484 results about "Respiration" patented technology

A system and method for providing a therapeutic treatment, such as a flow of breathing gas, to a patient at variable treatment levels. A respiratory cycle monitor detects the patient's respiratory cycles and a control unit incrementally adjusts the treatment level from a first predetermined level to a second predetermined level over a first predetermined number of respiratory cycles. The amount of the incremental adjustment and the frequency of such adjustments over the course of the first predetermined number of respiratory cycles can be controlled to achieve a desired change in the therapeutic treatment over the course of the patient's respiration.

A pharmaceutical composition and formulations comprise preventative, prophylactic or therapeutic amounts of an oligo(s) anti-sense to a specific gene(s) or its corresponding mRNA(s), and a glucocorticoid and / or non-glucocorticoid steroid or a ubiquinone or their salts. The agents, composition and formulations are used for treatment of ailments associated with impaired respiration, bronchoconstriction, lung allergy(ies) or inflammation, and abnormal levels of adenosine, adenosine receptors, sensitivity to adenosine, lung surfactant and ubiquinone, such as pulmonary fibrosis, vasoconstriction, inflammation, allergies, allergic rhinitis, asthma, impeded respiration, lung pain, cystic fibrosis, bronchoconstriction, COPD, RDS, ARDS, cancer, and others. The present treatment is effectively administered by itself for conditions without known therapies, as a substitute for therapies exhibiting undesirable side effects, or in combination with other treatments, e.g. before, during and after other respiratory system therapies, radiation, chemotherapy, antibody therapy and surgery, among others. Each of the agents of this invention may be administered directly into the respiratory system so that they gain direct access to the lungs, or by other effective routes of administration. A kit comprises a delivery device, the agents and instructions for its use.

Method and apparatus for determining the state of entrainment between biological systems which exhibit oscillatory behavior such as heart rhythms, respiration, blood pressure waves and low frequency brain waves based on a determination of heart rate variability (HRV) and an evaluation of the power spectrum thereof. Entrainment reflects a harmonious balance between the two branches of the autonomic nervous system within the body. This internal state of heightened physiological efficiency enhances health and promotes optimal performance. According to one embodiment a method is used to determine the entrainment level based on an entrainment parameter related to HRV. The method first determines the power distribution spectrum (PSD) and then calculates an entrainment parameter (EP), which is a measure of the power distribution in the HRV spectrum. High EP values occur when this power is concentrated within a relatively narrow range of frequencies, and lower values when the power is distributed over a broader range of frequencies. In one embodiment, an apparatus is provided for monitoring the heart beat and presenting this information via a personal computer, handheld device, or other processing means.

The invention comprises an X-ray system that is orientated to provide X-ray images of a patient in the same orientation as viewed by a proton therapy beam, is synchronized with patient respiration, is operable on a patient positioned for proton therapy, and does not interfere with a proton beam treatment path. Preferably, the synchronized system is used in conjunction with a negative ion beam source, synchrotron, and / or targeting method apparatus to provide an X-ray timed with patient respiration and performed immediately prior to and / or concurrently with particle beam therapy irradiation to ensure targeted and controlled delivery of energy relative to a patient position resulting in efficient, precise, and / or accurate noninvasive, in-vivo treatment of a solid cancerous tumor with minimization of damage to surrounding healthy tissue in a patient using the proton beam position verification system.

A method and apparatus for treating a breathing disorder and, more particularly, a method and apparatus for providing a pressurized air flow to an airway of a patient to treat congestive heart failure in combination with Cheyne-Stokes respiration and / or sleep apnea or other breathing disorders. A positive airway pressure ventilator is utilized in combination with an algorithm that adjusts IPAP and EPAP in order to counter a Cheyne-Stokes breathing pattern. Cheyne-Stokes respiration is detected by monitoring a peak flow of the patient.

This invention relates generally to treatment of solid cancers. More particularly, the invention relates to a computer controlled patient positioning, immobilization, and repositioning method and apparatus used in conjunction with multi-field charged particle cancer therapy coordinated with patient respiration patterns and further in combination with charged particle beam injection, acceleration, extraction, and / or targeting methods and apparatus.

Methods and apparatus monitor health by detection of sleep stage. For example, a sleep stage monitor (100) may access sensor data signals related to bodily movement and / or respiration movements. At least a portion of the detected signals may be analyzed to calculate respiration variability. The respiration variability may include one or more of variability of respiration rate and variability of respiration amplitude. A processor may then determine a sleep stage based on one or more of respiration variability and bodily movement, such as with a combination of both. The determination of sleep stages may distinguish between deep sleep and other stages of sleep, or may differentiate between deep sleep, light sleep and REM sleep. The bodily movement and respiration movement signals may be derived from one or more sensors, such as non-invasive sensor (e.g., a non-contact radio-frequency motion sensor or a pressure sensitive mattress).

The present invention provides an artificial respiration apparatus 12 of a high oscillation type, in which oxygen supply to a patient P and exhaled gas discharge are urged by an oscillating gas having a higher frequency than the cycle of the patient respiration. The apparatus includes a discharge direction regulating mechanism 7 for regulating the exhaled gas to flow only in the discharge direction.

A method of targeting therapy such as radiation treatment to a patient includes: identifying a target lesion inside the patient using an image obtained from an imaging modality selected from the group consisting of computed axial tomography, magnetic resonance tomography, positron emission tomography, and ultrasound; identifying an anatomical feature inside the patient on a static ultrasound image; registering the image of the target lesion with the static ultrasound image; and tracking movement of the anatomical feature during respiration in real time using ultrasound so that therapy delivery to the target lesion is triggered based on (1) movement of the anatomical feature and (2) the registered images.

The present invention relates to a determination method for making it possible to determine the position of a body part subject to vital movement that is to be irradiated, by means of determining a region of an analytical image,wherein the region represents a body part subject to vital movement, in particular a tumor in an anatomical body, and performs a change in position from one analytical image to the next that reflects the vital movement, wherein the body parts subject to vital movement are parts of the body that are to be irradiated or are not to be irradiated and that move as a result of vital functions such as respiration and / or heartbeat even when the anatomical body is otherwise kept deliberately at rest,advance analytical image data, which includes the description of an advance analytical image having an advance region in which a first body part subject to vital movement is represented, is provided,procedure analytical image data that includes the description of a procedure analytical image of the body structure is provided,on the basis of the advance analytical image data and the procedure analytical image data, a procedure region, which corresponds to the advance region and occupies a procedure position in the procedure analytical image, is determined in the procedure analytical image,wherein a) determination of the procedure position of the procedure region is based on movement data that includes information on the vital movements of the body parts that are caused by the vital functions, and / or b) determination of the position of a second body part subject to vital movement is based on the determined procedure position and information on the relative position between the first and the second body part subject to vital movement.

The invention relates generally to treatment of solid cancers. More particularly, the invention relates to enhancing synchrotron acceleration cycle usage efficiency by adjusting the synchrotron's acceleration cycle to correlate with a patient's respiration rate where efficiency refers to the duty cycle or the percentage of acceleration cycles used to deliver charged particles to the tumor. The system senses patient respiration and controls timing of negative ion beam formation, injection of charged particles into a synchrotron, acceleration of the charged particles, and extraction to yield delivery of the particles to the tumor at a predetermine period of the patient's respiration cycle. Independent control of charged particle energy and intensity is maintained during the timed irradiation therapy. Multi-field irradiation ensures efficient delivery of Bragg peak energy to the tumor while spreading ingress energy about the tumor.

A system and method for delivering a flow of breathing gas to an airway of a patient. A characteristic that varies based on variations of the flow of the breathing gas is monitored and used to determine a Target Flow for the gas delivered to the patient. The Target Flow is set to a level sufficient to treat Cheyne-Stokes respiration or a sleep disordered breathing event. The Target Flow is altered if the patient experiences a sleep disordered breathing event. In a further embodiment, the system determines an apnea detection time (Tapnea) as Tinsp plus a constant, and delivers a machine triggered breath if an amount since the start of inspiration reaches Tapnea. Yet another embodiment monitors the characteristic during an inspiratory phase of a respiratory cycle, and controls the flow of gas during the inspiratory phase of the respiratory cycle based on a result of this comparison.

Patient respiration may be characterized using a marked respiration waveform involving a respiration waveform annotated with symbols, markers or other indicators representing one or more respiration characteristics. A respiration waveform may be acquired by sensing a physiological parameter modulated by respiration. A marked respiration waveform may be generated based on the acquired respiration waveform and one or more detected respiration waveform characteristics and / or respiration-related conditions. One or more components used to generate the marked respiratory waveform may be fully or partially implantable.

Method for providing ventilatory settings with regard to the airway pressure levels of an artificial ventilator, the artificial ventilator is connected to a lung, including the steps of obtaining data samples of a gas concentration of the expired gas over a single breath; selecting a plurality of data samples from the obtained data samples; calculating a tracing value being sensitive to changes of alveolar dead space on the basis of the selected data samples; repeating steps a), b) and c) for obtaining a plurality of tracing values; and changing at least one airway pressure level of the artificial ventilator, wherein from an observation of a resulting course of the plurality of calculated tracing values an airway pressure level at which alveolar opening or lung overdistension or lung open condition or alveolar closing occurs is detected. Apparatus for providing ventilatory settings with regard to the airway pressure levels of an artificial ventilator is also disclosed.

This invention relates to a system and a kit for stress and relaxation management. A cardiac activity sensor (101) is used for measuring the heart rate variability (HRV) signal of the user and a respiration sensor (102) for measuring the respiratory signal of the user. The system contains a user interaction device (103) having an input unit (104) for receiving user specific data and an output unit for providing information output to the user. A processor (106) is used to assess the stress level of the user by determining a user related stress index. The processor is also used to monitor the user during a relaxation exercise by means of determining a relaxation index based on the measured HRV and respiratory signals, the relaxation index being continuously adapted to the incoming measured signals and based thereon the processor instructs the output unit to provide the user with biofeedback and support messages. Finally, the processor uses the user specific data as an input in generating a first set of rules defining an improvement plan for self-management of stress and relaxation. The first set of rules is adapted to trigger commands instructing the output unit to provide the user with motivation related messages. Also, at least a portion of said user specific data is further used to define a second set of rules indicating the user's personal goals.

The invention concerns an apparatus for supplying a respiratory gas, a humidifying apparatus, a respiratory gas tube and a connecting apparatus therefor. The apparatus of the invention includes a blowing device for delivering the respiratory gas, a housing device which has a bottom region, a top surface region and a side region extending upwardly between the top surface region and the cover region, as well as a connecting device for connecting a humidifying apparatus for humidifying the respiratory gas, wherein the connecting device is arranged in the side region of the apparatus in such a way that the humidifying apparatus can be laterally coupled thereto. The humidifying apparatus according to the invention is distinguished by a partial amount discharge device for passing a partial amount of the liquid pre-stored in a liquid storage space into a humidifying region. The respiration tube according to the invention includes a connecting plug structure which has both a respiratory gas connecting portion and also a pressure measuring tube connecting portion.

The present invention provides a static human body heartbeat and respiration signal extraction method based on an FMCW radar. Firstly, obtaining three parameter information of distance, Doppler and angles of a human body target according to analysis and calculation of human body target detection data, then constructing three parameter images of a distance-time image, a distance-Doppler image and adistance-angle image, then using the images to determine the human body target to be detected through a target individual existing in a 2D-OS-CFAR detection environment and at the same time suppresshuman body target signal's interference to the human body target signals to be detected, and finally conducting heartbeat and respiratory signal extraction on the detected human body target to be detected based on an extended DACM algorithm of derivation operation. The static human body heartbeat and respiration signal simple extraction method based on the FMCW radar is innovatively provided, realizes non-contact type detection of the human body heartbeat and respiratory signals, avoids constraint and discomfort of patients caused by traditional contact detection devices, at the same time caneffectively inhibit interference and separates the human body target signals to be detected.

Systems and methods provide for determining blood gas saturation based on one or more measured respiration parameters. A parameter of respiration is measured implantably over a duration of time. The measured respiratory parameter is associated with a blood gas saturation level. Blood gas saturation is determined based on the measured respiration parameter. At least one of associating the measured respiratory parameter and determining blood gas saturation is preferably preformed implantably.

An improved sensor (102) for respiratory and metabolic monitoring in mobile devices, wearables, security, illumination, photography, and other devices and systems uses an optional phosphor-coated broadband white LED (103) to produce broadband light (114), which is then transmitted along with any ambient light to a target (125) such as the ear, face, or wrist of a living subject. Some of the scattered light returning from the target to detector (141) is passed through narrowband spectral filter set (155) to produce multiple detector regions, each sensitive to a different waveband wavelength range, and the detected light is spectrally analyzed to determine a measure of respiration of the subject, such as respiratory rate, volume, effort, depth, or respiratory variability. In one example, variations in components of the bloodstream over time such as hemoglobin and water are determined based on the detected light, and said measure of respiration is then determined based on the in components of the bloodstream over time, with venous compartment changes as a result of body movement and body position changes, and skin surface compartment changes as a result of sensor movement, substantially removed. In the absence of the LED light, the ambient light may be sufficient illumination for analysis. The same sensor can provide identifying features of type or status of a tissue target, such as heart rate or variability, hydration status, or even confirmation that the tissue is alive. Respiratory monitoring systems incorporating the sensor, as well as methods, are also disclosed.

Disclosed herein is a new and improved non-invasive bed sensing system for detecting and monitoring physiological movements such as heartbeat and respiration. The system may employ a hydraulic fluid to transduce the physiological pressures to an integrated pressure sensor and a new and improved signal processing method to identify individual cardiac pulses from the electronic signals generated by the hydraulic transducer. The system provides increased sensitivity capable of capturing quantitative pulse and respiration rates with subtle changes, ability to distinguish between instances of low pulse rate and shallow breathing, and improved comfort over existing system.

The invention relates generally to treatment of solid cancers. More particularly, the invention relates to a multi-field charged particle cancer therapy method and apparatus coordinated with negative ion beam creation, ion beam focusing, charged particle acceleration, patient rotation, and / or patient respiration. Preferably, the charged particle therapy is performed on a patient in a partially immobilized and repositionable position. Proton delivery is preferably timed to patient respiration via control of charged particle beam injection, acceleration, and / or targeting methods and apparatus.

A method and apparatus of tracking a change in a region of interest in an subject according to respiration are provided. For example, an apparatus embodiment may include a model selector configured to select a model from among models of a region of interest of an subject generated to indicate a change in a region of interest during a respiration cycle of the subject, a respiration signal obtainer configured to obtaining a respiration signal of the region of interest by using ultrasound images including the region of interest obtained during the respiration cycle of the subject, and an information obtainer configured to obtain information regarding the region of interest at a time when the ultrasound images are obtained, from the selected model, by using the obtained respiration signal.

The invention discloses a strain of yeast with strong capacities of tolerating, enriching and converting organic selenium, which is named Candida utilis CUM and has been preserved in China center for type culturecollection on April 19, 2010 with the preservation number of CCTCC M 2010090. The Candida utilis CUM has the bacterial characteristics that: cells are round, oval or sausage-shaped, and performs vegetative propagation in a mode of multi-edge germination to form pseudohypha; wort solid culture is carried out, and the bacterial colony is milk white, has smooth and moist surface, gloss or no gloss, and neat or hypha-shaped edges; the Candida utilis CUM is chemoheterotrophic, and can ferment glucose, cane sugar and raffinose; and the Candida utilis CUM is facultatively anaerobic, performs aerobic respiration under the aerobic conditions and performs alcoholic fermentation under the anaerobic conditions. The Candida utilis has strong selenium enriching capacity and good stability, can be used for producing selenious yeast, and is a strain with high research and development value.

What is disclosed is a system and method for processing a video for respiratory function analysis. In one embodiment, a video is received of a region of the subject's body where a time-varying signal corresponding to the subject's respiration can be registered by the video camera. Pixels in a first batch of frames are processed to obtain a time-series signal which is filtered using a band-pass filter with a low and high cutoff frequency fL and fH, where fL and fH are a function of the subject's tidal breathing. The filtered time-series signal is analyzed to identify a next low and high cutoff frequency f′L and F′H, where fL<f′L and f′H<fH. Thereafter, next successive batch of frames are repeatedly processed to obtain respective next time-series signal which is filtered using a band-pass filter with the cutoff frequency f′L and f′H. The filtered signals are processed to obtain a respiratory signal.

The invention relates to a breath sampling instrument and the method for sampling breath, belonging to technical field of medical installation. The breath sampling instrument comprises a probe tube which is provided with a gas port and an air outlet. A mouth is arranged on the gas port of the probe tube and a first check valve and a second check valve are arranged in the airflow channel between the gas port and the air outlet. A test sample disconnecting and intercepting device is arranged between the first check valve and the second check valve. By using the breath sampling instrument, the airflow blown out can open the first check valve and then enter the airflow channel when the tester keeps the instrument in mouth to blow or cough, and the test sample disconnecting and intercepting device can separate and keep the fluid phase or the solid phase of the airflow blown out. The gas phase separated opens the second check valve before discharging and then the test sample disconnecting and intercepting device is put out for laboratory test. The invention can not harm or upset the tester and also has the advantages of simple structure and convenient usage, so can be used in quick diagnosis of different diseases.