74 results about "Disease progress" patented technology

This invention is directed to offer a customizable, cost effective, and comfortable soft gripping solution for patients with chronic disabilities, such as diabetic neuropathy, allowing the patients to function independently and perform routine daily tasks. A soft robotic gripper has been developed with one or more inflatable systems actuated by aft to assist a user to grip an object. The main body of the gripper bends with air actuation while the fingertip actuation helps functionality in the extremities. The gripper is further enhanced by adding sensors that integrate feedback for sensitivity to touch, conformability, and grip ability. The modular design modifications allow for gripper adjustments as the disease progresses or rescinds. The gripper also works as a training aid for routine physical therapy exercises. Data collected by a microprocessor can also help learn more about these chronic diseases and use artificial intelligence to customize treatment regimens for individual patients.

The invention belongs to the field of medicine, and particularly relates to a new application of human urine kininogenase and a medicine composition comprising the human urine kininogenase. The human urine kininogenase is applied to prepare medicine for treating the Alzheimer's disease. The invention further provides the medicine composition for treating the Alzheimer's disease. The medicine composition comprises the human urine kininogenase and bilobalide, and further comprises pentoxifyline. The medicine composition can remarkably recover the memory capacity of a patient suffering with the Alzheimer's disease, improve the cognition capacity of the patient suffering with the Alzheimer's disease, delay the disease progress of the Alzheimer's disease, greatly improve the life quality of the patient suffering with the Alzheimer's disease, improve the treatment compliance of the Alzheimer's disease, improve the treatment effect, provide the effective treatment medicine for the patient suffering with the Alzheimer's disease, and greatly relieve pain of the patient of the Alzheimer's disease.

The invention relates to a Chinese herbal preparation for treating ankylosing spondylitis, which comprises the following Chinese medicinal herbs by weight: 10g of rhizoma cibotii, 15g of pilose antler, 10g of himalayan teasel root, 5g of scorpio, 15g of kudzu vine root, 12g of chuanxiong rhizome, 5g of caulis spatholobi, 15g of white paeony root, 15g of common peony root, 10g of safflower carthamus, 15g of medicinal cyathula root and 10g of white mustard seed. The Chinese herbal preparation is prepared by using the steps of: weighing the Chinese medicinal herbs in the formula, adding 1500ml of water, decocting with slow fire to ensure that medicine liquid is concentrated to 250ml, filtering dregs of a decoction and preparing a decoction. During the treatment, the decoction is taken orally, each dosage is taken every day, and one treatment course includes 90 days. The Chinese herbal preparation is used for treating the ankylosing spondylitis through improving immunity and micro circulation and eliminating blood micro coagulation. The Chinese herbal preparation has the functions of inhabiting fibrosis and ossification, inhibiting or repairing bone destruction and the like, and achieves the purposes of releasing symptoms and inhibiting the disease progressing from multiple aspects and multiple links. The Chinese herbal preparation has the advantages of low cost and no toxic and side effects.

The invention relates to a traditional Chinese medicinal composition for brightening and spot-removing and a preparation method of the preparation. Raw components of the traditional Chinese medicinal composition comprise: by weight, 25-35 parts of pseudostellaria root, 10-20 parts of Cyperus Rotundus L, 6-10 parts of scorpion, 8-12 parts of muscardine silkworm, 15-25 parts of Poria cocos, 15-25 parts of dahurian angelica root, 25-35 parts of radix paeoniae rubrathe, 15-25 parts of Chinese angelica, 15-25 parts of cynanchi root, 8-12 parts of folium callicarpae pedunculalae, 25-35 parts of Ligusticum wallichii, 25-35 parts of motherwort, 10-20 parts of szechwan Chinaberry fruit, 20-30 parts of Artemisia anomala and 20-30 parts of ginger juice. The preparation method comprises the following steps: mixing, crushing, adding 75% ethanol and carrying out reflux extraction for 2-3 times, merging filtrates, concentrating to obtain a thick extract, and drying to obtain pulvis. The traditional Chinese medicinal composition has advantages of comprehensive conditioning specific to cause of disease, fast pharmaceutical effectiveness and little side effect, can be used to achieve the purpose of internal and external treatment combination and simultaneous treatment of principal and subordinate symptoms, inhibit disease progresses, make skin to be recovered to former levels and obviously shorten course of disease, has obvious treatment effects, and is worth popularizing and applying.

The invention discloses a heptapeptide with a function of resisting Abeta42 protein aggregation and application of the heptapeptide as well as a gene for encoding the polypeptide. The synthetic peptide has the efficacy of obviously resisting the Abeta42 protein aggregation, and further has the effects of improving memory and delaying disease progress of Alzheimer's disease; the synthetic peptide can be widely applied to preparation of a medicine or food for resisting the Abeta42 protein aggregation, or is applied to preparation of a medicine or food for preventing or treating the Alzheimer's disease, and can further effectively prevent and treat neurodegenerative diseases including AD disease so as to improve medical conditions of the neurodegenerative diseases; the heptapeptide has greatsocial and economic benefits.

The invention discloses an Alzheimer's disease progress prediction method, a patient is measured in a fixed time interval to obtain multi-view data, and the Alzheimer's disease progress prediction method comprises the following steps: preprocessing the multi-view data; processing the multi-view data by using a multi-view fusion neural network to obtain a hidden representation matrix shared by each view; introducing a minimum gating unit into the implicit representation matrix so as to fill missing multi-view data and predict score data of a future time point; and carrying out cooperative training on the multi-view fusion neural network and the minimum gating unit by using the multi-view data so as to predict the disease development process. According to the method, the hidden representation matrix shared among the views is obtained for the multi-view data of each time point through the multi-view fusion neural network, meanwhile, the data, obtained through prediction of the minimum gating unit, of the next time point is used for filling missing data, and score data prediction of any time point in the future is conducted through the minimum gating unit.

The invention constructs Klebsiella oxytoca containing luciferase gene cluster (luciferase gene cassette, lux) by utilizing plasmid construction and an electric transformation technology. Through autofluorescence identification, a subculture stability test of strains and observation of culture characteristics, the Klebsiella oxytoca (KOX-LUX) capable of stably expressing luciferase is finally obtained. An important visual research tool is provided for researching the progress of Klebsiella oxytoca related diseases and screening proper sterilization methods, antibiotics and the like.

This invention is directed to appropriately searching for case data similar in the process of a disease. A similar case search apparatus (100) according to this invention includes a disease progress model building function of building a disease progress model by extracting feature amounts from a plurality of medical images obtained by imaging the same object in different periods, a unit configured to read out case data, a unit configured to acquire inspection data, a similar case search function of interpolating, by using the model, feature amounts extracted from the plurality of medical images contained in the inspection data, and calculate a similarity between the inspection data and the case data by using the interpolated feature amounts, and a monitor (111) which displays case data selected based on the calculated similarity.

An agent for the prevention, treatment and / or inhibition of progression of an ophthalmic disease and an agent for the protection of an optic nerve, each of which comprises (2R)-2-propyloctanoic acid or a salt or prodrug thereof in which an amount per dose is from 0.3 ng to 5000 mg. The agents are useful for an ophthalmic disease, such as glaucoma, cataract, retinal detachment, muscae volitantes, age-related macular degeneration, diabetic retinopathy, macular edema, myopia, asthenopia, dry eye, amaurosis fugax, choked disc, papillitis optica, retrobulbar neuritis, toxic amblyopia, optic atrophy, higher visual pathway lesion, internuclear opthalmoplegia, gaze palsy and ischemic optic neuropathy.

The invention discloses liver-protecting traditional Chinese medicine health food. The liver-protecting traditional Chinese medicine health food is prepared from components in parts by weight as follows: 50-300 parts of herb of Penthorum chinense Pursh, 1-10 parts of folium ginkgo, 3-20 parts of radix paeoniae alba, 5-20 parts of tea polyphenol, 5-30 parts of radix astragali, 1-10 parts of radix glycyrrhizae, 1-10 parts of taurine and 1-15 parts of broccoli. The invention further discloses a preparation method of the liver-protecting traditional Chinese medicine health food. The liver-protecting traditional Chinese medicine health food and the preparation method have the following advantages: (1) traditional Chinese medicine theories are used as guidance and combined with modern pharmacological research results, physiological properties of the liver and characteristics of progress of liver diseases are considered fully, the treatment guidelines of removing dampness, descending turbid,nourishing the liver and the kidney, reinforcing qi, nourishing blood, activating blood and regulating qi are embodied, and the treatment and health care effects are quite good; (2) selected raw materials of the health food are food or articles which can be applied to the health food, the processing technology is reasonable, safety and effectiveness of the product are guaranteed, and the health food can be applied to liver protection and disease progress treatment of patients suffering from the liver diseases and can also be applied to prevention for people with liver injury trend.

The present invention provides pharmaceutical compositions useful as agents for the inhibition of progression of diseases associated with abnormal accumulation of liver lipids. In particular, the pharmaceutical compositions of the present invention which comprise as an active ingredient a sodium / glucose co-transporter 2 inhibitor are highly suitable as an agent for the inhibition of progression of not only common fatty liver but also non-alcoholic fatty liver disease (NAFL), non-alcoholic steatohepatitis (NASH), hypernutritive fatty liver, diabetic fatty liver, alcoholic fatty liver disease toxic fatty liver or the like.