4 results about "Fibrous membrane" patented technology

The application relates to the field of medical devices, in particular to a tracheal cannula end balloon, a preparation method thereof and a tracheal cannula. The tracheal cannula end balloon comprises a balloon body and a double-layer structure arranged on the surface of the balloon body, and the double-layer structure comprises a first nanofiber membrane and a second nanofiber membrane; the first nanofiber membrane comprises a first matrix material and paclitaxel, and the first matrix material comprises polyethylene glycol and polycaprolactone; the second nanofiber membrane comprises a second matrix material and ropivacaine, and the second matrix material comprises polyethylene glycol and polyvinylpyrrolidone. In the application, the double-layer structure design realizes layered release of the drugs, the outer-layer drugs rapidly relieve pain and inflammation, and the inner-layer drugs continuously inhibit cell proliferation, so that the problems caused by the tracheal cannula end balloon are comprehensively solved.

This invention provides an oral repair membrane and its preparation method. The oral repair membrane comprises: a substrate, which is formed by interlocking and winding fibers with a diameter of 10 nm-100 μm and has a porous structure; and active particles, which are loaded on the surface and / or inside the substrate, and the active particles are derived from piezoelectric materials and / or hydrophilic polymer materials. The oral repair membrane of this invention has a porous structure with a suitable pore size, which can better shield fibroblasts from growing into the fibrous membrane, avoiding the problem of membrane thickening caused by fibroblast growth. It also has good softness and adhesion, and will not slip during use, avoiding the risk of membrane exposure and reducing the exposure infection rate.

The application discloses a wet-adhesion nanofiber composite membrane for promoting healing of tooth extraction sockets, a preparation method thereof and application thereof, and comprises the following steps: step one: dissolving a first material in an organic solvent, uniformly mixing to obtain a first solution; step two: dissolving a second material in deionized water and / or an organic solvent, uniformly mixing to obtain a second solution; step three: using an electrospinning technology, electrospinning the first solution in a first syringe to prepare an outer nanofiber membrane; electrospinning the second solution in a second syringe to directly form an inner nanofiber membrane on the surface of the outer nanofiber membrane, and obtain the wet-adhesion nanofiber composite membrane; wherein the first material at least comprises any one of thermoplastic polyurethane and polyacrylonitrile; the second material at least comprises polyacrylic acid; the voltage used in the electrospinning is 10kV-25kV, the receiving distance is 10cm-20cm, and the sample injection rate is 0.3mL / h-1.5mL / h. The wet-adhesion nanofiber composite membrane can promote rapid reformation of gingival epithelium and maintain stable morphology of alveolar ridges through guided bone integration.