764 results about "Lung function" patented technology

The present invention relates to the field of ambulatory and non-invasive monitoring of a plurality of physiological parameters of a monitored individual. The invention includes a physiological monitoring apparatus with an improved monitoring apparel worn by a monitored individual, the apparel having attached sensors for monitoring parameters reflecting pulmonary function, or parameters reflecting cardiac function, or parameters reflecting the function of other organ systems, and the apparel being designed and tailored to be comfortable during the individual's normal daily activities. The apparel is preferably also suitable for athletic activities. The sensors preferably include one or more ECG leads and one of more inductive plethysmographic sensor with conductive loops positioned closely to the individual to preferably monitor at least basic cardiac parameters, basic pulmonary parameters, or both. The monitoring apparatus also includes a unit for receiving data from the sensors, and for storing the data in a computer-readable medium. The invention also includes systems comprising a central data repository for receiving, storing, and processing data generated by a plurality of physiological monitored apparatus, and for making stored data available to the individual and to health care providers.

A system and method can be used to denervate at least a portion of a bronchial tree. An energy emitter of an instrument is percutaneously delivered to a treatment site and outputs energy to damage nerve tissue of the bronchial tree. The denervation procedure can be performed without damaging non-targeted tissue. Minimally invasive methods can be used to open airways to improve lung function in subjects with COPD, asthma, or the like. Different sections of the bronchial tree can be denervated while leaving airways intact to reduce recovery times.

An apparatus and method for measuring the key elements of human primary health is disclosed. The apparatus is in the form of a medical diagnostics unit capable of measuring Electrocardiogram (ECG), height, weight, body mass index (BMI), body temperature, hearing efficiency, lung function, pulse, blood oxygen levels, blood pressure, urology and vision testing. The medical diagnostics unit includes an enclosure with a data card and/or fingerprint entry. The enclosure includes medical measuring devices which allow a patient to follow instructions on a touch screen visual display unit to conduct the desired tests and obtain the patient's health information. This information is stored locally as well as being transmitted to a doctor for review and evaluation. The automated medical diagnostics unit reduces the staffing requirements to obtain a patient's basic health information.

A device for determining the level of nitric oxide in an exhaled airstream belonging to a living organism selected to have its lung function evaluated, where an initial device is arranged to determine the current portion of nitric oxide and/or the distribution of nitric oxide over time during an exhalation phase. During the commencing period of the exhalation phase, the exhaled air is arranged to pass with no or with only a very small resistance or back-pressure to a free space, and during the remaining period, the exhaled air is arranged to pass through the initial device against the action of a suitable resistance or back-pressure. The level of nitric oxide is measured during this remaining period.

A screening method can be used to determine whether a subject is a suitable candidate for interventional therapy. The method can be used to determine the likelihood the subject will receive a therapeutic effect from denervation therapy. The determination is based, at least in part, on lung information obtained by performing lung function tests with and without treating the subject's lungs with a test agent. Based on the response to a test agent, the subject's response to a therapy is predicted.

A method of deformable image registration for thoracic 4-D computed tomography (CT) images includes: receiving, by a processing device, a set of thoracic 4-D CT images; and iteratively solving, by the processing device, an energy function applied to subsequent images of the set of thoracic 4-D CT images to transform the subsequent images into respective optical flow fields between the subsequent images, the energy function enforcing the following constraints on the subsequent images: intensity constancy; mass conservation; gradient constancy; and spatio-temporal smoothness. A method of determining regional lung function includes: receiving, by a processing device, a set of thoracic 4-D CT images of a lung; transforming, by the processing device, the set of 4-D CT images of the lung into respective spatial voxel-wise deformation maps; and transforming, by the processing device, the spatial voxel-wise deformation maps into respective spatial voxel-wise strain maps of the lung indicating regional mechanics of the lung.

An isolated heart or heart-lung preparation in which essentially normal pumping activity of all four chambers of the heart is preserved, allowing for the use of the preparation in conjunction with investigations of electrode leads, catheters, ablation methods, cardiac implants and other medical devices intended to be used in or on a beating heart. The system can be designed to be used within a Magnetic Resonance Imaging (MRI) unit or a X-ray computed tomography (CT) scanner. The preparation may also be employed to investigate heart and lung functions, in the presence or absence of such medical devices. In order to allow comparative imaging visualizations of either or simultaneously the heart and/or lung structures and devices located within the chambers of the heart or vessels or bronchi within the lungs, a clear perfusate such as a modified Krebs buffer solution with oxygenation is circulated through all four chambers of the heart and thus the coronary and/or pulmonary vasculatures. A ventilator with intubation tube can be used to inflate/deflate the lungs and/or provide oxygen to the isolated organs. The preparation and recordings of the preparation may be used in conjunction with the design, development and evaluation of devices for use in or on the heart and/or lungs, as well as for use as an investigational and teaching aid to assist physicians and students in understanding the operation of the cardiopulmonary system.

The invention provides systems and methods for exchanging gas in a microfluidic device, and methods for preparing such microfluidic devices. The systems and methods can be used to transfer oxygen to blood to assist lung function in a patient.

A personal lung function monitoring device capable of exhaled breath analysis is described. The personal lung function monitoring device includes a physical measuring device and a microcontroller. This physical measuring device further includes a flow chamber configured to receive a flow of exhaled breath from a patient/user, and a set of sensors integrated with the flow chamber. The set of sensors can be used to measure a set of properties of the exhaled breath, which can include one or more common lung function parameters and/or one or more biomarkers of the exhaled breath. The microcontroller is coupled to the physical measuring device and configured to receive analog sensor signals from the set of sensors and transmit the digitized sensor signals to a mobile device. In one embodiment, the personal lung function monitoring device combines peak expiratory flow, spirometry, and exhaled breath biomarker measurements into a single device.

The invention relates to patient monitoring systems for monitoring cardiopulmonary function etc. by means of capacitive measurements. Furthermore, the invention relates to a method for monitoring cardiopulmonary function etc. by means of capacitive measurements. In order to provide a reliable technique for monitoring cardiopulmonary function etc., which is particularly suitable for home use, a patient monitoring system (1) for monitoring cardiopulmonary function etc. by means of capacitive measurements is proposed, said system (1) comprising a matrix (3) Many electrodes (2) arranged in the form, said electrodes (2) are suitable for being integrated with the bed (4) etc., each electrode (2) is individually selectable; ) etc., for determining the number of electrodes (2) by determining the capacitance of many electrodes (2); and for selecting a number of said The measured electrodes (2) and means (5) for performing capacitive measurements.

The present invention provides methods and compositions to treat fibrotic conditions, to increase lymphocyte production in vivo, and to improve and/or normalize lung function, pulmonary compliance, blood oxygenation, and blood pH to inhibit inflammatory processes to stimulate or inhibit pro-inflammatory and immune cells, and to inhibit migration of vascular endothelial cells. The invention contemplates the administration of human uteroglobin, native or recombinant, as a means of achieving these ends. Specifically, it has been found that uteroglobin inhibits cell adhesion to fibronectin, increases lymphocyte production in vivo, and improves and/or normalizes lung function, pulmonary compliance, blood oxygenation, and blood pH, and inhibits inflammatory process. In addition it has been found that uteroglobin can stimulate or inhibit pro-inflammatory and immune cells and inhibitor migration of vascular endothelial cells.

The present invention provides methods and compositions to treat fibrotic conditions, to increase lymphocyte production in vivo, and to improve and/or normalize lung function, pulmonary compliance, blood oxygenation, and blood pH to inhibit inflammatory processes to stimulate or inhibit pro-inflammatory and immune cells, and to inhibit migration of vascular endothelial cells. The invention contemplates the administration of human uteroglobin, native or recombinant, as a means of achieving these ends. Specifically, it has been found that uteroglobin inhibits cell adhesion to fibronectin, increases lymphocyte production in vivo, and improves and/or normalizes lung function, pulmonary compliance, blood oxygenation, and blood pH, and inhibits inflammatory process. In addition it has been found that uteroglobin can stimulate or inhibit pro-inflammatory and immune cells and inhibitor migration of vascular endothelial cells.

The present invention provides methods and compositions to treat fibrotic conditions, to increase lymphocyte production in vivo, and to improve and/or normalize lung function, pulmonary compliance, blood oxygenation, and blood pH to inhibit inflammatory processes to stimulate or inhibit pro-inflammatory and immune cells, and to inhibit migration of vascular endothelial cells. The invention contemplates the administration of human uteroglobin, native or recombinant, as a means of achieving these ends. Specifically, it has been found that uteroglobin inhibits cell adhesion to fibronectin, increases lymphocyte production in vivo, and improves and/or normalizes lung function, pulmonary compliance, blood oxygenation, and blood pH, and inhibits inflammatory process. In addition it has been found that uteroglobin can stimulate or inhibit pro-inflammatory and immune cells and inhibitor migration of vascular endothelial cells.

The present invention provides an inhaler capable of measuring lung function, feeding back the measurements, and administering medicine suitable for a lung condition in a single use. The inhaler 1 of the present invention includes a lung function measuring unit 2 having a spirometer for measuring lung function, and, using a computing unit 5, compares the lung function measurements with a medication pattern table stored in a storage unit 7 and determines a disease severity and a diseased region of the lung. Based on the determination results, the computing unit further selects types and particle diameters of medicines suitable for the lung condition, and controls an ejection unit 3 including a plurality of ejection portions to eject the medicines required for treatment in a single use.

The invention discloses a chronic obstructive pulmonary disease testing system based on machine learning. The system comprises a lung function detector, a processor and a display unit; the lung function detector is used for obtaining function detection items of lungs of a person to be tested and measurement values of the items; the processor is connected with the lung function detector and comprises a main component feature analysis module, a decision tree construction module and a decision tree testing module; the display unit is connected with the processor and used for outputting results of the processor; the chronic obstructive pulmonary disease testing system based on the machine learning is based on a machine learning model based on a decision tree, a relationship between a chronic obstructive pulmonary disease and all physical signs of lungs of a patient is established, and the system has the advantages of being high in testing accuracy, strong in reliability and more stable.

Non invasive measurement of infant lung function during unsedated sleep is achieved by a plethysmograph which comprises of a rigid acrylic box (10) with integral water sealed spirometer (11) and a vacuum-actuated neck seal (20) allowing "head out" monitoring. The neck seal comprises particulate material entrapped in the space between two layers of rubber, which become rigid when a vacuum is applied to the space. Tidal volume, respiratory rate and changes in functional residual capacity (FRC) are able to be recorded during unsedated REM and NREM sleep whilst monitoring with conventional polysomnographic methods. The head out configuration allows additional instrumentation to be used, avoids facial stimulation and allows unimpeded access to the upper airway.

An anti-inflammation substrate for decreasing the proinflammation induced by the cytokines and inhibiting the lung function degeneration is provided. The anti-inflammation substrate includes one selected from the group consisting of a 7-[2-[4-(2-chlorobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine, a 7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine, a respective pharmaceutical acceptable salt thereof, and a combination thereof.

The invention discloses a lung function meter which comprises an air pressure detecting end and a handheld terminal. The air pressure detecting end is provided with a controller, an air pressure sensor connected with the controller, a power supply module and a communication module. The handheld terminal is provided with a controller, a displayer connected with the controller and a communication module. The air pressure detecting end and the handheld terminal are connected in a wireless-communication mode. The invention further discloses a lung function detecting method which comprises the following steps that (1) the air pressure detecting end detects breathing air pressure in real time through the air pressure sensor; and (2) the handheld terminal displays the breathing air pressure collected by the air pressure detecting end in real time. The invention further discloses a mask with a lung function detecting function and a respiratory training device. The breathing air pressure of a user can be measured conveniently in an electronic mode, real-time displaying is achieved, and training control is carried out.

The invention discloses an Angelica keiskei wine brewing method. The Angelica keiskei wine brewing method comprises the following steps: 1, cleaning fresh grapes, draining, and beating to form a grape pulp; 2, filling the grape pulp into a container, and fermenting; 3, adding an Angelica keiskei material and white sugar after the fermentation is carried out for 2-3d, uniformly stirring to form a mixed pulp, and continuously fermenting for 30-40d to obtain an Angelica keiskei wine pulp; 4, filtering the Angelica keiskei wine pulp, and precipitating to obtain an Angelica keiskei wine; and 5, sealing the obtained Angelica keiskei wine for sale. The Angelica keiskei wine brewed through using the brewing method fully utilizes the nutrition of the Angelica keiskei and the grapes, contains abundant amino acids, has the efficacies of lung function improving, blood circulation reinforcing, blood pressure reducing, blood fat reducing, immunity improving, ageing preventing, digestion helping, fat reducing, appetite increasing, beauty treating, face caring and the like, and has the characteristics of simple method and less investment.

Methods and systems for assessing lung function using volumetric images obtained at inspiration and expiration. The method may include processing the first and second set of images to identify known anatomical structures of the lungs, registering the first set of images to the second set of images to match voxels of the first set of images to voxels of the second set of images as matched pairs of inspiratory and expiratory voxels, calculating a continuous probability of a lung characteristic at a location of the matched pairs of voxels, and displaying the result on a display. The method may also include classifying lung tissue at each location as normal, having air trapping without emphysema, or being emphysematous.

The described invention provides compositions and methods for treating a susceptible subject at risk of pulmonary complications of an acute lung injury caused by a severe infection with a respiratory virus and for restoring lung function to donor lungs. The methods include administering a therapeutic amount of a pharmaceutical composition comprising extracellular vesicles (EVs) comprising one or more miRNAs and a pharmaceutically acceptable carrier. The population of EVs can be derived from a patient who has recovered from an infection with the respiratory virus or has been exposed to anti-viral antibodies through treatment, can be derived from MSCs of a normal healthy individual, can be modified by a viral vector, or can be synthetic.