84 results about "Creatinine" patented technology

The invention is a cosmetic or dermatological preparation with a content of an active agent combination comprising (a) at least one creatinine compound selected from the group consisting of creatinine and derivatives of creatinine; (b) at least one creatine compound selected from the group consisting of creatine and derivatives of creatine; and (c) at least one soybean compound selected from the group consisting of soybean germ extracts and ingredients which can be isolated from soybean germ. The present invention also includes methods for stimulating collagen synthesis of the skin, for restructuring or rejuvenation of the skin, and for inspiring the body or senses comprising applying the preparation to the skin.

The invention discloses a nested PCR (polymerase chain reaction) kit for detecting chicken-manure pollution in a water body and a detection method thereof, and belongs to the field of the detection of pollution in water bodies. The nested PCR kit for detecting the chicken-manure pollution in the water body comprises two pairs of nested PCR primers, dNTP (deoxyribonucleoside triphosphate), a PCR buffer, a Taq polymerase, a Mg<2+> solution and ddH2O (double distilled water). Two rounds of PCR amplification are used by a nested PCR method. The detection method comprises the following steps of extracting a DNA (deoxyribonucleic acid) in a water sample, and carrying out a first round of PCR amplification by using the DNA in the water sample as a template, wherein the primers are an SCF (stem cell factor) and SCR (serum creatinine); after a reaction is terminated, carrying out a second round of PCR amplification by using a product of the first round of PCR amplification as a template, wherein the primers are an NCF (neutrophil chemotactic factor) and NCR (nitrile chloroprene rubber), and after the second round of PCR amplification is terminated, detecting the existence of a 403bp strip, which shows that the water body is subjected to the chicken-manure pollution, through agarose gel electrophoresis. According to the method, the detection sensitivity is greatly increased through the nested PCR amplification; a little chicken-manure pollution which exists in water can be detected; moreover, the method has a favorable specificity, and can be directly applied to the detection and the preventive treatment work of fecal pollution in the water body.

The present invention is based on the finding that enrichment of isotope-labeled creatinine in a urine sample following oral administration of a single defined dose of isotope-labeled can be used to calculate total-body creatine pool size and total body skeletal muscle mass in a subject. The invention further encompasses methods for detecting creatinine and isotope-labeled creatinine in a single sample. The methods of the invention find use, inter alia, in diagnosing disorders related to skeletal muscle mass, and in screening potential therapeutic agents to determine their effects on muscle mass.