4537 results about "Ultrafiltration" patented technology

The invention provides a zero-discharge treatment process for recycling production wastewater, and relates to the technical field of water treatment and recycling, and the zero-discharge treatment process comprises the following steps: S1, oxidizing and degrading COD through ozone and a Fenton reagent, and generating a flocculatable intermediate; s2, intercepting suspended matters by using a gradient aperture filter bed in a grading manner, and monitoring a dynamic membrane resistance coefficient delta Rm in real time to automatically trigger backwashing; s3, coupling an ultrafiltration reverse osmosis membrane to realize that the organic matter rejection rate eta is greater than or equal to 98%, and synchronously regulating and controlling flux and operation pressure by an online spectrometry; s4, regulating and controlling the current density by adopting a rotational flow electric flocculation reactor for directional crystallization to produce industrial salt with Cl <-> less than or equal to 50mg / L; and S5, based on the total dissolved solid recovery rate TR and the comprehensive energy consumption, establishing a multi-target optimization model for real-time parameter adjustment. According to the method, a membrane pollution early warning and backwashing dynamic response mechanism is constructed through cross-scale cooperative regulation and control of delta Rm and the retention rate eta, and a catalytic oxidation effect strengthening and electric crystallization parameter self-tuning technology is combined, so that the problem of cooperative optimization of high-salinity wastewater salt gradient separation and pollutant deep removal is solved.

The invention relates to the technical field of sewage treatment, in particular to a sewage treatment control process based on dynamic regulation and control of aeration and carbon source addition, which comprises the following steps: acquiring microbial metabolism heat change data in real time; biochemical treatment: monitoring the dielectric constant of a water body and the Reynolds number of sewage flow in real time, and constructing a multi-parameter coupling regulation and control model and dynamically regulating and controlling the aeration rate in combination with microbial metabolism heat change data obtained in the pretreatment step; accurately adding the carbon source according to a calculation result of the carbon source demand prediction model; sewage subjected to biochemical treatment is subjected to ultrafiltration through a nanofiber membrane and then subjected to combined disinfection treatment through ultraviolet rays and ozone, treatment parameters are regulated and controlled in real time according to the membrane flux attenuation trend in the treatment process, and dynamic and accurate control over sewage treatment is achieved. According to the method, the problem of energy consumption waste caused by excessive aeration or low degradation efficiency caused by insufficient aeration in a traditional process is solved, and accurate matching of dissolved oxygen supply and microbial requirements is realized.

The invention provides a virus-removing ultrafiltration membrane and a preparation method thereof, and belongs to the technical field of membrane separation. According to the preparation method of the ultrafiltration membrane, a hydrophilic polymer and a bulk polymer are blended to prepare a membrane casting solution, the ultrafiltration membrane is prepared on the basis of a double-layer homogeneous compounding method and a phase inversion method, and the obtained integrated ultrafiltration membrane comprises a separation layer with a compact skin layer and a pre-filtration supporting layer with a complete sponge structure, and provides high mechanical strength and toughness at the same time; the separation layer and the supporting layer form a hourglass-shaped structure with effective aperture continuously changing in a gradient mode, and no obvious interface or layering phenomenon exists. The ultra-filtration membrane is clear in gradient structure, the upper surface is loose, the lower surface is compact, the structures are fused more tightly, no obvious interface exists, the filtration resistance is reduced, and the protein permeability is improved. And the flux and the maximum treatment volume are improved and the treatment time is shortened while the relatively high virus rejection rate and the relatively low protein adsorption capacity are maintained.

The invention discloses preparation and application of antioxidative, anti-inflammatory and hypoglycemic lactoferrin peptide, and belongs to the field of food science and nutriology. According to the invention, lactoferrin is used as a raw material, hydrolysis is carried out by using a composite enzymatic hydrolysis method, and the molecular weight is obtained by ultrafiltration; the preparation method comprises the following steps: preparing a component of antioxidant, anti-inflammatory and hypoglycemic peptide from the active peptide YLSW (Tyr-Leu-Ser-Trp), carrying out freeze drying on the component to obtain peptide powder rich in antioxidant, anti-inflammatory and hypoglycemic peptides, identifying peptide fragments contained in the peptide powder by utilizing an LC-MS / MS technology, and screening out the active peptide YLSW (Tyr-Leu-Ser-Trp) with antioxidant, anti-inflammatory and hypoglycemic triple functions. The active peptide is added into the product to obtain the antioxidant, anti-inflammatory and hypoglycemic functional product.

The invention discloses a desalting membrane as well as a preparation method and application thereof, and relates to the technical field of membrane separation. The desalting membrane comprises a porous ultrafiltration base membrane and a functional layer formed on the surface of the porous ultrafiltration base membrane; the functional layer is formed by copolymerizing and cross-linking a polyamine monomer, a zwitterionic multi-element hydroxyl monomer and an acyl chloride monomer through an interfacial polymerization reaction. The preparation method comprises the following steps: providing the porous ultrafiltration base membrane; coating the surface of the porous ultrafiltration base membrane with an alkaline water-phase solution containing a polyamine monomer and a zwitterionic multi-hydroxyl monomer to form a water-phase solution layer; coating an oil-phase solution containing an acyl chloride monomer on the surface of the water-phase solution layer to form a functional layer; and performing heat treatment. The invention also provides application of the desalination membrane in any one of seawater desalination, brackish water desalination, wastewater treatment and material separation and concentration. According to the invention, zwitter-ion-based multi-hydroxyl monomers are introduced into water-phase monomers to participate in interfacial polymerization, and a super-hydrophilic nano-channel is constructed in a separation layer, so that the water flux and the desalination rate of the membrane are remarkably improved.

The invention discloses an intelligent detection and dynamic early warning system based on machine learning and multi-source data fusion, which relates to the technical field of membrane separation process monitoring and consists of a data acquisition and preprocessing part, a physical model and data driving model part, a dynamic weight fusion and self-adaptive mechanism part and a man-machine interaction and alarm part. According to the system, parameters such as membrane flux, transmembrane pressure difference, solution concentration, temperature, water inlet flow and operation pressure are collected, an improved XGBoost machine learning model is combined, and a comprehensive pollution index is constructed to quantify the membrane pollution degree; the model realizes double analysis of a pollution mechanism and a data rule through feature engineering. The system supports full-closed-loop management from minute-level early warning to hour-level cleaning decision making, the threshold value is dynamically adjusted through Bayesian optimization, the generalization and anti-interference capacity of the system are remarkably improved, and the system is suitable for intelligent operation and maintenance of membrane separation processes such as reverse osmosis and ultrafiltration.

The invention discloses a ginseng exosome, an extraction method thereof and application of the ginseng exosome in preparation of anti-photoaging skin care products, and belongs to the technical field of biological medicines. In order to solve the technical blank of ginseng exosomes in the aspect of light aging resistance in the prior art and solve the technical problems of complicated steps, long time consumption and small treatment capacity of exosome extraction by an ultracentrifugation method in the prior art, the invention provides an extraction method of ginseng exosomes. Therefore, the extraction rate of the ginseng exosome is improved, the treatment steps are simplified, the time is saved, and the purpose of producing the ginseng exosome in a large scale is achieved. The ginseng exosome obtained through the extraction method can be applied to preparation of anti-photoaging skin care products, and clinical application of the exosome is achieved.

The invention discloses an anti-EV71 virus activity buthus martensii toxin polypeptide as well as a preparation method and application thereof, and belongs to the technical field of antiviral preparations. A scorpion tail electricity-saving stimulation method is adopted to obtain crude scorpion venom, and centrifugation and freeze drying are performed to obtain scorpion venom freeze-dried powder; dissolving the scorpion toxin freeze-dried powder, filtering, removing sediment, carrying out ultrafiltration centrifugation, and separating to obtain the anti-EV71 virus activity scorpion toxin polypeptide. According to the present invention, the scorpion martensii toxin polypeptides S-I (lt; 3kDa) and S-II (3-10 kDa) obtained from the scorpion martensii have good EV71 virus resistance; under the same concentration, the relative molecular mass is lt; compared with the prior art, the scorpion margaritae toxin polypeptide with the molecular weight of 3kDa has better anti-EV71 virus activity, has no toxic effect on cells, has the potential of being used as an anti-EV71 virus drug, and provides a theoretical basis for biomedical research and clinical application of the scorpion margaritae toxin polypeptide.

The invention discloses an integrated process for cooperative treatment and up-to-standard discharge of industrial wastewater and domestic wastewater of a power plant, and relates to the field of cooperative treatment of wastewater and sewage, and the integrated process comprises the following steps: configuring a raw water collection system, setting a raw water source, configuring a multi-stage filtration and heating pretreatment process, configuring an ultrafiltration membrane system, and setting a fine filtration path. A first-stage reverse osmosis system is configured, reverse osmosis parameters are set, a second-stage reverse osmosis system is configured, a low-conductivity water treatment path is set, a mixed ion exchanger is configured, a desalted water output path is set, a standby pool body is set, and the adjusting capacity is set. A raw water collecting system, a multi-stage filtering and heating pretreatment process, an ultrafiltration membrane system, a first-stage reverse osmosis system, a second-stage reverse osmosis system, a mixed ion exchanger and a standby pool body are sequentially arranged in the process. The problems of unstable effluent quality, insufficient deep desalination capability and poor emergency regulation capability in a traditional power plant wastewater treatment mode can be effectively solved.

The invention particularly relates to printing and dyeing wastewater advanced treatment equipment and a method thereof. The equipment comprises a pretreatment unit, an electrolysis unit, a pH regulation unit, a post-treatment unit and a comprehensive monitoring unit, the pretreatment unit comprises a physical filtering device and an advanced oxidation pretreatment device and is used for removing suspended solids and macromolecular organic matters; the electrolysis unit is provided with a current control module and a salinity adjusting module and is used for degrading organic pollutants and disinfecting and sterilizing; the pH adjusting unit is provided with a pH sensor and a pH correction pump and is used for accurately controlling the pH value change in the treatment process; the post-treatment unit comprises an ultrafiltration membrane and activated carbon and is used for removing residual micromolecular organic matters and trace heavy metal ions; the comprehensive monitoring unit integrates a PLC controller, a data acquisition module and a communication interface, and is used for realizing automatic management and remote monitoring of the system.

The invention belongs to the technical field of polymeric membrane materials, and particularly discloses a polycarbonate / cellulose acetate blended ultrafiltration membrane as well as a preparation method and application thereof. The polycarbonate / cellulose acetate blended ultrafiltration membrane is prepared by blending cellulose acetate and polycarbonate, and has the advantages of simple preparation method, low cost, low energy consumption, good stability and the like; meanwhile, the double advantages of polycarbonate and cellulose acetate are combined, remarkable hydrophilic enhancement and efficient permeability are shown, the purpose of separation and purification can be achieved, and the composite material has huge potential application prospects in the fields of seawater desalination, sewage treatment, rainwater collection and treatment and the like.

The embodiment of the invention discloses a method for extracting extracellular vesicles from a traditional Chinese medicine dry product. The method comprises the following steps: taking a dry traditional Chinese medicine product as a raw material, and sequentially performing crushing, soaking, first-order enzymolysis, wall breaking, differential centrifugation, second-order enzymolysis, high-speed centrifugation, ultracentrifugation and ultrafiltration enrichment to obtain the extracellular vesicles. A two-step enzymolysis method is adopted in the enzymolysis process, impurities are removed to the maximum extent in a sequence difference enzymolysis mode, and the structure and function stability of the exosome are protected. According to the invention, the differential centrifugation and the enzymolysis method are alternately used, so that impurities with different sizes and different properties can be removed more thoroughly. According to the method, the cost is strictly controlled, the exosome purification efficiency is relatively high, the concentration of the obtained dry exosome is relatively high, and the operability is extremely high.

The invention provides a low-carbon circulating technological process for treating high-total-nitrogen wastewater. A main treatment unit and a resource recycling and circulating unit are included; the main treatment unit is characterized in that high-total-nitrogen wastewater sequentially passes through a pH regulating tank, a sulfur autotrophic denitrification tank, a biochemical system, a secondary sedimentation tank, a deep treatment line and ultrafiltration reverse osmosis, produced reclaimed water enters produced water for delivery, and a part of produced concentrated water enters a resource recovery and circulation unit; the resource recovery and circulation unit is characterized in that after concentrated water is treated by a vertical electrophoresis device, mixed acid, mixed alkali and low-salt water are separated out, the mixed alkali is sent to a sulfur autotrophic denitrification tank to be used for supplementing alkalinity consumption of the sulfur autotrophic denitrification system, and the mixed acid sequentially passes through an anaerobic regulating tank, an anaerobic reactor, an alkali washing tower, a biological desulfurization reactor and a sedimentation tank; the recovered sulfur can be sold as elemental sulfur or reused in the sulfur autotrophic denitrification tank, and supernate flows back to the alkaline tower; a green, low-carbon and recyclable water treatment process flow is realized.

The invention belongs to the technical field of deep processing of agricultural products, and provides royal jelly protein zymolyte with melanin inhibition activity and preparation and application of the royal jelly protein zymolyte. Performing enzymolysis on the soluble royal jelly protein solution with pepsin to obtain enzymatic hydrolysate; and carrying out ultrafiltration separation on the enzymatic hydrolysate to obtain a polypeptide solution with the molecular weight of less than 3KDa, namely royal jelly protein hydrolysate. The royal jelly is used as a raw material, the royal jelly protein hydrolysate with low molecular weight is prepared by extracting royal jelly protein and utilizing a protease enzymolysis technology and an ultrafiltration separation technology, and the royal jelly protein hydrolysate has good melanogenesis inhibition activity and can reduce generation of mouse melanoma cells and zebra fish melanin. The inhibitor is derived from natural food royal jelly, is green and safe, is controllable in conditions in the preparation process, is convenient to extract, does not need artificial synthesis, and is expected to be applied to food, medicines or cosmetics with a whitening effect.

The utility model discloses a white spirit upgrading ultrafiltration device, and particularly relates to the technical field of white spirit production equipment, the white spirit upgrading ultrafiltration device comprises a filter bin, the middle part of the filter bin extends to the lower end and is symmetrically provided with residue discharge grooves, the output ends of the residue discharge grooves are connected with sealing blocks in a sliding manner, and a motor is fixedly connected below the inner cavity of the filter bin; a transmission structure is fixedly connected to the outer surface of the output end of the motor, a knocking structure is fixedly connected to the right side of the upper portion of the transmission structure, a sweeping structure is fixedly connected to the upper portion of an inner cavity of the filtering bin, and an ultrafiltration membrane is rotationally connected to the middle of the inner cavity of the filtering bin. According to the Baijiu upgrading ultrafiltration device disclosed by the utility model, the ultrafiltration membrane is matched with the sweeping structure and the residue discharge groove, so that impurities and suspended matters filtered by the ultrafiltration membrane can be swept and fed into the residue discharge groove in time, the Baijiu filtering quality is improved, the sweeping structure does not influence the Baijiu filtering in the filtering process, and the filtering speed is also improved; and due to automatic cleaning, the manual labor is reduced.

The invention discloses a method for efficiently separating and purifying plant exosomes and application, and belongs to the technical field of biological nanotechnology. The method comprises the following key steps: (1) performing sterile cleaning on plant raw materials, and then performing peeling or tissue slitting pretreatment; (2) carrying out mechanical crushing treatment by adopting a phosphate buffer solution (PBS), and filtering through a 200-mesh screen to obtain a primary extracting solution; (3) performing gradient centrifugal purification on the extracting solution, collecting supernate, and filtering the supernate through a 0.45 mu m microporous filter membrane; (4) adding 8-12% of polyethylene glycol for low-temperature phase separation and precipitation; (5) purifying by using an electrodialysis technology; and (6) carrying out final concentration by adopting a 100kDa ultrafiltration membrane to obtain the high-purity PELNs preparation. According to the method, the process, equipment and reagents are simple and easy to obtain, the final yield is high, the purity is high, particle size distribution is uniform, and an innovative solution is provided for large-scale industrial production of natural-source nano-drug carriers.

The invention discloses a multi-metal borate nano-particle as well as a preparation method and application thereof. The preparation method comprises the following steps: in the presence of small molecules with alkyl chains, performing high-temperature thermal decomposition on an organic metal compound or a metal salt compound precursor and organic borate in a solvent, and then centrifuging, modifying, performing ultrafiltration, dialyzing and purifying to obtain the multi-metal borate nanoparticles. The preparation method disclosed by the invention has the characteristics of mildness, high efficiency and strong controllability. The multi-metal borate nanoparticles prepared by the preparation method disclosed by the invention have the advantages of monodisperse size, relatively high magnetic property and good biocompatibility. Therefore, the prepared multi-metal borate nanoparticles not only have multi-modal imaging functions such as magnetic resonance imaging, near-infrared two-region imaging, nuclear medicine imaging and magnetic particle imaging, but also can be used for various treatment means such as magnetocaloric therapy and boron neutron capture therapy; potential advantages are realized in biomedical applications such as magnetic targeting tumor treatment and imaging contrast agents, and high practical values are realized.

The invention discloses a system and a method for classified sewage treatment, and belongs to the technical field of environmental engineering and water treatment. The system comprises the following components: an intelligent water quality detection module, which is used for real-time and accurate monitoring of COD, BOD, ammonia nitrogen, total phosphorus, suspended matter concentration and heavy metal content; the sectional bioreactor realizes deep removal of nitrogen and phosphorus and efficient biological treatment by flexibly adjusting reaction conditions of each section; the intelligent flocculation control module is used for automatically and accurately adjusting the adding amount of a flocculating agent, and is combined with integrated operation of efficient inclined tube precipitation and sludge concentration, so that the water quality of discharged water is stable, and the medicament consumption is reduced; the ultrafiltration membrane bioreactor effectively removes residual suspended matters and colloids, and ensures that the effluent stably reaches the standard for a long time through the synergistic effect of catalytic ozonation; and the sludge treatment module is used for realizing collaborative optimization management of sludge reduction, recycling and energy recycling.

The system comprises a raw water tank, a multi-medium filter, a bag filter, a plate heat exchanger, an ultrafiltration device, an ultrafiltration water tank, a primary reverse osmosis device, a secondary reverse osmosis device, a UV (ultraviolet) sterilization device, an EDI (electrodeionization) device, a TOC (total organic carbon) remover, a polishing mixed bed and a terminal filter which are sequentially connected, the RO concentrated water tank is connected with the reverse osmosis concentrated water outlet ends of the primary reverse osmosis device and the secondary reverse osmosis device, the electric driving membrane device is connected with the RO concentrated water tank, and the drainage concentrated water tank is connected with the electric driving membrane device. The reverse osmosis (RO) and electrodeionization (EDI) combined process adopted in the invention comprehensively solves a series of problems of acid and alkali consumption, environmental pollution, poor automation degree, complex system and the like in ultrapure water production. The process equipment disclosed by the invention is relatively high in automation degree, saves the cost required by acid-base regeneration, and does not cause any pollution to the environment.

The invention relates to the field of biological medicine, and provides a preparation method of a fermentation product containing giant salamander peptide, which comprises the steps of stepped enzymolysis pretreatment, staged inoculated fermentation, synergistic enzymolysis and molecular weight grading purification. The method comprises the following steps: firstly, carrying out staged enzymolysis on giant salamander tissues by utilizing pepsin, trypsin and flavourzyme to obtain a primary peptide solution; then, bacillus subtilis, lactobacillus plantarum and bifidobacterium are adopted for directional fermentation, and flora metabolism is optimized through dissolved oxygen control and pH automatic regulation. Then, compound protease is added for secondary enzymolysis, so that the yield of the small molecule peptide is increased. And finally, carrying out ultrafiltration and nanofiltration graded purification, vacuum concentration, freeze drying and gamma-ray sterilization to obtain the micromolecular giant salamander peptide. The molecular weight of the obtained product is mainly distributed within 0.5-5 kDa (lt), and the proportion of 3 kDa is larger than or equal to 80%), the DPPH free radical scavenging rate is larger than or equal to 85%, the ABTS < + > scavenging rate is larger than or equal to 80%, and the obvious anti-oxidation and auxiliary liver protection effects are achieved.

The embodiment of the invention discloses human-derived recombinant III-type collagen as well as a preparation method and application thereof. The amino acid sequence of the human-derived recombinant III-type collagen comprises a basic repetitive unit, and the amino acid sequence of the basic repetitive unit is as shown in SEQ ID NO.4. The amino acid sequence of the basic repetitive unit is as shown in SEQ ID NO.3. The amino acid sequence of the basic repetitive unit is as shown in SEQ ID NO.4. The amino acid sequence of the human recombinant III type collagen is shown as SEQ ID NO.3. The invention also discloses a preparation method of the human recombinant III type collagen. According to the invention, a human recombinant III-type collagen gene with the coding molecular weight of 60kD is designed, an escherichia coli expression strain is constructed and expressed, the yield of the human recombinant III-type collagen is increased through amplification culture on a fermentation tank, and the protein purity is improved by virtue of strategies such as ultrafiltration primary purification and affinity chromatography. The human-derived recombinant III-type collagen prepared by the invention avoids potential hidden dangers such as animal diseases or viruses and immunological rejection caused by a traditional extraction method, has excellent medical performance, can effectively control the production cost and the product quality by virtue of a fermentation preparation process, and is also easy to realize large-scale production.

The invention discloses a preparation method of a high-adsorbability aluminum hydroxide adjuvant for livestock, which comprises the following steps: when an aluminum chloride solution reacts with alkali liquor, generating a colloidal suspension by combining pH two-step adjustment with dispersant addition; and after instant high-speed shearing and room-temperature aging, performing ultrafiltration purification to remove salts, and finally performing moist heat sterilization to obtain the suspension morphological adjuvant. The adjuvant is high in antigen adsorption rate, low in 72-hour desorption rate, large in specific surface area, uniform in particle and suitable for vaccines of pigs, cattle and poultry, and the problems that a traditional adjuvant is low in adsorption rate and poor in stability are solved.

The invention relates to the technical field of wastewater treatment, and discloses a double-membrane reclaimed water recycling device and a recycling method.The double-membrane reclaimed water recycling device comprises a support and an ultrafiltration membrane tank arranged in the support, a reverse osmosis membrane tank is fixed in the support, a settling tank is fixed in the support, a water storage tank is fixed in the support, and the double-membrane reclaimed water recycling device further comprises a tubular ultrafiltration membrane, a water storage tank and a water storage tank, the ultrafiltration membrane tank is fixed in the ultrafiltration membrane tank; the tubular reverse osmosis membrane is fixed in the reverse osmosis membrane tank; the wastewater is efficiently treated; when to-be-treated water is in a normal working state, the cleaning float bowl is driven by water pressure to move up and down in the tubular ultrafiltration membrane and the tubular reverse osmosis membrane: on one hand, intercepted substances attached to the wall surfaces of internal channels of the tubular ultrafiltration membrane and the tubular reverse osmosis membrane are scraped by a first cleaning scraping ring, a second cleaning scraping ring and a spiral scraping ring; on the other hand, intercepted objects attached to the scraping rings are washed and cleaned by means of water flow pressure, the intercepted objects are discharged through the spiral drainage channel, and therefore self-cleaning of the cleaning buoy is achieved.

The invention provides a circulating blow-down water treatment device and process based on a crystallization and granulation fluidized bed coal-fired power plant. The device comprises a cooling tower pool, a multi-medium filter, a crystallization and granulation fluidized bed, a circulating blow-down water buffer pool, a high-density clarification pool, a plug flow channel, a variable-porosity filter pool, a clarification water pool, a self-cleaning filter, an ultrafiltration device, an ultrafiltration water tank, an ultraviolet sterilizer, a security filter and a reverse osmosis device which are connected in sequence. According to the scheme, by introducing induced crystallization for hardness removal and synergistic silicon removal, deep precision treatment can be performed on the circulating sewage, quality-divided recycling is realized, and gradient utilization of water resources is realized; in addition, in the treatment process, the use of chemicals polluting the environment is reduced, the entry of chlorine radicals is avoided, and the great increase of the amount of the recycled desulfurization wastewater is effectively reduced.

The invention relates to the technical field of biological medicine, in particular to a hepatitis A inactivated vaccine and a preparation method thereof. Comprising the following steps: cell amplification, virus culture, virus harvesting, cell disruption, ultrafiltration concentration, inactivation, purification and finished product obtaining. The virus culture comprises the following steps: separating from excrement of a hepatitis A patient and carrying out adaptive passage to obtain a virus strain; adding a carrier into a bioreactor, sterilizing for later use, inoculating a virus strain into a collected cell suspension, and transferring into the bioreactor for culturing; the cell disruption step comprises the following steps: carrying out ultrasonic oscillation on a collected virus harvesting liquid to obtain a cell disruption liquid; trichloromethane is added for extraction and centrifugation, and supernatant virus liquid is collected; the invention provides a preparation method of a hepatitis A inactivated vaccine, which is used for preparing the efficient, safe and stable hepatitis A inactivated vaccine by optimizing virus culture and inactivation processes. The method has the advantages of high virus yield and low production cost, and is suitable for large-scale production and application.

The invention relates to the technical field of elastin peptides, in particular to a method for extracting elastin peptides from animal cartilage, which comprises the following specific steps: removing surface connective tissues and fat from animal cartilage, cleaning with normal saline, grinding and degreasing to obtain pretreated cartilage particles; putting the pretreated cartilage particles into a container, adding ionic liquid and stirring; after stirring is completed, centrifugally collecting precipitates; adding the precipitate into a phosphate buffer solution to form a suspension; adding an immobilized compound enzyme, and carrying out an enzymolysis reaction; after the enzymolysis is completed, raising the temperature for inactivation; filtering to obtain enzymatic hydrolysate; adding macroporous resin into the enzymatic hydrolysate, and filtering to obtain clear liquid; and carrying out ultrafiltration on the clear liquid to obtain the elastin peptide. The ionic liquid interacts with impurities in the animal cartilage, so that the impurities are easier to remove, a purer raw material environment is created for subsequent elastin peptide extraction, and the extraction efficiency is improved.

The invention discloses a double-layer aeration system for preventing wire breakage and sludge deposition of an MBR double-layer component membrane pool, which comprises a raw water pool, a raw water inlet peristaltic pump, an MBR double-layer component membrane pool, a perforated aeration pipe, a pulse aeration box, an aeration pump, a gas meter, a water outlet gear pump, an ultrafiltration membrane component, a pressure sensor, a transmembrane pressure difference display, a sludge discharge peristaltic pump and a water outlet pool, the MBR double-layer assembly membrane pool comprises a first MBR membrane assembly and a second MBR membrane assembly, the first MBR membrane assembly and the second MBR membrane assembly are arranged in parallel, and the perforated aeration pipe and the pulse aeration box are configured to be used as aeration assemblies of the first MBR membrane assembly and the second MBR membrane assembly. According to the invention, the membrane is physically scrubbed by utilizing different aeration modes and a double-layer aeration mode, so that the phenomena of membrane pollution, sludge accumulation and wire breakage are effectively relieved, a reliable theoretical basis is provided for transforming an MBR membrane tank into a double-layer aeration mode in a water purification plant using the MBR hollow fiber membrane, and meanwhile, the method has important significance on reducing pollution and carbon.

The invention relates to the technical field of water treatment equipment, in particular to a coaxial nested ultrafiltration and nanofiltration integrated water purification device and system.The coaxial nested ultrafiltration and nanofiltration integrated water purification device comprises a main shell, and an annular ultrafiltration treatment area and an inner nanofiltration treatment area are coaxially arranged in the main shell. An energy storage adjusting assembly is arranged in the nanofiltration treatment area and comprises an elastic breathing sleeve coaxially arranged outside the nanofiltration membrane assembly in a sleeving mode. The sleeve elastically expands during filtering, so that the effects of buffering pressure and storing energy are achieved; and turbulent flow convex ribs can be arranged on the inner wall of the sleeve, so that the nanofiltration membrane is physically cleaned when the sleeve retracts. Besides, a backwashing pipeline and a valve are arranged, linkage control is carried out when the control unit detects that expansion of the sleeve exceeds the limit, and ultrafiltration produced water stored on the nanofiltration side is reversely pushed by utilizing pressure energy released by retraction of the sleeve so as to backwash an ultrafiltration membrane. According to the invention, the cooperation of pressure buffering, online cleaning of the nanofiltration membrane and energy storage backwashing of the ultrafiltration membrane is realized, the operation is stable, the efficiency is high, and the energy is saved.

The invention discloses a boron manganese tannate nanoparticle as well as a synthesis method and application thereof. The synthesis method of the tannic acid boron manganese nanoparticles comprises the following steps: sequentially dropwise adding a bivalent manganese salt solution, a boric acid solution, a polyethylene glycol solution and a bovine serum albumin solution into pure water under water bath ultrasonic or magnetic stirring to obtain an assembly stock solution, and adding a tannic acid solution into the assembly stock solution to initiate assembly; and continuously carrying out water-bath ultrasonic treatment or magnetic stirring for a period of time, and then carrying out ultrafiltration to remove free drug molecules, so as to obtain the boron manganese tannate nanoparticles capable of mediating boron neutron capture therapy and magnetic resonance imaging. The boron manganese tannate nanoparticles can improve the boron intake in tumors and prolong the retention time of boron atoms in the tumors in boron neutron capture therapy, drug distribution is monitored through the nuclear magnetic resonance imaging technology, then the treatment effect of the boron neutron capture therapy is improved, the preparation method is simple, the stability is good, the size is uniform, the boron loading amount is high, and the application prospect is wide. The biological safety is good, and the repeatability is high.

The utility model discloses a puncture trocar fixing device for ascites ultrafiltration concentration reinfusion. The puncture trocar fixing device comprises a reinfusion system, a catheter, a puncture needle, a fixing mechanism and an application. The plaster is characterized in that the plaster body is pasted on the skin, a clamping groove is formed in the upper portion of the plaster body, and a fixing mechanism is detachably installed on the clamping groove; the fixing mechanism comprises an arch frame detachably connected with the clamping groove, limiting grooves formed in the arch frame at the interval of 1 cm, sliding grooves formed in the middles of the inner sides of the limiting grooves, and limiting cylinders installed in the sliding grooves in a sliding mode. The puncture needle is detachably installed in the limiting cylinder, one end of the puncture needle is connected with the catheter, and the other end of the catheter is connected with the feedback system. The puncture needle can be fixed in the long-time treatment process, the puncture needle is prevented from being disengaged, swung and broken, and medical staff can be assisted in puncturing.