1306 results about "Antioxidant capacity" patented technology

The invention provides isolated Ackermansiella muciniphila, a composition containing the same and an anti-aging and / or anti-oxidation application of the Ackermansiella muciniphila. The Akkermansia muciniphila has the advantages that the average life and the longest life of the Akkermansia muciniphila in a nematode model can be prolonged, the movement activity, the swallowing function and the reproductive capacity of the Akkermansia muciniphila can be improved, the expression of insulin / IGF-1 pathway genes (daf-16, daf-2 and age-1), the expression of antioxidant genes (gst-4 and sod-3) and the expression of longevity related genes (sir-2.1) of the Akkermansia muciniphila can be up-regulated, and the antioxidant capacity and the heat stress tolerance of the Akkermansia muciniphila can be enhanced. It is shown that the Akkermansia muciniphila provided by the invention can be used for preparing or developing the anti-oxidation and anti-aging products, and the anti-oxidation and anti-aging products can be prepared from the Akkermansia muciniphila. The invention provides an efficient and safe solution for anti-aging and / or anti-oxidation.

The invention belongs to the technical field of microbial fermentation, and particularly relates to lactobacillus rhamnosus capable of maintaining bone health and improving local joint inflammation and a metagen and application of the lactobacillus rhamnosus. According to the invention, the probiotic NKU ML1-2 is subjected to fermentation culture, such that a post-generation product is prepared. Results of embodiments prove that the metagen product can enhance the oxidation resistance of cartilage and osteoblasts and promote the synthesis of anti-inflammatory factors and cartilage matrixes (type II collagen and proteoglycan), and has the potential of relieving oxidative stress and inflammatory response of local joints, relieving joint inflammation and delaying cartilage destruction. The prepared metagen product is high in safety and good in stability, and can be applied to preparation of medicines for preventing and / or treating osteoarthritis; the metagen product can also be used for promoting bone health, enhancing the antioxidant capacity of osteoblasts and / or chondrocytes, promoting osteoblast activity and / or promoting calcium absorption and fixation, and a new solution is provided for joint health management.

The invention belongs to the technical field of cosmetic production, and discloses an anti-wrinkle composition and a preparation method and application thereof as well as cosmetics, the anti-wrinkle composition comprises a flos magnoliae extract and an emblic leafflower fruit extract, and the mass ratio of the flos magnoliae extract to the emblic leafflower fruit extract is (0.1-8): (0.5-10); through the synergistic effect of flos magnoliae and fructus phyllanthi contained in the composition, the composition not only has good elastinase inhibition ability, but also has excellent antioxidant ability, so that the composition has good elastinase inhibition ability and good free radical scavenging ability, and further achieves good anti-wrinkle performance.

The invention discloses an ulva lactuca composite wall-breaking enzymolysis fermentation product as well as a preparation method and application thereof, and relates to the field of cosmetics. The preparation method comprises the following steps: soaking ulva powder, and performing physical cell wall breaking treatment; mixed enzymes are added for an enzymolysis reaction, wherein the mixed enzymes comprise lipase, cell wall breaking enzyme, enzyme and protease; adding the enzymolysis product into a culture medium, and inoculating bacterial liquid for fermentation culture to obtain fermentation liquid. According to the application, active ingredients such as macromolecular polysaccharide and protein in the ulva lactuca are extracted and decomposed by adopting physical cell wall breaking, composite enzymolysis and bifidus yeast fermentation technologies, and the prepared fermentation product is rich in various composite micromolecular active ingredients such as oligosaccharide, polypeptide, amino acid, polyphenols and flavonoids, has high free radical scavenging capacity, and can be used for preparing the ulva lactuca beverage. The anti-wrinkle and anti-oxidation composition has good anti-wrinkle and anti-oxidation effects, is beneficial to skin absorption when being applied to cosmetics and has high absorption efficiency, and the prepared cosmetics have excellent anti-wrinkle, anti-oxidation, soothing and repairing effects.

The invention provides a microbial source anti-oxidation pigment feed additive for aquaculture and a preparation method of the microbial source anti-oxidation pigment feed additive, the microbial source anti-oxidation pigment feed additive for aquaculture is prepared by the following steps: carrying out low-temperature plasma physical mutagenesis on talaromyces albuminosus CY-G to generate a mutant strain, namely talaromyces albuminosus CY110, and then carrying out semi-solid state fermentation on the mutant strain, namely talaromyces albuminosus CY110 to produce wine red pigment. The pigment product obtained by the invention is high in yield of haematochrome, orange pigment and yellow pigment, low in citrinin content, stable in property and relatively strong in oxidation resistance, can be used as an aquaculture microorganism source anti-oxidation pigment feed additive, and has a wide application prospect. The preparation method disclosed by the invention is simple to operate, low in equipment requirement, high in production efficiency and suitable for large-scale production.

The present invention provides a phycocyanin-collagen composite hydrogel and its preparation method and application. The present invention utilizes transglutaminase to catalyze the combination of phycocyanin and collagen to form a new, more stable collagen; transglutaminase acts between protein molecules, utilizes lysine and glutamic acid in phycocyanin and collagen to transfer acyl groups, and cross-links to form new chemical bonds, thereby enhancing the binding strength of phycocyanin and collagen; the hydrogel prepared by the present invention can be used to prepare medical materials and combined with skin injury sites to solve the problem that traditional dressings are easy to adhere to wounds and easily penetrated by tissue fluid and become infected. In addition to ensuring basic air permeability, it reduces the adhesion of the dressing, increases moisture retention and antioxidant properties, and avoids secondary damage when replacing a new dressing. The hydrogel prepared by the present invention has a certain antioxidant capacity and can be used to prepare products with antioxidant effects.

The invention provides a novel enterococcus strain Enterococcus qinghaiensis SCFF543 and an anti-oxidation application of the novel enterococcus strain Enterococcus qinghaiensis SCFF543, and belongs to the technical field of microorganisms. Wherein the strain is preserved in the China General Microbiological Culture Collection Center (CGMCC) on June 10, 2025, and the preservation number is CGMCC No.34843. The invention further discloses a preparation method of the strain. The strain is separated from homemade casein of herdsman families in Demaoha City in Haixi, Qinghai province, has the advantages of strong antioxidant capacity, no vancomycin resistance, strong adhesiveness and the like, and can be suitable for preparing probiotic products with antioxidant effects.

The invention relates to the technical field of health-care food, in particular to a composition capable of improving water retention and water locking capacity of skin and a preparation method of the composition. Comprising the following steps: preparing starch salmon nasal cartilage composite nano powder; preparing flavor moisturizing tremella polysaccharide fermentation liquor; and light enzymolysis of the salmon nasal cartilage and compounding of the salmon nasal cartilage and the tremella polysaccharide fermentation liquor. According to the invention, the lactobacillus kefiranofaciens kluyveromyces marxianus subsp. Kefiranofaciens ZW3 bacterial liquid, the kluyveromyces marxianus bacterial liquid and the bacillus subtilis DE111 bacterial liquid which are activated and propagated according to a certain proportion are mixed to prepare the compound bacterial liquid, and then the tremella fuciformis extracting solution is fermented, so that the flavor and taste of the tremella fuciformis extracting solution can be improved, the fermentation effect can be enhanced, and the quality of the tremella fuciformis is improved. Healthy nutritional ingredients such as microbial protein, vitamins and amino acid can be efficiently generated, the antioxidant capacity is enhanced, and the prepared flavored moisturizing tremella polysaccharide fermentation liquor is rich in nutritional ingredients and can improve the antioxidant capacity and the water retention and moisturizing capacity of human skin after being taken into a human body.

The invention discloses a lactobacillus rhamnosus strain with antiallergic activity and a preparation method thereof, the strain is lactobacillus rhamnosus Lrn-PG-06, the classification name of the strain is Lactobacillus rhamnosus, the preservation number is CGMCC (China General Microbiological Culture Collection Center) No.3077, the preservation time is March 21, 2024, the preservation unit is China General Microbiological Culture Collection Center, the preservation number is CGMCC No.3077, and the preservation number is CGMCC No.3077. The address is No.3, Yard 1, Beichen West Road, Chaoyang District, Beijing. The lactobacillus rhamnosus Lrn-PG-06 strain is high in acid resistance, alkali resistance and cholate resistance, high in simulated gastrointestinal fluid resistance and high in oxidation resistance, has the advantage of resisting allergy, and solves the problems that at present, allergic diseases are mainly treated by drugs or are prevented from being in contact with allergens in the environment and food, but due to the fact that the drugs are large in toxic and side effects, the allergens cannot be in contact with the allergens in the environment and food. And allergens causing anaphylaxis are difficult to determine, so that allergic diseases are difficult to treat or prevent.

The present invention discloses a strain of Lactobacillus paracasei that simultaneously activates immune regulation and antioxidant pathways to alleviate vaginitis, belonging to the field of microbial technology. The present invention screened and obtained a strain of Lactobacillus paracasei CCFM1316, which has the effect of repairing related symptoms such as immune disorders and oxidative damage caused by vaginitis, specifically embodied in: reducing cellular NF-κB mRNA expression and cell supernatant IL-1β content, improving mouse vaginal immune response, enhancing mouse vaginal antioxidant capacity, improving mouse vaginal pathological manifestations and reducing pathogenic bacteria load. It reduces the mouse vaginal Gardnerella load and improves mouse vaginal pathological manifestations; therefore, Lactobacillus paracasei CCFM1316 has great application prospects in products that improve and repair immune disorders and oxidative damage problems caused by vaginitis.

The invention relates to the technical field of breeding feed, and discloses an efficient feed additive based on emblic leafflower residue component optimization and a preparation method thereof. Comprising the following components in parts by weight: 30-60 parts of emblic leafflower residues, 10-20 parts of amino acids, 5-15 parts of a vitamin premix, 3-8 parts of a mineral premix, 5-20 parts of probiotics, 0.6-4 parts of cellulase, 0.45-3 parts of pectinase and 0.75-4 parts of amylase. By adding the emblic leafflower residues, the nutrition of the feed additive is enriched, the emblic leafflower residues are rich in cellulose, polyphenol, flavone and other components, have an antioxidant effect, can help animals to remove free radicals in bodies, enhance the antioxidant capacity of the bodies and improve the immunity, meanwhile, the emblic leafflower residues are wide in source and relatively low in cost, and as a feed additive component, the feed cost is reduced; the resource utilization rate and culture benefits are improved.

The invention provides a preparation method of Keemun camellia seed fermented oil, and belongs to the technical field of vegetable oil production. The preparation method comprises the following steps: S1, preparing recombinant saccharomycetes; s2, jointly fermenting the antarctic torulopsis, the recombinant saccharomycetes and the Keemun camellia seed oil; s3, separating an oil phase from a water phase, and taking the oil phase; and S4, dehydrating the oil phase to obtain the Keemun camellia seed fermented oil. Preferably, according to the preparation method of the recombinant saccharomycetes in the step S1, phenylalanine deaminase, cinnamate hydroxylase, 4-coumaric acid CoA ligase, chalcone synthetase, chalcone reductase and peroxidase are expressed in saccharomyces cerevisiae. According to the Keemun camellia seed fermented oil prepared by the method disclosed by the invention, the characteristic components of the Keemun camellia seed oil can be remarkably improved, the antioxidant capacity of the Keemun camellia seed oil is enhanced while the skin feeling of the Keemun camellia seed oil is improved, and the application value of the Keemun camellia seed oil in cosmetics is improved.

The invention relates to the field of traditional Chinese medicine compositions, in particular to a composition for dispelling effects of alcohol and protecting liver and application. The composition for dispelling the effects of alcohol and protecting the liver comprises the following raw materials: 1-4 parts of calculus bovis factitius, 1-4 parts of artificial bear gall, 35-55 parts of a pseudo-ginseng extract, 40-60 parts of a herba artemisiae scopariae extract, 50-70 parts of a rhizoma smilacis glabrae extract, 30-50 parts of a polygonum cuspidatum extract, 30-50 parts of a radix paeoniae alba extract, 70-90 parts of a pueraria flower extract, 40-60 parts of a rhizoma polygonati extract and 40-60 parts of a dark malt extract. And 25-35 parts of a fructus amomi extract. The hangover-alleviating and liver-protecting composition has the advantages that the hangover-alleviating and liver-protecting effects are similar to that of a positive medicine Haiwang Jinvessel for relieving rat body mass reduction caused by an acute drunkenness model, the hangover-alleviating rate within 6 hours and the liver-protecting and anti-oxidation effects are similar to that of a positive medicine Haiwang Jinvessel, the body mass improvement effect, the hangover-alleviating rate and the anti-oxidation capability of a body are better, and the hangover-alleviating and liver-protecting composition has good development and application values.

The invention discloses application of bifidobacterium adolescentis CCFM1302 in promoting synthesis of host collagen, and belongs to the technical field of microorganisms and medicines. The metagen of the bifidobacterium adolescentis CCFM1302 disclosed by the invention has a good effect of regulating and controlling synthesis and degradation of collagen, the moisture and elasticity of the skin are improved, the antioxidant capacity of the skin is improved, the inflammation level of an organism is reduced, and the stable state of collagen is maintained. The method specifically comprises the following steps: in vitro promoting the enzyme activity of HSF cell LH1 by a thallus lysate, inhibiting the enzyme activity of MMP-3, increasing the content of COL I and COL III and the enzyme activity of LH1, P4H and LOX from the outside of a fermented supernatant, and inhibiting the enzyme activity of MMP-3; the inactivated thalli are orally taken to increase the collagen content and the enzyme activity of LH1 and inhibit the enzyme activity of MMP-1 and MMP-3; the fermentation supernatant is orally taken to inhibit enzyme activity of MMP-3 and MMP-1 and degradation of collagen, and the content of TGF-beta is increased.

The invention discloses a manganese / cobalt-based MOFs nano-enzyme with a hollow structure as well as a preparation method and application thereof, and belongs to the technical field of preparation and application of novel nano-materials. According to the invention, ZIF-67 is used as a carrier, potassium permanganate is used as a manganese source, and the Mn / Co-MOF nano-enzyme with a hollow structure and highly dispersed manganese species is prepared through a loading-low temperature pyrolysis strategy. The antioxidant substances in the black tea can inhibit the oxidase-like activity of the hollow-structure manganese / cobalt-based MOFs nano-enzyme, so that the color of the system is changed, and based on the principle, the method for detecting the total oxidation resistance of the tea based on the hollow-structure manganese / cobalt-based MOFs nano-enzyme is established. Meanwhile, the method is used for monitoring the change of the total antioxidant capacity in the black tea fermentation process, a new method for judging the fermentation degree of the black tea is established in combination with data processing methods such as machine learning, and a new means is provided for improving the quality of the black tea and intelligently processing tea leaves.

The invention belongs to the technical field of functional food, and discloses a multifunctional Chinese yam composite peptide composition, a preparation method and application in the aspect of strengthening the heart, the preparation method of the multifunctional Chinese yam composite peptide composition comprises the following steps: preparing pea protein powder; preparing pea peptide powder A; and preparing the multifunctional Chinese yam composite peptide composition. The high-activity pea peptide powder and the Chinese yam powder are subjected to wet graft copolymerization, polysaccharide in the Chinese yam can effectively neutralize the bitter taste of pea peptide, the hydrolysis rate of the pea peptide is increased to 94.32% under the condition that the pH is 2.0-3.0, meanwhile, the oxidation resistance and the gastric mucosa protection capacity of the pea peptide are remarkably improved, the hygroscopicity is improved, and the water content is 8.79%.

The invention discloses a Pediococcus pentosaceus strain and an application thereof. Belongs to the technical field of functional component conversion. According to the content of total saponin and polysaccharide in American ginseng, a lactic acid bacterium capable of efficiently converting saponin and polysaccharide is screened by taking a comprehensive score as an index, is identified as pediococcus pentosaceus through morphology, physiology, biochemistry and molecular biology and is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.33430. The contents of total saponins in the transformed American ginseng and ginseng are respectively increased by 53.90% and 209.61%, and the contents of polysaccharides are respectively increased by 124.68% and 68.16%. The DPPH antioxidant capacity, the ABTS antioxidant capacity, the blood sugar reducing capacity and the blood fat reducing capacity of the converted American ginseng and ginseng total saponin extracting solution and the polysaccharide extracting solution are all improved. The pediococcus pentosaceus obtained by screening has a wide application prospect.

The invention belongs to the technical field of biological medicines, and particularly discloses a composition with functions of reducing blood sugar and blood fat as well as a preparation method and application of the composition. Chinese herbal compound medicinal materials are subjected to water extraction and high-temperature and high-pressure sterilization, and lactobacillus rhamnosus SHA113 bacterial sludge is resuspended in a water extract to obtain the composition of lactobacillus rhamnosus SHA113 and the Chinese herbal compound; the traditional Chinese medicine compound composition comprises astragalus membranaceus, raw Chinese yam, hawthorn, gynostemma pentaphylla, liquorice and jujube; the preservation number of the lactobacillus rhamnosus SHA113 is CCTCC (China Center For Type Culture Collection) NO: M 2017838; the lactobacillus rhamnosus SHA113 and traditional Chinese medicine compound composition can remarkably reduce the content of triglyceride and cholesterol in serum, control the fasting blood-glucose level, relieve accumulation of triglyceride and cholesterol in the liver and improve the oxidation resistance of the liver, has wide market potential and application prospects, and has wide application prospects. The compound can be applied to preparation of drugs for reducing blood sugar and blood fat.

The invention relates to the technical field of genetic engineering and biological agents, in particular to a hybrid peptide with immunoregulation and anti-oxidation functions and a preparation method and application of the hybrid peptide. The polypeptide provided by the invention has immunoregulation and antioxidation functions at the same time, and in a normal or immunosuppression state, the polypeptide can significantly improve the immunologic function of a body and reduce the damage of immunosuppression to the body; the oxidation resistance of cells and organisms can be enhanced; meanwhile, the polypeptide has the advantages of low cytotoxicity, high safety, simplicity and convenience in preparation and low cost, can be used as an ideal immunomodulator and an antioxidant, is widely applied to the fields of medicines, foods, health care, feeds, nutrition and the like of human and animals, and has very good application potential and value.

The invention discloses a kind of high-efficiency and environment-friendly developer for PCB board, and the developer includes the following components by mass: 60-100 parts of organic alkali composition; 30-80 parts of cosolvent; 30-70 parts of defoamer; 40-70 parts of surfactant; 20-50 parts of antioxidant; 15-45 parts of penetrant; 30-50 parts of buffer; 10-20 parts of inhibitor; The invention also discloses a preparation process of high-efficiency and environment-friendly developer for PCB board. The present invention develops PCB board by using organic alkali composition, fully dissolves dry film by ether group, hydroxyl group and amine group, avoids solid precipitation caused by traditional carbonate development, thereby effectively improving the efficiency and quality of PCB development process; penetrant and cosolvent are added at the same time, significantly improving the penetration and dissolution effect of developer on dry film, further improving development efficiency; and with the antioxidant, buffer etc. added therein, the antioxidant capacity of developer and PCB board can be improved, and the stability of developer during use is ensured.

The invention relates to the field of animal feed science and processing, and discloses an efficient fattening type compound feed for meat gamegalors and a preparation method thereof.The preparation method includes the steps that firstly, specific compound plant raw materials and screened compound dominant flora are adopted for multi-step solid-state symbiotic fermentation, and a fermentation base material rich in probiotics, small molecule peptides and low anti-nutritional factors is prepared; secondly, core functional components including high-activity probiotics, plant extracts, functional lipids, antioxidants and the like are subjected to targeted sustained-release microcapsule coating through a multi-layer composite material; and finally, mixing the fermentation base material with targeted slow-release microcapsules and other conventional feed components, and preparing the compound feed by adopting a low-temperature granulation process. The nutritional value and the utilization rate of the feed can be remarkably improved, and functional components are effectively protected and delivered in a targeted manner, so that the growth and development of the meat gamecocks are promoted, the immune function and the oxidation resistance of the meat gamecocks are enhanced, the meat quality is improved, and the overall health level is improved.

The invention provides a method for extracting polyphenol from persimmon peel and application, the method comprises the steps of persimmon peel pretreatment, irradiation treatment, subcritical ethanol extraction and extraction of polyphenol in different forms, and the method belongs to the technical field of natural product extraction methods. According to the method, electron beam irradiation is utilized to treat persimmon peels, high energy in electron beams can bombard components such as cellulose and lignin in cell walls of the persimmon peels, tightly-combined chemical bonds are broken, ethanol in a subcritical extraction technology can permeate into the persimmon peels to extract polyphenol substances, and therefore the extraction efficiency of polyphenol is improved; and the consumption of the solvent in the extraction process can be reduced. Different forms of polyphenols are further extracted on the basis of the persimmon peel polyphenol crude extract, the polyphenol has good antioxidant capacity and alpha-glucosidase inhibitory activity, bioactive compounds in persimmon peel can be efficiently recycled, and future waste utilization and development of natural antioxidants are promoted.

The invention provides a stem cell culture medium and a preparation method and application of a stem cell exosome with oxidation resistance. The stem cell culture medium comprises baicalin, quercetin, liquiritin and catechin. According to the stem cell culture medium provided by the invention, a mixture of baicalin, quercetin, liquiritin and catechin is adopted as a component of the culture medium to stimulate the stem cells, and the oxidative stress state of the stem cells is changed, so that the stem cells can secrete exosomes with an antioxidant effect, and the secreted exosomes have higher antioxidant capacity. The corresponding stem cell exosome is relatively excellent in the aspect of oxidation resistance.

It relates to Centella asiatica-derived exosomes, which is useful in the treatment and / or care of skin. In particular, Centella asiatica-derived exosomes is effective in enhancing skin whitening, reducing skin wrinkles, enhancing skin hydration, and improving skin antioxidant capacity.

The invention discloses arthrobacter gandavensis N-15 with high selenium resistance and application of the arthrobacter gandavensis N-15, the arthrobacter gandavensis N-15 with high selenium resistance is preserved in the China Center for Type Culture Collection, the preservation number is CCTCC NO: M20242146, and the preservation date is October 9, 2024. The arthrobacter gandavensis N-15 has the advantages that the arthrobacter gandavensis N-15 can be used for preparing the selenium-resistant arthrobacter gandavensis N-15; the selenium resistance of the arthrobacter dabarangensis N-15 reaches 128 mmol / L, and the arthrobacter dabarangensis N-15 has stable adaptability to high selenium concentration and is convenient for biological preparation of nano-selenium. The arthrobacter dawlini N-15 can be used for reducing sodium selenite to generate nano-selenium, and the generated nano-selenium has certain ABTS free radical scavenging capacity and DPPH free radical scavenging capacity, that is, the nano-selenium has relatively good antioxidant capacity. The arthrobacter dawlini N-15 and the nano-selenium produced by the arthrobacter dawlini N-15 can be widely applied to the fields of medicine, food and agriculture.

The invention provides zero-fat low-sugar yoghourt and a preparation method thereof, the zero-fat low-sugar yoghourt comprises the following raw materials: skimmed milk, a fermentation inoculant, a sweetening agent and a protein product, the fat content of the skimmed milk is less than or equal to 0.3 g / 100mL, the protein content of the skimmed milk is greater than or equal to 6.0 g / 100mL, and the lactose content of the skimmed milk is less than or equal to 4.0 g / 100mL; the fermentation inoculant is composed of pichia kudriavzevii, lactobacillus helveticus and streptococcus thermophilus, and the ratio of the three strains is 2: 1: 5. According to the zero-fat low-sugar yoghourt disclosed by the invention, through selection of specific strains, good stability can be realized under the condition that a thickening agent and a stabilizing agent are not added, the product can be endowed with better oxidation resistance, human body metabolism improving efficacy and immunity regulating efficacy, and a green, clean and healthy yoghourt product is really obtained.

The invention relates to a varied massinia, and in particular relates to a separated varied massinia P2-4 with broad-spectrum phagocytosis activity on pathogenic bacteria, and the varied massinia P2-4 is used for phagocytosis in a bacterium cracking manner, so that the activity of the varied massinia P2-4 is improved. The compound has phagocytosis activity on pathogenic bacteria such as pseudomonas aeruginosa, shewanella alginosa, aeromonas cainea, aeromonas hydrophila and photobacterium damsela; the Marsinia variabilis P2-4 provided by the invention can be applied to inhibition of pathogenic bacteria in an aquaculture water body; by adding the varied maleinia sp. P2-4 or the microbial inoculum thereof into the aquaculture feed, the immunity and / or the oxidation resistance and / or the disease infection resistance of the organism of aquaculture animals can be enhanced; the varied marssonia sp. P2-4 disclosed by the invention can be used as a feed additive for aquaculture or a biocontrol product for aquaculture, and can also be used for preventing and / or treating diseases of aquaculture animals.

The invention discloses a chitosan-casein peptide nano-particle and a preparation method and application thereof, and belongs to the technical field of food manufacturing, chitosan and casein peptide are combined into a nano-composite with the particle size of 10-1000 nm through electrostatic interaction in a non-covalent binding mode, and the nano-composite is used for preparing the chitosan-casein peptide nano-particle. A more stable oil-in-water emulsion can be prepared by utilizing the nano composite; the invention also provides a preparation method and application of the chitosan-casein peptide nanocomposite, and a preparation method of the oil-in-water emulsion. The nano-composite prepared by the invention has relatively strong oxidation resistance, foamability and foaming stability when the ratio of chitosan to casein peptide is 1: 1, and an oil-in-water emulsion prepared from the nano-composite has good storage stability, pH stability and ion stability. The preparation method of the nanocomposite is simple and low in cost, and has a good application prospect.

The invention discloses a metagen prepared from bifidobacterium adolescentis and used for promoting synthesis of host collagen, and belongs to the technical field of microorganisms and medicines. The metagen of the bifidobacterium adolescentis CCFM1386 provided by the invention has a good effect of promoting synthesis of host collagen, improves moisture and elasticity of skin, and meanwhile, can improve the antioxidant capacity of the skin and maintain the stable state of collagen. The method specifically comprises the following steps: promoting the enzyme activity of the HSF cell LH1 in vitro by a thallus lysate, and improving the content of COL I and COL III and the enzyme activity of the LH1 in vitro from a fermented supernatant; the bifidobacterium adolescentis has the advantages that the content of collagen is increased by orally taking inactivated thalli, the enzyme activity of LH1, P4H and LOX can be improved by orally taking self-fermentation supernate, the synthesis of the collagen is promoted, and the content of the collagen is increased, so that the bifidobacterium adolescentis has huge application prospects in preparation of oral medicines for promoting the synthesis of host collagen and preparation of foods, health-care products or cosmetics.

The invention belongs to the technical field of microbial fermentation, and discloses lactobacillus mucilaginosus and application thereof in preparation of a uric acid reducing preparation. The survival rate of the fermented lactobacillus mucus in simulated gastric juice with the pH value of 2.0 for 3 hours is greater than 92%, the survival rate in simulated intestinal juice environment containing 0.5% of cholate is greater than 86%, and the viability of the fermented lactobacillus mucus is obviously higher than that of a conventional strain; and the tea has the effects of reducing uric acid, resisting oxidation and inhibiting pathogenic bacteria. The xanthine oxidase inhibition rate of the natural medicinal and edible compound potion obtained by mixing and co-fermenting the strain and existing bacterial powder is greater than 77% (45% or more higher than that of an unfermented group), and the oxidation resistance after fermentation can be improved by 50% at the same time. The beverage is suitable for being drunk as a daily functional food for a long time, and provides a natural and healthy collaborative diet relieving scheme for patients with hyperuricemia and gout.