479 results about "Protein composition" patented technology

The invention belongs to the technical field of biology, and particularly relates to a sweet protein composition as well as a preparation method and application thereof. The sweet protein composition comprises the following sweet proteins: at least one of Brazilian sweet protein, kiwi sweet protein, omethoate sweet protein, rhizoma curculiginis sweet protein, capparis masaikai sweet protein, miracle fruit element, petatin, thaumatin and agrocybe cylindracea sweet protein. The invention also provides a preparation method of the sweet protein composition, and the preparation method simplifies the purification process and significantly improves the purity and yield of the sweet protein. The sweet protein composition disclosed by the invention is suitable for various foods, beverages, medicines and health-care products, so that the taste of the medicines is improved, and the compliance of patients is improved. In addition, the sweet protein composition can also be used in weight-losing products, antioxidant supplements and health-care products for enhancing immunity, and oral care products such as toothpaste and mouth wash, and can provide pleasant sweetness and improve mouth feel.

The present invention relates to a whey protein product and a preparation method therefor. The product is derived from a whey protein-based protein composition, and the protein composition comprises at least a portion of whey protein degradation components, wherein protein components in the protein composition have a molecular weight distribution of: (i) the content of the protein component having a molecular weight of less than 5000 Da is 80-96% by mass; (ii) the content of the protein component having a molecular weight of 5000 Da to 10,000 Da is 0.5-10% by mass; and (iii) the content of protein component having a molecular weight of greater than 10,000 Da is 0-10% by mass, the content being the content of each of the three protein components in the total protein components based on dry weight.

Disclosed are methods of treating radiation-induced skin damage comprising administering extracellular vesicle and protein compositions.

The invention discloses an application of MAPK-related protein for regulating plant type and growth and development of plants. The invention belongs to the field of botany, and particularly relates to application of MAPK related protein for regulating plant type, growth and development. The invention provides a method for regulating and controlling plant type and growth development, which comprises regulating and controlling the activity and / or content of protein in a target plant, or / and regulating and controlling the expression quantity of a coding gene of the protein so as to regulate and control the plant type and growth development of the plant. The protein is the following protein: a composition consisting of a protein FvMAPK3 of which the amino acid sequence is SEQ ID No. 3 and a protein FvMAPK6 of which the amino acid sequence is SEQ ID No. 6. Experiments prove that the expression of the two proteins FvMAPK3 and FvMAPK6 is reduced, so that the plant type and growth and development of strawberries can be regulated and controlled, and important theoretical significance is achieved for strawberry breeding.

Methods of treating lumbar facet joint syndrome by administering extracellular vesicle and protein compositions.

The invention relates to a molecular model for auxiliary diagnosis of diabetic nephropathy based on proteomics detection of serum specimens of patients with diabetic nephropathy and non-diabetic nephropathy as well as a construction method and application of the molecular model, which can effectively screen out biomarkers for auxiliary diagnosis model construction and combine with important clinical variables to construct a clinical auxiliary diagnosis model. According to the technical scheme, the molecular model is formed by combining proteins MTTP, TNNI1 and ANGPTL8, the MTTP ratio of diabetic nephropathy patients to non-diabetic kidney disease patients is 8-12.5, the TNNI1 ratio is 7-15, and the ANGPTL8 ratio is 8-14, the protein composition in a sample is detected through a high-throughput mass spectrum means, and the molecular model has the advantages that the molecular model is simple in structure, convenient to operate and high in sensitivity, and the detection accuracy is high. The difference of a diabetic nephropathy patient group and a non-diabetic nephropathy group in the proteomics level is compared, the biomarker for auxiliary diagnosis model construction is screened out, and a new scheme is provided for auxiliary diagnosis of diabetic nephropathy.

A first brine free of salt and phosphate for treating a food product by injection of the brine into the food product. The brine is formed from an emulsion consisting of water, saltless flavoring and protein. The protein is from the same type of food product as the food product being injected with the brine. A second brine especially for ham with the bine being similar to the first brine, but with a low sodium content of a maximum of 0.5% to 1.0% of the weight of the food product. A third brine for pork bellies without phosphate.

The invention belongs to the technical field of food, and particularly relates to a high-satiety liquid protein composition as well as a preparation method and application thereof. The high-satiety liquid protein composition is characterized by being prepared from the following raw materials in parts by weight: 800 to 1000 parts of protein, 110 to 160 parts of vegetable oil, 700 to 800 parts of carbohydrate, 120 to 150 parts of dietary fiber, 5 to 15 parts of vitamin, 1 to 8 parts of mineral substance, 35 to 40 parts of emulsifier, 12 to 15 parts of stabilizer, 17 to 20 parts of pH regulator and 5 to 10 parts of essence. Under the comprehensive action of all the components, the liquid protein composition can keep the milk state stable, fat components are not subjected to lactation separation, protein components are not subjected to sedimentation and layering, the macroscopic state is stable, and nutrients in the product are uniformly distributed.

The present disclosure provides a method of preparing a lyophilized bispecific molecule composition comprising (a) inducing ice nucleation in a liquid protein composition having a bispecific molecule concentration of at least about 10 mg / ml in a vial exposed to a first temperature of about-18 DEG C to about-10 DEG C for about 60 minutes to about 270 minutes; (b) exposing the vial of (a) to a second temperature of about-25 DEG C to-50 DEG C for about 1 hour to about 5 hours; and (c) drying the composition of (b) at a third temperature of about-5 DEG C to about-25 DEG C for about 25 hours to about 70 hours, and (d) further drying the composition of (c) at a fourth temperature of about 25 DEG C to about 50 DEG C for about 4 hours to about 12 hours to obtain a vial comprising a lyophilized bispecific molecular composition, the composition has a percentage content of high molecular weight material (HMWS) of less than or equal to about 1.5% (mA / ). The disclosure further provides lyophilized bispecific molecule compositions prepared via the methods described herein.

Soybean plants producing seeds and soybean seeds comprising increased protein content are provided. Also provided are soybean plants producing seeds and soybean seeds comprising increased amounts of essential amino acids such as methionine, tryptophan or lysine. Protein compositions having increased essential amino acids can be made from the soybean seeds. Additionally, methods for generating and using plants, seeds and protein compositions having increased protein content or increased amounts of essential amino acids are disclosed.

The present invention provides an infant formula milk powder and a preparation method thereof. The infant formula milk powder contains a protein composition capable of improving the digestibility of protein in the infant formula milk powder; wherein, based on the total protein content of the infant formula milk powder as 100%, the protein composition contains 13.0%-50.5% of α-lactalbumin and 15.0%-35.0% of β-casein. The technical solution of the present invention can significantly improve the digestibility of whey protein in infant formula milk powder.

Disclosed herein are transformed plants, plant tissues, plant parts, plant cells, and plant seeds comprising a recombinant nucleic acid molecule encoding a polypeptide having pesticidal activity. Also disclosed herein are methods of protecting or treating a plant from infection by a plant pathogen or pest by transforming plants, plant tissues, plant parts, plant cells, and plant seeds with a recombinant nucleic acid molecule encoding a polypeptide having pesticidal activity.

The present invention induces differentiation of mesenchymal stem cells and osteoblast precursor cells into osteoblasts. Provided is a medium for culturing stem cells, the medium including 60-90 vol% basal medium and 10-40 vol% physiological saline, to which 1-100 ng / mL of EGF, 0.2-20.0 ng / mL of FGF-2, 0.2-20.0 ng / mL of PDGF, and 0.5-8.0 mM of magnesium ascorbyl phosphate are further added.

The present invention discloses a method for producing protein HFBI. The method comprises the following steps: infecting insect cells with a recombinant baculovirus containing an insect cell expression vector expressing a fusion protein, and collecting the supernatant; the fusion protein is composed of a GP64 signal peptide and a protein HFBI; the amino acid sequence of the GP64 signal peptide is shown in SEQ ID NO:2 from the 1st to the 20th position from the N-terminus; then the supernatant is precipitated with ammonium sulfate to obtain a large amount of protein HFBI, and finally the protein is further purified by heating using the thermal stability. The purity of the protein HFBI obtained by the method provided by the present invention is more than 95%, the concentration is 6 mg / ml, and it has biological activity. It can be seen that the present invention can significantly increase the yield of protein HFBI, and the production process is simple, which can be fully applied to actual production. The present invention has important application value.

The invention discloses a bionic fetal fat skin care composition for children as well as a preparation method and application thereof, and belongs to the technical field of skin care products. The bionic fetal fat skin care composition comprises a plant extract, a bionic fetal fat composition, a protein mixture, a regulating agent and bionic liquid. The plant extract and the bionic body fat composition are used for simulating lipid composition of body fat, the formed skin care composition has the effects of resisting oxidation, moistening and preserving moisture, promoting cell renewal and the like, and a protective layer can be formed on the surface of skin, so that the defense capacity of the skin is improved. The protein composition is added into the bionic fetal fat skin care composition, so that the skin state can be improved, the absorption of other components in the skin composition can be promoted, and the overall effect of the skin care composition is improved. The skin care composition disclosed by the invention does not contain irritating components, does not cause irritation and burden to the skin, and can be used for preparing skin care products for children.

This invention relates to CTLA-4 protein compositions and their use in the mitigation of autoimmune adverse events associated with cancer immunotherapy.

The present invention relates to the pharmaceutical compositions of lectin proteins and its use for the prevention, treatment and cure of inflammation, including inflammatory disease. The invention specifically relates to the pharmaceutical compositions for topical application comprising lectin proteins and its use for prevention, treatment and cure of inflammation due to chemotherapy and / or radiotherapy. The lectin may comprise an amino acid sequence having sequence of SEQ ID NO: 1 or at least 70% homology to SEQ ID NO: 1.

The invention relates to a molecular model established based on proteomics detection serum specimens and used for assisting in evaluating the renal injury progress of diabetic nephropathy as well as a construction method and application of the molecular model, new disease diagnosis markers can be found, and an existing disease diagnosis system can be optimized; according to the technical scheme, a proteomics technology is combined with various medical diagnosis technologies such as experiments and images through research thinking logic of evidence-based medicine and clinical epidemiology so as to diagnose whether a patient suffers from diseases or not and identify different diseases, and the molecular model is formed by combining proteins P23396 + P0CG47 + Q9NYQ8 + P63241, according to the present invention, the protein composition in the sample is detected by using the high-throughput mass spectrometry means, the difference of the diabetic nephropathy disease group and the non-disease group on the proteomics level is compared, the biomarker for the disease progress auxiliary evaluation model construction is screened, and the new scheme is provided for the disease progress auxiliary evaluation of the diabetic nephropathy.

Compositions of bacterial tyrosyl-tRNA synthetase mutants that enable site-specific incorporation of numerous unnatural amino acids into proteins expressed in eukaryotic cells or in engineered ATM E. coli and methods of use are described. Compositions of novel unnatural amino acids that can be incorporated using these mutant bacterial tyrosyl-tRNA synthetase are also described.

The invention belongs to the technical field of biology, and particularly relates to a differential characteristic polypeptide library for identifying different medicinal parts of bufo bufo gargarizans and application of the differential characteristic polypeptide library. In the prior art, toad venom is different from toad skin, toad meat and toad bone in protein components, but detection of protein macromolecules is tedious, and conversion from a method to a standard is not facilitated. The polypeptide is used as an index component to identify and analyze the venenum bufonis and dried toad medicinal materials, the specificity is high, the stability is good, the interference of the processing process is avoided, multiple medicinal materials can be identified at the same time, and the advantages are obvious.

The invention relates to the technical field of microbial fermentation, in particular to a fermented fish protein composition and a preparation process thereof. The preparation process of the fermented fish protein composition comprises the following steps: adding a substrate, compound zymophyte and the like into a fermentation container for fermentation; taking part of the fermentation liquor, heating for denaturation and low-temperature renaturation, adding the mesoporous silica carrier, and introducing into the fermentation container again; and continuously monitoring, and after fermentation is completed, carrying out solid-liquid separation and subsequent treatment on the fermentation liquid to obtain the fermented fish protein composition. The enzyme is immobilized through combination of heating denaturation and low-temperature renaturation, so that certain inhibitory structures in enzyme molecules can be broken, the enzyme is easier to interact with other molecules, the activity of the enzyme molecules is recovered, specific binding between the enzyme and the mesoporous silica carrier is promoted, and the immobilization efficiency is improved; the immobilized enzyme shows higher stability and activity, the service life is prolonged, and the loss of the enzyme is reduced, so that the fermentation efficiency is improved.

Compositions and methods for controlling insect pests are disclosed. In particular, novel insecticidal proteins having toxicity to at least coleopteran insect pests are provided. Nucleic acid molecules encoding the novel insecticidal proteins are also provided. Methods of making the insecticidal proteins and methods of using the insecticidal proteins and nucleic acids encoding the insecticidal proteins of the invention, for example in transgenic plants to confer protection from insect damage, are also disclosed.

The present invention provides a botulinum toxin protein composition, mainly comprising botulinum toxin protein, a saccharide, a salt, and human serum albumin. The botulinum toxin protein composition of the present invention features good activity and stable properties, and can maintain the activity of the botulinum toxin protein at a high level after long-term storage.

The present invention discloses a novel protein composition comprising a first protein or polypeptide selected from a specific group. The protein composition has a broad-spectrum and efficient treatment effect on inflammatory diseases. The invention also discloses a preparation method of the protein composition and application of the protein composition in preparation of medical implants, medical devices or drugs.

The invention relates to the technical field of cosmetics, in particular to the field of IPCA61K8, and more particularly relates to an ECM protein composition with anti-wrinkle, firming, repairing and moisturizing effects and application thereof. The composition is prepared from collagen, second protein and sodium coralate. The weight ratio of the collagen to the second protein to the sodium currate is (1-5): (10-25): (1-5), and the anti-wrinkle, firming, repairing, soothing and moisturizing mask has good permeability and has excellent anti-wrinkle, firming, repairing, soothing and moisturizing effects.

A scaffold comprising electrospun decellularized ECM of an organ, wherein the decellularized ECM has a similar protein composition to native ECM of the organ. Methods of generating same are also disclosed as well as uses of same.

Methods are disclosed for making a high protein, pliable food composition that remains pliable over a shelf life of at least 6 months, and food compositions made by disclosed methods. Food products containing disclosed food compositions are also disclosed.

The invention discloses an application of an MAPK related protein for regulating and controlling the flowering phase and fertility of plants. The invention belongs to the field of botany, and particularly relates to application of MAPK related protein for regulating and controlling the flowering phase and fertility of plants. The invention provides a method for regulating and controlling the flowering phase and fertility of a plant, which comprises the step of regulating and controlling the activity and / or content of protein in a target plant, or / and regulating and controlling the expression quantity of a coding gene of the protein, so as to regulate and control the flowering phase and fertility of the plant. The protein is the following protein: a composition consisting of a protein FvMAPK3 of which the amino acid sequence is SEQ ID No. 3 and a protein FvMAPK6 of which the amino acid sequence is SEQ ID No. 6. Experiments prove that the flowering phase and fertility of the strawberries can be regulated and controlled by reducing the expression of the two proteins FvMAPK3 and FvMAPK6, and important theoretical significance is achieved for strawberry breeding.

The present invention relates to a method to increase the physical stability of a β-lactoglobulin and to a β-lactoglobulin with increased physical stability. The present invention further relates to the use of an extraneous β-lactoglobulin to enhance the physical stability of a composition comprising a protein and the extraneous β-lactoglobulin.

To provide a heating cooker and a heating cook system which improve taste of artificial rice containing protein as a main component, eaten by a user.SOLUTION: A heating cooker includes: a container housing a heated product; a heating part heating the container; and a control device controlling the heating part to heat the container to a target temperature. The control device executes a normal mode executed when the heated product is rice and an artificial rice mode executed when the heated product is artificial rice constituted by protein as a main component. In the normal mode and the artificial rice mode, a heating process of heating the container and pregelatinizing starch contained in the heated product is performed. The target temperature in the heating process of the artificial rice mode is lower than the target temperature in the heating process of the normal mode.SELECTED DRAWING: Figure 4