1126results about "Veterinary instruments" patented technology

A bioenergy generator to increase the life force of a biological system is provided. The bioenergy generator includes fine pieces of natural stone, fine pieces of natural sand, fine pieces of metal, water and a supporting material operable to hold the natural sand, the natural stone, the metal, and the water together. Uses of the bioenergy generator are also provided, in particular, to enhance stem cell production.

A system suitable for collecting and transporting urine away from the body of a person or animal may include an assembly having a fluid impermeable casing having a fluid reservoir at a first end, a fluid outlet at a second end, and a longitudinally extending fluid impermeable layer coupled to the fluid reservoir and the fluid outlet and defining a longitudinally elongated opening between the reservoir and the outlet. The assembly can further include a fluid permeable support disposed within the casing with a portion extending across the elongated opening, and a fluid permeable membrane disposed on the support and covering at least the portion of the support that extends across the elongated opening, so that the membrane is supported on the support and disposed across the elongated opening. The assembly can further include a tube having a first end disposed in the reservoir and a second, fluid discharge end.

A microminiature insect smell induction and smell selection behavior observation device is characterized in that a smell induction device comprises a feeding chamber (1) and connecting pipes connected to the two ends of the feeding chamber (1), and the outer sides of the connecting pipes are connected with a smell storage chamber; air holes (15) are formed in the top of the feeding room (1), and a solution delivery device is arranged on the front; each connecting pipe is composed of a high-density sponge hollow sealing plug and a plastic sleeve with one end open and the other end provided with a breathable gauze element. The smell storage chamber is composed of a smell storage chamber body and a closed silica gel plug or a hollow silica gel plug, the two ends of the smell storage chamber body are open, and a breathable gauze is arranged in the center in the smell storage chamber body to prevent the trichogramma ovipositor from touching smell substances. The device is simple in structure, is suitable for smell research of trichogramma, has the advantages of high efficiency and labor saving, and can obviously improve the experiment efficiency.

Systems and methods for detecting lameness in a limb of an animal using a machine learning model are described herein. In an implementation, a system receives first data measurements from a sensor device attached to the animal, where the first data measurements represent measurements associated with gait of an animal. Start and stop times are determined for movement events identified from the first data and the movement events are stored. A first machine learning model is used to generate levels of gait asymmetry using the movement events as input. The first machine learning model is a model trained to predicts levels of gait asymmetry based on movement data. Upon generating the levels of gait asymmetry, one or more treatment recommendations are generated based on the levels of gait asymmetry. The one or more treatment recommendations and levels of gait asymmetry are displayed on a client computing device.

The invention discloses a mouse spinal cord flexible electrode and a stimulation parameter optimization method, and relates to the technical field of parameter optimization. The mouse spinal cord flexible electrode comprises a soluble insertion layer, a gradient substrate layer, spinal cord anastomosis ribs, a conductive snakelike net, a hemispherical touch dot matrix, a microfluidic layer, an optical waveguide layer and a top packaging layer; the soluble insertion layer is photo-crosslinked PEG-DMA with the thickness of 5-25 m, the Young modulus is kept within the range of 0.8-1.5 GPa before implantation, and the soluble insertion layer is hydrolyzed in cerebrospinal fluid within 0.5-3 hours after implantation and completely falls off; the spinal cord anastomosis rib comprises an expandable S-shaped folding structure arranged on the upper surface of the gradient substrate layer, the distance between every two adjacent ribs ranges from 80 m to 200 m, the height of the folded state is not larger than 15 m, the height of the unfolded state ranges from 15 m to 40 m, and the spinal cord anastomosis rib is used for forming a cerebro-spinalfluid bypass groove extending in the longitudinal direction of the spinal cord on the surface of the dura mater. According to the invention, the positioning precision, safety and long-term efficiency of mouse spinal cord electrical stimulation can be effectively improved.

The invention belongs to the technical field of biotechnology and animal models, and discloses a double-person-derived mouse model for simulating a tumor immune microenvironment and a construction method and application thereof. The method comprises the following steps: firstly, pretreating NSG immunodeficient mice by adopting low-dose whole-body irradiation in combination with double-antibody targeted bone marrow depletion, and transplanting CD34 + hematopoietic stem cells from the same human donor to complete human immune system reconstruction; separating tumor primary cells, tumor-related fibroblasts and tumor vascular endothelial cells of the same donor, performing three-dimensional co-culture to obtain homologous human tumor organs, and performing in-situ inoculation to immune reconstruction mice to obtain a target model. The core defects of MHC mismatching, low immune reconstruction efficiency, poor tumor immune microenvironment simulation degree, low clinical consistency and the like of an existing model are overcome, and the method can be used for tumor immune treatment drug screening, microenvironment mechanism research and personalized tumor treatment scheme verification.

The invention discloses a humanized osteoporosis mouse model and a construction method thereof, and belongs to the technical field of biotechnology and animal models. The invention aims at the core defects of large species difference, insufficient humanization degree, low pathological simulation degree, unstable phenotype and the like of the existing osteoporosis model. The humanized osteoporosis mouse model is constructed through five core steps of experimental animal pretreatment, collagen-nano hydroxyapatite bionic scaffold preparation and cell pre-implantation, immune-bone metabolism double-derived system construction, progressive osteoporosis induction and model identification and verification. According to the method, double-person origination of immune and bone metabolism systems is realized for the first time, the colonization rate and survival time of human cells are greatly improved, the pathological process of clinical postmenopausal osteoporosis is accurately simulated, the phenotype of the model is stable and uniform, the reactivity matching degree with clinical drugs is high, and the method can be widely applied to research and development of anti-osteoporosis drugs and research of pathological mechanisms.

The invention discloses wearable pet multifunctional physical therapy health equipment and a use method thereof. The wearable pet multifunctional physical therapy health equipment comprises a biocompatible flexible substrate and wearing system, an intelligent moxibustion warm physical therapy module, a multifunctional phototherapy module, a bionic micro-vibration massage module, a vital sign real-time monitoring system, an intelligent control and energy system and an omnibearing safety protection system. A biocompatible flexible substrate and a wearable system are adopted as carriers, multiple modules such as intelligent moxibustion warm physical therapy, multifunctional phototherapy, bionic micro-vibration massage and vital sign real-time monitoring are integrated, cooperative operation is achieved through intelligent control and an energy system, and meanwhile an all-around safety protection system runs through all the time. The integrated design breaks through the limitation that traditional pet physiotherapy equipment is single in function. The device has the core advantages that the accuracy of cross-species treatment is improved, the concealment of the treatment process is guaranteed, and human-pet-medical collaborative management is realized.

The invention discloses a laboratory mouse temporomandibular joint cavity injection method and device based on ultrasonic guidance, and relates to the technical field of laboratory mouse experiments.The device comprises a supporting column, a first cantilever arranged on the supporting column, an external auditory canal positioning piece arranged on the first cantilever, and a second cantilever arranged on the first cantilever in a sliding mode, the second cantilever can rotate around the end, close to the first cantilever, of the second cantilever, and the second cantilever is used for being parallel to the orbital ear plane of the laboratory mouse; the carrying mechanism is arranged on the second cantilever in a sliding mode, and the carrying mechanism is used for driving the ultrasonic probe and the injector to move to the position of the articular cavity. Injection of the joint cavity of the laboratory mouse is guided based on the image collected by the ultrasonic probe, the needle inserting position, angle and depth of the injector can be observed and adjusted in real time, and compared with blind puncture in the prior art, the success rate of injection can be greatly increased, the number of times of puncture attempts can be reduced, and meanwhile the uniformity of laboratory mouse samples is effectively improved.

To provide an oxygen concentration adjusting device capable of performing proper oxygen therapy by adjusting the oxygen concentration of oxygen gas from an oxygen source fed into a cage, rather than adjusting the oxygen concentration by a gap opened in the cage. [Solution] An oxygen concentration adjusting device 12 supplies oxygen gas, adjusting the oxygen concentration of the oxygen gas to supply oxygen gas with an optimum oxygen concentration. Here, the oxygen concentration of the oxygen gas is controlled by a needle valve 12A that can vary the oxygen flow rate of the oxygen gas, and the oxygen gas is supplied to a cage 14 housing a small animal A or to an anesthesia machine.

The invention discloses a drug screening method based on endotoxin attack, and relates to the technical field of drug screening, in the process of drug screening by using an experimental animal, firstly, an experimental animal model with diseases is established, a certain dose of endotoxin is given to the experimental animal for a period of time after the model is successfully built, and then the experimental animal is subjected to drug screening. And establishing evaluation indexes by utilizing a mathematical formula, and comprehensively evaluating the effectiveness and the safety of the medicine. The evaluation indexes comprise an endotoxin attack survival rate, a survival disease control rate and a survival disease control index. The method can be applied to screening of drugs for treating different diseases, and a more scientific and reliable screening method is provided for research of preclinical drugs or treatment methods.

The invention provides a computer simulation method and device for determining the position of an electrode patch. The method comprises the following steps: acquiring a mouse simulation model, wherein the mouse simulation model is obtained by performing three-dimensional reconstruction on a mouse with a brain tumor; simulation electrode patch pairs are sequentially arranged at multiple pairs of candidate positions in the head area of the mouse simulation model, and simulation alternating electric signals are applied to the simulation electrode patch pairs; for each pair of candidate positions in the multiple pairs of candidate positions, recording an electric field intensity value of a simulation electric field established between the simulation electrode patch pairs by the simulation alternating electric signals when the simulation electrode patch pairs are arranged at the candidate positions; selecting a pair of candidate positions with the maximum electric field intensity value from the plurality of pairs of candidate positions as target electrode patch positions; and determining an electrode patch corresponding to the position of the target electrode patch according to the position of the target electrode patch.

The invention relates to the technical field of medical instruments, in particular to an electromagnetic needleless injector which comprises a shell, a nozzle assembly, a liquid storage assembly, a driving assembly and an intelligent control system. Firstly, a series excitation linear motor is adopted to replace a traditional needleless injector driven by a spring, and the problems that driving force is limited and elasticity is attenuated due to the spring are effectively solved. According to the series excitation linear motor, through excitation magnetic field coupling between the stator coil and the rotor coil in the motor, the rotor directly drives the plunger rod to do linear motion in the axial direction so as to complete injection, the structure is simpler, the direct drive type connection structure is adopted, the stability is higher, and force transmission is more accurate. In addition, an intelligent control system integrated in the needleless injector enables the needleless injector to be more intelligent, control precision is higher, operation is more convenient, the needleless injector can be wirelessly connected with a breeding cloud management system, rapid, accurate and painless injection of live pigs and other animals can be achieved, and breeding efficiency and injection safety are improved.

The invention discloses a preeclampsia mouse model. The preeclampsia mouse model is constructed by the following method: (1) combining a female mouse with a male mouse; (2) in the middle stage of pregnancy, intragastric administration of hypoxanthine and oteracil potassium salt is carried out on the pregnant mouse for a period of time; the invention also discloses a construction method and application of the gene. The invention provides a novel preeclampsia modeling mode, hypoxanthine and oteracil potassium salt are combined for use, and the administration dosage and the administration mode of hypoxanthine and oteracil potassium salt are controlled, so that the serum uric acid level of a model mouse is stably increased, preeclampsia change occurs in the model mouse, and the model mouse can be used for treating preeclampsia. The stability, specificity and pathophysiology characteristics of the model are ensured to be similar to those of human preeclampsia, so that the uric acid-induced preeclampsia mouse model is successfully constructed. The uric acid induced preeclampsia mouse model provides a valuable tool for researching the pathogenesis of preeclampsia, evaluating a new treatment method and understanding the effect of serum hyperuricemia in preeclampsia.

A variable sensor system for non-contact vital sign monitoring of animals is described. Non-contact vital sign monitoring may involve correcting measured signals for reflectance and variations in distance between measurements. Non-contact vital sign detection may include temperature detection, and / or measuring cardiovascular and respiratory information. Embodiments are described using a non-contact variable sensor integrated with a weight scale, integrated with a drone, having a pan-tilt monitoring feature, integrated with a kennel, integrated with an automatic pass-fail interface, and including a medication dispensing control module.

The invention relates to the technical field of veterinary epidemic disease detection, and discloses a veterinary epidemic disease remote monitoring and intelligent diagnosis system, which comprises a multi-mode biosensor array including an implantable miniature biochip, a wearable flexible physiological monitoring patch and an environment sensing sensor cluster, the implantable miniature biochip is used for being implanted into a key tissue organ area in an animal body and collecting microscopic physiological data such as cellular metabolism signals and local immune reaction marker concentration in real time, and the wearable flexible physiological monitoring patch is used for being attached to the body surface of the animal. By means of the multi-mode biosensor array and the edge intelligent preprocessing unit, animal physiology and environment data are accurately monitored in real time. The multi-modal biosensor array covers the implantable miniature biochip, the wearable flexible physiological monitoring patch and the environment sensing sensor cluster, and can comprehensively collect in-vivo microscopic physiological data, body surface macroscopic physiological parameters and feeding environment information of animals.

A delivery device suitable for delivering a chemical substance, e.g. a medical device such as a catheter, a microcapsule, an implantable capsule or a P-ring, or a delivery device for use in the construction industries e.g. in the form of microcapsules comprising antifouling agent for marine paint. The delivery device includes a closed cavity, the cavity is defined by an innermost wall surface, wherein at least a section of the inner wall surface constitutes an inner surface of a delivery membrane wherein the delivery membrane includes an interpenetrating polymer network substrate comprising a host polymer and a guest polymer, where the guest polymer is interpenetrating the host polymer to form substantially continuous pathways within said host polymer.

The invention discloses a construction method and application of a preeclampsia animal model based on an RASA3 target, and belongs to the technical field of biomedicine.The preeclampsia animal model is constructed by injecting Ad-RASA3 into a pregnant mouse and monitoring pathological indexes, related to preeclampsia, of the pregnant mouse. According to the method, the animal model with preeclampsia-like clinical symptoms can be stably induced, the abnormal change of the uterine spiral artery remodeling process can be systematically monitored, the method is high in operation controllability and model stability, and an effective tool can be provided for deeply researching the pathogenesis of preeclampsia and developing a novel diagnosis and treatment strategy.

The invention relates to the technical field of biology, in particular to a construction method of an obstructive sleep apnea animal model. The invention provides a construction method of an OSA animal model, which comprises the following steps: respectively injecting 50% glycerol or LPS (lipopolysaccharide) on both sides of the palatopharyngeal muscle of a rabbit to construct the OSA animal model. The method not only can simulate the OSA comprehensively from dissection and pathophysiological features, but also has the advantages of high safety, high success rate and no need of high-end equipment and special operation. The method accords with a clinical practical OSA animal model, has a great promotion effect on revealing OSA pathogenesis, developing new drugs and the like, and has a good application prospect.

The invention is a smart crate that includes a variety of improved features to promote safety and peace for both the pet and owner. Specifically, the disclosed crate includes smart technology with a remote monitoring system that allows a user to view, hear, and / or communicate with an animal positioned within the crate. Accordingly, pet and owner anxiety is thereby reduced or eliminated. The crate also includes improved safety features, such as an automatic locking element that allows a user to remotely open and close the crate door. In this way, the animal is allowed to exit the crate interior, such as in the case of an emergency.

The invention discloses a construction and evaluation method of a PM2.5 induced chronic obstructive pulmonary disease acute exacerbation mouse model, and relates to the technical field of disease animal models. The invention aims to evaluate whether PM2.5 can induce acute exacerbation of COPD through a mouse model, a COPD model is established by adopting combined treatment of smoking and lipopolysaccharide (LPS), and an infectious AECOPD model is established by using common klebsiella pneumoniae (KP) nasal drop on the basis. Meanwhile, PM2.5 processing is added on the basis of the COPD model, and the effect of PM2.5 on acute exacerbation of COPD is evaluated. Through comparison with a classical model (an infectious AECOPD model), the potential effect of PM2.5 in induction of acute exacerbation of COPD is evaluated, and an important reference is provided for future research on an AECOPD animal model induced by air pollution.

The invention belongs to the technical field of molecular biology, and particularly relates to a construction method and application of a streptococcus pneumoniae pneumonia animal model. The invention provides a construction method of a streptococcus pneumoniae infected rat pneumonia and kidney injury model. The method comprises the following steps: S1, applying a streptococcus pneumoniae liquid into the respiratory tract of a rat by adopting an atomization bacterium feeding mode; and S2, verifying whether the rat treated in the step S1 is infected with pneumonia or not and whether kidney injury exists or not. According to the method, whether pneumonia is infected or not is judged by detecting inflammatory factors in alveolar lavage and lung HE staining, and whether kidney injury exists or not is judged by detecting the urine protein / creatinine ratio in a rat urine sample and detecting kidney HE staining. The construction method provided by the invention is convenient to operate, accurate in model construction and high in survival rate.

A semi-automated veterinary medicine delivery device may sense whether and how much air may have been incorporated into a dose delivered to an animal. The device may also sense an incomplete injection in some cases and may cause a second dose to be administered to make up for the incomplete dose. The device may compare a position sensor on a syringe in combination with a current sensor on a motor attached to the syringe to detect any abnormalities. In the case of an improper dose, the device may alert the user and administer a second dose.

The utility model relates to the technical field of livestock injectors, in particular to a poultry and livestock vaccine continuous injector which comprises a needle head, an injection tube and an adjusting assembly, and the adjusting assembly comprises a threaded tube, a threaded ring, a connecting rod, a supporting plate, a piston rod, a puncture tube and a medicine bottle. The injection tube is used for storing medicine needing to be injected, the medicine bottle contains the medicine needing to be injected and is added into the injection tube through the puncture tube, one end, away from the injection tube, of the puncture tube is designed to be sharp, so that the medicine can be conveniently punctured into the medicine bottle, and the piston rod is pushed in the injection tube to push out the medicine; the length of the needle head extending out of the supporting plate is controlled by rotating the position of the threaded ring on the outer side of the threaded pipe, the supporting plate makes contact with the epidermis of the poultry and livestock in the injection process, and therefore the position extending out of the supporting plate can puncture the body of the poultry and livestock.

A device for dispensing a fluid drop-by-drop can include a fluid connector to supply the fluid to be dispensed, a pump which is fluidically connected to the fluid connector, an outlet nozzle which is fluidically connected to the pump, an actuating element, and a control unit. When the actuating element is actuated, the control unit activates the pump which pumps the supplied fluid to the outlet nozzle for dispensing drop-by-drop. The outlet nozzle has an outlet opening and a fluid channel which extends as far as the outlet opening and which, in the direction of the fluid from the pump as far as the outlet opening, has a first channel portion with a first cross-sectional surface and a second channel portion with a second cross-sectional surface adjoining the first channel portion. The second cross-sectional surface can be smaller than the first cross-sectional surface.

The utility model discloses a disinfection spraying device for animal husbandry veterinarians, which belongs to the technical field of animal husbandry disinfection and comprises a disinfection aisle, an inner cooling arc shell is arranged on the inner side of the disinfection aisle, door curtains for shielding are arranged at channel openings on two sides of the disinfection aisle, and the disinfection aisle is arranged above the ground of an installation position. The device comprises a disinfection aisle, a disinfectant box is arranged below the disinfection aisle, at least one spraying plate is arranged on the inner side of the disinfection aisle, the spraying plate is designed to be hollow, a plurality of nozzles are installed on one side of the spraying plate, a filter plate is embedded and clamped in the disinfectant box, a pressure sensitive switch is arranged at the top of the filter plate, and a bearing plate is arranged at the inner bottom of the disinfection aisle. Pressing columns are fixed to the positions, corresponding to the pressure-sensitive switches, of the bottom of the bearing plate. The disinfection spraying device for animal husbandry and veterinary medicine can be automatically started, automatic disinfection of animal husbandry is achieved, manpower is reduced, meanwhile, convenience is greatly improved, and disinfectant can be recycled.

The embodiment of the invention discloses a method and system for emission computed tomography for animal imaging. The method comprises the steps that a plurality of imaging animals are placed on a plurality of trays in preset placement postures, each tray is configured to place one imaging animal, each tray comprises a body part fixing part, and the body part fixing parts are configured to fix the preset placement postures of the imaging animals placed on the body part fixing parts; placing a plurality of trays on the supporting part of the multi-imaging animal fixing device; the multi-imaging-animal fixing device is placed in an animal cabin of scanning equipment, and emission computed tomography is carried out on multiple imaging animals at the same time.

The invention relates to the technical field of medical instruments, in particular to a veterinary venous indwelling needle fixing and protecting system and an anti-falling application method.The veterinary venous indwelling needle fixing and protecting system comprises a first neck sleeve, a second neck sleeve and a flexible sleeve fixedly connected between the first neck sleeve and the second neck sleeve, a gap is formed in the top end of the flexible sleeve, and a notch is formed in the inner end, close to the gap, of the flexible sleeve; a notch is formed in the outer wall of the flexible sleeve, an indwelling groove is formed in the position, close to the notch, of the outer wall of the flexible sleeve in a penetrating mode, a connecting belt is fixedly connected to the position, close to the indwelling groove, of the outer wall of the flexible sleeve, a pawl is fixedly connected to an inner belt of the connecting belt, a hook-and-loop fastener belt is fixedly connected to one end of the connecting belt, and fifth hook-and-loop fasteners distributed on the flexible sleeve adhere to the hook-and-loop fastener belt; according to the pet indwelling needle, the pawls of the connecting belt are meshed with the pawl grooves, secondary reinforcement is achieved in cooperation with the hook-and-loop fastener belt, and the breathable film sticker is matched for limiting, so that the indwelling needle is effectively prevented from shifting and falling off due to movement of a pet.

The utility model relates to the technical field of veterinary medicine feeding, and discloses an anti-bite animal husbandry veterinary medicine feeding device which comprises a bite assembly, the bite assembly comprises a bite block, a bite elastic column is arranged in the bite block, and an extending pipe is arranged in the bite block in a penetrating mode. The needle tube assembly comprises a needle tube body, a piston rod cover piece used for pushing liquid medicine is arranged on the needle tube body, one end, close to the piston rod cover piece, of the needle tube body is fixedly connected with a clamping plate, and one end, far away from the piston rod cover piece, of the needle tube body is in threaded connection with an installation nut. According to the utility model, through the arrangement of the occlusion assembly, the occlusion block can be placed in the mouth of an animal to be bitten by the animal, so that the needle tube body is prevented from being bitten and damaged, and medicine feeding can be carried out smoothly; through the arrangement of the needle tube assembly and the placing assembly, the piston rod can be automatically pushed, manual pushing of the piston rod is not needed, labor and time are saved in use, various kinds of liquid medicine can be contained, and use is convenient and practical.

This disclosure features tissue storage, irrigation, and infusion media compositions, and methods of using such compositions, for example, the temporary storage of cells and tissues prior to implantation or re-implantation, or for wound irrigation, wound packing, surgical site irrigation, or intravenous infusion. The tissue storage, irrigation, and infusion media compositions disclosed herein are useful in a healthcare or veterinary setting.