13 results about "Curculigo" patented technology

The invention belongs to the technical field of pharmaceutical preparations, and particularly relates to application of a composition to preparation of a medicine for improving IVF-ET postoperative embryonic development. The composition for regulating menstruation and promoting pregnancy is prepared from dehaired pilose antler, roasted herba epimedii, rhizoma curculiginis, radix dipsaci, herba taxilli, semen cuscutae, fructus lycii, fructus rubi, rhizoma dioscoreae, lotus seeds (without cores), poria cocos, radix astragali, radix paeoniae alba, fried spina date seeds, uncaria rhynchophylla, radix salviae miltiorrhizae, radix paeoniae rubra and caulis spatholobi. Based on an in-vitro fertilization-embryo transplantation technology, the ovulation function and the ovum quality after the menstruation regulating and pregnancy promoting pill intervenes a female mouse, and the embryonic development condition, the farrowing rate and the fetal development state after the female mouse is transplanted into the body are evaluated; it is proved that the menstruation-regulating and pregnancy-promoting composition, especially the menstruation-regulating and pregnancy-promoting pill, can improve the in-vivo development degree, in-vivo development quality and pregnancy outcome of an embryo after an in vitro fertilization-embryo transplantation (IVF-ET) operation.

The present invention discloses a curculigo orcinol synthase gene CoORS1 and application thereof in preparing orcinol. The nucleotide sequence of the curculigo orcinol synthase gene CoORS1 is shown in SEQ ID NO: 1. Acetyl-CoA and malonyl-CoA are used as raw materials. Under the catalysis of the curculigo orcinol synthase gene CoORS1, orcinol is produced. This is of great significance for the research on the biosynthesis regulation of curculigo orcinol glucoside.

The invention belongs to the field of veterinary drugs, and particularly relates to a traditional Chinese medicine composition for preventing African swine fever attenuated virus infection, a medicine prepared from the composition and a corresponding preparation method. The traditional Chinese medicine composition comprises the following components in parts by weight: 20-40 parts of rhizoma curculiginis, 5-15 parts of cynanchum thesioides, 5-15 parts of longspurred fairybells rhizome, 5-15 parts of triquetrous tadehagi root, 5-15 parts of apium graveolens, 10-20 parts of myricaria laxiflora and 10-20 parts of carex The traditional Chinese medicine composition is a pure traditional Chinese medicine preparation, is safe, free of toxic and side effects and palatability, has the characteristics of strengthening the body resistance to eliminate pathogenic factors, exact in curative effect, green, safe and capable of being mixed with feed / drinking water for use, can obviously reduce the morbidity of African swine fever and improve the health degree of swinery, and has good market application and popularization values.

The invention relates to the technical field of biological medicines, in particular to a lignan-reducing compound, an extraction method thereof and application of the lignan-reducing compound to a medicine for resisting postmenopausal osteoporosis (PMOP). The invention discloses a lignan-reducing compound, the structural formula of which is # imgabs0. The extraction method of the lignan-reducing compound mainly comprises the following steps: taking dry rhizome of curculigo macrophylla, performing reflux extraction twice with 95% ethanol at 60 DEG C, performing reflux extraction for 3 hours each time, combining extracting solutions, and performing reduced pressure distillation until no extracting solution residue exists, thereby obtaining the lignan-reducing compound. The curculigo macrophylla ethanol extract extractum is obtained. The invention provides a preparation method and an identification process of three novel lignan-reducing compounds for treating PMOP from curculigo macrophylla, which show that the three compounds have good effects of promoting bone formation and regulating bone metabolism.

The present application discloses a Chinese medicine composition, a Chinese medicine acupoint patch and a preparation method thereof, wherein the Chinese medicine composition is composed of the following raw materials in parts by weight: 10-30 parts by weight of Astragalus, 10-15 parts by weight of Citron, 5-10 parts by weight of Curcuma, 10-15 parts by weight of Curculigo, 5-10 parts by weight of Epimedium, 5-10 parts by weight of Clematidis, 5-10 parts by weight of Ephedra, and 3-10 parts by weight of Menthol. The above-mentioned Chinese medicine acupoint patch is used for both tonifying and purging, with Astragalus, Curculigo, and Epimedium replenishing, while Curcuma, Citron, Clematidis, and Ephedra dredging, taking into account strengthening the body and dispelling pathogenic factors, and Menthol harmonizing cold and heat, preventing dryness and protecting yin; through the reasonable compatibility of monarch, minister, assistant, and envoy, the combination of external treatment and internal adjustment is achieved, reflecting the flexible thinking of "internal and external treatment" of traditional Chinese medicine, and therefore having the effect of improving cancer-related fatigue in patients with lung cancer.

The invention belongs to the technical field of traditional Chinese medicine compositions, and particularly relates to a traditional Chinese medicine composition for treating perimenopausal syndrome as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared from 8-12 parts of rhizoma curculiginis, 8-12 parts of herba epimedii, 8-12 parts of radix morindae officinalis, 8-12 parts of radix angelicae sinensis, 4-6 parts of cortex phellodendri, 4-6 parts of rhizoma anemarrhenae, 8-12 parts of fructus ligustri lucidi, 8-12 parts of herba ecliptae, 13-17 parts of light wheat, 8-12 parts of radix glycyrrhizae, 8-12 parts of fructus ziziphi jujubae, 8-12 parts of fossil fragments and 8-12 parts of concha ostreae. The traditional Chinese medicine composition can improve the effect of treating the perimenopausal syndrome.

This invention discloses a traditional Chinese medicine composition for improving fever due to wind-cold and its application, belonging to the field of traditional Chinese medicine technology. Targeting the core pathogenesis of fever due to exogenous wind-cold, this invention combines modern thermoregulation and microcirculation pathological mechanisms, based on the principle of hypothalamic preoptic thermoregulatory center regulation. It abandons the drawbacks of Western medicine ibuprofen, which forcibly intervenes in the hypothalamic thermoregulatory center, constricts visceral blood vessels, and aggravates organ damage. It overcomes the technical defects of traditional Chinese medicine, which simply induces sweating to relieve exterior symptoms, depletes qi and damages yang, and easily leads to recurrence. The formula uses ephedra, curculigo, angelica pubescens, and galangal in combination. Through the synergistic effects of dispersing cold and clearing the lungs, warming yang and consolidating the collaterals, warming the middle jiao and dispelling pathogens, and unblocking the meridians, it gently regulates the homeostasis of the hypothalamic thermoregulatory center, expands spasmodic capillaries on the body surface and in the internal organs, improves the body's microcirculation, dispels cold pathogens from the skin surface, warms and unblocks the blood vessels of the internal organs, and also protects the heart, liver, and kidneys, strengthening the body's foundation and nourishing the vital energy. This achieves a comprehensive improvement of fever due to wind-cold, with mild medicinal properties, stable efficacy, and no risk of organ damage.

The invention discloses a traditional Chinese medicine composition for treating rheumatoid arthritis osteolysis and application thereof. The traditional Chinese medicine composition is prepared from the following medicinal materials in parts by weight: 6 to 12 parts of rhizoma curculiginis (roasted with wine), 9 to 15 parts of herba epimedii, 6 to 12 parts of radix clematidis, 10 to 15 parts of radix angelicae sinensis, 9 to 15 parts of radix achyranthis bidentatae, 6 to 15 parts of fructus lycii and 2 to 10 parts of liquorice root. The traditional Chinese medicine composition has the effects of synergistically warming and invigorating kidney yang and strengthening muscles and bones, can reduce expression of inflammatory factors TNF-alpha, IL-6 and IL-1beta in plasma of mice with collagen-induced arthritis (CIA), reduces inflammatory cell infiltration in synovial tissues, remarkably reduces the number of osteoclasts and erosion progress, and is good in safety.

The present invention belongs to the field of traditional Chinese medicine technology, and in particular relates to a traditional Chinese medicine composition for treating diffuse interstitial lung disease and its application. The traditional Chinese medicine composition of the present invention is made of the following raw materials in parts by weight: 10-12 parts of Curculigo, 10-20 parts of Epimedium, 30-45 parts of Astragalus, 20-30 parts of Ophiopogon, 15-30 parts of Clemati, 10-15 parts of Kadura Caulis, 10-15 parts of Trachelospermum officinale, 10-15 parts of Earthworm, 10-12 parts of Curcuma, 12-15 parts of Polygonum cuspidatum, 15-20 parts of Fritillaria thunbergii, and 6 parts of Licorice, which has better clinical treatment effect for diffuse interstitial lung disease. Further studies have shown that the above drugs have a synergistic effect after compatibility, and can inhibit alveolar epithelial cell-mesenchymal cell transformation and reduce excessive deposition of extracellular matrix by regulating the abnormal activation of TGF-β1 / Snail and Wnt3a / β-catenin signaling pathways, thereby treating IPF.

The present invention provides an artificial breeding method for a hybrid grouper of golden tiger. The artificial breeding method comprises the following steps: (1) selecting a healthy brown-spotted grouper aged 3 or above as the female parent; selecting a healthy blue-bodied large-spotted grouper aged 5 or above as the male parent; (2) cultivating the female parent by feeding feed I and feed II daily, wherein feed I is prepared from the following raw materials: soybean powder, vitamin E, scutellaria baicalensis leaf powder, dodder seed, amomum villosum, rehmannia root, and curculigo extract; (3) cultivating the male parent by feeding feed III and feed IV daily; wherein feed III is prepared from the following raw materials: fish meal, choline chloride, pine needle powder, salt algae powder, Morinda officinalis, and Tribulus terrestris extract; (4) after the parent fish reach sexual maturity, collecting eggs from the brown-spotted grouper and semen from the blue-bodied large-spotted grouper, performing artificial insemination, and obtaining fertilized eggs; (5) hatching the fertilized eggs to obtain fry. The breeding method of the present invention effectively increases egg production, and the fertilized eggs are of high quality and the yield of healthy seedlings is large.

The invention discloses a kidney-tonifying composition and a preparation method thereof. The kidney-tonifying composition is prepared from 8-12 g of rhizoma polygonati, 8-12 g of sea-buckthorn, 8-12 g of fructus lycii, 8-12 g of herba epimedii, 8-12 g of cynomorium songaricum, 3-6 g of rhizoma curculiginis and 8-10 g of semen allii tuberosi. The traditional Chinese medicine composition has the effects of tonifying kidney, replenishing essence and tonifying yin and yang through triple mechanisms of absorption promotion of sea-buckthorn, mild drug property of rhizoma polygonati and activation of herba epimedii.

A traditional Chinese medicine compound for treating blood stasis arthralgia type osteoarthritis belongs to the field of traditional Chinese medicine preparations and comprises 8 g of polygonum cuspidatum, 10 g of rhizoma sparganii, 10 g of turmeric, 10 g of motherwort, 10 g of artemisia anomala, 10 g of rhizoma curculiginis, 10 g of ramulus mori, 10 g of lycopodium clavatum, 10 g of bungarus parvus, 8 g of radix angelicae, 10 g of codonopsis pilosula, 10 g of semen coicis, 8 g of scutellaria baicalensis, 8 g of honeysuckle and 8 g of fructus forsythiae. All the medicines are put into a non-woven fabric bag to be sealed and put into a container, and water is added for boiling. Effective components of the traditional Chinese medicines are separated out by heating to prepare the fumigation and washing formula, and the effects of promoting blood circulation to remove blood stasis and activating meridians to stop pain are achieved when the fumigation and washing formula is used.

The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine composition for treating cerebellar ataxia syndrome, a preparation method, a pharmaceutical preparation and application. The composition comprises the following components: radix rehmanniae recen, prepared rehmannia root, cistanche, radix morindae officinalis, dogwood, dendrobe, rhizoma curculiginis, ginseng, radix ophiopogonis, polygala tenuifolia, rhizoma acori graminei, radix angelicae, poria cocos, schisandra chinensis, pericarpium citri reticulatae and fructus amomi. The preparation method comprises the following steps: soaking the radix rehmanniae recen and the prepared rehmannia root to obtain a mixture A; mixing other raw materials, and adding water for soaking to obtain a mixture B; and finally, combining the mixture A and the mixture B, and decocting to obtain the traditional Chinese medicine composition. The traditional Chinese medicine prescription can be used for treating the cerebellar ataxia syndrome and improving the main symptoms of ataxia, such as unstable walking, balance disorder and dysarthria; meanwhile, secondary symptoms such as urination and defecation disorder, sleep disorder and mental disorder can be improved, the compliance of a patient is improved, the progress of the disease course is delayed and stabilized, and the living quality of the patient is improved.