187 results about "Treated animal" patented technology

The present invention provides a preparation for animals, with which a medicine can be retained in an oral cavity of an animal for a sufficient time or a medicine can be released rapidly in an oral cavity of an animal.　The present invention relates to a film preparation capable of adhering to oral cavities of animals, the film preparation having at least one film layer containing a prophylactic or therapeutic medicine for an animal disease and an easily-water-soluble polymer.

The present disclosure relates to flavor compositions and pet food products for preventing and / or treating chronic kidney disease (CKD) and / or urinary tract disease in an animal. In certain embodiments, the flavor compositions and pet food products have enhanced palatability.

The claimed group of inventions relates to a field of veterinary medicine and concerns a water-soluble supramolecular complex with afoxolaner, a method for production thereof, and veterinary drugs comprising said complex as a main active component to prevent or to treat parasite infections in animals. The inventive complex is a fine powder having a particle size of less than 1 micron that is an inclusion of afoxolaner molecules into the structure of 2-hydroxypropyl-β-cyclodextrin, stabilized by polysorbate 80 and may be used in veterinary drugs having antiparasite effect for effective oral and parenteral administration.

Provided in the present application are an isoxazoline compound as shown in formula (I), a pharmaceutical composition thereof, and the use thereof in the prevention or treatment of infestation or infection by animal parasites. The compound has excellent insecticidal and acaricidal activities against internal or external parasites of mammals, poultry or fishes.

The present invention relates to the technical field of veterinary medicinal products and specifically to a composition for the treatment of a skin disease in an animal. The main active ingredients of the composition are rapamycin, miconazole, and meloxicam in a mass ratio of (0.01–10):(0.1–20):(0.1–5) and a solvent mixture of water and polyethylene glycol in which the main active ingredients are soluble. The composition has considerable curative effects on fungal infections on the skin surfaces of animals, with low toxicity and minimal irritation.

The present invention relates to a pharmaceutical composition for topical use comprising a corticosteroid and an insecticide selected from pyrethrins or synthetic pyrethroid-based insecticides. Also described are methods of using the compositions of the invention for the treatment of allergic dermatitis, in particular insect bite hypersensitivity, in an animal.

The invention relates to a veterinary hoof disease prevention and treatment composition as well as a preparation method and application thereof, and aims to solve the technical problems that existing commercial hoof bath lotion is limited in sterilization effect and relatively strong in local irritation, and a safe and efficient treatment medicament for treating cow hoof warts is lacked and the like. The invention provides a veterinary composition which comprises the following active ingredients: a glycyrrhizic acid compound, didecyl methyl ammonium bromide and polyhexamethylene guanidine salt, and the three components are combined, so that the composition has an antibacterial effect and an effect of promoting skin tissue repair at the same time. A series of tests prove that the traditional Chinese medicine composition can effectively inhibit animal pathogenic bacteria, prevent and / or treat animal limb and foot diseases and promote healing and repairing of ulcer injury. The medicament disclosed by the invention is suitable for preventing and treating limb and hoof diseases in a large-scale pasture, has the characteristics of high sterilization efficiency, good safety and effective treatment, and can improve the animal hoof health management level.

A fusion polypeptide comprising an extracellular domain of human CTLA-4 and an extracellular domain of human PD-L1 and an immune composition comprising such for use in treating cancer in animals such as dogs and cats.

The present disclosure provides, inter alia, pharmaceutical compositions for and methods of treating an animal, including a human, and methods of preparing such compositions. In certain embodiments, the pharmaceutical compositions contain nonabsorbable pharmaceutical composition and may be used, for example, to treat eubicarbonatemic metabolic acidosis.

To provide amphiphilic gemcitabine prodrugs or amphiphilic prodrugs of other biologically active molecules with the capacity to make liquid crystalline nanostructured nanoparticles, and uses thereof to treat animals, including humans.SOLUTION: The invention provides compounds such as 2'-deoxy-2',2'-difluoro-N4-(((cis-9, octadecenyl)oxy)carbonyl) cytidine (Gem-oleyl).SELECTED DRAWING: None

The present invention relates to the technical field of veterinary drugs, and more particularly, to a composition for treating a skin disease in an animal. The main active ingredients of the composition are rapamycin, miconazole, and meloxicam in a mass ratio of (0.01-10):(0.1-20):(0.1-5), and a mixed solvent containing water and glycerin in which the main active ingredients are soluble. The composition possesses significant curative effects on fungal infections on the skin surfaces of animals, with low toxicity and low irritation.

The present invention relates to platinum (IV) prodrug lipid-based amphiphiles and compositions thereof. In particular, it relates to cisplatin, oxaliplatin and carboplatin prodrugs with the capacity to make stable liquid crystalline nanoparticles and crystalline nanoparticles, and uses thereof to treat cancer in animals, including humans.

The present invention provides a method for preparing a MXene-based flexible force-sensitive nonwoven sensing fabric, comprising: preparing a MXene solution, including dissolving MXene in deionized water to prepare the MXene solution; pre-treating animal hair to remove impurities on the surface of the animal hair; repeatedly coating the pre-treated animal hair with MXene and drying it to form MXene-coated animal hair fibers; further treating the MXene-coated animal hair fibers to obtain a flexible force-sensitive nonwoven sensing fabric to be encapsulated; self-encapsulating the flexible force-sensitive nonwoven sensing fabric using a felting method to obtain animal hair felt; and evenly laying pure animal hair fibers on the animal hair felt for post-processing to obtain a MXene-based flexible force-sensitive nonwoven sensing fabric. Also provided is a force-sensitive fabric sensor, including a MXene-based flexible force-sensitive nonwoven sensing fabric prepared using the MXene-based flexible force-sensitive nonwoven sensing fabric preparation method; and a typical application of the force-sensitive fabric sensor in physiological signal monitoring.

Embodiments described relate to a medical device including an invasive probe that, when inserted into an animal (e.g., a human or non-human animal, including a human or non-human mammal), may aid in diagnosing and / or treating a lesion of the animal (e.g., a growth or deposit within vasculature that fully or partially blocks the vasculature). The invasive probe may have one or more sensors to sense characteristics of the lesion, including by detecting one or more characteristics of tissues and / or biological materials of the lesion. The medical device may be configured to analyze the characteristics of a lesion and, based on the analysis, provide treatment recommendations to a clinician. Such treatment recommendations may include a manner in which to treat a lesion, such as which treatment to use to treat a lesion and / or a manner in which to use a treatment device.

The present invention relates to a compound of formula (I) or a stereoisomer, or tautomer, (I) wherein A1, A2, R1 and R2, have the same meaning as that defined in the claims and the description. The present invention also relates to compositions, in particular pharmaceuticals, comprising such compounds, and to uses of such compounds and compositions for the prevention and / or treatment of an infection caused by pestivirus in an animal.

The invention describes novel serotonin c5-HT2B receptor antagonists of Formula (1), and pharmaceutically acceptable salts thereof; wherein Ring A, L, X, X′,R3, R4, m and n are as defined herein. Also described are compositions comprising a Formula (1) compound, or a pharmaceutically acceptable salt thereof; and methods of using the compounds, or a pharmaceutically acceptable salt thereof, for the treatment of myxomatous mitral valve disease (MMVD), congestive heart failure (CHF) and / or asymptomatic heart failure in animals, preferably is a canine.

The invention discloses Akkermansia muciniphila and application of a metabolite butyric acid of the Akkermansia muciniphila in preparation of drugs for relieving reproductive disorder of hypothalamus-pituitary-adrenal axis (HPA axis) and hypothalamus-pituitary-gonad axis (HPG axis), and develops a new function of the strain for relieving reproductive injury. The strain inhibits the HPA axis activity and reduces the stress hormone level by secreting butyric acid, so that the HPG axis function is activated, the reproductive system injury of ICR mice caused by high-density crowding stress is remarkably improved, and the sperm density is increased, the reproductive hormone level is increased, and the testis structure is improved. In addition, as a core metabolite of the Akkermansia muciniphila, the butyric acid can independently mediate the regulation and control process. The invention provides a new mechanism of animal population density-dependent reproductive homeostasis mediated by butyric acid, provides a potential micro-ecological intervention strategy for coping with reproductive capacity decline caused by social stress, and provides a new thought and method for treating animal and human reproductive injury.

The invention provides a hepatitis B virus receptor OATP and application thereof. Specifically, the invention provides an application of a substance in preparation of a medicament for preventing and / or treating animal hepatitis B virus (HBV) and / or hepatitis D virus (HDV) infection or diseases related to the infection, the substance prevents or reduces the interaction between HBV and / or HDV and an organic anion transporting polypeptide (OATP) in the animal and / or prevents or reduces the expression and / or function of OATP in the animal. The invention also provides an HBV and / or HDV susceptible cell model and animal model obtained by transferring an exogenous SLCO gene or expressing an exogenous OATP protein, an establishment method of the cell model and animal model, a drug delivery method and carrier for targeting OATP, and an OATP targeting delivery polypeptide carrier derived from a hepatophilic DNA virus surface antigen.

It is an object of the present invention to provide a composition for effectively preventing or treating Malassezia skin diseases.SOLUTION: The above problem can be solved by a composition for preventing or treating Malassezia dermatosis comprising citral of the present invention as an active ingredient, or a method for preventing or treating Malassezia dermatosis of an animal comprising a step of bringing an effective amount of citral into contact with the skin of an animal (excluding human).SELECTED DRAWING: None

The invention belongs to the field of biological pharmacy and animal medicine, and particularly relates to a nano antibody of antibacterial hair adhesin protein CfaE as well as a preparation method and application of the nano antibody. The invention provides a nano antibody mVHH-IgA of antibacterial hair adhesin protein CfaE, the nano antibody at least comprises a VHH fragment, the VHH fragment comprises three amino acid fragments of CDR1, CDR2 and CDR3, and the amino acid sequence of the CDR1-3 is shown as SEQ ID NO.1-3 in sequence, or the amino acid sequence of the CDR1-3 is shown as SEQ ID NO.4-6 in sequence, and the nano antibody mVHH-IgA of the antibacterial hair adhesin protein CfaE is prepared from the nano antibody mVHH-IgA of the antibacterial hair adhesin protein CfaE, the nano antibody mVHH-IgA of the antibacterial hair adhesin protein CfaE and the nano antibody mVHH-IgA of the antibacterial hair adhesin protein CfaE. Meanwhile, the VHH fragment is also fused with a secreting type IgA alpha chain constant region. The nano antibody mVHH-IgA provided by the invention has high specificity and stability, the nano antibody mVHH-IgA as a feed additive is mixed with a conventional feed to feed animals, and animal experiments show that the animal bacterial diarrhea can be effectively treated by feeding the feed containing the nano antibody mVHH-IgA provided by the invention.

The disclosure relates to compositions and methods of bacterial species expressing endolysins for the prophylaxis and treatment of methanogen growth in the digestive tract of an animal. More specifically, the disclosure relates to agents, compositions, and methods for preventing and / or inhibiting growth of methanogens.

The present invention relates to the field of animal health. In particular, the present invention relates to a recombinant classical swine fever virus comprising at least one substitution within the epitope of the E2 protein specifically recognized by the 6B8 monoclonal antibody. In addition, the present invention provides an immunogenic composition comprising the CSFV of the present invention and the use of the immunogenic composition for preventing and / or treating CSFV-related diseases in animals. In addition, the present invention provides a method or kit for distinguishing CSFV-infected animals from animals vaccinated with the immunogenic composition of the present invention. The present invention also provides an attenuated classical swine fever virus.

Various examples described herein are directed to systems and methods for providing a treatment substance to an animal. A server may receive from a user computing device an indication of the animal to be treated. The server may access an indication of a treatment substance to be provided to the animal and receive from the user computing device, a first current location of the user computing device. The server may determine that the first current location of the user computing device is more than a threshold distance from an expected location of the animal and, based on the determining that the first current location of the user computing device is more than a threshold distance from the expected location of the animal, send an alert message to an administrative user device.

There are provided a composition for preventing and treating heart disease due to pulmonary hypertension, and a functional preparation containing the same. The composition includes pimobendan, enalapril, torsemide, and spironolactone, and is thus effective in preventing and treating heart disease and pulmonary hypertension of animals.

The present invention relates to a composition for animals comprising a combination of one, two or more acid components and a binder. The binding agent comprises a tannin component and / or a polygalactose component. Further, the present invention relates to a composition for use as a pharmaceutical alternative, and in particular for use in the prevention and / or treatment of diarrhea in an animal. The invention also relates to the use of said composition for reducing the use of antibiotics and / or zinc oxide in animal breeding.

This application relates to compositions and methods used to treat animals with at least one microbial protein, such as a flagellin protein. In embodiments, application relates to compositions and methods to treat animals with a fusion protein comprising at least one adjuvant protein, such as a flagellin protein. In embodiments, the composition further includes at least one adjuvantic protein fused with at least one antigen protein, and the fusion protein is expressed in diatoms.