The invention discloses a pharmaceutical composition for treating rheumatism and rheumatoid disease, wherein the constituents include black-tail snake, gastrodia tuber, Clematis chinensis, pubescent angelica root, notopterygium root, ledebouriella root, speranskia herb, Loranthus mulberry mistletoe, cortex acanthopanacis, root of herbaceous peony, earthworm, achyranthes and cyathula root, dipsacus root, drynaria, east Asian tree fern rhizome, broomrape, psoralea fruit, eucommia bark, deer horn gum, homalomena rhizoma, hairy birthwort, batryticated silkworm, dragon's blood resin, Moghania philippinensis, futokadsura stem, rhizoma dioscoreae hypoglaueae, herba siehesbeckiae, root of red rooted saliva, buck grass, orienavine, anisetree bark, Japanese yam, pawpaw, large-leaf gentian root, and Tripterygium wilfordii 120-150, prepared Sichuan aconite root, prepared wild aconite root, processed semen strychni each 280-320g, Chinese angelica root, red ginseng, astragalus root each 140-180, pipe-fish, wood louse, buthus martensi karsch, Chinese ephedra, licorice root each 70-80, safflower, Ligusticum wallichii, notoginseng, cassia twig, hornet nest 100-120, centipede 50-60, asaryl, aniseed 80-100 and Aconitum pendulum Busch 15-20.