7 results about "Curculigo" patented technology

The present invention discloses a curculigo orcinol synthase gene CoORS1 and application thereof in preparing orcinol. The nucleotide sequence of the curculigo orcinol synthase gene CoORS1 is shown in SEQ ID NO: 1. Acetyl-CoA and malonyl-CoA are used as raw materials. Under the catalysis of the curculigo orcinol synthase gene CoORS1, orcinol is produced. This is of great significance for the research on the biosynthesis regulation of curculigo orcinol glucoside.

The present application discloses a Chinese medicine composition, a Chinese medicine acupoint patch and a preparation method thereof, wherein the Chinese medicine composition is composed of the following raw materials in parts by weight: 10-30 parts by weight of Astragalus, 10-15 parts by weight of Citron, 5-10 parts by weight of Curcuma, 10-15 parts by weight of Curculigo, 5-10 parts by weight of Epimedium, 5-10 parts by weight of Clematidis, 5-10 parts by weight of Ephedra, and 3-10 parts by weight of Menthol. The above-mentioned Chinese medicine acupoint patch is used for both tonifying and purging, with Astragalus, Curculigo, and Epimedium replenishing, while Curcuma, Citron, Clematidis, and Ephedra dredging, taking into account strengthening the body and dispelling pathogenic factors, and Menthol harmonizing cold and heat, preventing dryness and protecting yin; through the reasonable compatibility of monarch, minister, assistant, and envoy, the combination of external treatment and internal adjustment is achieved, reflecting the flexible thinking of "internal and external treatment" of traditional Chinese medicine, and therefore having the effect of improving cancer-related fatigue in patients with lung cancer.

This invention discloses a traditional Chinese medicine composition for improving fever due to wind-cold and its application, belonging to the field of traditional Chinese medicine technology. Targeting the core pathogenesis of fever due to exogenous wind-cold, this invention combines modern thermoregulation and microcirculation pathological mechanisms, based on the principle of hypothalamic preoptic thermoregulatory center regulation. It abandons the drawbacks of Western medicine ibuprofen, which forcibly intervenes in the hypothalamic thermoregulatory center, constricts visceral blood vessels, and aggravates organ damage. It overcomes the technical defects of traditional Chinese medicine, which simply induces sweating to relieve exterior symptoms, depletes qi and damages yang, and easily leads to recurrence. The formula uses ephedra, curculigo, angelica pubescens, and galangal in combination. Through the synergistic effects of dispersing cold and clearing the lungs, warming yang and consolidating the collaterals, warming the middle jiao and dispelling pathogens, and unblocking the meridians, it gently regulates the homeostasis of the hypothalamic thermoregulatory center, expands spasmodic capillaries on the body surface and in the internal organs, improves the body's microcirculation, dispels cold pathogens from the skin surface, warms and unblocks the blood vessels of the internal organs, and also protects the heart, liver, and kidneys, strengthening the body's foundation and nourishing the vital energy. This achieves a comprehensive improvement of fever due to wind-cold, with mild medicinal properties, stable efficacy, and no risk of organ damage.

The invention discloses a traditional Chinese medicine composition for treating rheumatoid arthritis osteolysis and application thereof. The traditional Chinese medicine composition is prepared from the following medicinal materials in parts by weight: 6 to 12 parts of rhizoma curculiginis (roasted with wine), 9 to 15 parts of herba epimedii, 6 to 12 parts of radix clematidis, 10 to 15 parts of radix angelicae sinensis, 9 to 15 parts of radix achyranthis bidentatae, 6 to 15 parts of fructus lycii and 2 to 10 parts of liquorice root. The traditional Chinese medicine composition has the effects of synergistically warming and invigorating kidney yang and strengthening muscles and bones, can reduce expression of inflammatory factors TNF-alpha, IL-6 and IL-1beta in plasma of mice with collagen-induced arthritis (CIA), reduces inflammatory cell infiltration in synovial tissues, remarkably reduces the number of osteoclasts and erosion progress, and is good in safety.

The present invention belongs to the field of traditional Chinese medicine technology, and in particular relates to a traditional Chinese medicine composition for treating diffuse interstitial lung disease and its application. The traditional Chinese medicine composition of the present invention is made of the following raw materials in parts by weight: 10-12 parts of Curculigo, 10-20 parts of Epimedium, 30-45 parts of Astragalus, 20-30 parts of Ophiopogon, 15-30 parts of Clemati, 10-15 parts of Kadura Caulis, 10-15 parts of Trachelospermum officinale, 10-15 parts of Earthworm, 10-12 parts of Curcuma, 12-15 parts of Polygonum cuspidatum, 15-20 parts of Fritillaria thunbergii, and 6 parts of Licorice, which has better clinical treatment effect for diffuse interstitial lung disease. Further studies have shown that the above drugs have a synergistic effect after compatibility, and can inhibit alveolar epithelial cell-mesenchymal cell transformation and reduce excessive deposition of extracellular matrix by regulating the abnormal activation of TGF-β1 / Snail and Wnt3a / β-catenin signaling pathways, thereby treating IPF.

The present invention provides an artificial breeding method for a hybrid grouper of golden tiger. The artificial breeding method comprises the following steps: (1) selecting a healthy brown-spotted grouper aged 3 or above as the female parent; selecting a healthy blue-bodied large-spotted grouper aged 5 or above as the male parent; (2) cultivating the female parent by feeding feed I and feed II daily, wherein feed I is prepared from the following raw materials: soybean powder, vitamin E, scutellaria baicalensis leaf powder, dodder seed, amomum villosum, rehmannia root, and curculigo extract; (3) cultivating the male parent by feeding feed III and feed IV daily; wherein feed III is prepared from the following raw materials: fish meal, choline chloride, pine needle powder, salt algae powder, Morinda officinalis, and Tribulus terrestris extract; (4) after the parent fish reach sexual maturity, collecting eggs from the brown-spotted grouper and semen from the blue-bodied large-spotted grouper, performing artificial insemination, and obtaining fertilized eggs; (5) hatching the fertilized eggs to obtain fry. The breeding method of the present invention effectively increases egg production, and the fertilized eggs are of high quality and the yield of healthy seedlings is large.

The invention discloses a kidney-tonifying composition and a preparation method thereof. The kidney-tonifying composition is prepared from 8-12 g of rhizoma polygonati, 8-12 g of sea-buckthorn, 8-12 g of fructus lycii, 8-12 g of herba epimedii, 8-12 g of cynomorium songaricum, 3-6 g of rhizoma curculiginis and 8-10 g of semen allii tuberosi. The traditional Chinese medicine composition has the effects of tonifying kidney, replenishing essence and tonifying yin and yang through triple mechanisms of absorption promotion of sea-buckthorn, mild drug property of rhizoma polygonati and activation of herba epimedii.