9results about How to "Lower eye pressure" patented technology

The invention discloses an eye implant which comprises an implant body, the implant body is in a strip shape, the outer contour of the upper surface of the implant body is in a protruding arch shape or a semi-arch shape and used for making contact with a sclera, and the lower surface of the implant body is in a plane shape and used for making contact with a choroid; a longitudinal drainage groove is formed in the upper surface of the implant body in the front-back direction of the implant body. The whole implant body is of a structure that the front end and the rear end are gradually thin and the middle is thick or the rear end is gradually thin and the middle is thick to the front end, the implant body can smoothly enter the suprachoroidal space, an originally narrow gap of the suprachoroidal space is expanded, the outflow amount of aqueous humor from the suprachoroidal space is increased through the longitudinal drainage grooves, the drainage effect is good, blocking is not prone to occurring, and the application range is wide. The effect of reducing the intraocular pressure is achieved. The lower surface of the implant body is planar, so that the attachment area of the implant body and the choroid is larger, the implant body can be stably attached to the choroid, the risk of displacement of the anterior chamber and the choroid is reduced, the implant body is prevented from being exposed to the anterior chamber to touch the cornea, and the risk of loss of corneal endothelial cells is reduced to the maximum extent.

The invention provides an NO donor type dasatinib derivative as well as a preparation method and application thereof. The derivative is one of a compound 1a-1f and a compound 2a-2f; the derivative has multiple effects of removing senescence cells, reducing intraocular pressure and protecting optic nerves, and is a novel potential treatment medicine for treating glaucoma and senescence-related retinopathy.

The application discloses a glaucoma drainage device and belongs to the technical field of medical devices. The glaucoma drainage device comprises a drainage sheet, the inside of which is a cavity structure, the drainage sheet is divided into a left cavity and a right cavity through a first partition plate, the upper surface of the left cavity is provided with a drainage hole, and the first partition plate is provided with a drainage opening; a drainage assembly is in communication with the inside of the drainage sheet through a connecting hole provided on the drainage sheet; and a fixing mechanism is arranged on the drainage sheet and used for fixing the drainage sheet and the drainage assembly. The glaucoma drainage device can fix the drainage assembly and the drainage sheet of the device through a mechanical fixing structure, avoids the problems of the suture fixation of the drainage device in the prior art, simplifies the operation process, shortens the operation time, reduces the complications caused by the suture foreign matter, and improves the fixing reliability and safety.

The present invention discloses a silicone hydrogel contact lens material and its preparation method and application. The silicone hydrogel contact lens material includes the following raw materials by weight: 0.2-0.8 parts of L-arginine zwitterion derivative monomer, 40-80 parts of hydrophilic monomer, 20-40 parts of siloxane monomer, 0.5-2 parts of initiator, and 0.5-2 parts of cross-linking agent. The L-arginine zwitterion derivative of the present invention has dense guanidine active sites. By combining it with the contact lens material, it can intelligently respond to the reactive oxygen generated in the microenvironment of the inflammation site of the eye, continuously release NO, reduce ROS, and alleviate eye inflammation. The preparation method of the present invention is simple and efficient. The L-arginine zwitterion derivative monomer, hydrophilic monomer, and siloxane monomer initiate double bond polymerization under ultraviolet light irradiation, so that the compound is more stable, not easy to be eluted, and has excellent biocompatibility performance. The continuously released NO can reduce intraocular pressure and nourish the visual nerve.

The invention discloses a traditional Chinese medicine composition for treating glaucoma and a preparation method thereof, and relates to the technical field of traditional Chinese medicine preparations. The traditional Chinese medicine composition is prepared from the following components in parts by weight: 5 to 15 parts of fructus lycii, 2 to 10 parts of flos chrysanthemi, 5 to 15 parts of radix rehmanniae recen, 2 to 10 parts of fructus corni, 5 to 15 parts of rhizoma dioscoreae, 5 to 15 parts of poria cocos, 2 to 10 parts of cortex moutan, 2 to 10 parts of salted rhizoma alismatis, 2 to 10 parts of lucid ganoderma, 2 to 10 parts of fried fructus broussonetiae and 2 to 10 parts of rhizoma acori graminei. The traditional Chinese medicine composition has the effects of nourishing kidney and liver, nourishing yin and promoting salivation, clearing liver and improving vision, and promoting qi circulation and inducing diuresis, and is used for treating blurred vision, eye swelling and pain and uncomfortable eyes caused by glaucoma.

The invention discloses a capsular bag tension ring assembly which comprises a capsular bag tension ring, a suture line and a suture needle, one end of the suture line is connected with the capsular bag tension ring, and the other end of the suture line is connected with the tail of the suture needle. The invention further discloses a using method of the capsular bag tension ring assembly, and the using method comprises the following steps that S1, the capsular bag tension ring is stored in a releaser needle tube, and the suture line and the suture needle are located outside the needle tube; s2, one end of a suture is fixed to the capsular bag tension ring, then the suture and the capsular bag tension ring are implanted into the lens capsular bag together, and the suture is adjusted to be located in the center of the dislocation capsular bag; and S3, inserting a needle from the main incision, penetrating through the anterior chamber and passing through the rear part of the iris, withdrawing the needle from the edge of the keratosclera, fixing the capsular bag tension ring by using a suture technology after withdrawing the needle, and keeping the lens capsular bag, the capsular bag tension ring and a suture in the center and constant, so that the artificial lens is safely implanted and the dislocation condition is corrected. The invention is mainly used for maintaining the stability of the lens capsular bag in the moderate and severe lens imperfect dislocation operation.

The present application relates to the technical field of surgical knives, and discloses a trabeculectomy knife with adjustable knife distance, which comprises a knife handle, a knife rod connected with the knife handle, and a knife head connected at the end of the knife rod, wherein the knife head is boat-shaped, has a knife tip and two side edges, the rear sections of the two side edges are connected and the front ends thereof meet at the knife tip, the knife head has a concave cavity, the concave cavity is provided with a chevron-shaped gap for separating the knife tip, a pair of parallel first sliding grooves are arranged in the side wall of the concave cavity, an arc-shaped plate is slidably arranged in the first sliding grooves, and the two parallel edges of the arc-shaped plate are respectively clamped in the two first sliding grooves. The trabeculectomy knife can realize mode switching of the knife head and width adjustment of the side edges by single-handed holding, the big thumb can accurately control power transmission by rotating the knob, the friction fit of the threaded transmission and the wedge structure ensures smooth movement without slipping, and the operation difficulty is reduced without the need for additional instrument assistance or double-handed operation.

The utility model discloses a device capable of forming an opening in the trabecular meshwork of the eye, comprising a handle, a cutting element, a sheath tube and a pushing element, the cutting element comprises an elongated rod and two cutting blades, the tail of the elongated rod is fixedly connected with the head of the handle, and the head of the elongated rod is connected with the two cutting blades; the two cutting blades are symmetrically arranged with a predetermined opening, and the head of each cutting blade has a cutting part capable of penetrating into the trabecular meshwork and cutting the trabecular meshwork; the sheath tube is sleeved on the elongated rod and can slide along the elongated rod; the pushing element is connected with the handle and can drive the sheath tube to move towards the direction of the two cutting blades, so that the two cutting blades are closed to each other under the extrusion of the sheath tube to cut the trabecular meshwork, the cut tissue is easy to be peeled off from the trabecular meshwork, the cut part of the trabecular meshwork can form a trabecular meshwork opening, and the aqueous humor in the anterior chamber is promoted to flow out of the trabecular meshwork opening to reduce the intraocular pressure; and the size of the trabecular meshwork opening can be controlled during the cutting process.

The application provides a corneal path one-way aqueous humor outflow device, which is internally formed with a Tesla valve unit group outflow channel for draining aqueous humor to an ocular surface, and the outflow channel is one-way outflow. The aqueous humor outflow device provided by the application introduces a Tesla valve as a structure for preventing backflow of aqueous humor, and when liquid flows into the Tesla valve unit group from a liquid outlet, the Tesla valve unit group can block the liquid from flowing to a liquid inlet. The aqueous humor outflow device provided by the application also has the following advantages: it can be used for reducing intraocular pressure of glaucoma patients and can also be used for severe dry eye; it is made of a material with good biocompatibility, has high drainage efficiency in clinical application, has the advantages of compact structure, convenient 3D printing modeling and forming, low cost and convenient use.