100 results about "Blood volume" patented technology

Blood separation methods and systems are provided for mid-processing calculation of blood composition. Blood is conveyed into a device having an outlet line and the device is spun to separate a blood component from the blood. A flow of blood component is conveyed from the device by the outlet line and the blood component in the outlet line is optically measured. With said optical measurement, a current blood component yield, a blood component pre-count, the volume of blood to process to collect a target amount of said blood component, and/or the processing time required to collect a target amount of said blood component is calculated. The optical measurement can also be used to calculate an amount of storage fluid to convey into a collection container with the blood component.

The present invention provides a method of measuring a component in blood, by which the amounts of blood cells and an interfering substance can be measured with high accuracy and high reliability and the amount of the component can be corrected accurately based on the amounts of the blood cells and the interfering substance. In a sensor for measuring a blood component, a first working electrode 13 measures a current that flows during a redox reaction of a blood component, a second working electrode 17 measures the amount of blood cells, and a third working electrode 12 measures the amount of an interfering substance. Next, based on the measurement results, the amount of the blood component to be measured is corrected. Thus, more accurate and precise measurement of the amount of the blood component can be realized.

An apparatus and method is provided that provide, in real-time, an accurate detection and warning of dangerous blood or fluid loss to warn of impending hypovolemia, by non-invasive monitoring and processing of photoplethysmography data.

A device used to treat heart disease by decreasing the size of a diseased heart, or to prevent further enlargement of a diseased heart. The device works by limiting the volume of blood entering the heart during each cardiac cycle. The device partitions blood within the heart, and protects the heart from excessive volume and pressure of blood. The device is placed within the interior of the heart, particularly within a ventricular cavity. The device is a hollow sac, with two openings, which simulates the shape and size of the interior lining of a ventricle of a normal heart. It allows the ventricle to fill through one opening juxtaposed to the annulus of the inflow valve to a predetermined, normal volume, and limits filling of the heart beyond that volume. It then allows blood to be easily ejected through the second opening through the outflow valve. By limiting the amount of blood entering the ventricle, the ventricle is not subjected to the harmful effect of excessive volume and pressure of blood during diastole, the period of the cardiac cycle when the heart is at rest. This allows the heart to decrease in size, or to reverse remodel, and to recover lost function. In some applications, a second device may be simultaneously placed inside the heart to take up excessive space between the heart and the primary device.

Aspects of the invention relates to systems and methods for hypovolemia and/or hypervolemia detection of a living subject using peripheral intravenous waveform analysis. In one embodiment, the method includes: acquiring, from a vein of the living subject, peripheral venous signals; performing a spectral analysis on the acquired peripheral venous signals to obtain a peripheral venous pressure frequency spectrum; and performing a statistical analysis on amplitudes of peaks of the peripheral venous pressure frequency spectrum to determine the blood volume status of the living subject in real time. Specifically, at least two peaks, respectively corresponding to a first frequency and a second frequency, are obtained on the peripheral venous pressure frequency spectrum. Amplitude change of the second peak is used to determine the blood volume status of the living subject. Hemorrhage may be detected when a significant amplitude decrease is detected from the second baseline peak to the second peak.

Novel devices which can be used to both collect blood samples from and administer medical fluids to a patient on a repeated and continual basis using one rather than multiple needle insertions. The devices are capable of removing blood from one of the patient's veins using the intrinsic venous pressure of the blood and capillary action of the device, thereby preventing vacuum-induced collapse of the vein. The device typically includes a main tubing segment confluently connected to a cannula for insertion in the patient's vein. A syringe port and a volumeter for collecting blood branch separately from the main tubing segment. The device is used to collect blood by attaching an empty blood collection syringe to the syringe port, inserting the cannula in the patient's vein, allowing passive flow of blood from the main tubing segment into the volumeter under intrinsic venous blood pressure and capillary action, and then facilitating active flow of blood from the volumeter into the blood collection syringe by extending the syringe plunger. The blood-filled syringe may be replaced by additional empty blood collection syringes and the procedure repeated, as needed, depending on the quantity of blood to be obtained. The device may be used to administer medical fluids to the patient by first removing the residual blood from the main tubing segment and volumeter, flushing the main tubing segment with sterile normal saline and administering the fluids to the patient through the main tubing segment from a medical fluid syringe or catheter attached to the syringe port.

The abdominal circulatory pump uses expulsive manoeuvres performed by contraction of the diaphragm while stabilizing, contracting or compressing the abdominal wall to increase abdominal pressure and pump blood. At the same time, it can be used to lower pleural pressure around the surface of the lung to provide ventilation. In humans the blood in the splanchnic circulation; i.e., the blood in the abdominal contents, is a reservoir of about 20% to 25% of the whole body blood volume. The increase in abdominal pressure forces this blood to flow out of the abdomen and through the body.

A method and system for accurately measuring a very small volume of blood is used for accurate evaluation of an amount (volume) of blood collected by a lancing device, evaluation of a scientific very small amount of blood, and so on. The method includes the steps of collecting the very small volume of blood, absorbing the very small volume of collected blood into an absorption medium, drying the absorption medium, scanning the dried absorption medium using an image scanner connected to a computer to obtain a digital image, and calculating the very small volume of blood from the digital image using an analysis program.

An apparatus for detecting and notifying occurrence of post-partum haemorrhage in female patients is envisaged. Continued tracking of the blood discharged from a female patient's body during labor as well as postnatal operation procedures is provided for, and as soon as the amount of blood discharged from the body of the female patient exceeds a predetermined threshold value, a light-based alarm and sound-based alarm are triggered. The apparatus includes a first connector connected to the female patient when she is on a Labor Recovery Delivery bed, and a second connector woven onto an undergarment to be worn by the female patient. The first connector and second connector are connected to single use, disposable blood collection bags, whose weights are measured using weight sensors for an accurate calculation of the total amount of the blood lost by the female patient during labor operation procedures and postnatal operation procedures.

Highly hydrophilic indole and benzoindole derivatives that absorb and fluoresce in the visible region of light are disclosed. These compounds are useful for physiological and organ function monitoring. Particularly, the molecules of the invention are useful for optical diagnosis of renal and cardiac diseases and for estimation of blood volume in vivo.

Ruptured Abdominal Aortic Aneurysms (AAA) cause a large number of deaths annually. Ruptures occur even in people who are already diagnosed with AAA and are being monitored. The reason is that the interval between tests is too long because of the need to visit a pathological facility with imaging equipment. It is preferable to estimate the progress of AAA frequently, once detected, in a non-invasive manner, preferably at the subject's home, without the need for the subject to visit a pathological facility. A device is disclosed for detecting a state of a vascular pathology of a subject, comprising a sensor signal unit (103) for providing a signal representative of a blood volume in a body part of a subject, a comparator (107) for comparing the sensor signal with a reference signal, and a user interface (109) for conveying a result based on the comparison to a user of the device.

A method determines cardiac output or stroke volume by receiving signal data representing multiple parameters of a patient concurrently acquired over a particular time period and comprising at least one of, (a) a parameter derived from an ECG waveform of the patient, (b) a parameter derived from a blood pressure signal of the patient, (c) a parameter derived from signal data representing oxygen content of blood of the patient and (d) a parameter derived from a patient cardiac impedance value. A selected parameter of the multiple concurrently acquired parameters is used in calculating a heart stroke volume of the patient comprising volume of blood transferred through the blood vessel in a heart cycle, in response to, a combination of a weighted summation of values of the selected parameter over the particular time period. Data representing the calculated heart stroke volume is provided to a destination device.

An optical vital signs sensor (100) is provided, which comprises a PPG sensor (102), a force transducer (130) configured to measure a force applied via the PPG sensor (102) to a skin (1000) of the user and a processing unit (140) configured to extract information regarding a blood volume pulse from the output of the PPG sensor (102) and to map the extracted information to the blood pressure value at a specific force applied to the PPG sensor (102).

The invention discloses a blood vessel blocker capable of controlling the blood flow volume. The blood vessel blocker comprises a supporting plate and a squeezing plate which are oppositely arranged on the two sides of a blood vessel. The supporting plate is connected with a support spanning the blood vessel, a groove with the central line perpendicular to the squeezing plate is formed in the end, located outside the squeezing plate, on the support, an air bag and a guiding block moving along the central line of the groove are arranged in the groove, the air bag is communicated with an inflating device, and the guiding block is connected with a squeezing plate through a connecting rod. The blood vessel blocker further comprises a pressure sensor used for measuring the pressure of the blood vessel, and a probe of the pressure sensor is arranged on the inner side of the supporting plate or the squeezing plate. By means of the blood vessel blocker, blood flow blocking at any degree can be obtained in operation according to experimental needs, and thus the blood flow blocking situation of blood vessels of different thicknesses and different kinds can be more accurately and more visually measured; meanwhile, the reversible operation of increasing or decreasing of the blood flow volume can be achieved, and convenience is provided for blood flow volume detection related experiments or treatment control.

The invention relates to a terlipressin acetate nasal cavity spray and a preparation method thereof. The spray is composed by terlipressin acetate, absorption enhancer, osmotic pressure regulator, preservative and pH regulator. The preparation method of the spray mainly comprises raw material preparing, dissolving, bottle washing, filling, packing and the like. The spray has the main functions of contracting smooth muscles of visceral vessels and reducing blood flow volume of the viscera, accordingly, the portal vein blood flow and portal vein pressure are reduced, and meanwhile, the spray can be used for the smooth muscles of the esophagus and the uterus. The spray is convenient to dose, has high bioavailability, and is beneficial to patients to accept.

The invention discloses a compound thrombus-clearing Chinese medicinal preparation and a preparation method thereof. The compound thrombus-clearing Chinese medicinal preparation comprises active ingredients and/or pharmaceutically acceptable additives which are prepared from the following raw materials: 200 to 1,000 grams of sanchi, 50 to 400 grams of astragalus, 40 to 20 grams of radix salviae miltiorrhizae, 60 to 400 grams of figwort root, and 100 to 800 grams of sanchi decoction dreg powder. The Chinese medicinal preparation has the functions of quickening the blood and transforming stasis, expanding blood vessels, increasing blood flow volume, improving blood circulation and microcirculation and tonifying qi and yin and is mainly used for treating the symptoms of retinal vein occlusion caused by blood stasis and qi and yin deficiency, such as blurred vision or paropsis, eyeground blood stasis, fatigued spirit and lack of strength, dry throat and dry mouth. The Chinese medicinal preparation is also applicable to people with the symptoms of stable exertional angina caused by blood stasis and qi and yin deficiency, such as chest distress, chest pain, palptation, flusteredness, shortness of breath, lack of strength, heart vexation and dry mouth.