The invention provides an
electrode device and method for promoting
plasma active particle tissue
permeation, a first
electrode, an insulating layer and a second
electrode are sequentially arranged from inside to outside, the first electrode sequentially comprises a needle tube, a slot, a cylinder and a needle tip from top to bottom, the slot of the first electrode and the needle tube part are wrapped by the insulating layer, holes are uniformly formed in the front section of the insulating layer, and the needle tip is arranged in the cylinder. The rear end of the first electrode needle tube is connected with the positive electrode of the
pulse power supply, and the rear end of the second electrode is connected with the negative electrode of the
pulse power supply. The front end of the electrode can enter the deep part of tissue,
plasma can directly act on target cells, the pulsed
electric field acts on the
body tissue and
plasma active particles at the same time, and the penetrating power of the
active particles can be improved from the two aspects of the characteristics of the
active particles and improvement of tissue permeability; the matching mode of the pulsed
electric field and the plasma can be adjusted, it is ensured that
electroporation happens to the tissue within a recoverable range, the normal function of the tissue is not affected, and meanwhile
permeation of active particles in the tissue is promoted.