365 results about "Lung" patented technology

Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially an organ such as a lung, by adjusting pressure as needed to maintain a constant pressure within the organ even during external pressure fluctuations due, for example, to transportation of the organ in an airplane. Gas passing into and out of the organ may be conditioned to prolong tissue viability.

The invention relates to the technical field of atomization rate control, in particular to an intelligent atomization compliance monitoring method and system for children. The method comprises the following steps: firstly, acquiring expiration flow velocity, inspiration flow velocity and multi-direction motion acceleration time sequence data of a child in a historical monitoring period, and reflecting breathing and behavior action conditions; dynamically analyzing the numerical characteristics of the expiration flow velocity and the inspiration flow velocity to divide a respiratory cycle, and analyzing the cycle length, the inspiration flow velocity cumulant and the like to construct a respiratory characteristic vector; screening a target monitoring period based on the breathing feature vector and the period number similarity; further analyzing the motion acceleration change and accumulation characteristics in the target monitoring period, and quantifying the behavior compliance expression degree; the behavior compliance expression degree and the breathing feature vector are deeply fused, a'breathing state-behavior cooperation 'joint evaluation model is established, the breathing and behavior states of children are dynamically recognized, the medicine atomization rate is accurately adjusted, and effective deposition of lung medicine is improved.

The invention provides a lung function compensation mechanism dynamic quantitative analysis method combining partition impedance measurement and a machine learning algorithm, and the method comprises the steps: obtaining a corresponding relation between a ventilation dynamic sequence and a blood flow characteristic value, and enabling the ventilation dynamic sequence and the blood flow characteristic value to be aligned in a time dimension through a multi-dimensional data fusion technology, constructing a joint feature matrix reflecting the breathing process change and the blood flow state to obtain a time-space synchronization feature set; expanding the three-dimensional dynamic model according to a time axis by adopting a data visualization technology through a compensation state quantification result, extracting a key frame from linkage change of a ventilation state value and a blood flow characteristic value, and generating a dynamic representation sequence reflecting a lung function compensation process; and obtaining a dynamic representation sequence, carrying out grouping analysis on individual differences in the sequence by utilizing a clustering algorithm, extracting a characteristic mode related to disease dynamics from a grouping result, and obtaining final lung function compensation quantitative representation data.

The application belongs to the technical field of animal models for basic scientific research, and particularly relates to a method for establishing an acute lung injury animal model, which comprises the following steps: sending a podophyllotoxin or a podophyllotoxin reagent into a rat body through oral administration or intragastric perfusion to obtain the acute lung injury animal model. The method for establishing the acute lung injury animal model provided by the application uses the podophyllotoxin as an inducer for establishing a mouse acute lung injury model, and the mouse can orally take or intragastrically perfuse the podophyllotoxin to achieve the method, without needing a special medicine injection device, so that the method is simple in medicine taking, few in experimental steps, and does not need complex surgical operations.

The invention provides a lung expiration training system for nursing a patient outside a chest, which relates to the technical field of medical rehabilitation training and comprises a respiratory signal acquisition module, a main control and signal processing module, a feedback and excitation module and a data management and scheme customization module, the respiratory signal acquisition module is used for acquiring an instantaneous pressure difference signal in the expiration process of a patient in real time by utilizing a differential pressure type flow sensor; the main control and signal processing module converts the pressure difference signal into instantaneous flow, obtains an expiration flow-time curve, a primary expiration amount and expiration efficiency based on discrete sampling, smooth operation and integral calculation, and calculates an error sum of squares and a curve goodness of fit to form a comprehensive control amount; the feedback and excitation module provides visual, auditory or tactile feedback according to the comprehensive control quantity, and can present a gamification interface to guide the patient to adjust the breathing rhythm; the data management and scheme customization module is used for setting a personalized training scheme and recording training data, and the trend analysis unit generates a rehabilitation trend report based on historical indexes.

The invention belongs to the technical field of medical instruments. In order to solve the problems that an existing lung function detection device is low in detection result accuracy and cannot detect parameters such as the residual gas amount, the device for assisting in detecting the lung function of the chronic obstructive pulmonary disease patient is provided and comprises a detection device, a helium bottle, a sealing mask, a nose clip, an air suction pipe, an air outlet pipe, a sealing unit and a plugging switching mechanism; one end of the air suction pipe is connected with the helium tank, and the other end is connected with the plugging switching mechanism; one end of the air outlet pipe is connected with the detection device, and the other end is connected with the plugging switching mechanism; the nose clip is arranged at the upper end of the sealing mask. According to the embodiment of the invention, a subject cannot inhale external air and cannot exhale in-vivo air from the nasal cavity through the nasal clip, and the plugging switching mechanism can thoroughly open the pipe orifice of the air outlet pipe or the air inlet pipe, so that the subject can inhale or exhale easily, the detection accuracy is high, and the detection efficiency is high. And the method can be combined with a closed helium dilution method to obtain parameters such as residual gas amount.

The present disclosure provides methods of treating pulmonary fibrosis, the methods comprising administering taladegib to a subject in need thereof.

The utility model discloses a rehabilitation training device for nursing chronic obstructive pulmonary disease, a pedaling device comprises a mounting frame and a linkage assembly, and the mounting frame is arranged on the other side of a support frame; the linkage assembly is rotatably arranged in the mounting frame; the breathing device comprises a breathing box, a breathing assembly, a hose and a mask, and the breathing box is arranged on one side of the top of the mounting frame; the breathing assembly is arranged in the breathing box, and the breathing assembly is connected with the linkage assembly; one end of the hose is connected with the breathing assembly; the mask is connected with the other end of the hose; the control system comprises a microprocessor, and the microprocessor is arranged in the breathing box and connected with the breathing assembly. Therefore, the device combines pedaling and breathing training, strengthens lower limb strength and improves the breathing function, the linkage assembly ensures synchronization of the pedaling and breathing training, the training effect is improved, the built-in control system monitors breathing in real time, the training intensity is automatically adjusted, safety and comfort are guaranteed, and the training effectiveness and patient compliance are improved.

Methods and apparatuses for performing automated detection of lung slide using a computing device (e.g., an ultrasound system, etc.) are disclosed. In some embodiments, the techniques determine lung sliding using one or more neural networks. In some embodiments, the neural networks are part of a process that determines probabilities of the lung sliding at one or more M-lines. In some embodiments, the techniques display one or more probabilities of lung sliding in a B-mode ultrasound image.

The invention belongs to the technical field of lung rehabilitation training, and particularly relates to a lung rehabilitation training effect evaluation system and method based on multi-modal data fusion. According to the method, a dynamic reference model conforming to individual differences is established through three-dimensional pulmonary respiration mobility modeling based on patient CT images, individualized comparative analysis of lung function recovery states of different patients is achieved, and meanwhile external respiration dynamics and internal physiological state parameters are collected and fused; rehabilitation quality is evaluated from the two aspects of exercise performance and physiological response, scientificity and reliability of evaluation are remarkably improved, a patient can visually perceive difference between own breathing actions and an ideal state through AR visual correction prompts, active correction of actions and muscle memory formation are promoted, effectiveness of rehabilitation training is improved, and the rehabilitation training effect is improved. The training difficulty and the resistance threshold value are dynamically adjusted according to the historical evaluation result and the real-time correction effect, it is guaranteed that rehabilitation training is gradually strengthened within the safe and reasonable range, and the rehabilitation efficiency is improved.

The present disclosure provides methods of treating pulmonary fibrosis, the methods comprising administering taladegib to a subject in need thereof.

The invention relates to the technical field of medical instrument testing, and particularly provides a one-way performance testing device and method of a one-way valve, the testing device comprises a device body, the device body comprises a first container, a circulating breathing mechanism, a lung simulation mechanism, a placement mechanism and a data acquisition mechanism; a sealing cover capable of being opened and closed is arranged on the first container; the circulating breathing mechanism comprises a driving assembly and an air pressure change assembly which are connected, and the driving assembly is communicated with the first container; the lung simulation mechanism comprises a second container made of an elastic material and a first air pump, the second container is arranged in the first container, and the first air pump is communicated with the second container to inflate the second container; the placing mechanism is communicated with the second container through a pipeline, and a switch valve is arranged on the pipeline; the data acquisition mechanism comprises at least one pair of flow sensors arranged at the two ends of the placement mechanism to obtain instantaneous ventilation data at the two ends of the one-way valve. The performance of the one-way valve can be conveniently and accurately tested.

The invention provides a breathing mode analysis method and device based on a calm breathing pressure difference waveform and electronic equipment, and relates to the technical field of medical signal processing and artificial intelligence, and the method comprises the following steps: obtaining a calm breathing pressure difference original signal of a target user; preprocessing the calm breathing pressure difference original signal to obtain a target waveform sequence; performing feature extraction based on the target waveform sequence to obtain a plurality of dimension features; combining the at least two dimension features to obtain a multi-modal feature; and inputting the multi-modal features into a trained classification model, and outputting a breathing pattern classification result. According to the method, the whole analysis process is completely based on natural calm breathing, special cooperation or forced breathing actions of the user are not needed, the pain point that traditional lung function examination has a high requirement for the user cooperation degree is solved, and auxiliary decision making of chronic respiratory diseases is achieved.

The invention relates to a control method of auxiliary breathing equipment, a controller, equipment and a storage medium. The auxiliary breathing equipment comprises a first cavity, a second cavity, a pipeline assembly and a gas driving assembly. The method comprises the following steps: periodically acquiring detection information of intra-pulmonary pressure during the period of providing ventilation support by the auxiliary breathing equipment; in response to the fact that the detection information of the intra-pulmonary pressure exceeds a preset pressure range, pressure reduction operation or pressure increase operation is executed to adjust the intra-pulmonary pressure to be within the preset pressure range; the decompression operation comprises the steps that the pipeline assembly and the gas driving assembly are controlled, so that redundant gas in the lung is exhausted to the external environment through the second cavity in the process of maintaining partial gas circulation of the lung between the first cavity and the lung; the pressurization operation comprises the steps that the pipeline assembly and the gas driving assembly are controlled, so that gas of the breathing gas source is introduced into the lung through the first cavity in the process of maintaining partial gas circulation of the lung between the second cavity and the lung. The safety of ventilation support can be improved.

The invention provides a self-adaptive control method and device for a double-ventricle auxiliary system. The method comprises the steps that target aortic pressure detected by a first pressure sensor, target left ventricular end diastolic pressure detected by a second pressure sensor, target right atrial pressure detected by a third pressure sensor and target pulmonary artery pressure detected by a fourth pressure sensor are obtained; and determining a strategy for adjusting the left ventricular assist device or the right ventricular assist device according to the target left ventricular end diastolic pressure, the target right ventricular pressure and the target pulmonary arterial pressure when the peripheral perfusion of the target user is insufficient or the lung is over-perfused. The pressure sensors are arranged to detect the pressure of the inlets and the outlets of the left ventricular assist device and the right ventricular assist device, whether adverse events such as peripheral insufficiency or pulmonary hyperperfusion occur to a user or not is judged according to the detected pressure, and then the adverse events are relieved or even solved by adjusting the rotating speeds of the left ventricular assist device and the right ventricular assist device. And the safety of the user is greatly improved.

The present invention relates to an operating method of a lung monitoring system operated by at least one processor, the operating method comprising the steps of: acquiring a plurality of electrical impedance tomography (EIT) images of the chest of a patient and a plurality of respiratory sound intensity images generated on the basis of respiratory sound signals acquired from the chest of the patient; mapping, on the basis of a plurality of pieces of respiratory interval information acquired by binning a respiratory signal of the patient, an EIT image and a respiratory sound intensity image corresponding to each respiratory interval to each other; and inputting, into a respiratory anomaly prediction model, at least one pair of the EIT image and the respiratory sound intensity image included in each respiratory interval, to acquire a prediction result for respiratory anomalies of the patient.

The present application belongs to the technical field of medicine preparation, and relates to application of a blood-nourishing oral liquid in preparation of medicine for improving blood oxygen saturation. The blood-nourishing oral liquid can improve blood oxygen saturation, improve hypoxemia, improve lung function, and has a preventive and / or therapeutic effect on lung injury, especially acute lung injury.

The application discloses a lung function, respiratory muscle function determination method, system and device, and relates to the technical field of medical detection.The application comprises: MR image data collection, MR image data preprocessing, forming an image data set by MR post-processing image data; dividing the image data set into a training set, a verification set and a test set according to a ratio of 5:2:1; and constructing a UNet segmentation model and training the model by using the image data set.The application innovatively adopts a deep learning method to post-process chest MRI dynamic images, obtains quantitative indexes capable of comprehensively evaluating diaphragm structure and function of hemodialysis patients, and quantitatively describes the diaphragm function condition of the population, thereby making up for the shortcomings that a lung function instrument cannot early identify patients with relatively light respiratory muscle lesions and lung function in a compensatory stage, cannot indicate the position of respiratory muscle lesions, and cannot monitor the lung function of patients with poor lung function due to the inability to complete the lung function instrument examination.

A heart-lung stop prediction device includes: right and left sound detection sections for detecting sounds generated by heartbeat fluctuation at right and left corneal wind sites, respectively, and detecting sounds generated by breathing fluctuation at the right and left corneal wind sites, respectively; a calculation section for calculating a stress index of a mammal based on the sounds generated by heartbeat fluctuation and the sounds generated by breathing fluctuation detected by the right and left sound detection sections; a prediction section for predicting a heart-lung stop period of the mammal based on the stress index calculated by the calculation section; and a notification section for notifying the heart-lung stop period predicted by the prediction section.

An extracorporeal circulation system (10) is provided with: a holder unit (12) integrally having a holder part (18) to which an artificial lung (100) is attached, and a pump drive part (20) for rotating a blood pump (110); and an input part (67) provided separately from the holder unit (12). The holder unit (12) has a pump control part (52) that controls the pump drive part (20) on the basis of information from a sensor for measuring physical property parameters in the circuit and information from the input part (67).

Breathing apparatus for diving comprising one or more air tanks (5), a mouthpiece (1), an electronic control unit (7), a set of valves (2), and a counterlung (6). The control unit (7) is configured to open and close the valves so that the exhaled air is stored and extracted from the counterlung (6) at least once before being discarded. Preferably, the number of times depends on the depth.

The present disclosure provides a method for producing lung mesenchymal cells that can be used as feeder cells in induction of alveolar epithelial cells. A method for producing lung mesenchymal cells of the present disclosure includes culturing mesodermal cells in a presence of a mesenchymal cell-inducing factor, KGF, and FGF 10 so as to induce differentiation of the mesodermal cells into lung mesenchymal cells.

The utility model discloses a medical respiratory medicine vital capacity training device, and relates to the technical field of vital capacity training, in particular to a box body, an air bag is arranged in the box body, a lifting plate is connected in the box body in a sliding mode, four fixing shells are fixedly connected to the top of the lifting plate, and a plurality of balancing weights are arranged in the fixing shells. Supporting plates are slidably connected into the box body, a filtering box is arranged between the two supporting frames, and a first air connector is fixedly connected to the side face of the filtering box. According to the vital capacity training device, cross infection between patients is reduced, and the problems that according to an existing vital capacity training device, an air blowing opening is inconvenient to replace, peculiar smell of air exhaled by the patients cannot be adsorbed, and follow-up training use of the patients is affected are solved.

The invention belongs to the technical field of medical instruments, and discloses a lung leakage postoperative nursing device. Comprising a plurality of sections which are connected in series in a hinged mode. The driving part is fixedly connected with the fixed frame at the end part, and a first knocking part is arranged in each section of fixed frame. The driving part is connected with a rotating rod, the outer side of the rotating rod is fixedly connected with a striking block, the first striking part is located on the rotating track of the striking block, the rotating rod is provided with multiple sections, and each section of the rotating rod is rotationally arranged in different fixing frames. Gaps are reserved between every two sections of rotating rods, and the rotating rods are rotationally connected with connecting rods so that the rotating rods can swing to adjust the angle. The problems that in the prior art, sputum excretion equipment usually knocks the back of a patient or the whole chest of the patient in a wearable mode, puncture points of the patient are injured, and the illness state of the patient is aggravated are solved.

The invention discloses a pitch angle determining device and a pitch angle determining method. The determining device comprises a rotation driving module, a rotatable module, a rotation sensing module, an oscillation measuring module and a control module, the rotation driving module is respectively connected with the rotatable module and the control module, and controls the rotatable module to rotate according to a rotation control signal provided by the control module; the rotation sensing module is used for sensing rotation information of the rotatable module and transmitting the rotation information to the control module; the oscillation measurement module comprises a breathing connection unit and an oscillation measurement unit which are connected; the interface of the breathing connection unit is arranged in the rotatable module; the oscillation measuring unit is electrically connected with the control unit and is used for transmitting the breathing parameters of the sample to be measured to the control unit; the control unit determines the pitching angle of the rotatable module matched with the to-be-tested sample according to the rotation information and the breathing parameters. By adopting the scheme, the pitch angle of the to-be-measured sample is controlled and extracted, accurate measurement of the oscillation lung function is realized, and the problem of measurement errors of different pitch angles is solved.

The utility model provides a blocking valve and a lung function detector, the blocking valve is used for the lung function detector, the blocking valve comprises a valve seat and a blocking device, the valve seat is provided with a hollow cavity, and one end of the valve seat is used for being connected with a collecting device of the lung function detector; the plugging device comprises a fixing seat and a plugging assembly, and the plugging assembly is connected with the fixing seat. The fixed seat is connected with the other end of the valve seat, and the plugging assembly is movably arranged in the hollow cavity; at least part of the fixed seat extends into the hollow cavity; a locking hole is formed in one of the outer wall of the fixing base and the inner wall of the valve seat, an elastic structure is arranged on the other one of the outer wall of the fixing base and the inner wall of the valve seat, and the elastic structure is used for being elastically clamped with the locking hole. According to the blocking valve and the lung function detector provided by the invention, interruption of a lung function test caused by misoperation of a user can be reduced, so that the test efficiency of the lung function detection of the user can be improved.

The application relates to a method for constructing a rat model of chronic obstructive pulmonary disease (COPD) related pulmonary arterial hypertension and application thereof, and belongs to the technical field of animal disease model construction. The method selects 6-8-week-old, 220+ / -10g healthy male SD rats, and all the rats are adaptively fed in a standard SPF level animal room for 7 days; then the rats are divided into a Con group and a COPD-PH group; the rats in the COPD-PH group are given 1mg / mL lipopolysaccharide by airway instillation on the first day and the 14th day; the rats are placed in a self-made whole-body inhalation smoking box for 1h every day from the 2nd day to the 13th day and from the 15th day to the 30th day; the rats enter a low-oxygen box for 8h every day during the light period from the 2nd day to the 13th day and from the 15th day to the 30th day; the rat model can simultaneously reproduce the characteristics of COPD and typical changes of pulmonary arterial hypertension, the right ventricular systolic pressure can be stably increased to 40-50mmHg, the right ventricular hypertrophy index can reach 0.40-0.50, the pulmonary vascular remodeling and inflammation are significant, and various indexes are stable and good in repeatability.

Provided is a new ventilator that can be used for pulmonary resuscitation without requiring an electrical driving source. A ventilator includes a housing. The housing has an input port through which a gas is introduced into the housing, a main port through which the gas that is to be sent to and inhaled by a patient and a gas that is exhaled by the patient pass, an exhaust port through which the gas inhaled or the gas exhaled is exhausted from the housing, a ventilation path connecting the input port and the main port to each other, and a relief valve that is opened by receiving a pressure from the ventilation path and that allows communication between the ventilation path and the exhaust port so as to release the pressure.

This utility model provides a pulmonary function rehabilitation and physiotherapy device for respiratory medicine, relating to the field of respiratory medicine. It includes a main body shell and a protective cover. A U-shaped insert is fixedly connected to one side of the protective cover, and the U-shaped insert is inserted into the inner wall of a positioning shell. The positioning shell is fixedly connected to one side of the main body shell. A linkage rod is slidably connected to the inner wall of the positioning shell. One end of the linkage rod is fixedly connected to a limit block, and a first resilient spring is fixedly connected to one side of the limit block. One end of the first resilient spring is fixedly connected to the inner wall of the positioning shell. This application, through the arrangement of the main body shell, protective cover, U-shaped insert, positioning shell, linkage rod, limit block, first resilient spring, and external pull plate, effectively achieves the purpose of protecting the air blowing mask, solving the problem that prolonged exposure of the air blowing mask to air can affect its normal use due to external factors, greatly improving the practicality of the rehabilitation and physiotherapy device.

Described herein are a system and a method for automatically guiding and evaluating a user's performance during structured breathing exercise sessions. The system retrieves predetermined breathing patterns, including sequences of inhales, exhales, and breath-holds across one or more rounds. Each round includes at least two stages: a breath-hold stage and a first full breath stage immediately following the breath-hold. The system provides real-time guidance through sensory cues, receives user-initiated or automatic signals marking stage transitions, records the duration of each stage, and determines ideal or target durations. A longer first full breath duration indicates improved breath-hold performance and reduced stress. The system generates a final score for each round by combining breath-hold and first full breath durations, reflecting performance, relaxation, lung function, tolerance metrics, and the like. Aggregate session scores are computed across rounds, offering insights into exercise suitability, session effectiveness, and physiological adaptation over time.