9949results about "Suture equipments" patented technology

A tissue repair guide includes a handle and a drill guide. The drill guide may include a channel. The drill guide may be locked in place using a securement component, for example a spring-loaded cap.

The invention relates to a high-activity recombinant XVII type collagen as well as a rapid preparation method and application thereof, and belongs to the technical field of bioengineering. The amino acid sequence of the high-activity recombinant XVII type collagen is as shown in SEQ ID NO. 1, and the nucleotide sequence of the high-activity recombinant XVII type collagen is as shown in SEQ ID NO. 2. The invention also provides a preparation method and application of the recombinant XVII type collagen. The high-activity recombinant XVII type collagen has good biological activity, has good effects of promoting cell adhesion, cell proliferation and cell migration, and can be compounded with other proteins to form raw materials of tissue engineering products, cosmetics, health care products or medicines. The high-activity recombinant XVII type collagen gene is integrated to different positions of a yeast genome through three different vectors, and the copy number of a target gene is increased, so that the expression quantity of the recombinant XVII type collagen is remarkably increased, and the yield of the high-activity recombinant XVII type collagen is effectively increased.

The invention discloses a separated modular anchor implantation system with a line, and relates to the technical field of medical apparatuses and instruments. The separated modular suture anchor implanting system comprises an inserter and a storage box, the inserter comprises an insertion rod, and an insertion part is arranged at the head of the insertion rod. An anchor and a suture line are stored in the storage box, an inlet and an outlet are formed in the two ends of the storage box respectively, and the insertion rod can be inserted into the storage box through the inlet, so that the insertion part is connected with the anchor in an inserted mode, the anchor is pushed out of the outlet, and the assembly of the inserter and the anchor is completed; after the anchor nail is implanted by the inserter, the insertion part and the anchor nail can be disconnected and the suture line can be directly withdrawn by moving the inserter in the direction opposite to the implanting direction without being removed by a doctor, so that independent storage of the anchor nail and the suture line is realized, and meanwhile, free assembly of the anchor nail and the inserter is realized; due to the modular structural design, the anchor can be selected and matched according to actual operation requirements, the inserter can be repeatedly used, waste of medical resources is reduced, and environmental protection is facilitated.

Implants, implant systems, and methods for treatment of mitral valve regurgitation and other valve diseases generally include a coaptation assist body which remains within the blood flow path as the leaflets of the valve move, the valve bodies often being relatively thin, elongate (along the blood flow path), and / or conformable structures which extend laterally from commissure to commissure, allowing the native leaflets to engage and seal against the large, opposed surfaces on either side of the valve body during the heart cycle phase when the ventricle contracts to empty that chamber of blood, and allows blood to pass around the valve body so that blood flows from the atrium to the ventricle during the filling phase of the heart cycle. Separate deployment of independent anchors near each of the commissures may facilitate positioning and support of an exemplary triangular valve body, with a third anchor being deployed in the ventricle. An outer surface of the valve body may accommodate tissue ingrowth or endothelialization, while a fluid-absorbing matrix can swell after introduction into the heart. The valve body shape may be selected after an anchor has been deployed, and catheter-based deployment systems may have a desirable low profile.

The invention provides a recombinant humanized III-type collagen with a triple helix structure and preparation and application thereof, and belongs to the technical field of protein engineering, the amino acid sequence of the recombinant humanized III-type collagen comprises n core units, n is an integer of 1 or greater than 1, and the amino acid sequence of each core unit is as shown in SEQ ID NO: 1; the invention also provides a construction method of the expression system and a preparation method of the recombinant humanized III-type collagen. The invention also provides practical industrial application according to the characteristics of the protein. The recombinant humanized III-type collagen provided by the invention is high in purity, good in stability and high in biological activity, and experiments show that the recombinant humanized III-type collagen has various biological activities of promoting cell proliferation and migration and the like.

The invention discloses an endoscope with a built-in grabbing mechanism, and relates to the technical field of medical instruments. According to the technical scheme, the device comprises a clamp assembly, a driving outer pipe and a driving inner wire; the grabbing mechanism further comprises a grabbing mechanism shell, a first moving seat and a second moving seat, wherein the first moving seat and the second moving seat are arranged in the grabbing mechanism shell. The near end of the driving outer tube is connected with the first moving seat, and the near end of the driving inner wire is connected with the second moving seat; when the second moving seat is fixed relative to the grabbing mechanism shell, the first moving seat moves towards the far end direction relative to the grabbing mechanism shell so as to control the clamp assembly to execute the clamping action. According to the invention, the clamping action is carried out while forward extension is carried out, so that high-precision operation is facilitated, and tissues can be accurately clamped; and moreover, the grabbing mechanism is integrated in the endoscope handle, so that accurate single-hand control is facilitated, meanwhile, the clamping action is controlled in a button mode, the human engineering is met, and operation is convenient.

A knotless tissue repair construct is disclosed herein. The construct includes a soft anchor body, with a proximal end, a distal end, and a longitudinal axis extending therebetween. The construct also includes a repair suture fixedly coupled to the anchor body. The construct also includes a transfer suture interwoven repeatedly through and along the anchor body defining a transfer path. Tension on at least one of the repair suture and transfer suture may deploy the anchor body. A transfer suture first end may transfer the repair suture through the anchor body to form a repair loop that may knotless lock the tissue repair construct.

A multiple pass self-cinching suture construct includes a strand of suture material. A fixed loop is formed at one end, and an adjustable loop is formed at the opposite end. A self-cinching section is disposed between the fixed loop and the adjustable loop. The self-cinching section includes a first pass of a tag end axially through the interior of the self-cinching section to form the fixed loop. The opposite tag end passes axially through the interior of two co-axial suture segments inside the self-cinching section, forming an adjustable loop. As the adjustable loop tag end is pulled, tension is applied and the self-cinching section constricts to maintain tension. In some embodiments, the self-cinching section includes at least four segments of the strand of suture material co-axially aligned along the self-cinching section.

The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation enhancement element for implantation across the valve; a system including the coaptation enhancement element and anchors for implantation; a system including the coaptation enhancement element, catheter and driver; and a method for transcatheter implantation of a coaptation element across a heart valve.

A method and apparatus for coupling a soft tissue implant into a locking cavity formed within a bone is disclosed. The apparatus includes a member to pull the soft tissue implant into a femoral tunnel. The member includes a suture having first and second ends which are passed through first and second openings associated with the longitudinal passage to form a pair of loops. Portions of the suture lay parallel to each other within the suture. Application of tension onto the suture construction causes retraction of the soft tissue implant into the femoral tunnel.

A suturing device comprising an elongated member including a cavity formed in a surface thereof, a needle passage, and a vacuum port. When the elongated member is inserted into a body including tissue and a vacuum is applied to the cavity, the tissue is captured by the cavity. A needle pusher is operable to move a needle having a sutured attached thereto through the tissue until a first end of the needle is captured by a needle capturing assembly. A clamp coupled to the elongated member is used to extract the needle from the needle capturing assembly and reposition the needle with suture attached to be re-engaged by the needle pusher. The cavity may include a plurality of cavity portions for capturing multiple contiguous portions of the tissue such that a single pass of the needle and the suture results in the suturing of the multiple portions of the tissue.

A suture needle guide tube includes a tube body and a suture needle guide. The tube body includes an internal axial channel for arranging a handling tube and a plurality of suture needle passing paths located in different positions for guiding a suture needle to pass therethrough. The suture needle guide includes a plurality of suture needle guide channels. Each suture needle guide channel communicates with the corresponding suture needle passing path to guide the suture needle out of the suture needle guide channel, through the suture needle passing path, and into an inner cavity and to allow the suture needle to exit with a suture.

A suture passing drill for passing suture through bone. The suture passing drill includes a proximal end and a distal end with an elongated shaft extending therebetween. The elongated shaft has first portion with a first diameter. The drill also includes a wire loop extending from the proximal end of the elongated shaft and a drill tip at the distal end of the elongated shaft. The elongated shaft has a narrow portion with a second diameter, which is smaller than the first diameter. The narrow portion is positioned proximally adjacent relative to the drill tip. The narrow portion is preferably created through coining. Coining prevents the need for machining the outer diameter (or surface) of the elongated shaft proximal to the drill tip in order to create a larger drill tip. The larger drill tip of the suture passing drill allows for passage of the entire drill through the bone hole.

The invention discloses an absorbable suture line for surgical suture and a preparation method thereof, and relates to the technical field of medical materials. The absorbable suture line for surgical suture is prepared from the following raw materials in parts by weight: 50 to 65 parts of polylactic acid, 15 to 20 parts of polyglycolic acid, 3 to 5 parts of sodium carboxymethyl cellulose, 3 to 8 parts of a toughening agent, 3 to 6 parts of an antibacterial agent, 0.3 to 0.8 part of a lubricating agent, 1 to 2 parts of sodium hyaluronate and 5 to 10 parts of polyvinyl alcohol. The toughening agent is obtained by reacting hydroxyethyl acrylate with ethylenediamine to generate a four-arm compound and then reacting with 6-caprolactone and DL-lactide. The absorbable suture line for surgical suture prepared by the invention has excellent tensile property and antibacterial property, and can meet the application requirements of clinical medical treatment.

The invention provides a robot-assisted wound suturing method and system based on artificial intelligence, and relates to the technical field of artificial intelligence, and the robot-assisted wound suturing method comprises the steps: obtaining multi-modal perception data of a wound area, constructing multi-modal three-dimensional representation of a wound, and determining a plurality of suturing points based on the multi-modal three-dimensional representation of the wound; for each suture point, calculating a candidate suture point, and for the adjacent suture points, generating a needle tip track of a needle tip in the wound, and sampling on the needle tip track to obtain a suture scheme adapted to the wound form and the tissue attribute; based on the obtained stitching scheme, an optimal control sequence of the stitching robot is obtained, meanwhile, a robust compensation control law is constructed through coordinate transformation and a feedback control law, and the optimal control sequence and the robust compensation control law are integrated into a stitching robot real-time control system; the output of a real-time control system of the suturing robot is converted into an actuator control instruction, and the suturing robot is controlled to assist in wound suturing.

An orthopedic tool includes a main body and a reference member. The reference member may be configured to engage an anatomical feature of a patient, such as the patient's bone. The angle of the reference member may be adjusted using a knob.

A suture locking apparatus is disclose that includes: a suture lock assembly, and a device for actuating and deploying the suture lock assembly, where the device includes: a catheter tube having a proximal end and a distal end; and a pusher wire positioned within the catheter tube for delivering a first pushing force to the suture locking tab for inserting the suture locking tab into the suture locking housing.

An orthopedic tool includes a main body and a reference member. The reference member may be configured to engage an anatomical feature of a patient, such as the patient's bone. The angle of the reference member may be adjusted using a knob.

The invention relates to a knotting-free medical repair assembly and a pre-configuration method thereof, and the medical repair assembly comprises an anchoring part which is provided with a first end part and a second end part; the suture line at least penetrates through a part of the anchoring part, the suture line is provided with a cable eye, and the cable eye is located on one side of the first end part and / or the second end part in the extending direction of the suture line; and at least one traction member partially passing through the eyelet of the suture line. According to the medical repair assembly, the rope eye is located outside the anchoring piece in the using state, the resistance for pulling the suture line when the annular shape is tightened can be reduced, the closing degree of the annular shape can be accurately controlled, and furthermore, the two ends of the suture line can be pulled at the same time or alternately, so that the tension of different parts can be adjusted, controlled and balanced; and negative effects caused by excessive concentration of local stress are avoided.

The invention discloses an anti-degradation recombinant collagen as well as a preparation method and application thereof, and belongs to the technical field of collagen and bioengineering. According to the invention, full-length or partial genes of natural collagen in a human body are selected for certain optimization combination, a collagen amino acid sequence with strong stability and high biological activity is designed, and the amino acid sequence is completely consistent with a sequence of a corresponding region of the natural collagen in theory, and has relatively low immunogenicity; and the collagen has typical biological functions of human body collagen. The recombinant collagen prepared by the invention has excellent stability, biological activity and safety.

The invention discloses a flexible mechanical arm driving system for minimally invasive interventional surgery, a flexible mechanical arm comprises a hollow first sleeve assembly which is coaxially configured, the first sleeve assembly comprises an inner tube and an outer tube, the inner tube and the outer tube are thin-walled tubes, the inner tube is arranged in the outer tube in a penetrating manner, and the inner tube and the outer tube are fixedly connected at the far end part; the inner tube and the outer tube are each provided with a straight tube section at the near end and a deformation section at the far end, and the deformation sections can be bent and deformed when the inner tube is pushed / pulled. The driving system comprises an instrument assembly and a driving module assembly; a driving driven module is arranged in the instrument assembly, and the flexible mechanical arm is connected with the driving driven module; a driving driving module and a PCB control board are arranged in the driving module assembly, the driving driving module is in transmission connection with the driving driven module, and the driving module assembly is used for driving the flexible mechanical arm to do linear, rotating and bending movement. The driving device is used for driving the coaxial antagonism tubular flexible mechanical arm to achieve bending, rotating and linear motion, full-automatic control can be achieved, and the control accuracy and safety are high.

A suture passer for passing a suture across a tissue. The suture passer can include an upper jaw member and a lower jaw member extending from an elongate member. The lower jaw member can have a curved portion that offsets a straight portion of the lower jaw member from the central axis of the elongate member. The lower jaw member can house a needle that can be deployed across a tissue to pass a suture across.

A suture assembly comprises a suture anchor, a repair suture, and a shuttle suture. Each suture has a looped end and a tail end. The tail end of the repair suture and the looped end of the shuttle suture extend out one side of the proximal end of the anchor, while the looped end of the repair suture and the tail end of the shuttle suture extend out the opposite side of the anchor. The tail of the repair suture may have a proximal portion which is thicker than its end portion. The suture anchor may include a proximal bore receiving the repair suture and a distal bore receiving the shuttle suture. The distal bore may have a rear opening having a diameter approximately equal to the diameter of the proximal portion of the suture and a front opening that is larger than the rear opening.

Exemplary methods and systems can be provided for resurfacing of skin that include formation of a plurality of small holes, e.g., having widths greater than about 0.2 mm and less than about 0.7 mm or 0.5 mm, using a mechanical apparatus. Compressive and / or tensile forces can then be applied to the treated region of skin as the damage heals to facilitate hole closure, and provide enhanced and / or directional shrinkage of the treated skin area.

Provided is a suture tightening device, including: a first thread take-up wheel, a second thread take-up wheel, and a thread gear support detachably connected to an endoscope handle, wherein the first thread take-up wheel is arranged at a space from the second thread take-up wheel, and the first thread take-up wheel and the second thread take-up wheel are separately in rotatable connection to the thread gear support.

The invention relates to the technical field of medical apparatus and instruments, and discloses a multi-degree-of-freedom flexible arthroscope bite forceps which comprise a handle shell, a rigid connecting pipe is fixedly connected to the front end of the handle shell, and a driving handle is hinged to the rear end of the handle shell; the bite forceps assembly comprises a flexible pipe and a bite forceps head, one end of the flexible pipe is connected with the rigid connecting pipe, the bite forceps head is detachably connected with the other end of the flexible pipe, and the driving handle is connected with the bite forceps head and is configured to enable the bite forceps head to be meshed when the driving handle is pinched; the control assembly comprises two control pieces, the two control pieces are arranged in the handle shell respectively, the top ends of the two control pieces stretch out of the handle shell to be fixedly connected with a rotary knob, and the two control pieces are connected with the bite forceps head respectively and are configured to drive the bite forceps head to conduct vertical / transverse angle adjustment when the rotary knob is manually screwed. Multi-degree-of-freedom rotation operation of the arthroscope bite forceps is achieved, the operation flexibility of surgeons is guaranteed, and the operation efficiency is improved.

A suture button system for fixing a syndesmotic injury comprises a flexible fixation implant and an inserter device used to deploy the implant across bones. The flexible fixation implant typically comprises a flexible connector and two suture buttons which interface with the bone surface or a bone plate or washer. The flexible connector comprises a plurality of suture strands. The buttons typically have a feature which allows them to interface with an instrument used to deploy the implant across the two bones. The inserter device is configured to interface with the flexible fixation implant and to position it across bones through a pre-drilled bone tunnel. The inserter device may comprise an cannulated insertion rod and a handle.

The invention discloses a bio-based polyamide elastomer as well as a preparation method and application thereof. A hard segment domain of the bio-based polyamide elastomer is formed by polymerizing aliphatic straight-chain dibasic acid and aliphatic straight-chain diamine, and a soft segment domain of the bio-based polyamide elastomer is formed by polymerizing aliphatic straight-chain dibasic acid and polyether amine. According to the preparation method, the polyamide salt solution and the polyether amine salt solution are firstly prepared respectively, then the bio-based polyamide elastomer with the hard segment domains and the soft segment domains being alternately blocked is obtained through reaction copolymerization of the two salt solutions, and through control of the soft segment domains, the bio-based polyamide elastomer has good strength and flexibility and good biocompatibility, and can be used for preparing the bio-based polyamide elastomer with the hard segment domains and the soft segment domains being alternately blocked. The problems that an existing elastomer is low in strength, poor in biocompatibility and the like are solved.

Embodiments described herein relate to an implant delivery system for delivering an implant for reducing heart valve regurgitation. The implant delivery system may include an implant catheter disposed in an inner lumen of a guide catheter. The implant catheter may include one or more hypotubes disposed therein, each hypotube configured to receive an elongate member such as a braided tether. A distal end of the implant catheter may be coupled to an implant holder configured to receive the implant. The implant holder may define one or more channels, each channel configured to receive a portion of a respective elongate member. The elongate members configured to couple the implant to the implant holder and transition the implant between configurations. The implant configured to be disposed around a portion of a leaflet of a heart valve to improve coaptation of the heart valve.