49 results about "Smallpox" patented technology

A family protective shelter which can be erected quickly inside in a home living room, family room, patio, or on an outside lawn area. This dome tent enclosure is designed of clear plastic sheet material which is impervious to gases used to conduct chemical warfare (such as nerve gas, mustard gas, serin, cyanide, and the like) dispersed biohazard aerosol compounds (such as anthrax, smallpox, polio, bacteria, viruses, or fungi), or other atmospheric toxins, such as those from a nuclear fallout. This protective “pop-up”, external frame enclosure will be sized to house at least two adults comfortably (6×9×7 high inside, up to about 10×18′×7′ high), will incorporate a zip-lock entrance / egress isolation portal chamber, and will communicate to the outside world through combat gas mask filters, plus phone, computer and electrical outlet feed-through, and perhaps a water trap coupling. The invention can keep a family of 1 to 10 (with a larger size) relatively isolated and safe from the harmful effects of a chemical biohazard, or nuclear fallout enemy attack for a matter of hours up to several days. The portal chamber can also connect together additional modules.

The invention relates to a drug for treating severe cold and a preparation method thereof. The drug is prepared by 23 traditional Chinese medicines: Chinese ephedra, spica Schizonepetae, perilla leaf, radices puerarire, radix sileris, notopterygium root, angelica dahurica, rhizoma ligustici wallichii, bitter almond, balloon flower, liquorice, green rhizomes, dyers woad leaf, radix isatidis, forsythia, peppermint, burdock seeds, Baikal skullcap root, radix bupleuri, figwort, smallpox powder, Lophatherum gracile, pericarpium citri reticulatae, and the like. The drug can be taken conveniently and has obvious curative effect, thereby being a good drug for treating severe cold.

The invention concerns agents for the treatment of acute and chronic infections with human and animal pathogenic viruses which assemble along the cell membrane and are released through budding on the surface of the cell. Hereunto count especially causative agents of infectious diseases such as AIDS, hepatitis, hemorrhagic fever, SARS, smallpox, measles, polio or the flu. The subjects of the invention are agents that contain inhibitors of the protein folding as active components. Hereunto count inhibitors of cellular folding enzymes (the enzymatic chaperones) as well as substances that disturb the folding of proteins through chemical chaperones. The following substance classes and their derivates belong thereunto: Geldanamycin, Deoxyspergualin, 4-PBA or Herbimycin A. Due to these agents the highly organised processes of the assembly and the proteolytical maturation of virus structure proteins is disturbed. As a result the release and production of infectious decendent viruses is prevented.

The invention discloses a composition for skin regeneration. The composition comprises active components, and the active components include hyaluronic acid, oat beta-glucan, yeast lysis extract, biosaccharide gum-1, acetyl hexapeptide-8 and palmityl tripeptide-5; the active components of the composition also include glycerinum. Through combining multiple active components, the composition can effectively restore the skin damage and promote the skin wound healing; meanwhile, the composition also can restore skin crack, smallpox, stain, wrinkle, and scar.

The invention discloses a digestion-free protein product with placenta activity. The product is obtained as follows: fertilized eggs are hatched, a living embryo is used as a protein material (containing small live fish), and disinfection, shelling, crushing, blending, sterilization, ultra-long-time enzymolysis and separation for removal of insoluble matter are performed. The product is formed bycompound amino acid with dipeptide and tripeptide molecular weight between 300 DA and 500 DA and the average molecular weight being 125 DA. Science proves that only the part is digestion-free proteinand can be directly absorbed and utilized by the human body through small intestines. No digestion-free protein products are found on the market at present. The product has the benefits as follows: the digestion-free protein product is provided for old people and people with poor digestion functions, and protein balance can be kept. Three health revolutions including vaccination for smallpox, treatment of diseases caused by viruses and bacteria with penicillin and treatment with small-molecular active peptide exist in the human history. The root cause of all critical diseases is the cell faultproblem.

The invention discloses a medicament for curing gynaecological pruritus vulvae and coleitis. The medicament is prepared from lightyellow sophora root, cape jasmine fruit, coptidis rhizome, baical skullcap root, dandelion, dyers woad leaf, smallpox, common cnidium fruit, oriental wormwood, rheum officinale, amoorcorn tree bark and radix salviae miltiorrhizae. The preparation method comprises the following steps: firstly, grinding the crude drugs into powder, alcohol-extracting, concentrating and drying by baking to obtain the alcohol-extracted ointment powder, then, aqueous-extracting the residual marc, concentrating and drying to obtain the aqueous-extracted ointment powder, and mix the alcohol-extracted ointment powder and the aqueous-extracted ointment powder to obtain the finished extract. The preparation method has the advantages that the traditional Chinese medicine preparation can effectively cure gynaecological pruritus vulvae and various colpitis, the administration is safe, the curative effect is significant, and the preparation shows the same efficacy as various antibiotics.

The invention provides a traditional Chinese medical composition for treatment of sheep pox. The traditional Chinese medical composition consists of the following components by weight: 1-120 parts of honeysuckle, 1-120 parts of wild chrysanthemum, 1-120 parts of dandelion, 1-120 parts of herba violae, 1-115 parts of radix scutellariae, 1-115 parts of radix isatidis, 1-110 parts of cimicifugae foetidae, 1-115 parts of lithospermum, 1-110 parts of semiaquilegia root and 1-110 parts of liquorice. According to a method of Chinese veterinary dialectical treatment, the honeysuckle, the wild chrysanthemum, the dandelion, the herba violae, the radix scutellariae, the radix isatidis, the cimicifugae foetidae, the lithospermum, the semiaquilegia root and the liquorice are used together, a contagious disease caused by a sheep pox virus, namely sheep pox, can be treated effectively, typical smallpox on the body skin and sometimes the mucosa can be alleviated effectively, and the high mortality caused by fever of ill sheep can be reduced significantly.

An inactivated Polio Vaccine derived from Sabin strain for safe and effective immunization against Poliomyelitis is provided. A process of preparation for such vaccine and formulations thereof are also provided. Administration of the vaccine of the present invention along with other antigens provides immunization not only against polio infection but also against other pathogens causing Hepatitis C. Hepatitis D. Hepatitis E. Meningitis A. Meningitis B. Meningitis C. Meningitis W. Meningitis Y. Pnemococcal (23 valent or more). Smallpox, Typhoid, Bacille Calmette Guerin, Tuberculosis. Human Immunodeficiency Virus. Anthrax or the like, to which children or adults not immunized earlier are susceptible, particularly to which children are susceptible.

The use of glutathione to treat or prophylax smallpox infection, to treat or prophylax chemical warfare agents, or to treat or prophylax radiation injury to humans due to release of radioactive elements is proposed. The preferred formulation is an oral dosage form, with reduced glutathione stabilized by ascorbic acid in at least equimolar concentration. The formulation may be in unit dosage form or in bulk.

This invention describes compounds and pharmaceutical compositions useful as inhibitors of ubiquitination. The compounds and compositions of the invention are useful as inhibitors of the biochemical pathways of organisms in which ubiquitination is involved. In particular, the compounds and compositions are useful for treating diseases caused by viruses such as poxviruses and retroviruses. The invention further provides for methods of treating smallpox, Herpes virus and HIV infection in patients using the compounds and compositions of the invention.

The invention discloses traditional Chinese medicinal decoction for treating hemorrhoids, and belongs to the field of traditional Chinese medicines. The traditional Chinese medicinal decoction is prepared from the following herbal raw materials in weight: 25g of dandelion, 25g of red peony, 25g of moutan bark, 20g of rhizoma smilacis glabrae, 20g of radix angelicae, 20g of angelica sinensis, 20g of roasted oyster, 15g of raw rehmannia, 15g of radix sophorae flavescentis, 15g of dwarf lilyturf tuber, 15g of honeysuckle, 15g of chrysanthemum, 10g of smallpox powder, 10g of dendrobe, 10g of schisandra chinensis, 10g of peach kernel, 10g of scutellaria baicalensis, 10g of puffball, 10g of golden cypress, 10g of coptis chinensis, 6g of bupleurum, 6g of bitter orange and 5g of liquorice. The traditional Chinese medicinal decoction has the effects of clearing heat, promoting diuresis, cooling blood to remove stasis, tonifying Qi to promote blood circulation, removing swelling and stopping pains; medical difficulties that the hemorrhoids attacks repeatedly and cannot be cured after long-time treatment are completely overcome; and the traditional Chinese medicinal decoction can treat both symptoms and root causes and has no any toxic side effect.

A pharmaceutical composition including an adjuvant effective amount of a protected inosine monophosphate (IMP) compound. The pharmaceutical composition includes the protected IMP compound alone, or in combination with vaccine agents with or without additional adjuvants. The pharmaceutical composition can be utilized as a vaccine composition or can be included with existing vaccine compositions in order to increase a specific T lymphocyte mediated immune response thereto. Various methods relating to the pharmaceutical composition and N the vaccine are described herein. The vaccines can be employed to prevent or treat infections. Additionally, the pharmaceutical compositions not only increase T-cell responses, but also confer, by pretreatment, non-specific protection against a variety of pathogens. This combination of actions is appropriate for enhancing defense against bioterrorism with organisms like smallpox or anthrax.

The invention discloses live embryos obtained by incubating fertilized eggs, and the live embryos are protein raw material and soybean protein raw material. The living embryos and the soybean proteinare mixed, and are subjected to pulverizing, sterilization, enzymolysis for a very long time and separation to remove insoluble matters so as to obtain a double protein digestion-free protein productwith placenta activity. The product consists of composite amino acids, wherein the dipeptide tripeptide molecular weights are 300-500DA and the average molecular weight is 120DA. Science confirms thatonly the part is the digestion-free protein which can be directly absorbed and utilized by the human body directly through small intestines. No digestion-free protein product is found on the market today. The beneficial effects of the invention are that: the invention provides the digestion-free protein product for the elderly with reduced digestive function caused by aging so as to ensure protein balance. Human history has three times of health revolutions: the first time is vaccination for smallpox, the second time is treatment of diseases caused by viral bacteria with penicillin, and the third time is small molecule active peptide treatment. The root cause of all major diseases is the problem of cell failure.

Disclosed is a composition for the inhibition of transplant rejection and the prevention and treatment of skin diseases, comprising a cordyceps mycellia extract as an active ingredient. The cordyceps mycellia extract significantly suppresses the production of antibodies to transplants without side effects, such as weight change. Based on natural material, the composition is non-toxic and harmless to the human body and thus can be used as an immunosuppressant for organ transplantation. Also, it stops oozing from sores and is useful in the prevention and treatment of skin diseases, including atopy, allergic reactions, decubitus ulcers, pemphigus and smallpox.

The invention belongs to the field of health-care products and particularly relates to raw fish enzyme, a preparation method of the raw fish enzyme and anti-inflammation and pain relieving paste. The raw fish enzyme is prepared from the raw materials of fruits, sugar, water and raw fish slices. The fruits are fruits high in sugar content. Sugar includes brown sugar and glucose. The raw fish is saltwater fish. The raw fish enzyme have the advantages that the raw fish enzyme can diminish inflammation and relieve pains, has good curative effects on arthritis, shoulder periarthritis and sciatica and can treat seborrheic smallpox.

The invention relates to a preparation method for an acne-removing repairing mask containing licorice extract and belongs to the technical field of mask preparation. The preparation method provided by the invention comprises the following steps: preparing a mask base cloth, preparing the licorice extract, preparing an aqueous phase solution, preparing an oil phase solution, preparing essence and preparing the mask. The liquorice has the effect of clearing away heat and toxic materials and the antisepsis and anti-inflammation effects. The acne-removing repairing mask is especially suitable for the skin with smallpox pustules and being frequently inflamed and is capable of calming, eliminating face acne and effectively preventing the smallpox pustule acne from appearing. The procyanidine is a main functional component of grape pip, has an ultrahigh capacity for resisting against oxidation and removing free radical and is capable of fundamentally stopping the release of inflaming factor so as to eliminate the inflammation symptom, such as acne, and restrain the allergic phenomenon. The grape pip is capable of restraining the generation of enzyme required by histamine and preventing the histamine from generating so as to relieve the inflammation symptom and effectively remove acne. The fibroin has the effect of repairing the skin tissue cells. The mask provided by the invention is high in natural component content, is easily absorbed and has an excellent acne-removing effect. The preparation method is simple.

The invention provides traditional Chinese medicine mask powder and a traditional Chinese medicine mask prepared by the same. The traditional Chinese medicine mask powder is mixed powder prepared from, by weight, 10-40 parts of bletilla striata, 15-40 parts of bighead atractylodes rhizome, 10-50 parts of radix angelicae, 15-45 parts of white poria, 15-50 parts of rose, 15-50 parts of silkworm larva, 10-40 parts of scutellaria baicalensis, 20-45 parts of coptis chinensis, 10-60 parts of pigeon excrement, and 10-50 parts of mint. The traditional Chinese medicine mask powder has significant effects in whitening skin, smoothing fine wrinkles, preventing wrinkles, reducing smallpox and stain, nourishing and balancing skin, and others; besides, the mask powder takes effect quickly.

We have developed two new PCR based assays to detect Orthopoxvirus DNA which when tested under simulated clinical conditions, have proven to be very sensitive, rapid and robust. Importantly, we were able to construct artificial templates for use as positive controls in the RFLP analysis necessary to differentiate variola and monkeypox viruses from the Orthopoxvirus species that normally cause relatively insignificant disease in man. Our assays will provide a lab that has already undertaken the isolation of DNA from a patient sample in biocontainment, a sensitive and controlled assay for the detection and differentiation of human-tropic orthopox viruses.

The invention relates to a drug for treating severe cold and a preparation method thereof. The drug is prepared by 23 traditional Chinese medicines: Chinese ephedra, spica Schizonepetae, perilla leaf,radices puerarire, radix sileris, notopterygium root, angelica dahurica, rhizoma ligustici wallichii, bitter almond, balloon flower, liquorice, green rhizomes, dyers woad leaf, radix isatidis, forsythia, peppermint, burdock seeds, Baikal skullcap root, radix bupleuri, figwort, smallpox powder, Lophatherum gracile, pericarpium citri reticulatae, and the like. The drug can be taken conveniently andhas obvious curative effect, thereby being a good drug for treating severe cold.

The invention relates to a traditional Chinese medicine for treating otogenic brain abscess, and belongs to the technical field of the traditional Chinese medicine. The traditional Chinese medicine for treating the otogenic brain abscess is characterized in that raw material medicines comprise the following components: 6 to 20 parts of smallpox powder, 6 to 15 parts of thunberg fritillary bulb, 5 to 15 parts of phellodendron, 5 to 15 parts of angelica dahurica, 6 to 12 parts of honeysuckle, 3 to 10 parts of dried orange peel, 4 to 15 parts of Chinese radish seed, 3 to 9 parts of poria cocos, 5 to 15 parts of borneol, 3 to 10 parts of polygonatum, and 5 to 15 parts of rhizoma phragmitis. The traditional Chinese medicine preparation provided by the invention is safe, reliable and effective and has no toxic or side effects.

The present invention relates to a Chinese medicine virus-resisting preparation for curing various virus infections. It is made up by using an insect body cell capable of strongle phagocytizing various viruses as raw material through a scientific preparation process. Said Chinese medicine virus-resisting preparation has the functions of promoting eruption, removing toxic material, regulating immunity, promoting production of body fluid, strengthening normal function of the body and raising immunity, and can be used for curing various virus infected diseases of measles, smallpox, common cold, virus pneumonia and others.

The present disclosure relates to a method of treating at least one Cell-Associated Neurotoxicity Syndrome (ICANS), cancer-related cognitive impairment, Infusion Reaction Syndrome (IRS), Capillary Leak Syndrome (CLS), Tumor Lysis Syndrome (TLS), Macrophage Activation Syndrome (MAS), Systemic Inflammatory Response Syndrome (SIRS), Immune Reconstitution Inflammatory Syndrome (IRIS), Graft-Versus-Host Disease (GVHD), Acute Respiratory Distress Syndrome (ARDS), sepsis, Ebola, avian influenza, smallpox, Systemic Inflammatory Response Syndrome (SIRS), and Immune-related Adverse Events Syndrome (IrAES) in a subject in need thereof, comprising administering a mast cell stabilizer or a compound of Formula I or Formula II: Formula I, Formula II, wherein R1 is halogen, OH, or —OC(O)C1-5alkyl R2 and R3 are each independently selected from CO2R4 or CH2OR5; R4 is i L, Na, K, H, C1-5alkyl, or —CH2CO(C1-5alkyl); and R5 is H or C(O)(C1-5alkyl), or a pharmaceutically acceptable salt thereof.

A vaccine composition for combating Pox viridae viral infections in living organisms such as mammals (including humans) comprises TAP-1 and / or TAP-2 to augment the antigen processing capability of infected cells and hence their immunogenicity. The composition may be used alone or, preferably, as an immunogenicity-enhancing adjuvant with a pox antigen-based vaccine, especially in the treatment or prophylaxis of viral infections such as smallpox.

The invention provides a Chinese traditional medicament for treating leukoderma, which comprises liniment and matched powder preparation for oral administration. The principal raw materials include fresh wasp vegetable, smallpox leaves, polyrhachis vicina and flatstem milkvetch seed.