58 results about "Peritoneal cavity" patented technology

The invention relates to an automatic peritoneal dialysis machine auxiliary system capable of preventing peritoneal protein from being lost, and belongs to the technical field of peritoneal dialysis. By arranging the auxiliary system comprising a hollow fiber membrane filter, peritoneal drainage liquid is guided into the hollow fiber membrane filter in the drainage stage; the protein is intercepted by utilizing the semi-permeable membrane characteristic, and small molecule metabolic wastes penetrate through the semi-permeable membrane characteristic to form a filtrate rich in the protein; and then the feedback pump speed is dynamically adjusted through a control system based on a signal of a flow sensor, so that the feedback process of the protein liquid is stably synchronized with drainage, liquid injection and staying stages of the automatic peritoneal dialysis machine, online recovery and safe feedback of protein are realized, and the problem that the protein liquid flows back to the treatment cycle of the automatic peritoneal dialysis machine is solved on the premise that the treatment cycle is coordinated with the treatment cycle of the automatic peritoneal dialysis machine. Protein in peritoneal drainage liquid is continuously and selectively recovered and safely returned, so that the problem of protein trophism loss of long-term peritoneal dialysis patients is directly reduced.

The invention relates to the technical field of medical apparatus and instruments, and discloses an abdominal cavity wound PRP treatment drainage tube visual observation system, which comprises an intelligent imaging module used for collecting multispectral image data of an abdominal cavity wound; the multi-mode sensing module is used for synchronously acquiring various physiological parameter data of a wound surface target area; the spatial memory mapping module is used for establishing a three-dimensional spatial memory model of the wound surface through dynamic light field reconstruction according to the multispectral image data; and a treatment decision analysis module. And the treatment decision analysis module performs semantic segmentation on the three-dimensional space memory model to identify a wound area, fuses the physiological parameter data, and calculates and outputs an optimal PRP treatment site three-dimensional coordinate through a preset optimization algorithm. According to the method, the three-dimensional shape, the spectral characteristics and the multi-dimensional physiological parameters of the wound surface are deeply fused in the data level, so that objective and quantitative decision-making of the PRP treatment site is realized, and the treatment accuracy is improved.

The present disclosure generally relates to systems and methods of use for draining cerebrospinal fluid (CSF) from a brain or a spinal canal in a subject, for example, to treat hydrocephalus or other conditions. In some embodiments, the disclosure relates to a device comprising a flow controller positioned within a conduit that allows CSF to flow through the conduit from a first end to a second end. This may allow the CSF to drain, for example, from an intradural space (such as a thecal sac) into, for example, a paraspinal space, paraspinal vein or other venous space, or peritoneal cavity. A variety of methods may be used to hold or anchor the device in place, for example, an expansion apparatus. In some embodiments, the device can be implanted percutaneously at a location along or within a subject's spinal column, thus reducing the need for surgery, general anesthesia, and hospitalizations.

A leak detecting apparatus (1) for detecting a leak and determining the size of the leak in a suture repaired site (5) of a hollow organ (3), for example, a stomach, in a cavity (7), for example, the peritoneal cavity of a subject comprises a first insufflator (12) for insufflating the hollow organ (3) with a first gas, and a second insufflator (14) for insufflating the cavity (7) with a second gas. A gas detector (18) is provided for detecting the concentration of the first gas in gases exhausted from the cavity (7) through a communicating conduit (35). A flow meter (25) monitors the flow rate of the first gas to the hollow organ (3). First and second pressure sensors (15) and (16) monitor the static pressure of the first and second gases in the hollow organ (3) and the cavity (7), respectively. The apparatus (1) is operable in a first mode and a second mode. In both the first and second modes of operation a microprocessor (50) controls the second insufflator (14) for maintaining the pressure in the cavity (7) at a relatively low predefined pressure, and the first insufflator (12) for maintaining a constant predefined pressure differential between the pressures in the hollow organ (3) and the cavity (7) of approximately 7 mmHg. In the first mode the microprocessor (50) determines the size of the leak as a function of the pressure differential and the concentration of the first gas in the exhaust gases. In the second mode of operation the microprocessor (50) determines the size of the leak as a function of the pressure differential and the flow rate of the first gas to the hollow organ (3) with the hollow organ (3) sealed apart from the sutured site (5).

The utility model relates to an automatic flue gas removing abdominal machine, which is characterized in that a main body is a pneumoperitoneum machine for establishing and maintaining pneumoperitoneum; the pneumoperitoneum machine comprises an air inlet channel, and the two ends of the air inlet channel are connected with an air source and an abdominal cavity respectively. One end of the exhaust channel is communicated with the abdominal cavity, and a smoke removal pump and an electromagnetic valve are sequentially arranged in the airflow flowing direction; the micro-control unit is provided with a digital communication interface used for being connected with an endoscope camera system; wherein a branch pipe communicated with the exhaust passage is arranged at the air inlet end of the smoke removal pump, the other end of the branch pipe is communicated with the exhaust passage at the air outlet end of the smoke removal pump, and a speed regulating proportional valve is arranged on the branch pipe; and the micro-control unit is connected with the speed regulation proportional valve, the smoke removal pump and the electromagnetic valve. The smoke exhaust device has the advantages that the smoke exhaust device can adjust the size of smoke, adjust the gas displacement, ensure that the smoke is removed to the maximum extent with the minimum gas consumption, reduce the consumption of carbon dioxide gas and reduce the consumption cost of medical consumables.

A dialysis system having motor driven pressure estimation of fluid within a patient line is disclosed. A peritoneal dialysis (“PD”) system includes a fluid pump and a patient line that fluidly couples the fluid pump to an indwelling catheter leading into a patient's peritoneal cavity. The PD system also includes a motor driver that controls a motor of the fluid pump and transmits an output signal that is indicative of a load on the motor. The PD system further includes a machine learning algorithm that associates data related to output signals from motor drivers with known fluid pressures within patient lines. A processor of the PD system transmits an input signal to activate the motor driver, receives the output signal from the motor driver, and estimates a fluid pressure within the patient line by applying the data from the received output signal to the machine learning algorithm.

The utility model discloses a drainage tube pull-out post-operation dressing change component, including support rod and dressing, the support rod includes support section and handle, the dressing is wrapped in the support section, the dressing is bonded with the support section, the dressing includes cotton yarn layer and antibacterial coating. According to the dressing changing assembly after the drainage tube is pulled out, treatment can be conducted according to the recovery condition of a wound, dressing can stretch into the wound or even the peritoneum of the abdominal cavity through the supporting rod, the wound can be better sterilized and killed, and the wound can be better recovered.

The utility model discloses a kind of peritoneal cavity flushing drainage tube support frame, including liquid receiving disc and support pipe, liquid receiving disc is equipped with tray cavity, tray cavity upper surface is equipped with tray mouth, tray mouth is equipped with the fixed structure for fixing the position of existing peritoneal cavity drainage tube and existing negative pressure tube, peritoneal cavity drainage tube and negative pressure tube suture are disposed in tray mouth, so that suture place exudate falls in tray cavity, support pipe upper end is fixed in the lower surface of liquid receiving disc, support pipe lower end is equipped with base, base outside is equipped with hose, hose is communicated with tray cavity, existing drainage bag pagoda connector is inserted in hose, liquid in tray cavity flows to drainage bag by hose.The support frame of the utility model not only can fix the position of peritoneal cavity drainage tube and negative pressure tube, and raise drainage tube end, but also can collect peritoneal cavity drainage tube and negative pressure tube suture place exudate, avoid suture place exudate falling on bed surface and cause pollution, reduce the workload of medical staff arranging bed surface.

The invention discloses a pressurizing flushing device for hyperthermic intraperitoneal perfusion chemotherapy, and relates to the technical field of medical instruments. Comprising a puncture catheter and a multidirectional flow guide nozzle, the puncture catheter comprises a catheter body, multiple sets of supporting cavities are formed in the catheter body in the length direction, the supporting cavities are communicated through second air inlet channels, and the supporting cavities are of an arc-shaped structure; the end part of the guide pipe body is connected with a multidirectional flow guide nozzle; one end of the nozzle main body is connected with a drainage guide pipe; the drainage catheter is used for connecting a chemotherapy pump machine; the nozzle body comprises a sprayer and a connecting pipe. The other end of the connecting pipe is connected with the drainage catheter; a plurality of through holes are formed in the spray head; and a rotor is rotationally arranged in the connecting pipe. The catheter is prevented from being bent and collapsed under the action of external force such as extrusion of visceral organs in the abdominal cavity and body position change, and it is ensured that a liquid medicine conveying channel is smooth; in addition, the contact uniformity of the liquid medicine and the abdominal cavity wall, especially the peritoneal micro transfer focus, is obviously improved.

This invention belongs to the field of biomedical technology, specifically relating to a human-derived cell line for peritoneal metastasis of gastric cancer and its applications. The invention involves collecting ascites from gastric cancer patients and culturing it into organoids. These organoids are then transplanted subcutaneously into immunodeficient mice to form xenografts (PDOX). The transplanted organoids are digested and passaged in vitro to obtain a purified cell line. The primary isolated cell line is then inoculated into the peritoneal cavity of immunodeficient mice to induce the formation of metastatic ascites. Cells are extracted from the metastatic ascites and cultured again into organoids to construct human gastric cancer ascites cells, named BZGC. The cell line constructed in this invention has the ability to form 100% metastatic ascites in the mouse peritoneal cavity, fully simulating the entire process of ascites formation in gastric cancer peritoneal metastasis. The human-derived gastric cancer ascites cells described in this invention provide a stable, reliable, and highly clinically and pathologically similar in vitro and in vivo model for studying the mechanism of gastric cancer peritoneal metastasis, drug screening, and personalized treatment.

A peritoneal dialysis system includes (i) a fill container, and (ii) an energizing unit that removably accepts the fill container, the energizing unit including a sterilization source so configured and arranged relative to the fill container when accepted by the energizing unit to place fluid within the fill container in a physiologically safe condition for delivery to the peritoneal cavity of a patient.

This invention provides a peritoneal dialysis catheter repositioning device, comprising a catheter body, a sliding plug, a gas delivery device, and an external magnet. The catheter body is inserted into the peritoneal dialysis catheter. The sliding plug is slidably disposed within the catheter body. A plate-shaped internal magnet is embedded within the sliding plug; the magnetic poles of the internal magnet are perpendicular to the axis of the catheter body. The gas delivery device forces the sliding plug forward within the catheter body to the desired segment of the peritoneal dialysis catheter for adjustment. The external magnet attracts or repels the internal magnet, thereby adjusting the catheter segment to the set position. This invention can utilize the attractive force between the external magnet and the internal magnet to move a segment of the catheter outward, or utilize repulsive force to move the segment inward. Each adjustment is a localized adjustment of the peritoneal dialysis catheter's position, not only repositioning the catheter but also adjusting and repositioning the catheter's embedding shape within the peritoneal cavity.

The application discloses a peritoneal cavity drainage negative pressure adsorption device with detection function, and relates to the field of peritoneal cavity drainage adsorption devices. The application provides a peritoneal cavity drainage negative pressure adsorption device with detection function which can keep a puncture needle stable. The peritoneal cavity drainage negative pressure adsorption device with detection function comprises a U-shaped sliding frame, a sliding plate is slidably connected to the U-shaped sliding frame, symmetrical bases are fixedly connected to the U-shaped sliding frame, a supporting frame is slidably connected to the sliding plate, a puncture needle is arranged between the supporting frame and the sliding plate, an infrared sensor is installed on the supporting frame, a screw rod is fixedly connected to the supporting frame, and a nut is threadedly connected to the screw rod. The turbidity of ascitic fluid drawn out is detected by the infrared sensor, so that the optimal puncture position is determined. The fixing of the puncture needle is completed by the supporting frame, the screw rod and the nut, the discomfort of a patient caused by movement of the puncture needle during puncture can be reduced, and local serious bleeding caused by movement of the puncture needle is prevented.

A method of performing peritoneal dialysis (PD), the method comprising: delivering a PD fluid to the peritoneal cavity of a patient through a PD catheter; dwelling the PD fluid within the peritoneal cavity; and while dwelling the PD fluid, removing a biofilm from the PD catheter wall using a biofilm removing solution. The biofilm removing solution comprises: sodium citrate dihydrate; citric acid anhydrous; sodium lauryl sulfate; and water. In another aspect, a method for decontaminating a peritoneal dialysis (PD) catheter and removing a biofilm from the PD catheter and a transfer set, the method comprising: providing a biofilm removing solution; transferring the biofilm removing solution into a syringe; connecting the syringe to a transfer set of the PD catheter; and filling the transfer set and the PD catheter with the biofilm removing solution.

The invention discloses an application of an REV-ERB alpha agonist SR9009 in preparation of a medicine for preventing and treating thoracic aortic aneurysm and dissection. The invention provides an application of an REV-ERB alpha agonist SR9009 in preparation of a medicine for preventing and / or treating thoracic aortic aneurysm and dissection. The step of preventing and treating the TAAD comprises the substeps of reducing the incidence rate of the TAAD and relieving cavities and / or fractures of the middle-layer structure of the thoracic aorta. Through intraperitoneal injection of the SR9009 in a TAAD mouse model, the result shows that the SR9009 can significantly reduce BAPN-induced mouse thoracic aorta VSMC apoptosis and elastic fiber degradation, and improve the histopathologic change of TAAD; the blood pressure, the body weight and the blood fat level of the mouse are not obviously influenced by the administration of the SR9009, and the SR9009 has good safety, so that the SR9009 provided by the invention has a good clinical application prospect.

The invention discloses an automatic flow regulator for an abdominal cavity hyperthermic perfusion chemotherapy water outlet pipe, and relates to the technical field of chemotherapy equipment. The automatic flow regulator comprises a shell, a water outlet pipe containing groove is formed in the middle of the shell, a hinge is installed at an opening in one side of the water outlet pipe containing groove, the hinge is hinged to one end of a cover plate, and a fixing button is installed at the other end of the cover plate; the upper surface of the shell is provided with a display screen and keys, and the display screen and the keys are electrically connected with the controller; an adjustment execution assembly and a flow detection unit are further installed in the shell. The adjustment execution assembly and the flow detection unit are both electrically connected with the controller. According to the automatic flow regulator for the water outlet pipe for hyperthermic intraperitoneal perfusion chemotherapy, manual operation is replaced, automatic and real-time regulation of flow is achieved, and the regulation response time is short; the flow control precision is high, the in-vivo liquid amount is stabilized, and the curative effect stability of intraperitoneal hyperthermic perfusion chemotherapy is improved; the adaptability is good, and the medical risk is reduced through the safety alarm function; and existing perfusion equipment is compatible, and clinical popularization is facilitated.

The invention discloses an application of a BMAL1 activator ISX-9 in preparation of a medicine for preventing and treating thoracic aortic aneurysm and dissection. The invention provides an application of a BMAL1 activator ISX-9 in preparation of a medicine for preventing and / or treating thoracic aortic aneurysm and dissection. The step of preventing and treating the TAAD comprises the substeps of reducing the incidence rate of the TAAD and relieving cavities and / or fractures of the middle-layer structure of the thoracic aorta. According to the application disclosed by the invention, ISX-9 is subjected to intraperitoneal injection in a TAAD mouse model, and a result shows that the ISX-9 can be used for remarkably reducing BAPN-induced mouse thoracic aorta VSMC apoptosis and elastic fiber degradation and improving the histopathologic change of TAAD; the blood pressure, the body weight and the blood fat level of the mouse are not obviously influenced by the administration of the ISX-9, and the ISX-9 has good safety, so that the ISX-9 provided by the invention has a good clinical application prospect.

The puncture catheter is characterized in that the puncture catheter comprises a catheter body, a plurality of sets of supporting cavities are sequentially formed in the catheter body in the length direction, the supporting cavities are sequentially communicated through second air inlet channels, and each supporting cavity is of an arc-shaped structure; the catheter body is further provided with a first air inlet channel, the end of the first air inlet channel is connected with a blocking air bag, and the blocking air bag is arranged close to the end of the catheter body. Through the arrangement, gas is injected into the second gas inlet channel, so that each group of arc-shaped inner cavities are filled with the gas, and the structural strength and the extrusion resistance of the catheter body are effectively enhanced by utilizing the bending resistance characteristic of the arc-shaped structures and the supporting force after the gas is filled; the catheter is prevented from being bent and collapsed under the action of external force such as extrusion of visceral organs in the abdominal cavity, body position change and the like, a liquid medicine conveying channel is ensured to be smooth, and smooth proceeding of hyperthermic perfusion chemotherapy in the abdominal cavity is guaranteed.

The utility model relates to a retroperitoneal cavity dilatation balloon which comprises a balloon body which is not transmitted by X rays and has mark colors, an inflation device and a connecting pipe communicated with the balloon body and the inflation device, and the inflation device is used for controlling inflation gas flow and further controlling inflation capacity. The balloon and the connecting pipe are detachably connected in a sealed mode through a first connecting device, and the inflating device and the connecting pipe are detachably connected in a sealed mode through a second connecting device; a pressure relief device is fixed to the inflation device and used for relieving pressure when inflation pressure is larger than preset inflation pressure so as to prevent the balloon from being broken. And the inflating device and the pressure relief device are electrically connected with the controller. According to the retroperitoneal cavity expansion balloon, the inflation capacity and pressure of the balloon can be controlled, the balloon is prevented from being broken, and parts can be conveniently detached and replaced and fragments of the balloon can be conveniently found.

The invention belongs to the technical field of medical equipment, and particularly relates to an abdominal cavity hyperthermia perfusion pipeline dredging device which comprises a perfusion liquid medicine box, a flushing liquid box is fixedly connected to the upper surface of the perfusion liquid medicine box, a first heating pipe is fixedly connected to the inner bottom wall of the perfusion liquid medicine box, and a second heating pipe is fixedly embedded in the left side face of the flushing liquid box. A first temperature monitoring sensor is fixedly embedded in the front face of the liquid medicine filling box. Through the arrangement of the intraperitoneal hyperthermia perfusion tube, the flow sensor, the pressure sensor, the ultrasonic detection assembly, the central controller and the early warning alarm, flow and pressure data of perfusate in a pipeline can be collected in real time, and the position, the size and the form of blockages in the pipeline can be detected in a high-frequency ultrasonic mode; multi-sensor cooperative monitoring and high-frequency ultrasonic detection of the intraperitoneal hyperthermic infusion tube are achieved, suspected blockage signals can be captured in advance, timely alarm early warning and dredging treatment are carried out, treatment interruption caused by blockage deterioration is avoided, and the treatment effect is improved.

An automatic pump-based fluid management system, as described herein, includes an intercostal pump, typically an elastically flexible tube having an inlet and an outlet. The inlet is attached to a first tube that extends from the intercostal pump to a first region of the patient's body, such as a pleural cavity of the patient. The outlet is connected to a second tube that extends from the intercostal pump to a second region of the patient's body, such as a peritoneal cavity of the patient. In use, the intercostal pump is disposed between a first rib and a second rib of a patient. The intercostal pump is operated by being continuously compressed and decompressed between the first rib and the second rib as the patient breathes.

A test method determines at least one status parameter of an individual undergoing peritoneal dialysis. The status parameter(s) may include a transport property of the peritoneum, a tonicity, or a residual volume. The test method includes receiving first data indicative of a flow rate as a function of time of a treatment fluid into and out of a peritoneal cavity during a test procedure, and second data comprising measured data samples representing a concentration of one or more solutes in the treatment fluid at time points during the test procedure. The test method also includes computing, based on the first data and by use of a transport model for a peritoneal membrane, estimated data samples representing the concentration of the one or more solutes in the treatment fluid at the time points and determining the status parameter(s) as a function of the measured data samples and the estimated data samples.

The invention provides an automatic segmentation method and device for abdominal cavity free gas. The method comprises the following steps: acquiring a CT image to be segmented; extracting image features from the CT image; the image features comprise a plurality of channel features; inputting the image features into a preset segmentation network for segmentation processing to obtain a segmentation result output by the segmentation network; the segmentation network comprises a bilateral filter, an output module and a plurality of levels, and each level comprises a convolutional neural network, a Swin Transform module and a multi-scale feature fusion module. According to the scheme, the Swin Transformer module and the convolutional neural network are creatively fused, the multi-scale feature fusion module is introduced, more effective information is reserved through a more effective frequency-space feature fusion mechanism, the CT image segmentation performance is remarkably improved, and then accurate segmentation of the abdominal cavity free gas is achieved.

The application relates to a simulated pneumoperitoneum image generation method and device, computer equipment, a storage medium and a computer program product. The simulated pneumoperitoneum image generation method comprises the following steps: acquiring a peritoneal cavity image; determining a target region according to the peritoneal cavity image; performing simulated pneumoperitoneum fitting on the peritoneal cavity image according to the target region to determine a simulated pneumoperitoneum region; and determining a simulated pneumoperitoneum image according to the target region, the simulated pneumoperitoneum region and the peritoneal cavity image. The method can automatically divide the target region from the peritoneal cavity image, saves the time for manual labeling, enhances the automation degree in the simulated pneumoperitoneum image generation process, and adopts the simulated pneumoperitoneum fitting method to directly obtain the deformed peritoneal cavity state image after pneumoperitoneum on the image. Compared with the method for generating the peritoneal cavity state image by using a numerical simulation method, the image generation time is greatly saved.

A direct sodium removal (“DSR”) infusate regimen and methods of use are provided for removing sodium and reducing fluid overload in patients with severe renal dysfunction and / or heart failure, in which a patient has at least a first DSR session with a first DSR infusate having no or low sodium that is instilled into a patient's peritoneal cavity for a first dwell period to cause sodium and excess fluid to migrate to the patient's peritoneal cavity, and thereafter, the patient may undergo conventional dialysis to rebalance the patient's fluid and sodium levels.

The application discloses a peritoneal cavity chemotherapy perfusion dose-diffusion synergistic regulation method based on equipotential line search, comprising the following steps: S1, collecting peritoneal cavity three-dimensional image data, constructing a peritoneal cavity structure model, and identifying target / non-target tissues; S2, constructing a diffusion velocity field based on the structure model, and generating a three-dimensional diffusion equipotential line map using a fast marching method; S3, performing equipotential line search, identifying uncovered areas, diffusion mutation areas, and generating a candidate position set; S4, generating an optimized perfusion strategy based on the candidate set and a fitness function, and using a firework optimization algorithm; S5, generating control instructions and driving the perfusion system to execute the optimized perfusion scheme; S6, collecting feedback data in real time, reconstructing the equipotential line map, and performing steps S3 to S6 in a loop if the standard is not met. Through the construction of a dynamic individualized diffusion model and an intelligent optimization control system, the application realizes accurate delivery and real-time adjustment of peritoneal cavity chemotherapy drugs, and significantly improves drug efficacy coverage and treatment safety.

This invention discloses a method for establishing a model of oligoasthenospermia using trimethylamine N-oxide. The method involves injecting trimethylamine N-oxide into the peritoneal cavity of an animal to obtain the oligoasthenospermia model. This invention successfully established a mouse model of oligoasthenospermia by intraperitoneal injection of trimethylamine N-oxide (TMAO) into male mice. This provides new ideas and clues for in-depth research on the pathogenesis of oligoasthenospermia and for researchers studying male reproductive health. It also has significant scientific and medical value for understanding the pathogenesis of male infertility, developing new therapies, evaluating treatment effects, and promoting related clinical research.

The application relates to a peritoneal cavity free cell flushing and collecting device which comprises an operating body, a handle, a flushing pipe and a suction pipe; the flushing pipe is connected with the operating body, the suction pipe is arranged in the flushing pipe, the flushing pipe is not communicated with the suction pipe, the flushing pipe is connected with a flushing structure, the flushing structure is a pulse flushing structure; the suction pipe is connected with a suction structure in the operating body, the suction structure is a structure for sucking and collecting flushing liquid, a guide structure capable of adjusting a suction angle is arranged in the suction pipe; the flushing structure comprises a connecting pipe one connected with the flushing pipe, a water discharger capable of pulse water discharge, and a driving box connected with the water discharger.