1229 results about "Molecular level" patented technology

A method to be implemented on or in a computer is disclosed, where the method includes data collection, calibration, candidate selection, and analysis of data streams associated with each candidate to classify single molecule fluorescence resonance energy transfer events. Once classified, the classification can be related to the nature of the events, such as the identification of dNTP incorporation during primer extension to obtain a base read out of an unknown template.

Stand-alone microsystems adapted for performing combinatorial detection of bioagents at single molecule level wherein the microsystems are featured with three-dimensional microarray and multi-layer microfluidics to thereby provide high throughput screening and high content screening sufficient to allow for substantially real-time performance of the microsystem. Methods for detection of bioagents at a single molecule level or single organism level include providing a reconfigurable microsystem adapted for performing combinatorial detection of bioagents at a single molecule level and reconfiguring the reconfigurable microsystem for various environments.

A bio-implantable electrochemical cell system for active implantable medical devices. In one embodiment, the fuel cell includes an electrode structure consisting of immobilized anode and cathode enzymes deposited on nanostructured high-surface-area metal nanowires or carbon nanotube electrodes. The anode enzyme comprises immobilized glucose oxidase and the cathode enzyme comprises immobilized laccase. Glucose is oxidized at the surface of the anode and oxygen is reduced at the surface of the cathode. The coupled glucose oxidation-oxygen reduction reactions provide a self-generating current source. In another embodiment, the nanowires or carbon nanotubes, along with the adjacent surface anode and cathode electrodes, are coated with immobilized glucose oxidase and immobilized laccase containing biocolloidal substrates, respectively. This results in the precise construction of an enzyme architecture with control at the molecular level, while increasing the reactive surface area and corresponding output power by at least two orders of magnitude.

The invention discloses a recombinant humanized collagen. Its amino acid sequence is as shown in SEQNO.3 and has 599 amino acids. The molecular weight is 55.0kDa. A preparation method of the recombinant humanized collagen comprises the following steps of: constructing a gene engineering strain for the expression of the recombinant humanized collagen to obtain a Pichia pastoris engineering strain; carrying out fermentation culture on the engineering strain, and realizing inducible expression of the recombinant humanized collagen to obtain a recombinant humanized collagen fermentation broth; and purifying the fermentation broth to obtain the recombinant humanized collagen. The humanized collagen gene Ge1 designed in the invention is a brand-new sequence which is greatly shorter than a natural humanized collagen gene (Kbp) in length. By the preparation method, operation simplification at the molecular level is realized, and the gene engineering strain fermentation production of the collagen is more easily realized. The humanized collagen gene Ge1 contains characteristics of a natural humanized collagen gene. And simultaneously, its expressed protein has excellent characteristics of a natural humanized collagen.

To gain a better understanding of brain tumor angiogenesis, new techniques for isolating brain endothelial cells (ECs) and evaluating gene expression patterns were developed. When transcripts from brain ECs derived from normal and malignant colorectal tissues were compared with transcripts from non-endothelial cells, genes predominantly expressed in the endothelium were identified. Comparison between normal- and tumor-derived endothelium revealed genes that were specifically elevated in tumor-associated brain endothelium. These results confirm that neoplastic and normal endothelium in human brains are distinct at the molecular level, and have significant implications for the development of anti-angiogenic therapies in the future.

The application of a gas analyzer for gas mud logging is presented to measure gases in the return mud flow used in drilling processes. A supported membrane extraction probe from the analyzer is inserted into the mud flow. The probe extracts target gases from the mud through the membrane. Extracted gases are transported by an internal pump to an internal gas sensor unit. The infrared sensor unit is utilized to subject the gases to infrared emitted energy to excite the gasses at a molecular level for sensing and detection. The sensor then transfers sensed values electronically to a digital conditioning board. As the data is digitized in the conditioning board it is encoded with information to enable a means of correlating the derived sensor data. The data is then sent to a digital wireless transceiver for transport to a remote receiving transceiver connected to a microprocessor for data logging.

A method of using nanostructured chemicals as alloying agents for the reinforcement of flouropolymer microstructures, including polymer coils, domains, chains, and segments, at the molecular level. Because of their tailorable compatibility with fluorinated polymers, nanostructured chemicals can be readily and selectively incorporated into polymers by direct blending processes. Properties most favorably improved are time dependent mechanical and thermal properties such as heat distortion, creep, compression set, shrinkage, modulus, hardness and abrasion resistance. In addition to mechanical properties, other physical properties are favorably improved, including lower thermal conductivity, fire resistance, and improved oxygen permeability. These improved properties may be useful in a number of applications, including space-survivable materials and creep resistant seals and gaskets. Improved surface properties may be useful for applications such as anti-icing or non-wetting surfaces or as low friction surfaces.

A method for the preparation of an immobilized protein ultrathin film reactor by immersing a solid support alternately into an aqueous solution of protein, and into an aqueous solution of polyion charged oppositely to said protein and preparing a structurally controlled ultrathin film of mono- or multi- protein layers on a said solid support with precision at molecular level. And a method for chemical reaction of a substrate by preparing an immobilized protein ultrathin film reactor composed of multiple layers of protein on a solid support by above mentioned method, and initiating a chemical change of the substrate molecules using obtained immobilized protein ultrathin film reactor.

This invention relates to a method for preparing olivine-type phosphate-series lithium ion battery anode material. The method comprises: mixing one or more of ferrous salt solution, cobalt salt solution and manganese salt solution with oxalic acid or oxalate (precipitating agent) aqueous solution to obtain composite oxalate precursor, uniformly mixing with lithium source and phosphorus source by ball milling, and reacting in inert or weak-reductive atmosphere to obtain olivine-type phosphate-series lithium ion battery anode material. The method utilizes co-precipitation method for metal ion doping, and realizes molecular level uniform mixing among different ions. The obtained olivine-type phosphate-series lithium ion battery anode material has uniform chemical and physical compositions. The average particle size can be controlled within 0.3-10 mu.m. The first charge and discharge cycle specific capacity can reach 150 mAh/g at 0.1 C rate and room temperature. The livine-type phosphate-series lithium ion battery anode material has such advantages as high cycle performance and high charge/discharge performance.

The invention relates to a method for preparing a nano-ferrous lithium phosphate-carbon compound positive material, which is characterized in that based on the ethers organic solvent system and by a sol-process of precursor materials, the mixture at the molecular level of Fe3+, Li+1 and PO42- is realized, and then the technology of low-temperature sintering is used to prepare. Ferrous lithium phosphate in the prepared compound material is in an olivine type with carbon wrapping outside in an amorphous form and the particle size of 45-60nm, and a stable charging and discharging voltage platform at 3.4V is provided, and the charging-discharging capacity under the current of 2C can reach to 133mAh/g. The invention is characterized by simple technique, environment-friendly performance and so on.

The present invention provides a molecular level of DNA information code which uses a base pair sequence as an information code unit. Also, the present invention provides a molecular code system which includes designing and coding DNA which is an information code unit; stabilizing the DNA information code by encapsulating it with an inorganic capsule and coating the DNA-inorganic capsule to a medium; taking and extracting the coated DNA information code which is present in a trace amount, collecting the DNA information code using a polypyrrole-maghemite nanohybrid; and amplifying the collected DNA information code using a polymerase chain reaction and reading the amplified DNA information code. According to the present invention, the DNA information code having high security is prepared by assigning a security unit to a DNA which has an excellent accumulating capacity, and then the DNA information code is stabilized so as to be coated to a medium. Only the DNA information code may be extracted, collected, and read, if necessary. Thus, a unified molecular code system can be established.

The present invention discloses one kind of nanometer composite silica/acrylate emulsion and its preparation process. The present invention is superior to available technology, and the composite emulsion has dispersed nanometer inorganic silica phase in 0.1-5 % of the total weight of monomers for the acrylate copolymer emulsion. The preparation process includes the surface treatment of nanometer inorganic silica phase, and synthesizing nanometer inorganic phase/polymer emulsion in molecular level compounding through in-situ polymerization process or seed emulsion polymerization process. The composite emulsion of the present invention can form film with doubled tensile strength and breaking elongation. Adding nanometer silica in 0.2 % results in tensile strength of 5.25 MPa and breaking elongation of 1300 %.

The invention relates to cosmetic active ingredient-containing lipidosome as well as a preparation method and application thereof. The cosmetic active ingredient-containing lipidosome is small and uniform in particle size, so that the wrapped active ingredients can permeate the cuticles to the deep layer of skin so as to effectively realize deep skin care. Moreover, due to the small particle size, the collision and sedimentation probability of the finished lipidosome product is decreased and the stability of the lipidosome cosmetic is improved. The cosmetic active ingredient-containing lipidosome is prepared by a host-guest chemical method, so that the lipoid molecules and the active ingredient molecules are uniformly mixed on the molecular level, so that the gathering inactivation phenomenon of the active ingredients is avoided; the preparation condition is mild, so that the active ingredients are prevented from damage.

There is provided a diffractive element including a first member 2, which includes a first resin 2a and has a predetermined refractive index, and a second member 3, which has the same refractive index as the first member 2 having the predetermined refractive index in one wavelength of light and has a refractive index different from the first member 2 having the predetermined refractive index in the other wavelength of light. The first member 2 and the second member 3 are alternately arranged within an incidence plane of the two wavelengths of light, thereby constituting a diffraction grating. The second member 3 includes a second resin 3a to dissolve an organic matter 5 having optical absorption in a predetermined wavelength range at a molecular level, whereby the refractive index of the second member 3 is formed.

The invention relates to a method for preparing ethylene rhodanate-epoxy-POSS hybrid resin, which is mainly applied to advanced electronic packaging substrate materials. Heat resistance and dielectric property are hard to be enhanced significantly only by molecular design of epoxide resin at present. Ethylene rhodanate modified epoxy has better heat resistance but unobvious improvement of dielectric property; and dent resistance is greatly affected and moisture absorption is relatively high. The invention adopts unique functionalized hollow polyhedral oligmeric silsesquioxane nanometer oligomer modified epoxy-ethylene rhodanate, thus obtaining the advanced electronic packaging substrate resin with good heat resistance and low dielectric property; the solidified hybrid material has good net-working structure; and the polyhedral oligmeric silsesquioxane is dispersed in the resin substrate at molecular level. The mechanical property of the resin substrate is significantly improved; moreover, the heat resistance, the dielectric property and the moisture absorption property are good. The hybrid resin can be used for a long time at the high temperature of 200 DEG C.

The invention discloses a preparation method of a lithium ion battery negative electrode material spinel porous high-entropy oxide material, and belongs to the field of inorganic oxide powder materials. The method is a low-temperature combustion synthesis method, and specifically includes the steps that metal nitrate is adopted as a metal source, one or a mixture of several of tartaric acid, citric acid, glucose, hexamine and ethylenediaminetetraacetic acid is used as a fuel, and by controlling the concentration of the metal salt raw material, the kind and the amount of the fuel, the kind andthe amount of a combustion improver and an ignition mode, characteristics of the grain size, the shape and the like of spinel ransition metal high-entropy oxide nano-powder are adjusted and controlled. According to the preparation method of the lithium ion battery negative electrode material spinel porous high-entropy oxide material, liquid-phase ingredients are adopted, molecular-level even mixing of the raw materials is ensured, and a stoichiometric ratio of the product is achieved; meanwhile the preparation method of the lithium ion battery negative electrode material spinel porous high-entropy oxide material has the advantages of being energy-saving, high in production efficiency, environmentally friendly, free from complex post-treatment and the like, and the prepared high-entropy oxide powder is high in purity, small in grain size and even in distribution, and has high initial discharge capacity and good cycle performance.

The invention provides a mesoporous tungstate photocatalysis material and a preparation method thereof. According to the invention, metal inorganic salt and alkoxide are used as precursors, and molecular level mixing of metallic elements in a precursor solution is realized through addition of a chelating agent so as to avoid phase separation during evaporation of solvents; the method of an inorganic pore forming agent is used to allow a certain metallic element to be excessive in the process of synthesis and to exceed stoichiometric proportion, a part of the excessive metallic element participates in a reaction in the process of roasting to produce tungstate, and the rest part of the excessive metallic element is precipitated to form metal oxide or salt, functioning as a pore forming agent and stabilizing a meso-structure; the inorganic pore forming agent is removed by using treating methods of acid, alkali, dissolving and the like to obtain the mesoporous tungstate material. The invention has the advantages of a simple synthesis process, no harsh conditions and practicable operation. When applied in indoor air purification, the mesoporous tungstate photocatalysis material obtained in the invention has an obvious effect in removing formaldehyde, with a removal rate up to 92%.