396results about "Veterinary instruments" patented technology

A bioenergy generator to increase the life force of a biological system is provided. The bioenergy generator includes fine pieces of natural stone, fine pieces of natural sand, fine pieces of metal, water and a supporting material operable to hold the natural sand, the natural stone, the metal, and the water together. Uses of the bioenergy generator are also provided, in particular, to enhance stem cell production.

The invention belongs to the technical field of biotechnology and animal models, and discloses a double-person-derived mouse model for simulating a tumor immune microenvironment and a construction method and application thereof. The method comprises the following steps: firstly, pretreating NSG immunodeficient mice by adopting low-dose whole-body irradiation in combination with double-antibody targeted bone marrow depletion, and transplanting CD34 + hematopoietic stem cells from the same human donor to complete human immune system reconstruction; separating tumor primary cells, tumor-related fibroblasts and tumor vascular endothelial cells of the same donor, performing three-dimensional co-culture to obtain homologous human tumor organs, and performing in-situ inoculation to immune reconstruction mice to obtain a target model. The core defects of MHC mismatching, low immune reconstruction efficiency, poor tumor immune microenvironment simulation degree, low clinical consistency and the like of an existing model are overcome, and the method can be used for tumor immune treatment drug screening, microenvironment mechanism research and personalized tumor treatment scheme verification.

The invention discloses a humanized osteoporosis mouse model and a construction method thereof, and belongs to the technical field of biotechnology and animal models. The invention aims at the core defects of large species difference, insufficient humanization degree, low pathological simulation degree, unstable phenotype and the like of the existing osteoporosis model. The humanized osteoporosis mouse model is constructed through five core steps of experimental animal pretreatment, collagen-nano hydroxyapatite bionic scaffold preparation and cell pre-implantation, immune-bone metabolism double-derived system construction, progressive osteoporosis induction and model identification and verification. According to the method, double-person origination of immune and bone metabolism systems is realized for the first time, the colonization rate and survival time of human cells are greatly improved, the pathological process of clinical postmenopausal osteoporosis is accurately simulated, the phenotype of the model is stable and uniform, the reactivity matching degree with clinical drugs is high, and the method can be widely applied to research and development of anti-osteoporosis drugs and research of pathological mechanisms.

A variable sensor system for non-contact vital sign monitoring of animals is described. Non-contact vital sign monitoring may involve correcting measured signals for reflectance and variations in distance between measurements. Non-contact vital sign detection may include temperature detection, and / or measuring cardiovascular and respiratory information. Embodiments are described using a non-contact variable sensor integrated with a weight scale, integrated with a drone, having a pan-tilt monitoring feature, integrated with a kennel, integrated with an automatic pass-fail interface, and including a medication dispensing control module.

The invention discloses a construction method and application of a preeclampsia animal model based on an RASA3 target, and belongs to the technical field of biomedicine.The preeclampsia animal model is constructed by injecting Ad-RASA3 into a pregnant mouse and monitoring pathological indexes, related to preeclampsia, of the pregnant mouse. According to the method, the animal model with preeclampsia-like clinical symptoms can be stably induced, the abnormal change of the uterine spiral artery remodeling process can be systematically monitored, the method is high in operation controllability and model stability, and an effective tool can be provided for deeply researching the pathogenesis of preeclampsia and developing a novel diagnosis and treatment strategy.

The embodiment of the invention discloses a method and system for emission computed tomography for animal imaging. The method comprises the steps that a plurality of imaging animals are placed on a plurality of trays in preset placement postures, each tray is configured to place one imaging animal, each tray comprises a body part fixing part, and the body part fixing parts are configured to fix the preset placement postures of the imaging animals placed on the body part fixing parts; placing a plurality of trays on the supporting part of the multi-imaging animal fixing device; the multi-imaging-animal fixing device is placed in an animal cabin of scanning equipment, and emission computed tomography is carried out on multiple imaging animals at the same time.

The invention relates to the technical field of medical instruments, in particular to a veterinary venous indwelling needle fixing and protecting system and an anti-falling application method.The veterinary venous indwelling needle fixing and protecting system comprises a first neck sleeve, a second neck sleeve and a flexible sleeve fixedly connected between the first neck sleeve and the second neck sleeve, a gap is formed in the top end of the flexible sleeve, and a notch is formed in the inner end, close to the gap, of the flexible sleeve; a notch is formed in the outer wall of the flexible sleeve, an indwelling groove is formed in the position, close to the notch, of the outer wall of the flexible sleeve in a penetrating mode, a connecting belt is fixedly connected to the position, close to the indwelling groove, of the outer wall of the flexible sleeve, a pawl is fixedly connected to an inner belt of the connecting belt, a hook-and-loop fastener belt is fixedly connected to one end of the connecting belt, and fifth hook-and-loop fasteners distributed on the flexible sleeve adhere to the hook-and-loop fastener belt; according to the pet indwelling needle, the pawls of the connecting belt are meshed with the pawl grooves, secondary reinforcement is achieved in cooperation with the hook-and-loop fastener belt, and the breathable film sticker is matched for limiting, so that the indwelling needle is effectively prevented from shifting and falling off due to movement of a pet.

This disclosure features tissue storage, irrigation, and infusion media compositions, and methods of using such compositions, for example, the temporary storage of cells and tissues prior to implantation or re-implantation, or for wound irrigation, wound packing, surgical site irrigation, or intravenous infusion. The tissue storage, irrigation, and infusion media compositions disclosed herein are useful in a healthcare or veterinary setting.

The invention belongs to the technical field of construction methods of disease animal models, and particularly relates to a construction method and application of a renal syndrome hemorrhagic fever mouse model. According to the HTNV infected mouse model established by the method disclosed by the invention, the symptom of the experimental mouse is close to the clinical symptom of a severe hemorrhagic fever with renal syndrome after challenge, the complete lethality and repeatability are high, and the HTNV infected mouse model has the advantages of simple operation, low cost and high efficiency. The method can be used for research on the HTNV pathogenic mechanism and immune mechanism and research and development of antiviral drugs and vaccines, and has great application value for perfecting an HTNV full-chain prevention and control system.

The invention belongs to the technical field of biomedicine, and particularly relates to an animal model and a modeling method thereof. According to the method, the northwest dryness syndrome type sub-health animal model is successfully constructed, an open model evaluation mode is adopted, and the established model is evaluated through goodness of fit; furthermore, autumn pear syrup is used for indicating that the prescription corresponds to the syndrome. The northwest dryness syndrome type sub-health target model established by the invention can provide a stable and reliable research model for external dryness syndrome essence exploration, arid region sub-health prevention and treatment, drug effect and pharmacological mechanism research of traditional Chinese medicines, prescriptions and the like with body resistance strengthening and dryness moistening effects, health product research and development and the like. An open model evaluation mode is adopted, and the higher the goodness of fit is, the closer the model to the northwest dryness syndrome type sub-health target model is. The northwest dryness syndrome type square domain dryness evil sub-health rat model is more suitable for arid region sub-health status research, and the northwest dryness syndrome type autumn cause dryness evil sub-health rat model is more suitable for autumn moistening health care research.

This utility model relates to the field of medical equipment technology, and in particular to an animal vaccine injection booster device, comprising a first air chamber, a second air chamber, a piston assembly, and a gun body; the gun body has a first air chamber and a second air chamber, the first air chamber having a gas source inlet, a gas outlet, and a gas delivery outlet, the gas delivery outlet communicating with the second air chamber, and a control valve also being provided in the first air chamber; when the trigger of the gun body presses the control valve, the control valve blocks the connection between the gas delivery outlet and the gas outlet; when the trigger of the gun body is released, the control valve blocks the connection between the gas delivery outlet and the gas source inlet; the second air chamber has a piston assembly, the piston assembly including a piston and a firing pin, the firing pin being disposed on the piston, and an elastic element being provided between the piston and the firing pin output end of the second air chamber; the trigger is disposed on the grip part of the gun body, the grip part having a grip groove on the side near the trigger, and a thumb groove on the top side of the grip part away from the trigger. This utility model is easy to operate and has a good grip feel.

The utility model discloses an electric needleless injector for livestock. The electric needleless injector comprises a shell, a battery, a nozzle assembly, a liquid inlet pipe assembly, a liquid storage cavity, an adapter block, a motor, a rotating worm, a worm position measuring plate, a compression spring, a spring connecting rod, a piston fixing rod, a transmission bearing, a spring pressing plate, a buffering rubber mat, a liquid medicine push rod and a Hall sensor. The utility model provides three more optimized functional structures: (1) the trigger device is simpler and more practical: the trigger device can be triggered by only pressing the head, the trigger device can be pressed on an animal body when in use, and liquid flying caused by the fact that the trigger device is not attached to the epidermis can be prevented; (2) the liquid medicine, the medicine bottle and the like are more convenient to replace: the Luer taper of the medicine bag is directly sleeved during use, or the medicine tube is directly sleeved on the Luer taper when the self-made medicine bottle and the medicine cylinder are used; and (3) the power structure is more stable and simpler: the motor drives the worm to rotate and then drives the straight connecting rod to operate.

The utility model relates to a capsule dosing device for rhesus monkeys, which comprises a thick tube and a thin tube, the thin tube is movably mounted in the thick tube in a penetrating manner, and a claw-shaped clamp is arranged at the bottom of the thick tube; the claw-shaped clamp comprises mounting blocks, the mounting blocks are fixedly mounted on the left inner wall and the right inner wall of the thick pipe correspondingly, first springs are fixedly mounted at the bottoms of the two mounting blocks correspondingly, a movable block is fixedly mounted between the bottoms of the two first springs, and a connecting rod is movably mounted at the bottom of the movable block; and adjusting plates are movably mounted at the bottoms of the connecting rods. The capsule administration device for the rhesus monkey can prevent the rhesus monkey from crushing the capsule to influence the accuracy of the administration amount and the drug absorption, so that the success rate of capsule administration can reach 100%, the test quality is ensured, and effective reference is provided for clinical medication; and moreover, the possibility that the teeth of the rhesus monkey hurt people during capsule administration can be effectively avoided, and the safety of people is guaranteed to the greatest extent.

The invention belongs to the technical field of medical experimental animal models, and particularly relates to a construction method of a rabbit ear acne model for studying acne pathogenesis and drug curative effect. A healthy New Zealand large-ear white rabbit is selected, a testosterone solution is subcutaneously injected to induce endocrine disorder, oleic acid is smeared at an opening of an external auditory canal on the inner side of an ear, dermatobacterium acnes suspension is subcutaneously injected, and whether acne-like lesions such as erythema, papule and comedo appear on the skin of the ear or not is observed. The method is easy and convenient to operate, low in cost, good in repeatability, capable of simulating the pathological process of human acne and suitable for acne pathogenesis research and drug screening.

The invention provides a veterinary care cabin, which comprises a cabin body, a cabin cover, a cabin cover, a cabin cover, a cabin cover, a cabin cover, a cabin cover, a cabin cover and a cabin cover, and is characterized in that the cabin body is provided with an accommodating cavity for accommodating animals; the monitoring assembly is used for monitoring one or more vital sign parameters of the animal contained in the cabin body in real time; the environment assembly is used for regulating and controlling one or more environment parameters in the cabin body so as to regulate and control a parameter value of each environment parameter in the one or more environment parameters to a target parameter value configured for the environment parameter; the controller is configured to control the environment component to regulate and control the one or more environment parameters when it is recognized that the monitoring result of the monitoring component on the one or more vital sign parameters meets a first early warning condition.

The animal disinfection device comprises a base, a disinfection chamber is fixedly arranged at the top of the base, cleaning mechanisms are arranged at the two ends of the exterior of the disinfection chamber, U-shaped frames are movably connected to the inner walls of the two sides of the disinfection chamber, and displacement mechanisms used for moving the U-shaped frames are arranged on the inner walls of the two sides of the disinfection chamber. A spraying pipe is rotationally connected into the U-shaped frame, a plurality of spraying heads are evenly and fixedly arranged on the spraying pipe, a swing mechanism used for enabling the spraying pipe to swing left and right is arranged on one side of the U-shaped frame, the swing mechanism acts along with movement of the U-shaped frame, and a disinfectant box is fixedly arranged at the top of the disinfection chamber. And a liquid pumping assembly for conveying liquid to the spraying pipe is arranged at the top of the disinfection chamber. According to the animal disinfection device, dirt attached to the body surface of an animal can be cleaned, pathogens on the skin and the roots of hair can be exposed, a medicament can more comprehensively permeate the hair and cover the surface of the skin through swinging of the spray head, and the disinfection effect is effectively improved.

The utility model discloses a movable yak epidemic prevention and isolation protection device, and particularly relates to the technical field of epidemic prevention and isolation, the movable yak epidemic prevention and isolation protection device comprises a supporting plate, moving wheels are installed at the bottom end of the supporting plate, supporting assemblies are installed at the four corners of the supporting plate, fixing assemblies are installed on the supporting assemblies, climbing plates are hinged to the two ends of the supporting plate, and the climbing plates are hinged to the bottom end of the supporting plate. A transverse rod is connected between the fixing assemblies on the two sides of each climbing plate, and a plurality of handrails are installed between the fixing assemblies on the two sides of the supporting plate. The yaks can enter by opening the climbing plate, the rails are used for limiting the yaks to move so as to facilitate epidemic prevention injection, and the climbing plate can be closed to transfer the yaks; the supporting assembly and the fixing assembly are matched to adjust the protection height. The method is easy and convenient to operate and high in practicability, and the efficiency and safety of yak epidemic prevention work are effectively improved.

This invention belongs to the field of animal model construction technology, specifically relating to a mouse immunosuppressive model that maintains a long-term immunosuppressive state, its construction method, and its application. This invention establishes a stable immunosuppressive state model with reduced neutrophil count and no significant decrease in erythrocyte count by administering different doses of immunosuppressants (10-50 mg / kg body weight) to Balb / c mice via a combination of "reduced total dose + multiple gavage administration + satellite monitoring." The method for constructing this mouse immunosuppressive model reduces drug usage, controls neutrophil count rebound, establishes a stable model of reduced neutrophil count, and avoids deep bone marrow suppression (i.e., does not cause an uncontrollable decrease in erythrocyte or platelet count), which is beneficial for long-term experimental conduct and drug evaluation.

The invention relates to a capsule type oxygen cabin for animal experiments, which adopts a modular structure, comprehensively considers the influence of multiple factors such as temperature, humidity, pressure and oxygen concentration, and also considers the influence of breathing oxygen consumption of experimental animals and the influence of a first / second accommodating part, and on the basis, the first / second accommodating part is centrally controlled through a touch screen; according to the method, the combination of multiple modes can be realized, so that the climate conditions of different regions can be accurately, efficiently and stably simulated, and accurate and scientific guidance can be provided for the research on'high reflection ', the work and life of personnel in high and cold climate regions and the pathology research of hospitals. Besides, the electrical parts are classified and placed in the first accommodating part, the second accommodating part, the touch screen and the bearing part, so that the cabin body can be transparent and visual, and the electrical parts in the first accommodating part and the second accommodating part are convenient to overhaul through detachable connection between the first partition plate and the second partition plate and the first accommodating part and between the first partition plate and the second partition plate and the second accommodating part.

Various examples describe a livestock monitoring system and method. A sensor signal may comprise a rotational component describing a rotation of the sensor within an animal and a linear component describing a linear movement of the sensor within the animal. The rotational component may be used to identify an animal respiration signal. The animal respiration signal and the linear component may be used to generate a respiration-corrected linear component. An animal heart signal may be detected from the respiration-corrected linear component.

The invention discloses a pressure-adjustable needleless injector based on double springs, and belongs to the technical field of needleless injectors.The technical scheme is that the pressure-adjustable needleless injector comprises an injection head shell, an injection cavity is formed in the injection head shell, and an open hole communicating the outside with the injection cavity is formed in the front end of the injection head shell; an injection push rod extending into the injection cavity is arranged at the rear end of the injection head shell; a transmission assembly is arranged between the driving mechanism and the injection push rod, the transmission assembly comprises a first barrel and a second barrel which are parallel to each other, transmission push rods are arranged in the first barrel and the second barrel in a sliding mode, the two transmission push rods are sleeved with percussion springs, and the two percussion springs are consistent in parameter but different in initial compression amount; the switching connection between the two transmission push rods and the injection push rod is realized by the two transmission push rods through a detachable switching piece; switching connection between the two transmission push rods and the driving mechanism is achieved through detachable connecting pieces. The pressure-adjustable needleless injector has the beneficial effect that the pressure-adjustable needleless injector based on the double springs is provided.

[Problem] To provide a wheelchair which is for a four-legged animal and which is less likely to fall over by moderating the inclination of a disabled limb-side holder due to a state change of a road surface or the body, has a sense of security, has high safety, and allows stress-free walking based on free will. [Solution] The present invention comprises: a disabled limb-side holder 3; at least one pair of left and right wheel arms 5 that are provided at left and right positions of the disabled limb-side holder 3 and pivotally support wheels 6; and a wheel lifting / lowering mechanism 7 that independently changes the relative heights of the wheels 6 with respect to the disabled limb-side holder 3 so as to moderate the inclination when the mounted disabled limb-side holder 3 is inclined due to a state change of the road surface or the body.

The invention discloses an experimental animal intracerebral target accurate injection system and method based on artificial intelligence and ultrasonic guidance, and relates to the technical field of target injection, the system comprises an ultrasonic probe for emitting ultrasonic waves, receiving experimental animal craniocerebral echo signals and outputting radio frequency signal data; the image processing module is used for executing time gain compensation and beam forming on the radio frequency signal data and outputting gray scale image data and blood flow image data; the artificial intelligence reasoning module is used for inputting the gray-scale image data and the blood flow image data into a convolutional neural network model and outputting corresponding coordinates; the path planning unit is used for generating an entry point coordinate, an angle parameter and a depth parameter through an optimization algorithm; the puncture guide frame adjusts the spatial position of the puncture needle according to the angle parameter and the depth parameter; and the needle point tracking unit is used for calculating a deviation value between the needle point coordinate and a preset track and generating an early warning signal. The problem of inaccurate positioning caused by individual difference in a traditional method is fundamentally solved.

Animal ear tag (1) for marking farm animals, in particular cattle, pigs, goats and sheep, with the following characteristics: - the animal ear tag (1) comprises a plastic material; - an antimicrobial additive is incorporated into the plastic; - the animal ear tag (1) comprises a first tag part (2) and a second tag part (3) which are designed to be attached to each other and to an ear (4) of the farm animal; - the first trademark part (2) comprises the plastic into which the antimicrobial additive is incorporated and the second trademark part (3) comprises the plastic into which the antimicrobial additive is incorporated; - the first mark part (2) comprises a mark body (5) and a pin (6) which is arranged at its first end (6a) on the mark body (5) and which comprises a point (7) and / or cutting edge at its second end (6b); - the second mark part (3) comprises a mark body (8) and a receiving element (9) which is arranged on the mark body (8); - the pin (6) of the first tag part (2) is designed to be pushed through an ear (4) of the farm animal and into the receiving element (9) of the second tag part (3); - the identifier body (5) of the first trademark part (2) comprises the plastic into which the antimicrobial additive is incorporated; and - the identifier body (8) of the second trademark part (3) comprises the plastic into which the antimicrobial additive is incorporated; - the antimicrobial additive is evenly distributed throughout the plastic; - the antimicrobial additive includes a silver component.

A device for applying fluid is provided, comprising: a cylinder (13); a piston (26) movable within the cylinder (13) between a front end position and a rear end position and connected to a piston rod (25); and a tensioning device (S) connected to the piston rod (25); wherein the tensioning device (S) has a ramp (42) rotatable by a motor (51) and a ramp path (41) extending along a helical line; wherein the tensioning device (S) further comprises a roller (40) contacting the ramp path (41) and rotatably mounted in a driver (31) connected to the piston rod (25), such that when the ramp (42) rotates in a first rotation direction (52), the ramp path (41) travels below the rotating roller (40); wherein a dose setting device (36) is provided, comprising a spacer (70) and a moving unit, wherein when the moving unit... When the plug (26) is in its rear end position, the moving unit can move the spacer (70) from the neutral position where the spacer (70) is not located between the driver (31) and the cylinder (13) into the working position between the driver (31) and the cylinder (13), such that the driver (31) is stopped by the spacer (70) after the roller (40) passes through the transition area (46), thereby resulting in a shorter piston stroke during the movement of the piston (26) toward the open distribution end compared to when the spacer (70) is in its neutral position; wherein the spacer (70) has a through hole (140) in which a spindle (143) having a spindle thread (142) is guided, wherein the spacer (70) has a pin (141) protruding into the spindle thread (142), and wherein the spindle thread (142) is inserted into an annular groove (144, 145) at at least one of its two ends.

The invention discloses an assembled smoke inhalation injury experiment device, and relates to the technical field of medical experiment equipment. Comprising a combustion tank main body, a fixed base is arranged at the lower end of the combustion tank main body, an air guide cover is arranged at the upper end of the combustion tank main body, smoke guide pipes are evenly arranged on the two sides of the air guide cover, anti-leakage structures are arranged in the smoke guide pipes, and mounting bases are arranged on the two sides of the combustion tank main body; a connecting structure is arranged between the experiment box and the combustion tank body, the combustion tank body and the experiment box are made of transparent materials, so that experimenters can clearly observe internal combustion and smoke flowing conditions, experiment data can be conveniently monitored and recorded in real time, fuel can be stably combusted through the design of the combustion base, and the combustion efficiency is improved. The igniter provides a convenient ignition mode, it is ensured that the experiment can be started rapidly, the oxygen content in the combustion tank can be adjusted through the arrangement of the oxygen inlet pipe, and therefore combustion conditions in different environments can be simulated.

The utility model discloses a chick spraying immunization device which comprises a base, an immunization box with the top provided with a spraying mechanism and a chick frame with the bottom provided with a protruding block, a first lifting mechanism for driving the immunization box to ascend and descend is installed on the base, a feeding port is formed in one side of the immunization box, and a platform and a second lifting mechanism for driving the platform to ascend and descend are arranged outside the feeding port. The upper end face of the platform and the bottom end of the feeding port are flush with the bottom end of the immune box, and a roller conveyor and a fixing plate are sequentially arranged in the immune box from top to bottom; the fixing plate is provided with limiting blocks for placing the protruding blocks, the bottoms of the two sides are connected with rollers, the middle of the fixing plate is provided with a through groove for the roller conveyor to vertically penetrate through, the immunization box is provided with a third lifting mechanism for driving the roller conveyor to ascend and descend and a translation mechanism for driving the fixing plate to directionally slide towards the platform, and the side, away from the feeding port, of the fixing plate is connected with a cleaning assembly. The functions of adjusting the height of the immunization box and automatically cleaning the roller conveyor are achieved, and the whole feeding device has the advantages of being high in feeding precision, convenient to clean and low in labor intensity.

Systems and methods for treating and / or preventing metabolic disorders and / or other medical conditions in patients (e.g., felines) are described, by administering a liquid pharmaceutical composition, preferably containing one or more SGLT-2 inhibitor compounds, to the patient via a delivery system including a syringe. The syringe is characterized by facilitating the simple, safe, and effective dosage of small volume measurements of the liquid pharmaceutical composition to the patient during administration.