38482 results about "Curative effect" patented technology

A neurological control system for modulating activity of any component or structure comprising the entirety or portion of the nervous system, or any structure interfaced thereto, generally referred to herein as a “nervous system component.” The neurological control system generates neural modulation signals delivered to a nervous system component through one or more neuromodulators to control neurological state and prevent neurological signs and symptoms. Such treatment parameters may be derived from a neural response to previously delivered neural modulation signals sensed by one or more sensors, each configured to sense a particular characteristic indicative of a neurological or psychiatric condition.

Devices, systems and methods by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, for example a baroreceptor in the carotid sinus. A control system may be used to modulate the baroreceptor activation device. The control system may utilize an algorithm defining a stimulus regimen which promotes long term efficacy and reduces power requirements/consumption.

The invention provides a method for predicting the efficacy of a compound for treating psoriasis based on a pharmacokinetic/pharmacodynamic model.

Nonlinear generalized dynamic regression analysis system and method of the present invention preferably uses all available data at all time points and their measured time relationship to each other to predict responses of a single output variable or multiple output variables simultaneously. The present invention, in one aspect, is a system and method for predicting whether an intervention administered to a patient changes the physiological, pharmacological, pathophysiological, or pathopsychological state of the patient with respect to a specific medical condition. The present invention uses the theory of martingales to derive the probabilistic properties for statistical evaluations. The approach uniquely models information in the following domains: (1) analysis of clinical trials and medical records including efficacy, safety, and diagnostic patterns in humans and animals, (2) analysis and prediction of medical treatment cost-effectiveness, (3) the analysis of financial data, (4) the prediction of protein structure, (5) analysis of time dependent physiological, psychological, and pharmacological data, and any other field where ensembles of sampled stochastic processes or their generalizations are accessible. A quantitative medical condition evaluation or medical score provides a statistical determination of the existence or onset of a medical condition.

This invention concerns the method of extracting salvianolic acid A from Chinese crude drug: danshen root, and the quality control methods and drug combinations, and the application of this drug. It can be used in the preparation of the prevention drugs for cardiovascular disease, liver damage, liver fibrosis, pulmonary fibrosis and other.

Methods of treating or suppressing mitochondrial diseases, such as Friedreich's ataxia (FRDA), Leber's Hereditary Optic Neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), or Kearns-Sayre Syndrome (KSS) are disclosed, as well as compounds useful in the methods of the invention, such as alpha-tocopherol quinone. Methods and compounds useful in treating other disorders are also disclosed. Energy biomarkers useful in assessing the metabolic state of a subject and the efficacy of treatment are also disclosed. Methods of modulating, normalizing, or enhancing energy biomarkers, as well as compounds useful for such methods, are also disclosed.

The invention relates to a Chinese medicinal preparation for treating bone fracture, which is prepared from 84 raw medicinal materials such as radix astragali, Chinese angelica, rehmanniae vaporata, rehmanniae praeparatum, suberect spatholobus stem, human placenta and the like. The medicament can be made into an oral preparation and external application preparation. A preparation method comprises the following steps: preparing an aqueous extract of the raw medicinal materials, and preparing an oral solution and a spraying agent from the aqueous extract; and preparing extracting pulvis from the aqueous extract, and preparing granules, pills, medicinal granules, tablets or capsules from the extracting pulvis. Raw medicinal powder also can be ground into raw powder pulvis which can be prepared into the granules, the pills, the medicinal granules, the tablets or the capsules, or the raw powder pulvis is prepared into external application ointment. In addition, the raw medicinal materials also can be infused to form medicinal liquor. The Chinese medicinal preparation has good curative effect on bone fracture diseases of different types, is mainly used for treating different types of fracture, muscles and bones breakage, traumatic injury, new and old incised wound and gunshot wound, bleeding and blood stasis which are caused by traumatism and other symptoms, and has the obvious curative effect on rheumatoid arthritis. The Chinese medicinal preparation is prepared from pure Chinese medicaments, and has convenient use, safety, reliability, no toxic or side effect and long-term use.

Milling and drilling tools and soft tissue management techniques are provided for arthroplasty that facilitate intraoperative and postoperative efficacy and ease of use. In one embodiment, resiliently biased soft tissue protective sleeves surround a side cutting tool and are interposed along the longitudinal axis of the cutting tool, preferably adjacent each side of the bone. The soft tissue protective sleeves are biased to track along the contour of the side of the bone and prevent the cutting tool from being exposed to soft tissue during the resection. In another embodiment, a pilot drill is initially utilized to create an initial bore in the bone to be resected. The pilot drill preferably has an end cutting arrangement and a non-cutting removal channel that minimizes the tendency of the pilot drill bit to drift off-axis as the initial bore in the bone is created. Once the initial bore is created, the pilot drill bit is withdrawn and a second side cutting tool, such as a milling bit, is then inserted into the bore to perform the desired surface resection.

The present invention generally relates to a combination of the fields of tissue engineering, drug discovery and drug development. It more specifically provides new methods and materials for testing the efficacy and safety of experimental drugs, defining the metabolic pathways of experimental drugs and characterizing the properties (e.g., side effects, new uses) of existing drugs. Preferably, evaluation is carried out in three-dimensional tissue-engineered systems, wherein drug toxicity, metabolism, interaction and/or efficacy can be determined.

The invention provides a curcumin oral emulsion and injection, wherein the emulsion comprises curcumin, oil, emulsifying agent and water, the injection also contains isotonic agent. The invention also discloses the process for preparing the emulsion and its use in preparing medicaments for treating or preventing tumor, resisting tumor transfer, enhancing curative effects of chemotherapy drugs, reducing side effects of chemotherapy and improving immunity functions for tumor patients.

The invention discloses a pharmaceutical composition for treating rheumatism and rheumatoid disease, wherein the constituents include black-tail snake, gastrodia tuber, Clematis chinensis, pubescent angelica root, notopterygium root, ledebouriella root, speranskia herb, Loranthus mulberry mistletoe, cortex acanthopanacis, root of herbaceous peony, earthworm, achyranthes and cyathula root, dipsacus root, drynaria, east Asian tree fern rhizome, broomrape, psoralea fruit, eucommia bark, deer horn gum, homalomena rhizoma, hairy birthwort, batryticated silkworm, dragon's blood resin, Moghania philippinensis, futokadsura stem, rhizoma dioscoreae hypoglaueae, herba siehesbeckiae, root of red rooted saliva, buck grass, orienavine, anisetree bark, Japanese yam, pawpaw, large-leaf gentian root, and Tripterygium wilfordii 120-150, prepared Sichuan aconite root, prepared wild aconite root, processed semen strychni each 280-320g, Chinese angelica root, red ginseng, astragalus root each 140-180, pipe-fish, wood louse, buthus martensi karsch, Chinese ephedra, licorice root each 70-80, safflower, Ligusticum wallichii, notoginseng, cassia twig, hornet nest 100-120, centipede 50-60, asaryl, aniseed 80-100 and Aconitum pendulum Busch 15-20.

The invention discloses a traditional Chinese medicine for treating acne through oral administration and is prepared by more than fifty traditional Chinese medicinal materials of gamene, broom cypress fruit, cortex dictamni, and so on; moreover, the invention is added with proper amount of pangolin so as to strengthen the effect of pus evacuation. According to the traditional Chinese theory of clearing away heat and toxic material, clearing lung heat, invigorating the spleen, relieving dyspepsia, promoting qi, removing dampness, dispelling wind, arresting itching, strengthening interior, relieving superficies, activating blood circulation, cooling the blood, removing stagnation, dredging the collaterals, resisting bacterium and diminishing inflammation, the invention makes use of the synergetic effect of the components to treat acne. The medicine for oral administration has short treatment course, stable curative effect and no recurrence; mild acne can be cured in about 30 days, moderate acne about 45 days and severe acne about 60 days; through the clinical observation of 100 cases of patients with acne, the effective rate of the invention can be 100 percent and the cure rate thereof can reach 62 percent; therefore the invention solves the problems of long treatment course, insignificant curative effect, easy recurrence and certain side effect on the human body in the existing medicines used for treating acne. .

The invention relates to a Chinese medicinal preparation for treating cancer, and the Chinese medicinal preparation is prepared from 110 raw material drugs, such as yew, barbed skullcap herb, hairyvein agrimony and laggera pterodonta. The preparation can be oral solution, granules, powder, capsules, electuary and tablets. 110 Chinese medicaments are adopted, and monarch, minister, assistant and guide drugs are reasonably compatible and are comprehensively taken to play the effect of treating both principal and secondary aspect of cancers. The raw material drugs adopted in the Chinese medicinal preparation are common Chinese medicaments, and are low in manufacture cost and small in side effect. The medicament has the advantages of capabilities of effectively strengthening the body immunity and attacking pathogen without hurting a body along with quick response, high curative rate, high heal rate, low relapse rate, treatment of both principal and secondary aspect of cancers, safety and reliability, and can be used for treating various types of cancers, especially lung cancer, gastric cancer, liver cancer, esophagus cancer, pancreatic cancer, cervical cancer and breast cancer.

The invention relates to chimeric antigen receptors (CAR), particularly relates to dual-signal independent chimeric antigen receptors (dsCAR), and also relates to immune response cells of the dual-signal independent chimeric antigen receptors (dsCAR) and uses of the immune response cells in preparation of drugs for treatment of malignant tumor and virus infected diseases. In detail, the dual-signal independent chimeric antigen receptors (dsCAR) can respectively identify two different family antigens of tumor cells and can respectively transmit two T-cell-activation related signals. One of the CAR can transmit a first T-cell-activation related signal by combing a ligand of a tumor specific antigen or a tumor-associated antigen to decide T-cell killing specificity, and the other CAR can transmit a second T-cell-activation related signal by combing a ligand of a membrane receptor (such as EGFR (epidermal growth factor receptor) family protein) widely expressed by the tumor cells to promote T cell activation, proliferation and survival. The dual-signal independent chimeric antigen receptors (dsCAR) can avoid the potential safety problems on the basis of maintaining curative effects of second generation and third generation CAR.

The invention discloses an anti-microbial healing-promoting hydrogel dressing and a preparation method therefor. The main ingredients of the dressing are water-soluble high-molecular polymers, functional polymers with pseudoplastic, anti-microbial agents and water. The above ingredients are dissolved into a whole after a series of technologies. The solution is poured into a mold, and the hydrogel dressing is obtained after curing and irradiation disinfection. The results of wound healing experiments and in vitro anti-microbial experiments show that the hydrogel dressing can promote wound healing effectively, and has good bacteriostatic activity to multiple bacteria (the sterilizing rate is above 70%). The anti-microbial healing-promoting hydrogel dressing is better than existing hydrogel dressings obviously, and has advantages of substantial anti-microbial curative effects, transparency, high water content, simple preparation method, pure product, nontoxicity, innocuousness, no stimulation, good biocompatibility and the like. The hydrogel dressing is suitable for large-area promotion and application.

The invention relates to a Chinese medicinal preparation for treating a prostate disease, which is a medicament prepared from 70 raw material medicaments such as ginseng, deerhorn glue, medicinal indianmulberry root, common curculigo rhizome and the like. The medicament can be prepared into oral liquid, granules, powder, capsules, electuary, tablets or pills. A preparation method of the medicament comprises the following steps of: (1) preparing water extracting solution by the raw material medicaments; (2) preparing oral liquid by the water extracting solution; (3) drying, crushing and sieving the water extracting solution, and taking screening as medicinal extracting powder; and (4) preparing tablets, granules, pills or capsules from the medicinal extracting powder. The preparation method also can comprise the following steps of: (1) crushing and sieving the raw material medicaments, and taking the screening as medicinal powder; (2) disinfecting and sterilizing the medicinal powder to obtain raw powder; and (3) preparing tablets, granules, pills, electuary or capsules from raw powder. The adopted raw material medicaments are common Chinese medicaments, so the Chinese medicinal preparation has the advantages of low manufacturing cost, and nearly no toxic or side effects. The medicament has good curative effects on prostatitis, prostatic hypertrophy and prostatomegaly, and has obvious effect on prostate cancers.

The invention discloses a special physiological regulator for maternal animals, and a preparation method thereof, and belongs to the field of feed additive. A technical scheme of the physiological regulator comprises: carrying out crushing and screening for dandelion, leonurus, licorice root and angelica; adding soybean meal and/or wheat bran; adding water to carry out immersing; adjusting pH value of the resulting mixture; carrying out a sterilization; inoculating probiotics to carry out a fermentation after cooling, followed by stoving after completing the fermentation to obtain the physiological regulator. With the prepared physiological regulator for the maternal animals, immunity and disease resistance of the maternal animals are raised, incidence rate of genital system infection is effectively reduced, feed inversion rate is increased, mammogenesis is improved, milk yield is raised, incidence rate of mammitis is reduced, and milk quality is improved. The physiological regulator has characteristics of quick onset, stable and reliable effect, no toxic and side-effect, no pollution, no residue, and no drug resistance generating, and meets requirements of safe feed additive and assurance of foods of animal origin. In addition, the physiological regulator for the maternal animals can be adopted as a veterinary drug through raising using dosage of the physiological regulator, and provides a substantial curative effect for prevention and cure of the mammitis.

The invention discloses an externally-used plaster which is prepared from more than 80 kinds of Chinese medicinal materials including frankincense, myrrh, mercurous chloride, dragon's blood resin, camphor, boneol, orpiment, sulfur, gamboge, lead monoxide, native copper, white alum, colophony, dragon's blood resin, musk, orpiment, lead monoxide, alkanna tinctoria, colophony, buck grass, wasp's nest, camphor, mercurous chloride, wood louse, and can be used for treating rheumatic arthritis and proliferative arthritis.

The invention relates to a Chinese medicinal preparation for treating the diabetes, which is prepared from 47 raw material medicaments in part by weight: astragalus, siberian solomonseal rhizome, common yam rhizome, cornus fruit and the like. A preparation method 1 for the Chinese medicinal preparation comprises the following steps: (1) preparing aqueous extract of the raw material medicaments; (2) preparing oral liquid from the aqueous extract; (3) drying and crashing the aqueous extract obtained by the step (1), and passing the powders through a screen to prepare medicament extract powders; and (4) preparing tablets, granules, pills, soluble granules or capsules with the medicament extraction powders. A preparation method 2 for the Chinese medicinal preparation comprises the following steps: (1) drying fresh pig pancreas and grinding the fresh pig pancreas into powders; (2) crushing other raw material medicaments, passing the powder through a screen to prepare medicament powders; (3) uniformly mixing the pig pancreas powders and the medicament powders, disinfecting and sterilizing to obtain raw powders; and (4) preparing oral tablets, granules, pills, soluble granules or capsules with the raw powders. Based on the principle of monarch, subject, assistant and envoy, the medicament of the invention has synergistic effect, addresses both the symptoms and root causes, has better curative effect on the diabetes, and has obvious effect of treating serious diabetes. The raw medicinal materials adopted by the Chinese medicinal preparation are common Chinese medicaments, have low production cost and have no toxic or side effects basically.

A medical diagnosis system based on big data comprises a diagnosis and treatment scheme database.Information of the diagnosis and treatment scheme database and information of a patient inspection result are combined and transmitted to a prescription generation module.The prescription generation module transmits the information to a patient drug-use module.The patient drug-use module transmits the information to an information feedback module.The information feedback module transmits the information to the diagnosis and treatment scheme database.The patient inspection result can also be transmitted to a patient information base.The diagnosis and treatment scheme database and the patient information base transmit the information to a hospital information system.The big data technology is utilized for building the diagnosis and treatment scheme data, the prescription generation module can synthesize all inspection result data and automatically give out prescription or treatment schemes, drug effect conflicts or drug-use contraindication among drugs can be avoided, curative effect feedback information of a patient is included, communications between a doctor and the patient can be increased, more treatment reference information can be given to the doctor, the patient can go to the doctor conveniently, and medical accidents can be reduced.

Systems and compositions comprising zotarolimus that are safer, more effective and produce less inflammation than rapamycin and paclitaxel systems are disclosed. Medical devices comprising supporting structures capable of containing or supporting a pharmaceutically acceptable carrier or excipient, which carrier or excipient can contain one or more therapeutic agents or substances, with the carrier including a coating on the surface thereof, and the coating having the therapeutic compounds, including, for example, drugs. Supporting structures for the medical devices that are suitable for use in this invention include coronary stents, peripheral stents, catheters, arterio-venous grafts, by-pass grafts, and drug delivery balloons used in the vasculature. These compositions and systems can be used in combination with other drugs, including anti-proliferative agents, anti-platelet agents, anti-inflammatory agents, anti-thrombotic agents, cytotoxic drugs, agents that inhibit cytokine or chemokine binding, cell de-differentiation inhibitors, anti-lipaedemic agents, matrix metalloproteinase inhibitors, cytostatic drugs, or combinations of these and other drugs.

The invention relates to a Chinese medical compound for curing cardiovascular disease, and is prepared by the following raw medicines: green tangerine peel, bupleurum, nutgrass galingale rhizome, turmeric root-tuber, pittosporm root, gentiana scabra bge, black nightshade herb, gambir plant, tuber fleeceflower root broil, radix astragali, cassia twig, ageratum, plantain seed, south dodder seed, red paeony root, szechuan lovage rhizome, kudzuvine root, malaytea scurfpea fruit, danshen root, hawthorn, safflower, pericarpium trichosanthis, blackberrykiky rhizome, tree peony bark, india madder root, dangshen, sojutsu var broil, indian buead, chicken's gizzard-membrane, combined spicebush root, cinnamon, baical skullcap root, ephedra herb, chinese magnoliavine fruit, fragrant solomonseal rhizome, radix stemonae broil, pinellia tuber broil, white mustard seed, nodakenin, sandalwood, rosewood heart wood, longstamen onion bulb, angelica, clematis root, kadsura pepper stem, ovientvine, herb pyrolae, desertliving cistanche, hairy antler, medicinal indianmulberry root, barbary wolfberry fruit, glossy privet fruit, dogwood, rhizoma anemarrhenae, amur corktree bark, spina date seed, platycladi seed, pubescent holly root, thinleaf milkwort root-bark broil, grassleaf sweelflag rhizome, silktree albizzia bark, twotooth achyranthes root, paris polyphylla, chinese date, oriental waterplantain rhizome, songaria cynomorium herb, papermulberry fruit, leech, cortex lycii radicis, earthworm, lucid ganoderma, glabrous greenbrier rhizome, magnetic stone dust, and longhairy antenoron herb with smallleaves. The invention has good curing effects on the applicable diseases.

A preparation method for porous microspheres of a biodegradable polymer is provided. The method comprises the following steps: (a) dissolving a biodegradable polymer in an organic solvent to form an oil phase of 1-30% (g/ml) concentration; (b) selecting a pore-forming agent 1-50% of the biodegradable polymer in the step (a) and dissolving the pore-forming agent in water to form an internal water phase; (c) adding dropwise the internal water phase into the oil phase at a volume ratio of (1-30):100, and stirring to form a primary emulsion; (d) preparing a polyvinyl alcohol aqueous solution of 0.5-10% (g/ml) concentration, which serves as an external water phase; (e) pouring the primary emulsion into the external water phase at a volume ratio of (3-30):100, stirring or performing ultrasonic treatment to form a double-emulsion, and allowing the polymer in the double-emulsion to solidify, thereby forming microspheres; (f) freeze-drying the microspheres to obtain the final product. The obtained porous microspheres of the biodegradable polymer have high porosity, large specific surface area and good adsorption and encapsulation properties; and are used for the adsorption and encapsulation of unstable protein drugs, polypeptide drugs and growth factors and can retain pharmaceutical activity and effectiveness thereof.

The composition for treating hyperlipemia contains one or more nicotinic acids or the derivatives and one or more Tatin compound as 3-hydroxy-3-methyl glutaryl coenzyme inhibitor in the effective amount and the active component weight ratio of 5-100 as well as medicinal supplementary material. The present invention is used in preventing and treating hyperlipemia and has long acting period and high comprehensive treating effect.

The invention discloses a Chinese medicine composite for treating chronic gastritis and a preparation method thereof. The Chinese medicine composite mainly comprises the following active pharmaceutical ingredients: medicated leaven, fructus hordei germinatus, radish seed, pericarpium citri reticulatae, rhizoma cyperi, rhizoma dioscoreae, fructus aurantii immaturus, jobstears seed, lignum dalbergiae odoriferae, grassleaf sweetflag rhizome, cortex magnoliae officinalis, styrax, tuckahoe, fructus amomi, radix et rhizoma rhei, semen pruni, radix trichosanthis, rhizoma coptidis, honeysuckle flower, dandelion, radix scrophulariae, largehead atractylodes rhizome, radix paeoniae alba, medicated leaven, radix angelicae sinensis and rhizoma corydalis, and the like. The Chinese medicine composite can be prepared to be any common oral preparation according to the conventional Chinese medicine preparation method. The Chinese medicine composite can obviously improve gas pain in the gastric cavity, decreased food appetite, fullness after dinner, sour regurgitation, stuffiness in chest and abdomen, heartburn, feverish dysphoria, gastric upset, fatigue, dry pharynx, stomach ache due to too hungry and full, infantile atrophy and the like, which has definite clinical effect, obvious curative effect and fast desired effect. The Chinese medicine composite also has the advantages of low cost, basically no toxic side effect and the like.

The invention belongs to the technical field of the pharmaceutical chemistry, and concretely discloses benzimidazole derivatives, and a preparation method and a medicinal use thereof. The benzimidazole derivatives comprise ligustrazine and NO donor derivatives, and the benzimidazole derivatives can rapidly release ligustrazine or NO in vivo, so there is an effective synergistic effect between the benzimidazole derivatives and azilsartan, thereby the benzimidazole derivatives enhances the antihypertension effect, reduces untoward effects, has an ideal protection effect on the liver and kidney of a patient, and fills a gap in the prior art.

The invention relates to a curcumin-polysaccharide conjugate as well as a preparation method and application thereof. The preparation method comprises the following steps of: grafting amino acid at one terminal of a diamine compound to polysaccharide through amidation to obtain a polysaccharide macromolecule with a free terminal of amino acid; and introducing curcumin on the polysaccharide frame by a Schiff base reaction. The preparation method is characterized in that 1, the water solubility and in-vivo and in-vitro stability of the curcumin can be improved due to grafting modification on the curcumin, and the generated curcumin-polysaccharide conjugate can be used as a novel macromolecular medicament indepterminalently; 2, the curcumin-polysaccharide conjugate has a strong oral absorption promoting effect, is high in safety, and can achieve the effects of promoting medicament absorption, improving the curative effect, reducing the toxic and side effect of the conjugate and the like; and 3, the amphipathy of the polysaccharide molecule is improved by introducing the hydrophobic group curcumin, so that the curcumin-polysaccharide conjugate can be self-assembled into nano-micelle, and can be used as a vector of an insoluble medicament. The preparation method is simple, low in cost, and applicable to large-scale continuous production.

A dispersing oxiracetam tablet for preventing senile dementia and treating hypomnesia is prepared from oxiracetam, disintegrant,lubricant, flowing aid and adhesive through proportionally and sequentially mixing, granulating, baking and tabletting. Its advantage is high curative effect.

The invention aims to provide a traditional Chinese medicine for treating apoplectic hemiplegia and general paralysis. The traditional Chinese medicine comprises the raw materials of dozens of animal medicines and plant medicines such as gardenia, white atractylodes rhizome, radix bupleuri, green tangerine peel, tangerine peel, peach kernel, almond, mastic, myrrh, rhizoma sparganii, rhizoma zedoariae, spatholobus stem, radix notoginseng, calamus, radix salviae miltiorrhizae, rhubarb, turmeric, buffalo horn, muscardine silkworm, cornu antelopis, ox gadfly, white grub, jiashu, eupolyphaga, earthworm, leech, succinum, scorpio, centipede, draconis sanguis, pearl, borneol, realgar, cinnabar, long-noded pit viper, black-tail snake, long-noded pit viper, cicada slough and the like. The medicines are pulverized and prepared into medicinal granules, tablets, oral liquid, honeyed pills, water-bindered pills and capsules. The traditional Chinese medicine is quantitatively taken on time and can be used for promoting blood circulation, relieving the stasis of blood, expanding the blood vessels, improving the blood circulation of the brain, inducing the functional recovery of the brain, regulating the function of each system of a human body comprehensively and reinforcing the stress resistance and the tolerance of the human body, so that the curative effect is good, the total effective rate reaches 100%, and the cure rate reaches 100%. The invention is suitable for various patients suffering from the apoplectic hemiplegia and the general paralysis.

The invention relates to a composition with an anti-tumor effect and application thereof. The composition consists of ginseng secondary glycoside and fungal polysaccharide of which the weight ratio is 1:0.01-500, and the preferable weight ratio is 1:0.1-50. The invention also discloses a preparation method for the composition. The composition has the effect of improving immunity and anti-tumor effect, has the treatment effect which is obviously superior to that of singly used ginseng secondary glycoside or fungal polysaccharide, and is suitable for treating tumors.