105 results about "Anthelmintic" patented technology

The present invention relates to the discovery of a novel endophytic fungus, Muscodor vitigenus, from the liana, Paullinia paullinioides. This fungus produces naphthalene under certain cultural conditions that has chromatographic and mass spectral properties that are identical to authentic naphthalene. In a preferred embodiment, the naphthalene in the gas phase of M. vitigenus is useful in the repellency of unwanted insect pests. The unique biological activity of the novel endophyte suggests a wide range of potential practical applications, particularly in the area of insect repellents, insecticides, antimicrobials, anthelmintics and vermicides.

The present invention provides for, inter alia, novel topical formulations comprising at least one 1-N-arypyrazole derivative and amitraz and to methods for treating, controlling, or preventing parasite infestations on mammals or birds The inventive formulations include spot-on, pour-on or spray formulations and may include a further ectoparasiticide, such as an IGR compound, an avermectin or milbemycin derivative, or a pyrethroid insecticides, and anthelmintics, such as benzimidazoles and imidazothiazoles. The inventive formulation provides a larger duration of parasite control at a faster rate of control. The inventive formula remains effective up to three months from the first application. Moreover, the inventive formulations prevent tick attachment to the animal, thereby providing protection against tick borne diseases. The ectoparasites which may be controlled, treated or prevented by the present invention includes ticks, fleas, mites, mange, lice, mosquitoes, flies and cattle grubs.

The present invention provides a method for preparing a pharmaceutical formulation containing ivermectin and a method and composition that can contain ivermectin plus tetrahydropyrimidines. An examples of a tetrahydropyrimidine includes pyrantel. A pharmaceutical formulation is provided for use in the treatment of helminthiasis of mammals, and particularly tapeworm, hookworm, roundworm and heartworm of domestic animals and farm animals. The present invention also provides a method of treating helminthiasis in mammals, which method comprises administering to the mammal in need thereof an anthelmintically effective amount of a pharmaceutical formulation of the invention.

The invention provides a powerful insect repellent for veterinary use and a preparation method thereof. The insect repellent comprises the following components in parts by weight: 5-8 parts of tripterygium wilfordii, 20-30 parts of radix sophorae flavescentis, 15-25 parts of the fruit of rangoon creeper, 10-15 parts of stone-like omphalia, 20-30 parts of rheum officinale, 10-15 parts of liquorice, and 10-15 parts of beta-cyclodextrin. Effective pharmaceutical ingredients of tripterygium wilfordii and active ingredients of liquorice are separated by using modern pharmacology, meanwhile, scientific composition and preparation are carried out by a modern traditional Chinese medicine principle, stone-like omphalia powder, radix sophorae flavescentis powder, rangoon creeper powder and rheum officinale powder are mixed with the effective pharmaceutical ingredients of the tripterygium wilfordii and the effective ingredients of the liquorice, and the pelleting is carried out through beta-cyclodextrin. Multiple insect repellent ingredients are contained in the prescription to achieve the purpose of thoroughly clearing away protozoon and parasite in vitro and vivo. The insect repellent can be used in the aspects of not only livestock and poultry treatment and prevention but also aquatic parazoon prevention, is simple in production process, definite in treatment effect, and low in cost, and has a certain social application prospect.

The invention relates to an insectifuge and particularly relates to an environment-friendly insectifuge and a preparation method thereof. The environment-friendly insectifuge is prepared by garlic, pepper, melia azedarach fruit, dark plum fruit, Chinese torreya seed kernel, betel nut, radix sophorae flavescentis and antifeverile dichroa root. The insectifuge adopts natural plant fruits, is wide in material source, does not generate insecticide resistance in the plant body, has no harmful residue or obvious toxic and side actions and is an organic 'green' insect-repellent health-care product.

The invention provides an antiviral compound preparation for fish. The compound preparation composition comprises microparticles containing macrolide anthelmintic, as well as two or more than two of bithionol, praziquantel, diflubenzuron, triflumuron, pyriproxyfen, sulfur powder, salicylanilide, organic phosphorus, benzimidazole, pyrethroid, triazine, tetramisole anthelmintic, sulfonamides, anticoccidial drugs and Chinese herbal medicine anthelmintic, wherein the microparticles containing macrolide anthelmintic are microspheres or microcapsules composed of biodegradable or non-biodegradable carrier materials and macrolide anthelmintic, and the content of the macrolide anthelmintic in the microparticles is 0.1-50%. The compound preparation provided by the invention can not only expand the insecticidal spectrum, but also effectively improve the anthelmintic activity and reduce toxicity so as to ensure safer use.

The invention discloses a method for decoloring imidazole anthelmintics. The method sequentially comprises the following steps of: (1) dissolving the imidazole anthelmintics into acid, and stirring until the solution is clear; (2) adding a reducing decoloring agent into the dissolved clear liquid, heating to 40-55 DEG C, and carrying out heat preservation for 1-2 hours; and (3) adding a solvent into the decolored liquid, fully stirring, cooling to the room temperature, and then separating out crystal; and finally, centrifugally washing and drying to obtain the product. The method has the advantages that the reducing decoloring agent is used for decoloring the imidazole anthelmintics, so that the disadvantages of the traditional activated carbon decoloring agent can be overcome; and the method is good in effect, convenient to operate and suitable for industrial popularization and application.

The present invention relates to a non-aqueous composition that comprises a permeation enhancer such as a terpene, for delivering an active ingredient transdermally. The composition comprises at least on one active ingredient, a terpene, and a solvent, such as a non-hydroxyl containing solvent, non-heterocyclic ester solvent and/or a tripropylene glycol alkyl ether. The composition can be used to deliver a range of actives, such as anthelmintics. The present invention provides a platform composition and can be used to deliver a wide variety of active ingredients and combinations thereof transdermally to mammals.

The present invention discloses a duck feed added with an anthelmintic active ingredient. The duck feed is added with Chinese medicinal herbs and has a certain effect on the prevention and treatment of diseases and pests of duck. The duck feed is prepared by grinding and mixing feeds of cereals, bran, soybean cake, peanut meal, freshwater shrimp powder, blood worm powder, etc.; adding various additives, such as bone meal, a plurality of vitamins, etc.; then adding crushed Chinese medicinal herbs of quisqualis, fruiting body of omphalia, betel nuts, pumpkin seeds, etc., wherein the use amount of the herbs in each kilogram feed are: 0.6-1.2 grams of quisqualis, 0.4-0.7 grams of fruiting body of omphalia, 0.8-1 grams of betel nut, and 4-7 grams of pumpkin seeds; and mixing above materials uniformly.

The invention discloses a breeding method for a piglet and relates to the field of pig raising. The method comprises the following steps: (1) heat preservation and lactation; (2) iron supplement; (3) feeding and feed supplement; (4) weaning breeding; and (5) breeding of a growing-finishing pig. According to the invention, the ratio of feed to water of complete batched feed can promote easy digestion of the piglet after feeding; the use of anthelmintics like anthelmintic essence and tetramisole for expelling of in-vivo and in-vitro parasites of the piglet before transferring of the piglet can effectively reduce the infection rate of the piglet, enhance resistance of the piglet and thus improve the quality of pork; due to arrangement of microbial fermentation bedding materials in a growing-finishing pig house, setting of the net area, composition and proportion of the microbial fermentation bedding materials and decomposition and fermentation of soil microorganism coenobium, organic substances in manures and urine of the piglet are converted into odorless and harmless substances and bacterium protein, and reproduction and growth of numerous microorganisms provide a plurality of organic bacterium protein for the piglet to eat; therefore, the quality of the pork is improved, production of pollutants is reduced, and great market potential and broad prospects are obtained.

The present invention relates to veterinary or pharmaceutical antiparasitic formulations which may comprise a macrocyclic lactone, one or more alcohol cosolvents and an oil wherein the crystallization of the macrocyclic lactone is minimalized. This invention also provides for, inter alia, antiparasitic formulations for the treating, controlling and preventing of endo- and ectoparasite infections in warm-blooded animals, such as livestock.

An antiparasite for eel is prepared from 4 Chinese-medicinal materials including quisqualis fruit, cyrtomian rhizome, stemona root, etc.

Compounds, compositions, methods, materials, and transgenic animals for antihelmintic purposes are described.

The invention discloses a compound preparation for expelling and killing endobiotic eelworms epizoic fleas, lice and other parasites of cats and dogs. The compound preparation adopts the formula comprising pyrethrin having a specific effect for fleas and macrolide anthelmintics having specific effects for mites, ticks, lice and eelworms, and has the remarkable characteristics that the compound preparation is convenient for use and the infection from parasites such as fleas and lice of cats and dogs can be effectively prevented; and the medicament is safe for use and has no adverse reaction after being administrated by animals.

The present invention discloses a pig feed added with an anthelmintic active ingredient. The pig feed is added with Chinese medicinal herbs and has a certain effect on the prevention and treatment of diseases and pests of pig. The pig feed is prepared by grinding and mixing feeds of cereals, corn, soybean meal, cavings, sorghum bran etc.; then adding various additives, such as a plurality of vitamins, etc.; then adding crushed Chinese medicinal herbs of quisqualis, fruiting body of omphalia, betel nuts, pumpkin seeds, etc., wherein the use amount of the herbs in each kilogram feed are: 10-15 grams of quisqualis, 6-10 grams of fruiting body of omphalia, 15-20 grams of betel nut, and 60-80 grams of pumpkin seeds; and mixing above materials uniformly.

The invention discloses a niclofolan-contained compound sustained-release animal parasiticide, aiming at solving the problems of parasitic mixed infection or multiple infection of the livestock and the poultryin the livestock and poultry cultivation. The niclofolan-contained compound sustained-release animal parasiticide comprises the following raw materials by weight percent: 10-50 percent of niclofolan, 3-20 percent of parasite repellent, 10-40 percent of sustained-release matrix material, and the balance of adhesive. The parasite repellent is one of the ivermectin, the avermectins and the albendazole; the sustained-release matrix material is the hydroxypropyl methyl cellulose; and the adhesive is polyvinylpyrrolidone. The niclofolan-contained compound sustained-release animal parasiticide has broad spectrum and good sustained-release effect, can repel different age groups of various parasite larvae parasitized on the livestock and the poultry by over 97.5 percent, is convenient to use and saves the animal treatment cost. The niclofolan-contained compound sustained-release animal parasiticide can prevent the livestock and the poultry against spring weakness death and weight losscaused by the parasites, thereby being an ideal medicament of preventing the livestock and the poultry like the cattle and the sheep against the parasites.

The present invention provides a veterinary anthelmintic composition that includes: at least 10% w/v of a benzimidazole anthlemintic; and b) a water-immiscible solvent system, which comprises a lactone solvent, an essential oil, and surfactant.

The invention discloses a pet food additive which comprises the following components in parts by weight: 20-60 parts of chitosan, 15-35 parts of calcium ion powder, 1-5 parts of coenzyme, 2-10 parts of toosendanin, 2-10 parts of a white willow bark extract, 3-15 parts of a yucca extract, 3-15 parts of an amur cork tree bark extract, 5-25 parts of hypericin, 5-25 parts of a basil extract and 1-5 parts of animal proteins. The pet food additive provides a functional health-care formula containing mineral elements and biological agents, has healthy and pure natural characteristics by using reasonable compatibility of ionized mineral elements and biological extraction components, and can not cause any side effect or disease hazard when being eaten by a pet dog. The additive is remarkably beneficial to building the body of the pet in the growth process, vaccination is not needed in a strong body, infection of pathogenic bacteria on the pets can be resisted generally, the possibility of skin diseases is reduced or avoided, parasite ova do not survive in the body, and vermifuge is not needed to be taken. In addition, odor of excrements can be lightened under the effect of increasing beneficial bacteria in the intestines.

The invention relates to compositions and methods for promoting production gains in animals, and of enhancing the efficacy of therapeutic agents. The gains are achieved through reduction in stress, including through the use of antistress agents. Compositions comprising therapeutic agents such as anthelmintics, and antistress agents are provided.

The present invention relates to a new compound of formula (I) wherein the variables have the meaning as indicated in the claims; or an enantiomer or salt thereof. The compounds of formula (I) are useful in the control of parasites, in particular endoparasites, in and on vertebrates.

The invention relates to a preparation method of aquatic animal insect repellent, comprising the following implementation steps: (1) weighing the following bulk pharmaceutical chemicals in parts by weight: 200-500 parts of artemisia apiacea, 100-200 parts of antipyretic dichroa and 100-200 parts of granatum; (2) adding water according to the total amount ratio of the bulk pharmaceutical chemicals: 1: 8-12; soaking for 30min by hot water at the temperature of 45 DEG C; decocting according to the conventional method; decocting for 40min by slow fire after boiling for the first time; filtering; decocting for 30min by slow fire after the filter residue boils with 6 times of added water; combing the filter liquor and filtering; concentrating the filter liquor at the temperature of 40-50 DEG C to the condition that the relative density is 1.05; (3) adding alcohol with weight concentration of 95%, leading the alcohol content in final concentration to be 60%, stirring, and standing for 24h; (4) filtering, recovering the alcohol; adding distilled water solution, concentrating the water solution at the temperature of 40-50 DEG C to the condition that the relative density to be 1.05-1.20; and (5) cooling the concentrated solution to room temperature, and subpackaging into 250ml/bottle. The preparation method is simple and effective, insect expelling Chinese herbal medicine is a drug for preventing and curing parasites in the body or out of the body of the cultivating aquatic animals, is harmless and protects the environment, and has obvious preventing and curing effects.