3494 results about "Curative effect" patented technology

The invention discloses a knowledge graph construction method and system based on traditional Chinese medicine classics, and relates to the technical field of knowledge graph construction, and the method comprises the steps: collecting multi-source heterogeneous data of traditional Chinese medicine classics, carrying out the standardization processing, and generating a cross-time aligned standardized corpus through optical character recognition and multi-modal feature extraction; based on a language model and a causal reasoning engine, extracting an entity relationship and a dialectical rule from the standardized corpus, and generating a dynamic dialectical reasoning model supporting nonlinear reasoning; obtaining an output result of the dynamic dialectical reasoning model, and constructing a redundancy-removed and dynamically-calibrated traditional Chinese medicine knowledge base through knowledge fusion and conflict resolution of various traditional Chinese medicine classics; based on edge calculation and privacy protection technologies, real-time iteration and clinical curative effect feedback optimization of the knowledge graph are realized. According to the method, the problems of trans-era evolution, regional expression difference, multi-modal feature splitting and the like in the traditional Chinese medicine classics digitalization process are solved.

The invention provides a traditional Chinese medicine diagnosis and treatment decision method and system based on evidence, and relates to the technical field of diagnosis and treatment decision, and the method comprises the steps: obtaining patient information, screening evidence, classifying syndromes, generating a personalized treatment scheme, collecting feedback and monitoring reactions, quantifying the curative effect, and dynamically adjusting the scheme. The method is systematized and scientific, and has a good application prospect and popularization value. Through a feedback mechanism and multi-round iterative learning, the diagnosis and treatment scheme is continuously optimized, and it is ensured that the diagnosis and treatment scheme adapts to the change requirements of patients; and by utilizing statistical analysis, the interpretability of the model is enhanced, a doctor is helped to understand a decision process, and clinical confidence is improved.

The invention relates to the technical field of traditional Chinese medicine acupuncture and moxibustion and big data processing, in particular to a massive human tissue structure big data accurate identification method and system for traditional Chinese medicine acupuncture and moxibustion, and the system comprises a data fusion module, a knowledge graph module, a baseline model construction module, an effect prediction module, a remote monitoring module and a curative effect evaluation module. Compared with the prior art, a closed loop of'precise modeling-real-time feedback-intelligent optimization-safe evidence storage 'is formed through deep fusion of data driving and an intelligent algorithm, the acupuncture point positioning precision is improved by 30% or above, the risk early warning response time is shortened to be within 200 ms, the curative effect prediction accuracy rate reaches 85%, and the method has the advantages of being high in practicability and easy to popularize. Systematic technical support is provided for standardization and intellectualization of acupuncture treatment, and clinical safety and effectiveness are remarkably improved.

The invention provides a man-machine collaborative intelligent writing method and system for medical documents, and relates to the technical field of man-machine collaboration.The method comprises the steps that multi-modal clinical data of a patient is obtained for cross-modal semantic alignment, reasoning expansion is conducted based on a multi-level traditional Chinese medicine knowledge graph to generate a structured dialectical framework, and the structured dialectical framework is subjected to data processing; a logic consistency verification graph of a candidate medical record fragment set is constructed to solve semantic conflicts, and a medical record generation model is dynamically optimized in combination with clinical actual curative effect data, so that the intelligence degree, the standardization level and the clinical diagnosis and treatment value of traditional Chinese medicine medical record writing are improved.

The invention provides a large-model-driven traditional Chinese medicine curative effect multi-dimensional intelligent evaluation system and device, and relates to the technical field of traditional Chinese medicine curative effect intelligent evaluation. The system mainly comprises a data layer, a knowledge layer, a model layer and an application layer which are arranged in sequence; the data layer is used for collecting tongue images, pulse condition data, cardiovascular data, structured data, unstructured data and the like, and carrying out data treatment operations such as structured transformation, block chain evidence storage and abnormal value correction; the knowledge layer comprises a traditional Chinese medicine diagnosis and treatment knowledge map, a traditional Chinese medicine prescription compatibility relationship library, a curative effect evaluation standard library, a component-target network, a semantic mapping engine and a syndrome-treatment association map; the model layer comprises a multi-modal feature extraction module and a curative effect prediction module; the application layer comprises a doctor end and a patient end. According to the scheme, quantitative analysis of traditional Chinese medicine syndrome differentiation rules is realized through a large model, and the syndrome classification consistency of patients is improved.

The invention discloses a traditional Chinese medicine curative effect intelligent analysis and prediction platform, and relates to the technical field of traditional Chinese medicine analysis. The intelligent management platform is in communication connection with a data preprocessing and standardization module, a symptom description standardization processing module, a network relation analysis module, a network target positioning module, a network target navigation module, a drug effect prediction and evaluation module and a report generation and output module. According to the traditional Chinese medicine curative effect intelligent analysis and prediction platform, by integrating a machine learning technology, the accuracy of traditional Chinese medicine curative effect evaluation is remarkably improved, a large number of traditional Chinese medicine prescriptions, patient syndromes and curative effect data information are collected and analyzed, and the treatment effects of the traditional Chinese medicine prescriptions on different syndromes are evaluated by combining a network target and an established network relationship; and analysis results of the drug target intervention effect and the synergistic effect are provided, so that the action mechanism of the traditional Chinese medicine prescription can be deeply understood, and the traditional Chinese medicine prescription with a potential curative effect can be quickly screened out.

The invention relates to the technical field of acupuncture point recommendation, in particular to a clinical acupuncture assistance method and system based on a traditional Chinese medicine knowledge graph, and the method comprises the steps: obtaining a disease type corresponding to a to-be-detected patient; screening out each matching scheme of the target disease type and an acupoint connected with each target scheme from the target knowledge graph; the target knowledge graph acquisition method comprises the following steps: determining a curative effect matching degree and a practical matching degree between each historical disease type and each reference scheme; screening out a matching scheme of each historical disease type; and connecting each historical disease type with the matching scheme thereof, and connecting the acupoints in the matching acupoint combination corresponding to each historical disease type with the historical acupuncture scheme to which the acupoints belong, so as to form a target knowledge graph. According to the invention, the appropriate acupoint combination is adaptively recommended for the disease type corresponding to the to-be-detected patient, so that the traditional Chinese medicine can be assisted to carry out final acupoint selection, and the reasonability of acupuncture acupoint selection is improved.

The invention discloses an application of isorhamnetin-3-O-neohesperidin in preparation of a medicine for preventing and / or treating benign prostatic hyperplasia. In-vitro experiments show that the isorhamnetin-3-O-neohesperidin can inhibit proliferation of prostatic hyperplasia cells, promote apoptosis of the prostatic hyperplasia cells and regulate inflammatory response of the prostatic hyperplasia cells, and rat experiments show that the isorhamnetin-3-O-neohesperidin can improve the hormone endocrine disorder condition of an animal model body, and can inhibit the prostatic hyperplasia cells and promote the prostatic hyperplasia cell apoptosis and regulate the inflammatory response of the prostatic hyperplasia cells. The anti-inflammatory ability of an animal model is enhanced, and the traditional Chinese medicine composition has a relatively good treatment effect on prostatic hyperplasia caused by testosterone propionate. The medicine for preventing and / or treating benign prostatic hyperplasia, provided by the invention, contains a pharmacodynamic dose of isorhamnetin-3-O-neohesperidin and a pharmaceutically acceptable carrier or auxiliary material, can be prepared into a medicine dosage form which is convenient for clinical use and can play an optimal curative effect, and has a relatively high clinical application value.

The invention discloses a fungus extract capable of effectively regulating uric acid metabolism and relieving inflammation as well as a preparation method and application of the fungus extract, and belongs to the technical field of deep processing of edible fungi. Schizophyllumcommuneh and poplar phellinus sporocarp are mixed and extracted, and the prepared fungus extract can effectively inhibit activity of xanthine oxidase in serum and liver of mice, reduce content of uric acid, creatinine, urea nitrogen and the like in serum and promote excretion of uric acid, creatinine, urea nitrogen and the like in urine; meanwhile, the content of inflammatory markers such as IL-6 and TNF-alpha in mouse serum can be effectively reduced, inflammatory infiltration of liver and kidney cells is relieved, and the problem that an existing edible mushroom extract is not ideal in treatment effect on hyperuricemia is solved.

The invention belongs to the cross technical field of nanomedicine, tumor treatment and immunotherapy, and particularly provides tumor mitochondria-targeted copper death selective induction nanoparticles, which are prepared by the following preparation method: S1, specifically coupling TPY and MHI through condensation reaction to obtain MTPY; s2, MTPY and copper ions are subjected to complexation, and an MTPY-Cu complex is obtained; and S3, the MTPY-Cu complex and albumin are subjected to self-assembly, and the MTPY-Cu-coated Alb nanoparticles are formed. The dosage of copper is only 1 / 1000 of that of free Cu < 2 + >, and equivalent immune regulation and killing effects can be achieved; primary tumors and distant tumor focuses can be inhibited, and lung metastasis is reduced; immune memory can be induced, and relapse can be prevented; the traditional Chinese medicine composition is combined with cis-platinum to remarkably enhance the curative effect and reverse the induced immunosuppression; the invention has the advantages of high biological safety and no obvious liver and kidney toxicity or hemolytic reaction.

The invention discloses an application of a streptococcus salivarius subsp. Thermophilus Biohalo 23 tablet in preparation of a product for treating adenoid body inflammation. The preservation number of the streptococcus salivarius subsp. Thermophilus Biohalo 23 is DSM34540; the streptococcus salivarius subsp. Thermophilus Biohalo 23 tablet disclosed by the invention can be used for relieving the disease symptom of adenoid body inflammation and reducing the incidence rate of adenoid body inflammation, so that the streptococcus salivarius subsp. Thermophilus Biohalo 23 tablet disclosed by the invention has a remarkable curative effect on adenoid body inflammation, and particularly, through clinical tests, the streptococcus salivarius subsp. Thermophilus Biohalo 23 tablet has a remarkable curative effect on adenoid body inflammation. The streptococcus salivarius subsp. Thermophilus Biohalo 23 tablet disclosed by the invention can be used for remarkably improving symptoms such as tachypnea, mouth breathing, snoring, cough, nasal obstruction, hearing loss and the like, and also can be used for reducing the incidence rate of adenoid body inflammation, so that the streptococcus salivarius subsp. Thermophilus Biohalo 23 tablet disclosed by the invention can be used for treating the adenoid body inflammation.

The invention provides a preparation method of a recombinant collagen dressing, and belongs to the technical field of medical dressings. According to the technical scheme, stacked short sequences and continuous human collagen amino acid short sequences are repeatedly combined for multiple times to form recombinant collagen with specificity, and high similarity of the recombinant collagen with human collagen is ensured. On the basis, 4-FPBA is used as a cross-linking agent to respectively form a Schiff base bond responsive to pH and a boric acid ester bond responsive to glucose with CMCS and two kinds of HA with different molecular weights, and then the double-dynamic covalent cross-linked network adhesive hydrogel is synthesized. The triple-helix structure of the recombinant collagen is combined with a specific receptor on a cell membrane, and cell behaviors are regulated and controlled by inducing signal transduction through a cytoskeleton, so that skin microcirculation can be effectively improved, and a skin barrier can be repaired; the hydrogel dressing matrix has the effects of resisting inflammation, resisting oxidation, resisting bacteria, promoting healing and the like, the biological performance of the dressing is remarkably improved, and a better curative effect is achieved.

The invention discloses a quality control method of a traditional Chinese medicine preparation based on an IV-catfish orifice-freeing prescription, and relates to the technical field of analysis of traditional Chinese medicine preparations, and the quality control method comprises the following steps: carrying out microscopic identification on traditional Chinese medicine components in the IV-catfish orifice-freeing prescription, and determining a pharmacodynamic material basis. According to the quality control method for the traditional Chinese medicine preparation based on the IVV orifice-freeing prescription, various evaluation means such as a drug effect equivalent evaluation index, a stability test, a quality test and a clinical test are comprehensively applied, the consistency and reliability of the curative effect of the traditional Chinese medicine preparation can be remarkably improved, and the drug effect equivalent evaluation index is analyzed from the two factors of drug effect intensity and action time; the method ensures the equivalence of the medicinal component group and the original traditional Chinese medicine preparation, comprehensively detects the raw material medicines and the preparation, including characters, identification, inspection and content determination items, and ensures that the quality of each batch of samples meets the standard, so that the curative effect of the traditional Chinese medicine preparation is effectively guaranteed, and the efficacy of the traditional Chinese medicine preparation is improved.

The invention relates to the technical field of medical data processing, in particular to a knee osteoarthritis acupuncture curative effect prediction system based on deep learning. The system obtains acupuncture treatment parameters and acupuncture effect parameters of historical knee osteoarthritis patients; the historical knee osteoarthritis patients are divided into patient categories based on the acupuncture effect parameters, and the contribution degree is obtained according to the distribution of each acupuncture treatment parameter in each patient category and the distribution difference between the acupuncture treatment parameter and the acupuncture treatment parameter in other patient categories; acquiring a local curative effect feedback value according to the contribution degree and the acupuncture effect parameter, and further acquiring an evaluation score; and training the acupuncture curative effect prediction model through the acupuncture treatment parameters, the evaluation scores and the acupuncture effect parameters to obtain a trained acupuncture curative effect prediction model. According to the method, the evaluation score is dynamically obtained, the participation degree of each acupuncture treatment parameter of each historical knee osteoarthritis patient is accurately determined, and the accuracy of acupuncture treatment effect prediction model training is effectively improved.

The invention discloses a drug-combined anticancer composition and application of the composition in preparation of anticancer drugs. According to the present invention, the drug combination composition comprises the PARP inhibitor Olaparib and the calcium ion antagonist amlodipine maleate, the PARP inhibitor Olaparib and the calcium ion antagonist amlodipine maleate provide the synergistic effect, and compared with the single PARP inhibitor, the drug combination composition has characteristics of high stomach cancer sensitivity, significant gastric cancer efficiency improving, and wide application prospect. The Amlodipine in the drug combination composition provided by the invention enhances the curative effect of the PARP inhibitor Olaparib on the gastric cancer.

The invention relates to the technical field of medicine detection, and discloses medicine raw material detection equipment for improving the purity of raw materials, the medicine raw material detection equipment comprises a base and a supporting box, the bottom of the supporting box is fixedly connected to the outer side of the base, the top of the base is fixedly connected with a detection mechanism, and the top of the detection mechanism is fixedly connected with a detection plate; the top end of the supporting box is fixedly connected with a driving box, multiple filtering and impurity removing can be conducted on medicine raw materials through the impurity removing assembly, impurities in the raw materials can be screened out while the caked raw materials are screened out, the purity of the medicine raw materials is improved, the content of invalid or harmful ingredients in medicine can be reduced by removing the impurities, and therefore the medicine raw materials can be conveniently taken out. The purity and quality of the medicine are improved, the raw materials with higher purity can be used for preparing the medicine which is more efficient, safer and more stable, the treatment effect and the satisfaction degree of a patient are improved, and the content of active ingredients of the medicine can be improved by removing impurities, so that the curative effect of the medicine is enhanced.

The invention relates to the field of biological medicine, in particular to application of cepharanthine in preparation of a pathogenic bacterium biofilm scavenger, an anti-pathogenic bacterium medicine and a medical equipment coating material. Staphylococcus aureus is taken as a pathogenic bacterium, the removal effect of cepharanthine on a biological membrane is detected through biological membrane formation and destruction experiments, and the curative effect of cepharanthine on infection is evaluated by constructing a staphylococcus aureus infected mouse model. The result shows that the cepharanthine inhibits the formation of the staphylococcus aureus biological membrane and destroys the formed biological membrane; animal experiments show that the cepharanthine improves the survival rate of mice infected with the staphylococcus aureus, reduces the colonial colonization number of lungs of the infected mice, and improves the elimination capability of a host to pathogenic bacteria. Therefore, the invention has important significance in the aspects of research and development of targeted biological membranes and drugs for resisting drug-resistant bacterium infection, improvement of the curative effect of antibiotics, prolonging of the service life of the drugs and the like.

The invention discloses an external traditional Chinese medicine mixture aiming at genital skin mucosa ulceration wound repair and a preparation method thereof, relates to the field of traditional Chinese medicines, and aims to provide a genital skin mucosa ulceration wound repair medicine which has the effects of promoting wound repair and relieving itching, and is simple in component, small in allergy probability, light and thin in dosage form and good in skin feeling. The traditional Chinese medicine mixture is prepared from chicken butter, honeysuckle stem, felwort, cortex dictamni, fructus kochiae, radix scutellariae, cortex phellodendri, angelica sinensis, radix rehmanniae, radix arnebiae seu lithospermi, sanguisorba officinalis and bletilla striata. The traditional Chinese medicine mixture disclosed by the invention realizes simultaneous treatment of pruritus vulvae and ulceration, fills the treatment blank, relieves symptoms as soon as possible, shortens the treatment cycle and saves expenditure. The curative effect is prominent, and current clinical requirements are met. Cost and loss are reduced. Preparation is convenient, high-end machines are not needed, and preparation can be carried out at home.

The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a composite sleep-aiding composition based on agilawood and a preparation method thereof. The preparation method comprises the following steps: carrying out ultrasonic-assisted enzymolysis on agilawood by adopting amylase and cellulase, carrying out mixed fermentation on the agilawood subjected to enzymolysis by inoculating lactobacillus plantarum, lactobacillus johnsonii and saccharomyces cerevisiae, and carrying out sterilization, filtration, concentration and drying treatment on the fermented agilawood to obtain the agilawood fermentation product. According to the method, the release rate of active substances in the agilawood is increased, the composite sleep-aiding composition containing the agilawood fermentation product has a remarkable sleep-aiding effect, the preparation method is simple, the problem that an existing agilawood product is poor in sleep treatment effect is solved, and the agilawood fermentation product is safe, free of irritation and high in application value.

The invention discloses a maxillofacial surgery postoperative curative effect monitoring system, which relates to the technical field of medical diagnosis and comprises a data collection module, a transmission module, a data processing module, an interaction module and a recovery suggestion module, the data collection module comprises a face collection unit, an occlusion unit and a voice unit, the data collection module is used for being regularly worn by a postoperative patient, the face collection unit scans the maxillofacial surface of the patient, the occlusion unit is used for the patient to occlude and collect occlusion data, and the voice unit is used for collecting sound of the patient; uploading the collected data to a transmission module; and the transmission module uploads the acquired data to the interaction module based on the Internet of Things mode. According to the method, abnormal fluctuation or potential problems in the recovery process are found in time through data uploaded regularly, rehabilitation training plans and diet suggestions are customized for patients, or review time is adjusted for personalized treatment schemes, and the pertinence and effectiveness of treatment are improved.

The invention discloses a traditional Chinese medicine composition for treating acute exacerbation of chronic obstructive pulmonary disease, which is prepared from the following raw materials in parts by weight: 6-9 parts of honey-fried ephedra, 30-40 parts of gypsum, 6-9 parts of fried semen armeniacae amarae, 9-15 parts of fructus perillae, 9-15 parts of semen lepidii, 9-15 parts of radix asteris, 9-12 parts of radix peucedani, 9-12 parts of cynanchum glaucescens, 9-15 parts of thunberg fritillary bulb, 9-15 parts of honey-fried folium eriobotryae, 6-12 parts of rhodiola rosea and 6-9 parts of liquorice. Through scientific compatibility of the traditional Chinese medicine raw materials, clinical symptoms of patients in the acute exacerbation period of the chronic obstructive pulmonary disease can be effectively relieved, the acute exacerbation frequency and degree of the patients with the chronic obstructive pulmonary disease are reduced, and lung function decline is delayed. The traditional Chinese medicine composition is free of toxic and side effects and has the advantages of being good in curative effect, fast in effect taking, high in medicine effect, not prone to relapse and the like in the aspect of treating chronic obstructive pulmonary acute exacerbation.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a traditional Chinese medicine preparation for treating Parkinson's disease and a preparation method thereof. The traditional Chinese medicine preparation for treating Parkinson's disease comprises the following raw materials in parts by weight: 20-30 parts of bischofia polycarpa, 17-25 parts of eucommia ulmoides, 12-16 parts of artemisia sphaerocephala, 10-15 parts of lycopodium clavatum, 8-13 parts of elm leaves, 7-14 parts of pericarpium citri reticulatae, 5-10 parts of semen cuscutae and 2-7 parts of liquorice. In the formula, monarch, minister, assistant and guide are reasonably matched, the curative effect is exact, and the effects of regulating qi and blood, nourishing liver, warming kidney, activating blood and dissipating blood stasis are achieved. The compound can effectively improve core symptoms of Parkinson's disease and delay disease progression, is expected to be further developed into clinical drugs for treatment of Parkinson's disease, and provides an innovative scheme for traditional Chinese medicine treatment of neurodegenerative diseases.

The invention relates to application of cembratrienol in preparation of a medicine for preventing and / or treating psoriasis, and belongs to the technical field of biological medicine. The invention provides an application of cembratrienol in preparation of a medicine for preventing / or treating psoriasis. Researches find that cembratrienol can significantly inhibit secretion of inflammatory factors in a psoriasis-like cell model induced by M5; moreover, research finds that cembratrienol can significantly improve the skin lesion condition of an imiquimod-induced psoriasis mouse model, improve the weight loss degree of the psoriasis mouse model, relieve the pruritus condition of the psoriasis mouse model, improve the skin inflammation of the psoriasis mouse model, repair the skin barrier of the psoriasis mouse model, and improve the curative effect of the psoriasis mouse model. The body immune response of the psoriasis mouse model is reduced. Therefore, cembratrienol has a great application prospect in preparation of the medicine for preventing / treating psoriasis.

The invention relates to a traditional Chinese medicine composition for treating spleen-kidney qi deficiency and stasis toxin obstruction type diabetic nephropathy, which can effectively solve the medication problem for treating spleen-kidney qi deficiency and stasis toxin obstruction type diabetic nephropathy. The traditional Chinese medicine composition is prepared from, by weight, 37-33 g of astragalus membranaceus, 27-33 g of centella asiatica, 18-22 g of ligusticum wallichii, 18-22 g of winged euonymus twig, 18-22 g of salvia miltiorrhiza and 14-16 g of prepared rehmannia root. The traditional Chinese medicine composition is prepared by removing impurities from the raw materials, washing, airing, smashing and evenly mixing. The components are simple, scientific and reasonable, are compatible according to the main and secondary relationship of monarch, minister, assistant and guide, are mutually correlated and compatible in function to play a role, and are combined to play the roles of clearing heat and promoting diuresis, detoxifying and activating blood, reinforcing qi and nourishing yin, and tonifying kidney and replenishing essence, so that the traditional Chinese medicine is effectively used for preparing the medicine for treating spleen-kidney qi deficiency and blood stasis toxin blocking type diabetic nephropathy, and is good in curative effect and free of toxic and side effects. The traditional Chinese medicine composition is a great innovation of medicines for treating spleen and kidney qi deficiency and stasis toxin blocking collateral type diabetic nephropathy, and has remarkable social and economic benefits.

The invention discloses a lactobacillus plantarum strain from healthy people in a cold region and application of the lactobacillus plantarum strain. The lactobacillus plantarum strain is named as PL-H1, and is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC No.22286. The lactobacillus plantarum PL-H1 screened by the invention can obviously relieve the disease index, intestinal canal pathological change, inflammatory response and the like of an inflammatory bowel disease (IBD) model mouse. Moreover, compared with a standard strain WCSF1, the strain has the high metabolism characteristic of tryptophan and the function of adjusting the metabolism of IBD host intestinal tryptophan, and the curative effect of preventing and treating IBD is more remarkable. In addition, the lactobacillus plantarum strain PL-H1 can also improve the liver lipid accumulation and NAFLD activity of MCD fed mice, improve the blood lipid level and liver injury of the MCD fed mice and prevent liver fibrosis of the MCD fed mice, can be used for preventing and treating fungal infection related diseases, and is good in safety.

The invention relates to an antidepressant pharmaceutical composition and application thereof, and particularly discloses a pharmaceutical composition for treating depression as well as a preparation method and application thereof. The active pharmaceutical ingredients of the pharmaceutical composition are prepared from the following traditional Chinese medicines in parts by weight: 500 to 600 parts of radix bupleuri, 500 to 600 parts of fructus aurantii immaturus, 500 to 600 parts of radix aucklandiae, 500 to 600 parts of pericarpium citri reticulatae, 500 to 600 parts of rhizoma pinelliae preparata, 750 to 900 parts of herba taraxaci, 500 to 600 parts of scorched fructus crataegi, 300 to 360 parts of scorched semen arecae, 500 to 600 parts of paederia scandens, 300 to 400 parts of radix codonopsis, 300 to 400 parts of rhizoma corydalis and 500 to 600 parts of fried medicated leaven. The pharmaceutical composition has a remarkable curative effect on depression, animal experiments show that the pharmaceutical composition can remarkably enhance the social coefficient (showing that the pharmaceutical composition can improve social fear of depression patients) and improve sweet water preference (showing that the pharmaceutical composition is beneficial to transformation of negative emotions such as interest deficiency of the depression patients), and the pharmaceutical composition is safe to take, free of adverse reaction and toxic and side effects and free of toxic and side effects. And the composition can take effect quickly, and can take effect generally within 1-2 weeks after medication.

The invention discloses an AI syndrome differentiation and treatment model system suitable for a multi-dimensional difference environment, which comprises a data integration layer and a three-cause characteristic processing and dynamic dialectical model, and is characterized in that the data integration layer comprises outpatient service data, hospitalization data, follow-up visit data, physical characteristics, pathogenesis solar terms / five-transportation six-qi and regional medicinal material relationships; the three-factor feature processing comprises human-factor feature processing, time-factor feature processing and place-factor feature processing; the dynamic dialectical model comprises multi-modal data fusion, three-factor weight dynamic allocation and curative effect correction syndrome reasoning. The syndrome differentiation accuracy of chronic epigastric pain patients reaches 89.2%, the clinical curative effect and acceptability of a treatment scheme are improved, the average iteration period of the model is shortened to 72 h through a feedback closed-loop system, the method deeply conforms to Chinese geographical population characteristics, and the method has the advantages of being high in adaptability and good in application prospect through an environment perception-physique evaluation-dynamic syndrome differentiation three-level linkage mechanism. Precise diagnosis and treatment of one person with one prescription at once is achieved, and core technical support is provided for modernization of traditional Chinese medicine.

The invention belongs to the technical field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating cervical spondylosis and a preparation method thereof. The traditional Chinese medicine composition is prepared from the following bulk drugs by weight: 45 to 55 g of pinellia ternate, 45 to 55 g of bighead atractylodes rhizome, 45 to 55 g of gastrodia elata, 45 to 55 g of uncaria, 45 to 55 g of poria cocos, 95 to 105 g of tuber fleeceflower stem, 95 to 105 g of red sage root, 45 to 55 g of Chinese angelica, 45 to 55 g of ligusticum wallichii, 45 to 55 g of peach kernel, 45 to 55 g of safflower, 45 to 55 g of red peony root, 45 to 55 g of notopterygium root, 45 to 55 g of turmeric, 25 to 35 g of pseudo-ginseng, 25 to 35 g of leech, 95 to 105 g of root of kudzu vine, 95 to 105 g of ginkgo leaf, 95 to 105 g of clematis root, 45 to 55 g of earthworm, 45 to 55 g of drynaria rhizome, the traditional Chinese medicine is quick in effect and high in curative effect, and the clinical total effective rate of the traditional Chinese medicine is 100% according to clinical practice statistics.

The invention relates to the technical field of medical knowledge retrieval, in particular to a traditional Chinese medicine acupuncture field knowledge retrieval method and system based on deep learning, and the method comprises the following steps: obtaining an acupoint sequence and combining with semantics to construct a vector fragment, extracting symptom-related acupoint analysis response to generate a path sequence, and extracting a root combination vector matrix; according to the method, the sequence information of the acupuncture points in the meridian path is extracted, the semantic description and the major content are combined to construct the structured expression, the path organization and recognition capability is enhanced, the curative effect level and the treatment cycle are fused to form the sequence, the response pertinence of the acupuncture points is improved, and the method has the advantages of being simple in structure, convenient to operate and high in practicability. Through major treatment, direction and positioning root three-dimensional combination vectorization expression, semantic comparison and standardization are enhanced, keyword matching frequency and distribution density are combined, semantic association between input and knowledge is enhanced, and acupoint combinations are screened based on semantic matching and path continuity, so that the result is ensured to have relevance and practicability.

The invention provides a sarcandra glabra and honeysuckle compound preparation and a preparation method thereof, and during preparation, part of sarcandra glabra and honeysuckle are subjected to supercritical carbon dioxide extraction, volatile oil and medicine residues are collected, and the medicine residues and the rest of sarcandra glabra and honeysuckle are subjected to water extraction. A proper amount of beta-cyclodextrin is added into a water extract for inclusion, then concentration and supercritical extraction are performed to obtain volatile oil, and beta-cyclodextrin is used for inclusion, so that on the basis of increasing the efficacy of the volatile oil, the contents of chlorogenic acid and isofraxidin are increased, the curative effect of the medicine is enhanced, the synergistic effect of all components of the medicine is exerted, and the treatment effect of the medicine is improved. Menthol is clathrated with beta-cyclodextrin and then added into the paste powder to be mixed, granulated and tableted. On the premise of not influencing the dissolution of menthol and the direct stimulation effect on the throat, the effects of dispelling wind, clearing heat, relieving sore throat and relieving pain of the medicine are further enhanced, and meanwhile the problems that the quality of the product is not stable enough due to environmental change during storage, menthol is volatilized and is easy to crystallize, separate out and deteriorate are effectively solved.