184 results about "Physiological function" patented technology

The invention relates to the technical field of data processing, and discloses an old people health state assessment data processing system based on multi-modal data, and the system comprises a medical data integration module which obtains electronic medical record data and a medical examination report through an FHIR interface, and extracts a structured health index; the cross-modal causal fusion processing module is used for fusing the monitoring data and the medical text through an image, text and image interlayer architecture; the health state evolution modeling module is used for mapping the health feature vectors into physiological function, cognitive level and athletic ability three-dimensional state indexes; an evaluation report backtracking module; and a decision output module. Through an image, text and image interlayer architecture, deep semantic fusion of multi-modal features is realized under the constraint of medical pathology rules, feature weight adaptive distribution is dynamically guided based on a medical causal atlas, a high-dimensional fusion vector retaining key pathology information is generated, the semantic integration ability of health data is remarkably improved, and the health data fusion efficiency is improved. And the reliability of discrimination and decision making is improved.

The invention relates to the technical field of bioactive peptides, in particular to a novel multifunctional collagen-like tripeptide and application thereof, an amino acid sequence contains multiple combinations, X can be selected from multiple components, 3-methoxy-4-hydroxyphenylalanine and the like are added, and the novel multifunctional collagen-like tripeptide can interact with specific proteins, activate related pathways and play multiple physiological functions and is applied to multiple fields. The collagen-like tripeptide has obvious advantages, innovates component expansion functions, improves the preparation method, improves the efficiency, reduces the cost, is matched with other components in the fields of beauty, health care and medicine, enhances the efficacy, realizes targeted delivery, and brings a new opportunity to related industries.

The application relates to the technical field of data processing, and discloses an old person health state evaluation data processing system based on multi-modal data, which comprises a medical data integration module, an across-modal causal fusion processing module, a health state evolution modeling module, a backtracking evaluation report module and a decision output module. The medical data integration module acquires electronic medical record data and medical examination reports through a FHIR interface and extracts structured health indexes. The across-modal causal fusion processing module fuses monitoring data and medical texts through an image, a text and an image sandwich architecture. The health state evolution modeling module maps a health feature vector into three-dimensional state indexes of physiological functions, cognitive levels and motor abilities. The backtracking evaluation report module and the decision output module are used for backtracking evaluation and decision output. Through the image, the text and the image sandwich architecture, deep semantic fusion of multi-modal features is realized under the constraint of medical pathology rules, feature weight adaptive distribution is dynamically guided based on a medical causal graph, a high-dimensional fusion vector retaining key pathological information is generated, the semantic integration capability of health data is significantly improved, and the reliability of discrimination and decision is improved.

The invention belongs to the technical field of biomedicine, and relates to a method for constructing a mouse embryo-derived hypothalamic organ model and application, the invention proposes that a mouse embryo is used for constructing a hypothalamic organ for the first time, and the mouse embryo has a definite development time sequence and genetic operability; the naturally retained vascular endothelial cells and multilineage precursor cells provide unique advantages for constructing a three-dimensional organ containing multiple nucleuses such as a preoptic region, a paraventricular nucleus, an arcuate nucleus and a supraoptic nucleus, and the model not only breaks through the nucleus coverage limitation of the existing iPSCs organ, but also can be used for constructing the three-dimensional organ containing multiple nucleuses such as the preoptic region, the paraventricular nucleus, the arcuate nucleus, the supraoptic nucleus and the like by reconstructing a nerve-blood vessel unit. High-fidelity simulation of complex physiological functions of the hypothalamus is realized, and an irreplaceable technical platform is provided for mechanism analysis of neuroendocrine diseases and high-throughput screening of drugs.

The invention relates to the technical field of medical information analysis, in particular to a thoracic surgery postoperative complication assessment method and system based on multi-dimensional analysis, and the method comprises the following steps: S1, obtaining a postoperative multi-dimensional monitoring data set; s2, performing standardized preprocessing on the multi-dimensional monitoring data set to generate standardized monitoring data; s3, classifying and integrating the standardized monitoring data into physiological function data, drainage feature data and motion perception data according to data types; s4, chest dynamic pressure change analysis is carried out, and pressure gradient change parameters are calculated; s5, obtaining an abnormal metabolite ratio index; and S6, generating a complication risk assessment report. According to the method, through standardized integration and weighted analysis of the multi-dimensional postoperative monitoring data, accurate quantitative evaluation and graded output of the thoracic surgery postoperative complication risk are realized, and the reliability of early warning and the timeliness of clinical intervention are improved.

The invention discloses a chest wall defect three-dimensional reconstruction and personalized repair material design system, and relates to the technical field of intelligent medical aided design. Comprising a data acquisition module used for acquiring and preprocessing multi-modal data of the chest wall of a patient; the partition module is used for dividing the defect area into different functional partitions by coupling and analyzing stress and blood flow data and setting a threshold value; the dynamic optimization module is used for mapping the breathing time sequence to a three-dimensional space and dynamically correcting the partition boundary according to the stress change in the breathing cycle; the interface matching module is used for carrying out parameterization design on a host bone interface according to the bone mineral density data; and the optimization design module is used for carrying out topological structure and pore distribution dual optimization on the repair material based on the dynamic partition and the interface parameters, and finally, the output module generates design data capable of directly driving manufacturing. Precise matching of the repairing material and the physiological anatomical structure and the dynamic physiological function of the patient is achieved.

The invention relates to a tissue engineering articular cartilage simulating a four-layer structure of a natural cartilage and an in-situ 3D printing method of the tissue engineering articular cartilage, the structure and component characteristics of'surface layer-transitional layer-radiation layer-calcification layer 'of the natural cartilage are re-carved through precise layered modeling and layer-specific bio-ink, and the articular cartilage is obtained by means of an optimized in-situ 3D printing process. The tissue engineering cartilage which is matched with dissection of a defect area and consistent with mechanical and physiological functions of natural cartilage is directly constructed in an articular cavity. Besides, the in-vitro induced differentiation step of the BMSCs is reduced, the risk of cell mutation is reduced, meanwhile, the long-term integration of the repaired tissue and the host cartilage is improved, and the problem that the long-term effectiveness of clinical repair is insufficient is solved.

The embodiment of the invention provides an intelligent cabin control method, device, equipment and program product, and the method comprises the steps: collecting the multi-modal data of a driver, and generating a cross-modal feature according to the multi-modal data; the multi-modal data comprises image data and physiological time sequence signal data, inputting the cross-modal features into a classification model, determining an output result of the classification model as a physiological state of the driver, the physiological state comprising a physiological function state and an emotional state, generating an intervention strategy according to the physiological state of the driver, and controlling the intelligent cabin according to the intervention strategy. By identifying the physiological state of the driver, the information most concerned by the driver at present is accurately judged, so that the intelligent cabin is accurately controlled.

The utility model relates to the technical field of ancient and famous tree protection, and discloses an ancient and famous tree hole filling and repairing structure which comprises a repairing frame, an adjusting frame is arranged on one side of the repairing frame, groove cavities are formed in the repairing frame and the adjusting frame, and movable wheels are arranged in the groove cavities; the movable mechanism is located on the opposite side of the repairing frame and the adjusting frame, the movable mechanism comprises an inserting assembly, a control assembly and a positioning assembly, the inserting assembly is located on the opposite side of the repairing frame and the adjusting frame, and the control assembly is located on one side of the inserting assembly; through the arrangement of the movable mechanism, tree holes in different positions in the same circumference of an ancient tree can be repaired, frequent dismounting and mounting are not needed, the situation that the tree holes continuously exist is avoided, the repairing efficiency of the device is improved, the flexibility of the device is improved, and meanwhile the problems that in an existing device, tree holes in different positions are difficult to repair, and the repairing efficiency is poor are solved. The normal physiological functions of the trees are affected.

This application relates to a device for detecting organ function and its control method, as well as a dietary management method and system, belonging to the technical field of medical device testing. The control method compares and analyzes changes in the microscopic features of the same area of ​​the tongue before and after eating, and calculates the corresponding metabolic index change rate, constructing a mapping relationship between the tongue's microscopic morphology and organ function, providing a basis for assessing internal physiological function through external characterization. Simultaneously, the dietary management method uses physiological responses before and after eating as real-time biofeedback signals to generate dynamically adjusted dietary management plans, forming a personalized health management closed loop of "monitoring-assessment-intervention-remonitoring," achieving precise adaptive adjustment of intervention strategies.

The invention relates to the technical field of biological medicine, and relates to a polypeptide in targeted combination with SOX2 protein and application thereof, the polypeptide has an amino acid sequence as shown in SEQ ID NO.1, or has at least 85%, 90%, 95% or more than 99% of sequence identity with the amino acid sequence; the polypeptide inhibits phase separation of SOX2, liquid drops formed by phase separation of SOX2 can be avoided, then the situation that the liquid drops wrap chemotherapeutic drugs, influence the curative effect of the chemotherapeutic drugs and cause tolerance of tumor cells to the chemotherapeutic drugs is avoided, and the polypeptide does not influence the transcription activation function of SOX2 serving as a transcription factor; the polypeptide can inhibit the phase separation of the SOX2, so that the regulation of normal physiological functions, such as high expression in organs such as eyes of a human body, of the SOX2 as a transcription factor is not influenced, and therefore, the polypeptide disclosed by the invention can reverse chemotherapy drug resistance of tumors such as squamous carcinoma by inhibiting the phase separation of the SOX2, can be used for adjuvant therapy of the tumors such as squamous carcinoma, and has no obvious toxic or side effect on each organ of an organism.

The utility model relates to the technical field of breeding, and particularly discloses a breeding environment adjusting device which comprises a breeding room body, a gauze element and a cover plate, a ventilation opening is formed in the top of the breeding room body, a sliding groove is formed in one side of the inner wall of the ventilation opening, and a connecting block is slidably connected into the sliding groove; by arranging the cover plate, the gauze elements, the guide grooves, the guide assemblies and the sliding assemblies, the sliding assemblies can drive the cover plate to slide so as to drive the gauze elements to move, the guide assemblies guide sliding of the cover plate, lighting can be conveniently conducted in the breeding house body, and the breeding house is convenient to use. Meanwhile, when reverse operation is carried out, the cover plate can be closed, the heat preservation performance of the breeding room body is improved, and the situation that the livestock suffers from diseases due to the fact that the body temperature of the livestock is reduced due to insufficient heat preservation is reduced is reduced.

To provide a biomimetic system that mimics the human proximal tubule, which is a high-performance in vitro model that can reproduce the physiological functions of the human proximal tubule in vitro and can be used as an evaluation tool in drug discovery.SOLUTION: The present invention provides a proximal tubule biomimetic system comprising a microfluidic device and LTL-positive cells derived from pluripotent stem cells contained within the microfluidic device. The microfluidic device has (A) a device body, (B) a first chamber provided in the device body, (C) a second chamber provided in the device body, and (D) a porous membrane positioned between the first chamber and the second chamber, separating the first chamber from the second chamber. The LTL-positive cells are contained within the first chamber and adhere to a first surface of the porous membrane facing the first chamber. The first surface of the porous membrane is coated with an extracellular matrix.SELECTED DRAWING: None

The invention discloses a treatment auxiliary device after obtaining of a transplanted donor lung, and belongs to the field of medical instruments, the treatment auxiliary device comprises an anastomat, the anastomat is provided with a handle, a forceps head and a shaft rod connecting the handle and the forceps head, and the forceps head comprises a nail abutting seat and a nail bin which can be meshed with each other to clamp tissue; the suction pipeline is provided with a suction end used for extending into an air pipe and a negative pressure connecting end used for being connected with a negative pressure source, and the suction pipeline comprises a first pipe section extending along the shaft rod; the air inflation pipeline is provided with an air injection end used for introducing air into the lung and an oxygen injection connecting end used for being connected with an air source, and the air inflation pipeline comprises a second pipe section extending along the shaft rod; the suction end and the air injection end are both arranged on the near side of the forceps head. By means of the arrangement, sputum suction, lung inflation and trachea clamping and closing operation can be completed after the donor lung is obtained and before transplantation, and therefore the physiological function and structural integrity of the donor lung are maintained.

The invention discloses an integrated guide control method for a prostate dilation catheter, relates to the technical field of medical treatment, solves the problem of highly integrating two core links of'guide 'and'control' in an operation, and realizes simplification of operation, accuracy of positioning and controllability of mechanical parameters, so that the treatment effect is ensured, and the operation cost is reduced. According to the technical scheme, the method is characterized by comprising the following steps that firstly, preoperative measurement and planning are carried out; 2, a catheter is placed in and initially positioned; 3, integrated guiding and accurate anchoring are carried out; the prostate dilation device has the advantages that the prostate dilation operation is successfully converted from a complex technology which highly depends on experience and equipment to an advanced treatment mode which is standardized, quantitative, minimally invasive and excellent in function protection through unique integrated guide and control design, and revolutionary improvement is brought to multiple dimensions of curative effect, safety, function and efficiency.

The invention relates to a bemisia tabaci gene BtCOX8 and application thereof, and belongs to the field of biological control. The gene BtCOX8 highly expressed in the bemisia tabaci is screened, dsRNA is synthesized for the gene, the dsRNA is dripped on the body surface of nymphs of the bemisia tabaci, the nymphs are obviously shrunken and wizened, are in an obvious dehydration state and show the characteristics of growth resistance and serious physiological function disorder, and the results show that the BtCOX8 is a potential efficient RNAi lethal target. The dsRNA synthesized by the invention can be used for biological control of bemisia tabaci, is safe to encarsia formosa and orius minutus which are natural enemies of the bemisia tabaci, has the advantages of environmental friendliness and the like, and has a good application prospect.

The invention relates to the technical field of poultry breeding, and particularly discloses a staged efficient forced feeding method and feed for white ducks, and the forced feeding method comprises the following steps: selecting white ducks with the day age of 65 days and the initial weight of 3.6-4.2 kg as forced feeding objects; according to the method, the white ducks are subjected to continuous forced feeding for 27 days, the forced feeding period is divided into a first-stage adaptation period, a second-stage pressurization period and a third-stage sprint period, each stage lasts for 9 days, the three-stage forced feeding design accurately matches the natural law that the physiological function and the metabolic load of the white ducks in the forced feeding period are gradually increased, and the physiological function of the white ducks is improved. The stress impact caused by forced feeding of the traditional single high-energy feed is effectively avoided. Through rhythm control of early-stage low-load adaptation, middle-stage stable pressurization and later-stage efficient sprint, and in combination with the pineapple peel fermented bio-enzyme preparation added in the adaptation stage, the early-stage stress response, digestive system disease incidence and death rate of the ducks are remarkably reduced.

The invention relates to a method for constructing a last-stage atherosclerotic plaque through additive manufacturing, and belongs to the technical field of tissue engineering. According to the method, firstly, cells are treated, then bio-ink for a fiber cap, bio-ink for a lipid nucleus and bio-ink for a suspension pool are prepared respectively, and then construction of the last-stage atherosclerotic plaque is completed through curing treatment. After a conditional culture solution and a stimulating factor are added, long-term in-vitro culture can be realized, and a real focus microenvironment can be simulated. The fibrous cap-lipid nucleus AS plaque constructed by the invention can maintain the stability and physiological function of the structure for a long time, and can accurately simulate hyperplasia, hypoxia, fat enrichment and inflammatory response of the AS plaque in the last stage.

This invention belongs to the field of medical devices, specifically a combined internal fixator and fixation method for fixing joints with micro-motion. The combined internal fixator includes a first bone screw and a second bone screw. A movable connecting structure is provided between the connecting ends of the first and second bone screws. The movable connecting structure includes a groove and a shaft. The groove includes an insertion port and a mounting groove communicating with the insertion port. The mounting groove has a semi-circular cross-section. The shaft includes a semi-circular shaft adapted to the mounting groove, which is rotatably accommodated within the mounting groove, allowing the first and second bone screws to rotate relative to each other around a first radial axis. This invention, through a hook-groove sliding self-locking structure, achieves controllable micro-motion and integrated implantation for fixing joints with micro-motion. It has achieved significant technological advancements in preserving joint physiological function, simplifying surgical procedures, avoiding secondary surgeries, and reducing the incidence of complications. It has important clinical application value and is suitable for fixing joints with micro-motion.

Systems, methods, and computer code products monitor the behavior, health, and / or characteristics of an animal. In one implementation, the animal is positioned inside a waste container placed on a system that is adapted to determine, record and communicate over a network various animal health parameters. These parameters can be processed to determine trends, statistics and changes of animal physiological functions. The results can be used to access animal health conditions and issue warnings, alarms, messages, and other notifications to designated caretakers. These notifications may be displayed using various means such as computers and / or mobile devices. Data retrieval and review capability can provide improved understanding of an animal's health conditions and facilitate early illness detection.

The utility model discloses an electrically-driven multifunctional cardiopulmonary model, relates to the field of teaching models, and particularly aims to solve the problems that in the prior art, in the teaching process of an existing teaching double-lung model, only arteries and other structures and the distribution condition of lung segments can be determined, and the teaching efficiency is low. In order to solve the problems that in the prior art, in the prior art, the whole process of lung gas exchange, lung circulation and alveolar change cannot be further dynamically simulated, and the working process of the heart and the lung cannot be vividly restored, the utility model provides an electrically-driven multifunctional heart and lung model which is scientific and vivid, meets more teaching contents, enables a solid model to be dynamic, enables the lung physiological process to be visualized, and improves the teaching efficiency. The main physiological functions of the lung are simulated through various lights, the basic anatomical structure and the dynamic physiological process are combined, the lung anatomical structure and the physiological functions are comprehensively displayed, the discipline barrier is broken, learning and understanding of students are facilitated, and the higher teaching requirements at present are met.

1. Name of the product in this design: Main body of a desktop semiconductor laser physiotherapy device. 2. Purpose of this design: By irradiating blood with low-intensity laser, a series of biochemical reactions are triggered in the human body, thereby improving and restoring the physiological functions of blood through both blood circulation and blood stasis. 3. The key point of the design of this product lies in its shape. 4. The picture or photo that best illustrates the design points: three-dimensional picture.

Computational methods are used to create cardiovascular simulations having desired hemodynamic features. Cardiovascular modeling methods produce descriptions of blood flow and pressure in the heart and vascular networks. Numerical methods optimize and solve nonlinear equations to find parameter values that result in desired hemodynamic characteristics including related flow and pressure at various locations in the cardiovascular system, movements of soft tissues, and changes for different physiological states. The modeling methods employ simplified models to approximate the behavior of more complex models with the goal of to reducing computational expense. The user describes the desired features of the final cardiovascular simulation and provides minimal input, and the system automates the search for the final patient-specific cardiovascular model.

The invention relates to the technical field of flower cultivation, and discloses a cultivation method of phalaenopsis amabilis, which comprises the following steps: before low-temperature induction treatment, performing admission verification on a plant population by analyzing gas metabolism response characteristics of the plant population in a diagnostic dark environment; after verification is passed, controlled metabolic consumption is performed on the plant population, osmotic pressure stress pulses are cooperatively applied during the period to synchronize root activity, and then synchronization energy accumulation is performed; according to the method, systematic physiological function regulation and control including admission verification are carried out on plant populations, passive adaptation to biological individual differences in traditional cultivation is converted into active and whole-plant-dimension physiological state standardization, and therefore the certainty of the cultivation process is fundamentally converted into industrial process control from biological randomness, and the cultivation efficiency is improved. And the predictability and the consistency of production are improved.

This invention relates to an intraoperative nerve localization system for thoracic sympathectomy, belonging to the field of minimally invasive surgical assistance and medical information processing technology. During thoracoscopic surgery, this system identifies and analyzes candidate regions of the thoracic sympathetic nerve by acquiring intraoperative thoracoscopic images and patient physiological signals. It also verifies the sympathetic nerve properties of the target structure by combining the physiological functional responses induced by intraoperative nerve stimulation. Based on this, the system fuses and calculates the image structural information and functional response information to generate the localization reliability of the thoracic sympathetic nerve, providing the surgeon with localization references and safety prompts for thoracic sympathectomy. This system enables real-time, objective localization of the thoracic sympathetic nerve during surgery, reducing reliance on surgeon experience, lowering the risk of mis- or missed sympathectomy, and improving the safety and consistency of thoracic sympathectomy, thus possessing high clinical application value.

The invention discloses an information processing method and device for extracting anorectal pressure frequency domain characteristics, equipment and a medium, relates to the technical field of medical instruments, is applied to a computer device and is used for receiving original pressure information of various anorectal channels at different acquisition time points, and the original pressure information is acquired by an anorectal pressure measuring catheter; integrating the original pressure information of various anorectal channels under a target analysis time window to obtain a time domain pressure signal; performing short-time Fourier transform on the time domain pressure signals to obtain power spectral density of the pressure signals of various anorectal channels in the target analysis time window; and based on a target frequency band corresponding to the target analysis time window, extracting frequency domain features related to anorectal physiological functions from the power spectral density. And the frequency domain characteristics in anorectal pressure measurement are accurately extracted.

The present invention provides a plastic composition, comprising at least one plastic and at least one plasticizer. The plastic comprises polylactic acid, the plasticizer comprises an amide ester compound, and the amide ester compound has biodegradability. The weight percentage of the plastic in the plastic composition is 85% to 99.99%, and the weight percentage of the plasticizer in the plastic composition is 0.01% to 15%. Thus, the plastic composition of the present invention can reduce damage to the environment and ecology by the biodegradable polylactic acid and the plasticizer characteristics, and has excellent biodegradability and good plasticizing effect by the specific mixing ratio. Furthermore, by designing the plasticizer structure similar to the estrogen, the plasticizer can prevent affecting normal physiological functions.

The invention belongs to the technical field of path planning, and discloses a gynecological tumor multidisciplinary combined operation path planning system and method. The method comprises the following steps: acquiring first focus image data from a gynecological tumor operation site, evaluating a first physiological function parameter of a patient state, and processing a first operation state parameter of an operation doctor to obtain a first combined operation path planning feature; constructing a multidisciplinary combined operation path planning model by using the first combined operation path planning feature and a corresponding first tumor operation planning method, inputting a second combined operation path planning feature of a target to be operated into the model to obtain a second tumor operation planning method, and performing reference by combining physiological parameters such as images and electroencephalogram. The method is advantaged in that a tumor operation path planning suggestion is acquired, a long-time operation doctor is assisted to carry out path selection, doctor fatigue and operation comfort are reduced, operation path management is accurately carried out, and an operation completion rate is improved.

This utility model relates to the field of orthopedic implant technology and discloses a prosthesis for defects after partial atlas resection. It aims to solve the problems of existing technologies, such as the lack of atlas prosthesis implants, long recovery times after autologous bone grafting, and the ineffective fixation of titanium mesh implants. This utility model includes a prosthesis that replaces the atlas, with bone screw holes to accommodate bone screw fixation contact points. The prosthesis includes an outer frame, which is a porous tubular or porous columnar structure. The cavity of the porous tubular structure is filled with autologous bone, allogeneic bone, or artificial bone. The upper and lower ends of the outer frame are provided with curved surfaces matching the facet joints of the occipital condyle and axis, and a support unit is provided within the outer frame. This utility model, combined with 3D printing technology, matches the shape of the corresponding segment and resection site, thereby replacing the resected segment, promoting the fusion of the atlantoaxial segment, and facilitating the restoration of the physiological function of the upper cervical spine.