28 results about "Trigonella" patented technology

The invention discloses a traditional Chinese medicine composition for treating type 2 diabetes and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from, by weight, 11-15 parts of radix acanthopanacis semticosi, 5-15 parts of male silkworm moth, 7-17 parts of white ginseng, 5-11 parts of rhizoma polygoni cuspidati, 15-25 parts of rhizoma coptidis, 1-5 parts of cortex cinnamomi, 11-15 parts of fructus ligustri lucidi, 11-15 parts of common fenugreek seed, 7-17 parts of lithocarpus litseifolius, 3-7 parts of raw radix astragali and 1-3 parts of wild lucid ganoderma. , 3-9 parts of tribulus terrestris and 11-17 parts of nigella nigra seeds. The traditional Chinese medicine composition has the effect of balancing and stabilizing blood sugar, is short in treatment course, quick in effect and free of toxic and side effects, and has an excellent curative effect on treating diabetic complications.

The present invention relates to an oral extract composition comprising Shatavari (Asparagus racemosus Willd.) and Fenugreek (Trigonella foenum-graecum L.) extract composition, and its process of preparation. Also relates to the oral extract composition formulation comprising with synergistic combinations of the Shatavari (Asparagus racemosus Willd.) and Fenugreek (Trigonella foenum-graecum L.) in suitable doses and at least one nutraceutically and / or pharmaceutically accepted excipient for, improvement, and maintenance of women health more preferably in improving of hot flashes, night sweats, poor sleep, anxiety, sexual dysfunction, mood changes, Genitourinary symptoms in overall improving the quality of life, serum estradiol, progesterone, follicle stimulating hormone (FSH), and cortisol during the period of menopause (perimenopause and menopause). The oral extract composition formulation comprising with synergistic combinations of the Shatavari (Asparagus racemosus Willd.) and Fenugreek (Trigonella foenum-graecum L.) in suitable doses and at least one nutraceutically and / or pharmaceutically accepted excipient is used for improving Brain-derived neurotrophic factor (BDNF) levels in women during the period of menopause. The present invention, further related to the extraction process of Shatavari (Asparagus racemosus Willd.) and Fenugreek (Trigonella foenum-graecum L.), also provides the process for the preparation of formulation composition. This invention further relates to the extraction process from Shatavari (Asparagus racemosus Willd.) and Fenugreek (Trigonella foenum-graecum L.) either as individual herbs or co-extraction of the two herbs or mixing the extracts at various stages of the individual extracts.

This invention discloses a traditional Chinese medicine formula for preventing and treating feline urinary tract diseases, its preparation method, and its application. The formula consists of the following components in parts by weight: 15-25 parts of Psoralea corylifolia, 15-25 parts of Alpinia oxyphylla, 10-20 parts of Trigonella foenum-graecum, 5-15 parts of Zea mays, 5-15 parts of Juncus effusus, 10-20 parts of Dioscorea hypoglauca, 10-20 parts of Phellodendron chinense, 10-20 parts of Lonicera japonica, 5-15 parts of Paeonia lactiflora, and 5-15 parts of Glycyrrhiza uralensis. The traditional Chinese medicine formula provided by this invention has diuretic and urinary tract mucosal repairing effects. It can effectively relieve symptoms such as urinary stones, painful urination, hematuria, or gravel in the urine caused by damp-heat in the lower abdomen. It promotes the repair of the urinary tract mucosa in animals with urinary tract diseases, alleviates inflammatory responses, and prevents the formation of crystals in the urine.

The invention provides a preparation method of mannan oligosaccharide, and belongs to the field of biological activity preparation. The preparation method comprises the following steps: fenugreek pretreatment, immobilized enzyme preparation, enzymolysis extraction and extraction. The yield of the mannan oligosaccharide prepared by the method is 40.23 to 41.05 percent, the yield is high, the purity of the crude mannan oligosaccharide is 88.51 to 90.12 percent, the purity is high, the purity of the extracted mannan oligosaccharide is 95.41 to 97.51 percent, and the purity is high; after the immobilized enzyme is oscillated for 24 hours at the speed of 80 r / min in a water tank, the residual enzyme activity is 83.6-85.7%, and the firmness degree of combination of the enzyme protein of the immobilized enzyme and the carrier is high; after 1g of the immobilized enzyme is stored in an environment of 5 DEG C for 240 hours, the residual enzyme activity is 79.9-81.3%, and the storage performance of the immobilized enzyme is strong; after the immobilized enzyme is recycled for six times, the enzyme activity is 68.7-70.5%, the utilization rate of the enzyme is improved, the loading capacity of the carrier is 5.7-6.1%, and the loading capacity is high.

The invention relates to a Chinese herbal medicine extracellular vesicle composition as well as a preparation method and application thereof. The Chinese herbal medicine extracellular vesicle composition comprises five or more of herba violae extracellular vesicles, rhizoma bletillae extracellular vesicles, herba verbenae extracellular vesicles, radix aconiti kusnezoffii extracellular vesicles, radix sophorae subprostratae extracellular vesicles, rhizoma curcumae extracellular vesicles, rhizoma sparganii extracellular vesicles and herba agrimoniae extracellular vesicles. Wherein the Chinese herbal medicine extracellular vesicle composition comprises European verbena extracellular vesicles and hairyvein agrimony extracellular vesicles. The Chinese herbal medicine extracellular vesicle composition provided by the invention can safely and efficiently relieve neck / shoulder / waist / leg / joint pain.

The invention relates to the technical field of natural product extraction, and discloses a green preparation method of high-purity trigonelline. The method comprises the following steps: (1) performing first treatment on a degreased fenugreek seed raw material in an ethanol water solution under 400-500MPa, and removing a solvent to obtain a mixture I; (2) carrying out second treatment on the mixture I in an aqueous two-phase system, and separating to obtain an upper phase solution rich in trigonelline; and (3) sequentially performing ultrafiltration membrane impurity removal, nanofiltration membrane concentration, resin purification, concentration crystallization and drying on the upper-phase solution to obtain the high-purity trigonelline. The method provided by the invention is efficient and low in consumption, the obtained trigonelline is high in purity, and high-selectivity extraction and purification of the trigonelline are realized.

The present invention relates to a Chinese herbal extracellular vesicle composition, its preparation method, and application. The Chinese herbal extracellular vesicle composition comprises five or more of the following: extracellular vesicles from Rhizoma Corydalis, Bletilla striata, Verbena officinalis, Aconitum kusnezoffii, Sophora flavescens, Curcuma zedoaria, Trigonella ternatea, and Agrimoniae scabra. The Chinese herbal extracellular vesicle composition comprises Verbena officinalis and Agrimoniae scabra. The Chinese herbal extracellular vesicle composition provided by the present invention can safely and effectively relieve neck, shoulder, waist, leg, and joint pain.

The invention discloses fenugreek formula granules and a preparation method thereof. The preparation method of the trigonella foenum-graecum formula granules comprises the following steps: taking 100 parts by mass of trigonella foenum-graecum decoction pieces, adding 2000-3000 parts by mass of water, carrying out warm immersion extraction, and collecting liquid medicine; concentrating the liquid medicine, filtering, collecting paste, and performing spray drying to obtain fenugreek powder; and adding a proper amount of excipient to 20 parts by mass into the obtained medicinal powder, uniformly mixing, granulating by a dry method, and sieving to obtain the fenugreek formula granules. By adopting a warm immersion extraction process, the dissolution of mucus in fenugreek can be effectively avoided, and the dissolubility of the fenugreek formula granules can be improved, so that the dissolubility of the product meets the requirements of Chinese Pharmacopoeia standards.

The invention discloses a traditional Chinese medicine composition for treating femoral head necrosis, a traditional Chinese medicine preparation and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. Aiming at the problems of western medicine and traditional Chinese medicine treatment for femoral head necrosis at present, the traditional Chinese medicine composition comprises the following traditional Chinese medicine components by weight: 15g of salvia miltiorrhiza, 10g of ligusticum wallichii, 10g of angelica sinensis, 12g of red paeony root, 6g of ground beetle, 3g of leech, 7g of rhizoma sparganii, 7g of curcuma zedoary, 10g of epimedium, 10g of dipsacus root, 4g of cinnamon and 6g of liquorice, after each traditional Chinese medicine component is weighed and soaked, the traditional Chinese medicine components are respectively decocted twice, mixed, filtered, concentrated and bagged. The traditional Chinese medicine composition disclosed by the invention is unique in formula, is used for tonifying liver and kidney, promoting blood circulation to remove meridian obstruction, improving femoral head blood circulation and promoting femoral head necrosis repair, is remarkable in curative effect and small in side effect, and can be used for hip protection treatment of patients suffering from femoral head necrosis in early and middle periods and treatment of patients who are unwilling to accept hip replacement surgery in late periods.

The invention relates to the technical field of medicines, in particular to application of creeping woodbetony herb and an extract thereof in preparation of a medicine for treating liver function impairment. The invention provides the following two applications: (1) preventing / treating cell injury and tissue injury caused by oxidation and inflammation; and (2) preventing / treating acute and chronic liver injury. It is fully verified that the creeper creeper extract has an obvious liver protection effect and dose dependence, and liver injury can be obviously protected. In addition, the creeper creeper and the specific creeper creeper extract disclosed in the invention can also reduce the release of alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphatase (ALP), significantly reduce the degree of necrosis of liver cells and reduce the degree of inflammation infiltration.

The invention relates to a composition containing i) a DPP-4 inhibitor selected from an extract of dandelion (Taraxacum officinale), an extract of white mulberry (Morus alba), an extract of bitter melon (Momordica charantia), a hydrolysate of yeast (Saccharomyces cerevisiae), an extract of garlic (Allium sativum), an extract of grape (Vitis vinifera), an extract of turmeric (Curcuma longa), an extract of horseradish tree (Moringa oleifera) and an extract of fenugreek (Trigonella foenum-graecum); and ii) a GLP-1 analogue selected from a hydrolysate of yeast (Saccharomyces cerevisiae), a white mulberry (Morus alba) extract, a yerba mate (Ilex paraguariensis) extract, an Arabica coffee (Coffea arabica) extract, a purslane (Portulaca oleracea) extract, a bitter melon (Momordica charantia) extract, a lager flower (Lagerstroemia speciosa) extract, an apple (Malus domestica) extract, a cinnamon (Cinnamomum verum) extract and a fenugreek (Trigonella foenum-graecum) extract; and iii) a GLP-1 secretion enhancer selected from inulin, gum arabic, an extract of bitter melon (Momordica charantia), an extract of purslane (Portulaca oleracea), an extract of common barberry (Berberis vulgaris), an extract of Arabica coffee (Coffea arabica), an extract of Siberian angelica (Angelica dahurica), an extract of turmeric (Curcuma longa) and an extract of fenugreek (Trigonella foenum-graecum), where at least one ingredient is selected from each group i)-iii) and a total of at least three different ingredients are selected.

Described herein are compositions and methods that modulate or enhance the taste perceptions of a subject. Aspects of the present disclosure relate to compositions and methods of use comprising a flavonolignan, a steroid saponin, an iridoid glycoside, amentoflavone, a polyisoprenylated benzophenone, a phenylpropanoid, a pheylethanol derivate, a glycoside and / or analogs thereof (for example, a glycosylation molecule of an aglycone, an aglycone of a glycosylated molecule, or a further glycosylated molecule of a glycosylated molecule) obtained from a plant extract such as a Silybum marianum (milk thistle) extract, an Asparagus racemosus extract, a Smilax china extract, a Rehmannia glutinosa root extract, a Selaginella tamariscina extract, a Garcinia indicia extract, a Garcinia cambogia extract, a Trigonella foenum graecum L. extract, a Rhodiola rosea root or rhizome extract and / or other plant sources which are used for enhancing a subject's taste perception of sweetness, mouthfeel, astringency, bitterness, alcohol, carbonation, spice, salt, sourness, umami, tingling, numbing or cooling, harshness, pungency, burning, freshness, ripeness, juiciness, for increasing the amount of carbonation bubbles or decreasing the carbonation bubble size of a carbonated beverage, or for masking off-tastes

The process for the production of herbal, halal and perfume free shampoo was developed keeping in view the religious sanctity of Ehram during Hajj and Umrah. The shampoo composition comprises of heating and vigorous mixing of diethyl amides of coconut oil 7.5%. Olive oil 0.5%, sodium cocoamide 15.0% and isopropyl myristate 1.5% with de-ionized water 73.78% at 70-75°C for 30 minutes. Herbal extracts of Calendula officinalis 0.08% and Trigonella .foenum-graecum 0.08%. along with Aloe vera gel 1.0%. Olive and Wheat germ oils 0.01%, and preservatives 0.1% were added to this mixture after cooling to 40-45°C. The pH was maintained at 6.8-7.2 with 1% solution of citric acid in water. Finally apple green food color was added to the mixture. It was observed that this formulation is not only effective as cleansing agent but provides excellent conditioning of scalp resulting in the check of hair loss. The present invention gives new life, lustrous thick look and extra bounce to hair. The product can be used in the state of Ehram, as it is perfume free and halal.

The invention discloses selenium-rich liquid medicine and production equipment thereof. The selenium-rich liquid medicine comprises a basic nutrient solution and a composite nutrient solution, the basic nutrient solution is prepared from 500 parts of water, 10 parts of chelated organic selenium, 8 parts of animal source amino acid, 8 parts of a water-soluble fertilizer aid, 5 parts of sodium alginate, 3 parts of soluble salt and 2 parts of a stabilizer; the compound nutrient solution is prepared by decocting 5 parts of astragalus membranaceus, 5 parts of nutgrass flatsedge, 1 part of aster, 1 part of atriplex canescens, 5 parts of liquorice and 10 parts of hawthorn, filtering out medicine residues to obtain primary medicine liquid, then adding 2 parts of humic acid, 2 parts of L-proline, 1 part of magnesium sulfate and 1 part of copper sulfate into the primary medicine liquid, and stirring and mixing to obtain the compound nutrient solution; the basic nutrient solution and the composite nutrient solution are mixed together according to the proportion of 15: 1 to obtain the selenium-rich liquid medicine, the selenium-rich liquid medicine relates to the technical field of selenium-rich products, the selenium-rich liquid medicine can be directly sprayed to crops and also can be sprayed to soil, the activity of the crops is improved from the two aspects, and the absorption effect of the crops on the selenium-rich nutrient solution is improved.

The invention discloses medicinal liquor for preventing and treating liver and kidney deficiency type osteoarticular degenerative change and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine compositions. The medicinal liquor for preventing and treating liver and kidney deficiency type bone joint degenerative change is prepared from the following raw materials in parts by weight: 12 to 18 parts of herba epimedii extract, 12 to 18 parts of fructus lycii, 10 to 15 parts of fructus psoraleae, 10 to 15 parts of semen cuscutae, 10 to 15 parts of herba cynomorii, 10 to 15 parts of radix morindae officinalis, 8 to 12 parts of fructus cnidii, 8 to 12 parts of herba cistanche, 8 to 12 parts of radix astragali seu hedysari, 8 to 12 parts of caulis spatholobi, 6 to 12 parts of radix angelicae sinensis, 6 to 12 parts of rhizoma drynariae, 6 to 12 parts of radix dipsaci, 6 to 10 parts of semen astragali complanati, 6 to 10 parts of cortex eucommiae, 6 to 10 parts of fructus jujubae and 800 to 1200 parts of pure The medicinal liquor can significantly improve clinical symptoms, pain degree and life quality of patients with liver and kidney deficiency type knee osteoarthritis, is good in safety and free of obvious serious adverse reactions, and has a good clinical application prospect.

The invention discloses a primer combination and an identification method for identifying the types and producing areas of medicinal plants, namely gynura and mukdenia, and belongs to the technical field of biology. Comprising a primer group 1 and a primer group 2, the primer group 1 is composed of a forward primer as shown in SEQ ID NO. 1 and a reverse primer as shown in SEQ ID NO. 2; and the primer group 2 is composed of a forward primer as shown in SEQ ID NO.3 and a reverse primer as shown in SEQ ID NO.4. The primer group 1 comprises a forward primer as shown in SEQ ID NO.3 and a reverse primer as shown in SEQ ID NO.4. The invention develops a primer combination and an identification method for identifying the types and the producing areas of the single-root grass and the mukdenia. The chloroplast molecular marker technology is applied to accurately identify species with a more sensitive and efficient identification means, and compared with traditional phenotype identification, the identification result is more accurate, reliable, rapid and simple, and the method is suitable for large-scale popularization and application. The method can be applied to the aspects of rapid identification, pedigree geography research, variety intellectual property protection, molecular marker-assisted breeding and the like of gynura and mukdenia species.

The traditional Chinese medicine composition is prepared from the following raw material components in parts by weight: 10 to 20 parts of herba lysimachiae, 5 to 15 parts of rhizoma atractylodis, 5 to 15 parts of pericarpium citri reticulatae viride, 5 to 15 parts of rhizoma polygoni cuspidati, 5 to 15 parts of radix cyathulae, 5 to 15 parts of trifoliate orange pears, 5 to 15 parts of rhizoma sparganii, 5 to 15 parts of rhizoma curcumae, 5 to 15 parts of semen vaccariae and 5 to 15 parts of spina gleditsiae. The formula is strict, the monarch, minister, assistant and guide are clear, the medicine flavor is concise, the medicine property is mild, compared with similar medicines on the market, the Lianqing Qingqing formula (an original name of a stone eliminating formula) focuses on regulating qi, activating blood, removing blood stasis and eliminating stone on the basis of clearing heat and promoting diuresis, has the advantages of few toxic and side effects, high safety, small economic burden and the like, and has better transformation and application prospects.

Provided are botanical or bacterial extracts and methods of treating skin and other tissues by applying certain botanical or bacterial extracts, such as from Acronychia acidula, Licaria vernicosa, Calendula officinalis, Trigonella foenum-graecum or Actimomyces bacteria, to the skin or other tissue. In particular, provided are methods of treating signs of skin aging, comprising topically applying to skin in need of treatment for signs of skin aging a composition comprising 3-(4-farnesyloxyphenyl)-propionic acid and / or its ethyl ester.

The invention disclosed herein is a synergistic herbal composition comprising extracts of Mucuna pruriens, Cynara cardunculus, Trigonella foenum graecum, Withania somnifera and L-arginine along with pharmaceutically acceptable excipients, having libido enhancing, testosterone levels increasing and ejaculation delaying properties. The present invention also disclosed herein a process for preparation of said composition.

The invention belongs to the technical field of traditional Chinese medicines, and provides a traditional Chinese medicine composition for conditioning sub-health and a preparation method thereof. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: 20-30 parts of eucommia ulmoides, 10-20 parts of dipsacus root, 10-20 parts of radix achyranthis bidentatae, 8-15 parts of frankincense processed with vinegar, 8-15 parts of myrrh processed with vinegar, 5-12 parts of asarum, 5-12 parts of ligusticum wallichii, 5-12 parts of radix angelicae, 5-12 parts of angelica sinensis, 3-5 parts of semen strychni, 5-15 parts of prepared kusnezoff monkshood root, 5-15 parts of radix aconiti preparata, 10-20 parts of radix clematidis, 5-12 parts of common fenugreek seed, 5-12 parts of cassia twig, 5-12 parts of rosin, 5-12 parts of vitex negundo, 5-12 parts of fructus evodiae and 5- 5-12 parts of notopterygium root and 5-12 parts of radix angelicae pubescentis; a multi-target mechanism is formed through cooperation of multiple medicinal materials, and the purposes of efficiently improving sub-health symptoms, effectively guaranteeing medication safety and improving the drug effect stability are achieved.

The invention discloses a method for establishing a fenugreek efficient regeneration system, and belongs to the technical field of medicinal plant tissue culture. The establishment method comprises the following steps: (1) inoculating a fenugreek explant into a primary induction culture medium containing 5-azacytidine, spermidine and fluridone, and carrying out induction culture to generate an adventitious bud; (2) dividing the adventitious buds, and then transferring the adventitious buds into a proliferation culture medium containing trehalose, paclobutrazol and uridine for culture to realize amplification of the adventitious buds; and (3) transferring the stem segments obtained by multiplication culture into a rooting culture medium containing sodium nitroprusside and jasmonic acid methyl ester for culture, and inducing rooting. According to the established efficient sterile rapid propagation system for fenugreek, the adventitious bud differentiation rate reaches 91.3%, the propagation coefficient is 10.8, the rooting rate reaches 97.5%, the propagation speed is high, high-quality seedlings can be produced on a large scale, and meanwhile the yield and quality are improved.

A traditional Chinese medicine compound for treating blood stasis arthralgia type osteoarthritis belongs to the field of traditional Chinese medicine preparations and comprises 8 g of polygonum cuspidatum, 10 g of rhizoma sparganii, 10 g of turmeric, 10 g of motherwort, 10 g of artemisia anomala, 10 g of rhizoma curculiginis, 10 g of ramulus mori, 10 g of lycopodium clavatum, 10 g of bungarus parvus, 8 g of radix angelicae, 10 g of codonopsis pilosula, 10 g of semen coicis, 8 g of scutellaria baicalensis, 8 g of honeysuckle and 8 g of fructus forsythiae. All the medicines are put into a non-woven fabric bag to be sealed and put into a container, and water is added for boiling. Effective components of the traditional Chinese medicines are separated out by heating to prepare the fumigation and washing formula, and the effects of promoting blood circulation to remove blood stasis and activating meridians to stop pain are achieved when the fumigation and washing formula is used.

The invention provides a green prevention and control method for diseases and insect pests of silage corn in an oasis agricultural district, and belongs to the technical field of prevention and control of crop diseases and insect pests, the prevention and control method comprises the following steps: 1) before sowing, corn seeds are coated, and the coating preparation comprises benfuracarb, fludioxonil, rosin.ethylidene.brassica campestris and Trigonella seseloides; 2) corn large horn mouth period: spraying a first preparation on leaf surfaces; the composition is prepared from the following raw materials: benzoyl, propiconazole, abamectin, chlorobenzoyl, red, ethylidene.brassica, Tubajia and Anfule; (3) in the early stage of corn spinning, spraying a second preparation, namely benzyl azoxystrobin, SYP-9625, tetrachlorantraniliprole, Toubajia and Anfule, on leaf surfaces. According to the prevention and control method, field diseases and insect pests are effectively controlled, and the prevention and control effect reaches 62.6%; the plant height, the stem diameter and the fresh grass weight of the silage corn are respectively increased by 17.8%, 11.4% and 9.2%, and the yield of the fresh grass per mu reaches 5641.2 Kg; the preparation is safe to corn seeds and plants, meanwhile, the field pesticide application frequency is reduced, the prevention and treatment cost is reduced, and the preparation can be popularized and used.

The invention relates to the technical field of livestock breeding, and provides application of fenugreek leaves in preparation of an animal feed additive. Multiple core technical effects can be achieved only by adding the fenugreek leaves into the basic ration of the yellow feather broiler chickens, the growth of the broiler chickens can be promoted, the immunity of the organism and the meat flavor can be improved, liver lipid deposition can be reduced, the blood fat level can be reduced, and liver metabolite composition can be adjusted; meanwhile, fatty acid generation is reduced by regulating and controlling liver lipid metabolism related gene expression, and liver lipid metabolism is improved from the source. Meanwhile, it has been determined that the optimal addition amount of the fenugreek leaves is 0.5-2 wt% of the basic ration, and a solid theoretical basis is provided for popularization and application of the fenugreek leaves as a traditional Chinese medicine feed additive in healthy breeding of broiler chickens.

The invention discloses a traditional Chinese medicine composition for improving cognitive impairment of diabetes as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following raw material medicines: radix rehmanniae recen, Chinese yam, dogwood, poria cocos, rhizoma alismatis, moutan bark, cassia twig, astragalus membranaceus, codonopsis pilosula, fenugreek and purslane. The invention also discloses a preparation method of the traditional Chinese medicine composition and an application of the traditional Chinese medicine composition in preparation of medicines for improving cognitive impairment of diabetes mellitus. The traditional Chinese medicine composition plays a role in improving cognitive impairment of diabetes mellitus mainly by inhibiting microglial cell inflammation, protecting hippocampal brain region nerve synaptic plasticity and the like.

The invention relates to a composition containing i) a DPP-4 inhibitor selected from an extract of dandelion (Taraxacum officinale), an extract of white mulberry (Morus alba), an extract of bitter melon (Momordica charantia), a hydrolysate of yeast (Saccharomyces cerevisiae), an extract of garlic (Allium sativum), an extract of grape (Vitis vinifera), an extract of turmeric (Curcuma longa), an extract of horseradish tree (Moringa oleifera) and an extract of fenugreek (Trigonella foenum-graecum); and ii) a GLP-1 analogue selected from a hydrolysate from yeast (Saccharomyces cerevisiae), an extract of white mulberry (Morus alba), an extract of Yerba mate (Ilex paraguariensis), an extract of Arabica coffee (Coffea arabica), an extract of purslane (Portulaca oleracea), an extract of bitter melon (Momordica charantia), an extract of queen's crape myrtle (Lagertroemia speciosa), an extract of apple (Malus domestica), an extract of cinnamon (Cinnamomum verum) and an extract of fenugreek (Trigonella foenum-graecum); and iii) a GLP-1 secretion promoter selected from inulin, gum arabic, an extract of bitter melon (Momordica charantia), an extract of purslane (Portulaca oleracea), an extract of common barberry (Berberis vulgaris), an extract of arabica coffee (Coffea arabica), an extract of Dahurian angelica (Angelica dahurica), an extract of turmeric (Curcuma longa) and an extract of fenugreek (Trigonella foenum-graecum), wherein, from each group i)-iii), at least one ingredient is selected and in total at least three different ingredients are selected.

Botanical or bacterial extracts and methods are provided for treating the skin and other tissues by applying certain botanical or bacterial extracts, such as Acronychia acidula, Licaria vernicosa, Calendula officinalis, Trigonella foenum-graecum or Actimomyces bacteria, to the skin or other tissue.

A system for the production and characterization of high-strength limestone suspensions using plant-based natural surfactants, comprising: a) a limestone processing plant for the production of limestone powder with a particle size of no more than 106 microns; b) a plant for the production of natural surfactants configured to produce an aqueous extract of Trigonella Foenum-Graecum seeds as a dispersing agent; c) a slurry formulation unit configured to mix the limestone powder with water in solids concentrations of 25 to 65 wt.% in the presence of the aqueous extract; d) a surface tension measuring unit for determining the critical micelle concentration of the aqueous extract; and e) a rheological characterization unit for analyzing the flow behavior of limestone suspensions at shear rates of 50 to 1000 s-1 is configured.