invention provides an application of an ethanol extract of jonquil leaves in killing mosquitoes or preparing products for killing mosquitoes. The invention firstly proves that the kalanchoe blossfeldiana ethanol extract has a killing effect on three mosquito species, and the killing effect is obviously superior to that of kalanchoe laciniata which is the same family plant. The invention further provides a mosquito prevention and control composition containing the ethanol extract of the jonquil leaves and a mosquito prevention and control compound composition containing the ethanol extract of the jonquil leaves and dinotefuran. The insecticide poison bait prepared by compounding the jonquil extract and the chemical insecticide provides a new thought for constructing an efficient, low-consumption and environment-friendly mosquito comprehensive treatment system, and is suitable for comprehensive prevention and control of mosquito-borne diseases.

The present invention relates to a method for efficiently synthesizing fipronil, belonging to the field of pesticide synthesis. The present invention utilizes an anhydrous solid base to catalyze hydrogen peroxide in a milling system to oxidize sulfide, thereby improving stirring and mixing efficiency, shortening reaction time, and thereby reducing the content of peroxide impurities (sulfones). High-content fipronil can be obtained without requiring multiple crystallizations. The method has a short reaction time, low raw material costs, is environmentally friendly, and has high product purity and yield, making it easy to industrialize.

The invention belongs to the technical field of termite prevention and control, and discloses a termite trapping and killing agent and a preparation method thereof.The termite trapping and killing agent is prepared from, by weight, 25-30 parts of pine sawdust powder, 10-20 parts of dustpan, 8-12 parts of sugarcane powder, 4-6 parts of pine pollen, 6-10 parts of compound insecticide, 1-3 parts of pheromone sustained-release microcapsules, 15-25 parts of hydrogel cellulose composite carrier and 1-3 parts of hydrocarbon mixing agent; according to the termite trapping and killing agent, fipronil and hexaflumuron are compounded, the termite killing effect is improved by compounding two agents with completely different action mechanisms, and the discovery rate, the feeding rate and the agent transmission efficiency of termites can be remarkably improved by adding the pheromone sustained-release microcapsules, the hydrogel cellulose composite carrier and the hydrocarbon mixing agent; and finally, eradication prevention and control on the ant nests are achieved, the environmental adaptability is high, and the lasting period is longer.

A pesticidal composition comprising (A) chlorantraniliprole, (B) fipronil, (C) metalaxyl or metalaxyl-M, (D) fludioxonil, and (D) difenoconazole, and use of the compositions in agriculture, especially for treatment of plant propagation material.

The present invention provides a synergistic insecticidal composition comprising chlorfenapyr, fipronil, and at least one more insecticide. The present invention further provides a method for preparation of the insecticidal composition and use thereof. The insecticidal composition of the present invention is effective against pests of different crops and serves as a useful tool for managing resistance. The composition has a broad spectrum, is environmentally safe, has a reduced dosage, and has a lower frequency of application than existing formulations.

The present invention belongs to the technical field of pesticides, and specifically relates to an insecticidal composition containing 4-(trifluoromethyl)nicotinamide, and an application thereof. The insecticidal composition includes an active ingredient A and an active ingredient B, wherein the active ingredient A is 4-(trifluoromethyl)nicotinamide, and the active ingredient B is selected from one or more of the following compounds: afidopyropen, formula (I), dimpropyridaz, formula (II), isoflualanam, fipronil, imidacloprid, thiamethoxam, avermectin, acephate and beta-cypermethrin. The composition has features such as reasonable components, good insecticidal effect, low administration cost, reduced application amount, crop safety, and reduced residue.

The invention discloses an environment-friendly root-puncture-resistant PVC (polyvinyl chloride) waterproof roll and a preparation method thereof. The environment-friendly root-puncture-resistant PVC waterproof roll comprises the following components in parts by weight: 50-70 parts of PVC resin; 15-30 parts of an environment-friendly plasticizer; 5-12 parts of a root puncture resistant agent; 2-5 parts of a calcium-zinc composite stabilizer; 10 to 20 parts of nano calcium carbonate; 3-8 parts of a flame retardant; 0.5 to 2 parts of an antioxidant; 0.3 to 1.5 parts of an ultraviolet light absorber; and 1-3 parts of a coloring agent. The environment-friendly plasticizer is adopted, the epoxidized soybean oil and the citrate plasticizer are compounded according to a specific proportion, the content of phthalate is remarkably reduced (smaller than or equal to 0.1%), and therefore potential threats to the environment and human health are reduced; the chemical root-resistant agent is selected from effective components such as fipronil and triazolone, the physical root-resistant material is a copper foil layer with moderate thickness or a polyester fiber reinforcement layer with enough gram weight, and the composite system can play double roles of chemical root resistance and physical root resistance at the same time, so that plant root systems are effectively prevented from penetrating through the waterproof layer.

The invention discloses fipronil missible oil and a preparation method thereof. Relates to the technical field of pesticide preparations. Comprising the following steps: stirring odorless kerosene and tributyl phosphate; adding nonylphenol polyoxyethylene ether, and stirring; adding dodecylbenzene sulfonic acid calcium salt, and stirring; adding polyoxyethylene nonylphenol phosphate, and stirring; and finally, adding fipronil, and continuously stirring to obtain the fipronil missible oil. The finished product is low in odor, clear, stable and good in water dilution and emulsification; through sand-based bioassay, under the same soil target concentration (g / g), the LC50 of the missible oil for 12 hours and 24 hours is obviously lower than that of the missible oil sold in the market, and the missible oil has a better lethal effect.

The invention relates to the technical field of veterinary drugs, and particularly discloses a long-acting tick-repelling compound preparation which comprises the following components: a component A, a component B, a component C and a component D, the component A comprises the following components in percentage by weight: 0.3-0.7% of fipronil, 1.0-1.5% of permethrin, 25-35% of silicon dioxide and 0.05-0.15% of iron oxide red; the component B comprises the following components in percentage by weight: 12%-18% of polyacrylate colloid (medicinal grade), 4%-6% of castor oil polyoxyethylene ether, 1.5%-2.5% of azone and 1.5%-2.5% of absolute ethyl alcohol; wherein the mixing weight ratio of the component A to the component B is (1: 1.5)-(1: 2.5); through the synergistic effect of silica micropore adsorption and the polyacrylate colloid sustained-release film, the sustained release of the drug for 180 + / -5 days is realized, the drug application frequency is greatly reduced, the safety is remarkably improved, and the animal licking risk is reduced by adding menthol.

The invention discloses an environment-friendly and efficient cockroach-killing bait and a preparation method thereof, and belongs to the technical field of cockroach-killing bait preparation.The cockroach-killing bait can simulate the natural food effect of cockroaches through the combined action of brown sugar, maltose and fish meal protein, the eating amount of the cockroach-killing bait by the cockroaches is increased by means of the taxis of the cockroaches to saccharides, and therefore the cockroach-killing bait can be used for killing cockroaches. Imidacloprid is used for replacing fipronil, the toxicity of the cockroach killing bait is reduced, imidacloprid is used for playing a role of a nerve poison agent on cockroaches, inhibiting actions and promoting the cockroaches to move disorderly, strong pungent smell generated by fipronil is avoided, family use is facilitated, the enzyme inhibitor can inhibit cell enzyme production in cockroach bodies, and the cockroach killing bait can be used for killing cockroaches. And the penetrating agent can destroy the wax coat on the body surface of the cockroach and improve the penetration efficiency, so that the cockroach is difficult to generate resistance under the multi-direction and multi-target action, the killing efficiency of the cockroach is further improved, the toxicity is reduced, and the cockroach killing agent is environment-friendly and efficient.

The invention relates to the technical field of pesticide slow release, in particular to a fipronil-containing microcapsule suspending agent and a preparation method thereof. The preparation method of the fipronil-containing microcapsule suspending agent comprises the following steps: (1) preparing a copolymer fipronil dispersion liquid; (2) preparing a chitosan copolymer fipronil suspension; (3) preparing fipronil microcapsules; and (4) adding the emulsifying dispersant into the fipronil microcapsule, complementing to 100% by weight with water, and stirring to obtain the fipronil microcapsule suspending agent. The fipronil microcapsule suspending agent prepared by the invention moderately releases about 45-50% of fipronil in an initial stage and rapidly establishes an effective insecticidal concentration, and slowly releases the residual fipronil through a compact wall material in a later stage, the accumulative release rate reaches 92-95%, the action time of the fipronil is effectively improved, the stability of the pesticide effect is improved, and the fipronil microcapsule suspending agent has a good application prospect.

An insecticidal composition includes fipronil in an amount of less than 0.1 wt. %, at least one surfactant, at least one emulsion stabilizer, and at least one arthropod attractant, wherein the insecticidal composition has a viscosity of more than about 50 centipoises. The insecticidal composition has improved stability and prevents migration of fipronil into plastic packaging over time, such that the composition retains more than about 90% of fipronil when stored in a plastic packaging for 3 months or more at room temperature.

The present invention discloses an insecticide bait composition containing a piperic acid derivative compound. The compounded insecticide bait comprises active ingredients A and B, wherein A is a piperic acid derivative compound and B is one of fipronil, indoxacarb, dinotefuran, hydrazone, or imidacloprid. The weight ratio of A to B is 20:1 to 1:10. Because the piperic acid derivative compound is a brand-new insecticide ingredient with a novel mechanism of action, a good lethal effect, and no repellency to sanitary pests, the composition can delay the resistance of single insecticide baits, improve the control effect, and prolong the lasting effect.

The invention relates to the technical field of biochemical engineering, in particular to fipronil hapten and a preparation method thereof, artificial antigen, monoclonal antibody and application. The hapten has a chemical structure as shown in a formula I or a formula II. The invention also relates to an artificial antigen obtained by connecting the hapten and a carrier protein. The application comprises the following steps: (1) preparing a specific antibody for resisting fipronil or main metabolites thereof; (2) detecting a specific antibody resisting fipronil or main metabolites thereof; and (3) preparing a reagent for detecting a specific antibody resisting fipronil or main metabolites thereof. The hapten provided by the invention can expose common epitopes of fipronil and metabolites thereof to the greatest extent, can be used for preparing broad-spectrum specific monoclonal antibodies with uniform cross reaction rate and high sensitivity, and can realize high-specificity and sensitivity detection of fipronil or main metabolites thereof.

The present invention belongs to the field of waste gas treatment technology, and specifically relates to waste gas treatment equipment for the production of fipronil technical, comprising a purification box and a filter box, the purification box being located above the filter box, and a plurality of guide assemblies located inside the purification box. The guide assemblies include a guide plate, side baffles being fixedly mounted on both the inner and outer sides of the guide plate, and a plurality of diverter plates A and B being fixedly mounted on the outer wall of the guide plate, the diverter plates A and B being alternately arranged, with a guide cavity formed between the guide plate, the side baffles, the diverter plates A, and the diverter plates B. During waste gas purification, the spiral shape of the guide plate allows sufficient time for the purification liquid to react with the waste gas, effectively improving the purification effect. The diverter plates A and B diverter plates cause the waste gas to undergo multiple diversions, thereby increasing the contact area between the waste gas and the purification liquid, thereby more fully removing harmful substances in the waste gas.

The present application relates to the technical field of immunochromatographic analysis, and discloses a signal enhancer for a colloidal gold immunochromatographic rapid detection card and a preparation method thereof, the signal enhancer comprises a silver ion solution, a thiourea-ascorbic acid synergistic reducing agent, a pH buffer system and a surfactant stabilizing system, signal amplification is realized by catalytic deposition of silver nanoparticles on the surface of colloidal gold, the present application is simple to operate, is added at one time, and reaction is completed in 5-10 minutes; sensitivity is improved by 5-10 times, specificity is higher than 98%; stability is excellent, 12 months of storage at 4 DEG C; it is compatible with various colloidal gold rapid detection cards; cost is controllable, single detection is increased by 0.3-0.5 yuan, and the present application is especially suitable for super-sensitive detection of small molecule substances in the field of food safety, such as detection limit of malachite green of 0.1 microgram per liter, detection limit of fipronil of 0.5 microgram per liter, and the application range of the colloidal gold immunochromatographic rapid detection card is significantly expanded.

The utility model relates to the technical field of fipronil detection, and discloses a single quadrupole mass spectrometer for fipronil detection, which comprises a base, the top of the base is fixedly provided with a box body, the top of the base is slidably connected with a sliding plate, and the top of the sliding plate is fixedly provided with a fixed shell. By pulling a sliding plate and a handle, the handle drives a pull rod to move, then the pull rod pulls a steel wire rope to move, one end of the steel wire rope moves, the other end of the steel wire rope drives a fixing pin to move upwards, and the fixing pin is separated from a circular groove in the inner wall of the base; at the moment, the sliding plate can slide on the top of the base, the sliding plate is pulled to drive the fixing pin and the fixing shell to move, when the fixing pin reaches another circular groove in the inner wall of the base, the spring rebounds, the fixing pin is fixed, and then the sliding plate is fixed; and the fixed shell is separated from the box body.

The invention provides a silica gel foam sealing material capable of preventing termite gnawing and a preparation method of the silica gel foam sealing material, and belongs to the technical field of polymer sealing materials. The raw material formula of the silica gel foam sealing material is as follows: vinyl silicone oil, a reinforcing filler, a flame-retardant filler, a contact insecticide, a bait, an odorant, a structure control agent, an inhibitor, a platinum catalyst, a foaming agent, hydroxyl silicone oil and hydrogen-containing silicone oil. Wherein the contact insecticide is one or more of pyrethroids, neonicotinoids, phenyl pyrazoles, boric acid, glycine, erythritol and fipronil; the bait agent is one or more of diatomite, talcum powder, capsaicin, dihydrocapsaicin and denatonium benzoate; the odorant is one or more of camphor oil, peppermint oil, limonin, limonene, citral, capraldehyde, octanal and nonanal. The silica gel foam sealing material disclosed by the invention has excellent flame retardant property, mechanical property and ant gnawing resistance, and the integrity of the sealing material can be well protected.

This invention relates to a method of controlling, limiting or preventing an infestation of a plant by Oomycetes, which comprises applying to propagation material of said plant, a pesticidal combination comprising a phosphorus-based compound as active ingredient A, and an active ingredient B selected from acibenzolar-S-methyl, fludioxonil, fluxapyroxad, inpyrfluxam, mefentrifluconazole, prothioconazole, sedaxane, triticonazole, oxathiapiprolin, fluoxapiprolin, azoxystrobin, difenoconazole, fluopyram, ipconazole, metyltetraprole, silthiofam, dimethomorph, thiophanate-methyl, natamycin, benzovindiflupyr, pydiflumetofen, picarbutrazox, isocycloseram, cyclobutrifluram, broflanilide, thiamethoxam, imidacloprid, clothianidin, cyantraniliprole, chlorantraniliprole, tetraniliprole, fipronil, and any mixture thereof.

FIELD: veterinary science.SUBSTANCE: used to treat dermatitis of parasitic etiology in carnivores. The medications selamectin and fipronil are applied to the skin between the shoulder blades at the base of the animal’s neck. After which they are treated with a solution of ethyl alcohol. Next, using a sprayer, the surface is treated with electrochemically activated water with an acidic fraction with a pH of 2.0 in the amount of 20 ml per 15–20 cm2 for 15–18 s from a distance of 15–18 cm, then held for 40 min, after which the surface is treated with electrochemically activated water with an alkaline fraction with a pH of 9.0 in the amount of 20 ml per 10–12 cm2 for 15–18 s from a distance of 15–18 cm. The treatment is carried out twice a day until the skin heals.EFFECT: method provides for combined highly effective eradication of ectoparasites and suppression of pathogenic microflora with simultaneous acceleration of regeneration of damaged tissues due to the synergistic action of systemic-contact insectoacaricides and sequential local treatment of affected areas of the skin with electrochemically activated solutions with regulated acid-base balance.1 cl, 1 dwg

The application provides an anti-termite sealing material of silica gel foam and a preparation method thereof, and belongs to the technical field of polymer sealing materials. The raw material formula of the anti-termite sealing material of silica gel foam is as follows: vinyl silicone oil, reinforcing filler, flame-retardant filler, contact killing agent, bait agent, odor agent, structure control agent, inhibitor, platinum catalyst, foaming agent, hydroxyl silicone oil and hydrogen-containing silicone oil; wherein the contact killing agent is one or more of pyrethroid, neonicotinoid, phenylpyrazole, boric acid, glycine, erythritol and fipronil; the bait agent is one or more of diatomite, talcum powder, capsaicin, dihydrocapsaicin and denatonium benzoate; and the odor agent is one or more of camphor oil, peppermint oil, limonin, limonene, citral, decanal, octanal and nonanal. The anti-termite sealing material of silica gel foam has excellent flame-retardant performance, mechanical performance and anti-termite biting performance, and can well protect the integrity of the sealing material.

The utility model discloses a fipronil original drug production chemical reaction kettle which comprises a kettle body, a first gear is arranged at the bottom of the kettle body, a supporting frame is arranged on the outer side of the kettle body, a rack is arranged on the surface of the supporting frame, the first gear is meshed with the rack, a supporting seat is arranged at the top of the kettle body, a positioning block is arranged at the top of the supporting seat, and the first gear is meshed with the positioning block. An electric lead screw is arranged on the outer side of the positioning block and used for driving the positioning block and the supporting base to move, and a first motor and a second motor are arranged on the top of the supporting base. Through the arrangement of the supporting seat, the electric screw rod and the supporting frame, the electric screw rod can push the positioning block and the supporting seat to move, the whole kettle body is driven to move on the surface of the supporting frame through meshing of the first gear and the rack, and the inclination angle of the kettle body is adjusted; the original medicine in the kettle body can be overturned to adjust the position in the production process, so that the original medicine is prevented from being deposited and accumulated, and the reaction efficiency and speed are improved.

The utility model relates to the technical field of chemical engineering, and discloses a fipronil refining and crystallizing device which comprises a shell, a fixing plate is fixedly connected to the right side of the outer wall of the shell, a vacuum pump is fixedly connected to the top of the fixing plate, a top cover is fixedly connected to the top of the shell, and a waterproof shell is fixedly connected to the top of the top cover. A motor is fixedly connected to the inner wall of the waterproof shell, a first stirring rod is fixedly connected to the output end of the motor, a main gear is fixedly connected to the top of the outer wall of the first stirring rod, an auxiliary gear is connected to the outer wall of the main gear in a meshed mode, and a stirring tank is arranged on the inner wall of the shell. The vacuum pump is started to evacuate air to form a vacuum environment, the boiling point of a solvent is reduced, raw materials are fully dissolved in the solvent through the heating wire, the motor is started, the main gear and the auxiliary gear are matched to enable the second stirring rod to rotate and rotate along the inner wall of the inner gear ring, the dissolving time is shortened, and the crystallization process is advanced.

The invention discloses a device and method for detecting fipronil in egg powder, and relates to the technical field of egg powder detection.The device comprises a bottom plate, two vertical plates are fixedly connected to the upper side of the bottom plate, rotating shafts are rotationally connected to the outer sides of the two vertical plates, and a heating cavity is fixedly connected between the two rotating shafts; a fixed cylinder is fixedly connected to the inner side of the heating cavity, an inner container is arranged on the inner side of the fixed cylinder, a top cover is fixedly connected to the upper side of the fixed cylinder, a feeding port is formed in the upper side of the top cover, and a charging port is formed in the upper side of the fixed cylinder. According to the device for detecting fipronil in egg powder, through the arrangement of the bottom plate, the fixed cylinder, the inner container, the top cover, the motor, the control rod and the dispersion plate, the egg powder is conveniently dispersed after being introduced into the fixed cylinder, and through the rotating shaft, the sliding groove, the sliding block, the first inclined plate and the electric push rod, the fixed cylinder is conveniently controlled to shake repeatedly, so that the egg powder is uniformly distributed, and subsequent sampling detection is facilitated.

The invention relates to a solid molded body for external use against parasites on animals. The molded body of the invention includes, as active compounds, the combination of fipronil and bifenthrin. In addition, the insect growth regulators pyriproxyfen and methoprene may be added as additional actives.

Pesticidal mixtures comprising as active compounds A) the ethylsulfone compound of formula (I) and B) at least one further compound B selected from fipronil, lambda-cyhalothrin, bifenthrin, tefluthrin, alpha-cypermethrin, thiamethoxam, clothianidin, acetamiprid, imidacloprid, dinotefuran, tri-flumezopyrim, fenmezoditiaz, spinosad, spinetoram, abamectin, afidopyropen, indoxacarb; met-aflumizone, spiropidion, spidoxamat, chlorantraniliprole, cyantraniliprole, tetraniliprole, cyclaniliprole, broflanilide, isocycloseram; dimpropyridaz; and difenoconazole, prothioconazole, flutriafol, ipconazole, tebuconazole, mefentrifluconazole, triticonazole, fluoxytioconazole, metyltetraprole, azoxystrobin, trifloxystrobin, pyraclostrobin, sedaxane, penflufen, fluopyram, fluxapyroxad, pydiflumetofen, isoflucypram, cyclobutrifluram, oxathiapiprolin, fluoxapriprolin, metalaxyl, picarbutrazox, fludioxonil, thiophanat-methyl; methods and use of these mixtures for combating invertebrate pests such as insects, arachnids or nematodes in and on plants, and for protecting such plants being infested with pests, especially also for protecting plant propagation material as like seeds.