5 results about "Specific mass" patented technology

A golf club head having discreet regions of specific mass relationships, including a lightweight forward portion, to achieve specific mass properties and performance.

The invention belongs to the technical field of biological medicine, and particularly relates to an apatinib-loaded engineered bacterial membrane vesicle and a preparation method and application thereof.The engineered bacterial membrane vesicle is prepared by mixing apatinib and a membrane vesicle derived from rodent bacillus in a PBS according to a specific mass ratio; incubating at 37 DEG C for 4 hours, removing free drugs by using a 100kDa ultrafiltration membrane, and concentrating; and washing with PBS to obtain a final product. Experimental results show that the engineered bacterial membrane vesicles can effectively inhibit malignant biological behaviors such as proliferation of breast cancer cells and significantly inhibit tumor growth in an animal model; mechanism research shows that the compound can effectively activate the anti-tumor immune response of the body; safety evaluation shows that the engineered bacterial membrane vesicle has no toxic or side effect; in conclusion, the engineered bacterial membrane vesicle provided by the invention has dual advantages of chemotherapy and immunotherapy, is good in safety, and has important application value in development of breast cancer treatment drugs.

The invention discloses a preparation method of a flexible wrinkled surface. Comprising the following steps: mixing a PDMS matrix and a curing agent according to a specific mass ratio to form a prepolymer, and heating and curing after defoaming to obtain a flexible PDMS substrate; applying uniaxial or biaxial drawing force to the flexible PDMS substrate to deform the flexible PDMS substrate; keeping a stretching state, removing bubbles from newly prepared prepolymers with the same proportion, coating the prepolymers on a substrate, and heating and curing to form a double-layer flexible structure; the drawing force is released, and the PDMS film is compressed due to deformation recovery of the substrate to generate a wrinkle structure. Controllable adjustment of the size of the wrinkle structure can be achieved by adjusting and controlling the stretching direction and amplitude, the preparation material is single, the process is simple, cost is low, the period is short, controllability is high, the method is suitable for large-scale production, the problems that in the prior art, a flexible wrinkle surface preparation process is complex, cost is high, and large-scale production is difficult are solved, and the method is suitable for large-scale production. The method has a wide application prospect in the fields of flexible electronics, biomedical engineering, optical engineering and the like.

It suppresses the decrease in creatine content over time. [Solution] The topical composition contains creatine and creatinine in a specific mass ratio.

A golf club head having discreet regions of specific mass relationships, including a lightweight forward portion, to achieve specific mass properties and performance.