218 results about "Hair regeneration" patented technology

The invention discloses a traditional Chinese medicine preparation for treating alopecia and a preparation method thereof. The traditional Chinese medicine preparation for treating alopecia of the invention is prepared from the following medicinal materials of, by weight, main drugs comprising 12-18 parts of angelica sinensis, 8-12 parts of radix rehmanniae recen, 8-12 parts of fructus ligustri lucidi, 8-12 parts of semen cuscutae, 8-12 parts of matrimony vine, 4-6 parts of Chinese honey locust, 12-18 parts of polygonum multiflorum, 8-12 parts of semen sesami nigrum, 8-12 parts of ginger, 4-6parts of eclipta, 8-12 parts of cacumen biotae, 12-18 parts of mulberry, 8-12 parts of fructus cnidiiand, and 3-5 parts of borneol, and adjuvants of emu oil and alligator oil, wherein mass concentration of emu oil in the traditional Chinese medicine preparation is 4%-6%, and mass concentration of alligator oil in the traditional Chinese medicine preparation is 6%-8%. The preparation of the invention has efficacies of tonifying qi and nourishing the blood, promoting blood circulation and removing blood stasis, stimulating the menstrual flow and promoting blood circulation, breeding and nourishing hair, dispelling wind and arresting itching, activating occlusive hair follicle, and promoting hair regeneration. In addition, inflammation of scrubbing place can be avoided, and scar and ecchymosis formation rate is low.

The invention discloses application of mesenchymal stem cell exosome to preparation of a drug preparation for promoting hair regeneration. Mesenchymal stem cells are prepared by the following method:separating and extracting the mesenchymal stem cells from an umbilical cord and then obtaining the mesenchymal stem cells through primary culture and subculture. The application of the mesenchymal stem cell exosome to preparation of the drug preparation for promoting the hair regeneration, disclosed by the invention, has the advantages that skin tissue structures on alopecia areata can be improvedby adopting the mesenchymal stem cell exosome, and hair follicles in the stationary phase in the skin tissue on the alopecia areata can be promoted to be transformed to a growing period; and the hairregeneration on the alopecia areata can be promoted. The application prospect of the mesenchymal stem cell exosome in preparation of the drug preparation for promoting the hair regeneration is broad.

The present invention relates to a device for stimulating hair growth comprising an outer casing (1) with a first hold end (2) of the device, a second stimulating end (3) and start-up means (6). At the second stimulating end (3) are located at least one laser lighting element (4) and at least one LED lighting element (5). Said laser lighting elements (4) emit a wavelength between 600 and 900 nm, and LED lighting elements (5) a wavelength between 400 and 600 nm. Thus, through laser lighting elements (4) is achieved stimulating the hair regeneration

The invention relates to the technical field of stem cells and hair loss treatment, and in particular relates to a hair regeneration method for mesenchymal stem cell-induced alopecia areata and an application. The invention provides a new application of the mesenchymal stem cells, namely the application of the mesenchymal stem cells in preparation of products for hair regeneration of induced alopecia areata, the hair regeneration method for the mesenchymal stem cell-induced alopecia areata, and an animal model for hair regeneration after alopecia areata built by the method. The hair regeneration method can be applied to hair follicle regeneration research and alopecia areata treatment.

The invention provides a preparation method of a cell nutrient solution for promoting hair regeneration. The preparation method mainly comprises three steps: 1) primary isolation of ADSCs (adipose-derived stem cells); 2) enlarged cultivation of the ADSCs; and 3) induced culture of the ADSCs. The cell nutrient solution prepared by the invention can solve the problem of alopecia from the point of cell regeneration; the ADSCs-conditioned medium (the nutrient solution), in a periodic hair follicle reconstruction process, can activate a stem cell microenvironment of hair follicle and can regulate and control the normal growth of the hair follicle; by conducting low-dose UVB radiation, ADSCs survival, migration and paracrine capacities can be significantly improved, and an angiogenesis capacity and a hair regeneration capacity can be also obviously improved; by cultivating the ADSCs with a fibroblast-conditioned medium, cell survival and metabolism processes in a body environment can be simulated, and the secretion of more cell factors, which are conducive to cell microenvironment regulation and control, from cells can be promoted; and meanwhile, the cell nutrient solution prepared by the method is convenient in cell preparation, broad in source and convenient for clinical popularization, and cells can be derived from fat wastes obtained from clinical liposuction and skin grafts removed in other surgical operations.

The invention discloses a hair regeneration membrane device and a use method thereof. The hair regeneration membrane device includes a helmet body, wherein a helmet body is composed of an outer helmetshell and an inner helmet shell; a first air bag and a second air bag are respectively installed in the sandwich cavity at the two sets of arc-shaped grooves; an ultraviolet lamp is fixedly installedon the upper surface of the second convex side edge at the position of the first air bag; a wind box is fixedly installed on the out surface of the outer helmet shell at the position of the air inlet; a fan is fixedly installed in the wind box, a liquid storage cylinder is fixedly installed in the middle of the upper surface of the out helmet shell; and a semicircular massage head is arranged below the threaded shaft pipe. The hair regeneration membrane device is comfortable to wear, is able to adjust the tightness of wearing, as that semi-circular massage head is attached to the scalp to massage the scalp; in the process of the hair growth liquid acting on the scalp, the air permeability of the scalp can be maintained by fan exhaust air; and meanwhile, the scalp contact with bacteria inthe air of the scalp can be avoided by ultraviolet lamp sterilization, and scalp infection can be avoided.

The invention discloses hair follicle curing shampoo with hair regeneration factors and a preparation method thereof. The hair follicle curing shampoo is prepared from the following raw materials in parts by weight: 0.5 to 1.5 parts of an EGF (Epidermal Growth Factor), 35 to 50 parts of ginger juice, 6 to 18 parts of traditional Chinese medicine extracting solution, 4 to 11 parts of caffeine, 3 to7 parts of trehalose, 2 to 7 parts of vitamin E, 4 to 10 parts of mint essential oil, 3 to 8 parts of rosemary essential oil, 2 to 6 parts of laurinol polyether ammonium sulfate, 1 to 5 parts of disodium cocoyl glutamate, 2 to 7 parts of sodium cocoyl amino-propionate, 3 to 8 parts of cocamidopropyl hydroxyl sulphobetaine, 0.5 to 1.5 parts of lauryl glucoside, 0.4 to 1.8 parts of potassium sorbate, 0.5 to 2.0 parts of citric acid and 1.5 to 4.5 parts of hexadecyl trimethyl ammonium chloride. The EGF, the ginger juice, the traditional Chinese medicine extracting solution, the caffeine, the trehalose, the vitamin E, the mint essential oil, the rosemary essential oil, the laurinol polyether ammonium sulfate, the disodium cocoyl glutamate, the sodium cocoyl amino-propionate, the cocamidopropyl hydroxyl sulphobetaine, the lauryl glucoside, the potassium sorbate, the citric acid and the hexadecyl trimethyl ammonium chloride can be used as the raw materials of the hair follicle caring shampoo through scientific proportioning, and the hair follicle caring shampoo is capable of curing scalp, moistening hair follicles and growing dense hairs while the hairs can be effectively cleaned.

The present invention relates to a Chinese medicine liniment for external application for curing alopecia and promoting hair regeneration. It is made up by using 13 Chinese medicinal materials of ginseng, astragalus root, Chinese angelica root, salvia root, flavescent sophora root and others through a certain preparation process. Its effective rate is 93.6%.

A hand held device generates a predetermined number of pulses of light having a predetermined electromagnetic spectrum, a predetermined duration, a predetermined inter-pulse interval, and a predetermined total energy. The pulse sequence is delivered to a skin surface to temporarily remove hair. A period of time for reappearance of hair on the selected skin surface after the using of the device to remove hair from the selected skin surface is determined by counting the days to hair reappearance after a test light application. Subsequently, the device is used periodically to apply the pulses of light to the selected skin surface at intervals of shorter length than the determined period of hair regeneration, thereby temporarily maintaining the selected skin surface free of visible hair.

The invention relates to an injection capable of treating androgenetic alopecia with dermal papilla cell exosomes. The injection is a normal saline solvent containing dermal papilla cell exosomes. A preparation method of the injection comprises fiver steps including dermal papilla cell separation, dermal papilla cell adherent culture, dermal papilla cell stimulation induced culture, exosome freezedried powder preparation, and injection preparation. The amount of the exosomes secreted by the dermal papilla cells prepared using the preparation method is large, the content of effective components capable of promoting hair regeneration is high, and the treatment effect of the injection on androgenetic alopecia is excellent.

The invention discloses active peptide composition for promoting hair growth. The active peptide composition comprises peptide of a stimulating keratin gene and collaborative short peptide, wherein the collaborative short peptide is one or more of leucine-proline-arginine, proline-leucine-arginine, isoleucine-proline-arginine, lysine-Isoleucine-proline, proline-isoleucine-lysine or valine-glutamine-proline. The active peptide composition can actively recognize keratinocyte, hair follicle immune cells and the stimulating keratin gene, has multiple effects of hair regeneration, new hair anchoring stability and the like, can collaboratively remarkably increase hair and particularly has effects of increasing and thickening eyelash. The invention also discloses a hair growth promoting preparation containing the active peptide composition and an application of the hair growth promoting preparation in the field of cosmetics.

The invention relates to anti-hair-loss shampoo and a preparation method thereof. The anti-hair-loss shampoo is prepared from the following substances in parts by weight: ethylenediamine tetraacetic acid disodium salt, guar hydroxypropyltrimonium chloride, butanediol, disodium laureth sulfosuccinate, cocamide MEA, trihydroxystearin, cetanol, sodium cocoyl alaninate, cocamidopropyl hydroxysultaine,vitamin B family raw materials, polydimethylsiloxane, laureth-23, laureth-3, an anti-hair-loss plant extract, phenoxyethanol, ethylhexylglycerin, essence, citric acid, sodium chloride and deionized water. The anti-hair-loss shampoo has the effects of nutrition and repair on hair, through long-term use, hair scales are moistened, thus the hair is not prone to breaking off and can be further dark and bright, the growth vitality of hair follicle cells is improved, hair regeneration is promoted, the hair follicle metabolism function is enhanced, and hair loss is effectively prevented.

The invention relates to an external Chinese medicinal preparation for preventing hair loss and promoting hair generation, which can inhibit hair loss and promote hair regeneration. The external Chinese medicinal preparation is prepared mainly by brewing the following Chinese medicinal components in alcohol: tuber fleeceflower root, Chinese angelica, safflower, lightyellow sophora root, fresh ginger and the like, is applied on scalp at a position of hair loss, increases the nutrition and activity of hair mother cells and recovers the physiological function of hair follicles by regulating the local microenvironment of the hair, and solves the problems of difficult hair regeneration and difficult long-term regeneration maintenance in alopecia areata, alopecia totalis and hair loss.

The invention relates to a hair regeneration formula. The hair regeneration formula comprises radix astragali, radix angelicae sinensis, galla chinensis, radix polygoni multiflori, cacumen platycladi, herba ecliptae, rhizoma polygonati, rhizoma zingiberis recens slices, semen sesami nigrum, rhizoma chuanxiong, semen glycines nigrae and fructus ligustri lucidi. A preparation method for the hair regeneration formula includes steps of drying various raw materials, smashing the various dried raw materials and uniformly mixing and stirring the smashed raw materials to obtain mixed powder; decocting the mixed powder in water, and filtering medicines residues after the mixed powder is completely decocted so as to obtain medicine liquid; adding alcohol into the medicine liquid, uniformly mixing and stirring the alcohol and the medicine liquid to obtain mixed liquid, allowing the mixed liquid to stand still, clarifying the mixed liquid and filtering impurities to obtain clear liquid; adding glycerin into the clear liquid. The hair regeneration formula and the preparation method have the advantages that the various raw materials in the hair regeneration formula are organically combined with one another, accordingly, effects of stimulating blood circulation of heads, enhancing the immunity of the heads, promoting hair regeneration and blackening hair can be realized, and gray hair and hair loss due to senescence can be delayed.

An object of the present invention is to promote hair growth or hair regeneration by promoting formation and/or regeneration of hair follicles. A method is provided for promoting formation and/or regeneration of hair follicles, comprising maintaining or increasing expression of one or a plurality of genes involved in cell adhesion in dermal papilla cells.

The invention provides a dog food additive with hair-beautifying and hair-brightening effects and a preparation method thereof, as well as dog foods containing the dog food additive with hair-beautifying and hair-brightening effects. The dog food additive with hair-beautifying and hair-brightening effects is mainly prepared from the following ingredients: allicin, lecithin, seaweed powder, and linseeds. The dog food additive with hair-beautifying and hair-brightening effects provided by the invention is highly targeted and specific, as well as comprehensive in functions; and the dog food additive is capable of achieving targeted improvements on dog hair health so as to guarantee dog skin health and moistened state, promote skin cell viability and hair regeneration, and improve brightness and softness of dog hairs.

The invention relates to an anti-dandruff shampoo containing folium mori and rosemary. The preparation method of the anti-dandruff shampoo containing folium mori and rosemary comprises the following steps of smashing fresh folium mori and rosemary into paste by a pulverizer, then adding distilled water and ethyl alcohol into the pasty rosemary and stirring, centrifuging, taking the centrifugate for standby application, after squeezing a centrifugal object, taking the squeezed juice, and combining the squeezed juice with the centrifugate to obtain liquor A; stewing the folium mori juice with the distilled water and filtering; reserving leachate, combining three leachates, concentrating, sterilizing to obtain liquor B; combining the liquor A with the liquor B so as to prepare the anti-dandruff shampoo containing folium mori and rosemary. The anti-dandruff shampoo not only maintains the nutrient substances of the folium mori and the rosemary, but also has the effects of anti-dandruff, hairdressing, hair care, repairing, and hair regeneration.

According to tea bran silicone-oil-free shampoo and a preparation method thereof, rosemary essential oil is adopted, so that the effects of realizing strong astringing, resisting wrinkles and regulating cortex can be achieved, greasy and unclean skin can be conditioned, blood circulation can be promoted, hair regeneration can be stimulated, and loose skin after weight loss is firmer; lemon grass essential oil is adopted, so that the shampoo has very good effects of resisting depression, resisting bacteria, killing bacteria, removing flatulence, removing odor, helping digestion, killing mould,preventing diseases, realizing stimulating, tonifying body and the like, and is beneficial to relieving itching; and tea bran extract is adopted, so that the shampoo has the effects of removing hair oil, treating head itching, removing dandruff, relieving alopecia, promoting hair growth and blackening and brightening hair.

The hair growing water for stopping hair loss and scurf is prepared with 12 kinds of Chinese medicinal materials, including arborvidae leaf, schizonepeta herb, ledebouriella root, asarum herb, lily magnolia, etc. The present invention prepares the externally applied liquid with Chinese medicinal materials with functions of contracting sweat pore, dispelling the surficial evil, dispelling wind evil and heat, stopping hair loss based on the Chinese medicine theory of treating internal disease externally. The externally applied liquid is applied for head to stimulate the cell activity of hair, promote metabolism, promote vital energy and blood circulation in head and promote hair regeneration, and has excellent treating effect and no side effect.

The invention discloses a hair growth inducer, which comprises an active ingredient composed of tofacitinib and minoxidil with a mass percentage of 0.1:99.9-99.9:0.1. The hair growth inducing agent provided by the invention, its active ingredient comprises tofacitinib and minoxidil, wherein tofacitinib is a kind of JAK inhibitor, can interact with target cells (such as dermis, epidermis, dermal papilla cells or hair follicles) Cell) specific protein active site selectively binds, inhibits the transmission of cell pathway signals and the synthesis of characteristic cytokines, thereby reducing the symptoms associated with hair loss diseases; Minoxidil is a potassium ion channel opener that can directly relax Vascular smooth muscle has a powerful dilation effect on small arteries, reduces peripheral resistance, promotes the growth of hair follicle cells, and thus regenerates hair; the combination of these two substances synergistically acts on the target protein of target cells and vascular smooth muscle, and inhibits cytokines Synthesis and accelerated blood circulation, in order to achieve a significant effect of promoting hair regeneration.

The invention discloses a traditional Chinese medicine preparation for treating seborrheic alopecia. The preparation comprises the following active pharmaceutical ingredients in parts by weight: 10-20 parts of frankincense, 10-20 parts of pilose asiabell root, 10-20 parts of processed tuber fleeceflower root, 10-20 parts of Chinese angelica, 10-20 parts of Indian buead, 10-20 parts of diverse wormwood herb, 10-20 parts of fiveleaf gynostemma herb, 10-20 parts of barbary wolfberry fruit, 10-20 parts of mulberry fruit, 10-20 parts of Chinese arborvitae twig, 10-20 parts of common macrocarpium fruit, 10-20 parts of radix salviae miltiorrhizae, 10-20 parts of red paeony root, 10-20 parts of baical skullcap root, 10-20 parts of nutgrass galingale rhizome and 10-20 parts of simpleleaf shrub chastetree fruit. The traditional Chinese medicine preparation disclosed by the invention has the effects of inducing resuscitation, refreshing, activating qi-flowing, expelling stagnation, suppressing hyperactive liver, invigorating kidney, disinfecting, sterilizing, benefiting qi, activating blood, opening pores, nourishing scalp and regenerating hair. The traditional Chinese medicine preparation has a special hair regeneration efficacy against seborrheic alopecia, alopecia after serious illness, neurasthenia alopecia and the alopecia caused by fungal infection. The traditional Chinese medicine preparation realizes scientific compatibility of various active ingredients of the traditional Chinese medicine preparation, has the advantages of fast onset of action, no toxicity or side effects and lasting effects and can relieve the suffering of a patient to a relatively great extent.