1161 results about "Cornea" patented technology

The invention discloses an intelligent control method and system for AR equipment, and the method specifically comprises the steps: determining a pupil center position coordinate and a cornea reflection point position coordinate of a user according to an eye image of the user, and inputting the pupil center position coordinate and the cornea reflection point position coordinate into a geometric mapping model for matching, obtaining user sight direction information; acquiring image brightness value distribution of an area near a user fixation point, determining a plurality of candidate saliency areas according to the image brightness value distribution, and comparing the candidate saliency areas with a preset saliency area template to determine a user attention focus; and acquiring head posture information of the user in real time by adopting a head posture tracking algorithm, and dynamically controlling the shooting direction of a camera of the AR equipment according to the head posture information, the sight direction information of the user and the attention focus of the user. According to the method and the device, accurate alignment of the AR content and the visual focus of the user is realized, and the immersion and interaction experience of the AR application are greatly improved.

The invention relates to recombinant III-type humanized collagen and application of a composition containing the same to eyes. The invention provides an application of recombinant III type humanized collagen in preparation of a product for preventing and / or treating eye inflammation, a composition containing the recombinant III type humanized collagen, and an application of the composition in preparation of a product for preventing and / or treating eye inflammation and / or eye dryness. The recombinant III-type humanized collagen and the composition containing the recombinant III-type humanized collagen can obviously promote updating and repairing of corneal epithelial cells, and meanwhile, can inhibit release of inflammatory mediators, enhance eye tissue barriers, enhance tear film stability and relieve eye inflammation and eye dryness.

The invention provides a subjective optometry prediction method combining wavefront aberration and optical signals. According to the method, eyeball wavefront aberration data are measured through a wavefront sensor, cornea, crystal and retina biological parameters are obtained by combining multi-view-field scanning of a galvanometer system, and after high-credibility data points are screened, a gradient refractive index eyeball three-dimensional model is constructed by adopting an NURBS algorithm; using finite element analysis to optimize cornea stress distribution, iteratively correcting the model through a deformation energy function, and dynamically compensating eyeball motion errors based on eye movement tracking data; and generating a multi-field-angle visual chart image through ray tracing simulation, and predicting a subjective optometry result in combination with an image quality evaluation algorithm. According to the method, high-precision modeling, dynamic error suppression and intelligent simulation technologies are fused, the optometry prediction accuracy, the personalized adaptation degree and the dynamic scene adaptability are remarkably improved, and an efficient and reliable solution is provided for refraction correction.

Shape-stabilized collagen scaffolds and methods of obtaining such scaffolds are disclosed. Stroma can be harvested, for example, from human or porcine corneal stroma and shaped during excision or in a separate step after excision. Following shaping (and preferably decellularization), the excised stroma portion is subject to pressure, force or vacuum to reduce fluid content and then irradiated or otherwise treated to induce crosslinking of collagen chains or fibrils. In one embodiment, the scaffold can be compacted by removing some or all of the water from the scaffold, and rehydrating the scaffold in a controlled manner (e.g., in a mold or other confining space) such that the scaffold takes a desired compacted shape; and then crosslinking at least a portion of the scaffold to mechanically strengthen it and inhibit subsequent swelling. Various sources of energy can be employed to induce crosslinking of collagen including, for example, ultraviolet (UV) radiation. The scaffolds can also be selectively densified or patterned. The invention is particularly useful in forming stable lenticules of enhanced stiffness and sufficient optical clarity for intracorneal implantation in additive ocular surgery.

Surgical treatment of glaucoma involves creation of a sclerocorneal drainage channel, ensuring long-lasting controlled fluid flow and reduced intraocular pressure. Limitations relate to collateral damage to adjacent structures and outcomes being heavily reliant on the surgeon's expertise. The device described herein addresses such shortcomings. The device comprises a grasping body having a longitudinal axis, and a piercing member coupled to the grasping body, including an elongate body and a beveled piercing tip including a long side and a short side, wherein the piercing member includes a proximal segment, a distal segment, and an aperture nested between the proximal segment and the distal segment, wherein the short side and the aperture are coaxially disposed along a central longitudinal axis of the piercing member, and wherein the piercing member is configured to reciprocate along the longitudinal axis relative to the grasping body.

The embodiment of the invention discloses a visual field tracking method and device, and the method achieves the differential weight fusion of an image through a first infrared image set, greatly reduces the influence of a tear film, a lens scratch, a cosmetic contact lens line and other interference factors, improves the recognition accuracy of a cornea reflection point, and improves the sight tracking precision. The combined methods of FFT confidence analysis, RANSAC algorithm verification, Kalman filtering, median filtering and the like are adopted, interference of pseudo spots and dynamic noise is effectively reduced, and the stability and reliability of cornea reflection point detection are remarkably improved. The self-adaptive enhancement technology and the ROI accurate extraction method are adopted, so that the method can better adapt to eye feature differences of different users and various complex actual environments and illumination conditions, and the universality of the visual field tracking device is enhanced. Differential fusion, feature recognition, confidence verification and filtering processing are automatically carried out in the whole process, and manual intervention is not needed.

An arrangement for tracking a position of an individual's eye comprises: (a) a frame mountable on a head of an individual; (b) at least one visually transparent element mounted within the frame in a the field of view of an eye of the individual; (c) at least one infrared light source configured for emitting an infrared light beam; (d) an image sensor configured for capturing images of the eye; (e) a processing unit configured for controlling the infrared light source and the image sensor and detecting a pupil position and a corneal reflection within images captured the at least image sensor. The transparent element comprises a spectrally-selective layer configured for reflecting the infrared beam. The visually transparent element is configured for selectively directing the infrared beam onto the eye and directing an infrared radiation reflected from a pupil and cornea of the eye to the image sensor.

This invention discloses a 2D gaze point estimation method based on the pupil-corneal reflection vector method. It utilizes the star ray method for pupil center localization and adds a classification pupil detection mechanism for error correction. Corneal feature extraction is performed to obtain the center coordinates of the corneal reflected light spot. Step 4: Establish a gaze mapping model, and assign the detected pupil-corneal reflection vector V(V) to each frame of the image. x V y The gaze coordinates G(G) mapped onto the screen x G y This invention enables 2D gaze point estimation based on the pupil-corneal reflection vector method. Compared with existing technologies, this invention can improve the accuracy of 2D gaze point estimation.

The invention belongs to the technical field of regenerative medicine, and provides a circular cornea embedded micro lens, which comprises two areas, namely a first correction area and a plano area, preferably comprises three areas, namely two vision correction areas and a plano area, the two vision correction areas have the vision correction effect, the diopter of the plano area is 0D, and the diopter of the first correction area is 0 D, and the diopter of the plano area is 0 D; wherein the flat light area is provided with a through hole, and the applicant summarizes and finds that the through hole is formed in the center of the cornea embedded microlens, so that the phenomena of nebula and turbidity of the cornea after operation can be reduced. After the cornea embedded microlens provided by the invention is implanted, a patient can clearly see near objects and distant objects, so that clear vision is realized. The invention further provides a preparation method and application of the cornea embedded microlens.

The invention relates to the field of surgical robots, and particularly discloses an intraoperative risk assessment system for a cataract surgical robot, comprising: a patient biomechanical monitoring unit for collecting a contact force between an instrument and an eye tissue, and calculating an anterior chamber equivalent pressure value according to an axial force component of the contact force and a contact area between the instrument and a cornea; the patient optical imaging monitoring unit is used for collecting microstructure images of the cornea and the lens capsule and quantifying the energy release density of ultrasonic emulsification; the robot motion parameter monitoring unit is used for collecting joint motion resistance, instrument tail end three-dimensional coordinates, motion speed and attitude angle of the robot; the multi-mode joint reasoning unit is used for identifying a high-risk operation state when the contact force is higher than a first preset value and the energy release density is higher than a second preset value; by adopting the technical scheme of the invention, multi-dimensional real-time monitoring can be realized, and a dynamic risk prediction model can be established by fusing heterogeneous data through an intelligent algorithm.

The utility model relates to the technical field of contact lenses, and particularly discloses a comfortable sclera lens which comprises an outer surface, the inner side of the outer surface is connected with an optical area, the periphery of the optical area is sequentially provided with a first transition area, a second transition area and a landing area, the first transition area and the second transition area are connected with each other, and the optical area is not in contact with the cornea. A plurality of liquid guide grooves are evenly formed in the inner side of the landing area at intervals, the inner ends of the liquid guide grooves penetrate through the first transition area and the second transition area and extend to the edge of the optical area, through holes are formed in the positions, close to the edge of the landing area, of the bottoms of the liquid guide grooves, and the through holes penetrate through the landing area. According to the sclera lens, the plurality of liquid guide grooves are formed, tear exchange between the sclera lens and the periphery of the eyes can be achieved after the sclera lens is worn, the situation that the eyes are dry after the sclera lens is worn for a long time is relieved, meanwhile, the through holes are formed in the inner sides of the liquid guide grooves, the tear exchange efficiency can be further improved through the through holes, the oxygen permeation rate can be improved, and the comfort degree is high when the sclera lens is worn.

The invention relates to the technical field of femtosecond laser, and discloses a multifunctional ophthalmology femtosecond device and a use method, and the device comprises a scanning imaging module which is used for emitting a detection light beam and carrying out OCT imaging; the femtosecond laser scanning module is used for receiving the detection light beam and irradiating the detection light beam to the target tissue; the femtosecond laser scanning module is also used for generating femtosecond laser and focusing the femtosecond laser to the target tissue; the operating microscope module is used for receiving the detection light beam and irradiating the detection light beam to a target tissue; the operating microscope module is also used for carrying out microscope imaging. According to the method, the optical coherence tomography technology is fused, more imaging information is added on the basis of an original visible light image, the re-alignment precision can be effectively improved, and the problem that a separation hook enters a wrong corneal lens layer is avoided.

Improvements in capturing an image of a cornea with Placido's disk lines are disclosed. The imaging is with a clam shell clamping device that is easily clamped onto a cellular device and the lighting tube is centered on the camera so the image at the end of the tube can be captured. The clamping device includes a ring light source that illuminates the outside of the tube with an internally reflective cone. The tube has a plurality of geometrically spaced light and dark rings to create evenly spaced rings on the cornea. Imperfections in the cornea will distort the rings. The camera can capture the image and the image or picture can be forwarded to a doctor or other care giver to determine the perfection or imperfection of the cornea and tear film break-up device.

A device for evaluating exophthalmia includes a left displacement platform, a left canthal latch point, a left mirror, a camera, a near infrared light source, a right canthal latch point, a right mirror, a right displacement platform, a visible light column and a shell or housing. A method for evaluating exophthalmia includes positioning the outer canthus of the eye, emitting light from the near-infrared light source and successively emitting light from multiple visible light columns, recording video of the eyeball looking straight ahead through the camera, and obtaining the video frame of the longest reflected light of the visible light columns on the eyeball in the mirror from the video; The corneal vertex is determined from the video frame, and the pupil center is determined by a neural network. The exophthalmia is calculated from known positions and the mirror tilt angle, the corneal vertex, and the pupil center.

Methods and systems for a model eye unit. In one example, the model eye unit includes a lens assembly removably attached to an anterior scleral casing and a middle section removably coupled to the anterior scleral casing. In the model eye unit, the middle section is removably and height adjustably coupled to a posterior scleral section and the lens assembly includes a cornea lens.

According to the nitrogen hydrochloride # imgabs0 # stine eye drops for treating allergic conjunctivitis and the preparation method of the nitrogen hydrochloride # imgabs0 # stine eye drops, the prepared eye drops can interact with the mucous layer on the surface of keratoconjunctiva by selecting specific solid lipid and a surfactant and controlling the dosage of the solid lipid and the surfactant; the retention capacity of the medicine in front of the cornea is prolonged, so that the medicine has good targeting property, the continuous release of the medicine is realized, the medication frequency can be reduced, the toxic and side effects of the medicine are reduced, the bioavailability is improved, the medication compliance of a patient is enhanced, and in the preparation and long-term storage processes, the medicine has better stability, and is suitable for popularization and application. Therefore, the problems of excessive drug due to multiple administration and poor stability of the active component nitrogen hydrochloride # imgabs1 # stine are solved.

The invention belongs to the technical field of regenerative medicine, and provides a circular partitioned micro lens for cornea implantation, which comprises two areas, namely a first correction area and a plano area, preferably comprises three areas, namely two vision correction areas and a plano area, the two vision correction areas have the vision correction effect, and the plano area has the vision correction effect. The diopter of the plano area is 0D, the plano area is provided with a through hole, and the applicant summarizes and finds that the through hole is formed in the center of the micro lens for the partitioned cornea implantation, so that the phenomena of nebula and turbidity of the cornea after operation can be reduced. After the partitioned micro lens for cornea implantation provided by the invention is implanted, a patient can clearly see near objects and distant objects, so that clear vision is realized. The invention further provides application of the partitioned micro lens for cornea implantation in vision correction.

The invention discloses a device and method for simulating eyelid scraping and intraocular pressure loading and monitoring suture tension, and relates to the technical field of medical instrument testing, the device comprises an eyeball environment simulation part and a suture cornea loading part, the suture cornea loading part comprises a scraping assembly and a transmission assembly, the eyeball environment simulation part comprises an intraocular pressure bubbling instrument, a hydraulic pipe, a T-shaped pipe and a tear pipe, the tear pipe is communicated with the scraping assembly, an opening in the lower end of one side of the T-shaped pipe is connected with the intraocular pressure bubbling instrument through the hydraulic pipe, and an opening in the lower end of the other side of the T-shaped pipe is provided with a hydraulic sensor. According to the device and method for simulating eyelid scraping, intraocular pressure loading and suture tension monitoring, the uniformity of cornea suture is achieved, secondary cornea damage caused by uneven suture is reduced, the risk of postoperative complications is reduced, and an experimental basis is provided for research and development of cornea substitutes.

The invention provides a machine learning and deep learning combined calibration-free eye movement tracking system and method, and the system comprises the following modules: a pre-calibration module which is used for collecting a near-to-eye image of the eyes of a user through a near-to-eye camera and an infrared light source, extracting pupil center coordinates and cornea reflection point coordinates, and outputting the pupil center coordinates and the cornea reflection point coordinates; calculating a personalized kappa angle of the user based on the extracted pupil center coordinates and cornea reflection point coordinates; the decision maker module adopts an AdaBoost ensemble learning algorithm, classifies the users according to the kappa angle obtained through calculation, and outputs a corresponding weight combination; and the deep learning module is used for receiving the output weight combination and the real-time near-eye image, and predicting the coordinates of the fixation point of the user through a convolutional neural network and a residual connection structure. According to the invention, the application flexibility and user friendliness of the eye movement tracking technology are greatly enhanced while the precision is guaranteed.

The present application relates to the field of smart wearable devices. Provided are a light source position calibration method, a device and a storage medium. The method comprises: using an image collection apparatus to collect user eye images; extracting from the eye images corresponding light spot two-dimensional coordinates and light spot three-dimensional coordinates of light spots formed by a light source, and, on the basis of the light spot two-dimensional coordinates, determining corresponding light source two-dimensional coordinates of the light source; and, on the basis of the light source two-dimensional coordinates, the light spot three-dimensional coordinates and preset coordinate parameters, determining corresponding light source three-dimensional coordinates of the light source, so as to calibrate the light source position of the light source in a smart wearable device on the basis of the light source three-dimensional coordinates. The present application calculates a position of a light source device on the basis of light spots formed by the light source in cornea areas of eye images, thus reducing the complexity of light source position calibration.

Transcorneal and fiberoptic laser delivery systems and methods for the treatment of eye diseases wherein energy is delivered by wavelengths transparent to the cornea to effect target tissues in the eye for the control of intraocular pressure in diseases such as glaucoma by delivery systems both external to and within ocular tissues. External delivery may be affected under gonioscopic control. Internal delivery may be controlled endoscopically or fiberoptically, both systems utilizing femtosecond laser energy to excise ocular tissue. The femtosecond light energy is delivered to the target tissues to be treated to effect precisely controlled photodisruption to enable portals for the outflow of aqueous fluid in the case of glaucoma in a manner which minimizes target tissue healing responses, inflammation and scarring.

The invention relates to the technical field of eye medical instruments, in particular to an adsorption fixing device for corneal cross-linking and a using method.The adsorption fixing device comprises an adsorption fixing device body, a cross-linking cavity is formed in the center of the adsorption fixing device body, a transparent cover plate is arranged at the top of the cross-linking cavity, and a negative pressure adsorption cavity is coaxially formed outside the cross-linking cavity; the adsorption fixing device is provided with an adsorption skirt outside the negative pressure adsorption cavity, a cross-linking through hole of the cross-linking cavity is communicated with a cross-linking agent pipeline, a pressure applying through hole of the cross-linking cavity is communicated with a pressure applying pipeline, a cleaning through hole of the cross-linking cavity is communicated with a cleaning pipeline, and a negative pressure through hole of the negative pressure adsorption cavity is communicated with an air exhaust pipeline. According to the adsorption fixing device for cornea cross-linking and the use method, the tensile strain of the cornea which is in a tensile state under the action of intraocular pressure originally is reduced or even inverted into compressive strain, so that the non-deformability of the cornea is improved through cross-linking, and the curvature of the cornea can be reduced.

The trabecular incision knife with the built-in chamber angle mirror comprises a pair of handles and a pair of operating heads arranged at the front ends of the handles, the handles are movably hinged through a connecting part, and the hinged point is located at the joint of the handles and the operating heads corresponding to the front ends of the handles. The pair of operation heads can be opened or closed by taking a hinge point as an axis; and a trabecular incision knife part and a specular reflection part are respectively arranged at the end parts of the pair of operating heads. According to the utility model, the built-in chamber angle mirror and the trabecular incision knife are combined for use, the knife and the mirror are integrated, the operation can be completed under direct vision only by making a single corneal incision with the width of 2.5-3mm, the chamber angle can be observed without using the chamber angle mirror, and the chamber angle incision or the trabecular incision can be completed under the direct vision; the utility model has the advantages of convenience in use, high operation safety, short operation time and short learning curve of a doctor, improves the working efficiency, relieves the pain of a patient, and reduces the occurrence rate of operative complications.

According to the cornea confocal high-speed imaging dislocation distortion correction system provided by the invention, the diaphragm for providing position reference is additionally arranged on the main image plane in the cornea confocal scanning imaging light path, and the dislocation image is corrected through the position of the diaphragm in the imaging process; high-speed bidirectional image dislocation distortion caused by a non-ideal motion state of the resonance galvanometer is overcome, and bidirectional high-speed scanning imaging is realized.

To perform analysis processing of pattern index images more accurately.SOLUTION: An ophthalmologic apparatus includes pattern index projection means for projecting a pattern index to obtain the corneal shape of an eye to be examined onto the cornea of the eye to be examined, image acquisition means for acquiring an anterior segment image by capturing an image of the anterior segment of the eye to be examined onto which the pattern index is projected using an image sensor, and processing means for processing the anterior segment image acquired by the image acquisition means. The processing means extracts a pattern index image corresponding to the pattern index projected onto the eye to be examined by comparing and processing at least two anterior segment images having different projection states of the pattern index, and analyzes the corneal shape of the eye to be examined on the basis of the extracted pattern index image.SELECTED DRAWING: Figure 3

The utility model discloses a light feeding instrument to solve the problem that retina light damage is possibly caused after long-term use in the prior art, and meanwhile, the treatment effect is also improved. Compared with the prior art in which only parameters such as red light source power and emergent light beam size are concerned, the utility model focuses on the important index of irradiance (power density), emergent light is a collimated Gaussian beam and the optical characteristics of eyes (a human eye refraction system is equivalent to a convex lens with a focal length of 17.2 mm). An optical component diffuser is additionally arranged at the position close to the cornea of a user, so that a collimated Gaussian beam is converted into diffused light to enter the eyes of the user, and diffused light spots are formed on the retina, the treatment area is sufficient, energy distribution is uniform, it is ensured that the irradiance is at the expected safety magnitude, and meanwhile the actual treatment effect is ensured.

A surgical model has a layer through which a surgical instrument is passed, such as a cornea or sclera. When the model is manufactured, a tunnel is pre-formed with a cross-sectional profile that does not include sharp bends which can lead to stress-risers, the latter tending to cause cracking of failure of the integrity of the layer. The pre-formed tunnel profile includes only radiused directional changes which tend not to lead to stress risers. The pre-formed tunnel can include tapered sidewalls which form a more narrow and flexible contact with a tool passed through the tunnel, reducing friction, improving mobility of the instrument, and enabling greater control of the pressure imparted upon the tool by the pre-formed tunnel.

Apparatus and methods are described for performing a capsulotomy procedure on a patient's eye. A diathermic capsulotomy tool includes a diathermic cutting element at its tip. An imaging system images the diathermic capsulotomy tool and the patient's eye. A computer processor drives a robotic unit to insert the diathermic capsulotomy tool into the patient's eye via an incision in a cornea of the patient's eye, such that the tip of the tool is disposed within the patient's eye and a remote center of motion location of the tool is disposed within the incision. The computer processor drives the robotic unit to move the cutting element in a circular motion while maintaining the remote center of motion location of the tool within the incision. Other applications are also described.

The invention discloses a center positioning system and method for a femtosecond laser ophthalmic corneal refraction operation, and relates to the technical field of image processing. The method comprises the following steps of S1, performing multi-source data synchronous acquisition on eyeballs of a patient before an operation; s2, fusing and preprocessing the collected multi-source data; s3, establishing an eyeball dynamics method, outputting six-degree-of-freedom position data in real time, and predicting the position of a laser action point; s4, dynamically adjusting the dual coordinate system according to the cornea; s5, constructing a real-time feedback system, and realizing closed-loop control, safety boundary control and a fault-tolerant mechanism; and S6, generating parameters of an operation process, constructing a four-dimensional cutting model, and performing path planning of the laser model. According to the method, the OCT, the Placido ring and the iris vein composite features are combined, the positioning precision is improved, Kalman filtering and neural network prediction compensation are utilized, eyeball movement is tracked in real time, and the accuracy of operation pupil positioning is improved.

The present invention relates to an eye tracking system (100). The system comprises at least one projection means (3) adapted to project a light beam (4) on a predetermined area of a cornea (2) of an eye (1). The system further comprises at least one optical sensor (6) capable of detecting reflected light (5) from the eye (1) and determining the location of detection thereon. The reflected light (5) from the eye (1) comprises at least one, preferably two, specular reflection, preferably at least a first Purkinje reflection (P1), more preferably at least a first Purkinje reflection (P1) and a fourth Purkinje reflection (P4). The system (100) is adapted to calculate the lateral and / or angular translation of the eye (1), or the change thereof, based on the location of detection and / or the displacement thereof.