The invention relates to the technical field of
ion characterization and preparation, in particular to a high-
throughput preparation
mass spectrum device and method giving consideration to high-resolution characterization. The device comprises an
ion source, an
ion transmission cavity, a
quadrupole mass screening cavity, an
ion dissociation cavity, an ion deflection cavity, an ion deceleration and deposition cavity and a high-resolution
mass spectrum characterization cavity which are sequentially arranged, wherein the high-resolution
mass spectrum characterization cavity is formed in one side of the ion deflection cavity in the vertical direction; soft
ionization is combined with a
quadrupole analyzer to screen ions, the ions are dissociated through a dissociation cavity, an ion deflection cavity is used for selecting a high-resolution characterization or high-
throughput preparation function, a high-resolution
mass spectrum characterization cavity is used for achieving high-resolution characterization of screened and fragmented ions, and an ion deceleration and deposition cavity is used for high-
throughput preparation of the ions. According to the method, perfect compatibility of high-throughput preparation and high-resolution
mass spectrum characterization is realized through ion deflection design, and the method has a wide application prospect in the fields of efficient preparation of biological macromolecules, synthetic macromolecules and the like and the like.