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275 results about "Feed additive" patented technology

A feed additive is a additive of extra nutrient or drug for livestock. Such additives include vitamins, amino acids, fatty acids, minerals, pharmaceutical, fungal products and steroidal compounds. The additives might impact feed presentation, hygiene, digestibility, or effect on intestinal health.

Antimicrobial feed additive

PendingUS20260144834A1BiocidePeptide/protein ingredientsChlamydomonas sajaoChlamydomonas reinhardtii
Feed additives including Chlamydomonas reinhardtii and a medium-chain fatty acid provide reduced risk of bacterial infection in animals. The feed additives are administered to animals in feed compositions.
Owner:AXITAN HOLDINGS INC

Newly isolated strain of neocallimastix and its application in preparation of feed additive for degrading coumarin

ActiveCN116555044BHigh efficiency in degrading coumarinEfficient degradationBiotechnologyNeocallimastix
This invention discloses a strain of *Neocallimastix* LGM-ZA9 and its application in the preparation of a coumarin-degrading feed additive. *Neocallimastix* LGM-ZA9 is classified as *Neocallimastix* sp., with accession number CGMCC No. 17592, and its optimal growth temperature is 39℃. The fermentation broth of *Neocallimastix* LGM-ZA9 can be used to degrade the anti-nutritional factor coumarin. The method is simple: the coumarin-containing material to be degraded is mixed with the fermentation broth, sterilized, and then the fermentation broth is added for anaerobic fermentation to degrade the coumarin. This preparation method is simple, highly operable, and can significantly reduce the coumarin content, providing a new method for feeding ruminants with sweet clover as a high-quality forage.
Owner:NANJING AGRICULTURAL UNIVERSITY

A fermented traditional chinese medicine feed additive for catfish and its preparation method and application

ActiveCN118160847BAntibacterial agentsFungiPaeonia suffruticosaBacterial disease
A fermented traditional Chinese medicine feed additive for catfish, its preparation method, and its application are disclosed, relating to the field of aquatic feed additives. The preparation method involves activating and expanding the culture of *Saccharomyces cerevisiae*, *Bacillus subtilis*, and *Lactobacillus plantarum*; pulverizing *Paeonia suffruticosa* leaves, *Smilax china*, *Scutellaria baicalensis*, *Rhus chinensis*, hawthorn, *Polygonum cuspidatum*, ginkgo, and forsythia suspensa* to obtain traditional Chinese medicine powders; preparing a solid fermentation medium using the traditional Chinese medicine powders, soybean meal powder, corn cob granules, and wheat bran; inoculating *Saccharomyces cerevisiae* seed culture and *Bacillus subtilis* seed culture for aerobic fermentation; and inoculating *Lactobacillus plantarum* seed culture for anaerobic fermentation to obtain the fermented traditional Chinese medicine feed additive. The resulting fermented traditional Chinese medicine feed additive promotes the absorption and metabolic elimination of enrofloxacin in catfish, shortens the withdrawal period, has preventive and adjunctive therapeutic effects on bacterial diseases in catfish, promotes growth, reduces feed conversion ratio, and improves survival rate.
Owner:LUOYANG NORMAL UNIV

A feed additive for improving intestinal health and preventing and treating intestinal diseases of animals and application thereof

PendingCN122439779ABiotechnologyIntestinal tract diseases
The application discloses a feed additive for improving intestinal health of animals and preventing and treating intestinal diseases and application thereof, and relates to the technical field of green and healthy breeding. The application firstly confirms that indole-3-butyric acid (IBA) has no toxic effect on cells and can relieve oxidative stress damage and inflammation damage of the cells in an effective concentration. Meanwhile, the application also fills the application blank of IBA as one of indole derivatives in livestock production, and provides experimental basis and theoretical basis for the fact that IBA is expected to be a new green additive for replacing antibiotics and zinc oxide. More importantly, the application also finds that IBA has positive effects in aspects of resisting diarrhea, repairing intestinal barrier damage, relieving intestinal inflammation and preventing and treating intestinal related diseases.
Owner:CHINA AGRI UNIV

A fermentation process and application of wheat germ

ActiveCN118303506BBiotechnologyWheat germ
This invention discloses a fermentation process and application of wheat germ, belonging to the field of feed additive technology. The fermentation process includes the following steps: mixing Bacillus coagulans powder (accession number CGMCC No. 1.17145), Lactobacillus salivarius powder (accession number CCTCC NO: M 2022848), and steam-sterilized and cooled wheat germ; performing solid-state fermentation in a sealed environment; and then sterilizing with ozone after fermentation to obtain fermented wheat germ. This invention produces highly nutritious fermented wheat germ through simple steps. This fermented wheat germ can be used as a feed additive for laying hens, improving their production performance.
Owner:HEBEI NORMAL UNIVERSITY OF SCIENCE & TECHNOLOGY +1

A high-efficiency feeder for feed additive production

This utility model belongs to the field of feed additive production technology, and in particular, a high-efficiency feeding machine for feed additive production. It includes a support frame, a shell, a screen frame, a support plate, a transmission plate, and a clamping plate. The shell is fixedly connected to the inner wall of the support frame, the screen frame is movably connected to the inner wall of the shell, the support plate is fixedly connected to the front side of the shell, and the transmission plate is slidably connected to the top of the support plate. There are two clamping plates, and two slots are provided on both the left and right sides of the screen frame. The two clamping plates engage with the corresponding slots. A clamping assembly is connected to the clamping plates and is used to fix the screen frame. This utility model, with its simple structure, facilitates the fixing or unlocking of the screen frame for installation or disassembly. The screen frame facilitates the screening of feed additives entering the shell, greatly improving the production quality of feed additives and demonstrating good practicality.
Owner:SHANDONG DELTA BIOENGINEERING CO LTD

A feed additive dosing device

This utility model discloses a feed additive dispensing device, including a storage container. A sealing gasket is provided on the top of the storage container, and a cover plate is provided on top of the sealing gasket. A heating box is fixedly connected to one side of the top of the cover plate, and a grid is provided at the bottom of the heating box. Multiple heating wires are installed inside the heating box. A blower is fixedly connected to one side of the storage container, and an air inlet pipe is fixedly connected between the blower and the heating box. This utility model heats the air inside the storage container by activating the heating wires, and simultaneously activates the blower to draw outside air into the air inlet pipe. This airflow achieves uniform heating of the additive, thereby drying the additive and ensuring proper storage. A humidity sensor is installed inside the storage container to detect the humidity of the additive for real-time monitoring.
Owner:XUCHANG YUKE BIOTECHNOLOGY CO LTD

Application of pyrrolquinoline quinone in relieving bluegill fish cyanotoxin poisoning

PendingCN122096291AOrganic active ingredientsAntipyreticQuinoneCyanotoxin
The application discloses application of pyrroloquinoline quinone (PQQ) or a derivative thereof in preparation of a product for relieving or preventing blue-green algae toxin poisoning of yellow catfish, and belongs to the technical field of aquatic animal feed. The PQQ or the derivative thereof can be used as an aquatic feed additive or a medicine, and is added in an amount of 3-6 mg / kg of feed to feed yellow catfish, so as to effectively relieve pathological damage of the liver of the yellow catfish caused by blue-green algae toxin through various ways such as improving key enzyme activity of liver function, inhibiting liver oxidative stress, relieving inflammatory reaction and reducing structural damage of tissues. The PQQ is a new food raw material approved in China in 2022, has advantages of high safety, good water solubility, moderate cost, similar dosage to that of feed vitamins and the like, and provides a safe, economical and convenient new nutritional intervention strategy for blue-green algae toxin poisoning of the yellow catfish, and has a wide industrial application prospect.
Owner:NEIJIANG NORMAL UNIV

A feed additive pellet cooling apparatus

ActiveCN224302806UReasonable structural designGood ventilation and heat dissipation structureClimate change adaptationDirect contact heat exchangersCold airFeed additive
The utility model discloses a kind of feed additive granule cooling equipment, including bearing base and cooling roller, the top end both sides of bearing base are vertically installed with support seat, the opposite side wall of two support seat is installed with carousel;The side wall of one side carousel is installed with fixed disc a, the side wall of the other side carousel is installed with fixed disc b, the cooling roller is assembled between fixed disc a and fixed disc b;The setting of this feed additive granule cooling equipment, structure design is reasonable;By setting cooling fin on the inner wall of cooling roller upper and lower two sides, and setting ventilation hole and assembling fan assembly outside drum, good ventilation and heat dissipation structure is formed.Fan assembly forced ventilation, cooperate cooling fin to increase heat dissipation area, so that feed additive granule can be in contact with cold air in the process of drum rotation, greatly improve cooling efficiency.
Owner:XUCHANG YUKE BIOTECHNOLOGY CO LTD

Compound grease feed additive for improving breeding quality of channa maculata and application of compound grease feed additive

The invention discloses a compound grease feed additive for improving breeding quality of channa maculata and application. The method comprises the following steps: (1) preparing experimental feed; the method comprises the following steps: respectively preparing an experimental group ARA 1.5 added with 1.5% of arachidonic acid and an experimental group ARA + PC added with 1.5% of arachidonic acid and 1.5% of phosphatidylcholine; (2) feeding; (3) after the culture experiment is finished, treating and detecting the channa maculata; (4) carrying out an artificial propagation test; (5) carrying out ovarian steroid synthesis related gene expression detection; and (6) carrying out data statistical analysis. By adding arachidonic acid (ARA) and phosphatidylcholine (PC) into the feed, the breeding performance of channa maculata and the quality of fry are improved, and the feed has very important significance for improving the aquatic product efficiency of high-quality fry of channa maculata in aquaculture.
Owner:PEARL RIVER FISHERY RES INST CHINESE ACAD OF FISHERY SCI

Boiling type drying bed equipment for producing feed additive selenium yeast

The utility model relates to the field of material drying equipment, and discloses boiling type drying bed equipment for feed additive selenium yeast production, which comprises a bottom plate, the top of the bottom plate is fixedly connected with a fixing frame, one side of the fixing frame is fixedly connected with a motor, the driving end of the motor is fixedly connected with a convex rod, and the convex rod is fixedly connected with a rotating shaft. The outer wall of the protruding rod is rotationally connected with a rotating rod, one end of the rotating rod is rotationally connected with a connecting rod, the top of the connecting rod is slidably connected with a limiting block, the top of the limiting block is fixedly connected with a fine material screening plate, and the top of the fine material screening plate is fixedly connected with a medium material screening plate. The motor is started, the driving end of the motor drives the protruding rod to rotate, then the rotating rod is driven to reciprocate in the vertical direction, and the reciprocating motion of the rotating rod is transmitted through the connecting rod, so that the clamping head on the top of the connecting rod moves in the limiting block and pushes the limiting block to move.
Owner:ZHEJIANG DEQING DONGLI BIOLOGICAL DEV

A lactation enhancing functional feed for lactating sows containing a high efficiency plant lactogenic factor

PendingCN122250581AChanging exchange dynamicsProlong the action timeAnimal feeding stuffAccessory food factorsBiotechnologyAnimal science
The present application relates to the technical field of feed additive, and discloses a lactation-promoting functional feed for lactating sows containing high-efficiency plant lactogenic factors, which is made of the following raw materials: sodium-based montmorillonite, fenugreek extract, motherwort extract, ion intensity regulator, lysophosphatidylcholine, tributyl citrate and high-purity silicon dioxide, and is prepared through the following steps: mixing and drying sodium-based montmorillonite with the ion intensity regulator to prepare a regulation carrier; adding fenugreek and motherwort extract and mixing them by strong shearing to form an active core; atomizing and spraying a mixture of lysophosphatidylcholine and tributyl citrate on the surface of the core to form a functional layer; and finally adding high-purity silicon dioxide and mixing uniformly to obtain the feed. Through the construction of the structure with ion-pretreated montmorillonite as the core and the functional layer as the shell, the present application realizes the protection, sustained release and efficient absorption of the active ingredients, and improves the bioavailability.
Owner:YUNNAN MEIXIN AGRICULTURE & ANIMAL HUSBANDRY TECHNOLOGY CO LTD

Feed additive and method for its preparation, feed

The application provides a feed additive and a preparation method thereof, and feed. The preparation method of the feed additive comprises the following steps: carrying out rubbing treatment on fresh mulberry branches to prepare a filamentous material; mixing the filamentous material with mulberry pomace and a leavening agent to prepare a mixture; carrying out fermentation treatment on the mixture to prepare a fermentation product; and sequentially carrying out ultrasonic extraction, concentration, drying and crushing on the fermentation product to prepare the feed additive. The preparation method of the feed additive expands the utilization mode of mulberry resources.
Owner:INST OF ANIMAL SCI & VETERINARY HUBEI ACADEMY OF AGRI SCI

Packaging bag (feed additive)

1. Name of the designed product: packing bag (feed additive). 2. Use of the designed product: packing bag for feed additive. 3. Design points of the designed product: combination of shape and pattern. 4. Picture or photo showing the design points: design 1 perspective view. 5. Design 1 is designated as the basic design.
Owner:XUAI (HENAN) BIOTECHNOLOGY CO LTD

A feed additive raw material impurity filtering device

The utility model relates to the field of feed production and processing, concretely discloses a feed additive raw material impurity filtering device, including filter cylinder, feeding structure, two supports and motor, two supports divide into feeding support and unloading support, and feeding structure is installed on the feeding support, and the left and right sides of filter cylinder are connected with feeding structure and unloading support rotation respectively, and the motor is installed on the feeding support and is connected with filter cylinder, and the feed additive raw material is filtered through the use filter cylinder, not only can carry out the filtering operation quickly, and compared with the current with a layer of screen cloth carries out the screening, not only can carry out multiple screening, make the screening be more thorough, and compared with the traditional screen screening, the filter cylinder can return the impurity or feed additive raw material stuck in the filter hole to the filter cylinder and carry out 2 screenings when rotating.
Owner:AINI BIOTECHNOLOGY (ZHENJIANG) CO LTD

Fattening feed additive composition for old-piece cattle and fattening method

The invention discloses a fattening feed additive composition for old cattle and a fattening method, and belongs to the technical field of feed. The additive composition comprises the following components in parts by weight: 13-20 parts of a rumen function regulator, 4-10 parts of an intestinal repair agent, 10-20 parts of a rumen bypass compound enzyme preparation, 5-10 parts of a muscle-increasing growth-promoting composition, 5.5-7.3 parts of a functional trace element composition and 32.7-62.5 parts of a carrier. Wherein the rumen function regulator is compounded by a coated saccharomyces cerevisiae culture and bacillus subtilis; the rumen bypass compound enzyme preparation comprises acid protease, neutral protease and cellulase; the muscle-building and growth-promoting combination is coated guanidinoacetic acid. Through regulation and control of a rumen-intestinal tract-tissue three-level linkage network, the rumen fermentation function of the old cattle is remarkably improved, the feed conversion rate is increased, and meanwhile muscle hyperplasia and meat tenderization are achieved. By means of the fattening method, the average daily gain of the old cattle is increased by 22.8% or above, the muscle shear force is reduced by 29.6% or above, the feed conversion ratio is reduced by 17.1% or above, and green and efficient fattening is achieved.
Owner:JILIN XINFANGYUAN GRASSLAND FARMING TECH CO LTD

Use of 4-hydroxyphenylacetic acid in the preparation of a feed additive for young pigeons

PendingCN122439778ABiotechnologyAnimal science
The application belongs to the technical field of pigeon feed, and particularly relates to application of 4-hydroxyphenylacetic acid in preparation of a milk pigeon feed additive. A method for improving the growth performance and immune performance of a milk pigeon is provided, which comprises: additionally adding 4-hydroxyphenylacetic acid in milk pigeon milk replacer. Experiments prove that, after 500-2000 mg / kg of 4-hydroxyphenylacetic acid is additionally added in the milk pigeon milk replacer, the growth performance and immune performance of the milk pigeon are obviously enhanced, and the survival rate of the milk pigeon is improved, which has important significance for the large-scale breeding of meat pigeons.
Owner:BEIJING ACADEMY OF AGRICULTURE & FORESTRY SCIENCES

Preparation method and application of a composition for promoting growth and resisting inflammation of egg chicks

PendingCN122297567ABiotechnologyAnimal science
This invention relates to a method for preparing and applying a composition for promoting growth and reducing inflammation in laying chicks, belonging to the field of veterinary feed additives. The components and their weight ratios are as follows: 20-30 parts of Codonopsis pilosula extract, 15-25 parts of Astragalus membranaceus extract, 10-20 parts of Tartary buckwheat extract, 10-20 parts of Elsholtzia ciliata extract, 3-5 parts of zinc sucrose, 2-3 parts of emulsifier, and 1-2 parts of stabilizer. First, the four extracts of Codonopsis pilosula, Astragalus membranaceus, Tartary buckwheat, and Elsholtzia ciliata are concentrated, spray-dried, and then mixed evenly with zinc sucrose, emulsifier, and stabilizer using a three-dimensional mixer to obtain the composition for promoting growth and reducing inflammation in laying chicks. This composition can significantly improve the growth performance of laying chicks, enhance their immunity, effectively prevent and control inflammatory responses, and improve survival rate and feed conversion rate. It is suitable for laying chick farming and has broad market application prospects.
Owner:TIANJIN HLINTE BIOTECH CO LTD

Application of fagopyrum cymosum root powder in preparation of products for improving egg quality or intestinal health of laying ducks

ActiveCN120753340BBiotechnologyYolk
The application discloses application of Fagopyrum cymosum root powder in preparation of products for improving egg quality or intestinal health of laying ducks, and belongs to the technical field of feed additives. The application provides application of Fagopyrum cymosum root powder in preparation of products for improving egg quality or intestinal health of laying ducks, and the Fagopyrum cymosum root powder can improve eggshell strength, yolk color and eggshell proportion, improve the content of aspartic acid, threonine, glutamic acid, glycine, cystine and leucine in yolk, improve the content of arachidonic acid and arachidonic acid in yolk, and reduce the content of saturated fatty acid in yolk; the Fagopyrum cymosum root powder can improve the activity of maltase in the mucous membrane of the jejunum of laying ducks, and can improve the diversity and abundance of intestinal flora of laying ducks. The application provides a new strategy for improving egg quality or intestinal health of laying ducks.
Owner:INST OF ANIMAL HUSBANDRY & VETERINARY MEDICINE JIANGXI ACAD OF AGRI SCI

Feed additive, method for preparing the same and use thereof

The present application relates to the field of feed additive, and discloses a feed additive, a preparation method and application thereof.The feed additive contains astaxanthin, curcumin, vitamin C palmitate, vitamin E, vitamin D3, piperine and a carrier.The preparation method comprises the following steps: mixing astaxanthin, curcumin, vitamin C palmitate, vitamin E, vitamin D3, piperine and the carrier.The feed additive can significantly improve the stress resistance, immunity, antioxidant capacity and disease resistance of aquatic animals, and has significant economic benefits.
Owner:HANGZHOU ZHIJUN HIGH TECH TECHNOLOGY CO LTD

A Bacillus subtilis composition for improving animal gut health and its preparation method

This invention relates to the field of feed additive technology, specifically to a Bacillus subtilis composition for improving animal intestinal health and its preparation method. It comprises the following raw materials: Bacillus subtilis engineered bacterial powder, cinnamaldehyde microcapsules, proanthocyanidins B2, selenium-enriched yeast culture, glycoterpenes, trehalose, and a carrier. The core of this invention lies in using Bacillus subtilis EhrBS-9 (CGMCC No. 24947) as the strain, constructing a dual-function engineered bacterium with tolerance and transformation through gradient cinnamaldehyde domestication and cad gene integration. This, combined with the intestinal-targeted delivery of cinnamaldehyde microcapsules, barrier strengthening of proanthocyanidins B2, and the construction of a multidimensional anti-stress network of selenium-enriched yeast, glycoterpenes, and trehalose, forms a synergistic mechanism of gut microbiota regulation, immune enhancement, and stress buffering. This addresses the industry pain point of insufficient synergistic effects of existing feed additives in terms of high-efficiency antibacterial activity, safe immune regulation, root-cause anti-stress, and ecological safety.
Owner:BEIJING DORUN TECH

Application of ginseng extract in preparation of feed additive for resisting infection of aeromonas hydrophila

ActiveCN120036423BAntibacterial agentsAnimal feeding stuffGINSENG EXTRACTImmunoglobulin levels
The application discloses application of Gastrodia elata extract in preparation of a feed additive for resisting Aeromonas hydrophila infection, and belongs to the technical field of water animal disease prevention and treatment. The application first finds that the Gastrodia elata extract has a significant effect of inhibiting Aeromonas hydrophila infection. After the Gastrodia elata extract is added into water animal feed as a feed additive and is fed to the water animal, the Gastrodia elata extract is absorbed into blood circulation system through a digestive tract, up-regulates intestinal immunoglobulin gene expression, improves serum immunoglobulin level, enhances intestinal barrier function, improves animal activity, effectively resists Aeromonas hydrophila infection, reduces disease occurrence, and improves yield and quality of animal breeding. Therefore, the Gastrodia elata extract has a good application prospect.
Owner:HUAZHONG AGRI UNIV +1

A feed lactic acid bacteria additive and a preparation method thereof

ActiveCN121986869BBiotechnologyCarrageenan
The present application relates to the technical field of microbial feed additive, and discloses a feed lactic acid bacteria additive and a preparation method thereof.The preparation method comprises the following steps: taking Lactobacillus plantarum and / or Enterococcus faecalis as a bacterial strain to activate and expand culture, taking agricultural and sideline product waste as a substrate to obtain mature fermentation liquor through deep liquid fermentation; mixing the mature fermentation liquor with a composite protective agent containing double essential oil, chitosan, theabrownin and porous silicon dioxide to obtain a semi-dry granule core through granulation and low-temperature pre-drying; and coating the semi-dry granule core with a κ-carrageenan / konjac glucomannan / plant sterol ester composite gel, and drying and packaging to obtain a finished product.The double essential oil, chitosan and theabrownin jointly form a full-spectrum active antibacterial system; the elastic composite gel outer layer realizes dual protection of liquid water and water vapor; the porous silicon dioxide actively maintains low water activity of the granule to prevent the lactic acid bacteria from recovering in advance; and the product has high viable count, strong heat and acid resistance, and excellent storage stability.
Owner:JILIN UNIVERSITY

A feed additive containing mulberry leaves, and a preparation method and application thereof

The application provides a feed additive containing mulberry leaves and a preparation method and application thereof, and belongs to the technical field of feed additives.The feed additive contains the following raw materials in parts by weight: fresh mulberry leaves 50-70 parts, corn flour 5-15 parts, molasses 1-2 parts, rapeseed cake 2-4 parts, wheat bran 15-25 parts and fermentation agent 0.1-0.5 parts.The application can significantly improve the body antioxidant function and immune level of fattening pigs, improve the fatty acid composition of pork, increase the content of unsaturated fatty acids, oleic acid and iron elements, reduce the total amount of saturated fat and muscle bitter amino acids, and improve the pork quality and nutritional value.
Owner:GUIZHOU SERICULTURE RES INST GUIZHOU PEPPER RES INST +1

Use of sodium butyrate in the preparation of feed additive against salmonella pullorum

PendingCN122439777ABiotechnologyT cell
The application belongs to the field of feed additives, and particularly discloses application of sodium butyrate in preparation of a feed additive against chicken white dysentery Salmonella, and sodium butyrate is added in chicken basic feed as the feed additive against chicken white dysentery Salmonella; the addition of sodium butyrate in chicken basic feed can significantly reduce the bacterial load of chicken white dysentery Salmonella infection in chicken liver and spleen, significantly increase the ratio of villus length to crypt depth of the cecum of chicken infected with chicken white dysentery Salmonella, and improve the intestinal absorption capacity; the content of CD3+ T cells, TCR+ T cells, macrophages and B cells in the liver of chicken infected with chicken white dysentery Salmonella can be significantly reduced; and then the body weight of chicken infected with chicken white dysentery Salmonella is significantly increased, and the survival rate of chicken infected with chicken white dysentery Salmonella is increased. In summary, the addition of sodium butyrate in chicken basic feed can enhance the resistance to chicken white dysentery Salmonella infection.
Owner:ANIMAL SCI RES INST GUANGDONG ACADEMY OF AGRI SCI

A device for solving the problem of residual discharge of a cone-type coating machine

ActiveCN224410873UDoes not affect productivityperformance is not affectedChemical industryProcess engineering
The utility model relates to a device that solves the problem of residual material in a cone-type coating machine, especially for fluidized coating machine, belongs to the field of feed additive, medicine, chemical industry, material, food equipment, including sliding mechanism, the sliding mechanism sets up in the coating cylinder wall inside, be provided with the spray gun on the sliding mechanism, the spray gun is under the action of sliding mechanism and slides below the ventilated chassis, to clean the residual material. This structure design can efficiently remove the residual material, and also ensures the product quality on the basis of improving the production efficiency.
Owner:SUZHOU MEINONG BIOTECHNOLOGY CO LTD

Microencapsulated spray-dried 25-hydroxyvitamin d3 and methods of making same

The present application relates to the field of functional nutritional fortifier micro-encapsulation technology, and discloses a kind of micro-encapsulated spray-dried 25-hydroxyvitamin D3 and its preparation method.The microcapsule is composed of 25-hydroxyvitamin D3, synergistically modified embedding matrix material, isophorone diisocyanate derived biuret small molecule and various additives, wherein the synergistically modified embedding matrix material is formed by casein and hydroxypropyl-beta-cyclodextrin under the action of covalent bridging, aromatic amine crosslinking network and boron-nitrogen synergistic coordination to form a dynamic covalent-supramolecular coupled multi-network structure.Through the synergistic effect of the multi-network structure and the interface self-assembly small molecule, the multiple confinement and interface stable regulation of 25-hydroxyvitamin D3 are realized.The preparation method includes the construction of synergistically modified embedding matrix material, emulsification and spray-drying steps.The microcapsule product obtained by the present application has the advantages of high embedding rate, strong thermal stability, excellent antioxidant performance and controllable release behavior, and is suitable for food fortification and feed additive fields.
Owner:SHANDONG HAINENG BIOENG CO LTD

The use of β-glucuronidase in the preparation of an antidote for the prevention and / or treatment of zearalenone poisoning, and an antidote for the prevention and / or treatment of zearalenone poisoning.

ActiveCN121606700Breduce exposureClear technical pathOrganic active ingredientsAntinoxious agentsEnzyme Inhibitor AgentGlucuronidase Inhibitor
This invention provides the use of β-glucuronidase in the preparation of an antidote for the prevention and / or treatment of zearalenone poisoning, and an antidote for the prevention and / or treatment of zearalenone poisoning, belonging to the field of feed additives. This invention, for the first time from the perspective of in vivo exposure control in animals, proposes a method to reduce the overall ZEN exposure level by inhibiting the activity of intestinal bacterial β-glucuronidase. The technical path is clear and highly operable. This is achieved through in vivo toxicokinetic parameters (AUC, C...). max Changes in (and / or MRT) objectively reflect a reduction in ZEN exposure levels in vivo, and the technical effects are quantifiable and verifiable. The β-glucuronidase inhibitors used in this invention are widely available, particularly suitable for the field of feed additives, and have promising application prospects.
Owner:INSTITUTE OF ANIMAL SCIENCES OF CHINESE ACADEMY OF AGRICULTURAL SCIENCES