The invention relates to a plaster for treating rheumatism, arthralgia and myalgia. The plaster is prepared by screening, purifying, cleaning and drying Chinese medicaments such as safflower, unprocessed radix aconiti, unprocessed kusnezoff monkshood root, cyathula root, clubmoss herb, phryma, logwood, eucommia bark, drynaria rhizome, teasel, borax, nux vomica, antler, frankincense, clove, angelica dahurica, asarum, cinnamon, scorpion, centipede, jackinthepulpit tuber, unprocessed pinellia ternate, Szechuan lovage rhizome, atractylodes, unprocessed pangolin and ground beetle, adding the Chinese medicaments into a container in a weight ratio, adding sesame oil weighed in the weight ratio, and soaking for 7 to 10 days; and decocting over slow fire till the color is brown, removing residue, taking away the fire, slowly adding yellow lead, stirring till obtaining paste, sequentially adding myrrh, musk, resina draconis, camphor and borneol powder weighed in a ratio and stirring uniformly. The plaster for treating the rheumatism, the arthralgia and the myalgia is short in treatment course and quick in response, achieves the effects on the same day, can heal diseases in one week, is high in cure rate and avoids relapse.