Patents
Literature
Patsnap Eureka AI that helps you search prior art, draft patents, and assess FTO risks, powered by patent and scientific literature data.

68 results about "Diuresis" patented technology

Diuresis (/ˌdaɪəˈriːsɪs/) is increased urination and the physiologic process that produces such an increase. It involves extra urine production in the kidneys as part of the body's homeostatic maintenance of fluid balance.

Traditional Chinese medicine composition for treating cervical spondylosis and preparation method and application thereof

The invention relates to a traditional Chinese medicine composition for treating cervical spondylosis and a preparation method and application thereof, and belongs to the field of traditional Chinese medicine. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 14.4 to 21.6 parts of radix astragali seu hedysari, 14.4 to 21.6 parts of radix paeoniae alba, 14.4 to 21.6 parts of caulis spatholobi, 14.4 to 21.6 parts of radix puerariae, 14.4 to 21.6 parts of ramulus mori, 7.2 to 10.8 parts of fructus lycii, 7.2 to 10.8 parts of rhizoma gastrodiae, 7.2 to 10.8 parts of rhizoma chuanxiong, 7.2 to 10.8 parts of radix clematidis, 7.2 to 10.8 parts of rhizoma alismatis, 7.2 to 10.8 parts of rhizoma atractylodis macrocephalae and 2.4 to 3.6 parts of radix notoginseng. The invention further provides a preparation method and application of the traditional Chinese medicine composition. Aiming at a compound syndrome type of liver and kidney deficiency combined with phlegm-damp collateral blocking cervical spondylosis, the rhizoma alismatis and bighead atractylodes rhizome pairs are introduced to achieve the effects of clearing damp, promoting diuresis, tonifying spleen and drying dampness together, and the traditional Chinese medicine is specially used for treating phlegm-damp dizziness and is matched with the rhizoma gastrodiae, so that the effects of reducing phlegm, stopping wind and stopping dizziness are remarkably enhanced. Meanwhile, ligusticum wallichii capable of promoting blood circulation and qi circulation is introduced to move upwards to relieve pain and forms synergistic compatibility with caulis spatholobi, herba clematidis and radix puerariae, and the traditional Chinese medicine composition is mild in medicine property, remarkable in curative effect, low in side effect risk and suitable for long-term nursing of cervical spondylosis.
Owner:CHENGDU BAITER PHARM CO LTD

Premix for improving joint health of pets and preparation method thereof

The invention belongs to the field of pet food processing, and relates to a premix for improving joint health of pets and a preparation method thereof. The premix is added with the following natural components: rhizoma polygonati, rhizoma drynariae, eucommia ulmoides, ligusticum wallichii, liquorice, turmeric, poria cocos and Chinese yam. The whole formula has the effects of tonifying liver and kidney to consolidate the root, promoting blood circulation to remove meridian obstruction to treat symptoms, tonifying spleen to remove dampness to assist transportation and transformation, tonifying spleen to prevent dampness stagnation, promoting diuresis to prevent positive qi injury, treating both symptoms and root causes, combining dredging and tonifying, and directly reaching the effects on joints. The premix can tonify cartilage, strengthen ligament, relieve pain, supplement synovial fluid, effectively improve the arthritis health of pets and improve the life quality of pets.
Owner:LUNAN PHARMA GROUP CORPORATION

Traditional Chinese medicine preparation for treating chronic prostatitis

The invention provides a traditional Chinese medicine preparation for treating chronic prostatitis, and relates to the technical field of traditional Chinese medicine pharmacy. The traditional Chinese medicine preparation is prepared from black nightshade, hypericum perforatum, yam rhizome, rhizoma sparganii, common sage herb, chingma abutilon seed, polyporus umbellatus, uniflower swisscentaury root, corydalis amabilis, aspongopus, glossy privet fruit, fructus broussonetiae, radix ophiopogonis, tuber fleeceflower stem, day lily and liquorice. The traditional Chinese medicine preparation has the effects of clearing heat and promoting diuresis, promoting blood circulation to remove blood stasis, nourishing yin and soothing nerves and tonifying liver and kidney. The traditional Chinese medicine preparation disclosed by the invention has a remarkable treatment effect on CNP rats, and the prostate pathological injury condition and inflammatory response of the CNP rats are effectively relieved. In addition, the traditional Chinese medicine composition has a good treatment effect on relieving pain, frequent micturition, urgent urination, dysuria and other clinical symptoms and inflammation conditions of patients, and has a high total treatment effective rate on chronic prostatitis. The traditional Chinese medicine preparation provides a new scheme for treating chronic prostate.
Owner:THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIV

Diarylamide compound and application thereof

A use of a diarylamide compound having the structure as shown in formula (I) or a pharmaceutically acceptable salt thereof in preparing a drug which acts as a urea transporter protein inhibitor, and a novel diarylamide compound. The diarylamide compound has urea transporter protein inhibitor effect, and can produce urea selective diuresis in the body without obvious toxicity.
Owner:SUNSHINE LAKE PHARMA CO LTD

Traditional Chinese medicine composition for treating urolithiasis and preparation method and application thereof

The invention relates to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition for treating urolithiasis and preparation and application thereof. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials and monomers in parts by weight: 10 to 30 parts of endothelium corneum gigeriae galli, 10 to 30 parts of rhizoma phragmitis, 10 to 30 parts of poria cocos, 10 to 20 parts of radix angelicae sinensis, 10 to 20 parts of herba cistanche, 10 to 20 parts of herba cepbalanoplosis segeti, 10 to 15 parts of fructus gardeniae, 5 to 10 parts of liquorice root and 1 to 6 parts of gossypotin 8-O-glucuronide. According to the traditional Chinese medicine theory of clearing heat, treating stranguria, dissolving stone and strengthening body resistance, modern pharmacological research is combined, scientific compatibility is carried out through chemical cutting, the synergistic effects of clearing heat, cooling blood, inducing diuresis, treating stranguria, dissolving stone, relieving pain, tonifying kidney and strengthening body resistance are achieved, the preparation process is efficient and controllable, and clinical application is safe and effective.
Owner:NANJING UNIV OF TRADITIONAL CHINESE MEDICINE

Medicinal composition for strengthening body resistance and nourishing liver as well as preparation method and application of medicinal composition

The invention discloses a medicinal composition for strengthening body resistance and nourishing liver as well as a preparation method and application thereof. The preparation method of the composition comprises the following steps: weighing the 15 medicinal materials according to the formula amount, crushing the turtle shell, decocting for about half an hour, then adding the rest medicinal materials, decocting, filtering, and concentrating the water decoction to 1 / 3-1 / 5 of the water addition amount, thereby obtaining the traditional Chinese medicine composition. The healthy-energy-strengthening and liver-nourishing soup has the effects of inducing diuresis, nourishing the liver, relieving ascites due to cirrhosis and the like, can relieve the symptoms of patients suffering from cirrhosis due to deficiency of healthy energy, blood stasis and qi stagnation and water retention, and can be used for treating cirrhosis diseases. The prepared decoction is fast in oral administration absorption and fast in drug effect exertion. And the product has high safety and no adverse reaction.
Owner:THE FIRST AFFILIATED HOSPITAL OF GUIZHOU UNIV OF TRADITIONAL CHINESE MEDICINE

A traditional Chinese medicine composition for treating chronic bronchitis combined with emphysema and its preparation method

ActiveCN118252895BAntipyreticAnalgesicsWolfiporia extensaObstructive chronic bronchitis
The present invention discloses a traditional Chinese medicine composition for treating chronic bronchitis combined with emphysema. The composition is prepared by extracting the following traditional Chinese medicine raw materials in parts by weight: 20-30 parts of ginseng, 15-25 parts of astragalus, 20-30 parts of prepared rehmannia, 18-22 parts of schisandra, 15-25 parts of pinellia, and 20-30 parts of poria. The composition nourishes the liver, spleen, and kidneys, reduces stomach qi, purges the lungs, and relieves asthma, promotes diuresis and reduces swelling, promotes blood circulation and removes blood stasis, regulates qi and resolves phlegm, and is suitable for treating chronic bronchitis combined with emphysema. The present invention also discloses a preparation method and use thereof.
Owner:TAIZHOU TRADITIONAL CHINESE MEDICINE HOSPITAL

Traditional Chinese medicine composition for treating uroschesis caused by benign prostatic hyperplasia as well as preparation method and application of traditional Chinese medicine composition

The invention discloses a traditional Chinese medicine composition for treating uroschesis caused by benign prostatic hyperplasia and a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition is prepared by mixing leeches, radix semiaquilegiae, cortex phellodendri, rhizoma anemarrhenae, Chinese lobelia, polygonum cuspidatum, herba patriniae, dianthus superbus, cowherb seeds, lumbricus, pericarpium citri reticulatae viride and lindera aggregata and then decocting with water. According to the traditional Chinese medicine composition, treatment is carried out synergistically from the three aspects of rapid relieving of emergency symptoms, targeted treatment of pathologic roots and synchronous recovery of whole body metabolic balance, and the four-in-one comprehensive curative effect of diuretic, anti-male, anti-inflammatory and tissue repair is achieved; the traditional Chinese medicine composition is simple in preparation method, low in cost and wide in safety window, is applied to treatment of uroschesis caused by benign prostatic hyperplasia, and provides a family-friendly traditional Chinese medicine solution capable of replacing or being combined with existing chemical medicines for patients.
Owner:NANJING UNIV OF TRADITIONAL CHINESE MEDICINE

A traditional Chinese medicine composition for preventing and treating feline urological disease, and a preparation method and application thereof

PendingCN122297620ADiseaseURINE BLOOD
This invention discloses a traditional Chinese medicine formula for preventing and treating feline urinary tract diseases, its preparation method, and its application. The formula consists of the following components in parts by weight: 15-25 parts of Psoralea corylifolia, 15-25 parts of Alpinia oxyphylla, 10-20 parts of Trigonella foenum-graecum, 5-15 parts of Zea mays, 5-15 parts of Juncus effusus, 10-20 parts of Dioscorea hypoglauca, 10-20 parts of Phellodendron chinense, 10-20 parts of Lonicera japonica, 5-15 parts of Paeonia lactiflora, and 5-15 parts of Glycyrrhiza uralensis. The traditional Chinese medicine formula provided by this invention has diuretic and urinary tract mucosal repairing effects. It can effectively relieve symptoms such as urinary stones, painful urination, hematuria, or gravel in the urine caused by damp-heat in the lower abdomen. It promotes the repair of the urinary tract mucosa in animals with urinary tract diseases, alleviates inflammatory responses, and prevents the formation of crystals in the urine.
Owner:SHANDONG HAICHUANG IND & TRADE CO LTD +1

Body fluid metering assembly, in particular for measuring diuresis

A body fluid metering assembly (1), in particular for measuring diuresis, is described, comprising: (i) a body fluid collection container (20) configured to collect a body fluid, such as urine; (ii) a body fluid metering unit (10) comprising a load cell (15) and a coupling mechanism configured to releasably couple the body fluid collection container (20) to the load cell (15), the body fluid metering unit (10) being configured to process sensor data supplied by the load cell (15) and derive a measure of the amount and / or flow rate of the body fluid accumulated in the body fluid collection container (20) as a function of the load applied on the load cell (15); and (iii) a tube (30) attached to an inlet port (20A) of the body fluid collection container (20) and configured to be connected to a source of the body fluid. The body fluid collection container (20) is a substantially rigid container and the coupling mechanism is a spring-loaded interlocking mechanism (50) configured to cooperate with one or more interlocking members (250a, 250b) provided on the body fluid collection container (20) and interlock with the body fluid collection container (20) to form a stable connection between the body fluid metering unit (10) and the body fluid collection container (20).
Owner:DIURIFLUX MEDICAL SA

Preparation method of traditional Chinese medicine combination for treating nephroptosis, pyelonephritis ascites and nephritis

PendingCN122321071Aeasy to useHigh cure rateNephroptosisRegimen
This invention provides a traditional Chinese medicine composition for treating renal edema, pyelonephritis with ascites, and nephritis. It consists of over 20 herbs including Atractylodes lancea, Areca catechu, Saposhnikovia divaricata, and Alisma plantago-aquatica (specific formulation details can be found in the original text). It can be prepared as pills, granules, or decoctions for oral administration. Core efficacy: 1. Promotes diuresis and reduces swelling, eliminating renal ascites; 2. Clears heat and detoxifies, anti-inflammatory and antibacterial (synergistic effect on fungal infections and cervical erosion); 3. Regulates renal function and improves abnormal uric acid metabolism. Treatment plan: Mild cases: Use five basic formulas (①-⑤) composed of Codonopsis pilosula, Poria cocos, etc., taken three times daily; Severe cases: Use a potent diuretic formula containing Akebia trifoliata and Euphorbia pekinensis (one spoonful of pills twice daily); Treatment course is approximately one month, with a follow-up examination after three months. Advantages: Cure rate reaches 90%, low recurrence rate – pure traditional Chinese medicine preparation, no significant toxic side effects; also treats complications (fungal infection, cervical lesions). This treatment plan has been clinically verified through three generations and has significant efficacy in treating renal edema, ascites, and nephritis.
Owner:李爱松

Fluid therapy based on adjusted urine output rate, and associated systems, devices, and methods

PendingUS20260137340A1SensorsUrological function evaluationDiuresisFluid replacement
This present disclosure relates to fluid therapy based on adjusted urine output rate and / or sodium output rate, and associated systems, devices, and methods. Exemplary methods can include receiving a sodium excretion input for the patient; receiving a urine output rate; determining an adjusted urine output rate based on the sodium excretion input and the urine output rate; and providing fluid therapy based on the adjusted urine output rate. By determining the amount and / or rate of the infused diuretic and / or hydration fluid based on a patient's actual sodium excretion levels, embodiments of the present technology can optimize and / or customize all or a subset of a diuretic therapy to an individual patient's physiology.
Owner:REPRIEVE CARDIOVASCULAR INC

Preparation method and application of a folk medicine wine for treating traumatic injury

PendingCN122097488AAntipyreticAnalgesicsSide effectEleutherococcus gracilistylus
This invention discloses a method for preparing and applying a Miao medicine wine for treating bruises and sprains, comprising the following steps: S1, taking and mixing *Ligusticum striatum*, safflower, *Acanthopanax senticosus*, *Smilax china*, *Ligusticum chuanxiong*, *Sargentodoxa cuneata*, *Sargentodoxa cuneata*, and sappanwood evenly; S2, soaking the mixed Chinese medicinal materials from step S1 in alcohol to obtain the medicinal wine. This invention has the effects of clearing the meridians and relieving pain, promoting blood circulation and removing blood stasis, and promoting diuresis and reducing swelling. The treatment course is short, the efficacy is good, the cure rate is high, and recurrence is not common, with an effectiveness rate of over 98%. It has great potential for widespread application. Furthermore, the medicine of this invention is simple to manufacture, convenient to use, and has no toxic side effects, and can significantly alleviate patient suffering.
Owner:GUIZHOU SHIFANG MIAO MEDICINE CO LTD

Traditional Chinese medicine composition for treating and preventing cardiovascular and cerebrovascular diseases and postoperative repair and recuperation as well as preparation method and application of traditional Chinese medicine composition

The invention discloses a traditional Chinese medicine composition for treating and preventing cardiovascular and cerebrovascular diseases and postoperative repair and recuperation based on classic famous prescription, and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The composition is prepared by combining a prescription based on coptis and colla corii asini decoction, cassia twig decoction, cinnamomum cassia and aconitum carmichaeli decoction and poria cocos, cinnamomum cassia and aconitum carmichaeli decoction, as well as poria cocos, cinnamomum cassia and aconitum carmichaeli decoction, and poria cocos and aconitum carmichaeli decoction, and poria cocos and aconitum carmichaeli decoction, and poria cocos and aconitum carmichaeli decoction, and poria cocos and aconitum carmichaeli decoction and poria cocos and In the formula, ligusticum wallichii and earthworm promote blood circulation to remove blood stasis, dredge collaterals and dissolve thrombus; hawthorn and lotus leaf are used for dissolving turbidity, lowering lipid and regulating blood fat and cholesterol; the poria cocos and the rhizoma alismatis are used for clearing damp and promoting diuresis. The whole formula has the effects of warming yang, dredging collaterals, nourishing yin and blood, promoting blood circulation to remove blood stasis, dissolving turbidity, reducing lipid, calming the heart, soothing the nerves and the like, can be used for treating cardiovascular and cerebrovascular diseases, conditioning dyslipidemia, preventing atherosclerosis and postoperative repair and nursing at the same time, is wide in application range and high in safety, can be prepared into various oral dosage forms, and has a good application prospect.
Owner:郑德章

Traditional Chinese medicine composition as well as preparation method and application thereof

The invention relates to the field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition and a preparation method and application thereof. The traditional Chinese medicine composition provided by the invention comprises astragalus membranaceus, cinnamon, semen cassiae, lotus leaves, poria cocos, lophatherum gracile, malt, hawthorn, rose, pogostemon cablin, sophora flower, semen torreya and emblic leafflower fruit. The formula takes the effects of tonifying spleen and promoting diuresis, soothing liver and regulating qi, and removing food retention and dissolving turbidity as the core, and has multiple effects of promoting urination and relieving stasis. The traditional Chinese medicine composition provided by the invention can regulate and control abnormal signal pathways of fatty liver and atherosclerosis; the compound has no obvious inhibition effect on a hepatic cell line HepG2 and has an inhibition effect on a hepatic stellate cell line LX2; the obvious lipid-lowering effect is achieved on a HepG2 high-lipid model; liver fat accumulation and liver injury in a TAA-induced zebrafish fatty liver model can be remarkably improved.
Owner:BEIJING CAPITALBIO PHARMA CO LTD +1

Formulations and methods for convenient and rapid diuresis for the treatment of edema

PCT designated stageWO2026043819A1Solution deliveryPharmaceutical non-active ingredientsAlcoholBumetanide
A method and formulations are developed for enhancing solubility and improving the permeability of bumetanide across a mucosal membrane. The formulation includes bumetanide in various water-cosolvent mixtures, which include at least one of an alcohol, polyether, glyceride, pyrrolidone, or any combination thereof. In some embodiments, the formulation has a pH of about 3.5 to about 8.0. In some embodiments, the formulation enhances the solubility and permeability of the bumetanide. Also disclosed is a use of the formulation for rapidly achieving effective bumetanide plasma concentration leading to diuresis. In some embodiments, the formulation can be administered to a subject conveniently without injection in the treatment of edema associated with heart failure or other conditions.
Owner:STRATEGIC DRUG SOLUTIONS INC

A traditional Chinese medicine composition, its preparation method and application

This invention relates to the field of traditional Chinese medicine, specifically to a traditional Chinese medicine composition, its preparation method, and its application. The traditional Chinese medicine composition, by weight, comprises the following components: 2-15 parts of ginger-processed Pinellia ternata, 2-15 parts of stir-fried Atractylodes macrocephala, 15-25 parts of Gastrodia elata, 15-25 parts of Poria cocos, 2-15 parts of dried tangerine peel, 5-15 parts of Polyporus umbellatus, 2-15 parts of cinnamon twig, 5-15 parts of Alisma plantago-aquatica, and 1-8 parts of Panax notoginseng powder. This traditional Chinese medicine composition, by combining various components in a specific ratio, allows the components to synergistically work together to achieve the effects of strengthening the spleen and resolving phlegm, promoting diuresis and eliminating turbidity, and calming the liver and unblocking the meridians. Precise proportions and dosages ensure that the entire formula exerts a synergistic effect in improving metabolism, reducing inflammation, and protecting the kidneys, thereby effectively delaying target organ damage while stabilizing blood pressure.
Owner:BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV +1

Traditional Chinese medicine composition freeze-dried flash-release tablet special for inducing diuresis and dissolving stone for dogs and cats and preparation method of freeze-dried flash-release tablet

The invention relates to the technical field of traditional Chinese medicines special for diuresis inducing and fossiling of dogs and cats, in particular to a traditional Chinese medicine composition freeze-dried flash-release tablet special for diuresis inducing and fossiling of dogs and cats and a preparation method thereof, the traditional Chinese medicine composition freeze-dried flash-release tablet comprises active components and auxiliary materials obtained by extracting the following raw material medicines in parts by weight: 420 parts of plantain herb, 160 parts of rhizoma alismatis, 20 parts of eucommia ulmoides and 20 parts of rhizoma smilacis glabrae. The active component of the plantain herb is a 95% ethanol ultrasonic extract, the active component of the rhizoma alismatis is a 60% ethanol reduced pressure reflux extract, and the active components of the eucommia ulmoides and the rhizoma smilacis glabrae are water decoction extracts. Active substances which are easy to damage when being heated are effectively reserved, so that the effects of inducing diuresis and treating stranguria are fully exerted; and the rhizoma alismatis is extracted by using ethanol with a specific concentration, so that the effect of promoting water discharge is accurately exerted on the premise of controlling the dosage.
Owner:CHONGQING XINONGDA KEXIN ANIMAL PHARM CO LTD

Goutrelief granules

PendingCN122342790APlantago asiaticaRapid pulse
This invention relates to the field of traditional Chinese medicine technology, specifically to a granule for promoting urination and eliminating stones, its preparation method, and its application. The granule comprises the following ingredients: *Lysimachia christinae*, *Pyrrosia lingua*, *Cynanchum paniculatum*, talc, stir-fried chicken gizzard lining, *Polygonum aviculare*, *Dianthus superbus*, *Plantago asiatica*, *Tetrapanax papyriferus*, *Poria cocos*, *Coix lacryma-jobi*, *Paeonia lactiflora*, vinegar-processed *Corydalis yanhusuo*, *Astragalus membranaceus*, and *Achyranthes bidentata*. The entire formula integrates clearing heat and promoting urination, dissolving stones, tonifying qi and relieving pain, and guiding the medicine downwards. It primarily focuses on purging while supplementing with tonifying, achieving the combined effects of clearing heat and promoting diuresis, and dissolving stones. It is used for damp-heat accumulation, stone accumulation, or combined with deficiency of vital energy leading to urinary tract infections, stones, or hematuria. Symptoms include frequent urination, burning and stinging pain, yellow or reddish urine, abdominal cramps, difficulty urinating or stones in the urine, red tongue with yellow or greasy coating, and a slippery and rapid pulse. This composition has the effects of clearing heat and promoting diuresis, relieving strangury and expelling stones. It is used for heat strangury, stone strangury and hematuria caused by damp-heat accumulation, with symptoms such as frequent urination, burning and stinging pain, yellow or reddish urine or blood in urine, lower back and abdominal colic, difficulty in urination or gravel in urine, red tongue with yellow or yellow and greasy coating, and slippery and rapid pulse.
Owner:玉林市中医医院

Chinese medicinal preparation based on Chinese angelica and preparation method thereof

The invention relates to the technical field of traditional Chinese medicine, and particularly discloses a traditional Chinese medicine preparation based on radix angelicae sinensis and a preparation method thereof.The traditional Chinese medicine preparation is prepared from, by weight, radix angelicae sinensis, radix astragali, radix dipsaci, semen euryales, fructus rosae laevigatae, radix achyranthis bidentatae, radix bupleuri, corn stigma, seaweed and an emulsifying auxiliary agent; the emulsifying aid is innovatively added into the traditional Chinese medicine compound, and the emulsifying aid and volatile oil extracted from a traditional Chinese medicine formula are mixed and emulsified and then mixed with thick paste extracted from traditional Chinese medicine components to prepare the traditional Chinese medicine preparation. The obtained traditional Chinese medicine preparation not only improves liver depression and blood deficiency caused by diabetic renal anemia and relieves the burden of kidneys through the synergistic effect of nourishing liver and kidney, regulating qi and blood, inducing diuresis to alleviate edema, resisting oxidation and the like, but also can enhance the tonifying effect of the angelica sinensis, thereby achieving the purposes of treating diabetic renal anemia and reducing complications.
Owner:BEIJING LANGZHI ENTERPRISE MANAGEMENT CO LTD +1

A traditional Chinese and Tibetan medicine composition with functions of improving microcirculation and promoting diuresis and removing dampness.

This invention provides a traditional Chinese and Tibetan medicine composition with functions of improving microcirculation and promoting diuresis and removing dampness. Animal experiments revealed that, in terms of pharmacological activities such as improving microcirculation and promoting diuresis and removing dampness, the removal of ephedra significantly reduced the aforementioned pharmacological activities in the standard formula of Wuwei Ganlu. However, the addition of ginger, cinnamon twig, and hot spring water significantly enhanced the overall pharmacological effects of the formula, specifically by promoting microcirculation, reducing the incidence of drug-induced renal edema, increasing glomerular filtration rate, and improving the relative expression level of the aqp3a gene related to aquaporin 3 (AQP3).
Owner:SHANDONG JINHE DRUG RES DEV

Unilateral preparation for eliminating urine protein based on ovate catalpa fruit and application of unilateral preparation

The invention discloses a Chinese catalpa fruit-based unilateral preparation for eliminating urine protein and application thereof, and belongs to the technical field of traditional Chinese medicine, the active ingredient of the unilateral preparation is extracted from a single medicinal material of Chinese catalpa fruit, and the unilateral preparation can contain pharmaceutically acceptable auxiliary materials. The single preparation can be prepared into four dosage forms of oral liquid, tablets, dripping pills and granules so as to meet different clinical requirements. Animal experiments prove that the single preparation can effectively eliminate urine protein and improve the renal function through four synergistic mechanisms of anti-inflammation, anti-oxidation, improvement of the renal function, protection of podocyte and immunoregulation and diuresis, and is suitable for treating proteinuria accompanied by nephropathy. The preparation provided by the invention has the characteristics of single formula, easy quality control and various dosage forms, and provides a traditional Chinese medicine scheme with an exact curative effect for clinically treating related diseases.
Owner:SHENYANG PHARMA UNIV

Urine analyzer

A urine analysis device (1) is provided for analyzing a urine sample to determine a physicochemical characteristic value of the urine sample, and comprises a first sampler module (2) configured to be placed in fluid pathway connection with a user; the first sampler module (2) comprises a first drainage tube (20) comprising a containing portion (20a) defining a predetermined volume and configured to hold a first portion of urine, and a discharge portion (20b) configured to discharge a second portion of urine out of the first sampler module (2); a diuretic bag (3) in fluid passage connection with at least the discharge portion (20b) and configured to collect a second portion of the urine; an analysis device (4) placed in fluid pathway connection with the containing portion (20a) and configured to analyze at least part of the first urine portion; a control mechanism (5) operably connected to the analysis device (4) and configured to process at least data collected by the analysis device (4); and a support structure (10) configured to support the first sampling module (2), the diuretic bag (3), the analysis device (4) and the control mechanism (5); wherein at least the diuretic bag (3) is removably defined to the support structure (10) and is decoupled from the first sampling module (2).
Owner:KURES GMBH

Composition as well as preparation method and application thereof in preparation of product with uric acid reducing effect

PendingCN121818782ATaking care of protectionInhibition of reabsorptionOrganic active ingredientsAntipyreticBiotechnologyVitamin b6
The invention belongs to the technical field of biological medicine, and particularly discloses a composition, a preparation method thereof and application of the composition in preparation of a product with a uric acid lowering effect, and the composition comprises the following components in percentage by mass: 70.9-79% of a natural extract, 20-30% of celery seeds and 0.1-1% of vitamin B6. The natural extract comprises an acid cherry extract, a chrysanthemum morifolium extract and a gardenia extract in a mass ratio of 1: (1-2): (1-3). According to the composition disclosed by the invention, medicinal and edible natural plant components such as fructus gardeniae, chrysanthemum morifolium ramat, sour cherries and celery seeds are specifically combined with vitamin B6, and the formula aims at a source (for inhibiting XOD) of uric acid generation and an export (for promoting diuresis and inhibiting reabsorption) of excretion at the same time, and also gives consideration to anti-inflammation and kidney protection.
Owner:GUANGDONG TIMES FOOD & LIFE HEALTH RES CO LTD

Flavored lung-heat-clearing traditional Chinese medicine compound and preparation method thereof

The invention discloses a modified lung heat clearing decoction traditional Chinese medicine compound and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine, the compound comprises the following components by mass: 6 g of raw ephedra, 10 g of almond, 30 g of gypsum, 6 g of raw licorice, 10 g of platycodon grandiflorum, 10 g of burdock, 10 g of scutellaria baicalensis, 15 g of polygonum cuspidatum, 10 g of schizonepeta, 10 g of notopterygium root, and 10 g of stiff silkworm. According to the traditional Chinese medicine composition, exterior syndrome relieving medicines are added to export pathogenic factors, meanwhile, medicines for ventilating the lung, depressing qi, relieving sore-throat and inducing resuscitation are added to quickly relieve main symptoms and recover lung functions, and medicines with the effects of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, promoting diuresis and dredging collaterals are selected to more comprehensively inhibit viruses and relieve pathological damage of organisms; and a co-decoction granule technology is adopted, so that the drug effect is stable, and the'unification 'and the optimal drug effect of a complex prescription are guaranteed.
Owner:DONGZHIMEN HOSPITAL OF BEIJING UNIV OF CHINESE MEDICINE

Traditional Chinese medicine composition for treating immune-related glomerular diseases and application thereof

The traditional Chinese medicine composition disclosed by the invention adopts a method of warming yang and relieving exterior syndrome to achieve the effects of freeing lung and inducing diuresis, tonifying spleen and warming kidney, and strengthening defensive qi and diminishing swelling, and is prepared to be used for treating the immune-related glomerular diseases, especially membranous nephropathy and minimal lesion nephropathy. The traditional Chinese medicine composition is a pure traditional Chinese medicine preparation, clinical observation and in-vivo and in-vitro basic tests show that the prescription can remarkably improve edema, massive proteinuria, hypoproteinemia and the like, meanwhile, compared with the prior art, the traditional Chinese medicine composition has a better effect on symptoms such as stomachache and diarrhea, has an anti-inflammatory effect and does not have obvious side effects in clinical application. The traditional Chinese medicine composition has an excellent effect on patients suffering from membranous nephropathy and minimal lesion nephropathy caused by syndrome differentiation of spleen-kidney yang deficiency, internal rheumatism and water-fluid overflowing.
Owner:BEIJING CHINESE MEDICINE HOSPITAL AFFILIATED CAPITAL MEDICAL UNIV

A traditional Chinese medicine composition with detoxifying and uterine-warming effects and its application in the preparation of external products.

This invention belongs to the field of traditional Chinese medicine (TCM) technology, specifically relating to a TCM composition with detoxifying and uterus-warming effects and its application in the preparation of external products. The medicinal component of this external TCM product is composed of fenugreek, amethyst, rose, pomegranate seed, centella asiatica, long pepper, five-finger peach, lycopodium, litchi seed, and achyranthes bidentata. Animal experiments show that this product can significantly reduce the number of writhing movements in animals with cold-induced blood stasis type dysmenorrhea, lower COX-2 and PGE2 levels in the uterus, and improve peritoneal inflammation, demonstrating good detoxifying, blood stasis-removing, menstruation-regulating, and pain-relieving effects. Regarding blood rheology, it exhibits the effects of inhibiting platelet aggregation, dilating blood vessels, reducing blood viscosity, and balancing TXA2 and PGI2 levels, reflecting its effects of warming the kidneys and uterus, and strengthening the body's foundation. In summary, the TCM composition of this invention and its prepared external product can warm the kidneys and uterus, promote diuresis and eliminate turbidity, providing a novel TCM external application solution for the clinical treatment of cold-induced blood stasis type dysmenorrhea.
Owner:GUANGDONG TEYI HEALTH RESEARCH CO LTD

Traditional Chinese medicine composition with functions of regulating qi and promoting digestion

The invention discloses a traditional Chinese medicine composition with functions of regulating qi and promoting digestion, relates to the technical field of traditional Chinese medicines, and is technically characterized in that the traditional Chinese medicine composition is prepared from the following components in parts by weight: 3-10 parts of poria cocos, 3-10 parts of dried dendrobe, 5-15 parts of malt, 5-6 parts of pawpaw, 6-40 parts of codonopsis pilosula, 5-10 parts of bighead atractylodes rhizome, 4-6 parts of hawthorn, 3-6 parts of fructus forsythiae, 3-6 parts of massa medicata fermentata fujianensis, 3-6 parts of jujube and 3-6 parts of pericarpium citri reticulatae. According to the traditional Chinese medicine composition, various traditional Chinese medicines are combined together, the properties of the traditional Chinese medicines are mutually blended, the effects are more comprehensive, and the traditional Chinese medicine composition can enhance spleen and stomach functions, relieve dyspepsia, adjust gastrointestinal tract balance and induce diuresis to reduce edema; a plurality of components in various traditional Chinese medicines are matched with one another, so that the medicine properties of the various traditional Chinese medicines are enhanced, and the effects are better exerted.
Owner:REHABILITATION HOSPITAL AFFILIATED TO CHONGQING MEDICAL UNIV

Traditional Chinese medicine extract composition for assisting in reducing uric acid and preparation method of traditional Chinese medicine extract composition

PendingCN121059742APowder deliverySkeletal disorderDiseaseJoint arthralgia
The invention discloses a traditional Chinese medicine extract composition for assisting in reducing uric acid and a preparation method, and relates to the technical field of traditional Chinese medicine compositions, the traditional Chinese medicine extract composition comprises poria cocos, cichorium intybus, radix puerariae, gentiana macrophylla, rhizoma smilacis glabrae, Tibetan capillary, emblic leafflower fruit, glabrous sarcandra herb, Chinese starjasmine stem, wild buckwheat rhizome and white gourd. The traditional Chinese medicine extract composition breaks through the limitation of single existing uric acid reducing mechanism, plays a role in uric acid generation and excretion links, regulates a key pathway of uric acid metabolism through traditional Chinese medicine components to reduce uric acid generation, promotes urination to promote uric acid excretion, inhibits inflammatory mediator release and relieves oxidative damage by means of glabrous sarcandra herb and wild buckwheat rhizome components, and has a good application prospect. According to the traditional Chinese medicine preparation, the effect of multi-link synergistic effect of reducing uric acid, resisting inflammation and resisting oxidation is achieved, meanwhile, the blood uric acid level is reduced, the gout arthralgia symptom is relieved, the problem that an existing traditional Chinese medicine preparation cannot give consideration to comprehensive curative effect is solved, the requirement of a patient for comprehensive improvement of the illness state is met, and the overall effectiveness of treatment is improved.
Owner:CATCH BIO SCI & TECH

Reduced flow catheter for liquid overload treatment

Disclosed herein is a vessel reshaping device configured to reshape a vessel along a single axis and modulate blood flow therethrough. The vessel reshaping device generally consists of a frame that can be transformed into an expanded configuration and can temporarily reshape a vessel, such as the inferior vena cava (IVC), along a single axis perpendicular to the longitudinal axis. The more the reshaping device expands, the more the cross-sectional area decreases, and in turn, the more the flow through the vessel decreases. Thus, altering the blood flow to the heart can improve the symptoms of hypervolemia, thereby increasing diuretic effect and improving the symptoms of congestive heart failure.
Owner:BARD PERIPHERAL VASCULAR INC