824 results about "Membrane layer" patented technology

The invention provides a secondary battery and an electric device, and relates to the field of batteries. The secondary battery comprises a positive pole piece, a negative pole piece and an isolating membrane, the positive pole piece comprises a positive current collector and a positive membrane layer arranged on at least one side surface of the positive current collector, and the compaction density of the positive membrane layer is 2.0-3.0 g / cm < 3 >; the negative pole piece comprises a negative current collector and a negative film layer located on at least one surface of the negative current collector, and the compaction density of the negative film layer is 1.4 g / cm < 3 >-1.85 g / cm < 3 >; the isolating membrane comprises a base membrane, the thickness of the base membrane ranges from 4 micrometers to 12 micrometers, the base membrane is provided with nanopores, and the average pore size of the nanopores ranges from 10 nm to 300 nm. The secondary battery has high energy density and improved safety performance.

A working wire for a biological sensor is disclosed. The working wire includes a substrate comprising cobalt-chromium (Co—Cr) alloy or Nitinol alloy, a platinum layer comprising platinum on the substrate, and a membrane layer comprising a biological membrane applied over the platinum layer.

A pervaporation composite membrane belongs to the technical field of membrane separation. The pervaporation composite membrane comprises a porous substrate, a middle membrane layer and a separation membrane layer which are sequentially stacked, the average pore size of the porous substrate is greater than or equal to 250nm; the average pore size and porosity of the middle film layer are smaller than those of the porous substrate, and the middle film layer has the organic matter affinity characteristic; the separation membrane layer has the hydrophobic characteristic and the organic matter selective permeation characteristic. The middle membrane layer is beneficial to improving the problems of seepage holes, difficulty in spreading, uncontrollable thickness of the separation membrane layer and the like in the solid-liquid interface preparation process, ensures the defect-free preparation of the separation membrane layer, and is beneficial to improving the permeability of the pervaporation composite membrane to organic matters.

The present application relates to a hybrid membrane for an electrochemical device, the hybrid membrane comprising: a membrane layer comprising: a modified metal-organic framework (MOF) material wherein the modified MOF material is a MOF material modified with one or more of a lithium salt, a carboxylic acid, or an amino acid, and a binder material, the adhesive layer is used for adhering the modified MOF material to the porous supporting layer so as to form a film layer on the porous supporting layer; and the porous support layer is used for providing mechanical support for the membrane layer. The present application also relates to a method for preparing the hybrid membrane, an electrochemical device comprising the hybrid membrane and the use of the hybrid membrane for inhibiting Lewis acid by-products in an electrochemical device.

The invention discloses a Fe / C loaded membrane module, a PN / A-MABR autotrophic nitrogen removal device, a preparation method and a sewage treatment method, and belongs to the technical field of sewage treatment. According to the invention, the problem that the treatment effect is influenced by NO3 <->-N accumulation in the existing membrane aeration coupling partial nitrification-anaerobic ammonia oxidation process is solved. Comprising a frame and a membrane body attached to the outer portion of the frame, the membrane body comprises a hydrophobic organic membrane layer, an iron-carbon material layer and a biological membrane layer which are sequentially arranged, and the hydrophobic organic membrane layer is attached to the outer portion of the frame. The iron-carbon material is added between the hydrophobic organic membrane layer and the biological membrane layer, the iron-carbon micro-electrolysis process is coupled with the dissimilatory process of nitrate generated by microbial metabolism, the removal of NO3 <->-N generated by anaerobic ammonia oxidation is enhanced, and the total nitrogen removal efficiency is improved.

The present invention belongs to the field of plating technology and specifically relates to an ALD-Parylene composite film layer, a deposition device, and a deposition method thereof. By reserving a vacuum gap between a heating plate and the outer wall of a cavity, a barrier is formed to isolate the heating plate from heat conduction to the outside of the cavity as the vacuum degree in the cavity increases during the reaction process, thereby avoiding heat loss caused by direct contact and damage to seals, thereby improving the coating effect. The ALD reaction and the Parylene reaction are combined in the same reaction chamber, and different pipeline designs and time-sharing control are used to form a composite film layer structure of alternating ALD film layers and Parylene film layers on the surface of the substrate. The density of the ALD film layer is conducive to enhancing the water resistance of the film layer and sealing the defects of the original Parylene film layer. The softness of the original coating is maintained, and it will not break when subjected to impact and thermal shock, which is conducive to improving the stability of the film layer.

To provide an analysis element and a manufacturing method thereof that can prevent an object to be analyzed from being unable to be analyzed appropriately.SOLUTION: A manufacturing method of this analysis element 100 includes the steps of forming a mask layer 20, forming a membrane layer 30, exposing a substrate 10, forming an introduction hole 13 and forming a protrusion 14 at the inlet end 13a of the introduction hole 13, and removing the protrusion 14 by wet etching the protrusion 14.SELECTED DRAWING: Figure 13

The invention discloses a green construction of a porous separation membrane and an efficient uranium separation / enrichment method thereof.The method comprises the steps that firstly, mixed-dimension attapulgite clay acid etching powder is modified through phytic acid and then added into a saponin plant extracting solution, and then the mixture is mixed with a sodium alginate-chitosan double-network matrix; a film-forming solution with a high-mechanical-stability gas-liquid interface is obtained through a Pickering foam template method, and then the porous separation film is controllably constructed through cooperative strategies such as film casting, calcium cross-linking and carboxylation. Based on the advantages of a rod / sheet mixed dimension structure of minerals, synergistic interaction of plant derivatives and a spatial orientation regulation and control synergistic mechanism of functional groups, a porous separation membrane with a specific porous structure, excellent mechanical properties and uranium separation efficiency is constructed in a green manner, and the uranium separation efficiency is improved by combining optimization of membrane layer stacking and elution strategies. A high-efficiency uranium separation / enrichment method is developed, and a new normal form is provided for solving uranium pollution prevention and control and resource recovery and enrichment by a membrane separation technology.

The invention discloses a double-layer piezoelectric sensor and an application and method of the double-layer piezoelectric sensor in representing beta-phase polyvinylidene fluoride membrane adsorptive pollution, a piezoelectric beta-phase polyvinylidene fluoride membrane is a porous membrane formed by a blending system of polyvinylidene fluoride and ionic liquid and has a beta-phase crystal structure and a piezoelectric response characteristic, and the piezoelectric beta-phase polyvinylidene fluoride membrane is prepared by spin-coating a PVDF solution on a chip. The double-layer piezoelectric sensor containing the beta-phase polyvinylidene fluoride membrane is obtained, and QCM-D detection is carried out to characterize the adsorptive pollution condition of the beta-phase polyvinylidene fluoride membrane. Adsorption and desorption behaviors of organic matters with different dissolvability and mixtures thereof on the beta-phase PVDF membrane layer are represented, the adsorption result is matched with the hole blocking resistance in the actual membrane pollution process, and the hole blocking resistance is calculated by monitoring the fifth overtone of the piezoelectric quartz sensor. And the quality of soluble organic matters adsorbed on the PVDF surface and the property of an adsorption layer can be evaluated by using a frequency change value and a dissipation value, and a scheme is provided for researching the pollution behavior of the beta-phase polyvinylidene fluoride membrane.

The present invention relates to a composite separator for a lithium metal battery, a preparation method for a composite separator, and a lithium metal battery. The composite separator for a lithium metal battery comprises a separator layer and an NF@MOF membrane layer, wherein the NF@MOF membrane layer is an NF membrane on which an MOF material is grown in situ. In the present invention, the separator layer is combined with the NF@MOF membrane layer, and the in-situ grown MOF material provides high ionic conductivity and low interfacial impedance, such that the prepared composite separator integrates high mechanical strength, high flexibility, high electrolyte wettability, a high liquid retention rate and excellent ionic conductivity; and the synergistic effect exerted by the components of the composite separator can promote the uniform deposition and stripping of lithium metal, suppress the growth of lithium dendrites, and prevent separator penetration that may lead to a short circuit or even fire and explosion accidents, thereby prolonging the cycle life of the lithium metal battery and improving the safety performance thereof. Thus, the composite separator of the present invention has broad application prospects in terms of lithium metal batteries.

The composite membrane comprises a base membrane layer and a functional layer, the functional layer comprises at least two material layers which are arranged in a stacked mode, and the at least two material layers are selected from an inorganic ceramic layer, a solid electrolyte layer and a high-temperature-resistant polymer layer. The at least two material layers are arranged on at least one side of the base film layer; wherein the functional layer comprises a high-temperature-resistant polymer layer, and the high-temperature-resistant polymer layer is arranged on the surface of the base film layer; when the functional layer does not comprise the high-temperature-resistant polymer layer, the solid electrolyte layer is arranged on the surface of the base film layer. According to the composite diaphragm, the heat resistance of the diaphragm is improved, and the use safety of the lithium battery is improved.

The invention provides a biological nanopore sensor and a preparation method thereof. The method for preparing the biological nanopore sensor comprises the following steps: a) preparing hydrophilic protein into lipidosome; and b) mixing the lipidosome with the membrane layer to promote the lipidosome to be inserted into the membrane layer to obtain the biological nanopore sensor, and the hydrophilic protein has a nanopore channel. The method can solve the problem that the hydrophilic protein is difficult to prepare into the biological nanopore sensor in the prior art, and is suitable for the field of nanopore sequencing.

The invention provides a preparation method of a metal-based ceramic composite membrane with a catalytic ozone function. The preparation method comprises the following steps: preparing functional powder by taking tetrabutyl titanate as a titanium source and silver nitrate or ferric nitrate as a catalytic active metal source and adopting a sol-gel method; a porous metal pipe is used as a supporting body, metal powder and functional powder which are made of the same material as the supporting body are mixed to prepare functional slurry, the functional slurry is evenly deposited on the inner wall of the supporting body through vacuum filtration, and powder particles which are not firmly combined are removed through back flushing; and finally, the binding force between the functional film layer and the metal matrix is improved through high-temperature heat treatment. Wherein the thermal expansion coefficient difference between the metal supporting body and the functional film layer can be reduced by adding the metal powder, the metal powder is melted and diffused in the high-temperature heat treatment stage, and metallurgical bonding is formed between the functional powder and the metal substrate. The method is simple in process, and the prepared metal-based ceramic composite membrane has the advantages of being high in membrane layer binding force, not prone to falling off, high in catalytic activity, high in anti-pollution capacity, stable in operation and the like.

The invention provides an intelligent response nano-film and application thereof in waste lead-acid storage battery electrolyte recycling, and relates to the technical field of waste lead-acid storage battery electrolyte recycling, the intelligent response nano-film breaks through performance limitation of an existing film system through a specific intelligent material structure, and when heavy metal ions such as Pb < 2 + >, Fe < 3 + > and Cu < 2 + > enter the film, the intelligent response nano-film can be recycled, and the service life of the intelligent response nano-film is prolonged. The metal ligands are combined with metal ions to cause local shrinkage or closing of pore channels, so that the active defense and intelligent blocking effects of blocking heavy metals are achieved; and when SO4 < 2-> and H < + > pass through the channel, membrane pore channels are kept in an open state, so that rapid acid flux (namely the amount of substance passing through the membrane layer in unit time) of sulfuric acid is realized. The intelligent response nano film has a programmable aperture of a polymer liquid crystal network and an intelligent response valve mechanism of metal, and selective separation of heavy metal and sulfuric acid is realized by stimulating reversible adjustment of an induced film structure.

An implantable device for delivery of a macromolecular drug compound is provided. The device comprises a core having an outer surface and a membrane layer positioned adjacent to the outer surface of the core. The core comprises a core polymer matrix within which is dispersed a drug compound having a molecular weight of about 5 kDa or more, the polymer matrix containing a hydrophobic polymer. The membrane polymer matrix includes from about 70 wt. % to about 99 wt. % of an ethylene vinyl acetate copolymer.

Provided in the embodiments of the present application are a secondary battery and an electric device. In the secondary battery provided in the embodiments of the present application, the thickness Hc of a positive membrane layer of a battery, the contact angle θ of an electrolyte on a positive current collector, the weighted value a of a dielectric constant of an organic solvent in the electrolyte, and the total lithium-ion concentration M in the electrolyte are controlled, and the following relational expression is satisfied: 0.450≤(cosθ×a) / (M×Hc)≤0.792, so that the prepared secondary battery has lower self-discharge performance and better kinetic performance and cycle performance while meeting the requirement of high energy density.

The invention discloses a high-flux silicon carbide ceramic membrane filtering device, and belongs to the technical field of filtering equipment, the high-flux silicon carbide ceramic membrane filtering device comprises a guide cylinder unit and a rotating membrane cylinder unit, a dead end filtering station and a cross flow filtering station are arranged in the guide cylinder unit, and the rotating membrane cylinder unit is rotatably mounted in the guide cylinder unit; the two groups of silicon carbide ceramic membrane cylinders are rotatably mounted in the rotating membrane cylinder unit, pollutants on the surface of a membrane layer are cleaned by circularly switching the working states of the ceramic membrane cylinders, and the two groups of silicon carbide ceramic membranes can be always kept in a rotating state in the filtering process, so that the pollutants are uniformly distributed on the membrane layer; the deep deposition of pollutants in a specific area during dead-end filtration is avoided, and meanwhile, the two groups of membrane bodies are circularly switched between a dead-end filtration station and a cross-flow filtration station, so that the formation of a filter cake layer is effectively reduced, and the device is ensured to be in a high-membrane flux state.

A building system and corresponding method may include a building structure. A building system and corresponding method may include a building envelope membrane installed on the building structure, the building envelope membrane comprising: a first release liner, wherein the first release liner comprises: a first polymer, and a UV stabilizer, wherein the first release liner includes 1 wt. % to 90 wt. % of the UV stabilizer based on a total weight of the first release liner, wherein the first release liner is an outer layer, wherein the first release liner is removable, a first adhesive layer, a membrane layer, wherein the first adhesive layer is positioned between the first release liner and the membrane layer; and a second adhesive layer, wherein the membrane layer is positioned between the first adhesive layer and the second adhesive layer, wherein the second adhesive layer contacts the building structure.

The invention relates to the technical field of intermediate membranes, in particular to a heat insulation type ionic intermediate membrane and a preparation method thereof.The heat insulation type ionic intermediate membrane is characterized in that hollow silicon dioxide nanotubes serve as filler, epoxy resin modified polyurethane emulsion serves as a base material, auxiliaries are added to prepare a heat insulation coating, and the ionic intermediate membrane layer is coated with the heat insulation coating to form a heat insulation layer; the preparation method comprises the following steps: carrying out amination on a hollow silicon dioxide nanotube by using 3-aminopropyltriethoxysilane, carrying out dehydration condensation on furan-2, 5-diketone and an amino group to synthesize maleimide so as to obtain a maleimide modified hollow silicon dioxide nanotube, and grafting furan carboxylic acid imidazolium salt polyionic liquid by using a Diels-Alder reaction so as to obtain a composite hollow silicon dioxide nanotube; aminated glass fibers, composite hollow silicon dioxide nanotubes, epoxy resin modified polyurethane emulsion and auxiliaries are mixed, and a reinforcing layer coating is obtained; and coating the lower surface of the ionic intermediate film layer with a reinforcing layer coating to form the reinforcing layer.

A method for the production of an ion-conducting membrane for a water electrolyser or a fuel cell is provided. The method comprises the step of mixing a first liquid stream comprising an ion-conducting polymer and a second liquid stream comprising a cerium-containing compound in-line to form a coating composition. The coating composition is then deposited onto a substrate to form a membrane layer. An apparatus for the production of an ion-conducting membrane for a water electrolyser or a fuel cell is also provided.

The invention relates to a high-performance positively charged composite membrane and a preparation method thereof, in particular to a nanofiltration membrane containing a sulfonated imino covalent organic framework (TpPa-SO3H) interlayer. The nanofiltration membrane adopts a three-layer structure design, and comprises a base membrane layer, a TpPa-SO3H middle interlayer and a positively charged separation surface layer. Wherein the TpPa-SO3H interlayer is formed by in-situ growth of polyphenol and sulfated amine under the action of an oxidizing agent, and the separation surface layer is assembled and constructed through electrostatic attraction and hydrogen-bond interaction between positively charged polyelectrolyte and sulfonic acid groups. The TpPa-SO3H interlayer is introduced to effectively regulate and control the pore size distribution and hydrophilicity of the surface of the substrate, the formed negative electricity interlayer can promote the assembly of a polyelectrolyte positive electricity layer, and the interception performance and the operation stability of the composite membrane on heavy metal cations are remarkably improved. Compared with a traditional nanofiltration membrane, the composite membrane prepared through the method keeps high water flux (larger than or equal to 40 L.m <-2 >. H <-1 >. Bar <-1 >), meanwhile, the rejection rate of heavy metal cations such as Cr < 3 + >, Mn < 2 + > and Co < 2 + > is larger than or equal to 95%, and the composite membrane has excellent long-term operation stability. The preparation method is simple in process and low in cost, and has a wide application prospect in the field of heavy metal wastewater treatment.

The invention provides a nano-plastic detection device and method based on a magnetic adsorption-thermal cracking mass spectrometry technology, and solves the technical problem that the variety, content and physicochemical properties of nano-plastic in a water matrix are difficult to rapidly and accurately capture in the prior art. The pyrolysis device comprises a closed heating cavity, a resistance wire is wound on the closed heating cavity, the closed heating cavity is communicated with a carrier gas inlet pipe, a water vapor outlet pipe and a pyrolysis gas outlet pipe, and a sample groove is formed in the closed heating cavity; the sample introduction device comprises a sample introduction pipeline, and the sample introduction pipeline penetrates into the closed heating cavity in a sealed manner and is communicated with the sample groove; the groove bottom of the sample groove is a filter layer, the filter layer comprises a filter membrane layer, the filter membrane layer is connected to a ferromagnetic metal sheet, the aperture of filter holes of the filter membrane layer is smaller than the particle size of the nano-plastic, the heat-resistant temperature of the filter membrane layer is higher than the boiling point of the nano-plastic, and the ferromagnetic metal sheet is provided with a filtrate channel; the suction filtration device comprises a suction filtration head; the suction filtration head is communicated with the sample groove through a filter layer; the method can be widely applied to the technical field of nano-plastic pollution detection.

The present invention belongs to the field of preparation of nanofiber composite fabrics. The present invention provides a nanofiber high moisture permeability waterproof fabric with multi-level interconnected channels and a preparation method thereof. The fabric body includes an outer layer, an intermediate layer and an inner layer. The outer layer is a pure polyester waterproof fabric that has been waterproofed, the intermediate layer is a nanofiber membrane with multi-level interconnected channels, and the inner layer is a pure polyester fabric; the inner side of the outer layer of pure polyester waterproof fabric is bonded to the hydrophobic polyvinyl alcohol nanofiber membrane of the intermediate layer of nanofiber membrane with multi-level interconnected channels through hot melt adhesive compounding, and the inner layer of pure polyester fabric is bonded to the hydrophilic polyurethane nanofiber membrane of the intermediate layer of nanofiber membrane with multi-level interconnected channels through hot melt adhesive compounding. The nanofiber membrane with multi-level interconnected pores in the middle layer is composed of multiple nanofiber membrane layers stacked in sequence. Each nanofiber membrane layer has two layers of nanofiber membranes with different fiber diameters, one layer is a hydrophilic polyurethane nanofiber membrane, and the other layer is a hydrophobic polyvinyl alcohol nanofiber membrane. The nanofibers of the two membranes between and within the multi-level nanofiber membrane layers are cross-connected to form a three-dimensional structure with multi-level interconnected pores. The pore size gradually decreases from the hydrophilic polyurethane nanofiber membrane to the hydrophobic polyvinyl alcohol nanofiber membrane. The moisture permeability is higher than 15000g / (m 2 24h), the hydrostatic pressure is higher than 60kPa.

The invention discloses a neural microelectrode for electrical stimulation combined with drug release and a preparation method thereof.The neural microelectrode comprises a first flexible substrate layer, a drug-loaded slow-release layer, a second flexible substrate layer, a conductive layer and an insulating covering layer, and the drug-loaded slow-release layer contains chitosan microspheres embedded with drugs; the medicament comprises nerve growth factors and / or anti-inflammatory drugs, a plurality of drug release holes are distributed in the insulating covering layer, an electrode contact is arranged at one end of the conducting layer, a lead connector is electrically arranged at the other end of the conducting layer, and openings for exposing the electrode contact and the lead connector are correspondingly formed in the two ends of the insulating covering layer respectively. According to the neural microelectrode provided by the invention, the drug-loaded slow-release layer is integrated in the neural microelectrode, so that a space for storing a drug does not need to be additionally processed on the membrane layer, and the drug does not need to be additionally loaded, so that the production and processing are relatively convenient and rapid; after the neural microelectrode is implanted into a corresponding tissue in a body, the drug-loaded sustained-release layer can be gradually degraded to slowly release a medicament for repairing nervous tissues or avoiding rejection reaction in a long-acting manner.

The invention provides a single battery, a battery device and a power utilization device, the single battery comprises a laminated electrode assembly, the laminated electrode assembly comprises a positive pole piece, an isolating membrane and a negative pole piece which are laminated, the negative pole piece comprises a negative current collector and a negative membrane layer arranged on at least one side of the negative current collector, the positive pole piece comprises a positive pole current collector and a positive pole film layer arranged on at least one side of the positive pole current collector, the positive pole film layer comprises a positive pole active material, the positive pole active material comprises lithium-containing transition metal phosphate particles, the compaction density of the positive pole piece is 2.25-2.65 g / cm < 3 >, and the lithium-containing transition metal phosphate particles are uniformly distributed on the positive pole piece. In a particle roughness area cumulative distribution curve obtained by the tangent plane of the positive electrode film layer along the thickness direction of the pole piece, the roughness RA50 is 0.90-0.98, and the roughness RA90 is more than 0.93. The battery monomer can give consideration to both energy density and cycle performance.

The invention provides a secondary battery, a power utilization device and a binder, the secondary battery comprises a positive pole piece, a negative pole piece and an isolating membrane, the negative pole piece comprises a negative current collector and a negative membrane layer arranged on at least one surface of the negative current collector; the negative electrode film layer comprises a negative electrode active material and a first binder; the mass ratio of the negative electrode active material in the negative electrode film layer is 96%-98.4%; the mass ratio of the first binder in the negative electrode film layer is 0.5%-3%; the first binder includes a polymer including-COOM,-CONH2,-CN, and-COOR, where M includes an alkali metal, and R includes a substituted or unsubstituted C1-C20 alkyl group. The secondary battery in the present application has improved energy density and does not deteriorate processability.

The application relates to the technical field of batteries, in particular to a composite solid electrolyte membrane and a preparation method and application thereof. The composite solid electrolyte membrane comprises the following layers which are sequentially stacked: a first membrane layer comprising a polymer, a solid electrolyte and a lithium salt; a second membrane layer comprising a polymer, a solid electrolyte and a lithium salt; and a third membrane layer which is an interface layer; wherein the solid electrolyte and the lithium salt content of the second membrane layer are higher than those of the first membrane layer, and the polymer is formed by polymerization of raw materials comprising triacetyl cellulose (TCA) and polyvinylidene fluoride-hexafluoropropylene (PVDF-HFP). The composite solid electrolyte membrane has improved high-temperature resistance and good ion transmission performance.

The invention discloses a rigidity-variable interventional medical access catheter which comprises a catheter body and a handle, the catheter body comprises a lining tube, the lining tube is sleeved with a reinforcing tube, the reinforcing tube is sleeved with a supporting tube, and the supporting tube is covered with a flexible outer membrane layer capable of being filled and expanded; the handle comprises a first channel communicated with an inner hole of the lining pipe and a second channel communicated with a space between the supporting pipe and the flexible outer film layer, when a medium is filled through the second channel, the flexible outer film layer is attached to the outer surface of the supporting pipe, and when the medium is filled through the second channel, the flexible outer film layer is separated from the supporting pipe to form a separation space. Compared with the prior art, the separation space is formed between the outer membrane layer and the supporting tube to form buffering, so that the outer membrane layer has flexibility to reduce the rigidity of the catheter so as to facilitate conveying in a blood vessel, when the outer membrane layer is attached to the outside of the supporting tube, the separation space disappears, the rigidity of the catheter is increased, and the stability of the catheter is guaranteed; instruments such as embolism materials or supports can be accurately placed in place, and the treatment effect is improved.

The present disclosure refers to an in vivo analyte sensor, comprising: a substrate (20); a conductive layer (21) disposed over at least a portion of the substrate (20); a sensing layer (24) disposed formed on the conductive layer (21), wherein the sensin\g layer (24) forms a sensing area configured to generate one or more signals identifying a monitored analyte level after insertion of the analyte sensor and when maintained in fluid contact with interstitial fluid; and a membrane layer (25) formed at least on the sensing layer (24). The sensing layer (24) is formed with an area sensitivity of 0,2 to 1,5 nA / (mqx / dL) mm2 within the sensing area. Further, a method of manufacturing an in vivo analyte sensor is provided.

The invention provides a method and device for reducing coating defects of a disc-type ceramic membrane, and the method comprises the following steps: positively mounting a clamp on a spraying station, enabling the ceramic membrane to dynamically rotate, and cleaning and activating the front surface of the ceramic membrane by adopting a low-temperature plasma technology; carrying out negative pressure suction on the ceramic membrane while the ceramic membrane is dynamically rotated, and spraying a membrane preparation liquid on the front surface of the ceramic membrane by adopting ultrasonic atomization; and dynamically rotating the ceramic membrane, and performing negative pressure suction on the ceramic membrane, so that the circular arc part of the ceramic membrane is dynamically dip-coated in the membrane preparation liquid. According to the method, dynamic rotation of the ceramic membrane, negative pressure and ultrasonic spraying are cooperated, ultrasonic atomized liquid drops are sucked into a micropore structure or surface gaps when making contact with the surface of the ceramic membrane, pinholes or defects of the membrane layer are avoided, and the uniform, dense and defect-free membrane layer is formed; and non-contact with the ceramic membrane can be realized, and the coating defect caused by improper contact before the membrane layer is dried is effectively prevented.