The invention belongs to the field of medicine, and particularly relates to a method for screening and quantifying ABTS<+>-CE-DAD of antioxidant active components in traditional Chinese medicine. Taking Shuxuening as an example, specific to the aim of verifying the feasibility of the method, nine types of antioxidant active components in Shuxuening are screened and determined. In an experimental process, reaction conditions such as the pH value and phosphate concentration of a buffer solution, the concentrations of sodium dodecyl sulfate and beta-cyclodextrin, the content of acetonitrile, the temperature and the voltage are optimized. Under the same condition, ABTS+ and a Shuxuening injection sample are sampled in sequence, and components with antioxidant activity are reacted with ABTS+ and detected separately. Meanwhile, the certain detected antioxidant active components can be quantified by the determined conditions, and the total content of the active components in a sample is found to be linear with total antioxidant activity. As proved by the result of methodology, the method can be used for screening active compounds in traditional Chinese medicine on line, is easy, convenient, reliable, low in energy consumption, environmentally friendly, and easy for automation.