4211 results about "Epoxide" patented technology

Nucleic acids are fixed or immobilized to non-porous solid supports (substrates), and include systems containing such supports and arrays with fixed or immobilized nucleic acids. These compositions are useful for nucleic acid analyses and a host of applications, including, for example, detection, mutational analysis and quantification. The non-porous solid supports can be transparent or translucent, and the surfaces can be treated with agents to fix or immobilize the nucleic acids. Such agents include, for example, amine providing compounds, epoxy compounds and acid solutions. The fixed or immobilized nucleic acids can be unlabeled, or labeled with at least one non-radioactive signaling moiety, such as the case when the nucleic acids are double-stranded.

The invention relates to a two-component epoxy resin adhesive, including the following components: novolac epoxy resin, lipid ring type epoxy resin and terminal carboxylic acrylonitrile butadiene rubber in component A, and 1, 4-di-benzene (2, 4-diaminobenzene oxygen) in component B, wherein, the mass percentage of the lipid ring type epoxy resin is 20-35 percent of the novolac epoxy resin, the mass percentage of the terminal carboxylic acrylonitrile butadiene rubber CTBN is 12 percent of the novolac epoxy resin and the mass percentage of the 1, 4-di-benzene (2, 4-diaminobenzene oxygen) is 15-20 percent of the novolac epoxy resin; and the preparation of the two-component epoxy resin adhesive includes the step of evenly mixing the component A and the component B for use. The two-component epoxy resin adhesive used for conductive adhesive has good heat resistance, average stretching and shearing strength of 21.28MPa, simple preparation process and operation without solvent, and plays the role of protecting environment.

Salen complexes were found to be excellent catalysts for the reaction of terminal epoxides with CO₂ when used in conjunction with a Lewis base cocatalyst (DMAP). This catalyst system cleanly affords the product cyclic carbonates in high yield under mild reaction conditions and is applicable to a variety of terminal epoxides.

Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases. The activities of those Ntn having multiple activities can be differentially inhibited by the compounds described. For example, the chymotrypsin-like activity of the 20S proteasome may be selectively inhibited with the inventive compounds. The peptide-based compounds include at least three peptide units, an epoxide or aziridine, and functionalization at the N-terminus. Among other therapeutic utilities, the peptide-based compounds are expected to display anti-inflammatory properties and inhibition of cell proliferation.

A method for making an article comprising a core material and a coating thereon, the method comprising the steps of:

(a) providing the core material;

(b) applying one or more layers of a crosslinkable polycationic material, wherein the polycationic material is a reaction product of:

(i) an epoxide of formula (I)

wherein X equals bromo, chloro, iodo, or cyano, and R¹, R², R³, R⁴, independently of one another, are selected from the group consisting of hydrogen, linear or branched C₁-C₆-alkyl, and linear or branched C₁-C₆-alkyl which is substituted with halogen, and

(ii) a polymer having repeating units comprising one or more secondary or tertiary amine group(s);

(c) applying one or more layers of a polyanionic material; and

(d) cross-linking the layers of polyelectrolytes formed by steps (b) and (c).

The articles obtainable by the method of the invention have desirable characteristics regarding adherence to the core material, durability, hydrophilicity, and wettability and are thus useful for the manufacture of medical articles such as ophthalmic devices.

The present invention relates to one kind of high activity catalyst for catalyzing and activating CO2 to react with alkane epoxide to synthesize polycarbonate. The high activity catalyst is tetradentate Schiff base metal complex with double function, i. e., it has both electrophlic center originated from the metal ion in the complex and nucleophilic center originated from the quaternary ammonium salt or quaternary phosphonium salt connected to the benzene ring in the complex. The catalyst can catalyze the reaction of CO2 and alkane epoxide effectively to prepare polycarbonate.

A pharmaceutical composition comprising a co-crystal of an API and a co-crystal former; wherein the API has at least one functional group selected from ether, thioether, alcohol, thiol, aldehyde, ketone, thioketone, nitrate ester, phosphate ester, thiophosphate ester, ester, thioester, sulfate ester, carboxylic acid, phosphonic acid, phosphinic acid, sulfonic acid, amide, primary amine, secondary amine, ammonia, tertiary amine, sp2 amine, thiocyanate, cyanamide, oxime, nitrile diazo, organohalide, nitro, s-heterocyclic ring, thiophene, n-heterocyclic ring, pyrrole, o-heterocyclic ring, furan, epoxide, peroxide, hydroxamic acid, imidazole, pyridine and the co-crystal former has at least one functional group selected from amine, amide, pyridine, imidazole, indole, pyrrolidine, carbonyl, carboxyl, hydroxyl, phenol, sulfone, sulfonyl, mercapto and methyl thio, such that the API and co-crystal former are capable of co-crystallizing from a solution phase under crystallization conditions.

The present invention relates a graphene/metal oxide hybrid aerogel, a preparation method and applications thereof, and belongs to the field of nanometer material applications. The hybrid aerogel comprises a graphene network and a metal oxide network, wherein the two networks are mutually wound to form a hybrid aerogel, and the metal oxide network is further a crystalline state. The hybrid aerogel preparation comprises: preparing a graphene oxide organic solution, adding a soluble metal salt and an epoxide to obtain a uniform non-flowing hybrid wet gel, and carrying out drying and charring to obtain the graphene/metal oxide hybrid aerogel. The hybrid aerogel can be used as an energy storage material, an electromagnetic shielding material, a biological enzyme catalysis carrier and a CO2 absorption material, and has wide applications.

The present invention relates to compositions which contain at least one epoxide adduct A having on average more than one epoxide group per molecule, at least one polymer B of the formula (I), at least one thixotropic agent C, based on a urea derivative in a nondiffusing carrier material, and at least one curing agent D for epoxy resins, which is activated by elevated temperature. This composition serves in particular as an adhesive and has an extremely high dynamic resistance to cleavage, in particular at low temperatures. The invention furthermore relates to impact strength modifiers terminated with epoxide groups and of the formula (I). It has been found that these novel impact strength modifiers result in a significant increase in impact strength in epoxy resin compositions, in particular in two-component epoxy resin compositions.

A two part system for producing structural reinforcing adhesives is provided wherein one component containing epoxy resin is combined with a second component containing a specified curative system. An aliphatic polyamine, an amidoamine, an alcohol and an adduct of a polyamine and an epoxide are present in the curative system. When a thermally activated blowing agent is utilized, the resulting foam is remarkably uniform in cell structure and has improved strength and modulus. Hollow inorganic microspheres are employed to reduce the density of the thermoset produced from the two part system.

In one aspect, the present disclosure encompasses polymerization systems for the copolymerization of CO₂ and epoxides comprising 1) a catalyst including a metal coordination compound having a permanent ligand set and at least one ligand that is a polymerization initiator, and 2) a chain transfer agent having two or more sites that can initiate polymerization. In a second aspect, the present disclosure encompasses methods for the synthesis of polycarbonate polyols using the inventive polymerization systems. In a third aspect, the present disclosure encompasses polycarbonate polyol compositions characterized in that the polymer chains have a high percentage of —OH end groups and a high percentage of carbonate linkages. The compositions are further characterized in that they contain polymer chains having an embedded polyfunctional moiety linked to a plurality of individual polycarbonate chains.

The invention discloses a dual-functional catalyst composition and an integrated process for production of olefin epoxides including propylene oxide by catalytic reaction of hydrogen peroxide from hydrogen and oxygen with olefin feeds such as propylene. The epoxides and hydrogen peroxide are preferably produced simultaneously in situ. The dual-functional catalyst comprises noble metal crystallites with dimensions on the nanometer scale (on the order of <1 nm to 10 nm), specially dispersed on titanium silicalite substrate particles. The dual functional catalyst catalyzes both the direct reaction of hydrogen and oxygen to generate hydrogen peroxide intermediate on the noble metal catalyst surface and the reaction of the hydrogen peroxide intermediate with the propylene feed to generate propylene oxide product. Combining both these functions in a single catalyst provides a very efficient integrated process operable below the flammability limits of hydrogen and highly selective for the production of hydrogen peroxide to produce olefin oxides such as propylene oxide without formation of undesired co-products.

Aminoalcohol lipidoids are prepared by reacting an amine with an epoxide-terminated compound are described. Methods of preparing aminoalcohol lipidoids from commercially available starting materials are also provided. Aminoalcohol lipidoids may be prepared from racemic or stereochemically pure epoxides. Aminoalcohol lipidoids or salts forms thereof are preferably biodegradable and biocompatible and may be used in a variety of drug delivery systems. Given the amino moiety of these aminoalcohol lipidoid compounds, they are particularly suited for the delivery of polynucleotides. Complexes, micelles, liposomes or particles containing the inventive lipidoids and polynucleotide have been prepared. The inventive lipidoids may also be used in preparing microparticles for drug delivery. They are particularly useful in delivering labile agents given their ability to buffer the pH of their surroundings.

The invention discloses a method for preparing lignin polyurethane, which comprises the following steps of: using an organic solvent to dissolve the lignin which is extracted and separated from residues after producing ethanol from straws by sodium hydroxide; removing the residues, and depositing the mixture with water; separating the lignin; modifying the lignin with an epoxide; dissolving the lignin into a polylol; and finally compounding the lignin with raw materials of isocyanate and the like to obtain a polyurethane material. The lignin used in the method has high reactivity which can be further enhanced through modification so as to obtain a lignin polyurethane material; the polylol used in the method not only can be used as a solvent but also can take part in a synthetic reaction, has good dissolvability to the lignin, and ensures that undissolved lignin particles cannot appear in a polyurethane foam material; and the link for polyurethane synthesis uses no volatile organic solvents, so the production process causes no pollution to the environment, and simultaneously the cost of a polyurethane product is reduced.

A catalyst, useful for the direct epoxidation of olefins, is disclosed. The catalyst comprises palladium nanoparticles, support nanoparticles, and a titanium zeolite having a particle size of 2 microns or greater. The palladium nanoparticles are deposited on the support nanoparticles to form supported palladium nanoparticles, and the supported palladium nanoparticles are deposited on the titanium zeolite; or the supported palladium nanoparticles are deposited on a carrier having a particle size of 2 microns or greater. The invention also includes a process for producing an epoxide comprising reacting an olefin, hydrogen and oxygen in the presence of the catalyst. The catalysts are more active in epoxidation reactions, while demonstrating the same or better selectivity.

Poly(ester-acrylate) and poly(ester/epoxide) dendrimers. These materials can be synthesized by utilizing the so-called “sterically induced stoichiometric” principles. The preparation of the dendrimers is carried out by reacting precursor amino/polyamino-functional core materials with various branch cell reagents. The branch cell reagents are dimensionally large, relative to the amino/polyamino-initiator core and when reacted, produce generation=1 dendrimers directly in one step. There is also a method by which the dendrimers can be stabilized and that method is the reaction of the dendrimers with surface reactive molecules to pacify the reactive groups on the dendrimers.

An objective of the present invention is to overcome a problem that there is an inverse relationship between the decellularization rate and the strength of tissue. This problem was solved by immersing tissue in a solution containing a non-micellar amphipathic molecule (e.g., a 1,2-epoxide polymer). Thus, the present invention provides decellularized tissue, in which the cell survival rate of the tissue is less than a level at which calcification or an immune reaction is elicited in an organism and the tissue damage rate of the tissue is suppressed to a level which permits clinical applications. Tissue prepared by the above-described treatment preferably retains a certain level of tissue strength. Further, the tissue of the present invention has an effect of performing cell replacement.

Peptide-based compounds including heteroatom-containing, three-membered rings efficiently and selectively inhibit specific activities of N-terminal nucleophile (Ntn) hydrolases associated with the proteasome. The peptide-based compounds include an epoxide or aziridine, and functionalization at the N-terminus. Among other therapeutic utilities, the peptide-based compounds are expected to display anti-inflammatory properties and inhibition of cell proliferation. Oral administration of these peptide-based proteasome inhibitors is possible due to their bioavailability profiles

The invention discloses a preparation method of rare earth-doped double metal cyanide catalyst and a method for preparing low molecular weight poly (carbonic ester-ether) glycol by using the catalyst to catalyze the copolymerization of carbon dioxide and epoxy compounds. The preparation method of poly (carbonic ester-ether) glycol comprises the following steps: using rare earth-doped double metalcyanide based on Zn3[Co(CN)6]2 as a catalyst, and letting carbon dioxide and epoxy compounds be subject to polymerization in the presence of chain transferring agent to obtain the poly(carbonic ester-ether) glycol. According to the invention, compared with the prior art, the rare earth-doped double metal cyanide based on Zn3[Co(CN)6]2 used herein efficiently catalyzes the copolymerization of carbon dioxide and epoxy compounds under the effect of chain transferring agent; and compared with double metal cyanide without doping, the rare earth-doped double metal cyanide based on Zn3[Co(CN)6]2 used herein has higher catalytic activity and better product selectivity.

The invention discloses a preparing method of poly (carbonic ester-ether) polyalcohol. Rare-earth doped bi-metal cyanides based on Zn3[Co(CN)6]2 serve as catalysts, carboxylic acids serve as chain transfer agents, and carbon dioxide and epoxy compounds are performed with a copolymerization reaction to obtain the poly (carbonic ester-ether) polyalcohol. Compared with the prior art, the carboxylic acids serve as chain transfer agents, and due to the fact that the carboxylic acids are strong in coordination capability, faster in chain transfer, capable of restraining continuous inserting of epoxy monomers and free of ether structure, unit content of carbonic ester is improved, and the prepared poly (carbonic ester-ether) polyalcohol has higher carbonic ester unit content. Experimental results indicate that molecular weight of the prepared poly (carbonic ester-ether) polyalcohol is 1500g/mol-5000g/mol, molecular weight distribution is 1.11-1.50, unit content of the carbonic ester is 40%-80%, catalytic activity is larger than 1.0kg/gLn-DMC, and cyclic carbonic ester content is less than 10wt%.

The invention relates to a lithium ion battery composite cathode material and a preparation method. The cathode material comprises a hard carbon precursor material containing hetero atoms, and natural spherical graphite, wherein the hard carbon precursor material selects one or more than two of phenolic resin, polyfurfural, furan resin, polyvinyl alcohol, epoxide resin or polyacrylonitrile as raw materials, and accounts for 5 to 45 percent of the natural spherical graphite by mass; modifier of the hetero atoms is boron-containing modifier including boric acid and diboron trioxide, phosphor-containing modifier including phosphoric acid and phosphorus pentoxide, and nitrogen-containing modifier HNO3; and one of the modifiers accounts for 5 to 35 percent of the hard carbon precursor by mass. An analog battery formed by the cathode material which is prepared by the method has the capacity over 350 mAH/g and first coulomb efficiency up to 95.8 percent, and has good circulation performance. The preparation method has the advantages of low cost and simple process.