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3583 results about "Combined use" patented technology

Verb (used with object), com·bined, com·bin·ing. to bring into or join in a close union or whole; unite: She combined the ingredients to make the cake. They combined the two companies. to possess or exhibit in union: a plan that combines the best features of several other plans. to harvest (grain) with a combine.

Electronic discount couponing method and apparatus for generating an electronic list of coupons

A method and apparatus for distributing, generating, and redeeming discount Virtual Coupons TM , rebate or gift certificates or the like which may be used on conjunction with a frequency card program or the like. Virtual Coupons TM may be distributed electronically, for example, in the form of a diskette or CD-ROM software. Software on the diskette or CD-ROM may prompt a consumer to call a 1-800 number for a validation number or code. During the phone call, telemarketing personnel may request consumer demographic and or identification information which may be entered into a centralized database. Once the software is validated, a consumer may print out a list selected Virtual Coupons TM displayed on a Graphical User Interface (GUI). When a product is purchased, the UPC code of the product may be compared electronically with a list of Virtual Coupons TM authorized for a particular consumer. An appropriate coupon discount may then be applied and the Virtual Coupon TM may be considered "redeemed". Once redeemed, consumer ID information and Virtual Coupon TM information may be retrieved electronically and used to update a central database. Accurate data may then be produced illustrating which consumers or groups of consumers are redeeming which Virtual Coupons TM . Such data may be used for marketing purposes or to generated further diskettes for distribution targeting specific consumers or groups of consumers with specific classes of Virtual Coupon TM offerings. The use of Virtual Coupons TM eliminates or reduces fraud, and allows a frequency card discount to be applied only a limited number of times.

Automatic video system using multiple cameras

A camera array captures plural component images which are combined into a single scene from which “panning” and “zooming” within the scene are performed. In one embodiment, each camera of the array is a fixed digital camera. The images from each camera are warped and blended such that the combined image is seamless with respect to each of the component images. Warping of the digital images is performed via pre-calculated non-dynamic equations that are calculated based on a registration of the camera array. The process of registering each camera in the arrays is performed either manually, by selecting corresponding points or sets of points in two or more images, or automatically, by presenting a source object (laser light source, for example) into a scene being captured by the camera array and registering positions of the source object as it appears in each of the images. The warping equations are calculated based on the registration data and each scene captured by the camera array is warped and combined using the same equations determined therefrom. A scene captured by the camera array is zoomed, or selectively steered to an area of interest. This zooming- or steering, being done in the digital domain is performed nearly instantaneously when compared to cameras with mechanical zoom and steering functions.

Signal processing apparatus

A signal processor which acquires a first signal, including a first primary signal portion and a first secondary signal portion, and a second signal, including a second primary signal portion and a second secondary signal portion, wherein the first and second primary signal portions are correlated. The signals may be acquired by propagating energy through a medium and measuring an attenuated signal after transmission or reflection. Alternatively, the signals may be acquired by measuring energy generated by the medium. A processor of the present invention generates a primary or secondary reference signal which is a combination, respectively, of only the primary or secondary signal portions. The secondary reference signal is then used to remove the secondary portion of each of the first and second measured signals via a correlation canceler, such as an adaptive noise canceler, preferably of the joint process estimator type. The primary reference signal is used to remove the primary portion of each of the first and second measured signals via a correlation canceler. The processor of the present invention may be employed in conjunction with a correlation canceler in physiological monitors wherein the known properties of energy attenuation through a medium are used to determine physiological characteristics of the medium. Many physiological conditions, such as the pulse, or blood pressure of a patient or the concentration of a constituent in a medium, can be determined from the primary or secondary portions of the signal after other signal portion is removed.

Membrane suitable for use in an analyte sensor, analyte sensor, and associated method

A multifunctional membrane is provided. The multifunctional membrane is suitable for use in an analyte sensor. In a particular application, the multifunctional membrane may be used in connection with an amperometric biosensor, such as a transcutaneous amperometric biosensor. Some functions of the membrane are associated with properties of membrane itself, which is comprised of crosslinked polymers containing heterocyclic nitrogen groups. For example, the membrane, by virtue of its polymeric composition, may regulate the flux of an analyte to a sensor. Such regulation generally improves the kinetic performance of the sensor over a broad range of analyte concentration. Other functions of the membrane are associated with functional components, such as a superoxide-dismutating/catalase catalyst, either in the form of an enzyme or an enzyme mimic, that can be bound to the scaffold provided by the membrane. The effect of any such enzyme or enzyme mimic is to lower the concentration of a metabolite, such as superoxide and/or hydrogen peroxide, in the immediate vicinity of the sensing layer of the biosensor. Lowering the concentrations of such metabolites, which are generally deleterious to the function of the sensor, generally protects or enhances biosensor integrity and performance. The membrane is thus an important tool for use in connection with analyte sensors, amperometric sensors, biosensors, and particularly, transcutaneous biosensors. A membrane-covered sensor and a method for making same are also provided.

System and method for providing electrical pulses to the vagus nerve(s) to provide therapy for obesity, eating disorders, neurological and neuropsychiatric disorders with a stimulator, comprising bi-directional communication and network capabilities

A system and method for providing pulsed electrical stimulation to one or both vagus nerve(s) of a patient to provide therapy for obesity, eating disorders, neurological and neuropsychiatric disorders. The electrical pulses can be provided either unilaterally or bilaterally (left and right vagus nerves) and can be supra-diaphramatic or be sub-diaphramatic. The system comprising implantable stimulator, lead(s), an external stimulator, and a programmer. The implantable stimulator, comprising a pulse generator module, and a stimulus-receiver module which is used in conjunction with an external stimulator. Control circuitry ensures selective operation of one of the modules of the implanted stimulator, at a time. Further, the external stimulator comprises a telemetry module for remotely activating (or de-activating) programs over the internet, to arrive at the optimal program for each patient. Once the optimal “dose” is titrated using the external stimulator, the implanted pulse generator can then be programmed to similar parameters. The external stimulator in conjunction with the implanted stimulus-receiver can override the implanted pulse generator module, to provide extra dose of therapy, and also to conserve the implanted battery. The external stimulator is networked to other computers. Using the networking, a physician situated remotely can monitor and program the devices, as well as, automatically generate invoicing. In one embodiment, the external stimulator also comprises GPS circuitry for locating patient.

Application of lipid vehicles and use for drug delivery

InactiveUS7063860B2Reduce and prevent antibody-mediated resistanceIncrease stimulationBiocideAntipyreticAnticarcinogenCapsaicin
The present invention relates to compositions and methods for the administration of lipid-based vehicles to treat various disorders, including bladder inflammation, infection, dysfunction, and cancer. In various aspects, the compositions and methods of the invention are useful for prolonged delivery of drugs, e.g., antibiotics, pain treatments, and anticancer agents, to the bladder, genitourinary tract, gastrointestinal system, pulmonary system, and other organs or body systems. In particular, the present invention relates to liposome-based delivery of vanilloid compounds, such as resiniferatoxin, capsaicin, or tinyatoxin, and toxins, such as botulinum toxin, for the treatment of bladder conditions, including pain, inflammation, incontinence, and voiding dysfunction. Further related are methods of using these vehicles alone or in conjunction with antibodies, e.g., uroplakin antibodies, to improve duration of liposome attachment, and provide a long-term intravesical drug delivery platform. The present invention specifically relates to antibody-coated liposomes that are useful for targeting specific receptors for drug, peptide, polypeptide, or nucleic acid delivery. In one particular aspect, the present invention relates to liposomes coated with antibodies against nerve growth factor (NGF) receptor and containing NGF antisense nucleic acids, which are used as a treatment for neurogenic bladder dysfunction.

Battery pack having memory

In an exemplary embodiment, a battery conditioning system monitors battery conditioning and includes a memory for storing data based thereon; for example, data may be stored representative of available battery capacity as measured during a deep discharge cycle. With a microprocessor monitoring battery operation of a portable unit, a measure of remaining battery capacity can be calculated and displayed. Where the microprocessor and battery conditioning system memory are permanently secured to the battery so as to receive operating power therefrom during storage and handling, the performance of a given battery in actual use can be accurately judged since the battery system can itself maintain a count of accumulated hours of use and other relevant parameters. In the case of a nonportable conditioning system, two-way communication may be established with a memory associated with the portable unit so that the portable unit can transmit to the conditioning system information concerning battery parameters (e.g. rated battery capacity) and/or battery usage (e.g. numbers of shallow discharge and recharge cycles), and after a conditioning operation, the conditioning system can transmit to the portable unit a measured value of battery capacity, for example. A battery pack having memory stores battery history and identifying data to be retrieved by a portable battery powered device. Battery status information may be utilized in conjunction with characteristic battery history data in order to optimize charging and discharging functions and to maximize the useful life of a battery pack.

Technique for using heat flow management to treat brain disorders

A method of treating a brain disorder by heat transfer from brain tissue comprising the steps of surgically cutting a heat transfer aperture into a patient's skull, thereby exposing a predetermined portion of patient's brain; surgically implanting into said heat transfer aperture a heat pump having one or more electrical sensor elements and one or more temperature sensor elements; surgically implanting a heat transfer management unit in a body cavity of said patient such that a micro controller of the heat transfer management unit is connected to one or more activity sensor elements and one or more temperature sensor elements contacting brain tissue and connecting the heat transfer management unit to said heat pump via a lead bundle. Optionally, the heat transfer unit may be located external to the patient's body. Responsive to signals from one or more activity or temperature sensor elements, mathematical algorithms of the heat transfer management unit determine abnormal brain activity, causing the heat pump to remove heat from the brain tissue into a heat sink, thereby cooling the predetermined portion of the patient's brain. This technique utilizes acute hypothermia by means of a Peltier cooler or similar device to cool the brain temperature to reduce or prevent seizure initiation and/or propagation. The method may be used in association with brain stimulation and/or drug application to acutely avoid the occurrence of a seizure episode.

Personal choice biometric signature

A biometric method and system for personal authentication using sequences of partial fingerprint signatures provides a high security capability to various processes requiring positive identification of individuals. This approach is further enhanced by employing a frequency domain technique for calculating a Similarity Index of the partial fingerprint signatures. In a baseline usage, the sequential partial fingerprint sequence techniques augments sentinel systems for gaining access to restricted areas, and when used in combination with financial cards, offer a unique and greatly simplified means for authenticating or identifying individuals. A highly automated technique initially obtains a reference set of linear partial fingerprint signatures which serve as reference data against which later proffered candidate data in the form of at least two linear partial fingerprint signatures are compared for authentication. The particular two candidate signatures used and the sequence in which they are submitted are selected with the user's consent and serve as a PIN-like unique personal code. In an advanced embodiment, a pair of proximity sensors located along each of the linear tracks used for developing the linear partial signatures produce finger sensing signals which compensate for finger movement speeds and hence significantly improves the calculated Similarity Index values. The use of only partial fingerprint data greatly allays the concerns of widespread fingerprint dissemination by many individuals.

Photo Automatic Linking System and method for accessing, linking, and visualizing "key-face" and/or multiple similar facial images along with associated electronic data via a facial image recognition search engine

The present invention provides a system and method for input of images containing faces for accessing, linking, and or visualizing multiple similar facial images and associated electronic data for innovative new on-line commercialization, medical and training uses. The system uses various image capturing devices and communication devices to capture images and enter them into a facial image recognition search engine. Embedded facial image recognition techniques within the image recognition search engine extract facial images and encode the extracted facial images in a computer readable format. The processed facial images are then entered for comparison into at least one database populated with facial images and associated information. Once the newly captured facial images are matched with similar “best-fit match” facial images in the facial image recognition search engine's database, the “best-fit” matching images and each image's associated information are returned to the user. Additionally, the newly captured facial image can be automatically linked to the “best-fit” matching facial images, along with comparisons calculated, and/or visualized. Key new use innovations of the system include but are not limited to: input of user selected facial images for use finding multiple similar celebrity look-a-likes, with automatic linking that return the look-a-like celebrities' similar images, associated electronic information, and convenient opportunities to purchase fashion, jewelry, products and services to better mimic your celebrity look-a-likes; health monitoring and diagnostic use by conveniently organizing and superimposing periodically captured patient images for health professionals to view progress of patients; entirely new classes of semi-transparent superimposed training your face to mimic other similar faces, such as mimic celebrity look-a-like cosmetic applications, and or facial expressions; intuitive automatic linking of similar facial images for enhanced information technology in the context of enhanced and improved organization, classification, and fast retrieval objects and advantages; and an improved method of facial image based indexing and retrieval of information from the web-crawler or spider searched Web, USENET, and other resources to provide new types of intuitive easy to use searching, and/or combined use with current key-word searching for optimized searching.

System, method, and computer program product for selecting and presenting financial products and services

A method and apparatus are provided for automatically preparing a client communication pertaining to a financial product for a client, wherein the client communication is for combined use with a corresponding host vehicle. The method comprises providing a format for the client communication wherein the communication format includes a variable portion; inputting into a computer-accessible storage medium variable information other than a client identification; inputting into the storage medium decision information; and using the decision information to select a subset of the variable information for inclusion in a variable portion of the client communication corresponding to the variable portion of the client communication format. The apparatus comprises an inputting device for inputting into a computer-accessible storage medium variable information comprising other than a client identification and decision information; a processor operatively coupled to the storage medium for using the decision information to automatically select a subset of the variable information for each of the clients; and an output preparing component in operative communication with the processor for preparing the client communications and for automatically inserting into the client communication the subset of variable information for the corresponding and respective client.
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