The invention relates to a pre-compensation flexible assembling and adjusting mechanism of a large-
diameter transmission reflector. The pre-compensation flexible assembling and adjusting mechanism comprises the large-
diameter transmission reflector, a glue joint mandrel, an isolation telecentric flexible hinge, an isolation plate, a hooke flexible hinge, an adjusting flexible
branch chain, an anti-rotation flexible
branch chain, a back plate and a driving
assembly. The large-aperture transmission reflector is provided with three blind holes for glue joint, and is connected with the isolation plate through three groups of glue joint mandrels and isolation telecentric flexible hinges, so that isolation of load deformation interference of the isolation plate is realized; the driving ends of the two adjusting flexible
branch chains are correspondingly connected with two driving assemblies installed on the back plate, and the connecting ends of the adjusting flexible branch chains are connected with the isolation plate. One ends of the Hooke flexible hinges and the anti-rotation flexible branch chains are connected with the isolation plate, and the other ends are connected with the back plate; the device has the advantages of being simple in structural form, stable in movement and high in precision, meanwhile, the return clearance caused by
axial load reversing under heavy loads can be avoided, the additional
surface shape caused by assembling and adjusting stress is effectively isolated, and the additional
surface shape caused by gravity is compensated.