1535results about "Veterinary instruments" patented technology

A system suitable for collecting and transporting urine away from the body of a person or animal may include an assembly having a fluid impermeable casing having a fluid reservoir at a first end, a fluid outlet at a second end, and a longitudinally extending fluid impermeable layer coupled to the fluid reservoir and the fluid outlet and defining a longitudinally elongated opening between the reservoir and the outlet. The assembly can further include a fluid permeable support disposed within the casing with a portion extending across the elongated opening, and a fluid permeable membrane disposed on the support and covering at least the portion of the support that extends across the elongated opening, so that the membrane is supported on the support and disposed across the elongated opening. The assembly can further include a tube having a first end disposed in the reservoir and a second, fluid discharge end.

A veterinary incubator features a modular hygienic design, with a ceramic infrared heating element. The ceramic infrared heating element heats a puppy more deeply and can be tailored to the specific condition of the puppy, allowing for better processing of colostrum and food—leading to a better weight gain, a stronger immune system and eyes opening sooner than conventional incubators with puppies from the same litter. The veterinary incubator can be fully disassembled with 100% user replaceable modular components to allow for more effective disinfecting and elimination of service calls. The veterinary incubator creates a microenvironment that compliments a small animal's ability to seek out warmer and cooler parts of their environment to regulate body temperature and can be adjusted to allow for only good choices based upon the small animal's condition.

A bioenergy generator to increase the life force of a biological system is provided. The bioenergy generator includes fine pieces of natural stone, fine pieces of natural sand, fine pieces of metal, water and a supporting material operable to hold the natural sand, the natural stone, the metal, and the water together. Uses of the bioenergy generator are also provided, in particular, to enhance stem cell production.

A system suitable for collecting and transporting urine away from the body of a person or animal may include an assembly having a fluid impermeable casing having a fluid reservoir at a first end, a fluid outlet at a second end, and a longitudinally extending fluid impermeable layer coupled to the fluid reservoir and the fluid outlet and defining a longitudinally elongated opening between the reservoir and the outlet. The assembly can further include a fluid permeable support disposed within the casing with a portion extending across the elongated opening, and a fluid permeable membrane disposed on the support and covering at least the portion of the support that extends across the elongated opening, so that the membrane is supported on the support and disposed across the elongated opening. The assembly can further include a tube having a first end disposed in the reservoir and a second, fluid discharge end.

A microminiature insect smell induction and smell selection behavior observation device is characterized in that a smell induction device comprises a feeding chamber (1) and connecting pipes connected to the two ends of the feeding chamber (1), and the outer sides of the connecting pipes are connected with a smell storage chamber; air holes (15) are formed in the top of the feeding room (1), and a solution delivery device is arranged on the front; each connecting pipe is composed of a high-density sponge hollow sealing plug and a plastic sleeve with one end open and the other end provided with a breathable gauze element. The smell storage chamber is composed of a smell storage chamber body and a closed silica gel plug or a hollow silica gel plug, the two ends of the smell storage chamber body are open, and a breathable gauze is arranged in the center in the smell storage chamber body to prevent the trichogramma ovipositor from touching smell substances. The device is simple in structure, is suitable for smell research of trichogramma, has the advantages of high efficiency and labor saving, and can obviously improve the experiment efficiency.

Systems and methods for detecting lameness in a limb of an animal using a machine learning model are described herein. In an implementation, a system receives first data measurements from a sensor device attached to the animal, where the first data measurements represent measurements associated with gait of an animal. Start and stop times are determined for movement events identified from the first data and the movement events are stored. A first machine learning model is used to generate levels of gait asymmetry using the movement events as input. The first machine learning model is a model trained to predicts levels of gait asymmetry based on movement data. Upon generating the levels of gait asymmetry, one or more treatment recommendations are generated based on the levels of gait asymmetry. The one or more treatment recommendations and levels of gait asymmetry are displayed on a client computing device.

The invention discloses a mouse spinal cord flexible electrode and a stimulation parameter optimization method, and relates to the technical field of parameter optimization. The mouse spinal cord flexible electrode comprises a soluble insertion layer, a gradient substrate layer, spinal cord anastomosis ribs, a conductive snakelike net, a hemispherical touch dot matrix, a microfluidic layer, an optical waveguide layer and a top packaging layer; the soluble insertion layer is photo-crosslinked PEG-DMA with the thickness of 5-25 m, the Young modulus is kept within the range of 0.8-1.5 GPa before implantation, and the soluble insertion layer is hydrolyzed in cerebrospinal fluid within 0.5-3 hours after implantation and completely falls off; the spinal cord anastomosis rib comprises an expandable S-shaped folding structure arranged on the upper surface of the gradient substrate layer, the distance between every two adjacent ribs ranges from 80 m to 200 m, the height of the folded state is not larger than 15 m, the height of the unfolded state ranges from 15 m to 40 m, and the spinal cord anastomosis rib is used for forming a cerebro-spinalfluid bypass groove extending in the longitudinal direction of the spinal cord on the surface of the dura mater. According to the invention, the positioning precision, safety and long-term efficiency of mouse spinal cord electrical stimulation can be effectively improved.

The invention belongs to the technical field of biotechnology and animal models, and discloses a double-person-derived mouse model for simulating a tumor immune microenvironment and a construction method and application thereof. The method comprises the following steps: firstly, pretreating NSG immunodeficient mice by adopting low-dose whole-body irradiation in combination with double-antibody targeted bone marrow depletion, and transplanting CD34 + hematopoietic stem cells from the same human donor to complete human immune system reconstruction; separating tumor primary cells, tumor-related fibroblasts and tumor vascular endothelial cells of the same donor, performing three-dimensional co-culture to obtain homologous human tumor organs, and performing in-situ inoculation to immune reconstruction mice to obtain a target model. The core defects of MHC mismatching, low immune reconstruction efficiency, poor tumor immune microenvironment simulation degree, low clinical consistency and the like of an existing model are overcome, and the method can be used for tumor immune treatment drug screening, microenvironment mechanism research and personalized tumor treatment scheme verification.

The invention discloses a method for researching the repairing effect of low-pressure and low-oxygen exercise on waist polyfidus injury, which comprises the following steps: S1, selecting and grouping experimental animals: selecting healthy adult rats, and randomly dividing the healthy adult rats into a plurality of experimental groups including a conventional exercise group, a low-pressure and low-oxygen exercise group, a low-pressure and low-oxygen treatment group and a control group; s2, setting a low-pressure and low-oxygen exercise environment: simulating a high-altitude environment by using a low-pressure oxygen cabin; the treadmill is used for rat running exercise; and S3, exercise plan implementation: performing exercise training on all the rats in the experimental group on the five-channel running machine. According to the invention, exercise training is carried out in a low-pressure and low-oxygen environment, so that a new physical intervention means is provided for rehabilitation treatment of waist muscle injury; researches show that movement under low-pressure and low-oxygen conditions is beneficial to acceleration of regeneration and repair processes of muscular tissues, which is crucial for rapid recovery of normal functions after acute or chronic waist injury.

The invention discloses a humanized osteoporosis mouse model and a construction method thereof, and belongs to the technical field of biotechnology and animal models. The invention aims at the core defects of large species difference, insufficient humanization degree, low pathological simulation degree, unstable phenotype and the like of the existing osteoporosis model. The humanized osteoporosis mouse model is constructed through five core steps of experimental animal pretreatment, collagen-nano hydroxyapatite bionic scaffold preparation and cell pre-implantation, immune-bone metabolism double-derived system construction, progressive osteoporosis induction and model identification and verification. According to the method, double-person origination of immune and bone metabolism systems is realized for the first time, the colonization rate and survival time of human cells are greatly improved, the pathological process of clinical postmenopausal osteoporosis is accurately simulated, the phenotype of the model is stable and uniform, the reactivity matching degree with clinical drugs is high, and the method can be widely applied to research and development of anti-osteoporosis drugs and research of pathological mechanisms.

The invention discloses wearable pet multifunctional physical therapy health equipment and a use method thereof. The wearable pet multifunctional physical therapy health equipment comprises a biocompatible flexible substrate and wearing system, an intelligent moxibustion warm physical therapy module, a multifunctional phototherapy module, a bionic micro-vibration massage module, a vital sign real-time monitoring system, an intelligent control and energy system and an omnibearing safety protection system. A biocompatible flexible substrate and a wearable system are adopted as carriers, multiple modules such as intelligent moxibustion warm physical therapy, multifunctional phototherapy, bionic micro-vibration massage and vital sign real-time monitoring are integrated, cooperative operation is achieved through intelligent control and an energy system, and meanwhile an all-around safety protection system runs through all the time. The integrated design breaks through the limitation that traditional pet physiotherapy equipment is single in function. The device has the core advantages that the accuracy of cross-species treatment is improved, the concealment of the treatment process is guaranteed, and human-pet-medical collaborative management is realized.

The utility model belongs to the technical field of livestock breeding, and particularly relates to a body surface disinfection cage for animal husbandry and veterinary surgeons, which comprises a shell, a liquid storage tank, a hose and a telescopic rod, and further comprises an air drying mechanism, a cleaning mechanism, a sliding chute, a circular telescopic sliding chute and a moving mechanism, the circular telescopic sliding grooves are formed in an extension rod of the telescopic rod, the two circular telescopic sliding grooves are symmetrical, the sliding grooves are formed in the two ends of the inner space of the shell, the moving mechanisms are installed on the sliding grooves and the circular telescopic sliding grooves, and the cleaning mechanisms are installed on the moving mechanisms; through cooperation of a sliding groove, a circular telescopic sliding groove and a moving mechanism, it is guaranteed that the cleaning mechanism can conduct all-around cleaning and disinfection on the body surface of an animal, the animal is prevented from catching a cold in the air drying process by arranging an air drying mechanism, and the cleaning effect of the device is guaranteed by arranging a brush head.

The invention provides an application of a spleen T lymphocyte exosome in construction of a depression animal model, a stress rat spleen T lymphocyte exosome is injected into a mouse body to construct the depression animal model, and the depression animal model can be used for depression drug screening, drug efficacy evaluation or diagnosis, and can be used for treating depression. And the method can also be used for researching and revealing pathogenesis of depression. The invention also proves that the IL4 / IL4R alpha signal channel and the BDNF signal channel play an important role in depression through experiments. The invention has important significance for clinical research of depression.

The invention relates to a lymphatic system regulation and control method and application. A lymphatic system modulator and / or a physical stimulus is provided to the subject to modulate the lymphatic system. The method provided by the invention is applied to organisms and can effectively improve the circulation function of a lymphatic-like system in a biological brain, so that an effective strategy is provided for treatment of brain function diseases.

The invention discloses a laboratory mouse temporomandibular joint cavity injection method and device based on ultrasonic guidance, and relates to the technical field of laboratory mouse experiments.The device comprises a supporting column, a first cantilever arranged on the supporting column, an external auditory canal positioning piece arranged on the first cantilever, and a second cantilever arranged on the first cantilever in a sliding mode, the second cantilever can rotate around the end, close to the first cantilever, of the second cantilever, and the second cantilever is used for being parallel to the orbital ear plane of the laboratory mouse; the carrying mechanism is arranged on the second cantilever in a sliding mode, and the carrying mechanism is used for driving the ultrasonic probe and the injector to move to the position of the articular cavity. Injection of the joint cavity of the laboratory mouse is guided based on the image collected by the ultrasonic probe, the needle inserting position, angle and depth of the injector can be observed and adjusted in real time, and compared with blind puncture in the prior art, the success rate of injection can be greatly increased, the number of times of puncture attempts can be reduced, and meanwhile the uniformity of laboratory mouse samples is effectively improved.

To provide an oxygen concentration adjusting device capable of performing proper oxygen therapy by adjusting the oxygen concentration of oxygen gas from an oxygen source fed into a cage, rather than adjusting the oxygen concentration by a gap opened in the cage. [Solution] An oxygen concentration adjusting device 12 supplies oxygen gas, adjusting the oxygen concentration of the oxygen gas to supply oxygen gas with an optimum oxygen concentration. Here, the oxygen concentration of the oxygen gas is controlled by a needle valve 12A that can vary the oxygen flow rate of the oxygen gas, and the oxygen gas is supplied to a cage 14 housing a small animal A or to an anesthesia machine.

The pre-filled microneedle injector comprises a needle cylinder, a piston and a needle head, the needle cylinder is of a hollow structure, a limiting ring is arranged at the open end of the needle cylinder, the piston extends into the needle cylinder from one side of the limiting ring and can move up and down in the needle cylinder, a rubber ring is arranged at the bottom end of the piston, and a pushing handle is arranged at the top of the piston; the needle head is fixed to the side, away from the limiting ring, of the needle cylinder and comprises a connecting part and needle tubes, the connecting part extends out of the needle cylinder, and at least one needle tube is embedded into the connecting part in an in-line mode. The syringe is used for injection of biological macromolecular medicine preparations and complex preparations, especially mRNA vaccines or medicine preparations needing to be pre-filled for micro-injection, the hydrophilic film on the inner wall of the needle cylinder enables biological macromolecular medicines such as the mRNA vaccines or the medicine preparations to be stably stored, and the injection efficiency is improved. And through the limiting buckle, the pre-filled microneedle injector cannot leak in the transportation process or the storage process.

A fish handling unit for processing live fish is provided. Such fish handling unit includes an inspection system configured to inspect a plurality of live fish. A conveyor assembly transports the live fish to the inspection system. At least one robotic cell is in communication with the inspection system. The robotic cell has a controller configured to control operation thereof. An end effector is operably engaged with the robotic cell. The end effector interacts with the live fish moving along the conveyor assembly, based on information determined by the inspection system and received by the controller. The end effector may optionally be an integrated gripper and injection assembly capable of orientation and injection of the live fish. Associated devices and methods are also provided.

The invention discloses a transportation environment intelligent adjusting method and system for long-distance lateolabrax japonicus transportation, and relates to the technical field of long-distance lateolabrax japonicus safe transportation. The method comprises the steps that lateolabrax japonicus transportation characteristics are constructed according to the estimated transportation duration, the average size of lateolabrax japonicus, the number of lateolabrax japonicus and the water temperature; constructing an anesthetic dosage recommendation model, importing the transport characteristics of lateolabrax japonicus into the trained anesthetic dosage recommendation model, obtaining the recommended anesthetic dosage for lateolabrax japonicus transport, anesthetizing to-be-transported lateolabrax japonicus, collecting the temperature, water quality and oxygen concentration of a transport water body in the transport process, and evaluating the activeness of lateolabrax japonicus bodies. And generating an adjustment gradient based on the activeness to dynamically adjust the transportation water body environment, and additionally setting an emergency and an emergency plan library to process the transportation emergency. By optimizing water quality management, improving an oxygen supply system and introducing an intelligent monitoring and regulating means, dynamic regulation and fine management in the whole transportation process are achieved, and health and survival of lateolabrax japonicus in the transportation process are ensured.

The invention discloses a drug screening method based on endotoxin attack, and relates to the technical field of drug screening, in the process of drug screening by using an experimental animal, firstly, an experimental animal model with diseases is established, a certain dose of endotoxin is given to the experimental animal for a period of time after the model is successfully built, and then the experimental animal is subjected to drug screening. And establishing evaluation indexes by utilizing a mathematical formula, and comprehensively evaluating the effectiveness and the safety of the medicine. The evaluation indexes comprise an endotoxin attack survival rate, a survival disease control rate and a survival disease control index. The method can be applied to screening of drugs for treating different diseases, and a more scientific and reliable screening method is provided for research of preclinical drugs or treatment methods.

The invention provides a computer simulation method and device for determining the position of an electrode patch. The method comprises the following steps: acquiring a mouse simulation model, wherein the mouse simulation model is obtained by performing three-dimensional reconstruction on a mouse with a brain tumor; simulation electrode patch pairs are sequentially arranged at multiple pairs of candidate positions in the head area of the mouse simulation model, and simulation alternating electric signals are applied to the simulation electrode patch pairs; for each pair of candidate positions in the multiple pairs of candidate positions, recording an electric field intensity value of a simulation electric field established between the simulation electrode patch pairs by the simulation alternating electric signals when the simulation electrode patch pairs are arranged at the candidate positions; selecting a pair of candidate positions with the maximum electric field intensity value from the plurality of pairs of candidate positions as target electrode patch positions; and determining an electrode patch corresponding to the position of the target electrode patch according to the position of the target electrode patch.

The invention provides a method for evaluating the endotoxin adsorption performance of a hemoperfusion device, which comprises a construction method of an endotoxemia rabbit model and comprises the following steps: injecting a bacterial liquid containing bacteria into a rabbit once to generate endotoxin in the rabbit body, the type of the bacteria is escherichia coli, the injection dosage of the bacterial liquid is 0.1-2mL, the OD600 value of the bacterial liquid is 1.3-1.7, and the endotoxin is generated in the rabbit body. And injecting the bacterial liquid for at least 3h to obtain the endotoxemia rabbit model. The endotoxemia rabbit model is used as an animal model for evaluating the endotoxin adsorption performance of the hemoperfusion device, the influence of factors of an animal body on the endotoxin concentration can be eliminated, and the endotoxin adsorption performance of the hemoperfusion device can be accurately and objectively evaluated.

The invention relates to a continuous automatic injection device for fishery vaccines, wherein a conveyor belt of a conveying device is connected to the end of an arc-shaped slide groove; an arc-shaped arm of a rotary push device pushes young grass carp that quickly passes on the conveyor belt into a working position of the injection device through the action of a swing arm; an injection rotating bottom plate can be driven by a rotating bottom plate swing cylinder to swing left and right, and when the injection rotating bottom plate is closed, the fish body that slides in can be received, and when the injection rotating bottom plate is opened, the injected young grass carp falls from the opening of the rotating bottom plate to a collecting tank; multiple groups of injection devices are arranged along the length direction of the conveying device; a fish body shape scanning device is arranged at a fish entry position of the conveyor belt of the injection device, and the specification and shape data of the fish body are collected in real time, and the moving distance of the slide table is controlled by a decision system to drive the change of the position of the injection needle; a pressure plate swing cylinder is used to apply pressure to a thin pressure plate to adjust the pressure on the fish body.

The invention relates to the technical field of medical instruments, in particular to an electromagnetic needleless injector which comprises a shell, a nozzle assembly, a liquid storage assembly, a driving assembly and an intelligent control system. Firstly, a series excitation linear motor is adopted to replace a traditional needleless injector driven by a spring, and the problems that driving force is limited and elasticity is attenuated due to the spring are effectively solved. According to the series excitation linear motor, through excitation magnetic field coupling between the stator coil and the rotor coil in the motor, the rotor directly drives the plunger rod to do linear motion in the axial direction so as to complete injection, the structure is simpler, the direct drive type connection structure is adopted, the stability is higher, and force transmission is more accurate. In addition, an intelligent control system integrated in the needleless injector enables the needleless injector to be more intelligent, control precision is higher, operation is more convenient, the needleless injector can be wirelessly connected with a breeding cloud management system, rapid, accurate and painless injection of live pigs and other animals can be achieved, and breeding efficiency and injection safety are improved.

A camera-based optokinetic motor device (OMR) for assessing visual acuity in rodents, consisting of: a. a two-chamber structure consisting of: ◯ an outer rotating chamber with an inner surface of alternating black and white vertical stripes, designed to produce an optokinetic visual stimulus; ◯ an inner static chamber, which is transparent and centrally positioned within the outer chamber and configured to accommodate the test object, wherein the inner chamber contains a centrally arranged, non-rotating platform for placing the rodent; b. a motorized rotation mechanism, comprising: ◯ a stepper motor that is operationally coupled to the outer chamber to enable controlled rotation at a fixed and adjustable speed; ◯ a switch-controlled rotation direction system that enables bidirectional movement, allowing both clockwise (CW) and counterclockwise (CCW) rotation at a predefined speed of 10 revolutions per minute (rpm); c. a high-resolution imaging system, consisting of: ◯ a high-resolution (HD) camera positioned at an optimal height above the device to capture the rodent's movement response in real time; ◯ a motion tracking module, either software-based or hardware-integrated, to analyze and quantify the subject's spatial frequency threshold (SFT) in response to the moving stimulus; d. a closed test environment, consisting of: ◯ a non-transparent housing surrounding the dual-chamber structure, forming a closed box configuration approximately 45 cm long and wide and 30 cm high to minimize interference and distractions from external light; ◯ an internal white LED lighting system on the inner wall of the housing, which ensures uniform lighting conditions and thus guarantees the clarity of the recorded visual data; e. a data acquisition and processing module configured to: ◯ Record the video data received from the HD camera; ◯ Processing and analyzing rodent movement patterns using the rotating stimulus to determine the optokinetic reflex (OKR) and visual acuity response; ◯ Save and export the collected data for later statistical analysis.

The apparatus of the present invention serves to stun animals prior to slaughter, these being introduced with a gondola into a pit. On a sidewall of the pit is / are designed a gas module, preferably a plurality of gas modules. Each gas module comprises a gas introduction line having a multitude of pores through which an anaesthetic gas can flow laterally into the pit. The multitude of pores ensures a laminar inflow of the anaesthetic gas. The lateral laminar inflow of the anaesthetic gas avoids an increase in the stress of the animals being stunned, thus enabling humane stunning prior to slaughter. At the same time, the modular construction by means of the gas modules facilitates simple dimensioning of the gas introduction capacities required and also the construction and retrofitting of corresponding apparatuses.

The invention discloses a preeclampsia mouse model. The preeclampsia mouse model is constructed by the following method: (1) combining a female mouse with a male mouse; (2) in the middle stage of pregnancy, intragastric administration of hypoxanthine and oteracil potassium salt is carried out on the pregnant mouse for a period of time; the invention also discloses a construction method and application of the gene. The invention provides a novel preeclampsia modeling mode, hypoxanthine and oteracil potassium salt are combined for use, and the administration dosage and the administration mode of hypoxanthine and oteracil potassium salt are controlled, so that the serum uric acid level of a model mouse is stably increased, preeclampsia change occurs in the model mouse, and the model mouse can be used for treating preeclampsia. The stability, specificity and pathophysiology characteristics of the model are ensured to be similar to those of human preeclampsia, so that the uric acid-induced preeclampsia mouse model is successfully constructed. The uric acid induced preeclampsia mouse model provides a valuable tool for researching the pathogenesis of preeclampsia, evaluating a new treatment method and understanding the effect of serum hyperuricemia in preeclampsia.

A variable sensor system for non-contact vital sign monitoring of animals is described. Non-contact vital sign monitoring may involve correcting measured signals for reflectance and variations in distance between measurements. Non-contact vital sign detection may include temperature detection, and / or measuring cardiovascular and respiratory information. Embodiments are described using a non-contact variable sensor integrated with a weight scale, integrated with a drone, having a pan-tilt monitoring feature, integrated with a kennel, integrated with an automatic pass-fail interface, and including a medication dispensing control module.

The invention relates to the technical field of veterinary epidemic disease detection, and discloses a veterinary epidemic disease remote monitoring and intelligent diagnosis system, which comprises a multi-mode biosensor array including an implantable miniature biochip, a wearable flexible physiological monitoring patch and an environment sensing sensor cluster, the implantable miniature biochip is used for being implanted into a key tissue organ area in an animal body and collecting microscopic physiological data such as cellular metabolism signals and local immune reaction marker concentration in real time, and the wearable flexible physiological monitoring patch is used for being attached to the body surface of the animal. By means of the multi-mode biosensor array and the edge intelligent preprocessing unit, animal physiology and environment data are accurately monitored in real time. The multi-modal biosensor array covers the implantable miniature biochip, the wearable flexible physiological monitoring patch and the environment sensing sensor cluster, and can comprehensively collect in-vivo microscopic physiological data, body surface macroscopic physiological parameters and feeding environment information of animals.